A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Sapphire substrate, 10x10x0.432mm, EPI polished one side, C-axis, LED grade
Emery is an odorless, white, crystalline powder. Natural aluminum oxide. Very high melting and hard. Used for polishing, grinding, and abrasive operations. An inhalation hazard when present as a dust.;DryPowder, PelletsLargeCrystals;WHITE POWDER.;Odorless, white, crystalline powder.;Odorless, white, crystalline powder. Molecular formula: Al2O3;Al2O3. Mole weight: 101.961g/mol. IUPAC Name: oxo(oxoalumanyloxy)alumane. SMILES: O=[Al]O[Al]=O. InChI: InChI=1S/2Al.3O.
Sapphire substrate, 10x10x0.432mm, EPI polished two sides, C-axis, LED grade
Sapphire substrate, 10x10x0.432mm, EPI polished two sides, C-axis, LED grade.
Sapphire substrate, 50.8mm dia x 0.332mm thick, EPI polished one side, C-axis, HEMCOR single crystal
Sapphire substrate, 50.8mm dia x 0.332mm thick, EPI polished one side, C-axis, HEMCOR single crystal.
Sapphire substrate, 50.8mm dia x 0.332mm thick, EPI polished two sides, C-axis, HEMCOR single crystal
Sapphire substrate, 50.8mm dia x 0.332mm thick, EPI polished two sides, C-axis, HEMCOR single crystal.
Sapphire substrate, 50.8mm dia x 0.432mm thick, EPI polished one side, C-axis, HEMCOR single crystal
Sapphire substrate, 50.8mm dia x 0.432mm thick, EPI polished one side, C-axis, HEMCOR single crystal.
Sapphire substrate, 50.8mm dia x 0.432mm thick, EPI polished two sides, C-axis, HEMCOR single crystal
Emery is an odorless, white, crystalline powder. Natural aluminum oxide. Very high melting and hard. Used for polishing, grinding, and abrasive operations. An inhalation hazard when present as a dust.;DryPowder, PelletsLargeCrystals;WHITE POWDER.;Odorless, white, crystalline powder.;Odorless, white, crystalline powder. Molecular formula: Al2O3;Al2O3. Mole weight: 101.961g/mol. IUPAC Name: oxo(oxoalumanyloxy)alumane. SMILES: O=[Al]O[Al]=O. InChI: InChI=1S/2Al.3O.
Sapropterin
It has a role as a coenzyme, a diagnostic agent, a human metabolite and a cofactor. Category: Active pharmaceutical ingredients. Synonyms: tetrahydrobiopterin. R-THBP. Dapropterin. CAS No. 62989-33-7. Product ID: API62989337. Molecular formula: C9H15N5O3. Mole weight: 241.25. EINECS: 636-312-4. SMILES: CC(C(C1CNC2=C(N1)C(=O)NC(=N2)N)O)O. Appearance: Solid.
Sapropterin-[d3]
A deuterated Sapropterin. Sapropterin is a cofactor for phenylalanine hydroxylase. Synonyms: (R)-2-amino-6-((1R,2S)-1,2-dihydroxypropyl)-5,6,7,8-tetrahydropteridin-4(3H)-one-D3. Grade: >95%. Molecular formula: C9H12D3N5O3. Mole weight: 244.27.
Sapropterin dihydrochloride
Sapropterin ((6R)-BH4; (6R)-Tetrahydro-L-biopterin) dihydrochloride is an orally active phenylalanine hydroxylase (PAH) cofactor, which is effective in reducing blood phenylalanine concentrations. Sapropterin dihydrochloride can be used in study of phenylketonuria (PKU) phenylketonuria. Sapropterin dihydrochloride can aggravate experimental autoimmune encephalomyelitis (EAE)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (6R)-BH4 dihydrochloride; (6R)-Tetrahydro-L-biopterin dihydrochloride. CAS No. 69056-38-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0124A.
Sapropterin Dihydrochloride
Tetrahydrobiopterin (BH4, THB), also known as sapropterin, is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin (5-hydroxytryptamine, 5-HT), melatonin, dopamine, norepinephrine (noradrenaline), epinephrine (adrenaline), and is a cofactor for the production of nitric oxide (NO) by the nitric oxide synthases.[1] Chemically, its structure is that of a reduced pteridine derivative. Group: Biochemicals. Alternative Names: (6R)-5,6,7,8-Tetrahydrobiopterin dihydrochloride; 6R-BH4. CAS No. 17528-72-2. Pack Sizes: 50mg, 100mg, 250mg. US Biological Life Sciences.
