A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Z-4-fluoro-L-phenylalanine chloromethylketone 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
Worldwide
Z-4-iodopiperidine
Z-4-iodopiperidine. Group: Biochemicals. Grades: Highly Purified. CAS No. 885275-00-3. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences.
Worldwide
Z-4-Oxo-D-Pro-Ome
Z-4-Oxo-D-Pro-Ome. Synonyms: Z 4 Oxo D Pro Ome. CAS No. 132431-11-9. Molecular formula: C14H15NO5. Mole weight: 277.27.
Z-4-Oxo-Pro-Ome
A building block used in the synthesis of dipeptidyl peptidase IV inhibitors and HIV integrase inhibitors. Synonyms: (S)-1-Benzyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate; (S)-L-benzyl-2-methyl 4-oxopyrrolidine-1,2-dicarboxylate. Grade: 95%. CAS No. 16217-15-5. Molecular formula: C14H15NO5. Mole weight: 277.27.
Z4P
Z4P is a BBB-penetrable IRE1 inhibitor with an IC50 of 1.13 μM. Z4P in combination with Temozolomide (HY-17364) inhibits the growth and recurrence of glioblastoma and has anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2361760-87-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153773.
Z57346765 is an inhibitor that targets the ADP-binding pocket of PGK1, with a Kd of 20.9 μM for human PGK1, and exhibits anticancer activity. Z57346765 reduces the activity of the metabolic enzyme PGK1 during glycolysis, regulates lipid peroxidation and cancer cell proliferation, and promotes lipid peroxidation in cervical cancer cells. Z57346765 inhibits the proliferation of cervical cancer and clear cell renal cell carcinoma cells in xenograft mouse models, and induces the expression of genes associated with cell metabolism, DNA replication and cell cycle. Z57346765 is used in research related to cervical cancer, clear cell renal cell carcinoma and breast cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1016340-64-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W195984.
Z62954982
Z62954982 (ZINC08010136) is a potent, selective and cell-permeable Rac1 (IC50=12 μM) inhibitor that is 4 times more effective than NSC23766 (HY-15723A) (IC50=50 μM). Z62954982 disrupts the Rac1/Tiam1 complex and decreases cytoplasmic levels of active Rac1 (GTP-bound Rac1), without affecting the activity of other Rho GTPases (such as Cdc42 or RhoA)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZINC08010136. CAS No. 1090893-12-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115376.
Z-6-aminohexanoic acid 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
Worldwide
Z-8-Amino-3,6-dioxaoctanoic acid dicyclohexylamine salt
Z-8-Amino-3,6-dioxaoctanoic acid dicyclohexylamine salt. Group: Biochemicals. Alternative Names: Z-AEEA.DCHA. Grades: Highly Purified. CAS No. 560088-84-8. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
Z-8-Amino-3,6-dioxaoctanoic acid dicyclohexylamine salt 99+% (HPLC)
Z-8-Amino-3,6-dioxaoctanoic acid dicyclohexylamine salt 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
Z907 Dye, 95%
Z907 Dye, 95%. CAS No. 502693-09-6.
ZA3-Ep10
ZA3-Ep10 is a zwitterionic lipid used in lipid nanoparticles formulation for in vivo RNA delivery. Uses: Scientific research. Category: Signaling pathways. CAS No. 2090299-48-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-145794.
Z-a-aminoisobutyric acid 99+%
Z-a-aminoisobutyric acid 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g. US Biological Life Sciences.
Worldwide
Zabadinostat
Zabadinostat (CXD101) is a potent, selective and orally active class I HDAC inhibitor with IC50s of 63 nM, 570 nM and 550 nM for HDAC1, HDAC2 and HDAC3, respectively. Zabadinostat has no activity against HDAC class II. Zabadinostat has antitumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CXD101. CAS No. 934828-12-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100748.
