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| Product | Description | |
|---|---|---|
| AFB-Guanine-13C,15N2 | A labelled guanine adduct of Aflatoxin B1. Synonyms: (6aS,8R,9R,9aR)-8-(2-Amino-1,6-dihydro-6-oxo-7H-purin-7-yl)-2,3,6a,8,9,9a-hexahydro-9-hydroxy-4-methoxy-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione-13C,15N2. Molecular formula: C21[13C]H17N3[15N]2O8. Mole weight: 482.38. |  |
| AFB-Guanine Acetic Acid Salt | Acetic acid of a guanine adduct of Aflatoxin B1. Synonyms: (6aS,8R,9R,9aR)-8-(2-Amino-1,6-dihydro-6-oxo-7H-purin-7-yl)-2,3,6a,8,9,9a-hexahydro-9-hydroxy-4-methoxy-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione Acetic Acid. Grade: 95%. Molecular formula: C24H21N5O10. Mole weight: 539.45. | |
| AF-DX 116 | AF-DX 116 has been found to be a selective mAChR M2 antagonist. Synonyms: Otenzepad; AF-DX 116; AF-DX-116; AF-DX116; 11-[[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one. Grade: ≥98% by HPLC. CAS No. 102394-31-0. Molecular formula: C24H31N5O2. Mole weight: 421.54. | |
| AF-DX 116 (Muscarinic Receptor (mAChR) M2 Antagonist, AF-DX 116, Otenzepad, AF-DX116, AF-DX-116, AFDX116) | Selective presynaptic muscarinic receptor M2 antagonist with cardioselectivity. Exhibits antiarrhythmic effects in vivo, also shown to reverse the memory impairment effect of insulin in a mouse model. Group: Biochemicals. Grades: Highly Purified. CAS No. 102394-31-0. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. |  Worldwide |
| AF-DX 384 | AF-DX 384 has been found to be a mAChR M2/M4 selective antagonist. Uses: Parasympatholytics. Synonyms: N-[2-[2-[(Dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide. Grade: ≥98% by HPLC. CAS No. 118290-26-9. Molecular formula: C27H38N6O2. Mole weight: 478.64. | |
| AF-DX 384 | AF-DX 384. Group: Biochemicals. Grades: Purified. CAS No. 118290-26-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Afegostat D-Tartrate | Afegostat D-Tartrate is a pharmacological chaperone, which specifically and reversibly binds acid-β-glucosidase (GCase) in the endoplasmic reticulum (ER) with high affinity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D-Isofagomine D-Tartrate; Isofagomine D-Tartrate. CAS No. 957230-65-8. Pack Sizes: 1 mg. Product ID: HY-14829E. |  |
| Afe I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (BamHI-digest) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme more than 80% of dna pbr322 fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. AGC↑GCT TCG↓CGA. Activity: 10000u.a./ml. Appearance: 10 X SE-buffer B, BSA. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned Afe I gene from Alcaligenes faecalis T2774. Pack: 10 mM Tris-HCl (pH 7.6); 50 mM NaCl; 0.1 mM EDTA; 1 mM DTT; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1014EN. |  |
| Afelimomab | Afelimomab is a mouse monoclonal antibody directed against TNFα. Afelimomab has been used in the research of sepsis treatment. Synonyms: MAK-195F; MAK 195F; MAK195F. Grade: 95%. CAS No. 156227-98-4. | |
| AFG206 | AFG206 is the novel first-generation "type II" FLT3 inhibitor. Synonyms: AFG-206; AFG 206. Grade: >98%. CAS No. 630122-37-1. Molecular formula: C20H19N3O2. Mole weight: 333.38. | |
| AFG210 | AFG210 is a novel first-generation "type II" FLT3 inhibitor. Synonyms: AFG 210; AFG-210; 1-(3-(trifluoromethyl)phenyl)-3-(4-(pyridin-4-yloxy)phenyl)urea. Grade: >98%. CAS No. 228400-22-4. Molecular formula: C19H14F3N3O2. Mole weight: 373.33. | |
| Aficamten | Aficamten is a next-generation cardiac myosin inhibitor with IC50 of 1.4 μM, for the treatment of symptomatic obstructive hypertrophic cardiomyopathy. Synonyms: CK 3773274; CK-3773274; CK3773274; CK-274. CAS No. 2364554-48-1. Molecular formula: C18H19N5O2. Mole weight: 337.38. | |