Worldwide
SAP (Sodium Ascorbyl Phosphate)
SAP (Sodium Ascorbyl Phosphate). Alternative Names: L-Ascorbic acid-2-monophosphate, trisodium salt. CAS No. 66170-10-3. Product ID: CI-HC-0350. Molecular formula: C6H6O9P.Na. Mole weight: 322.05 g/mol. ECNumber: 425-180-1. Alfa Chemistry - ISO 9001:32057 Certified.
Sapurimycin
It is produced by the strain of Str. sp. DO-116. It has anti-gram-positive bacteria effect. In vivo, it has the effect of anti-leukemia P388 and sarcoma 180 cells. Determination in vitro, it has the effect of causing single strand breaks in superhelical plasmid DNA. Synonyms: Antibiotic DC 116; 4H-Anthra(1,2-b)pyran-5-acetic acid, 7,12-dihydro-8,11-dihydroxy-2-(2-methyl-3-(1-propenyl)oxiranyl)-4,7,12-trioxo-, (2-alpha,3-alpha(Z))-(+)-. CAS No. 133021-37-1. Molecular formula: C25H18O9. Mole weight: 462.40.
Saquayamycin A
It is produced by the strain of Str. nodosus MH190-16F3. It has antimicrobial effect, but it has weaker effect against gram-negative bacteria. It has inhibitory effect on leukemia P388 cells and adriamycin-resistant P388 cells. Synonyms: saquayamycin; Benz[a]anthracene-1,7,12(2H)-trione, 9-[2,6-dideoxy-4-O-[(2R,6S)-5,6-dihydro-6-methyl-5-oxo-2H-pyran-2-yl]-b-D-arabino-hexopyranosyl]-3-[[(2S,5S,6S)-5-[[(2R,6S)-5,6-dihydro-6-methyl-5-oxo-2H-pyran-2-yl]oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-3,4,4a,12b-tetrahydro-4a,8,12b-trihydroxy-3-methyl-, (3R,4aR,12bS)-; Benz[a]anthracene-1,7,12(2H)-trione, 9-[2,6-dideoxy-4-O-[(2R-trans)-5,6-dihydro-6-methyl-5-oxo-2H-pyran-2-yl]-b-D-arabino-hexopyranosyl]-3-[[5-[(5,6-dihydro-6-methyl-5-oxo-2H-pyran-2-yl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-3,4,4a,12b-tetrahydro-4a,8,12b-trihydroxy-3-methyl-,[2S-[2a(3S*,4aS*,12bR*),5b(2S*,6R*),6b]]-. CAS No. 99260-65-8. Molecular formula: C43H48O16. Mole weight: 820.83.
Saquayamycin A1
It is produced by the strain of Str. nodosus MH190-16F3. It has antimicrobial effect, but it has weaker effect against gram-negative bacteria. It has inhibitory effect on leukemia P388 cells and adriamycin-resistant P388 cells. Synonyms: Benz[a]anthracene-1,7,12(2H)-trione, 9-[2,6-dideoxy-4-O-[(2R,6S)-5,6-dihydro-6-methyl-5-oxo-2H-pyran-2-yl]- -Darabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-3,4a,8,12b-tetrahydroxy-3-methyl-, (3R,4aR,12bS)-; (3R)-9-[4-O-[(2R,6S)-5,6-Dihydro-6-methyl-5-oxo-2H-pyran-2-yl]-2,6-dideoxy-β-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-3α,4aα,8,12bα-tetrahydroxy-3-methylbenz[a]anthracene-1,7,12(2H)-trione. Grade: 95%. CAS No. 99260-66-9. Molecular formula: C31H32O12. Mole weight: 596.58.
