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| Product | Description | |
|---|---|---|
| Trospium Chloride | Tropine derivative with anticholinergic activity. Antispasmodic; used in treatment of urinary incontinence. Group: Biochemicals. Alternative Names: (1α,3 β , 5α )-3-[(2-Hydroxy-2, 2-diphenylacetyl)oxy]-spiro[8-azoniabicyclo[3. 2. 1]octane-8, 1'-pyrrolidinium] Chloride; Azoniaspiro; Keptan; Relaspium; Sanctura; Spasmex; Spasmo 3. Grades: Highly Purified. CAS No. 10405-02-4. Pack Sizes: 25mg. US Biological Life Sciences. |  Worldwide |
| Trospium chloride Related Compound B | Trospium chloride Related Compound B. Uses: For analytical and research use. CAS No. 63516-30-3. Mole weight: 373.87. Catalog: AP63516303. |  |
| Trospium chloride Related Compound C | Trospium chloride Related Compound C. Uses: For analytical and research use. CAS No. 3464-71-9. Mole weight: 217.74. Catalog: AP3464719. | |
| Trospium chloride (Standard) | Trospium (chloride) (Standard) is the analytical standard of Trospium (chloride). This product is intended for research and analytical applications. Trospium chloride is an orally active, specific and competitive antagonist of muscarinic cholinergic receptors (mAChRs), with antimuscarinic activity. Trospium chloride binds to muscarinic receptors M1, M2 and M3 with high affinity, but not nicotinic, cholinergic receptors[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 10405-02-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0461R. |  |
| Trospium-[d8] chloride | Trospium-[d8] chloride is the labelled analogue of Trospium Chloride, which is a derivative of tropine with anticholinergic property and could be used in the treatment of urinary incontinence as an antispasmodic. Synonyms: Trospium-d8 chloride. Molecular formula: C25H22D8ClNO3. Mole weight: 436.01. |  |
| Trotabresib | CC-90010 (compound 1) is a reversible and orally active BET inhibitor. CC-90010 is applied in the study for advanced solid tumors[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CC-90010. CAS No. 1706738-98-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137573. | |
| Trovafloxacin | Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 147059-72-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0170. | |
| Trovafloxacin mesylate | Trovafloxacin mesylate is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive, Gram-negative and anaerobic organisms. Trovafloxacin mesylate blocks the DNA gyrase and topoisomerase IV activity. Trovafloxacin mesylate is also a potent, selective and orally active pannexin 1 channel (PANX1) inhibitor with an IC50 of 4 μM for PANX1 inward current. Trovafloxacin mesylate does not inhibit connexin 43 gap junction or PANX2. Trovafloxacin mesylate leads to dysregulated fragmentation of apoptotic cells by inhibiting PANX1[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 147059-75-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103399. | |
| Trovafloxacin Mesylate | Fluorinated quinolone antibacterial. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA. Group: Biochemicals. Alternative Names: 7-[(1α, 5α, 6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2, 4-difluorophenyl)-6-fluoro-1, 4-dihydro-4-oxo-1, 8-naphthyridine-3-carboxylic Acid Methanesulfonate; CP 99219; CP 99219-27; Trovafloxacin Methanesulfonate; Trovafloxacin Monomethanesulfonate; Trovan. Grades: Highly Purified. CAS No. 147059-75-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| TROX-1 | TROX-1 is a selective, orally active and brain-penetrant N-type calcium channel (Cav2.2) inhibitor with an IC50 value of 0.11 μM. TROX-1 exerts state-dependent and use-dependent inhibition, preferentially targets open/inactivated channels, blocks depolarization-associated calcium influx, and fully blocks calcium influx in rat dorsal root ganglion neurons. TROX-1 reverses inflammatory-induced hyperalgesia, nerve injury-induced allodynia. TROX-1 can be used for the research of pain[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1309601-26-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120751. | |
