A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Adrenochrome Impurity 2 is an impurity of Adrenochrome, which was first isolated from the products of an enzymatic oxidation. CAS No. 87708-46-1. Molecular formula: C9H9NO3. Mole weight: 179.17.
Adrenochrome monoaminoguanidine mesilate
Adrenochrome monoaminoguanidine mesilate. Group: Biochemicals. Alternative Names: 2- (1, 2, 3, 6-Tetra hydro-3- hydroxy-1- methyl -6-oxo-5H-indol-5-yl ide ne ) -hydrazinecarboximidam ide monomethanesulfonate salt; A-Peest; AMM. Grades: Highly Purified. CAS No. 4009-68-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C11H17N5O5S. US Biological Life Sciences.
Adrenocorticotropic hormone (ACTH; Adrenocorticotrophic hormone) is a polypeptide tropic hormone produced by the anterior pituitary gland. Adrenocorticotropic hormone stimulates cortisol secretion from the adrenal cortex via the hypothalamic-pituitary-adrenal (HPA) axis. Adrenocorticotropic hormone regulates cortisol and androgen production. Adrenocorticotropic hormone can promote the development of spermatogenesis. Adrenocorticotropic hormone can relieve acute inflammation in gout models by inhibiting the polarization of macrophages to M1 type, inhibiting ROS and proinflammatory factor production and protecting mitochondrial function. Adrenocorticotropic hormone can be used for the researches of inflammation, endocrinology, metabolic disease, such as gout and nephrotic syndrome[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACTH; Adrenocorticotrophic hormone. CAS No. 9002-60-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-106373.
Adrenocorticotropic hormone (1-39), rat
Adrenocorticotropic hormone (1-39), rat is a potent melanocortin 2 (MC2) receptor agonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ACTH(1-39), rat. CAS No. 77465-10-2. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P1477.
Adrenocorticotropic Hormone (ACTH) (1-39), human
Adrenocorticotropic Hormone (ACTH) (1-39), human is a melanocortin receptor agonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 1-39-Corticotropin (human). CAS No. 12279-41-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P1211.
Adrenocorticotropic Hormone Fragment 1-16 human, rat
ACTH (1-16) is an agonist of the melanocortin-1 and 3 receptors (K1 = 0.267 ± 0.116 and 19.0 ± 4.3 nmol/L respectively). Alternative Names: ACTH (1-16) (human); H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-OH. CAS No. 5576-42-1. Molecular formula: C89H133N25O22S. Mole weight: 1937.23.
Adrenocorticotropic Hormone Fragment 7-38 human
Adrenocorticotropic Hormone Fragment 7-38 human. Alternative Names: Corticostatin; (7-28)-Corticotropin; Acth(7-38); CIP peptide. CAS No. 68563-24-6. Molecular formula: C167H257N47O46. Mole weight: 3659.11.
adrenodoxin-NADP+ reductase
A flavoprotein (FAD). The enzyme, which transfers electrons from NADPH to adrenodoxin molecules, is the first component of the mitochondrial cytochrome P-450 electron transfer systems, and is involved in the biosynthesis of all steroid hormones. Group: Enzymes. Synonyms: adrenodoxin reductase; nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase; AdR; NADPH:adrenal ferredoxin oxidoreductase; NADPH-adrenodoxin reductase. Enzyme Commission Number: EC 1.18.1.6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1111; adrenodoxin-NADP+ reductase; EC 1.18.1.6; adrenodoxin reductase; nicotinamide adenine dinucleotide phosphate-adrenodoxin reductase; AdR; NADPH:adrenal ferredoxin oxidoreductase; NADPH-adrenodoxin reductase. Cat No: EXWM-1111.
Adrenomedullin (11-50), rat
Adrenomedullin (11-50), rat is the C-terminal fragment (11-50) of the adrenomedullin in rats. Rat adrenomedullin induces selective arterial vasodilation through CGRP1 receptor. Alternative Names: Ser-Thr-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Met-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Gly-Met-Ala-Pro-Arg-Asn-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2 (Disulfide bridge: Cys4-Cys9). Grades: ≥95%. CAS No. 163648-32-6. Molecular formula: C194H304N58O59S4. Mole weight: 4521.17.
