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| Product | Description | |
|---|---|---|
| Tth111 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (HindIII-digest) in 1 hour at 65°C in a total reaction volume of 50 μl. Applications: After 2-fold overdigestion with enzyme 10% of the dna fragments can be ligated. Group: Restriction Enzymes. Purity: 400U; 2000U. GACN↑NNGTC CTGNN↓NCAG. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries the cloned gene Tth111I from Thermus Thermophilus 111. Pack: 10 mM Tris-HCl (pH 7.5); 500 mM NaCl; 0,1 mM EDTA; 1 mM DTT; 50% glycerol. Cat No: ET-1185RE. |  |
| TTK21 | TTK21 is an activator of the histone acetyltransferases CBP/p300. TTK21 passes the blood-brain barrier, induces no toxicity, and reaches different parts of the brain when conjugated to glucose-based carbon nanosphere (CSP). TTK21 has beneficial implications for the brain functions of neurogenesis and long-term memory[1].CSP-TTK21 can ameliorate Aβ-impaired long-term potentiation (LTP). CSP-TTK21 may enhance the transcription of genes that promote synaptic health and cognitive function[2]. CSP-TTK21 is orally effective and leads to improvements in motor functions, histone acetylation dynamics in a spinal injury rat model[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 709676-56-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116673. |  |
| TTNPB | TTNPB is a highly potent RAR agonist. Competitive binding assays using human RARs yield IC50s of α=5.1 nM, β= 4.5 nM, and γ=9.3 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro 13-7410; Arotinoid acid; AGN191183. CAS No. 71441-28-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15682. | |
| TTNPB | TTNPB is a retinoic acid analog that selectively and potently activates the retinoic acid receptors. It is reported to increase the efficiency of induced pluripotent stem cell (iPSC) chemical reprogramming. Group: Biochemicals. Alternative Names: AGN-191183, Arotinoid acid, Arotinoic acid, Ro 13-7410; 4-[(E)-2-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)prop-1-enyl]benzoic acid. Grades: Purified. CAS No. 71441-28-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| TTNPB (Arotinoid acid) | TTNPB is a potent RAR agonist, and inhibits binding of [3H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively. Group: Inhibitors. Alternative Names: Arotinoid Acid, Ro 13-7410, AGN-191183. CAS No. 71441-28-6. Pack Sizes: 10mg. Product ID: S4627. Formula: C24H28O2. Smiles: CC(=CC1=CC=C(C=C1)C(=O)O)C2=CC3=C(C=C2)C(CCC3(C)C)(C)C. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| TTP 22 | TTP 22. Group: Biochemicals. Grades: Purified. CAS No. 329907-28-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| TTP-6171 | TTP-6171 is a non-covalent inhibitor of Monkeypox virus I7L protease, and it can be used for research on poxvirus infections[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 825647-78-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-147036. | |
| TTT-28 | TTT-28 is a synthesized thiazole-valine peptidomimetic, a novel selective inhibitor of ABCB1 (P-gp/MDR1) with high efficacy and low toxicity, which reverses the ATP-binding cassette sub-family B member 1 (ABCB1)-mediated multidrug resistance (MDR) by selectively blocking the efflux function of ABCB1[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1609138-51-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101511. | |