| Troxacitabine | Troxacitabine. Group: Biochemicals. Alternative Names: 4-Amino-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)pyrimidin-2(1H)-one. Grades: Highly Purified. CAS No. 145918-75-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C8H11N3O4. US Biological Life Sciences. | Worldwide |
| Troxerutin | Troxerutin. Group: Biochemicals. Alternative Names: 3',4',7-?[O-(2-???)]??. Grades: Plant Grade. CAS No. 7085-55-4. Pack Sizes: 20mg. Molecular Formula: C33H42O19, Molecular Weight: 742.674999999999. US Biological Life Sciences. | Worldwide |
| Troxerutin-[d12] | Labelled Troxerutin. For venous disorders treatment. Synonyms: 2-[3,4-Bis(2-hydroxethoxy)phenyl]-3-[[6-O-(6-O-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-7-(2-hydroxyethoxy)-4H-1-benzopyran-4-one-d12; 3,4,7-Tris(hydroxyethyl)rutin-d12; Posorutin-d12; Rufen-P4-d12; Ruven-d12 THR; Trioxyethylrutin-d12; Troxevazin-d12; Vastribil-d12; Veinamitol-d12; Veniten-d12; Venoruton P4-d12. Grade: >98%. Molecular formula: C33H30D12O19. Mole weight: 754.75. | |
| Troxerutin Impurity 1 | Troxerutin Impurity 1. Uses: For analytical and research use. CAS No. 6980-20-7. Molecular formula: C35H46O20. Mole weight: 786.73. Catalog: APB6980207. | |
| Troxerutin Impurity 10 | Troxerutin Impurity 10. Uses: For analytical and research use. CAS No. 72352-99-9. Molecular formula: C31H38O18. Mole weight: 698.63. Catalog: APB72352999. | |
| Troxerutin Impurity 11 | Troxerutin Impurity 11. Uses: For analytical and research use. CAS No. 125092-04-8. Molecular formula: C29H34O17. Mole weight: 654.57. Catalog: APB125092048. | |
| Troxerutin Impurity 13 | Troxerutin Impurity 13. Uses: For analytical and research use. CAS No. 50846-13-4. Molecular formula: C23H26O11. Mole weight: 478.45. Catalog: APB50846134. | |
| Troxerutin Impurity 14 | Troxerutin Impurity 14. Uses: For analytical and research use. CAS No. 23077-89-6. Molecular formula: C25H30O12. Mole weight: 522.5. Catalog: APB23077896. | |
| Troxerutin Impurity 15 | Troxerutin Impurity 15. Uses: For analytical and research use. CAS No. 23077-88-5. Molecular formula: C21H22O10. Mole weight: 434.4. Catalog: APB23077885. | |
| Troxerutin Impurity 2 | Troxerutin Impurity 2. Uses: For analytical and research use. CAS No. 862127-01-3. Molecular formula: C31H38O18. Mole weight: 698.63. Catalog: APB862127013. | |
| Troxerutin Impurity 3 | Troxerutin Impurity 3. Uses: For analytical and research use. CAS No. 13190-92-6. Molecular formula: C29H34O17. Mole weight: 654.57. Catalog: APB13190926. | |
| Troxerutin Impurity 4 | Troxerutin Impurity 4. Uses: For analytical and research use. CAS No. 13190-91-5. Molecular formula: C31H38O18. Mole weight: 698.63. Catalog: APB13190915. | |
| Troxerutin Impurity 5 | Troxerutin Impurity 5. Uses: For analytical and research use. Molecular formula: C35H46O20. Mole weight: 786.73. Catalog: APB12084. | |
| Troxerutin Impurity 6 | Troxerutin Impurity 6. Uses: For analytical and research use. Molecular formula: C35H46O20. Mole weight: 786.73. Catalog: APB12083. | |
