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| Product | Description | |
|---|---|---|
| SpStrongylocin 1 | SpStrongylocin 1 is an antimicrobial peptide isolated from Strongylocentrotus purpuratus. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Ile-Phe-Asn-Ser-Ile-Tyr-His-Arg-Lys-Cys-Val-Val-Lys-Asn-Arg-Cys-Glu-Thr-Val-Ser-Gly-His-Lys-Thr-Cys-Lys-Asp-Leu-Thr-Cys-Cys-Arg-Ala-Val-Ile-Phe-Arg-His-Glu-Arg-Pro-Glu-Val-Cys-Arg-Pro-Ser-Thr. |  |
| SpStrongylocin 2 | SpStrongylocin 2 is an antimicrobial peptide isolated from Strongylocentrotus purpuratus. It has activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Trp-Asn-Pro-Phe-Arg-Lys-Leu-Tyr-Arg-Lys-Glu-Cys-Asn-Asp-Val-Thr-Ser-Cys-Asp-Thr-Val-Ser-Gly-Val-Lys-Thr-Cys-Thr-Lys-Lys-Asn-Cys-Cys-His-Arg-Lys-Phe-Phe-Gly-Lys-Thr-Ile-Leu-Lys-Ala-Pro-Glu-Cys-Thr-Val-Ile-Ser. | |
| SPT-IN-1 | SPT-IN-1 (compound 1) is an orally active and potent SPT (serine palmitoyl transferase) inhibitor, with an IC50 of 5.19 nM for hSPT1. SPT-IN-1 can be used for type 2 diabetes and dyslipidemia research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1933533-18-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-125351. |  |
| SPUTOLYSIN Reagent - CAS 578517 | SPUTOLYSIN Reagent - CAS 578517. Uses: For analytical and research use. CAS No. 3483-12-3. Catalog: AP3483123-A. |  |
| S-PVC | S-PVC. |  |
| SQ109 | SQ109 is a potent inhibitor of the trypomastigote form of the parasite, with IC50 for cell killing of 50±8 nM. SQ109, targets MmpL3, is an antitubercular agent. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 722041. CAS No. 502487-67-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14989. | |
| SQ22536 | SQ22536 (9-(tetrahydrofuran-2-yl)-9h-purin-6-amine) is an inhibitor of adenylyl cyclase with an IC50 of 1.4 μM. It can inhibit PGE1-stimulated increases in cAMP levels in intact human platelets. Group: Inhibitors. Alternative Names: 9-(tetrahydrofuran-2-yl)-9h-purin-6-amine. CAS No. 17318-31-9. Pack Sizes: 10mg. Product ID: S8283. Formula: C9H11N5O. Smiles: C1CC(OC1)N2C=NC3=C(N=CN=C32)N. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| SQ22536 | SQ22536 is an effective adenylate cyclase (AC) inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 17318-31-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-100396. | |
| SQ 22536 | SQ 22536. Group: Biochemicals. Grades: Purified. CAS No. 17318-31-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| SQLE-IN-1 | SQLE-IN-1 (compound 19) is a squalene epoxidase (SQLE) inhibitor. SQLE-IN-1 inhibits the proliferation and migration of Huh7 cells. SQLE-IN-1 inhibits the cell cholesterol generation. SQLE-IN-1 increases the expression of PTEN and inhibits PI3K and AKT[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1019169-83-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160093. | |
| SQSTM1 / p62 Antibody [D16H4] | p62 (Sequestosome-1),p62 Ick ligand,p62/SQSTM1,SQSTM1,SQSTM1 / p62,SQSTM1/p62. Group: Antibodies. Alternative Names: p62 (Sequestosome-1),p62 Ick ligand,p62,SQSTM1. Pack Sizes: 20ul. Product ID: F0106. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Squalamine | Squalamine (MSI-1256) is an aminosterol compound with broad-spectrum antiviral activity. Squalamine makes cells less conducive to certain viral replication by altering the electrostatic interactions in the inner membrane of host cells. Squalamine also has antibacterial and antitumor activities. Squalamine has broad-spectrum antibacterial activity against Gram-negative and Gram-positive bacteria, fungi and protozoa. Squalamine inhibits tumor-related angiogenesis and the growth of human breast cancer cells. Squalamine restores the function of enteric nervous system in Parkinson,s disease mouse models[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MSI-1256; ENT-01 free acid. CAS No. 148717-90-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-16468. | |
| Squalamine | Squalamine. Alternative Names: 3beta-N-1-(N-[3-(4-Aminobutyl)]- 1,3-diaminopropane)-7alpha,24R-dihydroxy-5alpha-cholestane 24-sulfate. CAS No. 148717-90-2. Purity: 95%+. Product ID: ACM148717902. Molecular formula: C34H65N3O5S. Mole weight: 628. IUPAC Name: [(3R,6R)-6-[(3S,5R,7R,8R,9S,10S,13R,14S,17R)-3-[3-(4-Aminobutylamino)propylamino]-7-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylheptan-3-yl] hydrogen sulfate. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Squalamine lactate | Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity, and used for the treatment of neovascular age-related macular degeneration. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MSI-1256F. CAS No. 320725-47-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-16467. | |
