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Sisunatovir (RV521) is a potent and orally active respiratory syncytial virus (RSV) inhibitor with IC50 values of 1.4, 1.0 nM for RSV A, RSV B, respectively. Sisunatovir inhibits RSV infection and reduces virus titers in the lungs of mice[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RV521. CAS No. 1903763-82-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123475.
Sisunatovir hydrochloride
Sisunatovir (RV521) hydrochloride is a potent and orally active respiratory syncytial virus (RSV) inhibitor with IC50 values of 1.4, 1.0 nM for RSV A, RSV B, respectively. Sisunatovir hydrochloride inhibits RSV infection and reduces virus titers in the lungs of mice[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RV521 hydrochloride. CAS No. 1903763-83-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123475A.
Sitafloxacin
Sitafloxacin (Sitafloxacin anhydrous) is an orally active fluoroquinolone antibiotic with broad-spectrum antimicrobial activity.Sitafloxacin has been used in the study of respiratory tract infections and urinary tract infections. Category: Active pharmaceutical ingredients. CAS No. 127254-12-0. Product ID: API127254120. Molecular formula: C19H18ClF2N3O3. Mole weight: 409.81.
Sitafloxacin
Sitafloxacin, a new-generation, broad-spectrum oral fluoroquinolone that is very active against many Gram-positive, Gram-negative and anaerobic clinical isolates, including strains resistant to other fluoroquinolones, was recently approved in Japan for the treatment of respiratory and urinary tract infections. In terms of clinical efficacy, oral sitafloxacin was noninferior to oral levofloxacin in the treatment of community-acquired pneumonia or an infectious exacerbation of chronic respiratory tract disease, noninferior to oral tosufloxacin in the treatment of community-acquired pneumonia, and noninferior to oral levofloxacin in the treatment of complicated urinary tract infections, according to the results of randomized, double-blind, multicentre, noninferiority trials. Noncomparative studies demonstrated the efficacy of oral sitafloxacin in otorhinolaryngological infections, urethritis in men, C. trachomatis-associated cervicitis in women and odontogenic infections. Synonyms: 7-((S)-7-amino-5-azaspiro[24]heptan-5-yl)-8-chloro-6-fluoro-1-((1R,2S)-2-fluorocyclopropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; DU 6859; DU-6859; DU6859; DU 6859A; DU-6859A; DU6859A; Sitafloxacin; Sitafloxacin hydrate, Sitafloxacin anhydrous, Trade name: Gracevit. Grade: >98%. CAS No. 127254-12-0. Molecular formula: C19H18ClF2N3O3. Mole weight: 409.81.
Sitafloxacin hydrate
Sitafloxacin (DU6859a) hydrate is an orally active fluoroquinolone antibiotic (antibiotic) with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. Sitafloxacin is used in the study of respiratory tract infections and urinary tract infections[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DU6859a hydrate. CAS No. 163253-35-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0395C.
Sitafloxacin Hydrate
Sitafloxacin Hydrate (DU-6859a) is a fluoroquinolone antibiotic that shows promise in the treatment of Buruli ulcer. Category: Active pharmaceutical ingredients. CAS No. 163253-35-8. Product ID: API163253358. Molecular formula: C19H18ClF2N3O3ยท3/2H2O. Mole weight: 436.84.
Sitafloxacin hydrochloride
Sitafloxacin hydrochloride (DU6859a), a potent fluoroquinolone antibiotic with oral activity, demonstrates antichlamydial activity and a broad antibacterial spectrum against gram-positive, gram-negative, and anaerobic bacteria, in addition to atypical pathogens. It is utilized in researching respiratory tract and urinary tract infections. Category: Active pharmaceutical ingredients. CAS No. 346607-37-2. Product ID: API346607372. Molecular formula: C19H19Cl2F2N3O3. Mole weight: 446.28.
Sitafloxacin Impurity 10
Sitafloxacin Impurity 10. Uses: For analytical and research use. Molecular formula: C16H13F3N2O. Mole weight: 338.29. Catalog: APB09790.
Sitafloxacin Impurity 14
Sitafloxacin Impurity 14. Uses: For analytical and research use. Molecular formula: C19H18F3N3O3. Mole weight: 393.37. Catalog: APB09792.
