A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Spermine tetrahydrochloride is a polyamine that binds to and modulates NMDA receptor channel. Spermine also acts as a GluR inhibitor, PLCα inhibitor and PLCδ activator. Uses: Found widely in nature and essential for tissue growth; used as a tool in biochemical research; spermine is a polyamine involved in cellular metabolism found in all eukaryotic cells. formed from spermidine, it is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria. spermine is associated with nucleic acids and is thought to stabilize helical structure, in particular, in viruses. Synonyms: N,N'-Bis(3-aminopropyl)-1,4-butanediamine tetrahydrochloride; Neuridine tetrahydrochloride; Musculamine tetrahydrochloride. Grades: >98.0%(T)(N). CAS No. 306-67-2. Molecular formula: C10H26N4.4HCl. Mole weight: 348.19.
Spermine Tetrahydrochloride
Spermine Tetrahydrochloride is an inhibitor of NOS1, NMDA, GluR, and PLCα. A useful reactant for Surface-enhanced Raman spectroscopy (SERS) characterization of abasic sites in DNA duplexes. Biogenic polyamine; NMDA glutamate receptor agonist/antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 306-67-2. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C??H??Cl?N?, Molecular Weight: 348.18. US Biological Life Sciences.
Worldwide
spermosin
The enzyme from the ascidian (Prochordate) Halocynthia roretzi is localized in the sperm head, and released during sperm activation. A proline-rich region is involved in binding to the vitelline coat of the egg. Belongs in peptidase family S1 (trypsin family). Group: Enzymes. Enzyme Commission Number: EC 3.4.21.99. CAS No. 89925-67-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4191; spermosin; EC 3.4.21.99; 89925-67-7. Cat No: EXWM-4191.
Sperm surface protein Sp17 (103-111)
Sperm surface protein Sp17 (103-111) is a truncated fragment of Sperm surface protein Sp17. Sperm surface protein Sp17 is a sperm surface zona pellucida binding protein which helps to bind spermatozoa to the zona pellucida with high affinity. Synonyms: Cancer/testis antigen 22 (103-111); Sp17-1 (103-111); Sperm autoantigenic protein 17 (103-111).
Spesolimab
Spesolimab (BI 655130) is a mouse-derived humanized IgG1k antibody against IL-36R. IL-36 plays an important role in the immune system and Spesolimab is being investigated in palmoplantar pustulosis (PPP). Spesolimab was associated with a reduction in biomarkers associated with the innate, Th1/Th17 and neutrophil pathways [1] [2] [3] [4]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BI 655130. CAS No. 2097104-58-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99396.
Spesolimab
Spesolimab is a monoclonal antibody that targets interleukin-36 receptor (IL-36R). Spesolimab has been approved for the treatment of generalized pustular psoriasis (GPP) flares in adults. Synonyms: Spevigo. CAS No. 2097104-58-8.
Spexin
Spexin is an endogenous satiety-inducing peptide and a potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 = 45.7 and 112.2 nM, respectively), displaying no significant activity at galanin receptor 1. Spexin inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet-induced obese mice and rats. It exhibits anxiolytic effects in vivo. Synonyms: SPX; NPQ (human, mouse, bovine); H-Asn-Trp-Thr-Pro-Gln-Ala-Met-Leu-Tyr-Leu-Lys-Gly-Ala-Gln-NH2; L-asparagyl-L-tryptophyl-L-threonyl-L-prolyl-L-glutaminyl-L-alanyl-L-methionyl-L-leucyl-L-tyrosyl-L-leucyl-L-lysyl-glycyl-L-alanyl-L-glutaminamide; Neuropeptide Q; Spexin (36-49) amidated. Grades: ≥95%. CAS No. 1370290-58-6. Molecular formula: C74H114N20O19S. Mole weight: 1619.91.
Spexin
Spexin is a conserved peptide plays roles of neurotransmitter/neuromodulator and endocrine factor. Spexin peptide contains numerous aromatic amino acids and is probably amidated [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Neuropeptide Q. CAS No. 1370290-58-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1723.
