American Chemical Suppliers

A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.

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Product
Sipagladenant Sipagladenant (Compound I) is an orally active adenosine receptor A2A inverse agonist[1]. Sipagladenant can be used in frontal lobe dysfunction research[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KW-6356. CAS No. 858979-50-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147400. MedChemExpress MCE
Sipatrigine Sipatrigine. Group: Biochemicals. Grades: Purified. CAS No. 130800-90-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 13
Worldwide
Sipavibart Sipavibart (AZD3152) is a human IgG1 λ2 monoclonal antibody against SARS-CoV-2. Sipavibart is applicable to research related to COVID-19. The isotype control product for Sipavibart is Human IgG1 lambda2, Isotype Control (HY-P990096)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD3152. CAS No. 2768288-97-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990766. MedChemExpress MCE
Sipeimine Sipeimine (Imperialine) is an inhibitor targeting the PI3K/AKT/NF-κB pathway and NLRP3 inflammasome, which can competitively bind to PI3K and p65. Sipeimine inhibits PI3K/AKT phosphorylation, blocks NF-κB nuclear translocation and NLRP3 inflammasome activation. Sipeimine exerts anti-inflammatory activities, inhibits pyroptosis and ferroptosis, and protects the extracellular matrix. Sipeimine can reduce cartilage degradation and synovial inflammation in osteoarthritis and improve PM2.5-induced lung injury. Sipeimine is mainly used in the study of anti-inflammatory and degenerative diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Imperialine. CAS No. 61825-98-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-N0696. MedChemExpress MCE
Siplizumab Siplizumab (MEDI-507) is a humanized IgG1 monoclonal antibody against CD2. Siplizumab depletes T cells, decreases T cell activation, inhibites T cell proliferation and enriches naïve and bona fide regulatory T cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MEDI-507; TCD601. CAS No. 288392-69-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99904. MedChemExpress MCE
Siponimod Siponimod (BAF-312) is an orally active, blood-brain barrier penetrant dual agonist of S1P1/S1P5, with EC50 values of 0.39 nM and 0.98 nM, respectively. Siponimod induces S1P1 internalization, activates GIRK channels, inhibits lymphocyte egress, reduces peripheral lymphocyte counts, triggers transient bradycardia, prevents synaptic neurodegeneration, promotes remyelination, alleviates demyelination, and prevents the loss of GABAergic interneurons. Siponimod can be used in research related to multiple sclerosis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAF-312. CAS No. 1230487-00-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-12355. MedChemExpress MCE
Siponimod hemifumarate Siponimod (BAF-312) hemifumarate, a selective and potent modulator of sphingosine-1-phosphate (S1P) receptors, can be used in the study of multiple sclerosis (MS). Category: Active pharmaceutical ingredients. CAS No. 1234627-85-0. Product ID: API1234627850. Molecular formula: C62H74F6N4O10. Mole weight: 1149.282. Protheragen
Siponimod Impurity 10 Siponimod Impurity 10. Uses: For analytical and research use. Molecular formula: C16H19F3O2. Mole weight: 300.32. Catalog: APB10829. Alfa Chemistry Analytical Products 2
Siponimod Impurity 11 Siponimod Impurity 11. Uses: For analytical and research use. CAS No. 1378888-43-7. Molecular formula: C11H14O2. Mole weight: 178.23. Catalog: APB1378888437. Alfa Chemistry Analytical Products 3
