A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Saquinavir (Ro 31-8959) is an orally active HIV protease inhibitor that can be used in the research of AIDS. Saquinavir also has anti-inflammatory activity and can induce apoptosis of human red blood cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro 31-8959. CAS No. 127779-20-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17007.
Saquinavir-d9
Labeled Saquinavir. A selective HIV protease inhibitor. Antiviral. Group: Biochemicals. Alternative Names: (2S) -N1 [ (1S, 2R) -3- [ (3S, 4aS, 8aS) -3- [ [ (1, 1-Dimethylethyl) amino] carbonyl] octahydro-2- (1H) -isoquinolinyl] -2-hydroxy-1- (phenylmethyl) propyl] -2- [ (2-quinolinylcarbonyl) amino] butanediamide-d9; Fortovase-d9; Invirase-d9; Ro 31-8959-d9. Grades: Highly Purified. CAS No. 1356355-11-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Saquinavir mesylate
Saquinavir mesylate. Group: Biochemicals. Grades: Purified. CAS No. 149845-06-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Saquinavir mesylate
Saquinavir (Ro 31-8959) mesylate is an orally active HIV protease inhibitor that can be used in the research of AIDS. Saquinavir mesylate also has anti-inflammatory activity and can induce apoptosis of human red blood cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro 31-8959/003. CAS No. 149845-06-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17003.
SAR131675
SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM. SAR131675 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1433953-83-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15458.
SAR131675
SAR131675 dose dependently inhibits the proliferation of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD, with an IC50 of about 20 nM. Alternative Names: (R)-2-amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methylbut-1-yn-1-yl)-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide; 1,8-Naphthyridine-3-carboxamide, 2-amino-1-ethyl-1,4-dihydro-7-[(3R)-3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl]-N-methyl-4-oxo-. Grades: >98%. CAS No. 1433953-83-3. Molecular formula: C18H22N4O4. Mole weight: 358.39.
SAR131675
SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells. SAR131675 also dose dependently inhibited the proliferation of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD. Group: Biochemicals. Alternative Names: 2-Amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl)-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide; 2-Amino-1-ethyl-1,4-dihydro-7-(3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl)-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide. Grades: Highly Purified. CAS No. 1092538-80-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C??H??N?O?, Molecular Weight: 358.39. US Biological Life Sciences.
Worldwide
SAR-20347
SAR-20347 is a dual inhibitor of JAK1 and tyrosine kinase 2 (TYK2) with IC50 values of 23 and 0.6 nM, respectively. It also exhibits slight inhibitory effects gainst JAK2 and JAK3. Alternative Names: 2-(2-Chloro-6-fluorophenyl)-5-[[4-(4-morpholinylcarbonyl)phenyl]amino]-4-oxazolecarboxamide; SAR 20347; SAR20347. CAS No. 1450881-55-6. Molecular formula: C21H18ClFN4O4. Mole weight: 444.84.
SAR247799
SAR247799 (S1P1 agonist 3) is an oral activity, selective G-protein-biased sphingosine-1 phosphate receptor-1 (S1P1 ) agonist, with EC50s rang from 12.6 to 493 nM in S1P1-overexpressing cells and HUVECs. SAR247799 can be used for the research of endothelial protection, including type-2 diabetes, metabolic syndrome[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S1P1 agonist 3. CAS No. 1315311-14-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115831.
SAR405
SAR405 is a first-in-class, selective, and ATP-competitive PI3K class III (PIK3C3) isoform Vps34 inhibitor (IC50=1.2 nM; Kd=1.5 nM). SAR405 inhibits autophagy induced either by starvation or by mTOR inhibition. Anticancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1523406-39-4. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12481.
SAR405
SAR405 is a low-molecular-mass kinase inhibitor of PIK3C3/Vps34 (KD 1.5 nM) showing high selectivity and not be active up to 10 μM on class I and class II PI3Ks as well as on mTOR. SAR405 prevents autophagy and synergizes with MTOR (mechanistic target of rapamycin) inhibition in tumor cells. Group: Inhibitors. CAS No. 1523406-39-4. Pack Sizes: 5mg. Product ID: S7682. Formula: C19H21ClF3N5O2. Smiles: CC1COCCN1C2=CC(=O)N3CCC(N(C3=N2)CC4=CC(=CN=C4)Cl)C(F)(F)F. Storage Conditions: 2 years -80 in solvent.