Sp-GDP-α-S
Sp-GDP-α-S is a GDP binding proteins regulator with high stability, which is used for characterization of GDP-responsive receptors and determination of their stereospecificity. Synonyms: Guanosine- 5'- O- (1- thiodiphosphate), Sp- isomer, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 71481-45-3. Molecular formula: C10H15N5O10P2S (free acid). Mole weight: 459.3 (free acid).
SPH3127
SPH3127 (DRI 18) is a novel, highly potent, and orally active direct renin inhibitor (recombinant human-renin IC 50 =0.4 nM, human plasma renin activity IC 50 =0.45 nM). SPH3127 shows antihypertensive effect and can be used in essential hypertension research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1399849-02-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151111.
SPH5030
SPH5030 is a selective and irreversible HER2 inhibitor. SPH5030 inhibits HER2 WT and EGFR WT with IC 50 s of 3.51 and 8.13 nM, respectively. SPH5030 shows excellent activities against HER2 mutants. SPH5030 can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2364326-23-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-143319.
Spheniscin-1 is an antimicrobial peptide isolated from Aptenodytes patagonicus. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Synonyms: Ser-Phe-Gly-Leu-Cys-Arg-Leu-Arg-Arg-Gly-Phe-Cys-Ala-His-Gly-Arg-Cys-Arg-Phe-Pro-Ser-Ile-Pro-Ile-Gly-Arg-Cys-Ser-Arg-Phe-Val-Gln-Cys-Cys-Arg-Arg-Val-Trp.
S-Phenyl Benzenethiosulfonate
S-Phenyl Benzenethiosulfonate. Group: Biochemicals. Alternative Names: NSC 74657; Phenyl Benzenethiosulfonate; Phenyl Phenylthio Sulfone; S-Phenyl Benzene monothiosulfonate; S-Phenyl Benzenethiosulfonate. Grades: Highly Purified. CAS No. 1212-08-4. Pack Sizes: 2.5g. Molecular Formula: C12H10O2S2, Molecular Weight: 250.34. US Biological Life Sciences.
Worldwide
S-Phenyl-D5-L-cysteine
S-Phenyl-D5-L-cysteine. Group: Biochemicals. Alternative Names: 2-Amino-3-phenylsulfanyl-D5-propionic Acid. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C9H6D5NO2S, Molecular Weight: 202.28. US Biological Life Sciences.
An important isoopically labeled metabolite of benzene. Group: Biochemicals. Alternative Names: N-Acetyl-S-phenyl-d5-L-cysteine. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
S-Phenyl-L-cysteine
S-Phenyl-L-cysteine. Group: Biochemicals. Alternative Names: 2-Amino-3-phenylsulfanyl-propionic acid. Grades: Highly Purified. CAS No. 34317-61-8. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C9H11NO2S. US Biological Life Sciences.
Worldwide
S-Phenyl-L-cysteine
. Uses: Inhibitor of enzyme. Synonyms: H-Cys(Phenyl)-OH. Grades: 98%. CAS No. 34317-61-8. Molecular formula: C11H23NO2S. Mole weight: 197.25.
S-Phenylmercapturic acid
S-Phenylmercapturic acid. Group: Biochemicals. Alternative Names: N-Acetyl-S-phenyl-L-cysteine; N-Acetyl-3-(phenylthio)alanine, NSC 17197. Grades: Highly Purified. CAS No. 4775-80-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 200mg. Molecular Formula: C11H13NO3S. US Biological Life Sciences.
Worldwide
S-Phenylmercapturic acid
S-Phenylmercapturic acid, a metabolite of benzene, can be used as a biomarker, identified by GC, HPLC (UV or fluorescence detection), GC-MS, LC-MS/MS or immunoassay [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4775-80-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130189.