Saquayamycin B
It is produced by the strain of Str. nodosus MH190-16F3. It has antimicrobial effect, but it has weaker effect against gram-negative bacteria. It has inhibitory effect on leukemia P388 cells and adriamycin-resistant P388 cells. Synonyms: Benz[a]anthracene-1,7,12(2H)-trione, 9-[[2',3-anhydro]-2,6-dideoxy-4-O-(3,6-dideoxy-a-L-erythro-hexopyranos-4-ulos-1-yl)-b-D-arabino-hexopyranosyl]-3-[[(2S,5S,6S)-5-[[(2R,6S)-5,6-dihydro-6-methyl-5-oxo-2H-pyran-2-yl]oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-3,4,4a,12b-tetrahydro-4a,8,12b-trihydroxy-3-methyl-, (3R,4aR,12bS)-; Benz[a]anthracene-1,7,12(2H)-trione, 9-[[2',3-anhydro]-2,6-dideoxy-4-O-(3,6-dideoxy-a-L-erythro-hexopyranos-4-ulos-1-yl)-b-D-arabino-hexopyranosyl]-3-[[5-[(5,6-dihydro-6-methyl-5-oxo-2H-pyran-2-yl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-3,4,4a,12b-tetrahydro-4a,8,12b-trihydroxy-3-methyl-, [2S-[2a(3S*,4aS*,12bR*),5b(2S*,6R*),6b]]-. CAS No. 99260-67-0. Molecular formula: C43H48O16. Mole weight: 820.83.
Saquayamycin B1
It is produced by the strain of Str. nodosus MH190-16F3. It has antimicrobial effect, but it has weaker effect against gram-negative bacteria. It has inhibitory effect on leukemia P388 cells and adriamycin-resistant P388 cells. Synonyms: Benz[a]anthracene-1,7,12(2H)-trione, 9-[[2',3-anhydro]-2,6-dideoxy-4-O-(3,6-dideoxy-RL-erythro-hexopyranos-4-ulos-1-yl)-a-Darabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-3,4a,8,12b-tetrahydroxy-3-methyl-, (3R,4aR,12bS)-. Grade: ≥95%. CAS No. 99260-68-1. Molecular formula: C31H32O12. Mole weight: 596.58.
Saquayamycin B1
Angucycline antibiotic. Antibacterial. Antitumor compound. Active against Gram-positive bacteria and P388 leukemia cells. Farnesyl-protein transferase inhibitor. Inhibitor of nitric oxide synthase (NOS) (shown for Saquayamycin A1). Group: Biochemicals. Alternative Names: 9- (2, 9-dimethyl-3-oxo-4, 4a, 5a, 6, 7, 9, 9a, 10a-octahydrodipyrano [4, 2-a: 4', 3'-e] [1, 4]dioxin-7-yl) -3, 4a, 8, 12b-tetrahydroxy-3-methyl-2, 4-dihydrobenzo [a]anthracene-1, 7, 12-trione. Grades: Highly Purified. CAS No. 99260-68-1. Pack Sizes: 500ug, 1mg. US Biological Life Sciences.
Worldwide
Saquayamycin C
It is produced by the strain of Str. nodosus MH190-16F3. It has antimicrobial effect, but it has weaker effect against gram-negative bacteria. It has inhibitory effect on leukemia P388 cells and adriamycin-resistant P388 cells. Synonyms: Benz[a]anthracene-1,7,12(2H)-trione, 9-[2,6-dideoxy-4-O-[(2R,6S)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]-b-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-4a,8,12b-trihydroxy-3-methyl-3-[[(2S,5S,6S)-tetrahydro-6-methyl-5-[[(2R,6S)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]oxy]-2H-pyran-2-yl]oxy]-, (3R,4aR,12bS)-; Benz[a]anthracene-1,7,12(2H)-trione, 9-[2,6-dideoxy-4-O-[(2R-trans)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]-b-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-4a,8,12b-trihydroxy-3-methyl-3-[[tetrahydro-6-methyl-5-[(tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl)oxy]-2H-pyran-2-yl]oxy]-, [2S-[2a(3S*,4aS*,12bR*),5b(2S*,6R*),6b]]-. CAS No. 99260-70-5. Molecular formula: C43H52O16. Mole weight: 824.86.
Saquayamycin C1
It is produced by the strain of Str. nodosus MH190-16F3. It has antimicrobial effect, but it has weaker effect against gram-negative bacteria. It has inhibitory effect on leukemia P388 cells and adriamycin-resistant P388 cells. Synonyms: (3R)-9-[4-O-[(2R,6S)-Tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]-2,6-dideoxy-β-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-3α,4aα,8,12bα-tetrahydroxy-3-methylbenz[a]anthracene-1,7,12(2H)-trione. CAS No. 99260-69-2. Molecular formula: C31H34O12. Mole weight: 598.59.