United States; Europe
SAR-405
SAR-405 is a potent and selective inhibitor of phosphoinositide 3-kinase (PI3K) class III isoform Vps34 (IC50 = 1.2 nM, Kd=1.5 nM) without disrupting other PI3K isoforms and mTOR (IC50 > 10,000 nM). Concomitant inhibition of Vps34 and mTOR, with SAR405 and mTOR inhibitor everolimus, results in synergistic antiproliferative activity in renal tumor cell lines. Alternative Names: SAR 405; SAR405; 4H-Pyrimido[1,2-a]pyrimidin-4-one, 9-[(5-chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-, (8S)-; (8S)-9-[(5-Chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-4H-pyrimido[1,2-a]pyrimidin-4-one. CAS No. 1523406-39-4. Molecular formula: C19H21ClF3N5O2. Mole weight: 443.85.
SAR407899
SAR407899 is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively. SAR407899 shows stable inhibition of migrasome formation. Uses: Scientific research. Category: Signaling pathways. CAS No. 923359-38-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15687A.
SAR441255
SAR441255 is a synthetic peptide agonist of the GLP-1, GCG, and GIP receptors. SAR441255 showed substantial body weight loss and improved glucose control in diabetic obese monkeys. Alternative Names: H-Aib-HGTFTSDLSKL-K(γGlu-γGlu-Palm acid)-EEQRQ-AibEFIEWLKA-dAla-GPPS-Aib-KPPPK-NH2. Molecular formula: C206H323N51O66. Mole weight: 4570.06.
SAR502250
SAR502250 is a potent, selective, ATP competitive, orally active and brain-penetrant inhibitor of GSK3, with an IC50 of 12 nM for human GSK-3β. SAR502250 displays antidepressant-like activity. SAR502250 can be used for the research of Alzheimers disease (AD)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 503860-57-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137472.
SAR629
SAR629 is a potent monoglyceride lipase (MGL) covalent inhibitor. SAR629 also inhibits 2-Arachidonoylglycerol (2-AG) degradation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1221418-42-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118653.
SAR7334
SAR7334 is a potent and specific TRPC6 inhibitor, inhibiting TRPC6 currents with IC50 of 7.9 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1333210-07-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15699.
SAR7334
SAR7334, a TRPC6 inhibitor, could be valuable in studying sorts of diseases related to TRPC. Uses: Sar7334 is a trpc6 inhibitor that could be valuable in studying sorts of diseases related to trpc. Alternative Names: SAR7334; CPA1588; SAR 7334; CPA 1588; SAR-7334; CPA-1588; 4-(((1R,2R)-2-((R)-3-aminopiperidin-1-yl)-2,3-dihydro-1H-inden-1-yl)oxy)-3-chlorobenzonitrile; 1333207-63-8; 1333210-07-3; C21H22ClN3O. Grades: 98%. CAS No. 1333210-07-3. Molecular formula: C21H22ClN3O. Mole weight: 367.87.
SAR7334 hydrochloride
SAR7334 hydrochloride is a potent and specific TRPC6 inhibitor, inhibiting TRPC6 currents with IC50 of 7.9 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1333207-63-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15699A.
Saracatinib
Saracatinib (AZD0530) is a potent Src family inhibitor with IC50s of 2.7 to 11 nM for c-Src, Lck, c-YES, Lyn, Fyn, Fgr, and Blk. Saracatinib shows high selectivity over other tyrosine kinases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD0530. CAS No. 379231-04-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10234.
Saracatinib
Saracatinib, also known as AZD0530, is an orally available dual-specific inhibitor of Src and Abl with anti-invasive and anti-tumor activities. Src and Abl are protein tyrosine kinases that are overexpressed in chronic myeloid leukemia cells. Saracatinib binds to and inhibits these tyrosine kinases and their effects on cell motility, cell migration, adhesion, invasion, proliferation, differentiation, and survival. Specifically, Saracatinib inhibits Src kinase-mediated osteoclast bone resorption. Uses: Antineoplastic agents. Alternative Names: AZD 0530; AZD-0530; AZD0530. Grades: >98%. CAS No. 379231-04-6. Molecular formula: C27H32ClN5O5. Mole weight: 542.03.