| Aficamten | Aficamten (CK-274) is a potent cardiac myosin inhibitor with an IC50 of 1.4 μM. Aficamten can be used for the research of hypertrophic cardiomyopathy (HCM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CK-274; CK-3773274. CAS No. 2364554-48-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139465. | |
| Afidopyropen | Afidopyropen (ME-5343) is an Afidopyropen targets sucking insects such as whiteflies, aphids, and leafhoppers by acting on the Nanchung (Nan) and Inactive (Iav) encoding gene of insects, and affecting TRPV channel. Afidopyropen can be used for many crops for its degradability[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ME-5343. CAS No. 915972-17-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124449. | |
| Afimetoran | Afimetoran is an orally active toll-like receptor 7 and 8 (TLR7/8) dual antagonist that can be used to study inflammatory and autoimmune diseases. Synonyms: BMS-986256; 1-Piperidineacetamide, 4-[2-(7,8-dimethyl[1,2,4]triazolo[1,5-a]pyridin-6-yl)-3-(1-methylethyl)-1H-indol-5-yl]-; 2-(4-(2-(7,8-Dimethyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-3-isopropyl-1H-indol-5-yl)piperidin-1-yl)acetamide. Grade: ≥98%. CAS No. 2171019-55-7. Molecular formula: C26H32N6O. Mole weight: 444.57. | |
| Afimetoran | Afimetoran (BMS-986256) is an orally active, selective, and highly bioavailable TLR7/8 antagonist. Afimetoran (BMS-986256) can inhibit TLR7/8 activation of the NF-κB pathway and reverse TLR7 mediated resistance to steroid induced apoptosis in plasma cell like dendritic cells (pDCs). Afimetoran (BMS-986256) can be used for research on inflammation and autoimmune diseases (systemic lupus erythematosus)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-986256. CAS No. 2171019-55-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139567. | |
| Afimkibart | Afimkibart (PF-06480605; RVT-3101) is a fully human monoclonal antibody that selectively inhibits trimeric tumor necrosis factor-like ligand 1A (TL1A). Afimkibart neutralizes active trimeric TL1A, blocks TL1A-induced signaling pathways. Afimkibart inhibits NF-κB activation and IFN-γ production. Afimkibart can be used for the research of inflammatory bowel disease[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-06480605; RVT-3101. CAS No. 2911580-96-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P990876. | |
| Afimoxifene | Afimoxifene (4-hydroxytamoxifen) is a selective estrogen receptor modulator which is the active metabolite of tamoxifen. Afimoxifene is a transdermal gel formulation and is being developed by Ascend Therapeutics, Inc. under the trademark TamoGel. Afimoxifene has completed a phase II clinical trial for the treatment of cyclical mastalgia. Uses: Estrogen antagonists. Synonyms: (E/Z)-4-Hydroxytamoxifen; 4-[1-[4-[2-(Dimethylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol; TamoGel; Phenol, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-. Grade: ≥95%. CAS No. 68392-35-8. Molecular formula: C26H29NO2. Mole weight: 387.51. | |
| Afizagabar | Afizagabar (S44819) is a first-in-class, competitive, and selective antagonist at the GABA-binding site of the α5-GABAAR, with an IC50 of 585 nM for α5β2γ2 and a Ki of 66 nM for α5β3γ2. Afizagabar enhances hippocampal synaptic plasticity and exhibits pro-cognitive efficacy[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S44819; Egis-13529. CAS No. 1398496-82-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120051. | |
