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| Product | Description | |
|---|---|---|
| Afatinib impurity A | Afatinib impurity A. Uses: For analytical and research use. Alternative Names: (S)-N-(3-chloro-4-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine. Molecular formula: C18H14ClFN4O4. Mole weight: 404.78. Catalog: APB02321. |  |
| Afatinib Impurity A | An analogue of Afatinib. Synonyms: 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)?-6-nitro-7-[[(3R)?-tetrahydro-3-furanyl]?oxy]?-. Grade: > 95%. CAS No. 402855-07-6. Molecular formula: C18H14ClFN4O4. Mole weight: 404.79. |  |
| Afatinib Impurity AFT-8 | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Afatinib Impurity QJJ; N-[4-((3-Chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutenamide; Butanamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-3-hydroxy-. Grade: ≥95%. CAS No. 2323570-72-3. Molecular formula: C24H27ClFN5O4. Mole weight: 503.95. | |
| Afatinib impurity B | Afatinib impurity B. Uses: For analytical and research use. Alternative Names: (S)-N4-(3-chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine. CAS No. 314771-76-1. Molecular formula: C18H16ClFN4O2. Mole weight: 374.8. Catalog: APB314771761. | |
| Afatinib Impurity B | An analogue of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl; N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine; (S)-N4-(3-Chloro-4-fluorophenyl)-7-((tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine. Grade: > 95%. CAS No. 314771-76-1. Molecular formula: C18H16ClFN4O2. Mole weight: 374.81. | |
| Afatinib impurity C | Afatinib impurity C. Uses: For analytical and research use. Alternative Names: (R,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. CAS No. 945553-91-3. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. Catalog: APB945553913. | |
| Afatinib Impurity C | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)?amino]?-7-[[(3R)?-tetrahydro-3-furanyl]?oxy]?-6-quinazolinyl]?-4-(dimethylamino)?-, (2E)?-. Grade: > 95%. CAS No. 945553-91-3. Molecular formula: C24H25ClFN5O3. Mole weight: 485.95. | |
| Afatinib Impurity CSEJXA | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (S)-N1-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-N2,N2-dimethyloxalamide (Afatinib Impurity; (S)-N1-(4-((3-CHLORO-4-FLUOROPHENYL)AMINO)-7-((TETRAHYDROFURAN-3-YL)OXY)QUINAZOLIN-6-YL)-N2,N2-DIMETHYLOXALAMIDE; Afatinib Impurity CSEJXA; CS-0164258; E82032; (S)-N1-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-N2,N2-dimethyloxalamide (Afatinib Impurity pound(c). Grade: ≥95%. CAS No. 2223677-66-3. Molecular formula: C22H21ClFN5O4. Mole weight: 473.88. | |
| Afatinib Impurity CSZ | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grade: ≥95%. Molecular formula: C22H20ClFN4O5. Mole weight: 474.87. | |
| Afatinib impurity D | Afatinib impurity D. Uses: For analytical and research use. Alternative Names: (S,Z)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide; Z-Afatinib. CAS No. 1680184-59-1. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. Catalog: APB1680184591. | |
| Afatinib Impurity D | An analogue of Afatinib, a medication indicated for the treatment of non-small cell lung carcinoma (NSCLC). Synonyms: (2Z)-Afatinib; Z-Afatinib; (S,Z)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Grade: > 95%. CAS No. 1680184-59-1. Molecular formula: C24H25ClFN5O3. Mole weight: 485.95. | |
| Afatinib impurity E | Afatinib impurity E. Uses: For analytical and research use. Alternative Names: (S,E)-N-(4-((3,4-dichlorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Molecular formula: C24H25Cl2N5O3. Mole weight: 502.39. Catalog: APB02319. | |
| Afatinib Impurity ESS | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grade: ≥95%. Molecular formula: C30H34ClFN6O4. Mole weight: 597.09. | |