An important metabolite of Benzene. Group: Biochemicals. Alternative Names: N-Acetyl-S-phenyl-L-cysteine. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Spherical Graphite C Powder
Spherical Graphite C Powder. Uses: Used for high-end lithium ion prismatic, cylindrical polymer battery. Group: Element powders. CAS No. 7782-42-5. 99.98%.
Spherical HEA Powder, Fe-Co-Ni-Cr-Al
Spherical Refractory High-entropy Alloy (HEA) Powder (Fe-Co-Ni-Cr-Al) has high strength, high hardness, good high-temperature performance, excellent wear resistance, and corrosion resistance, which can be used in 3D printing. Alfa Chemistry provides spherical HEA Powder (Fe-Co-Ni-Cr-Al) with high fluidity and the best quality. Uses: Spherical heas powder has gained interest for its promising properties including enhanced irradiation resistance, high-temperature strength, and corrosion resistance. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements.
Alfa Chemistry offers high-quality Spherical High-entropy Alloy Powder AlCoCr2FeMo0.5Ni with competitive pricing. Uses: Spherical high-entropy alloy powder alcocr2femo0.5ni is suitable for 3d printing, hot isostatic pressing, injection molding, laser cladding, and so on. Group: High entropy alloys. Pack Sizes: Our Spherical High-entropy Alloy Powder AlCoCr2FeMo0.5Ni is carefully handled during storage and transportation to preserve the quality of our product in its original condition.
Spherical Powder-Cobalt Based Alloys (CoCrMo)
Cobalt-based alloys spherical Powder are widely used in the medical field because of their excellent corrosion resistance, mechanical properties, and biological properties. Our powder has the characteristics of high sphericity, good fluidity, high purity, large loose density, full density inside particles, no hollow powder. Uses: It is suitable for the production of guide vane and nozzle guide vane of aviation jet engines, industrial gas turbines, naval gas turbines, diesel nozzles, etc. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements.
Spherical Powder-Cobalt Based Alloys (CoCrMoW)
Spherical Cobalt-based alloys Powders are widely used in the medical field because of their excellent corrosion resistance, mechanical properties, and biological properties. Our powder has the characteristics of high sphericity, good fluidity, high purity, large loose density, full density inside particles, and no hollow powder. Uses: It is suitable for the production of guide vane and nozzle guide vane of aviation jet engines, industrial gas turbines, naval gas turbines, diesel nozzles, etc. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements.
Spherical Refractory High-entropy Alloy (HEA) Powder (Cr-Fe-Co-Ni) has high strength, high hardness, good high-temperature performance, excellent wear resistance, and corrosion resistance, which can be used in 3D printing. Alfa Chemistry provides spherical Refractory High-entropy Alloy (HEA) Powder (Cr-Fe-Co-Ni) with high fluidity at a competitive price. Uses: Spherical heas powder has gained interest for its promising properties including enhanced irradiation resistance, high-temperature strength, and corrosion resistance. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements.
High-entropy alloys are a new type of metal material composed of 4, 5, or more metal elements in nearly equal atomic ratios, also known as complex component alloys. As CrMnFeCoNi, which have high strength, high hardness, good high-temperature performance, excellent wear resistance, and corrosion resistance, which can be used in 3D printing. Uses: Spherical heas powder has gained interest for its promising properties including enhanced irradiation resistance, high-temperature strength, and corrosion resistance. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements.
Spherical Refractory High-entropy Alloy Powder (Al32.72Fe9.05Si7.24Mn) has high strength, high hardness, good high-temperature performance, excellent wear resistance, and corrosion resistance, which can be used in 3D printing. Alfa Chemistry supplies spherical Refractory High-entropy Alloy Powder (Al32.72Fe9.05Si7.24Mn) with high fluidity at a competitive price. Uses: Spherical heas powder has gained interest for its promising properties including enhanced irradiation resistance, high-temperature strength, and corrosion resistance. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements.
