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| Product | Description | |
|---|---|---|
| Aerosol 22 | Aerosol 22. CAS No. 38916-42-6. Product ID: ACM38916426. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Aerosol Monitor, Polystyrene 25 mm, mixed cellulose esters, 0.8 μm, white, with pad | Aerosol Monitor, Polystyrene 25 mm, mixed cellulose esters, 0.8 μm, white, with pad. |  |
| Aerothionin | Aerothionin is a dimeric spiroisoxazoline derived from marine sponges that demonstrates antimycobacterial activity. Synonyms: (+)-aerothionin. Grade: ≥97%. CAS No. 28714-26-3. Molecular formula: C24H26Br4N4O8. Mole weight: 818.1. |  |
| Aeruginosin 865 | Aeruginosin 865 is isolated from terrestrial cyanobacterium Nostoc sp. Lukeová 30/93 with anti-inflammatory effect. It is the first aeruginosin-type peptide containing both a fatty acid and a carbohydrate moiety. Aeruginosin 865 inhibits translocation of NF-kB to the nucleus. Grade: >98.0%. CAS No. 1611990-01-2. Molecular formula: C41H64N6O14. Mole weight: 864.98. | |
| AES-135 | AES-135 is a hydroxamic acid-based pan-HDAC inhibitor with IC50s ranging from 190-1100 nM for HDAC3, HDAC6, HDAC8 and HDAC11. It prolongs the survival in an orthotopic mouse model of pancreatic cancer. Synonyms: Benzamide, 4-[[[4-(1,1-dimethylethyl)phenyl]methyl][2-[[(4-fluorophenyl)sulfonyl][(2,3,4,5,6-pentafluorophenyl)methyl]amino]acetyl]amino]-N-hydroxy-; 4-({N-[(4-Fluorophenyl)sulfonyl]-N-(pentafluorobenzyl)glycyl}[4-(2-methyl-2-propanyl)benzyl]amino)-N-hydroxybenzamide. Grade: ≥98%. CAS No. 2361659-61-0. Molecular formula: C33H29F6N3O5S. Mole weight: 693.66. | |
| AES-350 | AES-350 is an effective and orally active HDAC6 inhibitor with IC50 and Ki of 0.0244 μM and 0.035 μM, respectively. AES-350 shows higher HDAC isoform selectivity, higher MV4-11 cell cytotoxicity, improved treatment window and more effective absorption through cells and lipid membranes. Synonyms: Tert-Butylbenzamido Hydroxylbenzamide. Grade: 98%. CAS No. 847249-57-4. Molecular formula: C18H20N2O3. Mole weight: 312.4. | |
| Aescin A | Aescin A. Group: Biochemicals. CAS No. 123748-68-5. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Aescin B | Aescin B. Group: Biochemicals. CAS No. 26339-90-2. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Aescin C | Aescin C. Group: Biochemicals. CAS No. 219944-39-5. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Aescine | Aescine. Alternative Names: AESCINE, 6805-41-0. CAS No. 6805-41-0. Molecular formula: C55H86O24. Mole weight: 1131.26. Purity: Purity >95%. IUPAC Name: 6-[[(4S,6aR,6bS,8aR,14bR)-9-acetyloxy-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-10-(2-methylbut-2-enoyloxy)-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-4-hydroxy-3,5-bis[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-. SMILES: CC=C(C)C(=O)OC1C(C2(C(CC1(C)C)C3=CCC4C5(CCC(C(C5CCC4(C3(CC2O)C)C)(C)CO)OC6C(C(C(C(O6)C(=O)O)OC7C(C(C(C(O7)CO)O)O)O)O)OC8C(C(C(C(O8)CO)O)O)O)C)CO)OC(=O)C. | |
| Aescin polysulphate sodium salt | Aescin polysulphate sodium salt is a remarkable biomedical compound with anti-inflammatory and antithrombotic prowess acting as an exquisite derivative of Aescin. Molecular formula: C53H82O36S4. Mole weight: 1423.46. | |
| Aestivophoenin A | Aestivophoenin is a nerve cell protective substance produced in Streptomyces purpeofuscus. Aestivophoenin A can reduce the toxicity of L-glutamate to Nl8-RE-105 cells, with an ECso of 15.0 nmol/L, and has an antioxidant effect. CAS No. 171864-91-8. Molecular formula: C31H32N2O7. Mole weight: 544.59. | |
| Aestivophoenin B | Aestivophoenin is a nerve cell protective substance produced in Streptomyces purpeofuscus. Aestivophoenin B can reduce the toxicity of L-glutamate to Nl8-RE-105 cells, with an ECso of 6.2 nmol/L, and has an antioxidant effect. CAS No. 171864-92-9. Molecular formula: C36H40N2O7. Mole weight: 612.71. | |