| Troxerutin Impurity 7 | Troxerutin Impurity 7. Uses: For analytical and research use. CAS No. 13374-50-0. Molecular formula: C33H42O19. Mole weight: 742.68. Catalog: APB13374500. | |
| Troxerutin Impurity 8 | Troxerutin Impurity 8. Uses: For analytical and research use. CAS No. 23077-87-4. Molecular formula: C23H26O11. Mole weight: 478.45. Catalog: APB23077874. | |
| Troxerutin Impurity 9 | Troxerutin Impurity 9. Uses: For analytical and research use. CAS No. 23869-24-1. Molecular formula: C29H34O17. Mole weight: 654.57. Catalog: APB23869241. | |
| Troxipide | Troxipide. Group: Biochemicals. Grades: Highly Purified. CAS No. 99777-81-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C15H22N2O4. US Biological Life Sciences. | Worldwide |
| Trp-Arg | Tryptophanyl-arginine is a dipeptide composed of tryptophan and arginine. It is an incomplete breakdown product of protein digestion or protein catabolism. Synonyms: L-Arginine, L-tryptophyl-; tryptophanyl-arginine; L-tryptophyl-L-arginine; (S)-2-((S)-2-Amino-3-(1H-indol-3-yl)propanamido)-5-guanidinopentanoic acid. Grade: ≥95% by HPLC. CAS No. 88831-09-8. Molecular formula: C17H24N6O3. Mole weight: 360.41. | |
| TRPC6-PAM-C20 | TRPC6-PAM-C20 is a selective positive allosteric modulator (PAM) of TRPC6 channels. TRPC6-PAM-C20 is a potent enhancer of channel activation, enabling low basal concentrations of DAG to induce activation of the ion channel. TRPC6-PAM-C20 induces increases in intracellular Ca2+ concentrations ([Ca2+]i) in TRPC6-expressing HEK293 cells with an EC50 of 2.37 μM. TRPC6-PAM-C20 can be used as a valuable tool to selectively exaggerate TRPC6-dependent signals[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 667427-75-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-136190. | |
| Trp-Gly-Gly-OH | Trp-Gly-Gly-OH. Synonyms: L-Tryptophylglycylglycinep; (S)-2-(2-(2-amino-3-(1H-indol-3-yl)propanamido)acetamido)acetic acid; Trp Gly Gly OH. Grade: ≥ 99% (TLC). CAS No. 20762-31-6. Molecular formula: C15H18N4O4. Mole weight: 318.33. | |
| Trp-Gly-Gly-OH | Trp-Gly-Gly-OH. Group: Biochemicals. Alternative Names: L-Tryptophyl glycyl glycine. Grades: Highly Purified. CAS No. 20762-31-6. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| Trp-Gly-Gly-OH 99+% (TLC) | Trp-Gly-Gly-OH 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 20762-31-6. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| Trp-His-Trp-Leu-Gln-Leu | Trp-His-Trp-Leu-Gln-Leu. Synonyms: α1-Mating factor fragment 1-6. CAS No. 65418-88-4. Molecular formula: C45H59N11O8. Mole weight: 882.02. | |
| TRPM4-IN-1 | TRPM4-IN-1 (CBA) is a potent and selective inhibitor of the cation channel TRPM4, with an IC50 of 1.5 μM. TRPM4-IN-1 can be used for the research of cardiac diseases and prostate cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CBA. CAS No. 351424-20-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122605. | |
| TRPM4-IN-2 | TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibitor with an IC50 value of 0.16 μM. TRPM4-IN-2 can be used for researching prostate cancer and colorectal cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NBA. CAS No. 667411-04-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-128172. | |
| TRPM8-IN-1 | TRPM8-IN-1 (example 14) is an inhibitor of transient receptor potential melastatin-8 (TRPM8) channels, IC50<5 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1159996-20-9. Pack Sizes: 2 mg. Product ID: HY-108461. | |
| Trp-Met | Trp-Met. Synonyms: L-Methionine, L-tryptophyl-; Tryptophanyl-methionine; L-Tryptophanyl-L-methionine; (S)-2-((S)-2-Amino-3-(1H-indol-3-yl)propanamido)-4-(methylthio)butanoic acid. CAS No. 21438-63-1. Molecular formula: C16H21N3O3S. Mole weight: 335.42. | |
