A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Z-Ala-Ala-OH. Group: Biochemicals. Alternative Names: Z-L-alanyl-L-alanine. Grades: Highly Purified. CAS No. 16012-70-7. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
Z-Ala-Ala-OH 99+% (HPLC)
Z-Ala-Ala-OH 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 16012-70-7. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences.
Worldwide
Z-Ala-Gly-OH
Z-Ala-Gly-OH. Group: Biochemicals. Alternative Names: Z-L-alanyl-L-glycine. Grades: Highly Purified. CAS No. 3235-17-4. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
Z-Ala-Gly-OH
Z-Ala-Gly-OH. Alternative Names: Z-L-alanyl-L-glycine; N-Carbobenzoxy-L-Alanylgylcine; Z Ala Gly OH. Grades: ≥ 96% (HPLC). CAS No. 3235-17-4. Molecular formula: C13H16N2O5. Mole weight: 280.28.
Z-Ala-His-OMe
Z-Ala-His-OMe is a useful research intermediate for the synthesis of other histidine-containing peptides. Alternative Names: (S)-methyl 2-((S)-2-(benzyloxycarbonylamino)propanamido)-3-(1H-imidazol-4-yl)propanoate; Z Ala His OMe. Grades: ≥ 99% (TLC). CAS No. 32303-82-5. Molecular formula: C18H22N4O5. Mole weight: 374.40.
Z-Ala-His-OMe
Z-Ala-His-OMe. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 2.5g. US Biological Life Sciences.
Worldwide
Z-ALA-LEU-OH
Z-ALA-LEU-OH. Alternative Names: n-benzyloxycarbonyl-l-alanyl-l-leucine; (S)-2-((S)-2-(((Benzyloxy)carbonyl)amino)propanamido)-4-methylpentanoic acid. CAS No. 24959-68-0. Molecular formula: C17H24N2O5. Mole weight: 336.38.
Z-Ala-Lys-OH
Z-Ala-Lys-OH. Alternative Names: N-cbz-l-alanyl-l-lysine; (S)-6-amino-2-((S)-2-(benzyloxycarbonylamino)propanamido)hexanoic acid; Z Ala Lys OH. Grades: 99%. CAS No. 76264-07-8. Molecular formula: C17H25N3O5. Mole weight: 351.40.
Z-Ala-Lys-OH
Z-Ala-Lys-OH. Group: Biochemicals. Grades: Highly Purified. CAS No. 76264-07-8. Pack Sizes: 100mg, 250mg, 500mg. US Biological Life Sciences.
Worldwide
Z-Ala-Lys-OH 99+%
Z-Ala-Lys-OH 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 500mg. US Biological Life Sciences.
Worldwide
Z-Ala-Met-OH
Z-Ala-Met-OH. Alternative Names: Z-L-alanyl-L-methionine; N-cbz-l-alanyl-l-methionine; (2S)-2-[((2S)-2-{[(benzyloxy)carbonyl]amino}propanoyl)amino]-4-(methylthio)butanoic acid; Z Ala Met OH. Grades: ≥ 98% (TLC). CAS No. 76264-05-6. Molecular formula: C16H22N2O5S. Mole weight: 354.43.
Z-Ala-Met-OH
Z-Ala-Met-OH. Group: Biochemicals. Alternative Names: Z-L-alanyl-L-methionine. Grades: Highly Purified. CAS No. 76264-05-6. Pack Sizes: 1g, 2g. US Biological Life Sciences.
Worldwide
Z-Ala-Met-OH 99+%
Z-Ala-Met-OH 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 2.5g. US Biological Life Sciences.
Worldwide
Z-Ala-Phe-OH
Substrate for carboxypeptidase Y. Alternative Names: Z-L-alanyl-L-phenylalanine; N-Carbobenzoxy-L-alanyl-L-phenylalanine; (S)-2-((S)-2-(benzyloxycarbonylamino)propanamido)-3-phenylpropanoic acid; Z Ala Phe OH. Grades: ≥ 98% (HPLC). CAS No. 2768-53-8. Molecular formula: C20H22N2O5. Mole weight: 370.41.
Z-Ala-Phe-OH
Z-Ala-Phe-OH. Group: Biochemicals. Alternative Names: Z-L-alanyl-L-phenylalanine; N-Carbobenzoxy-L-alanyl-L-phenylalanine. Grades: Highly Purified. CAS No. 2768-53-8. Pack Sizes: 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
Z-Ala-Phe-OH 98+% (HPLC)
Z-Ala-Phe-OH 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 2768-53-8. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
Z-Ala-Pro-OH
Z-Ala-Pro-OH. Alternative Names: 1-[2-(phenylmethoxycarbonylamino)propanoyl]pyrrolidine-2-carboxylic acid. CAS No. 21027-01-0. Molecular formula: C16H20N2O5. Mole weight: 320.34.