| Aetoxylon sympetalum oil | Aetoxylon sympetalum oil. CAS No. 1333524-00-7. Product ID: FFC-AR-1333524007. Alfa Chemistry - ISO 9001:32057 Certified. | |
| AEW-541 | AEW541, also known as NVP-AEW541, is a novel, potent IGF-IR kinase inhibitor. NVP-AEW541 is capable of distinguishing between the IGF-IR (IC50 = 0.086 microM) and the closely related InsR (IC50 = 2.3 microM) in cells. NVP-AEW541 abrogates IGF-I-mediated survival and colony formation in soft agar at concentrations that are consistent with inhibition of IGF-IR autophosphorylation. NVP-AEW541 represents a class of selective, small molecule IGF-IR kinase inhibitors with proven in vivo antitumor activity and potential therapeutic application. Synonyms: NVP-AEW541; NVP-AEW 541; NVP-AEW-541; AEW-541; AEW 541; AEW541. Grade: 0.98. CAS No. 475489-16-8. Molecular formula: C27H29N5O. Mole weight: 439.563. | |
| AEZS-108 | AEZS-108, also known as AN-152 or zoptarelin doxorubicin, is a peptide agonist of the gonadotropin releasing hormone-1 receptor (GnRH-1R). Zoptarelin doxorubicin binds to GnRH-1Rs, which may be highly expressed on endometrial and ovarian tumor cell membrane surfaces, and is internalized. Once inside the cell, the doxorubicin moiety of this agent intercalates into DNA and inhibits the topoisomerase II activity, which may result in the inhibition of tumor cell DNA replication and tumor cell proliferation. Synonyms: AEZS 108; AEZS108; AN 152; AN-152; AN152; Zoptarelin doxorubicin; Zoptrex; Lys(6)-LHRH-doxorubicin. Grade: 98%. CAS No. 139570-93-7. Molecular formula: C91H117N19O26. Mole weight: 1893.01. | |
| AEZS-112 | AEZS-112, also known as ZEN012, is an orally active small mol. anti-cancer drug which inhibits the polymn. of tubulin at low micromolar concns. AEZS 112 dose-dependently increased non-vital hypodiploid cells and the cytotoxic effect was least pronounced in G2 phase of the cell cycle. AEZS 112 showed anti-tumor activity in human ovarian and endometrial cancer cell lines at low micromolar concns., which could not be abrogated by caspase inhibition and is therefore a good candidate for in vivo studies in these tumors. Synonyms: ZEN012; ZEN 012; ZEN-012; AEZS 112; AEZS112. Grade: 98%. CAS No. 1214741-69-1. Molecular formula: C25H23N3O2. Mole weight: 397.47. | |
| AF12198 | AF12198 is a potent, selective and specific peptide antagonist for human type I interleukin-1 receptor (IL1-R1) (IC50=8 nM) but not the human type II receptor (IC50=6.7 μM) or the murine type I receptor (IC50>200 μM). AF12198 inhibits IL-1-induced IL-8 production (IC50=25 nM) and IL-1-induced intercellular adhesion molecule-1 (ICAM-1) expression (IC50=9 nM) in vitro. AF12198 has anti-inflammatory activities and blocks responses to IL-1 in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 185413-30-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1110. |  |
| AF 12198 | AF 12198. Group: Biochemicals. Grades: Purified. CAS No. 185413-30-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| AF 12198 | It is a potent, selective human type I IL-1 receptor antagonist. Synonyms: N-Acetyl-L-phenylalanyl-L-α-glutamyl-L-tryptophyl-L-threonyl-L-prolylglycyl-L-tryptophyl-L-tyrosyl-L-glutaminyl-(2S)-2-azetidinecarbonyl-L-tyrosyl-L-alanyl-L-leucyl-L-prolyl-L-Leucinamide; Ac-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-L-azetidine-2-carbonyl-Tyr-Ala-Leu-Pro-Leu-NH2. Grade: >98%. CAS No. 185413-30-3. Molecular formula: C96H123N19O22. Mole weight: 1895.14. | |