| Squalane | 100g Pack Size. Group: Building Blocks, Organics. Formula: [(CH3)2CH(CH2)3CH(CH3)(CH2)3CH(CH3)CH2CH2]2. CAS No. 111-01-3. Prepack ID 13053317-100g. Molecular Weight 422.81. See USA prepack pricing. |  |
| Squalane | Squalane. CAS No. 111-01-3. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  |
| Squalane | Squalane. Group: Biochemicals. Alternative Names: 2,6,10,15,18,23-Hexamethyltetracosane. Grades: Highly Purified. CAS No. 111-01-3. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C30H62. US Biological Life Sciences. | Worldwide |
| Squalane-d62 | Isotope labelled Squalane is used as an emollient and moisturizer in cosmetic applications. Group: Biochemicals. Grades: Highly Purified. CAS No. 16514-83-3. Pack Sizes: 10mg, 25mg. Molecular Formula: C30D62, Molecular Weight: 485.2. US Biological Life Sciences. | Worldwide |
| Squalane-d62 | Squalane-d62 is the deuterium labeled Squalane[1]. Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 16514-83-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N7113S. | |
| Squalane-[d62] | Squalane-[d62]. Synonyms: Squalane-d62; 2,6,10,15,19,23-Hexakis[(2H3)methyl](2H44)tetracosane. Grade: 95% atom D. CAS No. 16514-83-3. Molecular formula: C30D62. Mole weight: 485.2. | |
| Squalene | Squalene. Alternative Names: 2,6,10,15,19,23-Hexamethyltetracosa-2,6,10,14,18,22-hexaene. CAS No. 111-02-4. Purity: 95%. Product ID: CI-OT-0037. Molecular formula: C30H50. Mole weight: 410.72 g/mol. IUPAC Name: (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Squalene | Squalene. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10g, 25g, 50g. US Biological Life Sciences. | Worldwide |
| Squalene | Squalene Inhibitor. Uses: Scientific use. Product Category: T4749. CAS No. 111-02-4. |  |
| Squalene | Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Super Squalene; trans-Squalene; AddaVax. CAS No. 111-02-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1214. | |
| squalene-hopanol cyclase | The enzyme produces the cyclization products hopene (cf. EC 5.4.99.17) and hopanol from squalene at a constant ratio of 5:1. Group: Enzymes. Synonyms: squalene-hopene cyclase (ambiguous). Enzyme Commission Number: EC 4.2.1.129. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4970; squalene-hopanol cyclase; EC 4.2.1.129; squalene-hopene cyclase (ambiguous). Cat No: EXWM-4970. |  |
| squalene-hopene cyclase | The enzyme also produces the cyclization product hopan-22-ol by addition of water (cf. EC 4.2.1.129, squalene hopanol cyclase). Hopene and hopanol are formed at a constant ratio of 5:1. Group: Enzymes. Enzyme Commission Number: EC 5.4.99.17. CAS No. 76600-69-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5556; squalene-hopene cyclase; EC 5.4.99.17; 76600-69-6. Cat No: EXWM-5556. | |
| Squalene Liposome | The liposome contains squalene, which can be used as adjuvant to enhance the immune response. It is only for research purposes. Group: Liposomal vaccine or adjuvant. |  |
| squalene methyltransferase | Two isoforms differing in their specificity were isolated from the green alga Botryococcus braunii BOT22. TMT-1 gave more of the dimethylated form whereas TMT2 gave more of the monomethylated form. Group: Enzymes. Synonyms: TMT-1; TMT-2. Enzyme Commission Number: EC 2.1.1.262. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1867; squalene methyltransferase; EC 2.1.1.262; TMT-1; TMT-2. Cat No: EXWM-1867. | |
| squalene monooxygenase | A flavoprotein (FAD). This enzyme, together with EC 5.4.99.7 lanosterol synthase, was formerly known as squalene oxidocyclase. The electron donor is EC 1.6.2.4, NADPH-hemoprotein reductase. Group: Enzymes. Synonyms: squalene epoxidase; squalene-2,3-epoxide cyclase; squalene 2,3-oxidocyclase; squalene hydroxylase; squalene oxydocyclase; squalene-2,3-epoxidase. Enzyme Commission Number: EC 1.14.14.17. CAS No. 9029-62-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0914; squalene monooxygenase; EC 1.14.14.17; 9029-62-3; squalene epoxidase; squalene-2,3-epoxide cyclase; squalene 2,3-oxidocyclase; squalene hydroxylase; squalene oxydocyclase; squalene-2,3-epoxidase. Cat No: EXWM-0914. | |