Z-Ala-Pro-Phe-chloromethylketone
Z-Ala-Pro-Phe-chloromethylketone is an inhibitor of the Ca2+- regulated nuclear scaffold proteinase (CRNSP). Alternative Names: Z-APF-CMK; N-benzyloxycarbonyl-Ala-Pro-Phe-chloromethyl ketone. Grades: >98%. CAS No. 217658-18-9. Molecular formula: C26H30ClN3O5. Mole weight: 499.99.
Z-ALA-PRO-PNA
Z-ALA-PRO-PNA. Alternative Names: benzyl (S)-1-((S)-2-(4-nitrophenylcarbamoyl)pyrrolidin-1-yl)-1-oxopropan-2-ylcarbamate. Grades: >99%. CAS No. 66382-56-7. Molecular formula: C22H24N4O6. Mole weight: 440.45.
Zalcitabine
Zalcitabine is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI). Uses: Anti-hiv agents. Alternative Names: ddC; 2',3'-Dideoxycytidine; Dideoxycytidine; Hivid; NSC 606170; D2C; 4-Amino-1-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one. Grades: ≥95%. CAS No. 7481-89-2. Molecular formula: C9H13N3O3. Mole weight: 211.22.
Zalcitabine
Zalcitabine is a potent nucleoside analogue reverse transcriptase inhibitor used in the treatment of HIV infection. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2',3'-Dideoxycytidine; ddC; Dideoxycytidine. CAS No. 7481-89-2. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-17392.
Zalcitabine Impurity 1
Zalcitabine Impurity 1. Uses: For analytical and research use. CAS No. 1179343-05-5. Molecular formula: C9H17N4O6P. Mole weight: 308.23. Catalog: APB1179343055.
Zalcitabine Monophosphate Ammonium Salt
Zalcitabine Monophosphate Ammonium Salt can be used as an intermediate in the synthesis of Zalcitabine Triphosphate, which is an inhibitor of viral RNA synthesis. Alternative Names: 2',3'-Dideoxycytidine 5'-monophosphate Ammonium Salt;2',3'-Dideoxycytidine monophosphate Ammonium Salt. CAS No. 1179343-05-5. Molecular formula: C9H18N4O6P. Mole weight: 309.24.
Zalcitabine Monophosphate Sodium Salt
Zalcitabine monophosphate Sodium Salt is a metabolite of Zalcitabine, and serves as an inhibitor of viral RNA synthesis. Alternative Names: 2',3'-Dideoxycytidine 5'-monophosphate Sodium Salt; 2',3'-Dideoxycytidine monophosphate Sodium Salt. Grades: 95%. CAS No. 104086-76-2. Molecular formula: C9H13N3NaO6P. Mole weight: 313.18.
Zalcitabine Related Compound A
Zalcitabine Related Compound A. Uses: For analytical and research use. CAS No. 7481-88-1. Mole weight: 209.20. Catalog: AP7481881.
Zalcitabine Triphosphate Trisodium Salt
Zalcitabine Triphosphate Trisodium Salt has the free acid form of Zalcitabine Triphosphate. And it can serve as an inhibitor of viral RNA synthesis. As well as a metabolite of Zalcitabine. Alternative Names: 2',3'-Dideoxycytidine-5'-triphosphate Trisodium Salt. Grades: 95%. Molecular formula: C9H13N3Na3O12P3. Mole weight: 517.1.
Zalcitabine Triphosphate Trisodium Salt
Zalcitabine Triphosphate Trisodium Salt. Group: Biochemicals. Alternative Names: 2',3'-Dideoxycytidine-5'-triphosphate Trisodium Salt. Grades: Highly Purified. Pack Sizes: 1 mg. Molecular Formula: C9H13N3Na3O12P3, Molecular Weight: 517.1. US Biological Life Sciences.
Worldwide
Zaldaride maleate
Zaldaride maleate (CGS-9343B) is a potent, orally active and selective inhibitor of calmodulin. Zaldaride maleate inhibits CaM (calmodulin)-stimulated cAMP phosphodiesterase activity, with an IC50 of 3.3 nM[1][2]. Zaldaride maleate prevents estrogen-induced transcription activation by ER, reversibly blocks voltage-activated Na+, Ca2+ and K+ currents in PC12 cells and inhibits nAChR[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CGS-9343B; KW 5617. CAS No. 109826-27-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-105118A.