| Aflastatin A | It is produced by the strain of Streptomyces sp. MRI 142. Aflatoxin A has anti-Gram-positive bacteria, Pyricularia oryzae and yeast activity (MIC is 0.19-0.39 μg/mL), and inhibits the growth of adenocarcinoma 755 (1.0 mg/kg reduces tumor growth by 75% the above). Synonyms: 2,4-Pyrrolidinedione, 1,5-dimethyl-3-(1,8,9,11,13,15,17,19,21,23,25,27,28,29,30,31-hexadecahydroxy-2,4,6,10,12,14,18,20-octamethyl-32-(tetrahydro-3,4,5,6-tetrahydroxy-6-(2-hydroxyundecyl)-2H-pyran-2-yl)-2-dotriacontenylidene)-; LS-137668. Grade: ≥ 95%. CAS No. 179729-59-0. Molecular formula: C62H115NO24. Mole weight: 1258.56. | |
| Aflatoxicol | The 2 ppm acetonitrile solution of aflatoxicol, a metabolite of aflatoxin, could be commonly used as a standard solution. Uses: Only to be used as a reference standard in analytical laboratories. Synonyms: Aflatoxin Ro; (1S-(1alpha,6abeta,9abeta))-2,3,6a,9a-Tetrahydro-1-hydroxy-4-methoxycyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-11(1H)-one; Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-11(1H)-one, 2,3,6a,9a-tetrahydro-1-hydroxy-4-methoxy-, (1S,6aR,9aS)-; AFL. Grade: ≥98%. CAS No. 29611-03-8. Molecular formula: C17H14O6. Mole weight: 314.29. | |
| Aflatoxin B1-[13C17] | Aflatoxin B1-[13C17] is the labelled analogue of Aflatoxin B1, which is an aflatoxin produced by Aspergillus flavus and A. parasiticus. Synonyms: Aflatoxin B1-13C17. Grade: 95% atom 13C. CAS No. 1217449-45-0. Molecular formula: [13C]17H12O6. Mole weight: 329.15. | |
| Aflatoxin B1-13C-d3 | Aflatoxin B1 labelled standard. Synonyms: (6aR,9aS)-2,3,6a,9a-Tetrahydro-4-(methoxy)-1H,11H-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione-13C,d3; (-)-Aflatoxin B1-13C,d3. Grade: > 95%. Molecular formula: C17H9O6D3. Mole weight: 316.29. | |
| Aflatoxin B1 aldehyde reductase member 2 from Human, Recombinant | Aflatoxin B1 aldehyde reductase member 2 catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Has NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). Can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro). Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. Group: Enzymes. Synonyms: AFB1 aldehyde reductase 1; AFB1-AR 1; Aldoketoreductase 7; Succinic semialdehyde reductase. Enzyme Commission Number: EC 1.1.1.n11. AKR7A2. Mole weight: 39588.9 Da. Source: Human. AFB1 aldehyde reductase 1; AFB1-AR 1; Aldoketoreductase 7; Succinic semialdehyde reductase; EC 1.1.1.n11; AKR7A2; Aflatoxin B1 aldehyde reductase member 2. Cat No: NATE-1196. | |
| Aflatoxin B2 | Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects. Group: Biochemicals. Alternative Names: (6aR, 9aS) -2, 3, 6a, 8, 9, 9a-Hexahydro-4-methoxycyclopenta [c]furo [3, 2: 4, 5]furo [2, 3-h] [1]benzopyran-1, 11-dione; Dihydroaflatoxin B1; Dihydroaflatoxine B1. Grades: Highly Purified. CAS No. 7220-81-7. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| Aflatoxin B2-[13C17] | Aflatoxin B2-[13C17] is the labelled analogue of Aflatoxin B2, which is a mycotoxin found in A. terricola. Synonyms: Aflatoxin B2-13C17; (3S,7R)-11-methoxy-6,8,19-trioxapentacyclo[10.7.0.02,9.03,7.013,17]nonadeca-1,9,11,13(17)-tetraene-16,18-dione-13C17; Dihydroaflatoxine B1-13C17; 2,3,6aR,8,9,9aS-hexahydro-4-methoxy-cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione-13C17; Fully 13C-labelled Aflatoxin B2. Grade: ≥95%. CAS No. 1217470-98-8. Molecular formula: [13C]17H14O6. Mole weight: 331.16. | |
| Aflatoxin (BSA) | Aflatoxins belong to the class of mycotoxins. Toxic fungal metabolite and carcinogen. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| aflatoxin B synthase | A heme-thiolate (P-450) enzyme. Isolated from the mold Aspergillus parasiticus. Group: Enzymes. Synonyms: ordA (gene name); 8-O-methylsterigmatocystin,NADPH:O2 oxidoreductase (aflatoxin-B forming). Enzyme Commission Number: EC 1.14.13.175. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0773; aflatoxin B synthase; EC 1.14.13.175; ordA (gene name); 8-O-methylsterigmatocystin,NADPH:O2 oxidoreductase (aflatoxin-B forming). Cat No: EXWM-0773. | |