Adrenomedullin (1-50), rat
Adrenomedullin (1-50), rat is a 50 amino acid peptide, which induces a selective arterial vasodilation via activation of CGRP1 receptor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Adrenomedullin (rat). CAS No. 161383-47-7. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P1534.
Adrenomedullin (1-50), rat
Adrenomedullin (1-50), rat, a 50-amino acid peptide, induces selective arterial vasodilation by activation of the CGRP1 receptor. Alternative Names: Tyr-Arg-Gln-Ser-Met-Asn-Gln-Gly-Ser-Arg-Ser-Thr-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Met-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Gly-Met-Ala-Pro-Arg-Asn-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2 (Disulfide bridge: Cys14-Cys19). Grades: ≥95%. Molecular formula: C248H381N77O75S5. Mole weight: 5729.50.
Adrenomedullin (1-52), human
Adrenomedullin is an antimicrobial peptide produced by adrenal medulla, skin, Homo sapiens (Human). It has antibacterial activity against Gram-positive and Gram-negative bacteria. In addition to controlling fluid-electrolyte homeostasis, adrenomedullin is an effective vasodilatory peptide hormone and can inhibit ACTH secretion of pituitary gland. Alternative Names: H-Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-Ser-Phe-Gly-Cys(1)-Arg-Phe-Gly-Thr-Cys(1)-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2; L-tyrosyl-L-arginyl-L-glutaminyl-L-seryl-L-methionyl-L-asparagyl-L-asparagyl-L-phenylalanyl-L-glutaminyl-glycyl-L-leucyl-L-arginyl-L-seryl-L-phenylalanyl-glycyl-L-cysteinyl-L-arginyl-L-phenylalanyl-glycyl-L-threonyl-L-cysteinyl-L-threonyl-L-valyl-L-glutaminyl-L-lysyl-L-leucyl-L-alanyl-L-histidyl-L-glutaminyl-L-isoleucyl-L-tyrosyl-L-glutaminyl-L-phenylalanyl-L-threonyl-L-alpha-aspartyl-L-lysyl-L-alpha-aspartyl-L-lysyl-L-alpha-aspartyl-L-asparagyl-L-valyl-L-alanyl-L-prolyl-L-arginyl-L-seryl-L-lysyl-L-isoleucyl-L-seryl-L-prolyl-L-glutaminyl-glycyl-L-tyrosinamide (16->21)-disulfide; Human adrenomedullin; Adrenomedullin (human); Human adrenomedullin-(1-52)-NH2. Grades: >95%. CAS No. 148498-78-6. Molecular formula: C264H406N80O77S3. Mole weight: 6028.82.
Adrenomedullin (16-31), human
Adrenomedullin (16-31), human is the 16-31 fragment of the amino acid residue of human adreomedullin (HADM). Alternative Names: H-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-NH2; L-cysteinyl-L-arginyl-L-phenylalanyl-glycyl-L-threonyl-L-cysteinyl-L-threonyl-L-valyl-L-glutaminyl-L-lysyl-L-leucyl-L-alanyl-L-histidyl-L-glutaminyl-L-isoleucyl-L-tyrosinamide (1->6)-disulfide. Grades: ≥95%. CAS No. 318480-38-5. Molecular formula: C82H129N25O21S2. Mole weight: 1865.19.
Adrenomedullin (AM) (13-52), human
Adrenomedullin (AM) (13-52), human is a 40-amino acid peptide that is used as an endothelium-dependent vasodilator agent and a high affinity ligand for the adrenomedullin receptor. Alternative Names: Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2 (Disulfide bridge: Cys16-Cys21). Grades: ≥95%. CAS No. 154765-05-6. Molecular formula: C200H308N58O59S2. Mole weight: 4533.13.
Adrenomedullin (AM) (13-52), human
Adrenomedullin (AM) (13-52), human is a 40 amino acid peptide, which acts as an endothelium-dependent vasodilator agent. Uses: Scientific research. Category: Peptides. CAS No. 154765-05-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1457.
Adrenomedullin (AM) (1-52), human
Adrenomedullin (AM) (1-52), human is a 52-amino acid peptide, which affects cell proliferation and angiogenesis in cancer. Uses: Scientific research. Category: Peptides. Alternative Names: Human adrenomedullin-(1-52)-NH2. CAS No. 148498-78-6. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P1455.