Saracatinib
An oral, selective dual inhibitor of Src and ABL kinase. Group: Biochemicals. Alternative Names: N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine; 7- [2- [4-Methylpiperazin-1-yl] ethoxy] -5- [ [tetrahydropyran-4-yl] oxy] -4- [ [6-chloro-2, 3-methylenedioxyphenyl] amino] quinazoline. Grades: Highly Purified. CAS No. 379231-04-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg. US Biological Life Sciences.
Worldwide
Saracatinib (AZD0530)
Saracatinib (AZD0530) is a potent Src inhibitor with IC50 of 2.7 nM in cell-free assays, and potent to c-Yes, Fyn, Lyn, Blk, Fgr and Lck; less active for Abl and EGFR (L858R and L861Q). Saracatinib induces autophagy. Phase 2/3. Group: Inhibitors. CAS No. 379231-04-6. Pack Sizes: 10mg. Product ID: S1006. Formula: C27H32ClN5O5. Smiles: CN1CCN(CC1)CCOC2=CC3=C(C(=C2)OC4CCOCC4)C(=NC=N3)NC5=C(C=CC6=C5OCO6)Cl. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Saracatinib difumarate
Saracatinib (AZD0530) difumarate is a potent Src inhibitor with IC50 values of 2.7-11 nM for c-Src, Lck, c-YES, Lyn, Fyn, Fgr and Blk, and is selective for other tyrosine kinases. [1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD0530 difumarate. CAS No. 893428-72-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10234A.
Sarafloxacin
Sarafloxacin. Group: Biochemicals. Grades: Highly Purified. CAS No. 98105-99-8. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C20H17F2N3O3. US Biological Life Sciences.
A Fluorinated quinolone antibacterial. Group: Biochemicals. Alternative Names: 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic Acid. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Sarafloxacin-[d8] Hydrochloride
Sarafloxacin-[d8] Hydrochloride is the labelled hydrochloride form of Sarafloxacin. Sarafloxacin is a quinolone antibiotic drug, inhibiting the topoisomerase II ligase domain. Alternative Names: 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl-d8)-3-quinolinecarboxylic Acid Hydrochloride; A 56620-d8; PD 121960-d8; Sarafin-d8. Grades: >98%. CAS No. 1352879-52-7. Molecular formula: C20H10D8ClF2N3O3. Mole weight: 429.87.
Sarafloxacin-[d8] hydrochloride hydrate
Sarafloxacin-[d8] hydrochloride hydrate is a labelled analogue of Sarafloxacin. Sarafloxacin is a topoisomerase II ligase inhibitor used as a quinolone antibiotic drug. Alternative Names: Sarafloxacin-D8 hydrochloride hydrate; Difloxacino-d8 hydrochloride hydrate; Difloxacinum-d8 hydrochloride hydrate; Sarafloxacino-d8 hydrochloride hydrate; Sarafloxacinum-d8 hydrochloride hydrate; 6-Fluoro-1-(4-fluorophenyl)-4-oxo-7-piperazine-D8-1-yl-1,4-dihydroquinoline-3-carboxylic acid hydrochloride hydrate. Grades: 95% by HPLC; 98% atom D. Molecular formula: C20H9D8F2N3O3.HCl.H2O. Mole weight: 447.87.
Sarafloxacin hydrochloride
Sarafloxacin is a quinolone antibiotic drug, inhibiting the topoisomerase II ligase domain. It inhibits bacterial Topo II α (DNA gyrase, topoisomerase) and is effective against Mycobacterium tuberculosis. Alternative Names: Sarafloxacin HCl; A-56620; A 56620; A56620. Grades: >98%. CAS No. 91296-87-6. Molecular formula: C20H17F2N3O3.HCl. Mole weight: 421.83.
Sarafloxacin hydrochloride
Sarafloxacin hydrochloride (A-56620 hydrochloride) is a fluoroquinolone Antibacterial agent. Sarafloxacin inhibits the growth of Staphylococcus aureus, Enterobacteriaceae, and both aminoglycoside-sensitive and aminoglycoside-resistant strains of Pseudomonas aeruginosa[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: A-56620 hydrochloride. CAS No. 91296-87-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0343A.
Sarafloxacin hydrochloride
Sarafloxacin hydrochloride. Group: Biochemicals. Alternative Names: 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride; A 56620; PD 121960. Grades: Highly Purified. CAS No. 91296-87-6. Pack Sizes: 500mg, 1g, 2g, 5g. Molecular Formula: C20H18ClF2N3O3. US Biological Life Sciences.