| AF 12198 acetate | AF 12198 acetate is a potent, selective human type I IL-1 receptor antagonist. Synonyms: N-Acetyl-L-phenylalanyl-L-α-glutamyl-L-tryptophyl-L-threonyl-L-prolylglycyl-L-tryptophyl-L-tyrosyl-L-glutaminyl-(2S)-2-azetidinecarbonyl-L-tyrosyl-L-alanyl-L-leucyl-L-prolyl-L-leucinamide acetate; Ac-Phe-Glu-Trp-Thr-Pro-Gly-Trp-Tyr-Gln-Aze-Tyr-Ala-Leu-Pro-Leu-NH2.CH3CO2H; (N-(N-acetyl-L-phenylalanyl-L-alpha-glutamyl-L-tryptophyl-L-threonyl-L-prolyl-glycyl-L-tryptophyl-L-tyrosyl-L-glutaminyl)-(2S)-azetidine-2-carbonyl)-L-tyrosyl-L-alanyl-L-leucyl-L-prolyl-L-leucinamide acetate. Grade: ≥95%. Molecular formula: C98H127N19O24. Mole weight: 1955.17. | |
| AF3485 | AF3485 is a selective 3-aminocarbazole inhibitor of mPGES-1, blocking the synthesis of PGE2 but not PGF2α in A549 cells stimulated with IL-1β (IC50s = 2.9 and >100 μM, respectively). Synonyms: CAY10686; N-[9-(2-hydroxyethyl)carbazol-3-yl]-2-(trifluoromethyl)benzamide. Grade: ≥95%. CAS No. 1195786-61-8. Molecular formula: C22H17F3N2O2. Mole weight: 398.4. | |
| AF 353 | AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist. It is a highly potent inhibitor of α,β-meATP-evoked intracellular calcium flux in cell lines expressing recombinant rat and human P2X3 and human P2X2/3 channels. It also blocks human P2X2/3 channel function with marginally reduced potency (pIC50 = 7.3). It significantly reduces this parameter in both groups. It also reduces the inter-contractile interval in control but not in SCI rats. Synonyms: AF353; AF-353; 2,4-Pyrimidinediamine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]-; Ro 4; 5-{[5-iodo-2-(1-Methylethyl)-4-(Methyloxy)phenyl]oxy}-2,4-pyrimidinediamine. Grade: >98%. CAS No. 865305-30-2. Molecular formula: C14H17IN4O2. Mole weight: 400.21. | |
| AF-353 | AF-353 (Ro-4) is a potent, selective and orally bioavailable P2X3/P2X2/3 receptor antagonist, with a pIC50 of 8.0 for both human and rat P2X3, and with a pIC50 of 7.3 for human P2X2/3[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro-4. CAS No. 865305-30-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14483. | |
| AF38469 | AF38469 is a novel, selective, orally bioavailable Sortilin inhibitor and shows no activity against the NTR1 receptor. Synonyms: AF 38469; AF-384694. CAS No. 1531634-31-7. Molecular formula: C15H11F3N2O3. Mole weight: 324.25. | |
| AF38469 | AF38469 is a selective, orally bioavailable Sortilin inhibitor with an IC50 value of 330 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1531634-31-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12802. | |
| AF405 acid | AF405 acid is a fluorescent dye. AF405 exhibits a maximal excitation wavelength of 395 nm, and a maximal emission wavelength of 435 nm. AF405 is used for cell labeling and imaging[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 852953-60-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-D2445. | |
| AF488 NHS ester | AF488 NHS ester is an amine specific fluorescence probe (Em=525 nm). AF488 NHS ester reacts with sulfhydryl groups and amines in aqueous and biological samples then change their chemical structure and fluorescence properties after derivatization[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1374019-99-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D1730. | |
| AF615 | AF615 is a small molecule inhibitor targeting the CDT1/Geminin protein complex (IC50 = 0.313 μM). AF615 selectively induces DNA damage, inhibits DNA synthesis, causes cell cycle arrest, and decreases the survival rate in cancer cell lines. AF615 displayed a Ki = 0.37 μM in case of Geminin-tCDT1 interaction and a Ki = 0.75 μM in case of Geminin-miniCDT1 interaction[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 122510-61-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-171180. | |
| AF64394 | AF64394 is a GPR3 inverse agonist, with a pIC50 of 7.3. Uses: Scientific research. Category: Signaling pathways. CAS No. 1637300-25-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12664. | |
| AF64394 | AF64394 is a potent and selective GPR3 inverse agonist. Synonyms: AF 64394; AF-64394; N-(4-chloro-2-isopropoxybenzyl)-5-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine. Grade: >98%. CAS No. 1637300-25-4. Molecular formula: C21H20ClN5O. Mole weight: 393.87. | |