Adrenomedullin (AM) (1-52), human TFA
Adrenomedullin (AM) (1-52), human TFA is an adrenomedullin analogue with NH2 terminus truncation that affects cell proliferation and angiogenesis in cancer. Alternative Names: Human adrenomedullin-(1-52)-NH2 (TFA); Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg-Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2.TFA (Disulfide bridge: Cys16-Cys21). Grades: >98%. Molecular formula: C266H407F3N80O79S3. Mole weight: 6142.76.
Adrenomedullin (AM) (22-52), human
Adrenomedullin (AM) (22-52), human, an adrenomedullin analogue with NH2 terminus truncation, is an adrenomedullin receptor antagonist that also antagonizes calcitonin-generating peptide (CGRP) receptors in the vascular bed of the hindlimb of cats. Alternative Names: 22-52-Adrenomedullin (human); Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2; L-threonyl-L-valyl-L-glutaminyl-L-lysyl-L-leucyl-L-alanyl-L-histidyl-L-glutaminyl-L-isoleucyl-L-tyrosyl-L-glutaminyl-L-phenylalanyl-L-threonyl-L-alpha-aspartyl-L-lysyl-L-alpha-aspartyl-L-lysyl-L-alpha-aspartyl-L-asparagyl-L-valyl-L-alanyl-L-prolyl-L-arginyl-L-seryl-L-lysyl-L-isoleucyl-L-seryl-L-prolyl-L-glutaminyl-glycyl-L-tyrosinamide. Grades: ≥95%. CAS No. 159899-65-7. Molecular formula: C159H252N46O48. Mole weight: 3575.97.
Adrenomedullin (AM) (22-52), human
Adrenomedullin (AM) (22-52), human, an NH2 terminal truncated adrenomedullin analogue, is an adrenomedullin receptor antagonist, and also antagonizes the calcitonin generelated peptide (CGRP) receptor in the hindlimb vascular bed of the cat[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 22-52-Adrenomedullin (human). CAS No. 159899-65-7. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P1471.
Adrenomedullin (rat), a synthetic rat adrenomedullin (rADM), induces a potent and sustained hypotensive activity in anesthesized rats. Alternative Names: ADM (1-50) (rat); H-Tyr-Arg-Gln-Ser-Met-Asn-Gln-Gly-Ser-Arg-Ser-Thr-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Met-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Gly-Met-Ala-Pro-Arg-Asn-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2 (Disulfide bridge: Cys14-Cys19). Grades: ≥95%. CAS No. 161383-47-7. Molecular formula: C242H381N77O75S5. Mole weight: 5729.49.
Adrenorphin
Adrenorphin is an opioid octapeptide that acts as an agonist of μ-opioid receptor. Alternative Names: L-Valinamide, L-tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-L-arginyl-L-arginyl-; L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-L-arginyl-L-arginyl-L-valinamide; Adrenorphin (human); Adrenorphin (ox); BAM 8; Metaphinamide; Metorphamide; Metorphamide (ox); Metorphinamide; H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2. Grades: >95%. CAS No. 88377-68-8. Molecular formula: C44H69N15O9S. Mole weight: 984.18.
Adrenorphin TFA
Adrenorphin TFA is an opioid octapeptide that acts as an agonist of μ-opioid receptor with a Ki of 12 nM. Alternative Names: Adrenorphin (human), trifluoroacetate (salt); L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-L-arginyl-L-arginyl-L-valinamide trifluoroacetate; Adrenorphin (ox) trifluoroacetat; BAM 8 trifluoroacetate; Metaphinamide trifluoroacetate; Metorphamide trifluoroacetate; Metorphamide (ox) trifluoroacetate; Metorphinamide trifluoroacetate; H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2.TFA; Adrenorphin 3TFA. Grades: ≥95%. Molecular formula: C46H70F3N15O11S. Mole weight: 1098.22.
Adrenosterone
Steroid hormone with weak androgenic effects. Group: Biochemicals. Alternative Names: Androst-4-ene-3,11,17-trione; 11-Keto-4-androstene-3,17-dione; 11-Oxo-4-androstene-3,17-dione; Reichstein's substance G; NSC 12166. Grades: Highly Purified. CAS No. 382-45-6. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
Adrenosterone
Adrenosterone ((+)-Adrenosterone) is a competitive hydroxysteroid (11-beta) dehydrogenase 1 (HSD11β1) inhibitor.Adrenosterone is a steroid hormone with weak androgenic effect. Adrenosterone is a dietary supplement that can decrease fat and increase muscle mass. Adrenosterone acts as a suppressor of metastatic progression of human cancer cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-Adrenosterone. CAS No. 382-45-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g. Product ID: HY-17462.
