A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
AK-7 is a selective cell- and brain-permeable SIRT2 inhibitor, with an IC50 of 15.5 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 420831-40-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16691.
AkaLumine hydrochloride
AkaLumine hydrochloride is a D-luciferin (HY-12591A) analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. AkaLumine hydrochloride emits near-infrared (NIR) light (λmax=677?nm) in reactions with native Fluc. AkaLumine hydrochloride has high tissue-penetration and increases detection sensitivity from deep-tissue targets[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2558205-28-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112641A.
Akardite II
Akardite II (AK-II) is a stabilizer for nitrocellulose (NC) propellants as it scavenges NOx. Akardite II helps control a variety of plant pathogens and weeds, which can be used as fungicides and herbicides[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AK-II. CAS No. 13114-72-2. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W004643.
Akardit II
Akardit II. Group: Biochemicals. Grades: Highly Purified. CAS No. 13114-72-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
Worldwide
Akarkara P.E. 10:1 (Anacyclus Pyrethrum)
Akarkara P.E. 10:1 (Anacyclus Pyrethrum).
CA, FL & NJ
AKB48 N-Pentanoic Acid
AKB48 N-Pentanoic Acid. Group: Biochemicals. Alternative Names: APINACA N-Pentanoic Acid; 5-(3-((3s,5s,7s)-Adamantan-1-ylcarbamoyl)-1H-indazol-1-yl)pentanoic Acid. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C23H29N3O3, Molecular Weight: 395.49. US Biological Life Sciences.
Worldwide
AKB-6899
AKB-6899, a prolyl hydroxylase domain 3 (PHD3) inhibitor, is a selective HIF-2α stabilizer. AKB-6899 also increases soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages, and has antitumor and antiangiogenic effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1007377-55-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113649.
a-Ketoglutaric acid disodium salt
a-Ketoglutaric acid disodium salt. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100g, 250g, 25g, 1Kg, 5Kg. US Biological Life Sciences.
Worldwide
a-Ketoglutaric Acid Disodium Salt Dihydrate
a-Ketoglutaric Acid Disodium Salt Dihydrate. Group: Biochemicals. Alternative Names: 2-Oxoglutaric acid disodium salt; Disodium 2-ketoglutarate. Grades: Highly Purified. CAS No. 305-72-6. Pack Sizes: 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C5H4Na2O5·2H2O, Molecular Weight: 226.09. US Biological Life Sciences.
Worldwide
a-Ketoglutaric acid disodium salt dihydrate 99+%
a-Ketoglutaric acid disodium salt dihydrate 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg, 5Kg. US Biological Life Sciences.
Worldwide
a-Ketoglutaric acid potassium salt
a-Ketoglutaric acid potassium salt. Group: Biochemicals. Alternative Names: 2-Oxopentanedioic acid potassium salt; Potassium hydrogen 2-ketoglutarate. Grades: Highly Purified. CAS No. 997-43-3. Pack Sizes: 25g, 50g, 100g. Molecular Formula: C?H?O?K, Molecular Weight: 184.19. US Biological Life Sciences.
Worldwide
AKI-001
AKI-001 is a potent Aurora kinase inhibitor, which exhibits low nanomolar potency against both Aurora A and Aurora B enzymes, excellent cellular potency (IC50 < 100 nM), and good oral bioavailability. Synonyms: AKI-001; AKI 001; AKI001. Grade:>98%. CAS No. 925218-37-7. Molecular formula: C21H24N4O. Mole weight: 348.45.
AKI603
AKI603 is an inhibitor of Aurora kinase A (AurA) with IC50 of 12.3 nM. It can induce senescence in chronic myeloid leukemia cells carrying the T315I mutation. AKI603 shows strong anti-proliferative activity in leukemia cells. Synonyms: AKI-603. Grade: 98%. CAS No. 1432515-73-5. Molecular formula: C19H23N9O2. Mole weight: 409.4.
A-kinase anchor protein 9 (1398-1407)
A-kinase anchor protein 9 (1398-1407) is amino acids 1398 to 1407 fragment of A-kinase anchor protein 9. AKAP-9 is a scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. Synonyms: AKAP-9 (1398-1407).
aklanonic acid methyl ester cyclase
The enzyme is involved in the biosynthesis of aklaviketone, an intermediate in the biosynthetic pathways leading to formation of several anthracycline antibiotics, including aclacinomycin, daunorubicin and doxorubicin. Group: Enzymes. Synonyms: dauD (gene name); aknH (gene name); dnrD (gene name); methyl aklanonate cyclase; methyl aklanonate-aklaviketone isomerase (cyclizing); aklaviketone lyase (decyclizing). Enzyme Commission Number: EC 5.5.1.23. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5624; aklanonic acid methyl ester cyclase; EC 5.5.1.23; dauD (gene name); aknH (gene name); dnrD (gene name); methyl aklanonate cyclase; methyl aklanonate-aklaviketone isomerase (cyclizing); aklaviketone lyase (decyclizing). Cat No: EXWM-5624.
