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| Product | Description | |
|---|---|---|
| Saxagliptin Impurity 58 | Saxagliptin Impurity 58. Uses: For analytical and research use. CAS No. 178172-26-4. Molecular formula: C12H19NO4. Mole weight: 241.29. Catalog: APB178172264. |  |
| Saxagliptin Impurity 59 | Saxagliptin Impurity 59. Uses: For analytical and research use. CAS No. 1091626-35-5. Molecular formula: C12H19NO4. Mole weight: 241.29. Catalog: APB1091626355. | |
| Saxagliptin Impurity 60 | Saxagliptin Impurity 60. Uses: For analytical and research use. CAS No. 1359829-04-1. Molecular formula: C12H19NO4. Mole weight: 241.29. Catalog: APB1359829041. | |
| Saxagliptin Impurity 61 | Saxagliptin Impurity 61. Uses: For analytical and research use. Molecular formula: C20H27NO3. Mole weight: 329.44. Catalog: APB09783. | |
| Saxagliptin Impurity 62 | Saxagliptin Impurity 62. Uses: For analytical and research use. CAS No. 361441-97-6. Molecular formula: C17H27NO4. Mole weight: 309.41. Catalog: APB361441976. | |
| Saxagliptin Impurity 63 | Saxagliptin Impurity 63. Uses: For analytical and research use. CAS No. 102502-64-7. Molecular formula: C12H20ClNO2. Mole weight: 245.75. Catalog: APB102502647. | |
| Saxagliptin Impurity 64 | Saxagliptin Impurity 64. Uses: For analytical and research use. CAS No. 2173146-31-9. Molecular formula: C17H25NO5. Mole weight: 323.39. Catalog: APB2173146319. | |
| Saxagliptin Impurity 65 | Saxagliptin Impurity 65. Uses: For analytical and research use. CAS No. 1058660-48-2. Molecular formula: C12H19NO3. Mole weight: 225.29. Catalog: APB1058660482. | |
| Saxagliptin Impurity 66 | Saxagliptin Impurity 66. Uses: For analytical and research use. CAS No. 361440-68-8. Molecular formula: C6H10N2O. Mole weight: 126.16. Catalog: APB361440688. | |
| Saxagliptin Impurity 67 | Saxagliptin Impurity 67. Uses: For analytical and research use. CAS No. 709031-39-0. Molecular formula: C6H11ClN2O. Mole weight: 162.62. Catalog: APB709031390. | |
| Saxagliptin Impurity 68 | Saxagliptin Impurity 68. Uses: For analytical and research use. CAS No. 709031-43-6. Molecular formula: C23H33N3O4. Mole weight: 415.53. Catalog: APB709031436. | |
| Saxagliptin Impurity 69 | Saxagliptin Impurity 69. Uses: For analytical and research use. Molecular formula: C18H26N2O4. Mole weight: 334.42. Catalog: APB09784. | |
| Saxagliptin Impurity 7 | Saxagliptin Impurity 7. Uses: For analytical and research use. Molecular formula: C18H25N3O3. Mole weight: 331.42. Catalog: APB09768. | |
| Saxagliptin Impurity 70 | Saxagliptin Impurity 70. Uses: For analytical and research use. Molecular formula: C18H27N3O3. Mole weight: 333.43. Catalog: APB09785. | |
| Saxagliptin Impurity 71 | Saxagliptin Impurity 71. Uses: For analytical and research use. Molecular formula: C18H24N2O3. Mole weight: 316.4. Catalog: APB09786. | |
| Saxagliptin Impurity 72 | Saxagliptin Impurity 72. Uses: For analytical and research use. Molecular formula: C18H25N3O2. Mole weight: 315.42. Catalog: APB09787. | |
| Saxagliptin Impurity 73 | Saxagliptin Impurity 73. Uses: For analytical and research use. Molecular formula: C18H26ClN3O2. Mole weight: 351.88. Catalog: APB09789. | |
| Saxagliptin Impurity 8 | Saxagliptin Impurity 8. Uses: For analytical and research use. CAS No. 841302-24-7. Molecular formula: C18H25N3O3. Mole weight: 331.42. Catalog: APB841302247. | |
| Saxagliptin Impurity 9 | Saxagliptin Impurity 9. Uses: For analytical and research use. Molecular formula: C1713CH24D2ClN3O2. Mole weight: 354.88. Catalog: APB09769. | |
| Saxagliptin O- β-D-glucuronide | Saxagliptin O- β-D-glucuronide. Group: Biochemicals. Alternative Names: (2S,3S,5R,6S)-6-(((1R,3S,5R,7S)-3-((S)-1-Amino-2-((1S,3S,5S)-3-cyano-2-azabicyclo[3.1.0]hexan-2-yl)-2-oxoethyl)adamantan-1-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid. Grades: Highly Purified. CAS No. 1155849-58-3. Pack Sizes: 500ug. Molecular Formula: C24H33N3O8, Molecular Weight: 491.53. US Biological Life Sciences. |  Worldwide |