| t-TUCB | t-TUCB is a potent soluble epoxide hydrolase (sEH) inhibitor (IC50 = 0.9 nM) with anti-inflammatory and antinociceptive properties. It inhibits HSCs activation and reduces hepatic fibrosis by inhibiting NF-κB/IκBα signaling pathway. It enhances eNOS phosphorylation and NO release in the liver. It shows antihypertensive and cardioprotective effects in cirrhotic rat models. Alternative Names: UC-1728; trans-4-{4-[3-(4-Trifluoromethoxyphenyl)-ureido]cyclohexyloxy}benzoic acid; 4-(((1r,4r)-4-(3-(4-(trifluoromethoxy)phenyl)ureido)cyclohexyl)oxy)benzoic acid; 4-{[trans-4-({[4-(Trifluoromethoxy)phenyl]carbamoyl}amino)cyclohexyl]oxy}benzoic acid; Benzoic acid, 4-[[trans-4-[[[[4-(trifluoromethoxy)phenyl]amino]carbonyl]amino]cyclohexyl]oxy]-. Grades: ≥95%. CAS No. 948304-40-3. Molecular formula: C21H21F3N2O5. Mole weight: 438.40. |  |
| TTX-030 | TTX-030 is a humanized antibody expressed in CHO cells, targeting ENTPD1/CD39. TTX-030 contains huIgG4SP heavy chain and huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for TTX-030 can refer to Human IgG4 kappa, Isotype Control (HY-P99003). Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: Eltivutabart. CAS No. 2935496-38-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990670. | |
| Tu-AMP 1 | Tu-AMP 1 is an antimicrobial peptide isolated from Tulipa gesneriana L. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Alternative Names: Lys-Ser-Cys-Cys-Arg-Asn-Thr-Thr-Ala-Arg-Asn-Cys-Tyr-Asn-Val-Cys-Arg-Ile-Pro-Gly-Thr-Pro-Arg-Pro-Val-Cys-Ala-Ala-Thr-Cys-Asp-Cys-Lys-Leu-Ile-Thr-Gly-Thr-Lys-Cys-Pro-Pro-Gly-Tyr-Glu-Lys. | |
| Tu-AMP 2 | Tu-AMP 2 is an antimicrobial peptide isolated from Tulipa gesneriana L. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Alternative Names: Lys-Ser-Cys-Cys-Arg-Asn-Thr-Thr-Ala-Arg-Asn-Cys-Tyr-Asn-Val-Cys-Arg-Ile-Pro-Gly. | |
| Tubacin | Tubacin was used to study the role of HDAC6 in migration and invasion of bladder cancer cells. Tubacin (tubulin acetylation inducer) is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM. Uses: Histone deacetylase inhibitors. Alternative Names: rel-N1-(4-((2R,4R,6S)-4-(((4,5-Diphenyloxazol-2-yl)thio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-dioxan-2-yl)phenyl)-N8-hydroxyoctanediamide; Octanediamide, N1-(4-((2R,4R,6S)-4-(((4,5-diphenyl-2-oxazolyl)thio)methyl)-6-(4-(hydroxymethyl)phenyl)-1,3-dioxan-2-yl)phenyl)-N8-hydroxy-, rel-. Grades: ≥95%. CAS No. 537049-40-4. Molecular formula: C41H43N3O7S. Mole weight: 721.86. | |
| Tubacin | Tubacin (Tubulin acetylation inducer) is a highly potent, selective, reversible, and cell-permeable inhibitor of histone deacetylase 6 (HDAC6, IC50=4nm). Displays 1000-fold more selectivity for HDAC6 over other HDACs. It inhibits a-tubulin deacetylation in mammalian cells. Unlike trichostatin A (TSA), which is a broad spectrum HDAC inhibitor, tubacin is specific for the tubulin deacetylase activity of HDAC6. Tubacin causes increased acetylation of a-tubulin, accumulation of polyubiquitinated proteins, and apoptosis. It does not affect global histone deacetylation, gene-expression profiling, or cell cycle progression mediated a-tubulin deacetylation in mammalian cells. Group: Biochemicals. Alternative Names: (N-[4-[(2R,4R,6S)-4-[[(4,5-Diphenyl- 2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3- dioxan-2-yl]phenyl]-N'-hydroxyoctanediamide). Grades: Highly Purified. CAS No. 537049-40-4. Pack Sizes: 500ug, 1mg, 2.5mg. Molecular Formula: C??H??N?O?S, Molecular Weight: 721.86. US Biological Life Sciences. | Worldwide |