aklanonic acid methyltransferase
The enzyme from the Gram-positive bacterium Streptomyces sp. C5 is involved in the biosynthesis of the anthracycline daunorubicin. Group: Enzymes. Synonyms: DauC; AAMT. Enzyme Commission Number: EC 2.1.1.288. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1895; aklanonic acid methyltransferase; EC 2.1.1.288; DauC; AAMT. Cat No: EXWM-1895.
aklaviketone reductase
The enzyme is involved in the synthesis of the aklavinone aglycone, a common precursor for several anthracycline antibiotics including aclacinomycins, daunorubicin and doxorubicin. The enzyme from the Gram-negative bacterium Streptomyces sp. C5 produces daunomycin. Group: Enzymes. Synonyms: dauE (gene name); aknU (gene name). Enzyme Commission Number: EC 1.1.1.362. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0279; aklaviketone reductase; EC 1.1.1.362; dauE (gene name); aknU (gene name). Cat No: EXWM-0279.
Aklavin
It is produced by the strain of Streptomyces galilaeus. It has the activity of resisting gram positive bacterium, negative bacterium, candida and ringworm. Synonyms: Aclacinomycin T; 1-Deoxypyrromycin; Aclacinomycin; Doxypyrromycin; NSC 100290; CHEBI:74351; 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexapyranosyl)oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-; aklavine. CAS No. 60504-57-6. Molecular formula: C30H35NO10. Mole weight: 569.60.
Aklavinone
Aklavinone is an anthracycline drug with an antitumor effect. CAS No. 16234-96-1. Molecular formula: C22H20O8. Mole weight: 412.39.
aklavinone 12-hydroxylase
The enzymes from the Gram-positive bacteria Streptomyces peucetius and Streptomyces purpurascens participate in the biosynthesis of daunorubicin, doxorubicin and rhodomycins. The enzyme from Streptomyces purpurascens is an FAD monooxygenase. Group: Enzymes. Synonyms: DnrF; RdmE; aklavinone 11-hydroxylase (incorrect). Enzyme Commission Number: EC 1.14.13.180. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0779; aklavinone 12-hydroxylase; EC 1.14.13.180; DnrF; RdmE; aklavinone 11-hydroxylase (incorrect). Cat No: EXWM-0779.
aklavinone 7-L-rhodosaminyltransferase
Isolated from the bacterium Streptomyces galilaeus. Forms a complex with its accessory protein AknT, and has very low activity in its absence. The enzyme can also use dTDP-2-deoxy-β-L-fucose. Involved in the biosynthesis of other aclacinomycins. Group: Enzymes. Synonyms: AknS/AknT; aklavinone 7-β-L-rhodosaminyltransferase; dTDP-β-L-rhodosamine:aklavinone 7-α-L-rhodosaminyltransferase. Enzyme Commission Number: EC 2.4.1.326. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2563; aklavinone 7-L-rhodosaminyltransferase; EC 2.4.1.326; AknS/AknT; aklavinone 7-β-L-rhodosaminyltransferase; dTDP-β-L-rhodosamine:aklavinone 7-α-L-rhodosaminyltransferase. Cat No: EXWM-2563.
Aklomide
Aklomide is antiprotozoal agent against coccidiosis. Synonyms: 2-chloro-4-nitrobenzamide 2-Chloro-4-nitrobenzamide aklomide 3011-89-0 Aklomix Clomide Alkomide Benzamide, 2-chloro-4-nitro- component of Aklomix component of Novastat-W. CAS No. 3011-89-0. Molecular formula: C7H5ClN2O3. Mole weight: 200.58.
AKN-028
AKN-028, the FLT3/KIT kinase inhibitor, is an orally bioavailable protein tyrosine kinase inhibitor for FMS-related tyrosine kinase 3 (FLT3; STK1) and stem cell factor receptor (SCFR; KIT), with potential antineoplastic activity. FLT3/KIT kinase inhibitor AKN-028 binds to and inhibits both the wild-type and mutated forms of FLT3 and SCFR. This may result in an inhibition of tumor cell proliferation in cancer cell types that overexpress these receptor tyrosine kinases. Synonyms: AKN 028; AKN028; N2-(1H-Indol-5-yl)-6-(pyridin-4-yl)pyrazine-2,3-diamine; 2,3-Pyrazinediamine, N3-1H-indol-5-yl-5-(4-pyridinyl)-; N3-(1H-Indol-5-yl)-5-(4-pyridinyl)-2,3-pyrazinediamine. Grade: ≥95%. CAS No. 1175017-90-9. Molecular formula: C17H14N6. Mole weight: 302.33.
AKOS B018304
AKOS B018304 is a potent inhibitor of chikungunya virus with low micromolar activity. Synonyms: (E)-2-Mercapto-5-(2-Nitrobenzylidene)Thiazol-4(5H)-One; O-Nitrobenzalrhodanin. Grade: 98%. CAS No. 6308-22-1. Molecular formula: C10H6N2O3S2. Mole weight: 266.3.