Zabedosertib
Zabedosertib (BAY 1834845) is a selective, orally active IRAK4 inhibitor with immunomodulatory potential, IC50 is 3.55 nM. IRAK4 is a protein kinase involved in signaling innate immune responses from Toll-like receptors[1]. Zabedosertib exhibits anti-inflammatory property against IL-β, LPS (HY-D1056) and Imiquimod (HY-B1080) induced inflammation[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY 1834845. CAS No. 1931994-81-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139374.
ZabofloxacinDW-224a Free base
Zabofloxacin is a potent and seletive bacterial type II and IV topoisomerases inhibitor, and has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia. Category: Active pharmaceutical ingredients. CAS No. 219680-11-2. Product ID: API219680112. Molecular formula: C19H20FN5O4. Mole weight: 401.39.
Zabofloxacin hydrochloride
Zabofloxacin hydrochloride is a potent and seletive bacterial type II and IV topoisomerases inhibitor, has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia. Category: Active pharmaceutical ingredients. CAS No. 623574-00-5. Product ID: API623574005. Molecular formula: C19H21ClFN5O4. Mole weight: 437.86.
Zabofloxacin hydrochloride
Zabofloxacin hydrochloride (DW-224a) is a potent and seletive inhibitor of the bacterial type II and IV topoisomerases. Zabofloxacin hydrochloride has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia. Zabofloxacin hydrochloride is a novel fluoronaphthyridone quinolone that is considered as an alternative antibiotic for treatment of quinolone-susceptible (QSSP) and quinolone-resistant gonorrhea (QRSP)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DW-224a. CAS No. 623574-00-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106410A.
PSMA I&T is an effective inhibitor of prostate-specific membrane antigen (PSMA). PSMA I&T can be used for SPECT/CT imaging and radionuclide studies in triple-negative breast cancer and prostate cancer (PCa)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PSMA I&T; PNT-2002. CAS No. 2192281-54-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148761.
Z-AEVD-FMK
Z-AEVD-FMK is a caspase-10 inhibitor. Z-AEVD-FMK can inhibit the activation of Bid and the release of apoptosis-inducing factor (AIF) in mitochondria in cells, resulting in a significant decrease in the number of apoptotic cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1135688-47-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125305.
Z-AEVD-FMK
Z-AEVD-FMK is a cell-permeant and irreversible caspase-10 inhibitor. It is a cleavable ADC linker for the synthesis of antibody active molecule conjugates (ADCs). Synonyms: Z-Ala-Glu(OMe)-Val-Asp(OMe)-fluoromethyl ketone; (5S,8S,11S,14S)-Methyl 14-(2-Fluoroacetyl)-11-isopropyl-8-(3-methoxy-3-oxopropyl)-5-methyl-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,1 3-tetraazahexadecan-16-oate; Z-A-E(OMe)-V-Asp(OMe)-FMK; Z-Ala-Glu(OMe)-Val-Asp(OMe)-FMK. Grade: ≥95%. CAS No. 1135688-47-9. Molecular formula: C28H39FN4O10. Mole weight: 610.63.
Zafirlukast
Zafirlukast (ICI 204219) is a potent orally active leukotriene D4 (LTD4) receptor antagonist. Zafirlukast shows anti-asthmatic, anti-inflammatory and anti-bacterial effects. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ICI 204219. CAS No. 107753-78-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-17492.
Zafirlukast-[13C,d3]
One of the isotopic lebelled form of Zafirlucast, which has been found to be a cysteinyl leukotriene type 1 receptor antagonist and could be as an antiasthmatic agent. Synonyms: cyclopentyl (3-(2-methoxy-4-((o-tolylsulfonyl)carbamoyl)benzyl)-1-methyl-1H-indol-5-yl)carbamate-13CD3. Grade: >99%. Molecular formula: C30[13C]H30D3N3O6S. Mole weight: 579.70.