| Tubacin | Tubacin is a potent and selective inhibitor of HDAC6, with an IC50 value of 4 nM and approximately 350-fold selectivity over HDAC1. Tubacin also inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2). Uses: Scientific research. Category: Signaling pathways. CAS No. 537049-40-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13428. | |
| Tubastatin A | Tubastatin A is a potent and selective HDAC6 inhibitor with an IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A also inhibits HDAC10 and metallo-β-lactamase domain-containing protein 2 (MBLAC2). Uses: Scientific research. Category: Signaling pathways. CAS No. 1252003-15-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13271A. | |
| Tubastatin A | Tubastatin A is selective at all isozymes except HDAC8 and maintains over 1000-fold selectivity against all isoforms excluding HDAC8, where it has approximately 57-fold selectivity. Grades: >98%. CAS No. 1252003-15-8. Molecular formula: C20H21N3O2. Mole weight: 335.4. | |
| Tubastatin A | Tubastatin A is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay. It is selective against all the other isozymes (1000-fold) except HDAC8 (57-fold). Tubastatin A promotes autophagy and increases apoptosis. Group: Inhibitors. CAS No. 1252003-15-8. Pack Sizes: 50mg. Product ID: S8049. Formula: C20H21N3O2. Smiles: CN1CCC2=C(C1)C3=CC=CC=C3N2CC4=CC=C(C=C4)C(=O)NO. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Tubastatin A HCl salt | Tubastatin A is a potent and selective HDAC6 inhibitor. Tubastatin A was substantially more selective than the known HDAC6 inhibitor Tubacin at all isozymes except HDAC8. Tubastatin A is a potent HDAC6 inhibitor with an IC50 value of 15 nM. Tubastatin A induces α-tubulin hyperacetylation at 2.5 μM in primary cortical neuron cultures. In a model of oxidative stress induced by glutathione depletion, tubastatin A displays dose-dependent neuronal protection of primary cortical neuron cultures at 5-10 μM. Grades: 0.98. CAS No. 1310693-92-5. Molecular formula: C20H22ClN3O2. Mole weight: 371.865. | |
| Tubastatin A Hydrochloride | Tubastatin A Hydrochloride. Group: Biochemicals. Alternative Names: N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide Hydrochloride. Grades: Highly Purified. CAS No. 1310693-92-5. Pack Sizes: 10mg, 50mg, 100mg. Molecular Formula: C20H22ClN3O2, Molecular Weight: 371.86. US Biological Life Sciences. | Worldwide |
| Tubastatin A Hydrochloride | Tubastatin A Hydrochloride (Tubastatin A HCl) is a potent and selective HDAC6 inhibitor with IC50 of 15 nM in a cell-free assay, and is selective (1000-fold more) against all other isozymes except HDAC8 (57-fold more). Tubastatin A Hydrochloride also inhibits HDAC10 and metallo-β-lactamase domain-containing protein 2 (MBLAC2). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tubastatin A HCl; TSA HCl. CAS No. 1310693-92-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13271. | |
| Tubastatin A trifluoroacetate | Tubastatin A trifluoroacetate. Group: Biochemicals. Alternative Names: N-Hydroxy-4-[(1,2,3,4-tetrahydro-2-methyl-5H-pyrido[4,3-b]indol-5-yl)methyl]benzamide 2,2,2-trifluoroacetate. Grades: Highly Purified. CAS No. 1239262-52-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C22H22F3N3O4. US Biological Life Sciences. | Worldwide |