Saquayamycin D
It is produced by the strain of Str. nodosus MH190-16F3. It has antimicrobial effect, but it has weaker effect against gram-negative bacteria. It has inhibitory effect on leukemia P388 cells and adriamycin-resistant P388 cells. Synonyms: Benz[a]anthracene-1,7,12(2H)-trione, 9-[[2',3-anhydro]-2,6-dideoxy-4-O-(3,6-dideoxy-a-L-erythro-hexopyranos-4-ulos-1-yl)-b-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-4a,8,12b-trihydroxy-3-methyl-3-[[(2S,5S,6S)-tetrahydro-6-methyl-5-[[(2R,6S)-tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl]oxy]-2H-pyran-2-yl]oxy]-, (3R,4aR,12bS)-; Benz[a]anthracene-1,7,12(2H)-trione, 9-[[2',3-anhydro]-2,6-dideoxy-4-O-(3,6-dideoxy-a-L-erythro-hexopyranos-4-ulos-1-yl)-b-D-arabino-hexopyranosyl]-3,4,4a,12b-tetrahydro-4a,8,12b-trihydroxy-3-methyl-3-[[tetrahydro-6-methyl-5-[(tetrahydro-6-methyl-5-oxo-2H-pyran-2-yl)oxy]-2H-pyran-2-yl]oxy]-, [2S-[2a(3S*,4aS*,12bR*),5b(2S*,6R*),6b]]-. CAS No. 99260-71-6. Molecular formula: C43H50O16. Mole weight: 822.85.
Saquinavir
Saquinavir (Ro 31-8959) is an orally active HIV protease inhibitor that can be used in the research of AIDS. Saquinavir also has anti-inflammatory activity and can induce apoptosis of human red blood cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro 31-8959. CAS No. 127779-20-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17007.
Saquinavir
Saquinavir(Ro 31-8959) is an HIV Protease inhibitor used in antiretroviral therapy. HIV protease is vital for both viral replication within the cell and release of mature viral particles from an infected cell. Saquinavir binds to the active site of the viral protease and prevents cleavage of viral polyproteins, preventing maturation of the virus. Saquinavir inhibits both HIV-1 and HIV-2 proteases. Studies have also looked at Saquinavir as a possible anti-cancer agent. Group: Biochemicals. Alternative Names: Saquinavir; Ro 31-8959; (2S) -N- [ (2S, 3R) -4- [ (3S, 4aS, 8aS) -3- (tert-butylcarbamoyl) -decahydroisoquinolin-2-yl] -3-hydroxy-1-phenylbutan-2-yl] -2- [ (quinolin-2-yl) formamido] butanediamide. Grades: Highly Purified. CAS No. 127779-20-8. Pack Sizes: 250mg, 500mg, 1g. Molecular Formula: C38H50N6O5, Molecular Weight: 670.84. US Biological Life Sciences.
Worldwide
Saquinavir
Saquinavir was the first protease inhibitor approved for the treatment of HIV infection, introduced in 1995 as a breakthrough therapy. The drug is chemically a peptidomimetic that mimics the transition state of the viral protease substrate. Applications: Saquinavir is indicated in combination with ritonavir (as a pharmacokinetic booster) and other antiretrovirals for the treatment of hiv-1 infection. ritonavir dramatically increases saquinavir exposure by inhibiting cyp3a4 metabolism. due to its high pill burden and gastrointestinal side effects, it is no longer a first-line agent, though it remains a valuable option for treatment-experienced patients with resistance to newer protease inhibitors. Category: Active pharmaceutical ingredients. Synonyms: Fortovase; Saquinavirum; L3JE09KZ2F; CHEBI:63621; SCH-52852; DTXSID6044012. CAS No. 127779-20-8. Product ID: API0231588. Molecular formula: C38H50N6O5. Mole weight: 670.8. InChIKey: QWAXKHKRTORLEM-UGJKXSETSA-N. Appearance: White to off-white powder.