Siponimod Impurity 12 Siponimod Impurity 12. Uses: For analytical and research use. CAS No. 800379-62-8. Molecular formula: C14H18F3NO. Mole weight: 273.3. Catalog: APB800379628. Alfa Chemistry Analytical Products 4
Siponimod Impurity 13 Siponimod Impurity 13. Uses: For analytical and research use. CAS No. 2474774-17-7. Molecular formula: C15H19NO3. Mole weight: 261.32. Catalog: APB2474774177. Alfa Chemistry Analytical Products 3
Siponimod Impurity 14 Siponimod Impurity 14. Uses: For analytical and research use. Molecular formula: C29H37F3N2O4. Mole weight: 534.62. Catalog: APB10830. Alfa Chemistry Analytical Products 2
Siponimod Impurity 15 Siponimod Impurity 15. Uses: For analytical and research use. Molecular formula: C29H35F3N2O3. Mole weight: 516.61. Catalog: APB10831. Alfa Chemistry Analytical Products 2
Siponimod Impurity 8 Siponimod Impurity 8. Uses: For analytical and research use. Molecular formula: C32H40N2O5. Mole weight: 532.68. Catalog: APB10827. Alfa Chemistry Analytical Products 2
Siponimod Impurity 9 Siponimod Impurity 9. Uses: For analytical and research use. Molecular formula: C32H40N2O5. Mole weight: 532.68. Catalog: APB10828. Alfa Chemistry Analytical Products 2
Siramesine Siramesine (Lu 28-179) is a potent sigma-2 receptor agonist. Siramesine has a subnanomolar affinity for sigma-2 receptors (IC50=0.12?nM) and exhibits a 140-fold selectivity for sigma-2 receptors over sigma-1 receptors (IC50=17?nM). Siramesine triggers cell death through destabilisation of mitochondria, but not lysosomes. Anti-cancer activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Lu 28-179. CAS No. 147817-50-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14221. MedChemExpress MCE
Siramesine hydrochloride Siramesine (Lu 28-179) hydrochloride is a potent sigma-2 receptor agonist. Siramesine hydrochloride has a subnanomolar affinity for sigma-2 receptors (IC50=0.12 nM) and exhibits a 140-fold selectivity for sigma-2 receptors over sigma-1 receptors (IC50=17 nM). Siramesine hydrochloride triggers cell death through destabilisation of mitochondria, but not lysosomes. Anti-cancer activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Lu 28-179 hydrochloride. CAS No. 224177-60-0. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14221A. MedChemExpress MCE
Siremadlin Siremadlin (NVP-HDM201) is a potent, orally bioavailable and highly specific p53-MDM2 interaction inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NVP-HDM201; HDM201. CAS No. 1448867-41-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18658. MedChemExpress MCE
Sirexatamab Sirexatamab (DKN-01) is a humanized IgG4 monoclonal antibody that can bind to and neutralize circulating DKK1. Sirexatamab exhibits antitumor activity in tumor models expressing DKK1[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DKN-01; LY-2812176. CAS No. 2414962-49-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99906. MedChemExpress MCE
Sirius Red Powder C.I. 35780 25g Pack Size. Group: Analytical Reagents, Stains & Indicators. Formula: C45H32N10O21S6. CAS No. 2610-10-8. Prepack ID 90028587-25g. Molecular Weight 1373.05. See USA prepack pricing. Molekula Americas
siRNA Electroporation Buffer (30 ml) Electroporation buffer optimized for high transfection efficacy of siRNA, miRNA, and mRNA into primary cultures and hard-to-transfect cell lines. Uses: Electroporation of DNA, RNA, protein and small molecules. Product ID: 4066. Altogen
Nevada, Texas, USA
Sirodesmin A Sirodesmin A is a diketopiperazine antibiotic isolated from the culture broth of Microsphaeropsis sp. FL-16144. TAN-1496 inhibited the relaxation of supercoiled pBR322 DNA by calf thymus topoisomerase I but did not affect the decatenation of kinetoplast DNA by calf thymus topoisomerase II at concentration up to 500 microM. Synonyms: TAN-1496B; TAN 1496B. CAS No. 52988-50-8. Molecular formula: C20H26N2O8S2. Mole weight: 486.6. BOC Sciences 12