| Aflatoxin G1 | Aflatoxin G1 is the major analogue of the green fluorescent family of bisfuranocoumarin mycotoxins produced by Aspergillus flavus and related species. Alfatoxins are one of the most potent mycotoxins known but are in fact "pre-toxins" requiring metabolic activation to the toxic principle. Aflatoxins are found widely in nature in trace amounts particularly grains and nuts. The toxicity of these metabolites was first recognised in the 1950s and their structures elucidated in 1963. Aflatoxins have been extensively reviewed. Source:Aflatoxin G1 from Aspergillus flavus. Group: Biochemicals. Alternative Names: (7aR, 10aS)-3, 4, 7a, 10a-Tetrahydro-5-methoxy-1H, 12H-furo[3, 2:4, 5]furo[2, 3-h]pyrano[3, 4-c][1]benzopyran-1, 12-dione. Grades: Highly Purified. CAS No. 1165-39-5. Pack Sizes: 1mg, 5mg. Molecular Formula: C17H12O7, Molecular Weight: ~328.3. US Biological Life Sciences. | Worldwide |
| Aflatoxin G1 | It is produced by the strain of Aspergillus flavus, Asp. parasiticus. The compound of aflatoxin has the activity of anti-gram-positive bacteria, inhibits cell mitosis, has the effect of liver necrosis and carcinogenesis, and is a mycotoxin which contaminates food. Uses: Only to be used as a reference standard in analytical laboratories. Synonyms: AF G1; (7aR,cis)3,4,7a,10a-tetrahydro-5-methoxy-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]chromene-1,12-dione; Aflatoxin G(1); AFLATOXIN G; Aflatoxin G1,Crystalline; 5-(methyloxy)-3,4,7a,10a-tetrahydro-1H,12H-furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c]chromene-1,12-dione; 1H,12H-Furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione, 3,4,7a,10a-tetrahydro-5-methoxy-, (7aR-cis)-; HSDB 3411; CCRIS 14; HSDB 3455. Grade: ≥98%. CAS No. 1165-39-5. Molecular formula: C17H12O7. Mole weight: 328.27. | |
| Aflatoxin G1-[13C17] | Aflatoxin G1-[13C17] is a labelled Aflatoxin G1, a mycotoxin produced by Aspergillus flavus. Synonyms: Aflatoxin G1-13C17; Fully 13C-labelled Aflatoxin G1. Grade: 95%. CAS No. 1217444-07-9. Molecular formula: [13C]17H12O7. Mole weight: 345.15. | |
| Aflatoxin G2 | Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins are a group of very carcinogenic mycotoxins with hepatotoxic effects. Group: Biochemicals. Alternative Names: (7aR, 10aS)-3, 4, 7a, 9, 10, 10a-Hexahydro-5-methoxy-1H, 12H-furo[3', 2':4, 5]furo[2, 3-h]pyrano[3, 4-c][1]benzopyran-1, 12-dione. Grades: Highly Purified. CAS No. 7241-98-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Aflatoxin G2 | Aflatoxin G2 is a naturally occuring mycotoxin produced by various species of the mold Aspergillus, which can be found in legumes, corn, soybeans, rice, milk, and cheese. Synonyms: Dihydroaflatoxin G1; 5-Methoxy-3,4,7a,9,10,10a-hexahydro-1H,12H-furo[3',2':4,5]furo[2,3-H]pyrano[3,4-c]chromene-1,12-dione. Grade: >98%. CAS No. 7241-98-7. Molecular formula: C17H14O7. Mole weight: 330.29. | |
| Aflatoxin G2-[13C17] | Aflatoxin G2-[13C17] is the labelled analogue of Aflatoxin G2, which is a mycotoxin found in Aspergillus. Synonyms: Aflatoxin G2-13C17; (3S,7R)-11-methoxy-6,8,16,20-tetraoxapentacyclo[10.8.0.02,9.03,7.013,18]icosa-1,9,11,13(18)-tetraene-17,19-dione-13C17; Dihydroaflatoxin G1-13C17; Fully 13C-labelled Aflatoxin G2. Grade: ≥95%. CAS No. 1217462-49-1. Molecular formula: [13C]17H14O7. Mole weight: 347.16. | |