| AF647-NHS ester | AF647-NHS ester is an analog of Alexa Fluor 647 (AF647). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: Protect from light[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 407627-60-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-D1119. | |
| AF647-NHS ester triTEA | AF647-NHS ester is an analogue of Alexa Fluor 647 (AF647), which has excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 407627-61-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-D1119C. | |
| Afabicin | Afabicin is the prodrug of Debio1452 and an inhibitor FabI, an enzyme critical to fatty acid biosynthesis in staphylococci. Synonyms: Debio 1450; AFN-1720. CAS No. 1518800-35-5. Molecular formula: C23H24N3O7P. Mole weight: 485.43. | |
| Afacifenacin | Afacifenacin acts as a sodium/calcium exchanger inhibitor used in the prevention of reperfusion injury associated with restoration of coronary blood flow via surgery. Synonyms: (S)-(+)-3-[1-[3-(Trifluoromethoxy)benzyl]piperidin-4-yl]-4-phenyl-3,4-dihydro-1H-quinazolin-2-one. Grade: > 95%. CAS No. 877606-63-8. Molecular formula: C27H26F3N3O2. Mole weight: 481.52. | |
| A-factor | It is produced by the strain of streptomyces griseus. It can not only promote the formation of spores and air hyphae by streptomycin, but also restore the ability of non-production mutants to produce streptomycin, which is the so-called Autoregulator. Synonyms: 2-Isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone; Q27144309; SCHEMBL6026457; DTXSID00965600; 4-(HYDROXYMETHYL)-3-(6-METHYLHEPTANOYL)OXOLAN-2-ONE; 2(3H)-Furanone, dihydro-4-(hydroxymethyl)-3-(6-methyl-1-oxoheptyl)-, (4R)-; (-)-A factor; (R)-4-Hydroxymethyl-3-(6-methyl-heptanoyl)-dihydro-furan-2-one. CAS No. 51311-41-2. Molecular formula: C13H22O4. Mole weight: 242.31. | |
| Afamelanotide | Afamelanotide. Category: Active pharmaceutical ingredients. Grades: USDMF. CAS No. 75921-69-6. Product ID: API75921696. Molecular formula: C78H111N21O19. Mole weight: 1646.85. EINECS: 211-519-9. Standard: GMP. |  |
| Afasevikumab | Afasevikumab (RG 7624; RO 5553110; NI-1401) is a fully human monoclonal IgG1κ antibody neutralizing both IL-17A and IL-17F. Afasevikumab has anti-inflammatory activities[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RG 7624; RO 5553110; NI-1401. CAS No. 1589503-30-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99424. | |
| Afatinib | Afatinib (BIBW 2992) is an orally active, potent and irreversible dual specificity inhibitor of ErbB family (EGFR and HER2), with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively. Afatinib can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIBW 2992. CAS No. 850140-72-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-10261. | |
| Afatinib | Afatinib. Uses: For analytical and research use. Alternative Names: (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. CAS No. 850140-72-6. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. Catalog: APB850140726. |  |
| Afatinib | Afatinib irreversibly inhibits EGFR/HER2 including EGFR, EGFR(L858R), EGFR(L858R/T790M) and HER2. It is 100-fold more active against Gefitinib-resistant L858R-T790M EGFR mutant. Uses: Antineoplastic agents. Synonyms: 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-, (2E)-; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; BIBW 2992; Gilotrif; Giotrif; Tovok; (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Grade: >98%. CAS No. 850140-72-6. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. | |