| Tubeimoside I | Tubeimoside I is an orally active HSPD1 inhibitor. Tubeimoside I inhibits NF-κB, MAPK, as well as regulates eNOS-VEGF. Tubeimoside I induces cytoprotective Autophagy via an Akt-mediated pathway. Tubeimoside I inhibits proinflammatory cytokine (IL-6 and IL-1β) production. Tubeimoside I exhibits anti-inflammatory activities. Tubeimoside I promotes angiogenesis and improves sepsis symptoms. Tubeimoside I is used in the research of inflammatory diseases, various cancers, sepsis and ischemic diseases[1][2][3][4][5][6][7][8][9][10][11]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tubeimoside-1; Lobatoside-H. CAS No. 102040-03-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0890. | |
| Tubeimoside I | Tubeimoside I. Group: Biochemicals. CAS No. 102040-03-9. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Tubeimoside III | Tubeimoside III. Group: Biochemicals. Grades: Plant Grade. CAS No. 115810-13-4. Pack Sizes: 20mg. Molecular Formula: C64H100O31, Molecular Weight: 1365.46. US Biological Life Sciences. | Worldwide |
| Tubeimoside I (Lobatoside H) | Tubeimoside I (Lobatoside H). Group: Biochemicals. Alternative Names: 3-[[2-O-[4-O- (4-Carboxy-3-hydroxy-3-methyl-1-oxobutyl-) -a-L-arabinopyranosyl]-b-D-glucopyranosyl]oxy]-2, 23-dihydroxy-28- (O-b-D-xylopyranosyl- (1-3) -O-6-deoxy-a-L-mannopyranosyl- (1-2) -a-L-arabinopyranosyl) ester; Lobatoside H. Grades: Plant Grade. CAS No. 102040-03-9. Pack Sizes: 20mg. Molecular Formula: C63H98O29, Molecular Weight: 1319.43. US Biological Life Sciences. | Worldwide |
| Tuberactinomycin A | Tuberactinomycin A is produced by the strain of Streptoverticillium griseoverticillatus var. tuberacticus B-386. It is effective against mycobacteria, but less effective against gram-positive and gram-negative bacteria. CAS No. 33103-21-8. Molecular formula: C25H43N13O11. Mole weight: 701.69. | |
| Tubercidin | Tubercidin (7-Deazaadenosine) is an antibiotic obtained from Streptomyces tubercidicus. Tubercidin inhibits the growth of Streptococcus faecalis (8043) with an IC50 of 0.02 μM[1]. Tubercidin inhibits polymerases by incorporating DNA or RNA, thereby inhibiting DNA replication, RNA and protein synthesis[2]. Tubercidin is a weak inhibitor of adenosine phosphorylase, and interferes with the phosphorylation of adenosine and AMP[1]. Tubercidin has antiviral activity[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 7-Deazaadenosine. CAS No. 69-33-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100126. | |
| Tubercidin | Tubercidin. Group: Biochemicals. Alternative Names: 4-Amino-7-( β -D-ribofuranosyl) pyrrolo[2, 3-d]pyrimidine; 6-Amino-9-D-ribofuranosyl-7-desazapurine; 7-Deazaadenosine; Antibiotic XK 101-1; N7-Deazaadenosine; NSC 5640Sparsamycin A; Sparsomycin A; Tubercidine; U 10071. Grades: Highly Purified. CAS No. 69-33-0. Pack Sizes: 10mg. Molecular Formula: C11H14N4O3, Molecular Weight: 250.25. US Biological Life Sciences. | Worldwide |
| Tubercidin | Tubercidin is an adenosine analog with antiviral, antitrypanosomal, and antifungal properties. It inhibits DNA/RNA synthesis and other metabolic processes. Uses: 7-deaza-adenosine is an adenosine analog. Alternative Names: 7-Deazaadenosine; Antibiotic XK 101-1; BRN 0038498; 7-Deaza ribo Adenosine; 7-β-D-Ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 4-Amino-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine; 6-Amino-9-D-ribofuranosyl-7-desazapurine; N7-Deazaadenosine; NQZ-003; NSC 56408; Sparsamycin A; Sparsomycin A; Tubercidine; U 10071. Grades: ≥98% by HPLC. CAS No. 69-33-0. Molecular formula: C11H14N4O4. Mole weight: 266.25. | |