| squalene synthase | This microsomal enzyme catalyses the first committed step in the biosynthesis of sterols. The enzyme from yeast requires either Mg2+ or Mn2+ for activity. In the absence of NAD(P)H, presqualene diphosphate (PSPP) is accumulated. When NAD(P)H is present, presqualene diphosphate does not dissociate from the enzyme during the synthesis of squalene from farnesyl diphosphate (FPP). High concentrations of FPP inhibit the production of squalene but not of PSPP. Group: Enzymes. Synonyms: farnesyltransferase; presqualene-diphosphate synthase; presqualene synthase; squalene synthetase; farnesyl-diphosphate farnesyltransferase; SQS. Enzyme Commission Number: EC 2.5.1.21. CAS No. 9077-14-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2758; squalene synthase; EC 2.5.1.21; 9077-14-9; farnesyltransferase; presqualene-diphosphate synthase; presqualene synthase; squalene synthetase; farnesyl-diphosphate farnesyltransferase; SQS. Cat No: EXWM-2758. | |
| Squalestatin A | It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Synonyms: Zaragozic acid A; squalestatin 1; Squalestatin; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate 5-(4,6-dimethyl-2-octenoate), (5(2E,4S,6S),7S)-; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate 5-[(2E,4S,6S)-4,6-dimethyl-2-octenoate], (7S)-; Squalestatin S1. Grade: >98% by HPLC. CAS No. 142561-96-4. Molecular formula: C35H46O14. Mole weight: 690.73. | |
| Squalestatin B | It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Synonyms: L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 5-[(2E,4S,6S)-4,6-dimethyl-2-octenoate], (7S)-; L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 5-(4,6-dimethyl-2-octenoate), [5(2E,4S,6S),7S]-; Squalestatin 2; Squalestatin S2. CAS No. 142505-91-7. Molecular formula: C33H44O13. Mole weight: 648.70. | |
| Squalestatin C | It is a squalene synthase inhibitor produced by the strain of Phoma sp. C2932. It inhibits squalene synthase in mammalian (rat liver) and Candida albicans, and has a broad-spectrum antifungal effect. Synonyms: L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-10-methylene-12-(phenylmethyl)-, 11-acetate, (7S)-; Squalestatin 3; Squalestatin H1. CAS No. 142505-92-8. Molecular formula: C25H30O13. Mole weight: 538.50. | |
| Squamatic acid | Squamatic acid. Synonyms: Squamatsaure; 2-Hydroxy-4-methoxy-6-methyl-1,3-benzenedicarboxylic acid 1-(4-carboxy-3-hydroxy-2,5-dimethylphenyl) ester; 1,3-Benzenedicarboxylic acid, 2-hydroxy-4-methoxy-6-methyl-, 1-(4-carboxy-3-hydroxy-2,5-dimethylphenyl) ester; 2-Oxy-6-methoxy-4-methyl-isophthalsaeure-3-(3-oxy-2,5-dimethyl-4-carboxy-phenylester). CAS No. 569-36-8. Molecular formula: C19H18O9. Mole weight: 390.34. | |
| Squarain-carboxylate N-succinimidyl ester | Squarain-carboxylate N-succinimidyl ester. Alternative Names: SQ-NHS, AC1NOW1Z, CTK8E7978, 154161-81-6, 4-[(5-chloro-1,3,3-trimethylindol-1-ium-2-yl)methylidene]-2-[[5-(2,5-dioxopyrrolidin-1-yl)oxycarbonyl-1-ethyl-3,3-dimethylindol-2-ylidene]methyl]-3-oxocyclobuten-1-olate. CAS No. 154161-81-6. Purity: 96%. Product ID: ACM154161816. Molecular formula: C34H32ClN3O6. Mole weight: 614.09. IUPAC Name: 4-[(5-chloro-1,3,3-trimethylindol-1-ium-2-yl)methylidene]-2-[[5-(2,5-dioxopyrrolidin-1-yl)oxycarbonyl-1-ethyl-3,3-dimethylindol-2-ylidene]methyl]-3-oxocyclobuten-1-olate. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Squaric Acid | Crystalline, purity 99+%. Synonym: 3,4-Dihydroxy-3-cyclobutene-1,2-dione. CAS No. 2892-51-5. Pack Sizes: Typically in stock: 10g, 50g. Mole weight: 114.06. MP/BP: M.P. >300. Order No: FR-0532. |  Frinton Laboratories |
| Squaric Acid-[d2] | Squaric Acid-[d2] is the labelled analogue of Squaric Acid. Synonyms: Squaric acid-d2; 3,4-Dihydroxy-3-cyclobutene-1,2-dione-d2. Grade: 95% by CP; 98% atom D. CAS No. 31150-56-8. Molecular formula: C4D2O4. Mole weight: 116.07. | |
| Squarunkin A | Squarunkin A is a potent and selective UNC119-cargo interaction inhibitor, interrupting the UNC119A-myristoylated Src N-terminal peptide interaction (IC50=10 nM). Squarunkin A interferes with the activation of Src kinase in cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2101958-02-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-127002. | |
| Squaw Vine Powder | Squaw Vine Powder. |  CA, FL & NJ |
| SR-0813 | SR-0813 is a potent and selective ENL/AF9 YEATS domain inhibitor. SR-0813 has IC50 and EC50 values of 25 nM and 205 nM for ENL YEATS domain, respectively. SR-0813 has IC50 and EC50 values of 311 nM and 76 nM (CETSA) for AF9 YEATS domain, respectively. SR-0813 binds MAP3K19 with over 100-fold lower affinity (Kd=3.5 μM) than ENL YEATS (Kd=30 nM). SR-0813 can be used for the research of acute leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2597186-19-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145409. | |