Sirodesmin B It is produced by the strain of Sirodesmum diversum. It has antiviral effect. Synonyms: Spiro[furan-2(3H),9'(10'H)-[5,11a](iminomethano)[11aH]cyclopenta[4,5]pyrrolo[2,1-e][1,2,3,4,6]tetrathiazocine]-3,6',12'(5'H)-trione, 10'-(acetyloxy)-4,5,7'a,8',10'a,11'-hexahydro-10'ahydroxy-5'-(hydroxymethyl)-4,4,5,13'-tetramethyl-, (2R,5'R,7'aR,10'S,10'aS,11aR)-. CAS No. 52988-51-9. Molecular formula: C20H26N2O8S4. Mole weight: 550.69. BOC Sciences 12
Sirodesmin C It is produced by the strain of Sirodesmum diversum. It has antiviral effect. Synonyms: Spiro[furan-2(3H),8'(9'H)-[4,10a](iminomethano)[10aH]cyclopenta[4,5]pyrrolo[2,1-d][1,2,3,5]trithiazepine]-3,5',11'(4'H)-trione, 9'-(acetyloxy)hexahydro-9'a-hydroxy-4'-(hydroxymethyl)-4,4,5,12'-tetramethyl-, (2R,4'R,5R,6'aR,9'S,9'aS,10aR)-. CAS No. 52988-52-0. Molecular formula: C20H26N2O8S3. Mole weight: 518.62. BOC Sciences 12
Sirodesmin G It is produced by the strain of Sirodesmum diversum. It has antiviral effect. CAS No. 64599-26-4. Molecular formula: C20H26N2O8S2. Mole weight: 486.56. BOC Sciences 12
sirohydrochlorin cobaltochelatase This enzyme is a type II chelatase, being either a monomer (CbiX) or a homodimer (CibK) and being ATP-independent. CbiK from Salmonella enterica uses precorrin-2 as the substrate to yield cobalt-precorrin-2. The enzyme contains two histidines at the active site that are thought to be involved in the deprotonation of the tetrapyrrole substrate as well as in metal binding. CbiX from Bacillus megaterium inserts cobalt at the level of sirohydrochlorin (factor-II) rather than precorrin-2. Group: Enzymes. Synonyms: CbiK; CbiX; CbiXS; anaerobic cobalt chelatase; cobaltochelatase [ambiguous]; sirohydrochlorin cobalt-lyase (incorrect). Enzyme Commission Number: EC 4.99.1.3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5360; sirohydrochlorin cobaltochelatase; EC 4.99.1.3; CbiK; CbiX; CbiXS; anaerobic cobalt chelatase; cobaltochelatase [ambiguous]; sirohydrochlorin cobalt-lyase (incorrect). Cat No: EXWM-5360. Creative Enzymes
sirohydrochlorin ferrochelatase This enzyme catalyses the third of three steps leading to the formation of siroheme from uroporphyrinogen III. The first step involves the donation of two S-adenosyl-L-methionine-derived methyl groups to carbons 2 and 7 of uroporphyrinogen III to form precorrin-2 (EC 2.1.1.107, uroporphyrin-III C-methyltransferase) and the second step involves an NAD+-dependent dehydrogenation to form sirohydrochlorin from precorrin-2 (EC 1.3.1.76, precorrin-2 dehydrogenase). In Saccharomyces cerevisiae, the last two steps are carried out by a single bifunctional enzyme, Met8p. In some bacteria, steps 1-3 are catalysed by a single multifunctional protein called CysG, whereas in Bacillus megaterium, three separate enzymes carry out each of the steps, with SirB being responsible for the above reaction. Group: Enzymes. Synonyms: CysG; Met8P; SirB; sirohydrochlorin ferro-lyase (incorrect). Enzyme Commission Number: EC 4.99.1.4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5361; sirohydrochlorin ferrochelatase; EC 4.99.1.4; CysG; Met8P; SirB; sirohydrochlorin ferro-lyase (incorrect). Cat No: EXWM-5361. Creative Enzymes
Sirolimus Liposome Sirolimus, a metabolite of AYBP44 (streptomyces hygroscopicus), is not only a low-toxicity antibiotic but also a novel immunosuppressant. This product is a pre-formulated liposome with sirolimus. It is only for research purposes. Group: Drug-loaded liposome. Creative Biolabs