Adrenosterone-d10
Adrenosterone-d10 ((+)-Adrenosterone-d10) is the deuterium labeled Adrenosterone (HY-17462). Adrenosterone ((+)-Adrenosterone) is a competitive hydroxysteroid (11-beta) dehydrogenase 1 (HSD11β1) inhibitor.Adrenosterone is a steroid hormone with weak androgenic effect. Adrenosterone is a dietary supplement that can decrease fat and increase muscle mass. Adrenosterone acts as a suppressor of metastatic progression of human cancer cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-Adrenosterone-d10. CAS No. 15807-37-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W721874.
Adropin (34-76) (human, mouse, rat)
Adropin (34-76) is a secretory domain of Adropin. Adropin (34-76) can inhibit cAMP level and glucose production in hepatocytes, and has a hypoglycemic effect. Adropin (34-76) plays an antifibrotic role by inhibiting the GLI1 signaling pathway[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1802086-30-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P4860.
Adropin (34-76) (human, mouse, rat)
Adropin, a secreted factor involved in energy homeostasis and lipid metabolism, is encoded by the energy homeostasis-related gene (Enho) and expressed in the liver and brain. In diet-induced obesity (DIO) mice, adropin (34-76) reduced hepatosteatosis and insulin resistance, regardless of obesity or food intake. In addition, adropin could be a regulator of endothelial function. Alternative Names: H-Cys-His-Ser-Arg-Ser-Ala-Asp-Val-Asp-Ser-Leu-Ser-Glu-Ser-Ser-Pro-Asn-Ser-Ser-Pro-Gly-Pro-Cys-Pro-Glu-Lys-Ala-Pro-Pro-Pro-Gln-Lys-Pro-Ser-His-Glu-Gly-Ser-Tyr-Leu-Leu-Gln-Pro-OH (Disulfide bridge: Cys1-Cys23); L-Cysteinyl-L-histidyl-L-seryl-L-arginyl-L-seryl-L-alanyl-L-alpha-aspartyl-L-valyl-L-alpha-aspartyl-L-seryl-L-leucyl-L-seryl-L-alpha-glutamyl-L-seryl-L-seryl-L-prolyl-L-asparaginyl-L-seryl-L-seryl-L-prolylglycyl-L-prolyl-L-cysteinyl-L-prolyl-L-alpha-glutamyl-L-lysyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-L-glutaminyl-L-lysyl-L-prolyl-L-seryl-L-histidyl-L-alpha-glutamylglycyl-L-seryl-L-tyrosyl-L-leucyl-L-leucyl-L-glutaminyl-L-proline cyclic (1→23)-disulfide. Grades: ≥95%. CAS No. 1802086-30-1. Molecular formula: C190H293N55O68S2. Mole weight: 4499.82.
ADS032
ADS032 is a sulfonylurea compound that is an NLRP1 and NLRP3 inflammasome inhibitor. ADS032 reduces the secretion of inflammatory factors and inhibits the oligomerization of ASC. ADS032 has anti-inflammatory effects in a variety of inflammatory models and can be used in the study of inflammatory diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2757333-37-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156798.
ADT-007
ADT-007 is a potent and orally active pan-RAS inhibitor with strong anticancer effects. ADT-007 binds RAS in a nucleotide-free conformation to block GTP activation. ADT-007 potently and selectively inhibits the growth of cancer cells with mutated or hyper-activated wild-type RAS isozymes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1945941-09-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-157887.