Spherical Refractory High-entropy Alloy Powder (AlCoCr2FeMo0.5Ni) has high strength, high hardness, good high-temperature performance, excellent wear resistance, and corrosion resistance, which can be used in 3D printing. Alfa Chemistry provides spherical Refractory High-entropy Alloy Powder (AlCoCr2FeMo0.5Ni) with high fluidity at a competitive price. Uses: Spherical heas powder has gained interest for its promising properties including enhanced irradiation resistance, high-temperature strength, and corrosion resistance. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements.
Spherical Refractory High-entropy Alloy Powder (Cu11.85Al3.2Mn0.1Ti) has high strength, high hardness, good high-temperature performance, excellent wear resistance, and corrosion resistance, which can be used in 3D printing. Alfa Chemistry provides spherical Refractory High-entropy Alloy Powder (Cu11.85Al3.2Mn0.1Ti) with high fluidity at a competitive price. Uses: Spherical heas powder has gained interest for its promising properties including enhanced irradiation resistance, high-temperature strength, and corrosion resistance. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements.
Spherical Refractory High-entropy Alloy Powder (Fe50Mn30Co10Cr10) has high strength, high hardness, good high-temperature performance, excellent wear resistance, and corrosion resistance, which can be used in 3D printing. Alfa Chemistry provides spherical Refractory High-entropy Alloy Powder (Fe50Mn30Co10Cr10) with high fluidity at a competitive price. Uses: Spherical heas powder has gained interest for its promising properties including enhanced irradiation resistance, high-temperature strength, and corrosion resistance. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements.
Spherical Refractory High-entropy Alloy Powder (HEA, Fe-Co-Ni-Cr-Mn) has high strength, high hardness, good high-temperature performance, excellent wear resistance, and corrosion resistance, which can be used in 3D printing. Alfa Chemistry provides spherical Refractory High-entropy Alloy Powder (Fe-Co-Ni-Cr-Mn) with high fluidity at a competitive price. Uses: Spherical heas powder has gained interest for its promising properties including enhanced irradiation resistance, high-temperature strength, and corrosion resistance. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements.
Alfa Chemistry supplies Spherical Refractory High-entropy Alloy Powder (HEA, V-Nb-Mo-Ta-W) with high fluidity at a competitive price. Uses: Spherical heas powder have gained interest for their promising properties including enhanced irradiation resistance, high-temperature strength, and corrosion resistance. Group: High entropy alloys. Pack Sizes: Vacuum packaging, 1kg/bag, 2kg/bag; iron drum lined with plastic bag 25 kg/drum; special packaging is available according to user requirements.
spheroidene monooxygenase
The enzyme is involved in spheroidenone biosynthesis and in 2,2'-dioxospirilloxanthin biosynthesis. The enzyme from Rhodobacter sphaeroides contains heme at its active site. Group: Enzymes. Synonyms: CrtA; acyclic carotenoid 2-ketolase; spirilloxanthin monooxygenase; 2-oxo-spirilloxanthin monooxygenase. Enzyme Commission Number: EC 1.14.15.9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0952; spheroidene monooxygenase; EC 1.14.15.9; CrtA; acyclic carotenoid 2-ketolase; spirilloxanthin monooxygenase; 2-oxo-spirilloxanthin monooxygenase. Cat No: EXWM-0952.
Spheroidenone
Spheroidenone. Group: Biochemicals. Alternative Names: 1-Methoxy-3,4-didehydro-1,2,7',8'-tetrahydro-?,?-caroten-2-one. Grades: Highly Purified. CAS No. 13836-70-9. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C41H58O2. US Biological Life Sciences.
Worldwide
Sph I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. GCATG↑C C↓GTACG. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer G, BSA. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned Sph I gene from Streptomyces phaeochromogenes. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0,1 mM EDTA; 1 mM DTT; 100 μg/ml BSA; 50% glycerol. Cat No: ET-1179RE.
Sphinganine
Sphinganine. Group: Biochemicals. Alternative Names: C18-Dihydrosphingosine; (2S,3R)-2-amino-1,3-octadecanediol. Grades: Highly Purified. CAS No. 764-22-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C18H39NO2. US Biological Life Sciences.