Sirpiglenastat Sirpiglenastat (DRP-104) is a broad acting glutamine antagonist. Sirpiglenastat has anticancer effects by directly targeting tumor metabolism and simultaneously inducing a potent antitumor immune response[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DRP-104. CAS No. 2079939-05-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-132832. MedChemExpress MCE
SirReal-1 SirReal-1 is a potent and selective Sirt2 inhibitor (IC50 = 3.7 μM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 801227-82-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123653. MedChemExpress MCE
SirReal2 SirReal2 is a potent, isotype-selective Sirt2 inhibitor with an IC50 value of 140?nM and has very little effect on the activities of Sirt3-5. SirReal2 leads to tubulin hyperacetylation in HeLa cells and induces destabilization of the checkpoint protein BubR1. SirReal2 combined with VS-5584 (HY-16585) suppresses tumor growth and extends the survival rate of mice in tumor xenograft model. SirReal2 is is promising for research of cancer, inflammation and neurodegeneration[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 709002-46-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100591. MedChemExpress MCE
SirReal 2 SirReal 2. Group: Biochemicals. Grades: Purified. CAS No. 709002-46-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 13
Worldwide
SIRT1 Antibody [N11B23] SirT1,Sirt1(Sir2). Group: Antibodies. Alternative Names: SirT1,Sir2. CAS No. Pack Sizes: 20ul. Product ID: F0526. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. Selleck Chemicals
United States; Europe
Sirt2-IN-1 Sirt2-IN-1 (Compound 9) is a sirtuin 2 (Sirt2) inhibitor with an IC50 of 163 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1862238-00-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-112427. MedChemExpress MCE
Sirt2-IN-2 Sirt2-IN-2 (Compound 10) is a selective Sirt2 inhibitor with an IC50 of 0.118 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1862238-01-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112428. MedChemExpress MCE
SIRT3 activator 2 SIRT3 activator 2 (compound 2a) is a SIRT3 activator. SIRT3 activator 2 improved the thermal stability of SIRT3 in SH-SY5Y cells, indicating that it can directly bind to SIRT3, has SIRT3 dependency in SH-SY5Y to clear α-Syn. SIRT3 activator 2 improves motor function in Parkinson mice, preventing Parkinson (DA) neuron loss in the substantia nigra in a dose-dependent manner[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3061491-60-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163987. MedChemExpress MCE
SIRT3-IN-1 SIRT3-IN-1 (compound 17f) is a SIRT3 inhibitor, with IC50 of 0.043 μM. SIRT3-IN-1 can be used in the research of acute leukemia (AML)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3062836-46-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161920. MedChemExpress MCE
SIRT4-IN-1 SIRT4-IN-1 is a selective and potent Sirtuin 4 (Sirt4) inhibitor with an IC50 of 16 μM for hSirt4. SIRT4-IN-1 also inhibits hSirt1, hSirt2, hSirt3, hSirt4 and hSirt6. SIRT4-IN-1 competes with acyl peptide substrate for Sirt4's acyl binding site, and is noncompetitive with NAD+. SIRT4-IN-1 increases glutamate dehydrogenase (GDH) activity and rescues pyruvate dehydrogenase (PDH) activity. SIRT4-IN-1 inhibits adipocyte differentiation and suppresses Sirt4 overexpression-induced increased differentiation. SIRT4-IN-1 can be used for the researches of cancer and metabolic disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3030697-87-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163316. MedChemExpress MCE
SIRT5 inhibitor 1 SIRT5 inhibitor 1 is a potent Human Sirtuin 5 deacylase inhibitor, with an IC50 of 0.11 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 2166487-21-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-112634. MedChemExpress MCE