| Aflatoxin M1 | It is produced by the strain of Aspergillus flavus, Asp. parasiticus. The compound of aflatoxin has the activity of anti-gram-positive bacteria, inhibits cell mitosis, has the effect of liver necrosis and carcinogenesis, and is a mycotoxin which contaminates food. Synonyms: AFLATOXIN M1; 4-Hydroxyaflatoxin B1; 3020O28I3; CCRIS 15; (6aR,9aR)-9a-hydroxy-4-methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione; (6aR-cis)-2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxycyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione; CHEBI:78576; Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione,2,3,6a,9a-tetrahydro-9a-hydroxy-4-methoxy-,(6ar,9ar)-. Grade: ≥95%. CAS No. 6795-23-9. Molecular formula: C17H12O7. Mole weight: 328.27. | |
| Aflatoxin M1 | An Aspergillus flavus metabolite. Aflatoxin M1 in milk as a secondary metabolite of the Aflatoxin B1 formed in moldy forages. It is cancerogenic, hepatotoxic, and immunosuppressive in animals and man. Group: Biochemicals. Alternative Names: (6aR, 9aR)-2, 3, 6a, 9a-Tetrahydro-9a-hydroxy-4-methoxy-cyclopenta[c]furo[3, 2:4, 5]furo[2, 3-h][1]benzopyran-1, 11-dione; AFM1. Grades: Highly Purified. CAS No. 6795-23-9. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
| Aflatoxin Q1 | Aflatoxin Q1 is a metabolite of Aflatoxin B1. It is created in human body as a in-vivo detoxification process of Aflatoxin B1. Uses: A metabolite of aflatoxin b1; a hepatocarcinogen in many animal models and probably a human carcinogen. it is produced by the predominant forms of cytochrome p 450 enzymes responsible for the biotransformation of afb1. it shows potential predictive value. Synonyms: Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-3-hydroxy-4-methoxy-, (3S,6aR,9aS)-; Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-3-hydroxy-4-methoxy-, (3S-(3-alpha,6a-alpha,9a-alpha))-; (3S,6aR,9aS)-3-hydroxy-4-methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene-1,11-dione. Grade: ≥98%. CAS No. 52819-96-2. Molecular formula: C17H12O7. Mole weight: 328.27. | |
| Aflatrem | Aflatrem is the secondary metabolite of Aspergillus flavus. It is able to induce degeneration of neuronal processes in hippocampal neurotransmitter systems at low dose. It potentiates the gamma-aminobutyric acid (GABA)-induced chloride current. It is a tremorgenic mycotoxin with acute neurotoxic effect. Synonyms: 4H-3,15a-Epoxy-1-benzoxepino[6',7':6,7]indeno[1,2-b]indol-4-one, 9-(1,1-dimethyl-2-propenyl)-2,3,5b,6,7,7a,8,13,13b,13c,14,15-dodecahydro-5b-hydroxy-2,2,13b,13c-tetramethyl-, (3R,5bS,7aS,13bS,13cR,15aS)-; 9-(1,1-Dimethyl-2-propenyl)-2,3,5b,6,7,7aα,8,13,13b,13c,14,15-dodecahydro-5bβ-hydroxy-2,2,13bβ,13cα-tetramethyl-4H-3β,15aβ-epoxy-1-benzoxepino[6',7':6,7]indeno[1,2-b]indol-4-one; α,α-dimethylallylpaspalinine. Grade: 98.0%. CAS No. 70553-75-2. Molecular formula: C32H39NO4. Mole weight: 501.66. | |
| Aflavarin | Aflavarin is a metabolite of the Sclerotia of Aspergillus flavus displaying anti-insectan activity against the fungivorous beetle Carpopbilus bemipterus. Synonyms: (3,8'-Bi-2H-1-benzopyran)-2,2'-dione, 5-(hydroxymethyl)-4,4',7,7'-tetramethoxy-5'-methyl-, (-)-; (-)-5-(Hydroxymethyl)-4,4',7,7'-tetramethoxy-5'-methyl[3,8'-bi-2H-1-benzopyran]-2,2'-dione. Grade: 98.0%. CAS No. 144429-67-4. Molecular formula: C24H22O9. Mole weight: 454.43. | |