Sitafloxacin Impurity 15
Sitafloxacin Impurity 15. Uses: For analytical and research use. Molecular formula: C16H13F3N2O3. Mole weight: 338.29. Catalog: APB09791.
Sitafloxacin Impurity 16
Sitafloxacin Impurity 16. Uses: For analytical and research use. CAS No. 148693-51-0. Molecular formula: C16H15ClFN3O3. Mole weight: 351.76. Catalog: APB148693510.
Sitafloxacin Impurity 17
Sitafloxacin Impurity 17. Uses: For analytical and research use. Molecular formula: C19H19ClF2N4O2. Mole weight: 408.83. Catalog: APB09793.
Sitafloxacin Impurity 18
Sitafloxacin Impurity 18. Uses: For analytical and research use. CAS No. 127199-14-8. Molecular formula: C4H5FO2. Mole weight: 104.08. Catalog: APB127199148.
Sitafloxacin Impurity 19
Sitafloxacin Impurity 19. Uses: For analytical and research use. CAS No. 127199-16-0. Molecular formula: C8H14FNO2. Mole weight: 175.2. Catalog: APB127199160.
Sitafloxacin Impurity 20
Sitafloxacin Impurity 20. Uses: For analytical and research use. CAS No. 149404-98-8. Molecular formula: C3H6FN. Mole weight: 75.09. Catalog: APB149404988.
Sitafloxacin Impurity 21
Sitafloxacin Impurity 21. Uses: For analytical and research use. CAS No. 114152-96-4. Molecular formula: C3H7ClFN. Mole weight: 111.54. Catalog: APB114152964.
Sitafloxacin Impurity 22
Sitafloxacin Impurity 22. Uses: For analytical and research use. CAS No. 1638744-20-3. Molecular formula: C3H7ClFN. Mole weight: 111.54. Catalog: APB1638744203.
Sitafloxacin Impurity 23
Sitafloxacin Impurity 23. Uses: For analytical and research use. CAS No. 129306-06-5. Molecular formula: C13H14N2O2. Mole weight: 230.27. Catalog: APB129306065.
Sitafloxacin Impurity 24
Sitafloxacin Impurity 24. Uses: For analytical and research use. CAS No. 129306-07-6. Molecular formula: C13H18N2. Mole weight: 202.3. Catalog: APB129306076.
Sitafloxacin Impurity 25
Sitafloxacin Impurity 25. Uses: For analytical and research use. CAS No. 144282-35-9. Molecular formula: C13H18N2. Mole weight: 202.3. Catalog: APB144282359.
Sitafloxacin Impurity 26
Sitafloxacin Impurity 26. Uses: For analytical and research use. CAS No. 1432056-70-6. Molecular formula: C18H26N2O2. Mole weight: 302.42. Catalog: APB1432056706.
Sitafloxacin Impurity 27
Sitafloxacin Impurity 27. Uses: For analytical and research use. CAS No. 101513-77-3. Molecular formula: C7H2ClF3O2. Mole weight: 210.54. Catalog: APB101513773.
Sitafloxacin Impurity 28
Sitafloxacin Impurity 28. Uses: For analytical and research use. Molecular formula: C9H4ClF3O3. Mole weight: 252.57. Catalog: APB09795.
Sitafloxacin Impurity 29
Sitafloxacin Impurity 29. Uses: For analytical and research use. Molecular formula: C11H9F3O4. Mole weight: 262.18. Catalog: APB09794.
Sitafloxacin Impurity 30
Sitafloxacin Impurity 30. Uses: For analytical and research use. Molecular formula: C19H18ClF2N3O3. Mole weight: 409.82. Catalog: APB09797.
Sitafloxacin Impurity 31
Sitafloxacin Impurity 31. Uses: For analytical and research use. Molecular formula: C19H18ClF2N3O3. Mole weight: 409.82. Catalog: APB09796.
Sitafloxacin Impurity 32
Sitafloxacin Impurity 32. Uses: For analytical and research use. CAS No. 127254-10-8. Molecular formula: C19H18ClF2N3O3. Mole weight: 409.82. Catalog: APB127254108.