SIRT6-IN-2 SIRT6-IN-2 (Compound 5) is a selective and competitive SIRT6 inhibitor (IC50: 34 μM). SIRT6-IN-2 increases acetylation of H3K9 and increases glucose uptake in cultured cells. SIRT6-IN-2 also reduces T cell proliferation. SIRT6-IN-2 has immunosuppressive and chemosensitizing effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 891002-11-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103721. MedChemExpress MCE
SIRT7 inhibitor 97491 SIRT7 inhibitor 97491, a potent SIRT7 inhibitor with an IC50 of 325 nM, reduces deacetylase activity of SIRT7 in a dose-dependent manner. SIRT7 inhibitor 97491 prevents tumor progression by increasing p53 stability through acetylation at K373/382. SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway.[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1807758-81-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135899. MedChemExpress MCE
Sirtinol Sirtinol is a sirtuin (SIRT) inhibitor, with IC50s of 48 μM, 57.7 μM and 131 μM for ySir2, hSIRT2 and hSIRT2, respectively[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 410536-97-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13515. MedChemExpress MCE
Sirtinol Sirtinol is a known inhibitor of the NAD+-Dependent Protein Desuccinylase and Demalonylase Sirt5 and exhibits anticancer properties. Group: Biochemicals. Alternative Names: 2-[[ (2-hydroxy-1-naphthalenyl) methylene]amino]-N- (1-phenylethyl) -benzamide; Sir Two Inhibitor Naphthol. Grades: Highly Purified. CAS No. 410536-97-9. Pack Sizes: 10mg, 25mg. US Biological Life Sciences. USBiological 13
Worldwide
Sirtinol (SIRT2 Inhibitor Naphthol) Cell-permeable. A selective sirtuin deacetylase inhibitor with IC50 values of 38, 68 and 131uM for SIRT2, Sir2p and SIRT1 respectively. Sirtinol has no effect on HDAC1 activity. Sirtinol inhibits the growth of cancer cells and suppresses inflammatory signaling in human dermal microvascular endothelial cells. Group: Biochemicals. Alternative Names: 2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide. Grades: Highly Purified. CAS No. 410536-97-9. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 13
Worldwide
Sirtinol (Sir Two Inhibitor Naphthol, 2-N-(1-phenethyl)benzamide) Specific cell permeable SIRT1 (sirtuin-1) inhibitor. Senescence-like growth arrest inducer. Platelet aggregation inhibitor. Apoptosis inducer. Group: Biochemicals. Alternative Names: Sir Two Inhibitor Naphthol, 2--N-(1-phenethyl)benzamide. Grades: Highly Purified. CAS No. 410536-97-9. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. USBiological 13
Worldwide
Sirukumab Sirukumab (CNTO-136) is a humanized monoclonal anti-IL6 (Interleukin Related) IgG1κ antibody. Sirukumab binds to IL6, preventing IL6-mediated signal transduction and activation of transcriptional activators, thereby blocking the downstream biological effects of IL6. Sirukumab can be used in the study of active lupus nephritis and rheumatoid arthritis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CNTO-136. CAS No. 1194585-53-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99316. MedChemExpress MCE
SIS17 SIS17 is a mammalian histone deacetylase 11 (HDAC 11) inhibitor with an IC50 value of 0.83 μM. SIS17 inhibits the demyristoylation of serine hydroxymethyltransferase 2, a substrate of HDAC 11, but does not inhibit other HDACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2374313-54-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128918. MedChemExpress MCE
SIS3 SIS3 is a potent and selective inhibitor of Smad3 with an IC50 of 3 μM for Smad3 phosphorylation. SIS3 inhibits the myofibroblast differentiation of fibroblasts by TGF-β1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 521984-48-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13013. MedChemExpress MCE