Worldwide
Sarafotoxin S6a
Sarafotoxin S6a. Group: Biochemicals. Grades: Purified. CAS No. 126738-34-9. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
Sarafotoxin S6a
Sarafotoxin S6a is an endothelin receptor agonist (EC50 = 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta, respectively). CAS No. 126738-34-9. Molecular formula: C105H156N28O34S5. Mole weight: 2514.85.
Sarafotoxin S6b
Sarafotoxin S6b is a non-selective endothelin receptor agonist with vasoconstrictor activity. CAS No. 116303-65-2. Molecular formula: C110H159N27O34S5. Mole weight: 2564.
Sarafotoxin S6b
Sarafotoxins (SRTXs) are group of toxins present in a venom of Atractaspis engaddensis, and in clinical trials cause similar symptoms to patients diagnosed with acute giardiasis.[1] Together with endothelins (ETs), they form a homogenous family of strong vasoconstrictor isopeptides. Among them, few slightly different substances can be named, as SRTX-a, SRTX-b, SRTX-c, which were initially derived from Atractaspis engaddensis. Each contains twenty-one amino acid residues that spontaneously fold into a defined tertiary structure with two interchain-cysteine linkages (disulfide bonds) and a long hydrophobic tail.[2] There are also other compounds, however, they are mostly derivations of previously mentioned ones. The main differences in the family of endothelin and sarafotoxins appear at N-terminal of peptides, as C-terminal in all of them is almost the same.[3]. Group: Biochemicals. Grades: Purified. CAS No. 116303-65-2. Pack Sizes: 100ug. Molecular Formula: C110H159N27O34S5, Molecular Weight: 2564. US Biological Life Sciences.
Worldwide
Sarafotoxin S6c
Sarafotoxin S6c. Group: Biochemicals. Grades: Purified. CAS No. 121695-87-2. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
Sarafotoxin S6c
Sarafotoxin S6c is a highly selective ETB endothelin receptor agonist (Ki = 0.29 and 28000 nM at ETB and ETA receptors, respectively). Uses: Vasoconstrictor agents. Alternative Names: Sarafotoxin C; S6C; H-Cys-Thr-Cys-Asn-Asp-Met-Thr-Asp-Glu-Glu-Cys-Leu-Asn-Phe-Cys-His-Gln-Asp-Val-Ile-Trp-OH (Disulfide bridge: Cys1-Cys15, Cys3-Cys11); L-cysteinyl-L-threonyl-L-cysteinyl-L-asparagyl-L-alpha-aspartyl-L-methionyl-L-threonyl-L-alpha-aspartyl-L-alpha-glutamyl-L-alpha-glutamyl-L-cysteinyl-L-leucyl-L-asparagyl-L-phenylalanyl-L-cysteinyl-L-histidyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-isoleucyl-L-tryptophan (1->15),(3->11)-bis(disulfide). Grades: ≥95% by HPLC. CAS No. 121695-87-2. Molecular formula: C103H147N27O37S5. Mole weight: 2515.75.
Saralasin
Saralasin is a competitive and nonselective angiotensin II receptor antagonist. Uses: Angiotensin ii type 1 receptor blockers. Alternative Names: (Sar1,Val5,Ala8)-Angiotensin II; Aralasin; Saralasinum. Grades: ≥97% by HPLC. CAS No. 34273-10-4. Molecular formula: C42H65N13O10. Mole weight: 912.04.
Saralasin
Saralasin. Group: Biochemicals. Grades: Purified. CAS No. 34273-10-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Sarcoma antigen 1 (715-723)
Sarcoma antigen 1 (715-723). Alternative Names: Cancer / testis antigen 14 (715-723); SAGE1 (715-723).
Sarcosine
100g Pack Size. Group: Amino Acids, Biochemicals, Organics, Peptide Reagents. Formula: C3H7NO2. CAS No. 107-97-1. Prepack ID 38645048-100g. Molecular Weight 89.09. See USA prepack pricing.
Sarcosine
Sarcosine is an endogenous GlyT1 inhibitor. Sarcosine displays antipsychotic activity and has the potential to treat schizophrenia. Sarcosine has been shown to potentiate the action of glycine on the NMDA glycine binding site. Uses:
sarcosine, also known as n-methylglycine, is a naturally occurring amino acid derivative that has shown promise in various areas including drug discovery and development. in recent years, there has been growing interest in exploring the pharmacological properties of sarcosine and its derivatives due to their diverse biological activities.