Zaleplon Formamide
Zaleplon Formide is an impurity of Zaleplon (Z145000), a selective non-benzodiazepine GABAA receptor agonist. Group: Biochemicals. Alternative Names: N-[3-(3-Cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-N-ethyl-formamide; Zaleplon Impurity. Grades: Highly Purified. CAS No. 1227694-78-1. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Zaleplon Impurity 3
Zaleplon Impurity 3. Uses: For analytical and research use. CAS No. 1227694-78-1. Molecular formula: C16H13N5O. Mole weight: 291.31. Catalog: APB1227694781.
Zaleplon Impurity 4
Zaleplon Impurity 4. Uses: For analytical and research use. CAS No. 159225-99-7. Molecular formula: C17H15N5O2. Mole weight: 321.34. Catalog: APB159225997.
Zaleplon Related Compound A
Zaleplon Related Compound A. Uses: For analytical and research use. CAS No. 1227694-96-3. Mole weight: 260.33. Catalog: AP1227694963.
Zaleplon Related Compound C
Zaleplon Related Compound C. Uses: For analytical and research use. CAS No. 940951-54-2. Mole weight: 323.35. Catalog: AP940951542.
Z-Allo-Thr-OMe
Z-Allo-Thr-OMe. CAS No. 98777-34-5. Molecular formula: C13H17NO5. Mole weight: 267.3.
Z-α-aminoisobutyric acid
Z-α-aminoisobutyric acid. Alternative Names: Z-Aib-OH; Z-α-methylalanine. Grades: ≥ 99% (HPLC). CAS No. 15030-72-5. Molecular formula: C12H15NO4. Mole weight: 237.30.
Z-alpha-aminoisobutyric acid
Z-alpha-aminoisobutyric acid. Group: Biochemicals. Alternative Names: Z-Aib-OH; Z-a-methylalanine. Grades: Highly Purified. CAS No. 15030-72-5. Pack Sizes: 2g, 5g, 10g, 25g, 50g. US Biological Life Sciences.
Worldwide
Zaltenibart
Zaltenibart (OMS906) is an IgG4 humanized monoclonal antibody and MASP-3 inhibitor. By inhibiting MASP-3, Zaltenibart achieves upstream inhibition of the alternative complement pathway. MASP-3 is an upstream activator of Factor D (Factor D), a key enzyme in the alternative complement pathway. Zaltenibart prevents both intravascular hemolysis and extravascular hemolysis. Zaltenibart is applicable to research related to paroxysmal nocturnal hemoglobinuria[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OMS906. CAS No. 2527079-60-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990952.
Zaltoprofen
Anti-inflammatory activity resides in (S)-enantiomer. Group: Biochemicals. Alternative Names: 10,11-Dihydro-α-methyl-10-oxodibenzo[b,f]thiepin-2-acetic Acid; 2-(10,11-Dihydro-10-oxodibenzo[b,f]thiepin-2-yl)propionic Acid; CN-100; Soreton; Peon. Grades: Highly Purified. CAS No. 74711-43-6. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Zaltoprofen Impurity 1
Zaltoprofen Impurity 1. Uses: For analytical and research use. Molecular formula: C17H16O3S. Mole weight: 300.37. Catalog: APB12350.
Zaltoprofen Impurity 2
Zaltoprofen Impurity 2. Uses: For analytical and research use. Molecular formula: C17H14O3S. Mole weight: 298.36. Catalog: APB12348.
Zaltoprofen Impurity 3
Zaltoprofen Impurity 3. Uses: For analytical and research use. CAS No. 134085-79-3. Molecular formula: C17H14O4S. Mole weight: 314.36. Catalog: APB134085793.
Zaltoprofen Impurity 4
Zaltoprofen Impurity 4. Uses: For analytical and research use. Molecular formula: C23H22O9S. Mole weight: 474.48. Catalog: APB12351.
Zalunfiban dihydrochloride
Zalunfiban (RUC-4) dihydrochloride is a potent, selective platelet αIIbβ3 antagonist (IC50=45 nM). Zalunfiban dihydrochloride can be used for the research of myocardial infarction (MI)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RUC-4 dihydrochloride. CAS No. 2815778-41-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119350B.
Zalutumumab
Zalutumumab is a high affinity, completely human IgG1 monoclonal antibody targeting EGFR. Zalutumumab binds to domain III of the EGF receptor and acts by blocking the binding of EGF and by sterically interfering with the active conformation of the receptor. Zalutumumab binds with IgG and its Fab fragment with EC50s of 7 and 19 nM, respectively. Zalutumumab can be used for the research of cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2F8; HUMAX-EGFR. CAS No. 667901-13-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99155.