| Sazetidine A Dihydrochloride | Sazetidine A Hydrochloride is an α4 β2 nicotinic receptor desensitizing agent that exhibits analgesic properties. Sazetidine A Hydrochloride may be used to develop treatments and therapies that aid smoking cessation. Group: Biochemicals. Alternative Names: 6-[5-[(2S)-2-Azetidinylmethoxy]-3-pyridinyl]-5-hexyn-1-ol dihydrochloride. Grades: Highly Purified. CAS No. 1197329-42-2. Pack Sizes: 5mg, 10mg. Molecular Formula: C??H??ClN?O?, Molecular Weight: 333.25. US Biological Life Sciences. | Worldwide |
| SB02024 | SB02024 is a potent and orally active VPS34 inhibitor. SB02024 inhibits Vps34 kinase activity. SB02024 induces CCL5 and CXCL10 via STAT1/IRF7. SB02024 shows anticancer activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2126737-28-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122891. |  |
| SB1-G-187 | SB1-G-187 is a multi-target kinase PROTAC degrader with activity against various kinases including GCK, YES1, IRAK1 and LYN. SB1-G-187 induces degradation of target kinases via a p97-dependent pathway, and forms ternary complexes with CRBN and specific functional kinases. SB1-G-187 can be used in tumor-related research. (Pink: multi-target kinase ligand (HY-125142); Blue: CRBN ligand (HY-A0003); Black: linker)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2769753-18-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137342. | |
| SB-200646A | SB-200646A is the first selective 5-HT2B/2C over 5-HT2A receptor antagonist with pKi values of 7.5, 6.9 and 5.2 for 5-HT2B, 5-HT2C and 5-HT2A, respectively. SB-200646A is orally active and has electrophysiological and anxiolytic properties in vivo[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 143797-62-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103129. | |
| Sb 200646 hydrochloride | Sb 200646 hydrochloride. Alternative Names: SB 200646 hydrochloride, SB-200646 hydrochloride, 143797-62-0, N-(1-Methyl-1H-indol-5-yl)-N-3-pyridinylurea, AC1NSKLO, SB200646, CHEMBL536255, SCHEMBL2116886, CTK8F0080, MolPort-023-276-082, AKOS024456555, SB-200646A, KB-303005, RT-015637, 1-(1-methylindol-5-yl)-3-pyridin-3-ylurea hydrochloride. CAS No. 143797-62-0. Purity: 96%. Product ID: ACM143797620. Molecular formula: C15H14N4O??·HCl??·0.5H2O. Mole weight: 311.77. IUPAC Name: 1-(1-methylindol-5-yl)-3-pyridin-3-ylurea;hydrochloride. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Sb 200646 hydrochloride | Sb 200646 hydrochloride. CAS No. 143797-63-1. Purity: >98 %. Product ID: ACM143797631. Molecular formula: C15H15ClN4O. Mole weight: 302.76. Alfa Chemistry - ISO 9001:32057 Certified. | |
| SB202190 | SB202190 is a potent p38 MAPK inhibitor targeting p38α/β with IC50 of 50 nM/100 nM in cell-free assays, sometimes used instead of SB 203580 to investigate potential roles for SAPK2a/p38 in vivo. SB202190 inhibits endothelial cell apoptosis via induction of autophagy and heme oxygenase-1. SB202190 significantly suppresses Erastin?dependent ferroptosis. Group: Inhibitors. Alternative Names: FHPI. CAS No. 152121-30-7. Pack Sizes: 25mg. Product ID: S1077. Formula: C20H14N3OF. Smiles: C1=CC(=CC=C1C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)O. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| SB 202190 | Potent and cell permeable p38 MAP kinase inhibitor. Apoptosis inducer. Inhibits p38alpha and beta, but not gamma and delta isoforms. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators. JNK activator. Group: Biochemicals. Alternative Names: 4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol. Grades: Highly Purified. CAS No. 152121-30-7. Pack Sizes: 5mg. Molecular Formula: C20H14FN3O. US Biological Life Sciences. | Worldwide |
| SB 202190 | SB 202190 is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 has anti-cancer activity and rescued memory deficits[1][2]. SB202190 induces autophagy[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 152121-30-7. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg. Product ID: HY-10295. | |