| Afatinib impurity F | Afatinib impurity F. Uses: For analytical and research use. Alternative Names: (S,E)-N-(4-((3,4-difluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Molecular formula: C24H25F2N5O3. Mole weight: 469.48. Catalog: APB02318. | |
| Afatinib impurity G | Afatinib impurity G. Uses: For analytical and research use. Alternative Names: (S,E)-N-(4-((4-chloro-3-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. Catalog: APB02317. | |
| Afatinib impurity H | Afatinib impurity H. Uses: For analytical and research use. Alternative Names: (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide. Molecular formula: C22H20ClFN4O3. Mole weight: 442.87. Catalog: APB02316. | |
| Afatinib impurity I | Afatinib impurity I. Uses: For analytical and research use. Alternative Names: (S,E)-4-bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide. Molecular formula: C22H19BrClFN4O3. Mole weight: 521.77. Catalog: APB02315. | |
| Afatinib Impurity I | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: Bromo-Afatinib; (S,E)-4-bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide. Grade: ≥95%. CAS No. 1637254-93-3. Molecular formula: C22H19BrClFN4O3. Mole weight: 521.78. | |
| Afatinib impurity J | Afatinib impurity J. Uses: For analytical and research use. Alternative Names: (S,E)-4-(dimethylamino)-N-(4-hydroxy-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide. Molecular formula: C18H22N4O4. Mole weight: 358.39. Catalog: APB02314. | |
| Afatinib Impurity J | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (2E)-N-[3,4-Dihydro-4-oxo-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide; (S,E)-4-(DIMETHYLAMINO)-N-(4-HYDROXY-7-((TETRAHYDROFURAN-3-YL)OXY)QUINAZOLIN-6-YL)BUT-2-ENAMIDE; (S,e)-4-(dimethylamino)-N-(4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-enamide; Afatinib Impurity J; SCHEMBL17352060; SCHEMBL17352063; GSUSIQVMAQBROU-PCAWENJQSA-N; CS-0164268; E82037; (S,E)-4-(Dimethylamino)-N-(4-hydroxy-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide (Afatinib Impurity). Grade: > 95%. CAS No. 1456696-14-2. Molecular formula: C18H22N4O4. Mole weight: 358.4. | |
| Afatinib Impurity JXH | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]formamide; Des(N,N-Dimethylprop-2-enyl-1-Amine) Afatinib. Grade: ≥95%. CAS No. 2223677-60-7. Molecular formula: C19H16ClFN4O3. Mole weight: 402.81. | |
| Afatinib impurity K | Afatinib impurity K. Uses: For analytical and research use. Alternative Names: (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(methylamino)but-2-enamide. Molecular formula: C23H23ClFN5O3. Mole weight: 471.91. Catalog: APB02313. | |
| Afatinib impurity L | Afatinib impurity L. Uses: For analytical and research use. Alternative Names: (S,E)-4-((4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-N,N-dimethyl-4-oxobut-2-en-1-amine oxide; Afatinib N-Oxide. Molecular formula: C24H25ClFN5O4. Mole weight: 501.94. Catalog: APB02311. | |
| Afatinib impurity M | Afatinib impurity M. Uses: For analytical and research use. Alternative Names: N-(4-chloro-3-fluorophenyl)-6-fluoro-7-nitronaphthalen-1-amine. Molecular formula: C16H9ClF2N2O2. Mole weight: 334.7. Catalog: APB02312. | |
| Afatinib impurity MLJ | Afatinib impurity MLJ. Uses: For analytical and research use. Alternative Names: (Z)-4-((4-((4-((3-chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-1-(dimethylamino)-4-oxobutan-2-yl)oxy)-4-oxobut-2-enoic acid. Molecular formula: C28H29ClFN5O7. Mole weight: 602.01. Catalog: APB02597. | |
| Afatinib Impurity N-Oxide | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (S,E)-4-((4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-N,N-dimethyl-4-oxobut-2-en-1-amine oxide. Grade: ≥95%. CAS No. 2413212-11-8. Molecular formula: C24H25ClFN5O4. Mole weight: 501.94. | |