| Trp-Trp | Trp-Trp. Synonyms: l-tryptophyl-l-tryptophan; L-Tryptophan, L-tryptophyl-; N-L-Tryptophyl-L-tryptophan; Tryptophyl-Tryptophan; L-Trp-L-Trp-OH; (S)-2-[(S)-2-Amino-3-(1H-indol-3-yl)-propionylamino]-3-(1H-indol-3-yl)-propionic acid. CAS No. 20696-60-0. Molecular formula: C22H22N4O3. Mole weight: 390.44. | |
| TRPV1 C- terminal Antibody [G12G6] | TRPV1,Vanilloid R1/TRPV1. Group: Antibodies. Alternative Names: TRPV1,Vanilloid R1. Pack Sizes: 20uL. Product ID: F2733. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| TRPV2-selective blocker 1 | TRPV2-selective blocker 1 is a TRPV2-selective blocker that inhibits calcium influx and ionic currents. TRPV2-selective blocker 1 exhibits an IC50 of 6.3 μM against rat TRPV2, and shows no activity against TRPV1, TRPV3 or TRPV4 channels. TRPV2-selective blocker 1 attenuates macrophage phagocytosis, LPS-induced macrophage migration, and calcium microdomains generated by peripheral TRPV2. TRPV2-selective blocker 1 is non-cytotoxic and can be used to investigate the function of TRPV2 during immune processes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2242724-49-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-157131. | |
| TRPV3 antagonist 74a | TRPV3 antagonist 74a is a potent and selective TRPV3 antagonist. TRPV3 antagonist 74a displays no significant activity against a panel of other ion channels. TRPV3 antagonist 74a can be used for the research of neuropathic pain[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1432051-63-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131868. | |
| Trt-Cysteamine HCl | S-Tritylcysteamine Hydrochloride has been shown to have an antileukemic activity. Synonyms: 2-tritylsulfanylethanamine,hydrochloride; S-tritylcysteamine HCl; S-trityl-D-cysteine; S-tritylcysteamine hydrochloride; S-trityl-2-mercaptoethylamine hydrochloride. Grade: ≥ 95%. CAS No. 15297-43-5. Molecular formula: C21H21NS·HCl. Mole weight: 355.92. | |
| Trt-cysteamine hydrochloride | Trt-cysteamine hydrochloride. Group: Biochemicals. Alternative Names: 2-(Tritylthio)ethylamine hydrochloride. Grades: Highly Purified. CAS No. 15297-43-5. Pack Sizes: 1g, 2g, 5g. US Biological Life Sciences. | Worldwide |
| Trt-cysteamine hydrochloride 99+% (HPLC) | Trt-cysteamine hydrochloride 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
| Trt-Trp-Ome | Trt-Trp-Ome. Synonyms: methyl trityl-L-tryptophanate. CAS No. 18598-78-2. Molecular formula: C31H28N2O2. Mole weight: 460.58. | |
| Tru9 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 65°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. T↑TAA AAT↓T. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer W. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned Tru9 I gene from Thermus ruber 9. Pack: 10 mM Tris-HCl-(pH 7.5); 50 mM NaCl; 0,1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1183RE. |  |
| True Blue | True Blue (NCI 240899) is a fluorescent dye, as neuronal retrograde tracer (excitation wavelength 395-425 nm, barrier filter 450 nm). True Blue can label neuron and has no effects on neuronal survival[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NCI 240899. CAS No. 71431-30-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D1161. | |
| True Blue Diaceturate Salt | True Blue Diaceturate Salt is a fluorescent neuronal tracer. It is also a salt form of 2, 2- (1, 2-Ethene diyl ) bis [5-benzofurancarboximidam ide ] (CAS 65426-90-6) which can be used in biological study for identification of small moecule inhibitors of anthrax lethal factor. Group: Biochemicals. Alternative Names: 2, 2- (1, 2-Ethene diyl ) bis-5-benzofurancarboximidam ide compd. with N-Acetylglycine. Grades: Purified. CAS No. 108321-12-6. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??N?O? 2(C?H?NO?), Molecular Weight: 578.58. US Biological Life Sciences. | Worldwide |