| SB202190 (FHPI, 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole) | Potent and cell permeable p38 MAP kinase inhibitor. Apoptosis inducer. Inhibits p38alpha and beta, but not gamma and delta isoforms. Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators. JNK activator. Group: Biochemicals. Alternative Names: FHPI, 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole. Grades: Highly Purified. CAS No. 152121-30-7. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C20H14FN3O. US Biological Life Sciences. | Worldwide |
| SB 202190 hydrochloride | SB 202190 hydrochloride. Group: Biochemicals. Alternative Names: 4-[4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol monohydrochloride. Grades: Highly Purified. CAS No. 350228-36-3. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C20H15ClFN3O. US Biological Life Sciences. | Worldwide |
| SB 202190 hydrochloride | SB 202190 hydrochloride is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 hydrochloride binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 hydrochloride has anti-cancer activity[1][2]. SB202190 hydrochloride induces autophagy[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 350228-36-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10295A. | |
| SB 202474 | SB 202474, a negative analog of SB203580. SB 202474, which has no ability to inhibit p38 MAPK activity and is widely used as a negative control compound in p38 MAPK studies, also suppressed melanin synthesis induction[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 172747-50-1. Pack Sizes: 1 mg. Product ID: HY-112367. | |
| SB-203207 | SB-203207 is a tRNA synthetase inhibitor produced by Streptomyces sp. NCIMB 40513. Synonyms: SB 203207; SB203207. Molecular formula: C19H31N5O8S. Mole weight: 489.5. |  |
| SB-203208 | SB-203208 is a tRNA synthetase inhibitor produced by Streptomyces sp. NCIMB 40513. Synonyms: SB 203208; SB203208. Molecular formula: C29H42N6O9S. Mole weight: 650.7. | |
| SB 203580 | SB 203580 Inhibitor. Uses: Scientific use. Product Category: T1764. CAS No. 152121-47-6. |  |
| SB203580 (Adezmapimod) | Adezmapimod (SB203580, RWJ 64809, PB 203580) is a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM in THP-1 cells, 10-fold less sensitive to SAPK3(106T) and SAPK4(106T) and blocks PKB phosphorylation with IC50 of 3-5 μM. SB203580 induces mitophagy and autophagy. Group: Inhibitors. Alternative Names: RWJ 64809, PB 203580. CAS No. 152121-47-6. Pack Sizes: 25mg. Product ID: S1076. Formula: C21H16FN3OS. Smiles: CS(=O)C1=CC=C(C=C1)C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F. Storage Conditions: 3 years-20°C (in the dark) powder. | United States; Europe |
| SB 203580 Hydrochloride Salt | SB 203580 Hydrochloride Salt. Group: Biochemicals. Alternative Names: 4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine; hydrochloride; SB203580 hydrochloride; SCHEMBL4890447; HY-10256A. Grades: Highly Purified. CAS No. 869185-85-3. Pack Sizes: 10mg, 25mg. Molecular Formula: C21 H16 FN 3 , Molecular Weight: 413.9. US Biological Life Sciences. | Worldwide |
| SB 203580 sulfone | SB 203580 sulfone is an analog of p38 MAP kinase inhibitor SB 203580. SB 203580 sulfone inhibits the IL-1 production (IC50 of 0.2 μM in monocytes) and binds competitively with CSAID binding proteins (CSBP), inhibits it mediated stress response signaling with an IC50 of 0.03 μM. SB 203580 sulfone inhibits 5-LO with an IC50 value of 24 μM. SB 203580 sulfone can be used in the research of inflammatory diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 152121-46-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112349. | |
| SB 204741 | SB 204741 is a selective and high affinity 5-HT2B antagonist with a pKi value of 7.1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 152239-46-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103153. | |
| SB 204990 | SB 204990 is a potent and specific inhibitor of ATP citrate lyase (ACLY) enzyme. Uses: Scientific research. Category: Signaling pathways. CAS No. 154566-12-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16450. | |
