A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Zanamivir Impurity 12. Uses: For analytical and research use. CAS No. 139110-70-6. Molecular formula: C18H26N2O10. Mole weight: 430.41. Catalog: APB139110706.
Zanamivir Impurity 13
Zanamivir Impurity 13. Uses: For analytical and research use. CAS No. 1627557-27-0. Molecular formula: C14H24N4O7. Mole weight: 360.37. Catalog: APB1627557270.
Zanamivir Impurity 14
Zanamivir Impurity 14. Uses: For analytical and research use. CAS No. 166830-74-6. Molecular formula: C16H26N2O9. Mole weight: 390.39. Catalog: APB166830746.
Zanamivir Impurity 9
Zanamivir Impurity 9. Uses: For analytical and research use. CAS No. 152178-79-5. Molecular formula: C12H18N4O7. Mole weight: 330.3. Catalog: APB152178795.
Zandatrigine
Zandatrigine (NBI-921352; XEN901) is a selective, orally active, voltage-gated sodium channel NaV1.6/SCN8A inhibitor that can penetrate the blood-brain barrier. Zandatrigine inhibits sodium influx by non-covalently binding to the VSD4 structure of NaV1.6, blocking the persistent and resuscitative currents under pathological conditions. Zandatrigine can reduce neuronal hyperexcitability and reduce epileptic seizures. Zandatrigine is 134-756-fold selective for other isoforms such as NaV1.1 and NaV1.2, and has minimal effect on NaV1.1 expressed by inhibitory interneurons. Zandatrigine can be used to study NaV1.6-mediated neuroexcitability diseases such as SCN8A-related developmental epileptic encephalopathy (SCN8A-DEE) and adult focal epilepsy[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NBI-921352; XEN901. CAS No. 2154406-04-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147423.
Zandelisib
Zandelisib (ME-401) is a selective, orally active, non-covalent inhibitor of PI3Kδ. Zandelisib can sustainably inhibit AKT phosphorylation and downstream signaling pathways. Zandelisib can be used in the study of malignancies such as relapsed/refractory B-cell lymphoma[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ME-401; PWT-143. CAS No. 1401436-95-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109198.
Zanidatamab
Zanidatamab (ZW25) is a humanised, bispecific monoclonal antibody targeting 2 distinct HER2 epitopes (ECD2 and ECD4). Zanidatamab has anti-tumour activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZW 25; ZW-49 Antibody. CAS No. 2169946-15-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P99380.
Zanolimumab
Zanolimumab (Anti-Human CD4 Recombinant Antibody) is a fully human monoclonal antibody targets CD4. Zanolimumab effectively inhibits T-cell receptor (TCR) signal transduction. Zanolimumab can be used for the research of heumatoid arthritis, psoriasis, melanoma, cutaneous and peripheral T-cell lymphoma[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Anti-Human CD4 Recombinant Antibody. CAS No. 652153-01-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99266.
Zansecimab
Zansecimab (LY-3127804) is a monoclonal antibody against angiopoietin 2 (Ang - 2). Zansecimab can be used in research on angiogenesis, immunomodulation and anti-tumor activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY-3127804. CAS No. 2415205-37-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99510.
Zanubrutinib
Zanubrutinib (BGB-3111) is a selective and orally active Bruton tyrosine kinase (Btk) inhibitor (IC50: 0.3 nM)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BGB-3111. CAS No. 1691249-45-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101474A.
Zanubrutinib 4-Acryloyl Impurity
Zanubrutinib 4-Acryloyl Impurity. Uses: For analytical and research use. Molecular formula: C27H29N5O3. Mole weight: 471.6. Catalog: APB000037.
Zanubrutinib Acid Impurity
Zanubrutinib Acid Impurity. Uses: For analytical and research use. Molecular formula: C24H26N4O3. Mole weight: 418.5. Catalog: APB000038.
Zanubrutinib Amino Acid Impurity
Zanubrutinib Amino Acid Impurity. Uses: For analytical and research use. Molecular formula: C27H31N5O4. Mole weight: 489.6. Catalog: APB000039.