Saquinavir-[d6]
A deuterated squinavir. Saquinavir binds to the active site of the viral protease and prevents cleavage of viral polyproteins, preventing maturation of the virus. Saquinavir inhibits both HIV-1 and HIV-2 proteases. Synonyms: (2S)-N1[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]octahydro-2-(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]butanediamide-d6; Fortovase-d6; Invirase-d6; Ro 31-8959-d6. Grade: >95%. Molecular formula: C38H44D6N6O5. Mole weight: 676.90.
Saquinavir-d9
Labeled Saquinavir. A selective HIV protease inhibitor. Antiviral. Group: Biochemicals. Alternative Names: (2S) -N1 [ (1S, 2R) -3- [ (3S, 4aS, 8aS) -3- [ [ (1, 1-Dimethylethyl) amino] carbonyl] octahydro-2- (1H) -isoquinolinyl] -2-hydroxy-1- (phenylmethyl) propyl] -2- [ (2-quinolinylcarbonyl) amino] butanediamide-d9; Fortovase-d9; Invirase-d9; Ro 31-8959-d9. Grades: Highly Purified. CAS No. 1356355-11-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Saquinavir-[d9]
A deuterated squinavir. Saquinavir binds to the active site of the viral protease and prevents cleavage of viral polyproteins, preventing maturation of the virus. Saquinavir inhibits both HIV-1 and HIV-2 proteases. Synonyms: (2S)-N1[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-Dimethylethyl)amino]carbonyl]octahydro-2-(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]butanediamide-d9; Fortovase-d9; Invirase-d9; Ro 31-8959-d9. Grade: >98%. CAS No. 1356355-11-7. Molecular formula: C38H41D9N6O5. Mole weight: 679.91.
Saquinavir mesylate
Saquinavir mesylate. Group: Biochemicals. Grades: Purified. CAS No. 149845-06-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Saquinavir mesylate
Saquinavir (Ro 31-8959) mesylate is an orally active HIV protease inhibitor that can be used in the research of AIDS. Saquinavir mesylate also has anti-inflammatory activity and can induce apoptosis of human red blood cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro 31-8959/003. CAS No. 149845-06-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17003.
SAR131675
SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells. SAR131675 also dose dependently inhibited the proliferation of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD. Group: Biochemicals. Alternative Names: 2-Amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl)-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide; 2-Amino-1-ethyl-1,4-dihydro-7-(3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl)-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide. Grades: Highly Purified. CAS No. 1092538-80-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C??H??N?O?, Molecular Weight: 358.39. US Biological Life Sciences.
Worldwide
SAR131675
SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM. SAR131675 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1433953-83-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15458.
SAR247799
SAR247799 (S1P1 agonist 3) is an oral activity, selective G-protein-biased sphingosine-1 phosphate receptor-1 (S1P1 ) agonist, with EC50s rang from 12.6 to 493 nM in S1P1-overexpressing cells and HUVECs. SAR247799 can be used for the research of endothelial protection, including type-2 diabetes, metabolic syndrome[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S1P1 agonist 3. CAS No. 1315311-14-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115831.
SAR405
SAR405 is a low-molecular-mass kinase inhibitor of PIK3C3/Vps34 (KD 1.5 nM) showing high selectivity and not be active up to 10 μM on class I and class II PI3Ks as well as on mTOR. SAR405 prevents autophagy and synergizes with MTOR (mechanistic target of rapamycin) inhibition in tumor cells. Group: Inhibitors. CAS No. 1523406-39-4. Pack Sizes: 5mg. Product ID: S7682. Formula: C19H21ClF3N5O2. Smiles: CC1COCCN1C2=CC(=O)N3CCC(N(C3=N2)CC4=CC(=CN=C4)Cl)C(F)(F)F. Storage Conditions: 2 years -80 in solvent.
United States; Europe
SAR405
SAR405 is a first-in-class, selective, and ATP-competitive PI3K class III (PIK3C3) isoform Vps34 inhibitor (IC50=1.2 nM; Kd=1.5 nM). SAR405 inhibits autophagy induced either by starvation or by mTOR inhibition. Anticancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1523406-39-4. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12481.
SAR407899
SAR407899 is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively. SAR407899 shows stable inhibition of migrasome formation. Uses: Scientific research. Category: Signaling pathways. CAS No. 923359-38-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15687A.