| SB 205384 | SB 205384. Group: Biochemicals. Grades: Purified. CAS No. 160296-13-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SB 206553 hydrochloride | SB 206553 hydrochloride is a high affinity, selective and orally active 5-HT2B / 5-HT2C receptor antagonist (rat 5-HT2B pA2 = 8.89, human 5-HT2C pKi = 7.92)[1]. SB 206553 possesses anxiolytic-like properties[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1197334-04-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-103135. | |
| Sb 216641 hydrochloride | Sb 216641 hydrochloride. Alternative Names: SB 216641, AC1MMVTS, Tocris-1242, SB-216641, Biomol-NT_000123, SureCN2360553, CHEMBL20963, S8942_SIGMA, BPBio1_000134, PDSP1_000533, PDSP2_000531, NCGC00025071-01, NCGC00025071-02, NCGC00025071-03, 170230-39-4, SB-216,641, L001346, BRD-K30867024-001-01-1, N-[3-(2-dimethylamino)ethoxy-4-methoxyphenyl]-2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)-(1,1-biphenyl)-4-carboxamide, N-[3-(2-dimethylaminoethoxy)-4-methoxyphenyl]-4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzamide. CAS No. 170230-39-4. Purity: >98 %. Product ID: ACM170230394. Molecular formula: C28H31ClN4O4. Mole weight: 523.02. IUPAC Name: N-[3-[2-(dimethylamino)ethoxy]-4-methoxyphenyl]-4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzamide. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Sb 216641 hydrochloride | Sb 216641 hydrochloride. Alternative Names: SB 216641 HYDROCHLORIDE;N-[3-[3-(DIMETHYLAMINO)ETHOXY]-4-METHOXYPHENYL]-2'-METHYL-4'-(5-METHYL-1,2,4-OXADIAZOL-3-YL)-[1,1'-BIPHENYL]-4-CARBOXAMIDE HYDROCHLORIDE. CAS No. 170230-44-1. Product ID: ACM170230441. Molecular formula: C28H31ClN4O4. Mole weight: 523.02. Alfa Chemistry - ISO 9001:32057 Certified. | |
| SB 216763 | SB 216763 is potent, selective and ATP-competitive GSK-3 inhibitor with IC50s of 34.3 nM for both GSK-3α and GSK-3β. Uses: Scientific research. Category: Signaling pathways. CAS No. 280744-09-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12012. | |
| SB 218078 | SB 218078. Group: Biochemicals. Grades: Purified. CAS No. 135897-06-2. Pack Sizes: 1mg, 10mg. US Biological Life Sciences. | Worldwide |
| SB-218078 | SB-218078 is a potent, selective, ATP-competitive and cell-permeable checkpoint kinase 1 (Chk1) inhibitor that inhibits Chk1 phosphorylation of cdc25C with an IC50 of 15 nM. SB-218078 is less potently inhibits Cdc2 (IC50 of 250 nM) and PKC (IC50 of 1000 nM). SB-218078 causes apoptosis by DNA damage and cell cycle arrest[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 135897-06-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-107407. | |
| SB-219383 | SB-219383 is a tyrosyl tRNA synthetase inhibitor produced by Micromonospora sp. NCIMB 40684. Synonyms: SB 219383; SB219383. Molecular formula: C17H23N3O9. Mole weight: 413.4. | |
| SB-222200 | SB-222200 is a potent, selective, orally active and blood-brain barrier (BBB) penetrant NK-3 receptor antagonist. SB-222200 is developed for central nervous system (CNS) disorders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 174635-69-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-15722. | |
| Sb-224289 hydrochloride | Sb-224289 hydrochloride. CAS No. 180084-26-8. Purity: 96%. Product ID: ACM180084268. Molecular formula: C32H32N4O3.HCl. Mole weight: 557.08. IUPAC Name: [4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]phenyl]-(1-methylspiro[6,7-dihydro-2H-furo[2,3-f]indole-3,4-piperidine]-5-yl)methanone;hydrochloride. Alfa Chemistry - ISO 9001:32057 Certified. | |
| SB-224289 hydrochloride | SB-224289 hydrochloride is a selective 5-HT1B receptor antagonist, with anxiolytic effect. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SB-224289A. CAS No. 180084-26-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101105A. | |
| SB 22484 | SB 22484 is a member of the aurodox type antibiotic group produced in submerged-fermentation cultures of Streptomyces sp. NRRL 15496. It is composed of two pairs of isomers with MW's of 752 and 766. It strongly inhibited neisseriae and were also active against Streptococci, Ureaplasma urealyticum and Haemophilus influenzae. Synonyms: SB-22484; SB22484; Antibiotic SB 22484. | |