| Afatinib (BIBW2992) | Afatinib inhibits EGFR / ErbB irreversibly in vitro with IC50 of 0.5, 0.4, 10, 14, 1 nM for EGFRwt, EGFR L858R , EGFR L858R/T790M ErbB2 (HER2) and ErbB4 (HER4), respectively. Afatinib induces autophagy. Group: Inhibitors. Alternative Names: BIBW2992. CAS No. 850140-72-6. Pack Sizes: 1g. Product ID: S1011. Formula: C24H25ClFN5O3. Smiles: CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| Afatinib-[d4] | Labelled Afatinib. Afatinib is a medication approved for the treatment of metastatic non-small cell lung cancer (NSCLC) that has certain EGFR mutations. It acts via inhibiting EGFR and HER2. Synonyms: (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; BIBW 2992. Grade: > 98%. Molecular formula: C24H21D4ClFN5O3. Mole weight: 489.97. | |
| Afatinib-[d6] | Afatinib-[d6] is the labelled analogue of Afatinib. Afatinib is a medication approved for the treatment of metastatic non-small cell lung cancer (NSCLC) that has certain EGFR mutations. It acts via inhibiting EGFR and HER2. Synonyms: Afatinib-d6; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide-d6; BIBW 2992-d6; Tovok-d6; Tomtovok-d6. Grade: 97%; ≥99% atom D. CAS No. 1313874-96-2. Molecular formula: C24H19D6ClFN5O3. Mole weight: 491.98. | |
| Afatinib D6 | Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor. Category: Active pharmaceutical ingredients. CAS No. 1313874-96-2. Product ID: API1313874962. Molecular formula: C24H25ClFN5O3. Mole weight: 491.98. | |
| Afatinib-[d6] Dimaleate | One of the isotopic labelled form of Afatinib Dimaleate, which could be used in the treatment of some cancer and diseases of espiratory tract. Synonyms: (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quizolinyl]-4-dimethylamino)-2-butemide Dimaleate. Grade: 95% by HPLC; 98% atom D. Molecular formula: C32H27D6ClFN5O11. Mole weight: 724.13. | |
| Afatinib dimaleate | Afatinib (BIBW 2992) dimaleate is an orally active, potent and irreversible dual specificity inhibitor of ErbB family (EGFR and HER2), with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively. Afatinib dimaleate can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIBW 2992MA2. CAS No. 850140-73-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-10261A. | |
| Afatinib dimaleate | Afatinib Dimaleate irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively. Synonyms: (2E)-N-[4-[(3,4-difluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide. Grade: >98%. CAS No. 850140-73-7. Molecular formula: C32H33ClFN5O11. Mole weight: 717.18. | |
| Afatinib impurity 10 | Afatinib impurity 10. Uses: For analytical and research use. CAS No. 2223677-63-0. Molecular formula: C24H25Cl2N5O3. Mole weight: 502.4. Catalog: APB2223677630. | |
| Afatinib impurity 11 | Afatinib impurity 11. Uses: For analytical and research use. CAS No. 2223677-62-9. Molecular formula: C24H25F2N5O3. Mole weight: 469.49. Catalog: APB2223677629. | |
| Afatinib impurity 11 | Afatinib impurity 11 is an impurity of Afatinib, which is an irreversible EGFR family inhibitor used to treat non-small cell lung cancer (NSCLC). Synonyms: 2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-; (S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)acrylamide; N-{4-[(3-Chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydro-3-furanyloxy]-6-quinazolinyl}acrylamide. Grade: ≥95%. CAS No. 1402086-20-7. Molecular formula: C21H18ClFN4O3. Mole weight: 428.84. | |
| Afatinib impurity 12 | Afatinib impurity 12. Uses: For analytical and research use. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. Catalog: APB10916. | |
| Afatinib impurity 13 | Afatinib impurity 13. Uses: For analytical and research use. CAS No. 2223677-64-1. Molecular formula: C22H20ClFN4O3. Mole weight: 442.88. Catalog: APB2223677641. | |
| Afatinib impurity 14 | Afatinib impurity 14. Uses: For analytical and research use. Alternative Names: (E)-4-isopropoxybut-2-enoic acid. Molecular formula: C7H12O3. Mole weight: 144.17. Catalog: APB02310. | |