Zafirlukast-[d7]
One of the isotopic lebelled form of Zafirlucast, which has been found to be a cysteinyl leukotriene type 1 receptor antagonist and could be as an antiasthmatic agent. Synonyms: [3-[[2-Methoxy-4-[[[(2-methylphenyl-d7)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]carbamic Acid Cyclopentyl Ester. Grade: >98%. CAS No. 1217174-18-9. Molecular formula: C31H26D7N3O6S. Mole weight: 582.73.
Zafirlukast Impurity 1
Zafirlukast Impurity 1. Uses: For analytical and research use. CAS No. 1159195-67-1. Molecular formula: C27H27N3O6S. Mole weight: 521.59. Catalog: APB1159195671.
Zafirlukast Impurity 10
Zafirlukast Impurity 10. Uses: For analytical and research use. Molecular formula: C39H42N4O7. Mole weight: 678.79. Catalog: APB12354.
Zafirlukast Impurity 11
Zafirlukast Impurity 11. Uses: For analytical and research use. Molecular formula: C40H44N4O7. Mole weight: 692.81. Catalog: APB12357.
Zafirlukast Impurity 12
Zafirlukast Impurity 12. Uses: For analytical and research use. CAS No. 1160235-24-4. Molecular formula: C46H49N5O8S. Mole weight: 831.99. Catalog: APB1160235244.
Zafirlukast Impurity 13
Zafirlukast Impurity 13. Uses: For analytical and research use. Molecular formula: C35H38N2O8. Mole weight: 614.7. Catalog: APB12359.
Zafirlukast Impurity 14
Zafirlukast Impurity 14. Uses: For analytical and research use. Molecular formula: C33H34N2O8. Mole weight: 586.64. Catalog: APB12358.
Zafirlukast Impurity 15
Zafirlukast Impurity 15. Uses: For analytical and research use. CAS No. 107754-15-4. Molecular formula: C19H18N2O5. Mole weight: 354.36. Catalog: APB107754154.
Zafirlukast Impurity 16
Zafirlukast Impurity 16. Uses: For analytical and research use. Molecular formula: C31H32ClN3O6S. Mole weight: 610.12. Catalog: APB12360.
Zafirlukast Impurity 17
Zafirlukast Impurity 17. Uses: For analytical and research use. CAS No. 1160235-28-8. Molecular formula: C49H49N5O8S. Mole weight: 868.02. Catalog: APB1160235288.
Zafirlukast Impurity 18
Zafirlukast Impurity 18. Uses: For analytical and research use. CAS No. 1391990-94-5. Molecular formula: C37H48N4O5. Mole weight: 628.81. Catalog: APB1391990945.
Zafirlukast Impurity 19
Zafirlukast Impurity 19. Uses: For analytical and research use. Molecular formula: C30H37N3O4. Mole weight: 503.64. Catalog: APB12361.
Zafirlukast Impurity 1-d3
Zafirlukast Impurity 1-d3. Uses: For analytical and research use. CAS No. 1795011-90-3. Molecular formula: C27H24D3N3O6S. Mole weight: 524.61. Catalog: APB1795011903.
Zafirlukast Impurity 2
Zafirlukast Impurity 2. Uses: For analytical and research use. CAS No. 1159195-69-3. Molecular formula: C31H33N3O6S. Mole weight: 575.68. Catalog: APB1159195693.
Zafirlukast Impurity 20
Zafirlukast Impurity 20. Uses: For analytical and research use. CAS No. 1160235-26-6. Molecular formula: C47H48N4O10S2. Mole weight: 893.04. Catalog: APB1160235266.
Zafirlukast Impurity 2-d7
Zafirlukast Impurity 2-d7. Uses: For analytical and research use. CAS No. 1794760-52-3. Molecular formula: C31H26D7N3O6S. Mole weight: 582.72. Catalog: APB1794760523.
Zafirlukast Impurity 3
Zafirlukast Impurity 3. Uses: For analytical and research use. CAS No. 107754-14-3. Molecular formula: C19H20N2O3. Mole weight: 324.4. Catalog: APB107754143.