Sitafloxacin Impurity 33
Sitafloxacin Impurity 33. Uses: For analytical and research use. CAS No. 127199-06-8. Molecular formula: C19H18ClF2N3O3. Mole weight: 409.82. Catalog: APB127199068.
Sitafloxacin Impurity 34
Sitafloxacin Impurity 34. Uses: For analytical and research use. Molecular formula: C12H8ClF2NO2. Mole weight: 271.65. Catalog: APB09798.
Sitafloxacin Impurity 35
Sitafloxacin Impurity 35. Uses: For analytical and research use. CAS No. 500569-52-8. Molecular formula: C19H19F2N3O3. Mole weight: 375.38. Catalog: APB500569528.
Sitafloxacin Impurity 36
Sitafloxacin Impurity 36. Uses: For analytical and research use. CAS No. 2365490-44-2. Molecular formula: C13H8ClF2NO4. Mole weight: 315.66. Catalog: APB2365490442.
Sitafloxacin Impurity 37
Sitafloxacin Impurity 37. Uses: For analytical and research use. Molecular formula: C13H9ClF2N2O3. Mole weight: 314.67. Catalog: APB09799.
Sitafloxacin Impurity 38
Sitafloxacin Impurity 38. Uses: For analytical and research use. Molecular formula: C16H16FN3O3. Mole weight: 317.32. Catalog: APB09800.
Sitafloxacin Impurity 40
Sitafloxacin Impurity 40. Uses: For analytical and research use. Molecular formula: C19H19F2N3O4. Mole weight: 391.37. Catalog: APB09801.
Sitafloxacin Impurity 41
Sitafloxacin Impurity 41. Uses: For analytical and research use. CAS No. 500295-84-1. Molecular formula: C19H19F2N3O4. Mole weight: 391.37. Catalog: APB500295841.
Sitafloxacin Impurity 42
Sitafloxacin Impurity 42. Uses: For analytical and research use. Molecular formula: C18H18ClF2N3O2. Mole weight: 381.81. Catalog: APB09802.
Sitafloxacin Impurity 7
Sitafloxacin Impurity 7. Uses: For analytical and research use. Molecular formula: C5H8FNO. Mole weight: 117.12. Catalog: APB09788.
Sitafloxacin Impurity 8
Sitafloxacin Impurity 8. Uses: For analytical and research use. CAS No. 129306-12-3. Molecular formula: C6H12N2. Mole weight: 112.18. Catalog: APB129306123.
Sitafloxacin Impurity 9
Sitafloxacin Impurity 9. Uses: For analytical and research use. CAS No. 144216-11-5. Molecular formula: C10H5F2NO3. Mole weight: 225.15. Catalog: APB144216115.
Sitafloxacin Impurity A
Sitafloxacin Impurity A. Uses: For analytical and research use. CAS No. 500295-83-0. Molecular formula: C16H16FN3O3. Mole weight: 317.32. Catalog: APB500295830.
Sitafloxacin Impurity P-1
Sitafloxacin Impurity P-1. Uses: For analytical and research use. CAS No. 2044706-49-0. Molecular formula: C16H17ClFN3O3. Mole weight: 353.78. Catalog: APB2044706490.
Sitafloxacin isomer II
Sitafloxacin isomer II. Group: Biochemicals. Grades: Highly Purified. CAS No. 127199-06-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. US Biological Life Sciences.
Worldwide
Sitafloxacin isomer I (SSR)
Sitafloxacin isomer I (SSR). Group: Biochemicals. Grades: Highly Purified. CAS No. 127254-11-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. US Biological Life Sciences.
Worldwide
Sitafloxacin monohydrate
Sitafloxacin (DU6859a) monohydrate is a potent oral fluoroquinolone antibiotic with antichlamydial and broad-spectrum antibacterial activities against gram-positive, gram-negative, anaerobic bacteria, and atypical pathogens, effective in researching respiratory and urinary tract infections. Category: Active pharmaceutical ingredients. CAS No. 163253-37-0. Product ID: API163253370. Molecular formula: C19H20ClF2N3O4. Mole weight: 427.83.
Sitaglipin Phosphate Impurity 7
Sitaglipin Phosphate Impurity 7. Uses: For analytical and research use. Molecular formula: C17H16F6N6O2. Mole weight: 450.35. Catalog: APB09564.