| Aflavazole | Aflavazole is a metabolite of the sclerotia of Aspergillus flavus. It shows antifeedant activity against the fungivorous beetle Carpophilus hemipterus remarkably. Synonyms: (1R,4S,4aS,13dS,14R,16R,16aS)-1,2,3,4,5,6,9,13d,14,15,16,16a-Dodecahydro-1,7,14,16a-tetramethylphenanthro[2,1-c]carbazole-4,16-diol; (+)-Aflavazole; Benzo(4a,5)naphtho(2,1-c)carbazole-4,16-diol, 1,2,3,4,5,6,9,13d,14,15,16,16a-dodecahydro-1,7,14,16a-tetramethyl-, (1alpha,4alpha,4aS*,13dbeta,14alpha,16beta,16aalpha)-(+)-; Benzo(4a,5)naphtho(2,1-c)carbazole-4,16-diol,1,2,3,4,5,6,9,13d,14,15,16,16a-dodecahydro-1,7,16a-tetramethyl-, (1R,4S,4aS,13dS,14R,16R,16aS)-rel-(+)-. Grade: 97.5%. CAS No. 2043963-70-6. Molecular formula: C28H35NO2. Mole weight: 417.58. | |
| Aflibercept | Aflibercept is a recombinant fusion protein and acts as a VEGF inhibitor. Aflibercept is used for the treatment of wet macular degeneration and metastatic colorectal cancer. Synonyms: Eylea. CAS No. 862111-32-8. Molecular formula: C4318H6788N1164O1304S32. Mole weight: 96898.57. | |
| Aflibercept | Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR1 and VEGFR2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: VEGF Trap; VEGF-TRAPR1R2; VEGF-trapR1. CAS No. 862111-32-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-108801. | |
| Aflibercept (VEGF Trap) | Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR1 and VEGFR2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 862111-32-8. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-108801A. | |
| Afloqualone | Afloqualone (HQ-495) is a quinazolinone family GABAergic drug that acts as an agonist of the β subtype of the GABAa receptor, exhibiting sedative and muscle-relaxant effects. Category: Active pharmaceutical ingredients. CAS No. 56287-74-2. Product ID: API56287742. Molecular formula: C16H14FN3O. Mole weight: 283.3. |  |
| Afloqualone | Afloqualone (HQ-495) is an orally active central muscle relaxant and antivertiginous agent that can increase the sensitivity of GABA receptors in neurons of the lateral vestibular nucleus. Afloqualone (HQ-495) can be used in the research of low back pain and neck-arm-shoulder syndrome[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HQ-495. CAS No. 56287-74-2. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-B1833. | |
| Afloqualone Impurity 1 | Afloqualone Impurity 1. Uses: For analytical and research use. CAS No. 136426-54-5. Molecular formula: C16H8Cl2FN5O. Mole weight: 376.17. Catalog: APB136426545. |  |
| a-Fluoro-b-alanine | a-Fluoro-b-alanine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| a-Fluoro-b-alanine-13C3 ((2R)-3-Amino-2-fluoropropanoic Acid-13C3) | A stable isotope analogue of the catabolism of the anti-cancer drug 5-Flurouracil. Group: Biochemicals. Alternative Names: (2R)-3-Amino-2-fluoropropanoic Acid-13C3. Grades: Highly Purified. CAS No. 1246819-54-4. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| AFM32a hydrochloride | AFM32a (PAD2-IN-1) hydrochloride, a benzimidazole-based derivative, is a potent and selective protein arginine deiminase 2 (PAD2) inhibitor. AFM32a hydrochloride shows superior selectivity for PAD2 over PAD4 (95-fold) and PAD3 (79-fold)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PAD2-IN-1 hydrochloride. CAS No. 2988594-85-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-136557A. | |
| a-Fmoc-L-Lys((+)-Biotinyl-e-aminocaproyl)-OH 99+% | a-Fmoc-L-Lys((+)-Biotinyl-e-aminocaproyl)-OH 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| AFM Probe from SWCNT or MWCNT Tip angle from ± 3° to ± 20 ° available | AFM Probe from SWCNT or MWCNT Tip angle from ± 3° to ± 20 ° available. |  |
| AFN-1252 | AFN-1252 is an enoyl-(acyl-carrier protein) reductase fabl inhibitor, inhibited all clinical isolates of Staphylococcus aureus and Staphylococcus epidermidis at concentrations of ≤0.12 μg/ml. Uses: Antibacterial. Synonyms: AFN-1252; AFN 1252; AFN1252; AFN-12520000; API-1252; Debio-1452; AFN12520000; API1252; Debio1452. (E)-N-methyl-N-[(3-methyl-1-benzofuran-2-yl)methyl]-3-(7-oxo-6,8-dihydro-5H-1,8-naphthyridin-3-yl)prop-2-enamide. Grade: ≥95%. CAS No. 620175-39-5. Molecular formula: C22H21N3O3. Mole weight: 375.43. | |