| Afatinib Impurity O | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (S,E)-4-broMo-N-(4-((3-chloro-4-fluorophenyl)aMino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enaMide; (E)-4-bromo-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]but-2-enamide; Bromo-Afatinib; C22H19BrClFN4O3; AFATINIB IMPURITY O; SCHEMBL16398947; SCHEMBL16398952; IQJWAIKYBNTYPG-YUKKFKLSSA-N; CS-0164267; (2E)-4-Bromo-N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-2-butenamide; (S,E)-4-Bromo-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide (Afatinib Impurity). Grade: ≥95%. Molecular formula: C18H15FN4O4. Mole weight: 370.34. | |
| Afatinib impurity ODQ | Afatinib impurity ODQ. Uses: For analytical and research use. Alternative Names: (S)-6,6'-((E)-diazene-1,2-diyl)bis(N-(3-chloro-4-fluorophenyl)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-4-amine). Molecular formula: C36H28Cl2F2N8O4. Mole weight: 745.56. Catalog: APB02274. | |
| Afatinib impurity OLQ | Afatinib impurity OLQ. Uses: For analytical and research use. Alternative Names: (S)-6,6'-(hydrazine-1,2-diyl)bis(N-(3-chloro-4-fluorophenyl)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-4-amine). Molecular formula: C36H30Cl2F2N8O4. Mole weight: 747.58. Catalog: APB02273. | |
| Afatinib impurity OYQ | Afatinib impurity OYQ. Uses: For analytical and research use. Alternative Names: (Z)-1,2-bis(4-((3-chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)diazene oxide. Molecular formula: C36H28Cl2F2N8O5. Mole weight: 761.56. Catalog: APB02272. | |
| Afatinib Impurity Q | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grade: ≥95%. Molecular formula: C14H7ClF2N4O2. Mole weight: 336.68. | |
| Afatinib Impurity QA | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grade: ≥95%. Molecular formula: C18H16ClFN4O3. Mole weight: 390.80. | |
| Afatinib impurity QAQ | Afatinib impurity QAQ. Uses: For analytical and research use. Alternative Names: (S)-N-(3-chloro-4-fluorophenyl)-6-(hydroxyamino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine. Molecular formula: C18H16ClFN4O3. Mole weight: 390.8. Catalog: APB02275. | |
| Afatinib impurity QJJ | Afatinib impurity QJJ. Uses: For analytical and research use. Alternative Names: N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)-3-hydroxybutanamide. CAS No. 2323570-72-3. Molecular formula: C24H27ClFN5O4. Mole weight: 503.95. Catalog: APB2323570723. | |
| Afatinib Impurity SCl | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: (S,E)-N-(4-((3,4-Dichlorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Grade: ≥95%. CAS No. 2223677-63-0. Molecular formula: C24H25Cl2N5O3. Mole weight: 502.39. | |
| Afatinib impurity SHO | Afatinib impurity SHO. Uses: For analytical and research use. Alternative Names: N1,N2-bis(4-((3-chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)oxalamide. CAS No. 2223677-65-2. Molecular formula: C38H30Cl2F2N8O6. Mole weight: 803.6. Catalog: APB2223677652. | |
| Afatinib Impurity SM2A | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 2-Butenamide, 4-(dimethylamino)-N,N-dimethyl-. Grade: ≥95%. CAS No. 1862246-17-0. Molecular formula: C8H16N2O. Mole weight: 156.23. | |
| Afatinib Impurity WZYGNH2 | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grade: ≥95%. Molecular formula: C18H16ClFN4O2. Mole weight: 370.80. | |
| Afatinib Impurity WZYGNO2 | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Grade: ≥95%. Molecular formula: C18H14ClFN4O4. Mole weight: 404.78. | |
| Afatinib impurity YHQ | Afatinib impurity YHQ. Uses: For analytical and research use. Alternative Names: (S)-N-(3-chloro-4-fluorophenyl)-6-nitroso-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine. Molecular formula: C18H14ClFN4O3. Mole weight: 388.78. Catalog: APB02276. | |
| Afatinib oxalate | Afatinib (BIBW 2992) oxalate is an irreversible, orally active bispecific inhibitor of the ErbB family (EGFR and HER2) with IC50 values of 0.5 nM for EGFRwt, 0.4 nM for EGFRL858R, 10 nM for EGFRL858R/T790M, and 14 nM for HER2. Afatinib oxalate can be used to study esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC), and gastric cancer. Category: Active pharmaceutical ingredients. CAS No. 1398312-64-5. Product ID: API1398312645. Molecular formula: C28H29ClFN5O11. Mole weight: 666.01. |  |