Zanubrutinib De-BOC Acid Impurity
Zanubrutinib De-BOC Acid Impurity. Uses: For analytical and research use. Molecular formula: C23H26N4O. Mole weight: 374.5. Catalog: APB000040.
Zanubrutinib Des Amide Impurity
Zanubrutinib Des Amide Impurity. Uses: For analytical and research use. Molecular formula: C27H29N3O2. Mole weight: 427.5. Catalog: APB000041.
Zanubrutinib Di Acryloyl Impurity
Zanubrutinib Di Acryloyl Impurity. Uses: For analytical and research use. Molecular formula: C30H31N5O4. Mole weight: 525.6. Catalog: APB000042.
Zanubrutinib Impurity 1
Zanubrutinib Impurity 1. Uses: For analytical and research use. CAS No. 1691249-44-1. Molecular formula: C27H24D5N5O4. Mole weight: 476.59. Catalog: APB1691249441.
Zanubrutinib Impurity 10
Zanubrutinib Impurity 10. Uses: For analytical and research use. CAS No. 2190506-56-8. Molecular formula: C29H33N5O3. Mole weight: 499.62. Catalog: APB2190506568.
Zanubrutinib Impurity 11
Zanubrutinib Impurity 11. Uses: For analytical and research use. CAS No. 2190506-57-9. Molecular formula: C24H25N5O. Mole weight: 399.5. Catalog: APB2190506579.
Zanubrutinib Impurity 11
Zanubrutinib Impurity 11. Uses: For analytical and research use. CAS No. 1799799-87-3. Molecular formula: C15H26N2O3. Mole weight: 282.4. Catalog: APB1799799873.
Zanubrutinib Impurity 12
Zanubrutinib Impurity 12. Uses: For analytical and research use. Molecular formula: C24H25N5O. Mole weight: 399.5. Catalog: APB12344.
Zanubrutinib Impurity 13
Zanubrutinib Impurity 13. Uses: For analytical and research use. CAS No. 1633350-06-7. Molecular formula: C27H29N5O3. Mole weight: 471.56. Catalog: APB1633350067.
Zanubrutinib Impurity 14
Zanubrutinib Impurity 14. Uses: For analytical and research use. Molecular formula: C28H32N4O4. Mole weight: 488.6. Catalog: APB000043.
Zanubrutinib Impurity 15
Zanubrutinib Impurity 15. Uses: For analytical and research use. Molecular formula: C28H32N4O4. Mole weight: 488.6. Catalog: APB000044.
Zanubrutinib Impurity 16
Zanubrutinib Impurity 16. Uses: For analytical and research use. Molecular formula: C28H32N4O4. Mole weight: 488.6. Catalog: APB000045.
Zanubrutinib Impurity 2
Zanubrutinib Impurity 2. Uses: For analytical and research use. CAS No. 1633352-71-2. Molecular formula: C24H27N5O2. Mole weight: 417.51. Catalog: APB1633352712.
Zanubrutinib Impurity 2
Zanubrutinib Impurity 2. Uses: For analytical and research use. CAS No. 1633351-79-7. Molecular formula: C27H30ClN5O3. Mole weight: 508. Catalog: APB1633351797.
Zanubrutinib Impurity 3
Zanubrutinib Impurity 3. Uses: For analytical and research use. CAS No. 2215-77-2. Molecular formula: C13H10O3. Mole weight: 214.22. Catalog: APB2215772.
Zanubrutinib Impurity 3
Zanubrutinib Impurity 3. Uses: For analytical and research use. CAS No. 2432022-47-2. Molecular formula: C27H27N5O2. Mole weight: 453.5. Catalog: APB2432022472.
Zanubrutinib Impurity 4
Zanubrutinib Impurity 4. Uses: For analytical and research use. CAS No. 330792-68-2. Molecular formula: C16H10N2O2. Mole weight: 262.27. Catalog: APB330792682.
Zanubrutinib Impurity 5
Zanubrutinib Impurity 5. Uses: For analytical and research use. CAS No. 330792-69-3. Molecular formula: C17H12N2O2. Mole weight: 276.3. Catalog: APB330792693.
Zanubrutinib Impurity 6
Zanubrutinib Impurity 6. Uses: For analytical and research use. CAS No. 206989-61-9. Molecular formula: C12H21NO3. Mole weight: 227.3. Catalog: APB206989619.