Worldwide
Sphinganine 1-phosphate
Sphinganine 1-phosphate (D-erythro-Dihydrosphingosine 1-phosphate) is a polar sphingolipid metabolite that regulates cell migration, differentiation, survival and complex physiological processes [1]. Uses: Scientific research. Group: Natural products. Alternative Names: D-erythro-Dihydrosphingosine 1-phosphate. CAS No. 19794-97-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-113116.
sphinganine-1-phosphate aldolase
A pyridoxal-phosphate protein. Group: Enzymes. Synonyms: dihydrosphingosine 1-phosphate aldolase; sphinganine-1-phosphate alkanal-lyase; sphinganine-1-phosphate lyase; sphinganine-1-phosphate palmitaldehyde-lyase. Enzyme Commission Number: EC 4.1.2.27. CAS No. 39391-27-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4866; sphinganine-1-phosphate aldolase; EC 4.1.2.27; 39391-27-0; dihydrosphingosine 1-phosphate aldolase; sphinganine-1-phosphate alkanal-lyase; sphinganine-1-phosphate lyase; sphinganine-1-phosphate palmitaldehyde-lyase. Cat No: EXWM-4866.
Sphinganine-1-phosphate (d18:0)
Sphinganine-1-phosphate is an antagonist of the sphingosine-1-phosphate (S1P1/EDG-1) receptor with Ki value of 15 nM. It is a lipid mediator particularly for HDL. Synonyms: D-erythro-sphinganine-1-phosphate; C18-dihydro Sphingosine-1-phosphate; Dihydro-D-erythro-Sphingosine-1-phosphate; D-erythro-Dihydro-D-sphingosine-1-phosphate; [R-(R*,S*)]-2-Amino-1,3-octadecanediol 1-(Dihydrogen Phosphate); (2S,3R)-Sphinganine 1-Phosphate; C18-Dihydrosphingosine 1-Phosphate; Dihydrosphingosine-1-phosphate; (2S,3R)-2-Amino-1,3-octadecanediol 1-(Dihydrogen Phosphate). Grades: ≥95%. CAS No. 19794-97-9. Molecular formula: C18H40NO5P. Mole weight: 381.49.
sphingolipid 10-desaturase
The enzyme, characterized from the marine diatom Thalassiosira pseudonana, produces an all-trans product. Similar triunsaturated sphingoid bases are found in some marine invertebrates. The enzyme determines the position of the double bond by its distance from the alcohol end of the sphingoid base, and contains a cytochrome b5 domain that acts as the direct electron donor to the active site of the desaturase. Group: Enzymes. Synonyms: desA (gene name). Enzyme Commission Number: EC 1.14.19.19. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0981; sphingolipid 10-desaturase; EC 1.14.19.19; desA (gene name). Cat No: EXWM-0981.
sphingolipid 4-desaturase
The enzyme, which has been characterized from plants, fungi, and mammals, generates a trans double bond at position 4 of sphinganine bases in sphingolipids. The preferred substrate is dihydroceramide, but the enzyme is also active with dihydroglucosylceramide. Unlike EC 1.14.19.29, sphingolipid 8-desaturase, this enzyme does not contain an integral cytochrome b5 domain and requires an external cytochrome b5. The product serves as an important signalling molecules in mammals and is required for spermatide differentiation. Group: Enzymes. Synonyms: dehydroceramide desaturase. Enzyme Commission Number: EC 1.14.19.17. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0979; sphingolipid 4-desaturase; EC 1.14.19.17; dehydroceramide desaturase. Cat No: EXWM-0979.