| SR0987 | SR0987, a SR1078 analog, is a RORγt agonist, with an EC50 of 800 nM. SR0987 increases IL17 expression while repressing the expression of PD-1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 303126-97-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101454. | |
| SR1001 | SR1001 is a selective RORα and RORγt inverse agonist with Kis 172 and 111 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1335106-03-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-13421. | |
| SR10221 | SR10221, a noncovalent inverse agonist of PPARγ, represses downstream PPARγ target genes leading to growth inhibition in bladder cancer cell lines[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1415321-64-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150308. | |
| SR1078 | SR1078 is a selective agonist of retinoic acid receptor-related orphan receptor α/γ (RORα/RORγ). SR1078 directly binds to the ligand binding domain of RORα and RORγ and increases the transcriptional activity of these receptors, leading to stimulation of RORα/γ target gene transcription[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1246525-60-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14422. | |
| SR-1114 | SR-1114 is a PROTAC degrader targeting ENL. SR-1114 degrades ENL in a CRBN-dependent manner and selectively downregulates ENL target genes. SR-1114 can promote the differentiation of acute myeloid leukemia cells. SR-1114 can be used in tumor research. (Pink: ENL ligand (HY-145409); Black: Linker; Blue: E3 Ligand (HY-14658))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2769141-82-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115881. | |
| SR11237 | SR11237 (BMS-649) GMP is SR11237 (HY-107413) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. SR11237 is a RXR activator and lipid metabolism regulator that promotes the differentiation of induced neural stem cells into dopaminergic (TH-positive) neurons. SR11237 induces transcriptional regulation of lipogenic genes and cholesterol transporters, increases glycosaminoglycan release, and elevates total cellular triglyceride levels. SR11237 promotes heterodimerization of RXR with Nurr1, thereby enhancing tyrosine hydroxylase expression and facilitating dopamine release. SR11237 produces a synergistic effect when used in combination with bFGF/EGF. SR11237 is mainly used in studies related to osteoarthritis and Parkinson's disease[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-649. CAS No. 146670-40-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107413. | |
| SR 11237 | SR 11237. Group: Biochemicals. Grades: Purified. CAS No. 146670-40-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 11302 | SR 11302. Group: Biochemicals. Grades: Purified. CAS No. 160162-42-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| SR 11302 | SR 11302. CAS No: 160162-42-5 |  Sarchem Laboratories New Jersey NJ |
| SR 11302 | SR 11302 is an activator protein-1 (AP-1) transcription factor inhibitor. SR 11302 is a retinoid that specifically inhibits AP-1 activity without activating the transcription of retinoic acid response element (RARE)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 160162-42-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15870. | |
| SR12418 | SR12418 is a REV-ERB-specific synthetic ligand with IC50s of 68 nM and 119 nM for REV-ERBα and REV-ERBβ, respectively. SR12418 can be used in experimental autoimmune encephalomyelitis (EAE) and colitis research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1801185-08-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148103. | |
| SR12813 | SR12813 (GW 485801) is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, with an IC50 value of 0.85 μM[1][2]. SR12813 is also an efficient agonist of human pregnane X receptor (hPXR). SR12813 can strongly bind to hPXR but not to mouse PXR (mPXR)[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GW 485801. CAS No. 126411-39-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-100793. | |