Zafirlukast Impurity 3
Zafirlukast Impurity 3. Uses: For analytical and research use. CAS No. 1159195-70-6. Molecular formula: C31H33N3O6S. Mole weight: 575.68. Catalog: APB1159195706.
Zafirlukast Impurity 3-d7
Zafirlukast Impurity 3-d7. Uses: For analytical and research use. CAS No. 1794886-13-7. Molecular formula: C31H26D7N3O6S. Mole weight: 582.72. Catalog: APB1794886137.
Zafirlukast Impurity 4
Zafirlukast Impurity 4. Uses: For analytical and research use. CAS No. 107754-19-8. Molecular formula: C25H28N2O5. Mole weight: 436.5. Catalog: APB107754198.
Zafirlukast Impurity 4
Zafirlukast Impurity 4. Uses: For analytical and research use. CAS No. 219583-10-5. Molecular formula: C25H25N3O4S. Mole weight: 463.55. Catalog: APB219583105.
Zafirlukast Impurity 5
Zafirlukast Impurity 5. Uses: For analytical and research use. CAS No. 219582-82-8. Molecular formula: C31H33N3O7S. Mole weight: 591.68. Catalog: APB219582828.
Zafirlukast Impurity 5
Zafirlukast Impurity 5. Uses: For analytical and research use. CAS No. 107754-20-1. Molecular formula: C24H26N2O5. Mole weight: 422.5. Catalog: APB107754201.
Zafirlukast Impurity 6
Zafirlukast Impurity 6. Uses: For analytical and research use. CAS No. 219582-85-1. Molecular formula: C31H33N3O7S. Mole weight: 591.68. Catalog: APB219582851.
Zafirlukast Impurity 7
Zafirlukast Impurity 7. Uses: For analytical and research use. Molecular formula: C28H32N4O3. Mole weight: 472.59. Catalog: APB12353.
Zafirlukast Impurity 8
Zafirlukast Impurity 8. Uses: For analytical and research use. Molecular formula: C29H38N2O6. Mole weight: 510.63. Catalog: APB12355.
Zafirlukast Impurity 9
Zafirlukast Impurity 9. Uses: For analytical and research use. Molecular formula: C39H42N4O7. Mole weight: 678.79. Catalog: APB12356.
Zafirlukast m-Tolyl Isomer-[d7]
Zafirlukast m-Tolyl Isomer-[d7] is the labelled analogue of Zafirlukast m-Tolyl Isomer, which is a positional isomer and impurity of the cysteinyl leukotriene type 1 receptor antagonist, Zafirlukast. Synonyms: Zafirlukast m-Tolyl Isomer-d7; N-[3-[[2-Methoxy-4-[[[(3-methylphenyl-d7)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]carbamic Acid Cyclopentyl Ester; Zafirlukast Related Compound D-d7; Cyclopentyl 3-[2-Methoxy-4-[m-(tolyl-d7)sulfonylcarbamoyl)benzyl]-1-methylindol-5-ylcarbamate. Grade: ≥98%. CAS No. 1794760-52-3. Molecular formula: C31H26D7N3O6S. Mole weight: 582.72.
Zagociguat
Zagociguat (CY-6463) is an orally active and BBB-permeable soluble guanylate cyclase (sGC) stimulator. Zagociguat can increase cGMP levels, regulate blood pressure, improve neuronal function, reduce inflammatory responses, and exert neuroprotective and cognitive-improving effects. Zagociguat can be used in the research of neurodegenerative diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CY-6463; IW-6463. CAS No. 2201048-82-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145607.
Zagotenemab
Zagotenemab (LY3303560) is a humanized anti-tau antibody that selectively binds and neutralises tau deposits in the brain. Zagotenemab can be used in Alzheimer's disease research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY3303560. CAS No. 2019133-28-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99164.