SAR441255
SAR441255 is a synthetic peptide agonist of the GLP-1, GCG, and GIP receptors. SAR441255 showed substantial body weight loss and improved glucose control in diabetic obese monkeys. Synonyms: H-Aib-HGTFTSDLSKL-K(γGlu-γGlu-Palm acid)-EEQRQ-AibEFIEWLKA-dAla-GPPS-Aib-KPPPK-NH2. Molecular formula: C206H323N51O66. Mole weight: 4570.06.
SAR502250
SAR502250 is a potent, selective, ATP competitive, orally active and brain-penetrant inhibitor of GSK3, with an IC50 of 12 nM for human GSK-3β. SAR502250 displays antidepressant-like activity. SAR502250 can be used for the research of Alzheimers disease (AD)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 503860-57-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137472.
SAR629
SAR629 is a potent monoglyceride lipase (MGL) covalent inhibitor. SAR629 also inhibits 2-Arachidonoylglycerol (2-AG) degradation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1221418-42-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118653.
SAR7334
SAR7334 is a potent and specific TRPC6 inhibitor, inhibiting TRPC6 currents with IC50 of 7.9 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1333210-07-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15699.
SAR7334 hydrochloride
SAR7334 hydrochloride is a potent and specific TRPC6 inhibitor, inhibiting TRPC6 currents with IC50 of 7.9 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1333207-63-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15699A.
Saracatinib
Saracatinib (AZD0530) is a potent Src family inhibitor with IC50s of 2.7 to 11 nM for c-Src, Lck, c-YES, Lyn, Fyn, Fgr, and Blk. Saracatinib shows high selectivity over other tyrosine kinases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD0530. CAS No. 379231-04-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10234.
Saracatinib
An oral, selective dual inhibitor of Src and ABL kinase. Group: Biochemicals. Alternative Names: N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine; 7- [2- [4-Methylpiperazin-1-yl] ethoxy] -5- [ [tetrahydropyran-4-yl] oxy] -4- [ [6-chloro-2, 3-methylenedioxyphenyl] amino] quinazoline. Grades: Highly Purified. CAS No. 379231-04-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg. US Biological Life Sciences.
Worldwide
Saracatinib (AZD0530)
Saracatinib (AZD0530) is a potent Src inhibitor with IC50 of 2.7 nM in cell-free assays, and potent to c-Yes, Fyn, Lyn, Blk, Fgr and Lck; less active for Abl and EGFR (L858R and L861Q). Saracatinib induces autophagy. Phase 2/3. Group: Inhibitors. CAS No. 379231-04-6. Pack Sizes: 10mg. Product ID: S1006. Formula: C27H32ClN5O5. Smiles: CN1CCN(CC1)CCOC2=CC3=C(C(=C2)OC4CCOCC4)C(=NC=N3)NC5=C(C=CC6=C5OCO6)Cl. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Saracatinib difumarate
Saracatinib (AZD0530) difumarate is a potent Src inhibitor with IC50 values of 2.7-11 nM for c-Src, Lck, c-YES, Lyn, Fyn, Fgr and Blk, and is selective for other tyrosine kinases. [1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD0530 difumarate. CAS No. 893428-72-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10234A.
Sarafloxacin
Sarafloxacin. Group: Biochemicals. Grades: Highly Purified. CAS No. 98105-99-8. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C20H17F2N3O3. US Biological Life Sciences.
A Fluorinated quinolone antibacterial. Group: Biochemicals. Alternative Names: 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Sarafloxacin-[d8] Hydrochloride
Sarafloxacin-[d8] Hydrochloride is the labelled hydrochloride form of Sarafloxacin. Sarafloxacin is a quinolone antibiotic drug, inhibiting the topoisomerase II ligase domain. Synonyms: 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl-d8)-3-quinolinecarboxylic Acid Hydrochloride; A 56620-d8; PD 121960-d8; Sarafin-d8. Grade: >98%. CAS No. 1352879-52-7. Molecular formula: C20H10D8ClF2N3O3. Mole weight: 429.87.