| Afatinib (Standard) | Afatinib (Standard) is the analytical standard of Afatinib. This product is intended for research and analytical applications. Afatinib (BIBW 2992) is an orally active, potent and irreversible dual specificity inhibitor of ErbB family (EGFR and HER2), with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively. Afatinib can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIBW 2992 (Standard). CAS No. 850140-72-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10261R. |  |
| AFB-guanine | AFB-guanine. Group: Biochemicals. Alternative Names: (6aS, 8R, 9R, 9aR)-8-(2-Amino-1, 6-dihydro-6-oxo-7H-purin-7-yl)-2, 3, 6a, 8, 9, 9a-hexahydro-9-hydroxy-4-methoxy-cyclopenta[c]furo[3', 2':4, 5]furo[2, 3-h][1]benzopyran-1, 11-dione. Grades: Highly Purified. CAS No. 63425-04-7. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C22H17N5O8. US Biological Life Sciences. |  Worldwide |
| AFB-Guanine-13C,15N2 | A labelled guanine adduct of Aflatoxin B1. Synonyms: (6aS,8R,9R,9aR)-8-(2-Amino-1,6-dihydro-6-oxo-7H-purin-7-yl)-2,3,6a,8,9,9a-hexahydro-9-hydroxy-4-methoxy-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione-13C,15N2. Molecular formula: C21[13C]H17N3[15N]2O8. Mole weight: 482.38. | |
| AFB-Guanine Acetic Acid Salt | Acetic acid of a guanine adduct of Aflatoxin B1. Synonyms: (6aS,8R,9R,9aR)-8-(2-Amino-1,6-dihydro-6-oxo-7H-purin-7-yl)-2,3,6a,8,9,9a-hexahydro-9-hydroxy-4-methoxy-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione Acetic Acid. Grade: 95%. Molecular formula: C24H21N5O10. Mole weight: 539.45. | |
| AF-DX 116 | AF-DX 116 has been found to be a selective mAChR M2 antagonist. Synonyms: Otenzepad; AF-DX 116; AF-DX-116; AF-DX116; 11-[[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one. Grade: ≥98% by HPLC. CAS No. 102394-31-0. Molecular formula: C24H31N5O2. Mole weight: 421.54. | |
| AF-DX 384 | AF-DX 384 has been found to be a mAChR M2/M4 selective antagonist. Uses: Parasympatholytics. Synonyms: N-[2-[2-[(Dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide. Grade: ≥98% by HPLC. CAS No. 118290-26-9. Molecular formula: C27H38N6O2. Mole weight: 478.64. | |
| AF-DX 384 | AF-DX 384. Group: Biochemicals. Grades: Purified. CAS No. 118290-26-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Afegostat D-Tartrate | Afegostat D-Tartrate is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum (ER) with high affinity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-Isofagomine D-Tartrate; Isofagomine D-Tartrate. CAS No. 957230-65-8. Pack Sizes: 1 mg. Product ID: HY-14829E. | |
| Afe I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (BamHI-digest) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 80% of dna pbr322 fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. AGC↑GCT TCG↓CGA. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer B, BSA. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned Afe I gene from Alcaligenes faecalis T2774. Pack: 10 mM Tris-HCl (pH 7.6); 50 mM NaCl; 0.1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1014EN. |  |
| Afelimomab | Afelimomab is a mouse monoclonal antibody directed against TNFα. Afelimomab has been used in the research of sepsis treatment. Synonyms: MAK-195F; MAK 195F; MAK195F. Grade: 95%. CAS No. 156227-98-4. | |
| AFG206 | AFG206 is the novel first-generation "type II" FLT3 inhibitor. Synonyms: AFG-206; AFG 206. Grade: >98%. CAS No. 630122-37-1. Molecular formula: C20H19N3O2. Mole weight: 333.38. | |
| AFG210 | AFG210 is a novel first-generation "type II" FLT3 inhibitor. Synonyms: AFG 210; AFG-210; 1-(3-(trifluoromethyl)phenyl)-3-(4-(pyridin-4-yloxy)phenyl)urea. Grade: >98%. CAS No. 228400-22-4. Molecular formula: C19H14F3N3O2. Mole weight: 373.33. | |