SIS3 SIS3. Group: Biochemicals. Grades: Purified. CAS No. 521984-48-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 13
Worldwide
SIS3 free base SIS3 free base is a potent and selective inhibitor of Smad3 phosphorylation. SIS3 free base inhibits the myofibroblast differentiation of fibroblasts by TGF-β1. SIS3 free base does not affect the phosphorylation of Smad2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 521985-36-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100444. MedChemExpress MCE
SIS3 Hydrochloride SIS3, a novel specific inhibitor of Smad3, inhibits TGF-β and activin signaling by suppressing Smad3 phosphorylation without affecting the MAPK/p38, ERK, or PI3-kinase signaling pathways. Group: Inhibitors. CAS No. 521984-48-5. Pack Sizes: 2mg. Product ID: S7959. Formula: C28H27N3O3.HCl. Smiles: CN1C(=C(C2=C1N=CC=C2)C=CC(=O)N3CCC4=CC(=C(C=C4C3)OC)OC)C5=CC=CC=C5.Cl. Storage Conditions: 2 years -80 in solvent. Selleck Chemicals
United States; Europe
Sisomicin Antibacterial. Gentamicin-like aminoglycoside antibiotic; has broad spectrum antibiotic activity. Group: Biochemicals. Alternative Names: O-3-Deoxy-4-C-methyl-3-(methylamino)- β-L-arabinopyranosyl-(1-6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1-4)]-2-deoxy- D-Streptamine; Antibiotic 66-40; Antibiotic 6640; Rickamicin; Sch 13475; Siseptin. Grades: Highly Purified. CAS No. 32385-11-8. Pack Sizes: 1g. US Biological Life Sciences. USBiological 13
Worldwide
Sisomicin It is an aminoglycoside antibiotic produced by the strain of Micromonospora inyoensis NRRL 3292. It has a broad-spectrum antibacterial effects against Gram-positive and Gram-negative bacteria including B. subtilis, S. aureus, E. coli, and P. aeruginosa. It has no cross-resistance to kanamycin, but has cross-resistance to gentamycin. 50 mg/kg of Sisomicin has protective effect on mice infected with Rickettsia spinosa. Uses: Protein synthesis inhibitors. Synonyms: D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1→4)]-2-deoxy-; Antibiotic 6640; SCH 13475; Rickamicin; Sisomycin; Sissomicin; O-3-Deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1→4)]-2-deoxy-D-streptamine; Antibiotic 66-40; BactoCeaze; Ensamycin; Sch 13475; Siseptin. Grade: ≥98%. CAS No. 32385-11-8. Molecular formula: C19H37N5O7. Mole weight: 447.53. BOC Sciences
Sisomicin B It is an aminoglycoside antibiotic produced by the strain of Micromonospora inyoensis. It has broad-spectrum antimicrobial activity. Synonyms: Sisomicin B; 6-O-[3-Deoxy-3-(methylamino)-α-D-xylopyranosyl]-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hexa-4-enopyranosyl)-2-deoxy-D-streptamine; Antibiotic 66-40B; 6640B; D-Streptamine, O-3-deoxy-3-(methylamino)-alpha-D-xylopyranosyl-(1-6)-o-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1-4))-2-deoxy-. CAS No. 53797-16-3. Molecular formula: C18H35N5O7. Mole weight: 433.50. BOC Sciences 12
Sisomicin D It is an aminoglycoside antibiotic produced by the strain of Micromonospora inyoensis. It has broad-spectrum antimicrobial activity. Synonyms: 6-O-[3-Deoxy-3-(methylamino)-β-L-arabinopyranosyl]-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hexa-4-enopyranosyl)-2-deoxy-D-streptamine; Antibiotic 66-40D; 66-40D. CAS No. 53759-50-5. Molecular formula: C18H35N5O7. Mole weight: 433.50. BOC Sciences 12
Sisomicin impurity 1 Sisomicin impurity 1. Uses: For analytical and research use. Molecular formula: C12H24N4O4. Mole weight: 288.35. Catalog: APB11397. Alfa Chemistry Analytical Products 2