| tubercidin 5'-triphosphate | tubercidin 5'-triphosphate. Alternative Names: tubercidin 5'-triphosphate. CAS No. 10058-66-9. Product ID: ACM10058669. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| tuberculosinol synthase | Only found in species of Mycobacterium that cause tuberculosis. In addition, it also gives isotuberculosinol in 1:1 mixture, cf. EC 3.1.7.9, isotuberculosinol synthase. Group: Enzymes. Synonyms: Rv3378c. Enzyme Commission Number: EC 3.1.7.8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3768; tuberculosinol synthase; EC 3.1.7.8; Rv3378c. Cat No: EXWM-3768. | |
| Tuberculosis inhibitor 3 | Tuberculosis inhibitor 3 shows potent anti-TB activity (MIC < 0.016 μg/mL) against drug-sensitive / resistant MTB strains. Grades: ≥98%. CAS No. 2219325-28-5. Molecular formula: C21H22F6N4O3S. Mole weight: 524.48. | |
| Tuberculostearic Acid | Tuberculostearic Acid. Alternative Names: 10-methyloctadecanoic acid. CAS No. 542-47-2. Purity: 95% ethanol. Product ID: ACM542472. Molecular formula: C19H38O2. Mole weight: 298.50. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Tuberin | Tuberin is produced by the strain of Str.amakusaensis 10-101 and it is resistant to mycobacteria. Alternative Names: N-Formyl-T-P-methoxystyrilamine; NSC 7382; N-trans-(p-Methoxystyryl)formamide. CAS No. 53643-53-1. Molecular formula: C10H11NO2. Mole weight: 177.20. | |
| Tubermycin B | A simple phenazine produced by several species of pseudomonas and actinomycetes. It is a weakly active antibacterial compound that plays a role in the biocontrol of plant diseases by several pseudomonas strains. Alternative Names: 1-Phenazinecarboxylic acid; 1-Carboxylic acid phenazine; NRRL B-1576; NSC 15851; BRN 0183818. Grades: >98% by HPLC. CAS No. 2538-68-3. Molecular formula: C13H8N2O2. Mole weight: 224.21. | |
| Tuberostemonine | Tuberstemonine, coming from the roots of Stemona japonica, exhibited relatively higher intestinal permeabilities. It acts in part as an open-channel blocker at the crayfish neuromuscular junction. Uses: Anti-inflammatory / anti-bacterial / anti-allergy. Alternative Names: (7aR,8aβ,11aβ,11bα,11cβ)-2β-[(2S,4S)-Tetrahydro-4-methyl-5-oxofuran-2-yl]-8β-ethyltetradecahydro-11β-methylfuro[2,3-h]pyrrolo[3,2,1-jk][1]benzoazepine-10-one; 2β-[(2S,4S)-Tetrahydro-4-methyl-5-oxofuran-2-yl]stenine; TUBERSTEMONINE(P). Grades: >98%. CAS No. 6879-1-2. Molecular formula: C22H33NO4. Mole weight: 375.51. | |
| Tuberostemonine | Tuberostemonine. Group: Biochemicals. Grades: Plant Grade. CAS No. 6879-1-2. Pack Sizes: 20mg. Molecular Formula: C22H33NO4, Molecular Weight: 375.5. US Biological Life Sciences. | Worldwide |
| Tuberostemonine Trifluoroacetate | Tuberostemonine Trifluoroacetate. Group: Biochemicals. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Tubocurarine Chloride Pentahydrate, 98% | Tubocurarine Chloride Pentahydrate, 98%. CAS No. 6989-98-6. Molecular formula: C37H52Cl2N2O11. Mole weight: 771.7g/mol. IUPAC Name: (1S,16R)-10,25-dimethoxy-15,15,30-trimethyl-7,23-dioxa-30-aza-15-azoniaheptacyclo[22.6.2.23,6.18,12.118,22.027,31.016,34]hexatriaconta-3(36),4,6(35),8(34),9,11,18(33),19,21,24,26,31-dodecaene-9,21-diol;chloride;pentahydrate;hydrochloride. SMILES: CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C6C(CC7=CC(=C(C=C7)O)O3)[N+](CCC6=CC(=C5O)OC)(C)C)OC.O.O.O.O.O.Cl.[Cl-]. InChI: InChI=1S/C37H40N2O6.2ClH.5H2O/c1-38-14-12-24-19-32(42-4)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-37-35-25(20-34(43-5)36(37)41)13-15-39(2,3)29(35)17-23-8-11-30(40)31(18-23)45-33;;;;;;;/h6-11,18-21,28-29H,12-17H2,1-5H3,(H-,40,41);2*1H;5*1H2/t28-,29+;;;;;;;/m0../s1. |  |
| Tubular Diagnostic Screw Neck Vials | Tubular Diagnostic Screw Neck Vials. Product ID: PM-032. Product Keywords: Packaging Materials; Glass Packaging; PM-032; Tubular Diagnostic Screw Neck Vials. |  |