| TRULI | TRULI (Lats-IN-1) is a potent and ATP-competitive inhibitor of Lats1 and Lats2 kinases. TRULI promotes Yap-dependent proliferation in postmitotic mammalian tissues[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Lats-IN-1. CAS No. 1424635-83-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138489. | |
| TRULI (Lats-IN-1) | TRULI inhibits both Lats1 and Lats2 with a IC50 of 0.2?nM, suppresses Yap phosphorylation, induces cell proliferation in several cell lines and tissues, and promotes the initial stages of proliferative regeneration of the sensory receptors in the inner ear. Group: Inhibitors. CAS No. 1424635-83-5. Pack Sizes: 5mg. Product ID: E1061. Formula: C18H14N4OS. Smiles: O=C(N=C1SC=CN1CC2=CC=CC=C2)C3=C[NH]C4=NC=CC=C34. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| Truncated plakophilin-2 (581-590) | Truncated plakophilin-2 (581-590) is a truncated fragment of plakophilin-2 which is expressed in skin and cardiac muscle, where it functions to link cadherins to intermediate filaments in the cytoskeleton. This peptide can be used in Ovarian carcinoma related research. | |
| Truxene | Truxene. Alternative Names: 5H-Diindeno(1,2-a:1',2'-c)fluorene, 10,15-dihydro-;5H-Tribenzo[a,f,k]trindene, 10,15-dihydro-;alpha-Truxene;Benzene, tribenzylene-;Truxen;TRUXENE;10,15-DIHYDRO-5H-DIINDENO(1,2-A-1',2'-C)FLUORENE;10,15-dihydro-5H-tribenzo[a,f,k]triindene. CAS No. 548-35-6. Molecular formula: C27H18. Mole weight: 342.4g/mol. IUPAC Name: heptacyclo[18.7.0.02,10.03,8.011,19.012,17.021,26]heptacosa-1,3,5,7,10,12,14,16,19,21,23,25-dodecaene. SMILES: C1C2=CC=CC=C2C3=C4CC5=CC=CC=C5C4=C6CC7=CC=CC=C7C6=C31. InChI: InChI=1S/C27H18/c1-4-10-19-16(7-1)13-22-25(19)23-14-17-8-3-6-12-21(17)27(23)24-15-18-9-2-5-11-20(18)26(22)24/h1-12H,13-15H2. |  |
| Truxene, ≥98% | Truxene, ≥98%. CAS No. 548-35-6. Molecular formula: C27H18. Mole weight: 342.4g/mol. IUPAC Name: heptacyclo[18.7.0.02,10.03,8.011,19.012,17.021,26]heptacosa-1,3,5,7,10,12,14,16,19,21,23,25-dodecaene. SMILES: C1C2=CC=CC=C2C3=C4CC5=CC=CC=C5C4=C6CC7=CC=CC=C7C6=C31. InChI: InChI=1S/C27H18/c1-4-10-19-16(7-1)13-22-25(19)23-14-17-8-3-6-12-21(17)27(23)24-15-18-9-2-5-11-20(18)26(22)24/h1-12H,13-15H2. | |
| Truxenone | Truxenone. CAS No. 4430-15-3. Molecular formula: C27H12O3. Mole weight: 384.4g/mol. IUPAC Name: heptacyclo[18.7.0.02,10.03,8.011,19.012,17.021,26]heptacosa-1(20),2(10),3,5,7,11(19),12,14,16,21,23,25-dodecaene-9,18,27-trione. SMILES: C1=CC=C2C(=C1)C3=C(C2=O)C4=C(C5=C3C(=O)C6=CC=CC=C65)C(=O)C7=CC=CC=C74. InChI: InChI=1S/C27H12O3/c28-25-16-10-4-1-7-13(16)19-22(25)20-15-9-3-6-12-18(15)27(30)24(20)21-14-8-2-5-11-17(14)26(29)23(19)21/h1-12H. | |
| TRV055 | TRV055 (TRV120055) is a G protein-biased agonist of angiotensin II type 1 receptors (AT1Rs). TRV120055 induces fibroblast proliferation, overexpression of collagen I and α-SMA, and stress fibre formation in human cardiac fibroblasts. TRV055 activates AT1 receptor/Gαq-mediated signaling pathways, upregulates TGF-β1 and p-ERK1/2. TRV055 induces collagen secretion in adult rat myofibroblasts at a level comparable to Ang II. TRV055 can be used to study the role of G protein-biased signaling of AT1Rs in regulating fibrotic responses[1] | |