ADT-1004
ADT-1004 is an orally active prodrug of ADT-007 (HY-157887). ADT-007 is a reversible, highly potent and selective pan-RAS inhibitor that binds to the nucleotide-free conformation of RAS proteins and blocks their GTP activation, thereby inhibiting the downstream MAPK and AKT signaling pathways. ADT-1004 can be used for the research of pancreatic ductal adenocarcinoma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1945941-72-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-177106.
a-D-tetraacetylmannopyranoside-PEG3-bromide
Revolutionize your PEG Conjugations research with a-D-tetraacetylmannopyranoside-PEG3-bromide, a high-quality Sugar PEGs obtainable from CD Bioparticles Drug Delivery. Group: Sugar pegs.
a-D-Thiomannose sodium salt
A-D-Thiomannose sodium salt, hailed for its biomedicinal potential, is a chemical compound of great interest. Known for its participation in glycosylation and oligosaccharide synthesis, it is celebrated for its perceived therapeutic value in treating bacterial infections and preventing cancer. While much work remains to be done, it is a substance ripe for further exploration and experimentation. Alternative Names: α-D-Mannopyranose, 1-thio-, sodium salt (1:1); α-D-Mannopyranose, 1-thio-, monosodium salt. CAS No. 111057-34-2. Molecular formula: C6H11NaO5S. Mole weight: 218.21.
ADT-OH
ADT-OH is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. ADT is a putative neuroprotectant and antioxidant that increases glutathione levels in cultured astroglial cells. ADT-OH was shown to reduce tPA-enhanced Akt activation and VEGF expression in brain microvascular endothelial cells. Alternative Names: 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione; Desmethylanethol trithione; 3H-1,2-Dithiole-3-thione, 5-(4-hydroxyphenyl)-. CAS No. 18274-81-2. Molecular formula: C9H6OS3. Mole weight: 226.326.
AdTx1
AdTx1 is a high affinity, selective and non-competitive α1A adrenoceptor antagonist with Ki value of 0.35 nM. It is a 65 amino-acid peptide originally isolated from the venom of the green mamba. It is stabilized by four disulfide bridges and belongs to the family of the three-finger-fold peptide. It displays no significant activity against a range of other GPCRs. It antagonizes effects of phenylephrine on intra-urethral pressure in rats and on isolated rabbit prostate muscle in vitro. It is used as a potent relaxant of smooth muscles. Alternative Names: ρ-Da1a. Grades: >98%. Molecular formula: C310H481N87O100S8. Mole weight: 7283.22.
Aducanumab
Aducanumab (BIIB037) is a human monoclonal antibody that selectively targets aggregated amyloid-beta (Aβ). Aducanumab shows blood-brain-barrier penetration, and can be used for Alzheimer's disease (AD) research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIIB037. CAS No. 1384260-65-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P9967.
Aducanumab
Aducanumab is a human monoclonal antibody targeting amyloid-β (Aβ). Aducanumab has been approved for the treatment of Alzheimer's disease (AD). Alternative Names: BIIB037. CAS No. 1384260-65-4.
ADU-S100 disodium salt
ADU-S100 disodium salt (MIW815 disodium salt) is an activator of stimulator of interferon genes (STING) for treating cancer. Alternative Names: MIW815 disodium salt; ML RR-S2 CDA disodium salt; 2',3'-c-di-AM(PS)2 (Rp,Rp); Adenosine, [P(R)]-5'-O-[(R)-hydroxymercaptophosphinyl]-P-thioadenylyl-(2'→5')-, cyclic nucleotide, sodium salt (1:2); ADU-S 100; MIW 815. Grades: 98%. CAS No. 1638750-95-4. Molecular formula: C20H22N10Na2O10P2S2. Mole weight: 734.51.
Adustin
Akrabicin is an antibiotic produced in Streptomyces galactis against yeast and tinea mold. Alternative Names: (3-Hydroxy-2-furanyl)phenylmethanone; Methanone, (3-hydroxy-2-furanyl)phenyl-; (2E)-2-[hydroxy(phenyl)methylidene]furan-3-one; 2-Benzoyl-3-hydroxyfuran. CAS No. 69579-74-4. Molecular formula: C11H8O3. Mole weight: 188.18.
Advantame
Advantame is a combination of Aspartame (A790015) and Vanillin (V097500). Advantame was developed as a high-intensity, low calorie sweetener that is 20,000 times sweeter than sucrose. Group: Biochemicals. Grades: Highly Purified. CAS No. 245650-17-3. Pack Sizes: 10mg, 25mg. Molecular Formula: C24H30N2O7. US Biological Life Sciences.
Worldwide
Advantame
Advantame is an N-substituted derivative of aspartame. Advantame is a high-intensity, low calorie sweetener. Advantame can interact with plasma protein. Advantame has the potential to produce hypotension and inhibit hERG K+ channel to produce carditoxicity. Advantame binds to T1R2/T1R3 taste GPCR to form an oligomeric functional selectivity of biased heteromers with NMBR to induce a significant sialidase activity in vitro. Advantame has maternal toxicity (gastrointestinal disturbances) in the prenatal developmental toxicity study in rabbits[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 714229-20-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122351A.