| tubulin GTPase | An intrinsic activity of α-tubulin involved in tubulin folding, division plane formation in prokaryotic cells and others. Group: Enzymes. Enzyme Commission Number: EC 3.6.5.6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4717; tubulin GTPase; EC 3.6.5.6. Cat No: EXWM-4717. | |
| Tubulin inhibitor 30 | Tubulin inhibitor 30 (Compound 15) is a tubulin assembly inhibitor with an IC50 of 0.52 μM. Tubulin inhibitor 30 can induce ferroptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2873383-67-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151879. | |
| tubulin-tyrosine ligase | L-Tyrosine is linked via a peptide bond to the C-terminus of de-tyrosinated α-tubulin (des-Tyrω-α-tubulin). The enzyme is highly specific for α-tubulin and moderately specific for ATP and L-tyrosine. L-Phenylalanine and 3,4-dihydroxy-L-phenylalanine are transferred but with higher Km values. Group: Enzymes. Enzyme Commission Number: EC 6.3.2.25. CAS No. 60321-03-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5743; tubulin-tyrosine ligase; EC 6.3.2.25; 60321-03-1. Cat No: EXWM-5743. | |
| tubulinyl-Tyr carboxypeptidase | Active at neutral pH, from brain. Group: Enzymes. Synonyms: carboxypeptidase-tubulin; soluble carboxypeptidase; tubulin-tyrosine carboxypeptidase; tubulin carboxypeptidase; tubulinyltyrosine carboxypeptidase; tyrosinotubulin carboxypeptidase; tyrosyltubulin carboxypeptidase; TTCPase; brain I carboxypeptidase. Enzyme Commission Number: EC 3.4.17.17. CAS No. 73050-23-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4069; tubulinyl-Tyr carboxypeptidase; EC 3.4.17.17; 73050-23-4; carboxypeptidase-tubulin; soluble carboxypeptidase; tubulin-tyrosine carboxypeptidase; tubulin carboxypeptidase; tubulinyltyrosine carboxypeptidase; tyrosinotubulin carboxypeptidase; tyrosyltubulin carboxypeptidase; TTCPase; brain I carboxypeptidase. Cat No: EXWM-4069. | |
| Tubuloside A | Tubuloside A is a phenylethanoid glycoside with antioxidative effect and hepatoprotective activity. Alternative Names: Tubuloside A; 112516-05-9; [(2R,3R,4S,5R,6R)-5-acetyloxy-6-[2-(3,4-dihydroxyphenyl)ethoxy]-2-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate; SCHEMBL4044477; MFCD28251989; AKOS037514890; (2R,3R,4S,5R,6R)-5-(acetyloxy)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-2-({[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)-4-{[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-3-yl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate. Grades: >98%. CAS No. 112516-05-9. Molecular formula: C37H48O21. Mole weight: 828.76. | |
| Tubulysin | Tubulysin is a microtubule destabilizer that binds to the β-tubulin peptide site adjacent to the vinca alkaloid binding site and inhibits tubulin polymerization. Tubulysin induces apoptosis and exhibits antiproliferative activity against a variety of human cancer cells, including multidrug-resistant strains. Tubulysin can be conjugated to antibodies via a disulfide-containing quaternary ammonium linker for ADC synthesis. Tubulysin is applicable to tumor-related research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1943604-24-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-128914. | |
| Tubulysin A | Tubulysin A (TubA) is an anticancer and antiangiogenic agent with anti-microtubule, anti-mitosis and anti-proliferative activity against a variety of cancer cells with IC50 values in the pmol range. It can induce apoptosis of cancer cells and has no effect on normal cells. Tubulysins are a group of potent cytotoxins consisting of nine members (A-I). Tubulysin A can synthesize ADC as ADC Cytotoxin[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TubA. CAS No. 205304-86-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15995. | |