sphingolipid 8-(E)-desaturase
The enzyme, characterized from the yeasts Kluyveromyces lactis and Candida albicans and from the diatom Thalassiosira pseudonana, introduces a trans double bond at the 8-position of sphingoid bases in sphingolipids. The enzyme determines the position of the double bond by its distance from the alcohol end of the sphingoid base, and contains a cytochrome b5 domain that acts as the direct electron donor to the active site of the desaturase. The homologous enzymes from higher plants, EC 1.14.19.29, sphingolipid 8-(E/Z)-desaturase, act on phytosphinganine (4-hydroxysphinganine) and produces a mixture of trans and cis isomers. Group: Enzymes. Synonyms: 8-sphingolipid desaturase (ambiguous); 8 fatty acid desaturase (ambiguous); DELTA8-sphingolipid desaturase (ambiguous). Enzyme Commission Number: EC 1.14.19.18. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0980; sphingolipid 8-(E)-desaturase; EC 1.14.19.18; 8-sphingolipid desaturase (ambiguous); 8 fatty acid desaturase (ambiguous); DELTA8-sphingolipid desaturase (ambiguous). Cat No: EXWM-0980.
sphingolipid 8-(E/Z)-desaturase
The enzymes from higher plants convert sphinganine, 4E-sphing-4-enine and phytosphinganine into E/Z-mixtures of Δ8-desaturated products displaying different proportions of geometrical isomers depending on plant species. The nature of the actual desaturase substrate has not yet been studied experimentally. The enzymes contain an N-terminal cytochrome b5 domain that acts as the direct electron donor to the active site of the desaturase. The homologous enzymes from some yeasts and diatoms, EC 1.14.19.18, sphingolipid 8-(E)-desaturase, act on sphing-4-enine ceramides and produce only the trans isomer. Group: Enzymes. Synonyms: 8-sphingolipid desaturase (ambiguous); 8 fatty acid desaturase (ambiguous); DELTA8-sphingolipid desaturase (ambiguous). Enzyme Commission Number: EC 1.14.19.29. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0992; sphingolipid 8-(E/Z)-desaturase; EC 1.14.19.29; 8-sphingolipid desaturase (ambiguous); 8 fatty acid desaturase (ambiguous); DELTA8-sphingolipid desaturase (ambiguous). Cat No: EXWM-0992.
sphingolipid C4-monooxygenase
The enzyme, which belongs to the familiy of endoplasmic reticular cytochrome b5-dependent enzymes, is involved in the biosynthesis of sphingolipids in eukaryotes. Some enzymes are bifunctional and also catalyse EC 1.14.19.17, sphingolipid 4-desaturase. Group: Enzymes. Synonyms: sphinganine C4-monooxygenase; sphingolipid C4-hydroxylase; SUR2 (gene name); SBH1 (gene name); SBH2 (gene name); DEGS2 (gene name). Enzyme Commission Number: EC 1.14.18.5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0967; sphingolipid C4-monooxygenase; EC 1.14.18.5; sphinganine C4-monooxygenase; sphingolipid C4-hydroxylase; SUR2 (gene name); SBH1 (gene name); SBH2 (gene name); DEGS2 (gene name). Cat No: EXWM-0967.
sphingolipid C9-methyltransferase
The enzyme, characterized from the fungi Komagataella pastoris and Fusarium graminearum, acts only on ceramides and has no activity with free sphingoid bases or glucosylceramides. Group: Enzymes. Enzyme Commission Number: EC 2.1.1.317. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1925; sphingolipid C9-methyltransferase; EC 2.1.1.317. Cat No: EXWM-1925.
Sphingomyelin is a eukaryotic sphingolipid and one of the major constituents of cell membranes and particularly abundant in the myelin sheath that surrounds neuronal axons. Sphingomyelin plays an important role in cell processes, the regulation of inflammatory responses, and signal transduction. Sphingomyelin metabolism is associated with various central nervous system diseases and Niemann - Pick disease [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 85187-10-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113498.
Sphingomyelin
Sphingomyelin. Group: Biochemicals. Alternative Names: N-Hexadecanoyl-D-sphingosine-1-phosphocholine. Grades: Highly Purified. CAS No. 85187-10-6,383907-87-7,13053-57-1. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C39H79N2O6P. US Biological Life Sciences.