ZAK-IN-1
ZAK-IN-1 is an orally active and selective selective leucine-zipper and sterile - α motif kinase (ZAK) inhibitor with IC50 of 4 nM and KD of 8 nM. ZAK-IN-1 exhibits excellent selectivity against a panel of 403 wild-type kinases. ZAK-IN-1 blocks p38/GATA-4 and JNK/c-Jun signaling and shows promising anti antihypertrophic cardiomyopathy (HCM) efficacy. ZAK-IN-1 can be used for the study of HCM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2362525-64-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-128326.
Z-Ala-Ala-Asn-AMC
Z-Ala-Ala-Asn-AMC is a standard substrate for legumain (EC 3.4.22.34) originally used for plant enzymes, and later found in mammalian form. Legumain may be a physiologic local regulator of human osteoclast (OCL) activity and may negatively regulate OCL. Synonyms: Z-AAN-AMC; L-Aspartamide, N-[(phenylmethoxy)carbonyl]-L-alanyl-L-alanyl-N1-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-; Benzyloxycarbonyl-Ala-Ala-Asn-4-methyl-7-coumarylamide; Benzyloxycarbonylalanyl-alanyl-asparaginyl-4-methyl-7-coumarylamide. Grade: 95%. CAS No. 149697-16-5. Molecular formula: C28H31N5O8. Mole weight: 565.57.
Z-Ala-Ala-Asn-AMC
Z-Ala-Ala-Asn-AMC (Cbz-Ala-Ala-Asn-AMC) is the legumain substrate. Overexpressed legumain in 293 HEK-Leg cells potently cleaved CBZ-Ala-Ala-Asn-AMC[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cbz-Ala-Ala-Asn-AMC. CAS No. 149697-16-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-136626.
Z-Ala-Ala-Asp-CMK
Z-Ala-Ala-Asp-CMK (Z-AAD-CMK) is a selective granzyme B inhibitor. By binding to the active site of granzyme B, Z-Ala-Ala-Asp-CMK blocks its proteolytic function. Z-Ala-Ala-Asp-CMK has anti-inflammatory activity and can be used in the research of inflammatory diseases and cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Z-AAD-CMK. CAS No. 183284-21-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10004.
Z-Ala-Ala-OH
Z-Ala-Ala-OH. Group: Biochemicals. Alternative Names: Z-L-alanyl-L-alanine. Grades: Highly Purified. CAS No. 16012-70-7. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
Z-Ala-Ala-OH
Z-Ala-Ala-OH is a useful research chemical, an intermediate for the preparation of pseudopeptide macrobicyclic cages used as receptors for N-protected dipeptide guest molecules. Synonyms: Z-L-alanyl-L-alanine; N-Cbz-L-Alanyl-L-Alanine; L-Alanine, N-[(Phenylmethoxy)Carbonyl]-L-Alanyl-; Benzyloxycarbonylalanyl Alanine; (S)-2-((S)-2-(((Benzyloxy)Carbonyl)Amino)Propanamido)Propanoic Acid; Z Ala Ala OH. Grade: ≥ 99% (HPLC). CAS No. 16012-70-7. Molecular formula: C14H18N2O5. Mole weight: 294.31.
Z-Ala-Ala-OH 99+% (HPLC)
Z-Ala-Ala-OH 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 16012-70-7. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences.
Worldwide
Z-Ala-Gly-OH
Z-Ala-Gly-OH. Synonyms: Z-L-alanyl-L-glycine; N-Carbobenzoxy-L-Alanylgylcine; Z Ala Gly OH. Grade: ≥ 96% (HPLC). CAS No. 3235-17-4. Molecular formula: C13H16N2O5. Mole weight: 280.28.
Z-Ala-Gly-OH
Z-Ala-Gly-OH. Group: Biochemicals. Alternative Names: Z-L-alanyl-L-glycine. Grades: Highly Purified. CAS No. 3235-17-4. Pack Sizes: 5g. US Biological Life Sciences.