Zanubrutinib Impurity 7
Zanubrutinib Impurity 7. Uses: For analytical and research use. CAS No. 960201-86-9. Molecular formula: C15H26N2O3. Mole weight: 282.38. Catalog: APB960201869.
Zanubrutinib Impurity 8
Zanubrutinib Impurity 8. Uses: For analytical and research use. CAS No. 330792-70-6. Molecular formula: C16H12N4O. Mole weight: 276.3. Catalog: APB330792706.
Zanubrutinib Impurity 9
Zanubrutinib Impurity 9. Uses: For analytical and research use. CAS No. 2190506-55-7. Molecular formula: C29H29N5O3. Mole weight: 495.58. Catalog: APB2190506557.
Zanubrutinib Nitroso Impurity 1
Zanubrutinib Nitroso Impurity 1. Uses: For analytical and research use. Molecular formula: C24H26N6O3. Mole weight: 446.5. Catalog: APB000046.
Zanubrutinib Nitroso Impurity 2
Zanubrutinib Nitroso Impurity 2. Uses: For analytical and research use. Molecular formula: C24H26N6O3. Mole weight: 446.5. Catalog: APB000047.
Zanubrutinib (Standard)
Zanubrutinib (Standard) is the analytical standard of Zanubrutinib. This product is intended for research and analytical applications. Zanubrutinib (BGB-3111) is a selective and orally active Bruton tyrosine kinase (Btk) inhibitor (IC50: 0.3 nM)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BGB-3111 (Standard). CAS No. 1691249-45-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101474AR.
Zanzalintinib
Zanzalintinib (XL092) is an orally active, ATP-competitive inhibitor of multiple receptor tyrosine kinases (RTKs) including MET, VEGFR2, AXL and MER, with IC50s in cell-based assays of 15 nM, 1.6 nM, 3.4 nM, 7.2 nM respectively. Zanzalintinib exhibits anti-tumor activity. Zanzalintinib has the potential for kinase-dependent diseases and conditions research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: XL092. CAS No. 2367004-54-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138696.
ZAP-180013
ZAP-180013 is a zeta-chain-associated protein kinase 70 (ZAP-70) inhibitor with an IC50 of 1.8 μM. ZAP-180013 inhibits the interaction of ZAP-70 SH2 domain with immunoreceptor tyrosine-based activation motif (ITAMs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 873080-25-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136179.
ZAP-70 Tyrosine Kinase human, Recombinant
ZAP-70 is protein tyrosine kinase of the Syk family that is localized exclusively to the cytosol of T cells and natural killer cells. It is required for T cell activation. It is activated by Lck-mediated phosphorylation of its tyrosine residues. ZAP-70 Tyrosine Kinase is a protein belongs to Syk family and is essential for T cell activation. It facilitates the upregulation of Fas ligand in activation-induced T cell apoptosis. Additionally, it also plays a pivotal role in LFA-1-dependent T Cell Migration. > 90% (sds-page), recombinant, expressed in baculovirus infected insect cells (histidine tagged), buffered aqueous glycerol solution, > 150 u/mg. Applications: Human zap-70 tyrosine kinase was used for mapping the phosphorylation sites on lat (linker for activation of t cells) for investigating the mechanism of activation of signalling proteins in t cells. Group: Enzymes. Synonyms: ZAP-70 Tyrosine Kinase; Zeta-chain-associated protein kinase 70; ZAP-70; SRK; STCD; STD; TZK; ZAP70. Purity: > 90% (SDS-PAGE). ZAP70. Mole weight: mol wt 70 kDa. Activity: > 150 U/mg. Stability: -70°C. Form: buffered aqueous glycerol solution. Source: baculovirus infected insect cells (Histidine tagged). Species: Human. ZAP-70 Tyrosine Kinase; Zeta-chain-associated protein kinase 70; ZAP-70; SRK; STCD; STD; TZK; ZAP70. Cat No: NATE-0738.