Worldwide
sphingomyelin deacylase
The enzyme is involved in the sphingolipid metabolism in the epidermis. Group: Enzymes. Synonyms: SM deacylase; GcSM deacylase; glucosylceramide sphingomyelin deacylase; sphingomyelin glucosylceramide deacylase; SM glucosylceramide GCer deacylase; SM-GCer deacylase; SMGCer deacylase. Enzyme Commission Number: EC 3.5.1.109. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4388; sphingomyelin deacylase; EC 3.5.1.109; SM deacylase; GcSM deacylase; glucosylceramide sphingomyelin deacylase; sphingomyelin glucosylceramide deacylase; SM glucosylceramide GCer deacylase; SM-GCer deacylase; SMGCer deacylase. Cat No: EXWM-4388.
sphingomyelin phosphodiesterase
Has very little activity on phosphatidylcholine. Group: Enzymes. Synonyms: neutral sphingomyelinase. Enzyme Commission Number: EC 3.1.4.12. CAS No. 9031-54-3. SMase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3712; sphingomyelin phosphodiesterase; EC 3.1.4.12; 9031-54-3; neutral sphingomyelinase. Cat No: EXWM-3712.
sphingomyelin phosphodiesterase D
Does not act on phosphatidylcholine, but hydrolyses 2-lysophosphatidylcholine to choline and 2-lysophosphatidate. Group: Enzymes. Synonyms: sphingomyelinase D. Enzyme Commission Number: EC 3.1.4.41. CAS No. 54992-31-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3725; sphingomyelin phosphodiesterase D; EC 3.1.4.41; 54992-31-3; sphingomyelinase D. Cat No: EXWM-3725.
Sphingomyelins, milk
Sphingomyelins, milk (SMs (buttermilk)) are compounds studied in sphingolipids, which play important roles in various biological processes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SMs (buttermilk). CAS No. 475662-40-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-165136.
sphingomyelin synthase
The reaction can occur in both directions. This enzyme occupies a central position in sphingolipid and glycerophospholipid metabolism. Up- and down-regulation of its activity has been linked to mitogenic and pro-apoptotic signalling in a variety of mammalian cell types. Unlike EC 2.7.8.3, ceramide cholinephosphotransferase, CDP-choline cannot replace phosphatidylcholine as the donor of the phosphocholine moiety of sphingomyelin. Group: Enzymes. Synonyms: SM synthase; SMS1; SMS2. Enzyme Commission Number: EC 2.7.8.27. CAS No. 58703-97-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3326; sphingomyelin synthase; EC 2.7.8.27; 58703-97-2; SM synthase; SMS1; SMS2. Cat No: EXWM-3326.
Sphingosine 1-phosphate
Sphingosine-1-phosphate is an endogenous second messenger that inhibits cell proliferation and motility, and Ca2+ mobilization to prevent tumor cell metastasis. Sphingosine-1-phosphate acts as an agonist at sphingosine-1-phosphate receptors (S1P1-5) and as an activator of GPR3, GPR6 and GPR12. Synonyms: D-erythro-Sphingosine-1-phosphate; C18-Sphingosine 1-phosphate; Sphing-4-enine 1-phosphate; (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate. Grades: ≥98% by HPLC. CAS No. 26993-30-6. Molecular formula: C18H38NO5P. Mole weight: 379.48.
Sphingosine-1-phosphate
Sphingosine-1-phosphate. Group: Biochemicals. Grades: Purified. CAS No. 26993-30-6. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Sphingosine-1-phosphate
Sphingosine-1-phosphate (S1P) is an agonist of S1P 1-5 receptors and a ligand of GPR3, GPR6 and GPR12. Sphingosine-1-phosphate is an intracellular second messenger and mobilizes Ca 2+ as an extracellular ligand for G protein-coupled receptors [1]. Sphingosine-1-phosphate is an important lipid mediator generated from Sphingomyelin (HY-113498) or other membrane phospholipids [2]. Sphingosine-1-phosphate stimulates the DNA synthesis, cell proliferation and migration [4]. Uses: Scientific research. Group: Natural products. Alternative Names: S1P. CAS No. 26993-30-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108496.