| TRV-120027 | Synthetic analogue of endogenous peptide angiotensin II. An investigational drug for the treatment of heart failure and kidney disease. Synonyms: (2R)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]propanoic acid. CAS No. 1234510-46-3. Molecular formula: C43H67N13O10. Mole weight: 926.1. | |
| TRV-120027 | TRV120027, a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R), engages β-arrestins while blocking G-protein signaling[1]. TRV120027 induces acute catecholamine secretion through cation channel subfamily C3 (TRPC3) coupling, promotes the formation of a macromolecular complex composed of AT1R-β-arrestin-1-TRPC3-PLCγ at the plasma membrane. TRV120027 inhibits angiotensin II-mediated vasoconstriction and increases cardiomyocyte contractility. TRV120027 has the potential for the acute decompensated heart failure (ADHF) treatment[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TRV027. CAS No. 1234510-46-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2141. | |
| TRV-120027 acetate | TRV-120027 acetate, a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R), engages β-arrestins while blocking G-protein signaling. TRV-120027 inhibits angiotensin II-mediated vasoconstriction and increases cardiomyocyte contractility. TRV-120027 has the potential for acute decompensated heart failure (ADHF) treatment. Synonyms: H-Sar-Arg-Val-Tyr-Ile-His-Pro-D-Ala-OH.CH3CO2H; sarcosyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-D-alanine acetic acid; D-Alanine, N-methylglycyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-, acetate (1:1); TRV 027 acetate; TRV 120027 acetate; TRV120027 acetate. Grade: ≥95%. Molecular formula: C45H71N13O12. Mole weight: 986.14. | |
| TRV-120027 TFA | TRV120027 TFA, a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R), engages β-arrestins while blocking G-protein signaling. TRV120027 TFA inhibits angiotensin II-mediated vasoconstriction and increases cardiomyocyte contractility. TRV120027 TFA has the potential for the acute decompensated heart failure (ADHF) treatment. Synonyms: H-Sar-Arg-Val-Tyr-Ile-His-Pro-D-Ala-OH.TFA; sarcosyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-D-alanine trifluoroacetate; D-Alanine, N-methylglycyl-L-arginyl-L-valyl-L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-, trifluoroacetate (1:1); TRV 027 trifluoroacetate; TRV 120027 trifluoroacetate; TRV120027 trifluoroacetate; TRV120027 TFA; TRV 120027 TFA. Grade: 99%. Molecular formula: C45H68F3N13O12. Mole weight: 1040.10. | |
| Trypacidin | It is produced by the strain of Aspergillus fumigatus. Trypacidin has anti-protozoal and spirochete effects, but the effect on the latter is weak. Synonyms: BRN 1299866; Methyl 4,6'-dimethoxy-6-methyl-3,4'-dioxo-3H-spiro[1-benzofuran-2,1'-cyclohexa[2,5]diene]-2'-carboxylate. Grade: ≥98% by HPLC. CAS No. 1900-29-4. Molecular formula: C18H16O7. Mole weight: 344.31. | |
| Trypan Blue (C.I.23850) | 25g Pack Size. Group: Analytical Reagents, Diagnostic Raw Materials, Stains & Indicators. Formula: C34H24N6O14S4Na4. CAS No. 72-57-1. Prepack ID 45660104-25g. Molecular Weight 960.8. See USA prepack pricing. |  |
| Trypanothione | Trypanothione is utilized as a substrate by trypanothione reductase, a unique enzyme found in trypanosomes and leishmanias (Km = 51 μM). Synonyms: Oxidized trypanothione; N(1),N(8)-Bis(gamma-glu-hemi-cys-gly)sperimidine; L-γ-Glutamyl-L-cysteinyl-N-[3-[[4-[[N-(N-L-γ-glutamyl-L-cysteinyl)glycyl]amino]butyl]amino]propyl]-glycinamide Cyclic (2→3)-disulfide; TS2. CAS No. 96304-42-6. Molecular formula: C27H47N9O10S2. Mole weight: 721.85. | |