Sarafloxacin-[d8] hydrochloride hydrate
Sarafloxacin-[d8] hydrochloride hydrate is a labelled analogue of Sarafloxacin. Sarafloxacin is a topoisomerase II ligase inhibitor used as a quinolone antibiotic drug. Synonyms: Sarafloxacin-D8 hydrochloride hydrate; Difloxacino-d8 hydrochloride hydrate; Difloxacinum-d8 hydrochloride hydrate; Sarafloxacino-d8 hydrochloride hydrate; Sarafloxacinum-d8 hydrochloride hydrate; 6-Fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazine-D8-1-yl-1,4-dihydroquinoline-3-carboxylic acid hydrochloride hydrate. Grade: 95% by HPLC; 98% atom D. Molecular formula: C20H9D8F2N3O3.HCl.H2O. Mole weight: 447.87.
Sarafloxacin hydrochloride
Sarafloxacin hydrochloride (A-56620 hydrochloride) is a fluoroquinolone Antibacterial agent. Sarafloxacin inhibits the growth of Staphylococcus aureus, Enterobacteriaceae, and both aminoglycoside-sensitive and aminoglycoside-resistant strains of Pseudomonas aeruginosa[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: A-56620 hydrochloride. CAS No. 91296-87-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0343A.
Sarafloxacin hydrochloride
Sarafloxacin is a quinolone antibiotic drug, inhibiting the topoisomerase II ligase domain. It inhibits bacterial Topo II α (DNA gyrase, topoisomerase) and is effective against Mycobacterium tuberculosis. Synonyms: Sarafloxacin HCl; A-56620; A 56620; A56620. Grade: >98%. CAS No. 91296-87-6. Molecular formula: C20H17F2N3O3.HCl. Mole weight: 421.83.
Sarafloxacin hydrochloride
Sarafloxacin hydrochloride. Group: Biochemicals. Alternative Names: 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride; A 56620; PD 121960. Grades: Highly Purified. CAS No. 91296-87-6. Pack Sizes: 500mg, 1g, 2g, 5g. Molecular Formula: C20H18ClF2N3O3. US Biological Life Sciences.
Worldwide
Sarafotoxin S6a
Sarafotoxin S6a. Group: Biochemicals. Grades: Purified. CAS No. 126738-34-9. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
Sarafotoxin S6b
Sarafotoxins (SRTXs) are group of toxins present in a venom of Atractaspis engaddensis, and in clinical trials cause similar symptoms to patients diagnosed with acute giardiasis.[1] Together with endothelins (ETs), they form a homogenous family of strong vasoconstrictor isopeptides. Among them, few slightly different substances can be named, as SRTX-a, SRTX-b, SRTX-c, which were initially derived from Atractaspis engaddensis. Each contains twenty-one amino acid residues that spontaneously fold into a defined tertiary structure with two interchain-cysteine linkages (disulfide bonds) and a long hydrophobic tail.[2] There are also other compounds, however, they are mostly derivations of previously mentioned ones. The main differences in the family of endothelin and sarafotoxins appear at N-terminal of peptides, as C-terminal in all of them is almost the same.[3]. Group: Biochemicals. Grades: Purified. CAS No. 116303-65-2. Pack Sizes: 100ug. Molecular Formula: C110H159N27O34S5, Molecular Weight: 2564. US Biological Life Sciences.
Worldwide
Sarafotoxin S6c
Sarafotoxin S6c. Group: Biochemicals. Grades: Purified. CAS No. 121695-87-2. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
Sarafotoxin S6c
Sarafotoxin S6c is a highly selective ETB endothelin receptor agonist (Ki = 0.29 and 28000 nM at ETB and ETA receptors, respectively). Uses: Vasoconstrictor agents. Synonyms: Sarafotoxin C; S6C; H-Cys-Thr-Cys-Asn-Asp-Met-Thr-Asp-Glu-Glu-Cys-Leu-Asn-Phe-Cys-His-Gln-Asp-Val-Ile-Trp-OH (Disulfide bridge: Cys1-Cys15, Cys3-Cys11); L-cysteinyl-L-threonyl-L-cysteinyl-L-asparagyl-L-alpha-aspartyl-L-methionyl-L-threonyl-L-alpha-aspartyl-L-alpha-glutamyl-L-alpha-glutamyl-L-cysteinyl-L-leucyl-L-asparagyl-L-phenylalanyl-L-cysteinyl-L-histidyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-isoleucyl-L-tryptophan (1->15),(3->11)-bis(disulfide). Grade: ≥95% by HPLC. CAS No. 121695-87-2. Molecular formula: C103H147N27O37S5. Mole weight: 2515.75.