Sitaglipin Phosphate Impurity 8
Sitaglipin Phosphate Impurity 8. Uses: For analytical and research use. Molecular formula: C17H15F6N5O2. Mole weight: 435.33. Catalog: APB09565.
Sitagliptin
Sitagliptin (MK0431), a new oral hypoglycemic (anti-diabetic drug), is a new dipeptidyl peptidase-4 (DPP-4) inhibitor. This enzyme-inhibiting drug is used either alone or in combination with metformin or thiazolidinedione for treatment of type 2 diabetes mellitus. Category: Active pharmaceutical ingredients. CAS No. 486460-32-6. Product ID: API486460326. Molecular formula: C16H15F6N5O. Mole weight: 407.31.
Sitagliptin
Sitagliptin (MK-0431) is an oral and highly selective DPP-4 inhibitor with an IC50 of 18 nM. It is used for the treatment of type 2 diabetes. Group: Inhibitors. Alternative Names: MK-0431. CAS No. 486460-32-6. Pack Sizes: 25mg. Product ID: S5079. Formula: C16H15F6N5O. Smiles: C1CN2C(=NN=C2C(F)(F)F)CN1C(=O)CC(CC3=CC(=C(C=C3F)F)F)N. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Sitagliptin
Sitagliptin. Group: Biochemicals. Alternative Names: (3R)-3-Amino-1-[3-(trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4- triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one. Grades: Highly Purified. CAS No. 486460-32-6. Pack Sizes: 5g, 10g, 25g. Molecular Formula: C16H15F6N5O, Molecular Weight: 407.31. US Biological Life Sciences.
Worldwide
Sitagliptin
Sitagliptin (MK 0431) is a potent inhibitor of DPP4 with IC50 of 19 nM in Caco-2 cell extracts. Sitagliptin is used as a hypoglycemic agent to treat type 2 diabetes. Uses: The treatment of type 2 diabetes. Synonyms: 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine; MK0431; Xelevia; Januvia; Tesavel; NSC813215; (3R)-3-Amino-1-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-1-butanone; 1,2,4-triazolo[4,3-a]pyrazine-7(8H)-propanamine, 5,6-dihydro-γ-oxo-3-(trifluoromethyl)-α-[(2,4,5-trifluorophenyl)methyl]-, (αR)-. Grade: >98%. CAS No. 486460-32-6. Molecular formula: C16H15N5OF6. Mole weight: 407.31.
Sitagliptin
Sitagliptin (MK-0431) is an orally active and highly selective DPP4 inhibitor with an IC50 value of 19 nM. Sitagliptin blocks the degradation of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) by competing inhibition mechanism (K? = 1 nM), thereby increasing the level of active incretin. Sitagliptin can also directly stimulate the secretion of GLP-1 by intestinal L cells by activating the cAMP/PKA and ERK1/2 pathways, and this effect is independent of DPP-4. Sitagliptin shows protective effects on pancreatic islet grafts in 1-type diabetes models. Sitagliptin can be used for the study of 1-type and 2-type diabetes[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-0431. CAS No. 486460-32-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg. Product ID: HY-13749.
Sitagliptin-Butanoic Impurity
Sitagliptin-Butanoic Impurity. Uses: For analytical and research use. CAS No. 936630-57-8. Molecular formula: C10H10F3NO2. Mole weight: 233.19. Catalog: APB936630578.
Sitagliptin Carbamoyl β-D-Glucuronide
A metabolite of Sitagliptin. Group: Biochemicals. Alternative Names: 1- [N- [ (1R) -3- [5, 6-Dihydro-3- (trifluoromethyl) -1, 2, 4-triazolo [4, 3-a] pyrazin-7 (8H) -yl] -3-oxo-1- [ (2, 4, 5-trifluorophenyl) methyl] propyl] carbamate]. Grades: Highly Purified. CAS No. 940002-59-5. Pack Sizes: 1mg. US Biological Life Sciences.
An isotope labelled Sitagliptin. Sitagliptin, marketed as the phosphate salt, is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: (3R)-3-amino-1-[3-(trifluoromethyl)(5,5,6,6-D4)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one; (R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine D4. Grade: >98%. CAS No. 1426173-93-4. Molecular formula: C16H11D4F6N5O. Mole weight: 411.34.