ADWX 1
ADWX 1 has been found to be a Kv1.3 channel blocker and could probably ameliorate autoimmune encephalomyelitis at some extent. Alternative Names: ADWX1. Grades: >98%. Molecular formula: C169H281N57O46S7. Mole weight: 4071.86.
ADX 10059 hydrochloride
ADX 10059 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 757949-98-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
ADX-47273
ADX-47273 is a potent, selective and brain-penetrant mGluR5 positive allosteric modulator (PAM), with an EC50 of 0.17 μM for potentiation of glutamate (50 nM) response. ADX-47273 has antipsychotic and procognitive activities[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 851881-60-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13058.
ADX61623
ADX61623 is a potent follicle stimulating hormone (FSH) receptor (FSHR) negative allosteric modulator (NAM). ADX61623 shows luteinizing hormone receptor (LH-R) activity and is not active on thyroid-stimulating hormone (TSH) receptors. ADX61623 can be used for the study of estrogen dependent disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1067189-44-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-164764.
ADX71441
ADX71441 is an orally active, blood-brain barrier penetrant positive allosteric modulator of GABAB receptor. ADX71441 potentiates the activity of endogenous GABA at GABAB receptor, with an EC50 of 96 nM. ADX71441 functionally inhibits adenosine transporters and 5-HT2B receptor. ADX71441 produces anxiolytic-like, analgesic, muscle relaxant, hypothermic and overactive bladder inhibitory effects, reduces acute locomotor activity levels, decreases voluntary intake of alcohol and saccharin, attenuates stress-induced neuronal activation, and exhibits anti-hyperalgesic activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1207440-88-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118301.
ADX88178
ADX88178 is a potent metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) with an EC50 of 4 nM for human mGluR4. Uses: Scientific research. Category: Signaling pathways. CAS No. 1235318-89-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-18654.
Adxanthromycin A
Adxanthromycin A, a new inhibitor of ICAM-1/LFA-1 mediated cell adhesion from Streptomyces sp. NA-148. Molecular formula: C42H40O17. Mole weight: 816.76.
Adxanthromycin B
Adxanthromycin B, a new inhibitor of ICAM-1/LFA-1 mediated cell adhesion from Streptomyces sp. NA-148. Molecular formula: C48H50O22. Mole weight: 978.90.
a-D-Xylopyranosyl azide
a-D-Xylopyranosyl azide is a crucial compound in the research and development of various drugs targeting glycogen metabolism disorders and bacterial infections. With its azide group, a-D-Xylopyranosyl azide plays a vital role in drug discovery and development to combat diseases such as diabetes, cancer and compound-resistant infections. CAS No. 100842-21-5. Molecular formula: C5H9N3O4. Mole weight: 175.14.
Adynerigenin β-neritrioside
Adynerigenin β-neritrioside is a natural steroid found in the herbs of Nerium indicum Mill. Alternative Names: Adynerigenin beta-neritrioside. Grades: >95%. CAS No. 88721-09-9. Molecular formula: C42H64O17. Mole weight: 840.96.
Adynerin
Adynerin is a natural steroid found in the herbs of Nerium oleander. Uses: Scientific research. Category: Natural products. CAS No. 35109-93-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N2476.
AE105
AE105 is a 9-mer peptide probe targeting the urokinase-type plasminogen activator receptor (uPAR). AE105 binds tightly to the uPA-binding cavity of uPAR. AE105 can be used for the study of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 254729-66-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P11446.
AEBSF is a water-soluble, irreversible serine protease inhibitor that inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. Alternative Names: 4-(2-Aminoethyl)benzenesulfonyl fluoride hydrochloride; AEBSF hydrochloride; AEBSF. Grades: 98%. CAS No. 30827-99-7. Molecular formula: C8H11ClFNO2S. Mole weight: 239.69.
AEBSF hydrochloride
AEBSF hydrochloride is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. Uses: Scientific research. Category: Signaling pathways. CAS No. 30827-99-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg. Product ID: HY-12821.
AEC Red Substrate Kit, BioAssay (aminoethyl carbazole), Hydrogen Peroxide Solution (20X). Group: Molecular Biology. Pack Sizes: 12ml. US Biological Life Sciences.