| SB225002 | SB225002, a potent, selective and non-peptide CXCR2 antagonist, inhibits 125I-IL-8 binding to CXCR2 with an IC50 of 22 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 182498-32-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 1 g. Product ID: HY-16711. | |
| SB 225002 | SB225002 is a potent, and selective CXCR2 antagonist with IC50 of 22 nM for inhibiting interleukin IL-8 binding to CXCR2, > 150-fold selectivity over the other 7-TMRs tested. Group: Inhibitors. CAS No. 182498-32-4. Pack Sizes: 10mg. Product ID: S7651. Formula: C13H10BrN3O4. Smiles: C1=CC=C(C(=C1)NC(=O)NC2=C(C=C(C=C2)[N+](=O)[O-])O)Br. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| SB 239063 | SB 239063 is a potent, selective and orally active p38 MAPK inhibitor, exhibits an IC50 of 44 nM for recombinant purified human p38α, with equipotent inhibitory activity against p38α and p38β. SB 239063 has no effect on p38γ or p38δ. With anti-asthma activity and also be used to enhance memory which is impaired due to aging or medical conditions, such as, AD. SB 239063 can penetrate the blood brain barrier (BBB)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 193551-21-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-11068. | |
| SB 242084 | SB 242084 is a selective, competitive and high-affinity (pKi=9.0) 5-HT2C receptor antagonist (crosses the blood-brain barrier). SB 242084 increases basal activity of dopaminergic neurons in the ventral tegmental area (VTA) of the midbrain and dopamine release in the vomeronasal nucleus. SB 242084 also increases mitochondrial gene expression and oxidative metabolism via 5-HT2A receptor. SB 242084 has good research potential in the negative symptoms of anxiety, depression and schizophrenia, as well as in acute organ damage[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 181632-25-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13409. | |
| SB 242084 dihydrochloride | SB 242084 dihydrochloride is a selective, competitive and high-affinity (pKi=9.0) 5-HT2C receptor antagonist (crosses the blood-brain barrier). SB 242084 dihydrochloride increases basal activity of dopaminergic neurons in the ventral tegmental area (VTA) of the midbrain and dopamine release in the vomeronasal nucleus. SB 242084 dihydrochloride also increases mitochondrial gene expression and oxidative metabolism via 5-HT2A receptor. SB 242084 dihydrochloride has good research potential in the negative symptoms of anxiety, depression and schizophrenia, as well as in acute organ damage[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1049747-87-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13409A. | |
| Sb 242084 hydrochloride | Sb 242084 hydrochloride. CAS No. 1049747-87-6. Product ID: ACM1049747876. Molecular formula: C21H19ClN4O2.2HCl. Alfa Chemistry - ISO 9001:32057 Certified. | |
| SB 242084 Hydrochloride (5-HT2C Receptor Antagonist, SB 242084 Hydrochloride, SB-242084 Hydrochloride, SB242084 Hydrochloride) | A selective, brain-penetrant 5-HT2C receptor antagonist (pKi 8.2-9.0 ), with some effects on the 5-HT2B receptor (pKi 6.8-7.0) and 5-HT2A receptor (pKi 6.1-6.8). SB 242084 has been shown to increase the effectiveness of the selective serotonin reuptake inhibitor (SSRI) class of antidepressants, and may also reduce their side effects. In animal studies, SB-242,084 produced stimulant-type activity and reinforcing effects, somewhat similar to but much weaker than cocaine or amphetamines. In vivo (ocular) IC50 values reported at 2.08uM. Group: Biochemicals. Grades: Highly Purified. CAS No. 181632-25-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| SB 243213 dihydrochloride | SB 243213 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 200940-23-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| SB-253514 | SB-253514 is an inhibitor of lipoprotein associated phospholipase A2 produced by Pseudomonas fluorescens DSM 11579. Synonyms: SB 253514; SB253514. Molecular formula: C28H46N2O9. Mole weight: 554.7. | |