| Tubulysin A | Tubulysin A is a novel antibiotic, which exhibits anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative activity. Tubulysins show very high cytotoxic activity against in vitro and in in vivo tumor models, especially against resistant tumor cell lines. Many representatives of these natural products are several orders of magnitude more potent than other available chemotherapeutics. Uses: Adcs cytotoxin. Alternative Names: TubA; (αS,γR)-γ-[[[2-[(1R,3R)-1-(Acetyloxy)-4-methyl-3-[[(2S,3S)-3-methyl-2-[[[(2R)-1-methyl-2-piperidinyl]carbonyl]amino]-1-oxopentyl][(3-methyl-1-oxobutoxy)methyl]amino]pentyl]-4-thiazolyl]carbonyl]amino]-4-hydroxy-α-methyl-benzenepentanoic Acid. Grades: ≥95% by HPLC. CAS No. 205304-86-5. Molecular formula: C43H65N5O10S. Mole weight: 844.07. | |
| Tubulysin B | Tubulysin B is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates. It also has anti-fungal properties. Alternative Names: (2S,4R)-2-Methyl-4-[2-[(1R,3R)-1-acetoxy-3-[[N-[[(2R)-1-methyl-2beta-piperidinyl]carbonyl]-L-isoleucyl](butanoyloxymethyl)amino]-4-methylpentyl]thiazole-4-ylcarbonylamino]-5-(4-hydroxyphenyl)pentanoic acid. Grades: ≥95%. CAS No. 205304-87-6. Molecular formula: C42H63N5O10S. Mole weight: 830.04. | |
| Tubulysin C | Tubulysin C is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin C is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis. Alternative Names: Tubulysin C; 205304-88-7; 072P54KU0L; UNII-072P54KU0L; (2S,4R)-4-[[2-[(1R,3R)-1-acetyloxy-4-methyl-3-[[(2S,3S)-3-methyl-2-[[(2R)-1-methylpiperidine-2-carbonyl]amino]pentanoyl]-(propanoyloxymethyl)amino]pentyl]-1,3-thiazole-4-carbonyl]amino]-5-(4-hydroxyphenyl)-2-methylpentanoic acid; Benzenepentanoic acid, gamma-(((2-((1R,3R)-1-(acetyloxy)-4-methyl-3-(((2S,3S)-3-methyl-2-((((2R)-1-methyl-2-piperidinyl)carbonyl)amino)-1-oxopentyl)((1-oxopropoxy)methyl)amino)pentyl)-4-thiazolyl)carbonyl)amino)-4-hydroxy-alpha-methyl-, (alphaS. ga; SCHEMBL24218753; EX-A5466C; HY-N2347; AKOS040740942; CS-0021784; BENZENEPENTANOIC ACID. GAMMA.-(((2-((1R,3R)-1-(ACETYLOXY)-4-METHYL-3-(((2S,3S)-3-METHYL-2-((((2R)-1-METHYL-2-PIPERIDINYL)CARBONYL)AMINO)-1-OXOPENTYL)((1-OXOPROPOXY)METHYL)AMINO)PENTYL)-4-THIAZOLYL)CARBONYL)AMINO)-4-HYDROXY-.ALPHA.-METHYL-, (.ALPHA.S. GAMMA.R)-. Grades: 98%. CAS No. 205304-88-7. Molecular formula: C41H61N5O10S. Mole weight: 816.02. | |
| Tubulysin D | Tubulysin D is a tetrapeptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. It displays potent antitumor activity and leads to cell cycle arrest and apoptosis by inhibiting tubulin polymerization with an IC50 of 1.7 μM. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the lower nanomolar range. Alternative Names: (+)-Tubulysin D. Grades: ≥98%. CAS No. 309935-57-7. Molecular formula: C43H65N5O9S. Mole weight: 828.07. | |
| Tubulysin M | Tubulysin M is a highly cytotoxic anti-microtubule toxin (anti-microtubule toxins) that is synthesized as an ADC cytotoxin (ADC Cytotoxin). Tubulysin M can be isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis. Tubulysin M displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the low nanomolar range. Tubulysin M inhibits microtubule/tubulin polymerization and leads to cell cycle arrest and apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 936691-46-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7053. | |