.
sarcosine is a basic derivative of amino acids th. Alternative Names: N-Methylglycine; Sarcosinic acid; Methylglycine; Glycine, N-methyl-. Grades: 98%. CAS No. 107-97-1. Molecular formula: C3H7NO2. Mole weight: 89.09.
Sarcosine
500g Pack Size. Group: Amino Acids, Biochemicals, Organics, Peptide Reagents. Formula: C3H7NO2. CAS No. 107-97-1. Prepack ID 38645048-500g. Molecular Weight 89.09. See USA prepack pricing.
Sarcosine-13C
Sarcosine-13C is an isotope labelled compound of Sarcosine (S140500). Sarcosine is a type 1 glycine transporter inhibitor and a glycine agonist that may be useful for treating schizophrenia. Also, used in the study of the potential therapeutic efficacy of glycine transporter 1 inhibitors in the treatment of central nervous system disorders in human system. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C213CH7NO2, Molecular Weight: 90.09. US Biological Life Sciences.
Worldwide
Sarcosine-13C3
Sarcosine-13C3 is a labelled analogue of Sarcosine (S140500), a type 1 glycine transporter inhibitor and a glycine agonist that may be useful for treating schizophrenia (1). Sarcosine is also a marker for prostate cancer bioagression (2). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: 13C3H7NO2. US Biological Life Sciences.
Worldwide
Sarcosine 99+%
Sarcosine, also known as N-methylglycine, is an intermediate and byproduct in glycine synthesis and degradation. Sarcosine is metabolized to glycine by the enzyme sarcosine dehydrogenase, while glycine-N-methyl transferase generates sarcosine from glycine. Sarcosine is a natural amino acid found in muscles and other body tissues. In the laboratory, it may be synthesized from chloroacetic acid and methylamine. Sarcosine is found naturally as an intermediate in the metabolism of choline to glycine. Sarcosine is sweet to the taste and dissolves in water. It is used in manufacturing biodegradable surfactants and toothpastes as well as in other applications. Group: Biochemicals. Alternative Names: Sar-OH; N-Methylglycine. Grades: Reagent Grade. CAS No. 107-97-1. Pack Sizes: 25g, 100g, 250g, 1Kg, 2.5Kg. US Biological Life Sciences.
Worldwide
Sarcosine amide hydrochloride
Sarcosine amide hydrochloride. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Sarcosine amide hydrochloride
Sarcosine amide hydrochloride. Alternative Names: Sar-NH2 HCl; N-Methylglycine amide hydrochloride. Grades: ≥ 99% (Assay by titration on dried basis). CAS No. 5325-64-4. Molecular formula: C3H8N2O·HCl. Mole weight: 124.57.
Sarcosine benzyl ester 4-toluenesulfonate salt
Sarcosine benzyl ester 4-toluenesulfonate salt. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g. US Biological Life Sciences.
Labeled Sarcosine. Has been found in starfish and sea urchins. It is used as intermediate in the synthesis of antienzyme agents for toothpaste. Found to be a marker for prostate cancer bioagression. Group: Biochemicals. Alternative Names: N-(Methyl-d3)glycine Hydrochloride. Grades: Highly Purified. CAS No. 347840-04-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
sarcosine dehydrogenase
A flavoprotein (FMN). Tetrahydrofolate is also a substrate, being converted to N5,N10-methylenetetrahydrofolate. Group: Enzymes. Synonyms: sarcosine N-demethylase; monomethylglycine dehydrogenase; sarcosine:(acceptor) oxidoreductase (demethylating). Enzyme Commission Number: EC 1.5.8.3. CAS No. 37228-65-2, 93389-49-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1562; sarcosine dehydrogenase; EC 1.5.8.3; 37228-65-2, 93389-49-2; sarcosine N-demethylase; monomethylglycine dehydrogenase; sarcosine:(acceptor) oxidoreductase (demethylating). Cat No: EXWM-1562.