Saralasin
Saralasin is a competitive and nonselective angiotensin II receptor antagonist. Uses: Angiotensin ii type 1 receptor blockers. Synonyms: (Sar1,Val5,Ala8)-Angiotensin II; Aralasin; Saralasinum. Grade: ≥97% by HPLC. CAS No. 34273-10-4. Molecular formula: C42H65N13O10. Mole weight: 912.04.
Saralasin
Saralasin. Group: Biochemicals. Grades: Purified. CAS No. 34273-10-4. Pack Sizes: 5mg. US Biological Life Sciences.
Sarcosine is an endogenous GlyT1 inhibitor. Sarcosine displays antipsychotic activity and has the potential to treat schizophrenia. Sarcosine has been shown to potentiate the action of glycine on the NMDA glycine binding site. Uses: Sarcosine, also known as n-methylglycine, is a naturally occurring amino acid derivative that has shown promise in various areas including drug discovery and development. in recent years, there has been growing interest in exploring the pharmacological properties of sarcosine and its derivatives due to their diverse biological activities. sarcosine is a basic derivative of amino acids that is ess. Synonyms: N-Methylglycine; Sarcosinic acid; Methylglycine; Glycine, N-methyl-. Grade: 98%. CAS No. 107-97-1. Molecular formula: C3H7NO2. Mole weight: 89.09.
Sarcosine
500g Pack Size. Group: Amino Acids, Biochemicals, Organics, Peptide Reagents. Formula: C3H7NO2. CAS No. 107-97-1. Prepack ID 38645048-500g. Molecular Weight 89.09. See USA prepack pricing.
Sarcosine
100g Pack Size. Group: Amino Acids, Biochemicals, Organics, Peptide Reagents. Formula: C3H7NO2. CAS No. 107-97-1. Prepack ID 38645048-100g. Molecular Weight 89.09. See USA prepack pricing.
Sarcosine-13C
Sarcosine-13C is an isotope labelled compound of Sarcosine (S140500). Sarcosine is a type 1 glycine transporter inhibitor and a glycine agonist that may be useful for treating schizophrenia. Also, used in the study of the potential therapeutic efficacy of glycine transporter 1 inhibitors in the treatment of central nervous system disorders in human system. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C213CH7NO2, Molecular Weight: 90.09. US Biological Life Sciences.
Worldwide
Sarcosine-13C3
Sarcosine-13C3 is a labelled analogue of Sarcosine (S140500), a type 1 glycine transporter inhibitor and a glycine agonist that may be useful for treating schizophrenia (1). Sarcosine is also a marker for prostate cancer bioagression (2). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: 13C3H7NO2. US Biological Life Sciences.
Worldwide
Sarcosine-[13C3,15N] HCl
Sarcosine-[13C3,15N] HCl is a labelled salt of Sarcosine. Sarcosine is an intermediate of choline metabolism. Synonyms: N-methylglycine-13C3,15N HCl. Grade: 98% by HPLC; 99% atom 13C, 98% atom 15N. Molecular formula: [13C]3H8Cl[15N]O2. Mole weight: 129.53.
Sarcosine 99+%
Sarcosine, also known as N-methylglycine, is an intermediate and byproduct in glycine synthesis and degradation. Sarcosine is metabolized to glycine by the enzyme sarcosine dehydrogenase, while glycine-N-methyl transferase generates sarcosine from glycine. Sarcosine is a natural amino acid found in muscles and other body tissues. In the laboratory, it may be synthesized from chloroacetic acid and methylamine. Sarcosine is found naturally as an intermediate in the metabolism of choline to glycine. Sarcosine is sweet to the taste and dissolves in water. It is used in manufacturing biodegradable surfactants and toothpastes as well as in other applications. Group: Biochemicals. Alternative Names: Sar-OH; N-Methylglycine. Grades: Reagent Grade. CAS No. 107-97-1. Pack Sizes: 25g, 100g, 250g, 1Kg, 2.5Kg. US Biological Life Sciences.
Worldwide
Sarcosine amide hydrochloride
Sarcosine amide hydrochloride. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.