| SB 258719 | SB 258719 is a selective 5-HT7 receptor antagonist with high affinity (pKi=7.5) for the receptor. SB 258719 can be used for the research of cancer and neurological disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 195199-95-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00443. | |
| SB-269970 | SB-269970 is a potent, selective and brain-penetrant 5-HT7 receptor antagonist with a pKi of 8.3. SB-269970 exhibits >50-fold selectivity against other 5-HT receptors[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 201038-74-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15370. | |
| SB-269970 hydrochloride | SB-269970 hydrochloride is a potent, selective and brain-penetrant 5-HT7 receptor antagonist with a pKi of 8.3. SB-269970 hydrochloride exhibits >50-fold selectivity against other 5-HT receptors[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SB-269970A. CAS No. 261901-57-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15370A. | |
| SB-269970 Hydrochloride (5-HT7 Serotonin Receptor Antagonist, SB-269970, SB 26,970, SB 26,970) | A selective 5-HT7 receptor antagonist. Extremely potent in vivo and in vitro. Chronic or acute (even single dose) administration of SB269970 induces functional desensitization of the 5-HT7 receptor system, which precedes changes in the receptor density. This mechanism may be responsible for the rapid antidepressant-like effect of the 5-HT7 antagonist in animal models. SB-269970 is an analogue of SB-258719 and has been shown to have at least 100 fold selectivity versus all other 5-HT receptor subtypes except the human 5-HT5A receptor (pKi values are 8.9, 7.2 and 6.0 for 5-HT7A, 5-HT5A and 5-HT1B). Group: Biochemicals. Grades: Highly Purified. CAS No. 261901-57-9. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S·HCl. US Biological Life Sciences. | Worldwide |
| SB 271046 Hydrochloride | SB 271046 Hydrochloride (SB 271046A) is a potent, selective, orally active and BBB-permeable 5-HT6 receptor antagonist with pKi of 9.02, 8.55, and 8.81 for rat, pig and human, respectively. SB 271046 Hydrochloride is over 200 fold selective for the 5-HT6 receptor vs 55 other receptors, binding sites and ion channels. Anticonvulsant activity (EC50=0.16 μM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SB 271046A. CAS No. 209481-24-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-14336A. | |
| SB-273005 | SB-273005 is an orally active non-peptide αvβ3 integrin antagonist with Ki values of 1.2 nM and 0.3 nM for αvβ3 and αvβ5, respectively. SB-273005 blocks the binding of integrins to the RGD sequence in the extracellular matrix. SB-273005 inhibits Rictor phosphorylation and reduces IL-10 secretion. SB-273005 inhibits inflammation, prevents bone loss, regulates vascular smooth muscle function, and reverses pregnancy-induced immune deviation. SB-273005 can be used in the study of rheumatoid arthritis, osteoporosis, and aneurysms. [1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 205678-31-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19307. | |
| Sb 277011 hydrochloride | Sb 277011 hydrochloride. Alternative Names: SB 277011 Hydrochloride;N-[trans-4-[2-(6-Cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]- 4-quinolinecarboxaMide Hydrochloride;SB 277011A Hydrochloride;SB 277211 Hydrochloride;SB-277011-A hydrochloride hydrate. CAS No. 215804-67-4. Purity: 98%+. Product ID: ACM215804674. Molecular formula: C28H30N4O. Mole weight: 438.564. IUPAC Name: N-[4-[2-(6-cyano-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]cyclohexyl]quinoline-4-carboxamide. Canonical SMILES: C1CC(CCC1CCN2CCC3=C(C2)C=CC(=C3)C#N)NC(=O)C4=CC=NC5=CC=CC=C45. Alfa Chemistry - ISO 9001:32057 Certified. | |
| SB 277011 hydrochloride | SB 277011 hydrochloride. Group: Biochemicals. Alternative Names: N-[trans-4-[2- (6-Cyano-3, 4-dihydro-2 (1H) -isoquinolinyl) ethyl]cyclohexyl]-4-quinolinecarboxamide hydrochloride; SB 277011A hydrochloride; SB 277211 hydrochloride. Grades: Highly Purified. CAS No. 215804-67-4. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C28H31ClN4O. US Biological Life Sciences. | Worldwide |
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