| trypanothione-disulfide reductase | Trypanothione disulfide is the oxidized form of N1,N8-bis(glutathionyl)-spermidine from the insect-parasitic trypanosomatid Crithidia fasciculata. The enzyme from Crithidia fasciculata is a flavoprotein (FAD), whose activity is dependent on a redox-active cystine at the active centre. (cf. EC 1.8.1.7, glutathione-disulfide reductase). Group: Enzymes. Synonyms: trypanothione reductase; NADPH2:trypanothione oxidoreductase. Enzyme Commission Number: EC 1.8.1.12. CAS No. 102210-35-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1638; trypanothione-disulfide reductase; EC 1.8.1.12; 102210-35-5; trypanothione reductase; NADPH2:trypanothione oxidoreductase. Cat No: EXWM-1638. | |
| trypanothione synthase | The enzyme, characterized from several trypanosomatids (e.g. Trypanosoma cruzi) catalyses two subsequent reactions, leading to production of trypanothione from glutathione and spermidine. Some trypanosomatids (e.g. Crithidia species and some Leishmania species) also contain an enzyme that only carries out the first reaction (cf. EC 6.3.1.8, glutathionylspermidine synthase). The enzyme is bifunctional, and also catalyses the hydrolysis of glutathionylspermidine and trypanothione (cf. EC 3.5.1.78, glutathionylspermidine amidase). Group: Enzymes. Synonyms: glutathionylspermidine:glutathione ligase (ADP-forming). Enzyme Commission Number: EC 6.3.1.9. CAS No. 130246-69-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5729; trypanothione synthase; EC 6.3.1.9; 130246-69-4; glutathionylspermidine:glutathione ligase (ADP-forming). Cat No: EXWM-5729. | |
| Trypan red | Trypan red is a vital stain. Uses: Scientific research. Category: Signaling pathways. Alternative Names: C.I. 22850. CAS No. 574-64-1. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-D0983. | |
| Tryprostatin A | Tryprostatin A is a natural compound isolated from Aspergillus fumigatus and arrests cell cycle progression at the G2/M phase. Synonyms: (3S,8aS)-3-{[6-methoxy-2-(3-methylbut-2-en-1-yl)-1H-indol-3-yl]methyl}hexahydropyrrolo[1,2-a]pyrazine-1,4-dione. Grade: 98%. CAS No. 171864-80-5. Molecular formula: C22H27N3O3. Mole weight: 381.47. | |
| Tryprostatin B | Tryprostatin B is a natural compound isolated from Aspergillus fumigatus and arrests cell cycle progression at the G2/M phase. Synonyms: triprostatin B; (-)-Tryprostatin B; (3S,8aS)-3-{[2-(3-methylbut-2-en-1-yl)-1H-indol-3-yl]methyl}hexahydropyrrolo[1,2-a]pyrazine-1,4-dione. CAS No. 179936-52-8. Molecular formula: C21H25N3O2. Mole weight: 351.44. | |
| tryprostatin B 6-hydroxylase | A heme-thiolate protein (P-450). Involved in the biosynthetic pathways of several indole alkaloids such as tryprostatins, fumitremorgins and verruculogen. Group: Enzymes. Synonyms: ftmC (gene name). Enzyme Commission Number: EC 1.14.13.176. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0774; tryprostatin B 6-hydroxylase; EC 1.14.13.176; ftmC (gene name). Cat No: EXWM-0774. | |
| tryprostatin B synthase | The enzyme from the fungus Aspergillus fumigatus can also prenylate other tryptophan-containing cyclic dipeptides. Prenylation occurs mainly at C-2, but also at C-3. Involved in the biosynthetic pathways of several indole alkaloids such as tryprostatins, cyclotryprostatins, spirotryprostatins, fumitremorgins and verruculogen. Group: Enzymes. Synonyms: ftmPT1 (gene name); brevianamide F prenyltransferase (ambiguous). Enzyme Commission Number: EC 2.5.1.106. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2722; tryprostatin B synthase; EC 2.5.1.106; ftmPT1 (gene name); brevianamide F prenyltransferase (ambiguous). Cat No: EXWM-2722. | |
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