| Afobazole | Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety. Experiments of mice have showed antimutagenic and antiteratogenic properties. Synonyms: CM346; Afobazol; Fabomotizole; CM 346; CM-346. Grade: >98%. CAS No. 173352-21-1. Molecular formula: C15H21N3O2S. Mole weight: 307.41. | |
| Afobazole hydrochloride | Fabomotizole (brand name Afobazole) is an anxiolytic drug launched in Russia in the early 2000s. It produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions. Its mechanism of action remains poorly defined however, with GABAergic, NGF- and BDNF-release-promoting, MT1 receptor agonism, MT3 receptor antagonism, and sigma agonism suggested as potential mechanisms. Fabomotizole was shown to inhibit MAO-A reversibly and there might be also some involvement with serotonin receptors. Clinical trials have shown fabomotizole to be well tolerated and reasonably effective for the treatment of anxiety. Experiments of mice have showed antimutagenic and antiteratogenic properties. Synonyms: CM346 hydrochloride; Afobazol hydrochloride; Fabomotizole hydrochloride; CM 346 hydrochloride; CM-346 hydrochloride. Grade: >98%. CAS No. 173352-39-1. Molecular formula: C15H22ClN3O2S. Mole weight: 343.87. | |
| Afoxolaner | Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect γ-aminobutyric acid receptor (GABA) and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1093861-60-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16974. | |
| Afoxolaner | Afoxolaner is an insecticide and acaricide used in dogs to treat and prevent flea infestations. Used to treat specifically the Sarcoptes scabiei var. canis species. Group: Biochemicals. Grades: Highly Purified. CAS No. 1093861-60-9. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C26H17ClF9N3O3, Molecular Weight: 625.87. US Biological Life Sciences. | Worldwide |
| afoxolaner Impurity 1 | afoxolaner Impurity 1. Uses: For analytical and research use. Molecular formula: C26H19ClF9N3O4. Mole weight: 643.89. Catalog: APB12362. | |
| afoxolaner Impurity 2 | afoxolaner Impurity 2. Uses: For analytical and research use. Molecular formula: C26H15ClF9N3O2. Mole weight: 607.86. Catalog: APB12363. | |
| afoxolaner Impurity 3 | afoxolaner Impurity 3. Uses: For analytical and research use. Molecular formula: C26H18ClF9N2O4. Mole weight: 628.88. Catalog: APB12364. | |
| afoxolaner Impurity 4 | afoxolaner Impurity 4. Uses: For analytical and research use. Molecular formula: C24H15ClF6N2O4. Mole weight: 544.83. Catalog: APB12365. | |
| afoxolaner Impurity 5 | afoxolaner Impurity 5. Uses: For analytical and research use. CAS No. 1308362-48-2. Molecular formula: C22H12ClF6NO3. Mole weight: 487.78. Catalog: APB1308362482. | |
| Afoxolaner (Standard) | Afoxolaner (Standard) is the analytical standard of Afoxolaner. This product is intended for research and analytical applications. Afoxolaner is an orally active isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect γ-aminobutyric acid receptor (GABA) and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1093861-60-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16974R. | |
| AFP 07 | AFP 07 is a 7,7-difluoroprostacyclin derivative that acts as a selective and highly potent agonist for the IP receptor. Synonyms: (5Z)-5-[(3aR,4R,5R,6aS)-3,3-difluoro-5-hydroxy-4-[(E,3S,4S)-3-hydroxy-4-methylnon-1-en-6-ynyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[b]furan-2-ylidene]pentanoic acid. Grade: ≥98%. CAS No. 788799-13-3. Molecular formula: C22H30F2O5. Mole weight: 412.5. | |