| SR 12813 | SR 12813. Group: Biochemicals. Grades: Purified. CAS No. 126411-39-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 140333 | SR 140333. Group: Biochemicals. Grades: Purified. CAS No. 153050-21-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 141716A | SR 141716A. Group: Biochemicals. Grades: Purified. CAS No. 158681-13-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 142948 | SR 142948 is an orally active and selective non-peptide neurotensin receptor (NT) antagonist with IC50s of 1.19 nM, 0.32 nM, 3.96 nM in h-NTR1-CHO cells, HT-29 cells, and adult rat brain, respectively. SR 142948 antagonizes NT-induced inositol monophosphate formation in HT-29 cells with an IC50 of 3.9 nM. SR 142948 blocks hypothermia, analgesia and steering behavior induced by NT in vivo. SR 142948 shows blood-brain permeability and can be used in study of psychiatric disorders[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 184162-64-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107664. | |
| SR 142948 | SR 142948. Group: Biochemicals. Grades: Purified. CAS No. 184162-64-9. Pack Sizes: 1mg, 10mg. US Biological Life Sciences. | Worldwide |
| SR144528 | SR144528 is a potent and selective CB2 receptor antagonist with a Ki of 0.6 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 192703-06-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13439. | |
| SR 144528 | SR 144528. Group: Biochemicals. Alternative Names: (1S-endo)-5-(4-Chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-(1, 3, 3-trimethylbicyclo[2. 2. 1]hept-2-yl)-1H-Pyrazole-3-carboxamide. Grades: Highly Purified. CAS No. 192703-06-3. Pack Sizes: 5mg. Molecular Formula: C29H34ClN3O, Molecular Weight: 476.05. US Biological Life Sciences. | Worldwide |
| SR 146131 | SR 146131 is a potent, orally available, and selective nonpeptide (cholecystokinin 1) receptor agonist. Uses: Scientific research. Category: Signaling pathways. CAS No. 221671-61-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11077. | |
| SR15006 | SR15006 is a inhibitor of Krüppel-like factor 5 (KLF5) with an IC50 of 41.6 nM in DLD-1/pGL4.18hKLF5p cells)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2505001-54-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139691. | |
| SR 16584 | SR 16584. Group: Biochemicals. Alternative Names: 1,3-Dihydro-1-[(3-exo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-2H-indol-2-one. Grades: Highly Purified. CAS No. 1150153-86-8. Pack Sizes: 10mg. Molecular Formula: C17H22N2O, Molecular Weight: 270.37. US Biological Life Sciences. | Worldwide |
| SR1664 | SR1664 is a PPARγ antagonist. SR1664 binds to PPARγ and potently inhibits Cdk5-mediated PPARγ phosphorylation (IC50=80 nM; Ki= 28.67 nM)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1338259-05-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12483. | |
| SR 1664 | SR 1664. Group: Biochemicals. Grades: Purified. CAS No. 1338259-05-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR 16832 | SR 16832 is a dual-site covalent, orthosteric and allosteric PPARγ antagonist. SR 16832 activates the TGF-β signaling pathway and upregulates the expression of Vimentin and Fibronectin (Fibronectin). SR 16832 is toxic to bronchial epithelium. SR 16832 can be used in research related to type 2 diabetes and pulmonary fibrosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2088135-12-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112247. | |
| SR17018 | SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 2134602-45-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111454. | |
| SR-18292 | SR-18292 is a PPAR gamma coactivator-1α (PGC-1α) inhibitor, which increases PGC-1α acetylation, suppresses gluconeogenic gene expression and reduces glucose production in hepatocytes. Uses: Scientific research. Category: Signaling pathways. CAS No. 2095432-55-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101491. | |
| SR18662 | SR18662 is a potent inhibitor of Krüppel-like factor five (KLF5) with an IC50 of 4.4 nM and an analogue of ML264 (HY-19994) with improved inhibitory potency against colorectal cancer cells. SR18662 can be used for the study of colorectal cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2505001-62-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-136530. | |
| SR 202 | SR 202. Group: Biochemicals. Grades: Purified. CAS No. 76541-72-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SR2211 | SR2211 is a potent, selective synthetic RORγ modulator and functions as an inverse agonist, with a Ki of 105 nM and an IC50 of ~320 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1359164-11-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16998. | |
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