Sitagliptin-d4 Phosphate
A trizolopyrazine dipeptidyl peptidase IV inhibitor. It has recently been approved for the therapy of type II diabetes. Group: Biochemicals. Alternative Names: 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazine-d4 Phosphate; Januvia-d4;MK 0431-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Sitagliptin Defluoro Impurity
Sitagliptin Defluoro Impurity. Uses: For analytical and research use. CAS No. 1824443-71-1. Molecular formula: C15H19F2NO4. Mole weight: 315.32. Catalog: APB1824443711.
Sitagliptin Dimer Impurity
Sitagliptin Dimer Impurity. Uses: For analytical and research use. CAS No. 2379621-81-3. Molecular formula: C25H26F6N2O5. Mole weight: 548.48. Catalog: APB2379621813.
Sitagliptin EP Impurity A
Sitagliptin EP Impurity A. Uses: For analytical and research use. CAS No. 823817-55-6. Molecular formula: C16H15F6N5O. Mole weight: 407.31. Catalog: APB823817556.
Sitagliptin EP Impurity A HCl
Sitagliptin EP Impurity A HCl. Uses: For analytical and research use. Molecular formula: C16H17ClF5N5O. Mole weight: 425.79. Catalog: APB09566.
Sitagliptin EP Impurity A Phosphate
Sitagliptin EP Impurity A Phosphate. Uses: For analytical and research use. CAS No. 823817-58-9. Molecular formula: C16H18F6N5O5P. Mole weight: 503.29. Catalog: APB823817589.
Sitagliptin EP Impurity B
Sitagliptin EP Impurity B. Uses: For analytical and research use. CAS No. 486460-31-5. Molecular formula: C16H16F5N5O. Mole weight: 389.33. Catalog: APB486460315.
Sitagliptin EP Impurity B HCl
Sitagliptin EP Impurity B HCl. Uses: For analytical and research use. CAS No. 486459-70-5. Molecular formula: C16H17ClF5N5O. Mole weight: 425.79. Catalog: APB486459705.
Sitagliptin EP Impurity B Phosphate
Sitagliptin EP Impurity B Phosphate. Uses: For analytical and research use. CAS No. 1345822-87-8. Molecular formula: C16H19F5N5O5P. Mole weight: 487.32. Catalog: APB1345822878.
Sitagliptin EP Impurity C
Sitagliptin EP Impurity C. Uses: For analytical and research use. CAS No. 945261-48-3. Molecular formula: C16H16F5N5O. Mole weight: 389.33. Catalog: APB945261483.
Sitagliptin EP Impurity C Phosphate
Sitagliptin EP Impurity C Phosphate. Uses: For analytical and research use. CAS No. 1345822-86-7. Molecular formula: C16H19F5N5O5P. Mole weight: 487.32. Catalog: APB1345822867.
Sitagliptin fenilalanil
Sitagliptin fenilalanil is a dipeptidyl aminopeptidase (DPP-4) inhibitor. Category: Active pharmaceutical ingredients. CAS No. 1339955-03-1. Product ID: API1339955031. Molecular formula: C25H24F6N6O2. Mole weight: 554.49.
Sitagliptin fenilalanil hydrochloride
Sitagliptin phenylalanine hydrochloride, a dipeptidyl peptidase-4 (DPP-4) inhibitor, is a chemical compound utilized in medical applications. Category: Active pharmaceutical ingredients. CAS No. 1339954-75-4. Product ID: API1339954754. Molecular formula: C25H25ClF6N6O2. Mole weight: 590.95.
Sitagliptin FP Impurity E Hydrochloride
Sitagliptin EP Impurity E is an impurity of Sitagliptin. Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor for treatment of diabetes mellitus type 2. Synonyms: Sitagliptin Impurity 17 HCl; Sitagliptin Acid Impurity HCl; (R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic Acid Hydrochloride; (βR)-β-Amino-2,4,5-trifluorobenzenebutanoic Acid Hydrochloride. Grade: >95%. CAS No. 1204818-19-8. Molecular formula: C10H11ClF3NO2. Mole weight: 269.65.