Sphingosine-1-phosphate (d16:1)
Sphingosine-1-phosphate (d16:1) is an unsaturated derivative of sphingosine-1-phosphate (S1P) that binds to S1P1/EDG-1, S1P3/EDG-3, and S1P2/EDG-5 receptors. Synonyms: C16 S1P; C16 Sphingosine-1-phosphate; S1P (d16:1); Hexadecasphing-4-enine-1-phosphate; [(E,2S,3R)-2-amino-3-hydroxyhexadec-4-enyl] dihydrogen phosphate. Grades: ≥95%. CAS No. 709026-60-8. Molecular formula: C16H34NO5P. Mole weight: 351.4.
Sphingosine-1-phosphate (d17:1)
Sphingosine-1-phosphate d17:1 (D-erythro-Sphingosine-C17-1-phosphate) is a derivative of ceramide. Sphingosine-1-phosphate d17:1 can be used for the research of cancer [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: D-erythro-Sphingosine-C17-1-phosphate. CAS No. 474923-27-8. Pack Sizes: 1 mg. Product ID: HY-141630.
Sphingosine-1-phosphate-d7
Sphingosine-1-phosphate-d 7 is the deuterium labeled Sphingosine-1-phosphate. Sphingosine-1-phosphate (S1P) is an agonist of S1P1-5 receptors and a ligand of GPR3, GPR6 and GPR12. Sphingosine-1-phosphate is an intracellular second messenger and mobilizes Ca2+ as an extracellular ligand for G protein-coupled receptors[1]. Sphingosine-1-phosphate is an important lipid mediator generated from Sphingomyelin (HY-113498) or other membrane phospholipids[2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: S1P-d7. CAS No. 2260670-15-1. Pack Sizes: 1 mg; 5 mg; 500 μg. Product ID: HY-108496S.
sphingosine β-galactosyltransferase
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. Group: Enzymes. Synonyms: psychosine-UDP galactosyltransferase; galactosyl-sphingosine transferase; psychosine-uridine diphosphate galactosyltransferase; UDP-galactose:sphingosine O-galactosyl transferase; uridine diphosphogalactose-sphingosine β-galactosyltransferase; UDP-galactose:sphingosine 1-β-galactotransferase; UDP-galactose:sphingosine 1-β-galactosyltransferase. Enzyme Commission Number: EC 2.4.1.23. CAS No. 9032-90-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2459; sphingosine β-galactosyltransferase; EC 2.4.1.23; 9032-90-0; psychosine-UDP galactosyltransferase; galactosyl-sphingosine transferase; psychosine-uridine diphosphate galactosyltransferase; UDP-galactose:sphingosine O-galactosyl transferase; uridine diphosphogalactose-sphingosine β-galactosyltransferase; UDP-galactose:sphingosine 1-β-galactotransferase; UDP-galactose:sphingosine 1-β-galactosyltransferase. Cat No: EXWM-2459.
sphingosine cholinephosphotransferase
This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups. This enzyme participates in sphingolipid metabolism. Group: Enzymes. Synonyms: CDP-choline-sphingosine cholinephosphotransferase; phosphorylcholine-sphingosine transferase; cytidine diphosphocholine-sphingosine cholinephosphotransferase; sphingosine choline phosphotransferase. Enzyme Commission Number: EC 2.7.8.10. CAS No. 9027-12-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3310; sphingosine cholinephosphotransferase; EC 2.7.8.10; 9027-12-7; CDP-choline-sphingosine cholinephosphotransferase; phosphorylcholine-sphingosine transferase; cytidine diphosphocholine-sphingosine cholinephosphotransferase; sphingosine choline phosphotransferase. Cat No: EXWM-3310.