| Aficamten | Aficamten is a next-generation cardiac myosin inhibitor with IC50 of 1.4 μM, for the treatment of symptomatic obstructive hypertrophic cardiomyopathy. Synonyms: CK 3773274; CK-3773274; CK3773274; CK-274. CAS No. 2364554-48-1. Molecular formula: C18H19N5O2. Mole weight: 337.38. | |
| Aficamten | Aficamten (CK-274) is a potent cardiac myosin inhibitor with an IC50 of 1.4 μM. Aficamten can be used for the research of hypertrophic cardiomyopathy (HCM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CK-274; CK-3773274. CAS No. 2364554-48-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139465. | |
| Afidopyropen | Afidopyropen (ME-5343) is an Afidopyropen targets sucking insects such as whiteflies, aphids, and leafhoppers by acting on the Nanchung (Nan) and Inactive (Iav) encoding gene of insects, and affecting TRPV channel. Afidopyropen can be used for many crops for its degradability[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ME-5343. CAS No. 915972-17-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124449. | |
| Afimetoran | Afimetoran (BMS-986256) is an orally active, selective, and highly bioavailable TLR7/8 antagonist. Afimetoran (BMS-986256) can inhibit TLR7/8 activation of the NF-κB pathway and reverse TLR7 mediated resistance to steroid induced apoptosis in plasma cell like dendritic cells (pDCs). Afimetoran (BMS-986256) can be used for research on inflammation and autoimmune diseases (systemic lupus erythematosus)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-986256. CAS No. 2171019-55-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139567. | |
| Afimetoran | Afimetoran is an orally active toll-like receptor 7 and 8 (TLR7/8) dual antagonist that can be used to study inflammatory and autoimmune diseases. Synonyms: BMS-986256; 1-Piperidineacetamide, 4-[2-(7,8-dimethyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)-3-(1-methylethyl)-1H-indol-5-yl]-; 2-(4-(2-(7,8-Dimethyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-3-isopropyl-1H-indol-5-yl)piperidin-1-yl)acetamide. Grade: ≥98%. CAS No. 2171019-55-7. Molecular formula: C26H32N6O. Mole weight: 444.57. | |
| Afimkibart | Afimkibart (PF-06480605; RVT-3101) is a fully human monoclonal antibody that selectively inhibits trimeric tumor necrosis factor-like ligand 1A (TL1A). Afimkibart neutralizes active trimeric TL1A, blocks TL1A-induced signaling pathways. Afimkibart inhibits NF-κB activation and IFN-γ production. Afimkibart can be used for the research of inflammatory bowel disease[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-06480605; RVT-3101. CAS No. 2911580-96-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P990876. | |
| Afimoxifene | Afimoxifene (4-hydroxytamoxifen) is a selective estrogen receptor modulator which is the active metabolite of tamoxifen. Afimoxifene is a transdermal gel formulation and is being developed by Ascend Therapeutics, Inc. under the trademark TamoGel. Afimoxifene has completed a phase II clinical trial for the treatment of cyclical mastalgia. Uses: Estrogen antagonists. Synonyms: (E/Z)-4-Hydroxytamoxifen; 4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol; TamoGel; Phenol, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-. Grade: ≥95%. CAS No. 68392-35-8. Molecular formula: C26H29NO2. Mole weight: 387.51. | |
| Afizagabar | Afizagabar (S44819) is a first-in-class, competitive, and selective antagonist at the GABA-binding site of the α5-GABAAR, with an IC50 of 585 nM for α5β2γ2 and a Ki of 66 nM for α5β3γ2. Afizagabar enhances hippocampal synaptic plasticity and exhibits pro-cognitive efficacy[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S44819; Egis-13529. CAS No. 1398496-82-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120051. | |