Zamaporvint
Zamaporvint (RXC004) is an orally active and selective inhibitor of Wnt. Zamaporvint targete membrane-bound o-acyltransferase Porcupine and inhibited Wnt ligand palmitoylation, secretion, and pathway activation. Zamaporvint displays a favorable pharmacokinetic profile and shows potent antiproliferative effects in Wnt ligand-dependent colorectal and pancreatic cell lines. Zamaporvint possesses multiple antitumor mechanisms and can be used in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RXC004. CAS No. 1900754-56-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153855.
Zampilimab
Zampilimab (UCB-7858) is a monoclonal antibody against transglutaminase 2 (TG2). Zampilimab inhibits TG2 crosslinking transamidation activity with an IC50 of 0.25 nM and a Kd of <50 pM. Zampilimab improves renal fibrosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: UCB-7858. CAS No. 2098280-42-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P99512.
Zanamivir
Zanamivir is an influenza viral neuraminidase inhibitor with IC50 values of 0.95 nM and 2.7 nM for influenza A and B, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 139110-80-8. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13210.
Zanamivir-[13C,15N2]
Zanamivir-[13C,15N2] is the labelled analogue of Zanamivir, which is an acetylneuraminic derivative and has been found to be an influenza viral neuraminidase inhibitor. Alternative Names: Zanamivir-13C,15N2; 5-Acetylamino-4-[(aminoiminomethyl)amino]-2,6-anhydro-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic Acid-13C,15N2. Grades: 95% by HPLC; 98% atom 13C; 98% atom 15N. CAS No. 1276528-62-1. Molecular formula: C11[13C]H20N2[15N]2O7. Mole weight: 335.29.
Zanamivir Amine
A synthetic precursor of Zanamivir. Group: Biochemicals. Alternative Names: 5-(Acetylamino)-4-amino-2,6-anhydro-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic Acid. Grades: Highly Purified. CAS No. 130525-62-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Zanamivir Amine
Zanamivir Amine is used as a precursor in the synthesis of Zanamivir. Alternative Names: 4-α-Amino-N-acetyl-2-deoxy-2,3-didehydro-D-neuraminate; Zanamivir intermediates A. Grades: 95%. CAS No. 130525-62-1. Molecular formula: C11H18N2O7. Mole weight: 290.272.
Zanamivir Amine Triacetate Methyl Ester
A synthetic precursor of Zanamivir, an antiviral agent against influenza virus. Alternative Names: methyl (2R,3R,4S)-3-acetamido-4-amino-2-[(1S,2R)-1,2,3-triacetyloxypropyl]-3,4-dihydro-2H-pyran-6-carboxylate. CAS No. 139110-70-6. Molecular formula: C18H26N2O10. Mole weight: 430.41.
Zanamivir Amine Triacetate Methyl Ester
A synthetic precursor of Zanamivir , as antiviral agents against influenza virus. Group: Biochemicals. Alternative Names: 5-(Acetylamino)-4-amino-2,6-anhydro-3,4,5-trideoxy-. Grades: Highly Purified. CAS No. 139110-70-6. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Zanamivir Azide Methyl Ester
An intermediate used in the preparation of Zanamivir derivatives. Group: Biochemicals. Alternative Names: 5-(Acetylamino)-2,6-anhydro-4-azido-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic Acid Methyl Ester. Grades: Highly Purified. CAS No. 152178-79-5. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Zanamivir Azide Triacetate Methyl Ester
An intermediate used in the preparation of Zanamivir derivatives. Alternative Names: (1S,2R)-1-((2R,3R,4S)-3-acetamido-4-azido-6-(methoxycarbonyl)-3,4-dihydro-2H-pyran-2-yl)propane-1,2,3-triyl triacetate; 5-(acetylamino)-2,6-anhydro-4-azido-3,4,5-trideoxy-, methyl ester, 7,8,9-triacetate; Methyl 5-acetamido-7,8,9-O-triacetyl-2,6-anhydro-4-azido-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonate. Grades: 95%. CAS No. 130525-58-5. Molecular formula: C18H24N4O10. Mole weight: 456.41.