| Tubulysin M | Tubulysin M is a Tubulysin D analog with potential anti-cancer properties, used as the cytotoxic component in antibody-drug conjugates. Alternative Names: (2S,4R)-4-{[(2-{(1R,3R)-1-Acetoxy-4-methyl-3-[methyl(N-{[(2R)-1-methyl-2-piperidinyl]carbonyl}-L-isoleucyl)amino]pentyl}-1,3-thiazol-4-yl)carbonyl]amino}-2-methyl-5-phenylpentanoic acid. Grades: ≥95%. CAS No. 936691-46-2. Molecular formula: C38H57N5O7S. Mole weight: 727.39. | |
| Tucaresol | Tucaresol is an orally bioavailable immunopotentiatory drug that show to enhance T-helper-cell activity, with the induction of increased IL-2 and IFN-γ levels in mice and humans. Tucaresol has anti-HIV effect[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BWA589C. CAS No. 84290-27-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106755. | |
| Tucatinib | Tucatinib (Irbinitinib) is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Irbinitinib; ARRY-380; ONT-380. CAS No. 937263-43-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16069. | |
| Tucatinib hemiethanolate | Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Irbinitinib hemiethanolate; ARRY-380 hemiethanolate; ONT-380 hemiethanolate. CAS No. 1429755-56-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16069A. | |
| Tucatinib Impurity 1 | Tucatinib Impurity 1. Uses: For analytical and research use. Molecular formula: C15H21N5O2S. Mole weight: 335.43. Catalog: APB12028. |  |
| Tucatinib Impurity 10 | Tucatinib Impurity 10. Uses: For analytical and research use. Molecular formula: C15H21N5O2. Mole weight: 303.37. Catalog: APB12035. | |
| Tucatinib Impurity 11 | Tucatinib Impurity 11. Uses: For analytical and research use. Molecular formula: C13H16N4O2S. Mole weight: 292.36. Catalog: APB12034. | |
| Tucatinib Impurity 12 | Tucatinib Impurity 12. Uses: For analytical and research use. Molecular formula: C24H22N8OS. Mole weight: 470.56. Catalog: APB12037. | |
| Tucatinib Impurity 13 | Tucatinib Impurity 13. Uses: For analytical and research use. Molecular formula: C27H22N8O3. Mole weight: 506.53. Catalog: APB12036. | |
| Tucatinib Impurity 14 | Tucatinib Impurity 14. Uses: For analytical and research use. Molecular formula: C26H24N8OS. Mole weight: 496.59. Catalog: APB12038. | |
| Tucatinib Impurity 2 | Tucatinib Impurity 2. Uses: For analytical and research use. CAS No. 937263-81-5. Molecular formula: C26H24N8O3. Mole weight: 496.53. Catalog: APB937263815. | |
| Tucatinib Impurity 3 | Tucatinib Impurity 3. Uses: For analytical and research use. CAS No. 937266-01-8. Molecular formula: C26H24N8OS. Mole weight: 496.59. Catalog: APB937266018. | |
| Tucatinib Impurity 4 | Tucatinib Impurity 4. Uses: For analytical and research use. CAS No. 2307628-67-5. Molecular formula: C21H17N7O. Mole weight: 383.42. Catalog: APB2307628675. | |
| Tucatinib Impurity 5 | Tucatinib Impurity 5. Uses: For analytical and research use. Molecular formula: C26H18D6N8O2. Mole weight: 486.57. Catalog: APB12029. | |
| Tucatinib Impurity 6 | Tucatinib Impurity 6. Uses: For analytical and research use. Molecular formula: C10H10N4O. Mole weight: 202.22. Catalog: APB12031. | |
| Tucatinib Impurity 7 | Tucatinib Impurity 7. Uses: For analytical and research use. Molecular formula: C21H22N8S. Mole weight: 418.52. Catalog: APB12030. | |
| Tucatinib Impurity 8 | Tucatinib Impurity 8. Uses: For analytical and research use. Molecular formula: C15H21N5O2S. Mole weight: 335.43. Catalog: APB12032. | |
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