Sarcosine dimethylamide hydrochloride 98+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
sarcosine/dimethylglycine N-methyltransferase
Cells of the oxygen-evolving halotolerant cyanobacterium Aphanocthece halophytica synthesize betaine from glycine by a three-step methylation process. The first enzyme, EC 2.1.1.156, glycine/sarcosine N-methyltransferase, leads to the formation of either sarcosine or N,N-dimethylglycine, which is further methylated to yield betaine (N,N,N-trimethylglycine) by the action of this enzyme. Both of these enzymes can catalyse the formation of N,N-dimethylglycine from sarcosine. The reactions are strongly inhibited by S-adenosyl-L-homocysteine. Group: Enzymes. Synonyms: ApDMT; sarcosine-dimethylglycine methyltransferase; SDMT; sarcosine dimethylglycine N-methyltransferase; S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase. Enzyme Commission Number: EC 2.1.1.157. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1753; sarcosine/dimethylglycine N-methyltransferase; EC 2.1.1.157; ApDMT; sarcosine-dimethylglycine methyltransferase; SDMT; sarcosine dimethylglycine N-methyltransferase; S-adenosyl-L-methionine:N,N-dimethylglycine N-methyltransferase. Cat No: EXWM-1753.
Sarcosine methyl ester hydrochloride 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g. US Biological Life Sciences.
Worldwide
sarcosine oxidase
A flavoprotein (FAD). The flavin is both covalently and non-covalently bound in a molar ratio of 1:1. Group: Enzymes. Enzyme Commission Number: EC 1.5.3.1. CAS No. 9029-22-5. SAO. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1537; sarcosine oxidase; EC 1.5.3.1; 9029-22-5. Cat No: EXWM-1537.
Sarcosine oxidase, Bacillus
Sarcosine oxidase, Bacillus (SAO) can catalyze the oxidative demethylation of sarcosine to generate glycine, H2O2, 5,10-CH2-tetrahydrofolate, which are often used in biochemical reactions[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SAO. CAS No. 9029-22-5. Pack Sizes: 10 KU. Product ID: HY-P2861.
Sarcosine Oxidase from E. coli, Recombinant
Sarcosine oxidase (SAO) is an enzyme that catalyzes the oxidative demethylation of sarcosine to yield glycine, H2O2, 5, 10-CH2-tetrahydrofolate in a reaction requiring H4-tetrahydrofolate and oxygen. sarcosine + H2O + O2=glycine + formaldehyde + H2O2. Group: Enzymes. Synonyms: Sarcosine Oxidase; EC 1.5.3.1; SAO. Enzyme Commission Number: EC 1.5.3.1. Mole weight: ca. 49 kDa. Activity: > 10 U/mg. Appearance: Yellow lyophilizate. Storage: at -20°C. Source: E. coli. Species: E. coli. Sarcosine Oxidase; EC 1.5.3.1; SAO. Cat No: DIA-414.
sarcosine reductase
The reaction is observed only in the direction of sarcosine reduction. The enzyme from Eubacterium acidaminophilum consists of subunits A, B and C. Subunit B contains selenocysteine and a pyruvoyl group, and is responsible for sarcosine binding and methylamine release. Subunit A, which also contains selenocysteine, is reduced by thioredoxin, and is needed to convert the carboxymethyl group into a ketene equivalent, in turn used by subunit C to produce acetyl phosphate. Only subunit B distinguishes this enzyme from EC 1.21.4.2 (glycine reductase) and EC 1.21.4.4 (betaine reductase). Group: Enzymes. Enzyme Commission Number: EC 1.21.4.3. CAS No. 125752-88-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1258; sarcosine reductase; EC 1.21.4.3; 125752-88-7. Cat No: EXWM-1258.
Sarcosine (Standard)
Sarcosine (Standard) is the analytical standard of Sarcosine. This product is intended for research and analytical applications. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Methylglycine (Standard); Sarcosin (Standard). CAS No. 107-97-1. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101037R.
Sarcosine t-butyl ester hydrochloride
Sarcosine t-butyl ester hydrochloride is a reactant used in various syntheses. It was used in the preparation of sulfonamidoisoquinolinyl guanidines which are selective urokinase-type plasminogen activator inhibitors. Also used in the development of pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3). Alternative Names: H-Sar-OtBu HCl; H-MeGly-OtBu HCl; N-α-Methylglycine t-butyl ester hydrochloride. CAS No. 136088-69-2. Molecular formula: C7H16ClNO2. Mole weight: 181.66.
Sarcosine tert-butyl ester hydrochloride
Sarcosine tert-butyl ester hydrochloride is used as an important raw material and intermediate in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. Alternative Names: Sar-OtBu HCl; N-Methylglycine t-butyl ester hydrochloride. Grades: ≥ 99.9 % (HPLC). CAS No. 5616-81-9. Molecular formula: C7H16NO2Cl. Mole weight: 181.7.