Zanamivir Azide Triacetate Methyl Ester
An intermediate used in the preparation of Zanamivir derivatives. Group: Biochemicals. Alternative Names: 5-(Acetylamino)-2,6-anhydro-4-azido-3,4,5-trideoxy-D-glycero-D-galacto-non-2-enonic Acid Methyl Ester 7,8,9-Triacetate. Grades: Highly Purified. CAS No. 130525-58-5. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Zanamivir EP Impurity A
Zanamivir EP Impurity A. Uses: For analytical and research use. Molecular formula: C24H36N6O15. Mole weight: 648.58. Catalog: APB12332.
Zanamivir EP Impurity C
Zanamivir EP Impurity C. Uses: For analytical and research use. CAS No. 130525-62-1. Molecular formula: C11H18N2O7. Mole weight: 290.27. Catalog: APB130525621.
Zanamivir EP Impurity D
Zanamivir EP Impurity D. Uses: For analytical and research use. CAS No. 179531-53-4. Molecular formula: C12H19N3O8. Mole weight: 333.3. Catalog: APB179531534.
Zanamivir EP Impurity E
Zanamivir EP Impurity E. Uses: For analytical and research use. Molecular formula: C13H22N6O7. Mole weight: 374.35. Catalog: APB12333.
Zanamivir EP Impurity F
Zanamivir EP Impurity F. Uses: For analytical and research use. CAS No. 4023-00-1. Molecular formula: C4H6N4. Mole weight: 110.1. Catalog: APB4023001.
Zanamivir EP Impurity F
Zanamivir EP Impurity F. Uses: For analytical and research use. CAS No. 4023-2-3. Molecular formula: C4H7ClN4. Mole weight: 146.58. Catalog: APB4023023.
Zanamivir EP Impurity H
Zanamivir EP Impurity H. Uses: For analytical and research use. Molecular formula: C12H20N4O7. Mole weight: 332.31. Catalog: APB12334.
Zanamivir (hydrate)
Zanamivir is a neuraminidase inhibitor used in the treatment and prophylaxis of influenza caused by influenza A virus and influenza B virus. Alternative Names: Relenza; GG 167; 2,3-Didehydro-2,4-dideoxy-4-guanidine-N-acetyl-acetyl-D-neuraminic acid; 4-Guanidino-2,4-dideoxy-2,3-didehydro-N-acetylneuraminic acid; 5-Acetamino-2,6-anhydro-4-guanidino-3,4,5-trideoxy-D-galcto-non-enoic acid. Grades: >98%. CAS No. 139110-80-8. Molecular formula: C12H22N4O8. Mole weight: 350.33.
Zanamivir Impurity 10
Zanamivir Impurity 10. Uses: For analytical and research use. CAS No. 130525-58-5. Molecular formula: C18H24N4O10. Mole weight: 456.41. Catalog: APB130525585.
Zanamivir Impurity 11
Zanamivir Impurity 11. Uses: For analytical and research use. CAS No. 1228216-82-7. Molecular formula: C19H25N3O10. Mole weight: 455.42. Catalog: APB1228216827.
Zanamivir Impurity 12
Zanamivir Impurity 12. Uses: For analytical and research use. CAS No. 139110-70-6. Molecular formula: C18H26N2O10. Mole weight: 430.41. Catalog: APB139110706.
Zanamivir Impurity 13
Zanamivir Impurity 13. Uses: For analytical and research use. CAS No. 1627557-27-0. Molecular formula: C14H24N4O7. Mole weight: 360.37. Catalog: APB1627557270.
Zanamivir Impurity 14
Zanamivir Impurity 14. Uses: For analytical and research use. CAS No. 166830-74-6. Molecular formula: C16H26N2O9. Mole weight: 390.39. Catalog: APB166830746.
Zanamivir Impurity 9
Zanamivir Impurity 9. Uses: For analytical and research use. CAS No. 152178-79-5. Molecular formula: C12H18N4O7. Mole weight: 330.3. Catalog: APB152178795.
Zandatrigine
Zandatrigine (NBI-921352; XEN901) is a selective, orally active, voltage-gated sodium channel NaV1.6/SCN8A inhibitor that can penetrate the blood-brain barrier. Zandatrigine inhibits sodium influx by non-covalently binding to the VSD4 structure of NaV1.6, blocking the persistent and resuscitative currents under pathological conditions. Zandatrigine can reduce neuronal hyperexcitability and reduce epileptic seizures. Zandatrigine is 134-756-fold selective for other isoforms such as NaV1.1 and NaV1.2, and has minimal effect on NaV1.1 expressed by inhibitory interneurons. Zandatrigine can be used to study NaV1.6-mediated neuroexcitability diseases such as SCN8A-related developmental epileptic encephalopathy (SCN8A-DEE) and adult focal epilepsy[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NBI-921352; XEN901. CAS No. 2154406-04-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147423.