| Afatinib impurity 14 | Afatinib impurity 14. Uses: For analytical and research use. CAS No. 1637254-93-3. Molecular formula: C22H19BrClFN4O3. Mole weight: 521.77. Catalog: APB1637254933. | |
| Afatinib impurity 15 | Afatinib impurity 15. Uses: For analytical and research use. Alternative Names: N1,N6-bis(3-chloro-4-fluorophenyl)-7-nitroisoquinoline-1,6-diamine. Molecular formula: C21H12Cl2F2N4O2. Mole weight: 461.25. Catalog: APB02309. | |
| Afatinib impurity 15 | Afatinib impurity 15. Uses: For analytical and research use. CAS No. 2413212-13-0. Molecular formula: C23H23ClFN5O3. Mole weight: 471.92. Catalog: APB2413212130. | |
| Afatinib impurity 16 | Afatinib impurity 16. Uses: For analytical and research use. Alternative Names: 7-fluoro-4-isopropoxy-6-nitroquinazoline. Molecular formula: C11H10FN3O3. Mole weight: 251.21. Catalog: APB02308. | |
| Afatinib impurity 17 | Afatinib impurity 17. Uses: For analytical and research use. Alternative Names: 1000397-30-7(HCl); 4-chloro-7-fluoro-6-nitroquinazoline. CAS No. 162012-70-6. Molecular formula: C8H3ClFN3O2. Mole weight: 227.58. Catalog: APB162012706. | |
| Afatinib impurity 18 | Afatinib impurity 18. Uses: For analytical and research use. Alternative Names: (S)-7-fluoro-6-nitro-4-((tetrahydrofuran-3-yl)oxy)quinazoline. Molecular formula: C12H10FN3O4. Mole weight: 279.22. Catalog: APB02307. | |
| Afatinib impurity 19 | Afatinib impurity 19. Uses: For analytical and research use. Alternative Names: N-(3,4-dichlorophenyl)-7-fluoro-6-nitroquinazolin-4-amine. Molecular formula: C14H7Cl2FN4O2. Mole weight: 353.14. Catalog: APB02306. | |
| Afatinib impurity 2 | Afatinib impurity 2. Uses: For analytical and research use. CAS No. 2413212-11-8. Molecular formula: C24H25ClFN5O4. Mole weight: 501.94. Catalog: APB2413212118. | |
| Afatinib Impurity 2 | An analogue of Afatinib. Synonyms: 7-Quinazolinol, 4-[(3-chloro-4-fluorophenyl)?amino]?-6-nitro-. Grade: > 95%. CAS No. 1449430-45-8. Molecular formula: C14H8ClFN4O3. Mole weight: 334.7. | |
| Afatinib impurity 20 | Afatinib impurity 20. Uses: For analytical and research use. Alternative Names: 6-nitro-4,7-bis(((S)-tetrahydrofuran-3-yl)oxy)quinazoline. Molecular formula: C16H17N3O6. Mole weight: 347.32. Catalog: APB02304. | |
| Afatinib impurity 20 | Afatinib impurity 20. Uses: For analytical and research use. CAS No. 1027929-81-2. Molecular formula: C8H4FN3O3. Mole weight: 209.14. Catalog: APB1027929812. | |
| Afatinib impurity 21 | Afatinib impurity 21. Uses: For analytical and research use. Alternative Names: N-(3-chloro-4-(((S)-tetrahydrofuran-3-yl)oxy)phenyl)-6-nitro-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-4-amine. Molecular formula: C22H21ClN4O6. Mole weight: 472.88. Catalog: APB02305. | |
| Afatinib impurity 22 | Afatinib impurity 22. Uses: For analytical and research use. Alternative Names: (S)-4-isopropoxy-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazoline. Molecular formula: C15H17N3O5. Mole weight: 319.31. Catalog: APB02302. | |
| Afatinib impurity 23 | Afatinib impurity 23. Uses: For analytical and research use. Alternative Names: (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-isopropoxybut-2-enamide. Molecular formula: C25H26ClFN4O4. Mole weight: 500.95. Catalog: APB02301. | |
| Afatinib impurity 24 | Afatinib impurity 24. Uses: For analytical and research use. Alternative Names: (S,E)-4-(dimethylamino)-N-(4-((4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide. Molecular formula: C24H26FN5O3. Mole weight: 451.49. Catalog: APB02303. | |
| Afatinib impurity 25 | Afatinib impurity 25. Uses: For analytical and research use. Alternative Names: 4-((3-chloro-4-fluorophenyl)amino)-6-(2-hydroxy-5-oxopyrrolidin-1-yl)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazoline 1-oxide. Molecular formula: C22H20ClFN4O5. Mole weight: 474.87. Catalog: APB02299. | |
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