| Aflastatin A | It is produced by the strain of Streptomyces sp. MRI 142. Aflatoxin A has anti-Gram-positive bacteria, Pyricularia oryzae and yeast activity (MIC is 0.19-0.39 μg/mL), and inhibits the growth of adenocarcinoma 755 (1.0 mg/kg reduces tumor growth by 75% the above). Synonyms: 2,4-Pyrrolidinedione, 1,5-dimethyl-3-(1,8,9,11,13,15,17,19,21,23,25,27,28,29,30,31-hexadecahydroxy-2,4,6,10,12,14,18,20-octamethyl-32-(tetrahydro-3,4,5,6-tetrahydroxy-6-(2-hydroxyundecyl)-2H-pyran-2-yl)-2-dotriacontenylidene)-; LS-137668. Grade: ≥ 95%. CAS No. 179729-59-0. Molecular formula: C62H115NO24. Mole weight: 1258.56. | |
| Aflatoxicol | The 2 ppm acetonitrile solution of aflatoxicol, a metabolite of aflatoxin, could be commonly used as a standard solution. Uses: Only to be used as a reference standard in analytical laboratories. Synonyms: Aflatoxin Ro; (1S-(1alpha,6abeta,9abeta))-2,3,6a,9a-Tetrahydro-1-hydroxy-4-methoxycyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-11(1H)-one; Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-11(1H)-one, 2,3,6a,9a-tetrahydro-1-hydroxy-4-methoxy-, (1S,6aR,9aS)-; AFL. Grade: ≥98%. CAS No. 29611-03-8. Molecular formula: C17H14O6. Mole weight: 314.29. | |
| Aflatoxin B1-[13C17] | Aflatoxin B1-[13C17] is the labelled analogue of Aflatoxin B1, which is an aflatoxin produced by Aspergillus flavus and A. parasiticus. Synonyms: Aflatoxin B1-13C17. Grade: 95% atom 13C. CAS No. 1217449-45-0. Molecular formula: [13C]17H12O6. Mole weight: 329.15. | |
| Aflatoxin B1-13C-d3 | Aflatoxin B1 labelled standard. Synonyms: (6aR,9aS)-2,3,6a,9a-Tetrahydro-4-(methoxy)-1H,11H-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione-13C,d3; (-)-Aflatoxin B1-13C,d3. Grade: > 95%. Molecular formula: C17H9O6D3. Mole weight: 316.29. | |
| Aflatoxin B1 aldehyde reductase member 2 from Human, Recombinant | Aflatoxin B1 aldehyde reductase member 2 catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. Group: Enzymes. Synonyms: AFB1 aldehyde reductase 1; AFB1-AR 1; Aldoketoreductase 7; Succinic semialdehyde reductase. Enzyme Commission Number: EC 1.1.1.n11. AKR7A2. Mole weight: 39588.9 Da. Source: Human. AFB1 aldehyde reductase 1; AFB1-AR 1; Aldoketoreductase 7; Succinic semialdehyde reductase; EC 1.1.1.n11; AKR7A2; Aflatoxin B1 aldehyde reductase member 2. Cat No: NATE-1196. | |
| Aflatoxin B2 | Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects. Group: Biochemicals. Alternative Names: (6aR, 9aS) -2, 3, 6a, 8, 9, 9a-Hexahydro-4-methoxycyclopenta [c]furo [3, 2: 4, 5]furo [2, 3-h] [1]benzopyran-1, 11-dione; Dihydroaflatoxin B1; Dihydroaflatoxine B1. Grades: Highly Purified. CAS No. 7220-81-7. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| Aflatoxin B2-[13C17] | Aflatoxin B2-[13C17] is the labelled analogue of Aflatoxin B2, which is a mycotoxin found in A. terricola. Synonyms: Aflatoxin B2-13C17; (3S,7R)-11-methoxy-6,8,19-trioxapentacyclo[10.7.0.02,9.03,7.013,17]nonadeca-1,9,11,13(17)-tetraene-16,18-dione-13C17; Dihydroaflatoxine B1-13C17; 2,3,6aR,8,9,9aS-hexahydro-4-methoxy-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione-13C17; Fully 13C-labelled Aflatoxin B2. Grade: ≥95%. CAS No. 1217470-98-8. Molecular formula: [13C]17H14O6. Mole weight: 331.16. | |
| Aflatoxin (BSA) | Aflatoxins belong to the class of mycotoxins. Toxic fungal metabolite and carcinogen. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| aflatoxin B synthase | A heme-thiolate (P-450) enzyme. Isolated from the mold Aspergillus parasiticus. Group: Enzymes. Synonyms: ordA (gene name); 8-O-methylsterigmatocystin,NADPH:O2 oxidoreductase (aflatoxin-B forming). Enzyme Commission Number: EC 1.14.13.175. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0773; aflatoxin B synthase; EC 1.14.13.175; ordA (gene name); 8-O-methylsterigmatocystin,NADPH:O2 oxidoreductase (aflatoxin-B forming). Cat No: EXWM-0773. | |
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