ZAPA sulfate
ZAPA sulfate. Group: Biochemicals. Grades: Purified. CAS No. 371962-01-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Zapnometinib
Zapnometinib (PD0184264), an active metabolite of CI-1040, is a MEK inhibitor, with an IC50 of 5.7 nM. Zapnometinib exhibits antiviral activity against influenza virus and antibacterial activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PD0184264; ATR-002. CAS No. 303175-44-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139558.
Zaprinast
Zaprinast. Group: Biochemicals. Grades: Purified. CAS No. 37762-06-4. Pack Sizes: 25mg. US Biological Life Sciences.
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Zaprinast
Zaprinast (M&B 22948) is a selective inhibitor of cGMP-selective Phosphodiesterase (PDE5). Zaprinast causes a significant increase in cGMP levels in myocytes. Zaprinast is a G protein-coupled receptor 35 (GPR35) agonist which activates rat GPR35 strongly and activates human GPR35 moderately. Zaprinast reduces vessel remodeling through antiproliferative and proapoptotic effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: M&B 22948. CAS No. 37762-06-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1816.
Cell-permeable. A selective inhibitor of cGMP-specific phosphodiesterase (PDE V) (IC50 = 0.45uM). Inhibits PDE IX only at higher concentrations (IC50 = 35uM). Group: Biochemicals. Alternative Names: 1,4-Dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo(4,5-d)pyrimidin-7-one, M&B 22948. Grades: Highly Purified. CAS No. 37762-06-4. Pack Sizes: 25mg. US Biological Life Sciences.
A selective inhibitor of cyclic-GMP phosphodiesterase (PDE V, calmodulin insensitive). Since cGMP mediates the vasorelaxant action of nitric oxide, as well as the natriuretic and diuretic effect of a. Group: Biochemicals. Alternative Names: 1,4-Dihydro-5-[2-propoxyphenyl]-7H-1,2,3-triazolo[4,5-d]pyrimidine-7-one. Grades: Highly Purified. CAS No. 37762-06-4. Pack Sizes: 100mg. US Biological Life Sciences.
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Zaptuzumab
Zaptuzumab (AD5-10) is a DR5-specific humanized monoclonal antibody that selectively binds to DR5 with high affinity. Zaptuzumab specifically induces cancer cell death by both caspase-apoptosis and autophagic cell death (ACD). Zaptuzumab activates both ADCC and CDC. Zaptuzumab induces ROS generation and GSH level reduction. Zaptuzumab shows a significant suppression of the tumor growth and good safety in various xenografts mice tumor models[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AD5-10; oba-01 Antibody. CAS No. 2378046-35-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P991570.
Zaragozic acid A
Zaragozic acid A is a fungal metabolite that acts as a reversible competitive inhibitor of squalene synthase. Zaragozic acid A is an inhibitor of acute hepatic cholesterol synthesis in mouse (IC50 = 6 μM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Squalestatin S1. CAS No. 142561-96-4. Pack Sizes: 1 mg. Product ID: HY-116290.
Zaragozic acid a trisodium salt
Zaragozic acid a trisodium salt. CAS No. 144541-82-2. Product ID: ACM144541822. Molecular formula: C35H46Na3O14. Mole weight: 756.68. Alfa Chemistry - ISO 9001:32057 Certified.
Zardaverine
Zardaverine. Group: Biochemicals. Grades: Purified. CAS No. 101975-10-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Zardaverine
Zardaverine is an orally active and selective PDE3/4 inhibitor (IC50)=0.58 uM/0.17 uM) with potent bronchodilator activity. Zardaverine also selectively inhibits the proliferation of HCC cells and induces apoptosis and cycle arrest (G0/G1 phase). Zardaverine has good antitumor potential and is effective in both bronchial relaxation and reduction of inflammation in asthma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 101975-10-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15485.
Z-Arg-AMC
Z-Arg-AMC. CAS No. 62037-44-9. Molecular formula: C24H27N5O5. Mole weight: 465.51.
Z-Arg-Arg-7-amido-4-methylcoumarin hydrochloride
Z-Arg-Arg-7-amido-4-methylcoumarin hydrochloride. Uses: For analytical and research use. CAS No. 136132-67-7. Mole weight: 621.69. Catalog: AP136132677.