| AFP-464 | AFP-464 is a synthetic lysyl prodrug of the amino-substituted flavone derivate aminoflavone with antiproliferative and antineoplastic activities. AFP464 is rapidly converted to aminoflavone in plasma. Aminoflavone activates the aryl hydrocarbon receptor (AhR) signaling pathway leading to an increase in cytochrome P450 1A1 (CYP1A1) and cytochrome P450 1A2 (CYP1A2) expression and, to a lesser extent, an increase in cytochrome P450 1B1 (CYP1B1) expression. Synonyms: AFP464; AFP 464; Hexanamide, 2,6-diamino-N-(4-(5-amino-6,8-difluoro-7-methyl-4-oxo-4H-1-benzopyran-2-yl)-2-fluorophenyl)-, (2S)-. CAS No. 468719-52-0. Molecular formula: C23H27F3N4O6S. Mole weight: 448.44. | |
| Afragilimycin A | It is produced by the strain of Streptomyces neohygroscopicus sub-sp, afragilimycetius 19255. It has anti-gram-positive bacteria and anti-gram-negative bacteria including anaerobic bacteria activity. Synonyms: Afrigilimycin A; (2S)-4-[(2E,4E,6R)-6-[(1S,2S,3R,5S,6R)-2,5-dimethylspiro[4,9-dioxabicyclo[3.3.1]non-7-ene-6,2'-oxirane]-3-yl]-4-methylhepta-2,4-dienoyl]-1-[(5S,6S)-5-hydroxy-6-methyloxan-2-yl]-2-[(2S)-1-(methylamino)-1-oxopropan-2-yl]-3-oxo-2H-pyrrol-5-olate. CAS No. 76559-69-8. Molecular formula: C32H43N2O9-. Mole weight: 599.69. | |
| African Mango Seed Extract | African Mango Seed Extract. Applications: Used for health care products, dietary supplements, weight loss, reducing blood lipids. Group: Others. Synonyms: African Mango Seed Extract; 9005-80-5; Irvingia GabonensisSeed. CAS No. 9005-80-5. Purity: 20% Phytoprotein By KJELDAHL, 10:1 By TLC. Appearance: Light yellow fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Seed. Species: Irvingia GabonensisSeed. African Mango Seed Extract; 9005-80-5; Irvingia GabonensisSeed; plant extract. Pack: 20KG-25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-103. | |
| African Mango Seed P.E. 10:1 | African Mango Seed P.E. 10:1 (Irvingia Gabonensis). |  CA, FL & NJ |
| Aftin-4 | Aftin-4 is an Amyloid-β42 (Aβ42) inducer. Uses: Scientific research. Category: Signaling pathways. CAS No. 866893-90-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111267. | |
| Aftin-4 (N6-Methyl-(R)-roscovitine, Amyloid-beta Forty-Two Inducer 4) | Roscovitine-related purine with no activity on CDKs (used as control for roscovitine). Selectively and potently increases production of extracellular Abeta42 and decreases production of extracellular Abeta38 in cultured cells. Extracellular Abeta40 levels remain stable. Intracellular levels of these amyloids appear to remain stable. Alzheimer's Disease (AD) accelerator that interacts with VDAC1, prohibitin and mitofilin, possibly interfering with subcellular compartmentalization and lipid rafts properties, shifting gamma-secretase activity toward Abeta42 generation. Induces a reversible mitochondrial phenotype reminiscent of the one observed in AD brains. Tool to detect inhibitors of Aftin-induced actions (potential anti-AD compounds). Binds pyridoxal kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 866893-90-5. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| Aftin-5 | Aftin-5 is an inducer for Amyloid-β 42 (Aβ42). Aftin-5 upregulates Aβ42 and downregulates Aβ38 levels in a β-secretase- and γ-secretase-dependent manner by altering the ultrastructure of mitochondria. Aftin-5 exhibits slightly cytotoxicity in cell SH-SY5Y, HT22, N2a and N2a-AβPP695, with IC50s of 180, 194, 178 and 150 μM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1461717-05-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136674. | |
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