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AEE788
AEE788 is an orally active inhibitor targeting EGFR and ErbB2 with IC50 values of 2 and 6 nM, respectively[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NVP-AEE 788. CAS No. 497839-62-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10045.
AEE 788
AEE 788. Group: Biochemicals. Grades: Purified. CAS No. 497839-62-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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AEE-788
AEE-788 is an orally bioavailable multiple-receptor tyrosine kinase inhibitor. AEE788 inhibits phosphorylation of the tyrosine kinases of epidermal growth factor receptor (EGFR), human epidermal growth factor receptor 2 (HER2), and vascular endothelial growth factor receptor 2 (VEGF2), resulting in receptor inhibition, the inhibition of cellular proliferation, and induction of tumor cell and tumor-associated endothelial cell apoptosis. Alternative Names: AEE 788; AEE788; 6-[4-[(4-ethylpiperazin-1-yl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine. Grades: >98%. CAS No. 497839-62-0. Molecular formula: C27H32N6. Mole weight: 440.595.
AEEA-AEEA
17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic acid is a complex organic molecule characterized by multiple functional groups and heteroatoms within its structure. It contains an amino group (-NH2) at the 17th position, a ketone group (oxo) at the 10th position, and several ether linkages (tetraoxa) throughout its carbon chain. Additionally, it features an amide linkage (aza) at the 9th position, which integrates nitrogen into the backbone. This compound is significant in biochemical and pharmaceutical research due to its potential applications in the design and synthesis of novel molecules with specific biological activities. Alternative Names: 17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecanoic acid; 8-Amino-3,6-dioxaoctanoic acid dimer; 17-Amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecan-1-oic acid; H-Adoa-Adoa-OH; H2N-PEG2-NH-PEG2-CH2COOH. Grades: ≥95%. CAS No. 1143516-05-5. Molecular formula: C12H24N2O7. Mole weight: 308.33.
AEG3482
AEG3482 is a potent antiapoptotic compound that inhibits Jun kinase (JNK) activity through induced expression of heat shock protein 70 (HSP70). AEG3482 directly binds HSP90, thereby facilitating HSF1-dependent expression of HSP70 and HSP25[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 63735-71-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107599.
AEG 3482
AEG 3482. Group: Biochemicals. Grades: Purified. CAS No. 63735-71-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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AEG 40730 dihydrochloride
AEG 40730 dihydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Aegeline
Aegeline. Group: Biochemicals. Alternative Names: (2E)-N-[2-Hydroxy-2-(4-methoxyphenyl)ethyl]-3-phenyl-2-propenamide; (E)-(±)-(2E)-N-[2-Hydroxy-2-(4-methoxyphenyl)ethyl]-3-phenyl-2-propenamide; Egeline; (±)-Aegeline; (±)-Egeline; Aegelin. Grades: Highly Purified. CAS No. 456-12-2. Pack Sizes: 50mg. Molecular Formula: C18H19NO3, Molecular Weight: 297.35. US Biological Life Sciences.
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Aegeline
Aegeline, is a compound that can be extracted from Aegle marmelos leaves, a tree that grows in India. Research has found the essential oil of the tree to be effective against 21 types of bacteria. Aegeline, has also shown to have anti-obesity effects. Alternative Names: (2E)-N-[2-Hydroxy-2-(4-methoxyphenyl)ethyl]-3-phenyl-2-propenamide; (E)-(±)-(2E)-N-[2-Hydroxy-2-(4-methoxyphenyl)ethyl]-3-phenyl-2-propenamide. Grades: > 95%. CAS No. 456-12-2. Molecular formula: C18H19NO3. Mole weight: 297.36.
Aegeline-d3
Aegeline-d3. Group: Biochemicals. Alternative Names: (2E)-N-[2-Hydroxy-2-(4-methoxyphenyl)ethyl]-3-phenyl-2-propenamide-d3; (E)-(±)-(2E)-N-[2-Hydroxy-2-(4-methoxyphenyl)ethyl]-3-phenyl-2-propenamide-d3; Egeline-d3; (±)-Aegeline-d3; (±)-Egeline-d3; Aegelin-d3. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C18H16D3NO3, Molecular Weight: 300.37. US Biological Life Sciences.