Sisomicin impurity 2 Sisomicin impurity 2. Uses: For analytical and research use. Molecular formula: C18H35N5O7. Mole weight: 433.51. Catalog: APB11396. Alfa Chemistry Analytical Products 2
Sisomicin impurity 3 Sisomicin impurity 3. Uses: For analytical and research use. Molecular formula: C18H35N5O7. Mole weight: 433.51. Catalog: APB11399. Alfa Chemistry Analytical Products 2
Sisomicin impurity 4 Sisomicin impurity 4. Uses: For analytical and research use. CAS No. 53759-50-5. Molecular formula: C18H35N5O7. Mole weight: 433.51. Catalog: APB53759505. Alfa Chemistry Analytical Products 4
Sisomicin impurity 5 Sisomicin impurity 5. Uses: For analytical and research use. Molecular formula: C19H35N5O8. Mole weight: 461.52. Catalog: APB11401. Alfa Chemistry Analytical Products 2
Sisomicin impurity 6 Sisomicin impurity 6. Uses: For analytical and research use. CAS No. 53797-16-3. Molecular formula: C18H35N5O7. Mole weight: 433.51. Catalog: APB53797163. Alfa Chemistry Analytical Products 4
Sisomicin impurity 7 Sisomicin impurity 7. Uses: For analytical and research use. Molecular formula: C12H24N4O4. Mole weight: 288.35. Catalog: APB11400. Alfa Chemistry Analytical Products 2
Sisomicin impurity 8 Sisomicin impurity 8. Uses: For analytical and research use. Molecular formula: C18H35N5O7. Mole weight: 433.51. Catalog: APB11402. Alfa Chemistry Analytical Products 2
Sisomicin impurity 9 Sisomicin impurity 9. Uses: For analytical and research use. CAS No. 1154757-24-0. Molecular formula: C25H48N6O10. Mole weight: 592.69. Catalog: APB1154757240. Alfa Chemistry Analytical Products 2
Sisomicin sulfate Sisomicin sulfate is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin sulfate is highly active against Gram-positive bacteria. Uses: Scientific research. Category: Signaling pathways. CAS No. 53179-09-2. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 250 mg; 500 mg. Product ID: HY-B1222. MedChemExpress MCE
Sisomicin sulfate Sisomicin sulfate. Group: Biochemicals. Grades: Highly Purified. CAS No. 53179-09-2. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: 2C19H37N5O7·5H2SO4. US Biological Life Sciences. USBiological 13
Worldwide
Sisomicin sulfate (2:5) Sisomicin Sulfate is an aminoglycoside antibiotic produced by the strain of Micromonospora inyoensis NRRL 3292. It has a broad-spectrum antibacterial effects against Gram-positive and Gram-negative bacteria. Uses: Anti-bacterial agents. Synonyms: D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1→4)]-2-deoxy-, sulfate (2:5); D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-D-glycero-hex-4-enopyranosyl-(1→4)]-2-deoxy-, sulfate (2:5) (salt); Antibiotic 66-40 sulfate; Baymicin; Extramycin; Mensiso; Sisobiotic; Sisolline; Sisomicin sulfate; Sisomin; Sisomycin sulfate; Sissomicin sulfate. Grade: ≥95%. CAS No. 53179-09-2. Molecular formula: C19H37N5O7.5/2H2O4S. Mole weight: 1385.44. BOC Sciences
S-Isopropylisothiourea hydrobromide S-Isopropylisothiourea hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 4269-97-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 13
Worldwide
Sissotrin Sissotrin (Biochanin A 7-glucoside) has potent antimicrobial and antioxidant activities. Sissotrin is active against the yeasts and Gram-positive and Gram-negative bacteria with MICs of 32-256 μg/mL[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Biochanin A 7-glucoside; Sissonin. CAS No. 5928-26-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N1240. MedChemExpress MCE
Sissotrin Sissotrin is a natural flavonoid isolated from the herbs of Trifolium pratense L. It can impair glucose tolerance. Synonyms: Biochanin A-beta-D-glucoside. Grade: >98%. CAS No. 5928-26-7. Molecular formula: C22H22O10. Mole weight: 446.4. BOC Sciences 9

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