Z-Arg-Arg-AMC hydrochloride is a highly selective fluorescent Cathepsin B substrate. Z-Arg-Arg-AMC hydrochloride can be hydrolyzed by Cathepsin B to produce a fluorescent product for enzyme activity detection[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 136132-67-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-134434.
Z-Arg-Arg-pNA
Z-Arg-Arg-pNA is a substrate for cathepsin B and can be used to detect this enzyme activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 122630-71-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4500.
Z-Arg-Arg-pNA. 2 HCl
Z-Arg-Arg-pNA is a chromogenic substrate for cathepsin B and stem bromelain. Synonyms: Cathepsin B Ssubstrate I,colorimetric; Z-Arg-Arg-pNA dihydrochloride; benzyl (S)-5-guanidino-1-((S)-5-guanidino-1-(4-nitrophenylamino)-1-oxopentan-2-ylamino)-1-oxopentan-2-ylcarbamate dihydrochloride. CAS No. 201807-90-1. Molecular formula: C26H38Cl2N10O6. Mole weight: 657.55.
Z-Arg-Leu-Arg-Gly-Gly-AMC
Z-RLRGG-AMC is a fluorescent substrate for the deubiquitinating enzyme isopeptidase T (IPaseT) and other ubiquitin C-terminal hydrolase (UCH) based on the C-terminus of ubiquitin. CAS No. 167698-69-3. Molecular formula: C40H56N12O9. Mole weight: 848.96.
Z-Arg(Pmc)-OH.CHA. Group: Biochemicals. Grades: Highly Purified. CAS No. 112160-33-5. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C34H51N5O7S. US Biological Life Sciences.
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Z-Arg-SBzl
Z-Arg-SBzl is a substrate of both bovine and activated human protein C[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 88253-86-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5125.
Z-Arg(Z)2-OH
Z-Arg(Z)2-OH. Group: Biochemicals. Grades: Highly Purified. CAS No. 14611-34-8. Pack Sizes: 1g, 2g, 5g. US Biological Life Sciences.
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Zarutatug
Zarutatug (TORL-3-600 antibody) is an IgG1κ humanized antibody targeting cadherin 17 (CDH17). It selectively binds to cell-surface CDH17, triggering endocytosis and trafficking to lysosomes. Zarutatug can be used to construct ADCs, such as TORL-3-600[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TORL-3-600 antibody. CAS No. 3038456-02-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P991728.
Z-Asn-Gly-OH
Z-Asn-Gly-OH. Synonyms: Cbz-Asn-Gly-OH; N-benzyloxycarbonyl-L-asparagyl-glycine; Glycine, N-[N2-[(phenylmethoxy)carbonyl]-L-asparaginyl]-. Grade: ≥95% by HPLC. CAS No. 56675-97-9. Molecular formula: C14H17N3O6. Mole weight: 323.30.
Zasocitinib
Zasocitinib (NDI-034858) is a TYK2 inhibitor, target TYK2 JH2 domain with binding constant Kd of <200 pM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NDI-034858; TAK-279. CAS No. 2272904-53-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150096.
Z-Asp-CH2-DCB is a broad caspase inhibitor that blocks apoptosis by non-selectively inhibiting caspase activity. At 1-100 μM, it can dose-dependently block the production of IL-1β, TNF-α, IL-6, and IFN-γ by human peripheral blood mononuclear cells as well as inhibit T cell proliferation. Synonyms: ICE Inhibitor V; Z-Asp-[(2,6-dichlorobenzoyl)oxy]methane; Caspase-1 Inhibitor V; (3S)-5-(2,6-Dichlorobenzoyl)oxy-4-oxo-3-(phenylmethoxycarbonylamino)pentanoic acid. Grade: ≥98%. CAS No. 153088-73-4. Molecular formula: C20H17Cl2NO7. Mole weight: 454.3.
Z-Asp(OMe)-OH
Z-Asp(OMe)-OH. Group: Biochemicals. Grades: Highly Purified. CAS No. 3160-47-2. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences.
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z-Asp(otbu)-bromomethyl ketone
z-Asp(otbu)-bromomethyl ketone. CAS No. 153088-76-7. Product ID: ACM153088767. Molecular formula: C17H22BrNO5. Mole weight: 400.26. Alfa Chemistry - ISO 9001:32057 Certified.