AKR1B10-IN-1
AKR1B10-IN-1 is a potent inhibitor of AKR1B10 (Aldo-Keto Reductase 1B10) with an IC50 of 3.5 nM. AKR1B10-IN-1 suppresses proliferation, metastasis, and Cisplatin (CDDP) resistance of lung cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2136579-33-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139696.
A cell-permeable 3-phenyl-aminobenzoate compound that acts as a potent, competitive, reversible, active-site targeting inhibitor of aldo-keto reductase 1C3 (AKR1C3; type 5 17b-hydroxysteroid dehydrogenase) (IC50 = 60nM) with excellent selectivity over other closely related human AKR isoforms (IC50 = 22.7, 15.4, 62.7, >50, and >50uM for and AKR1C1, AKR1C2, AKR1C4, AKR1B1 and AKR1B10, respectively. Exhibits a weak inhibitory effect on cyclooxygenase 1 and 2 (IC50 = 100uM). Shown to efficiently block the AKR1C3-mediated production of testosterone in LNCaP-AKR1C3 cells (~10uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Akrobomycin
It is produced by the strain of Actinomadura reseoviolacea 129-AVI. It has anti-gram-negative bacteria, ringworm and tumor activity. Synonyms: 9,10-Anhydro-13-deoxocarminomycin; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-8-ethyl-9,10-dihydro-1,6,11-trihydroxy-, (S)-; DTXSID601008673; LS-94000; 3-Ethyl-5,10,12-trihydroxy-6,11-dioxo-1,2,6,11-tetrahydrotetracen-1-yl 3-amino-2,3,6-trideoxyhexopyranoside; Akrobomycin; Rubomycin Q1. CAS No. 89156-94-5. Molecular formula: C26H27NO8. Mole weight: 481.49.
Akt1 and Akt2-IN-1
Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 and Akt2 with the IC50 of 3.5 nM and 42 nM respectively. It has potent and balanced activity. It is dependent on the PH-domain for Akt inhibition. It is selective for Akt1/2 over Akt3 and is highly selective over other members of the AGC family of kinases in vitro. It has potent inhibitory activity against Akt1 and Akt 2 in vivo in a mouse lung and efficacy in a tumor xenograft model. It has moderate activity in an hERG binding assay and is a substrate for human P-glycoprotein. It also shows good physical properties with a human plasma protein binding. Uses: Akt1 and akt2-in-1 has potent inhibitory activity against akt1 and akt 2 and efficacy in a tumor xenograft model. Synonyms: Akt Inhibitor 17; Akti_2008; Akti 2008; Akti2008; Akti-2008; Akt Inhibitor 17; Akt-Inhibitor-17; AktInhibitor17; 3-Phenyl-2-[4-[[4-[5-(2-pyridinyl)-1H-1,2,4-triazol-3-yl]-1-piperidinyl]methyl]phenyl]-1,6-Naphthyridin-5(6H)-one; Akti_2008; 3-phenyl-2-[4-[[4-(3-pyridin-2-yl-1H-1,2,4-triazol-5-yl)piperidin-1-yl]methyl]phenyl]-6H-1,6-naphthyridin-5-one. Grade: >98%. CAS No. 893422-47-4. Molecular formula: C33H29N7O. Mole weight: 539.63.
AKT-I-1 is a selective and reversible inhibitor of Akt1. Synonyms: Akt-I-1 compound; AktI 1; N3-(7-Cyclobutyl-3-phenyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-N1,N1,2,2-tetramethyl-1,3-propanediamine. CAS No. 473382-39-7. Molecular formula: C22H30N6. Mole weight: 378.51.
Akt-I-1,2 HCl
Akt-I-1,2 is a selective, non-ATP-competitive Akt1 and Akt2 inhibitor. Synonyms: Akt I 1,2 HCl; AktI1,2 HCl; Benzenemethanamine, alpha,alpha-dimethyl-4-(3-phenyl-2-quinoxalinyl)-, hydrochloride (1:1). CAS No. 473382-50-2. Molecular formula: C23H22ClN3. Mole weight: 375.90.
AKTide-2T
AKTide-2T, a peptide substrate for Akt/PKB, has been found to act as an inhibitor and mimics the optimal phosphorylation sequence of Akt. Synonyms: AKTide-2T; 324029-01-8; ARKRERTYSFGHHA; AKOS024457090; PD079315. Grade: ≥95% by HPLC. CAS No. 324029-01-8. Molecular formula: C74H114N28O20. Mole weight: 1715.89.
AKTide-2T
AKTide-2T. Group: Biochemicals. Grades: Purified. CAS No. 324029-01-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
AKTide-2T TFA
AKTide-2T is a peptide substrate for Akt/PKB. It acts as an inhibitor and mimics the optimal phosphorylation sequence of Akt. Molecular formula: C76H115F3N28O22. Mole weight: 1829.89.
AKT-IN-11
AKT-IN-11 is one of the most effective antibacterial agents against human hepatoma BEL-7402 cell line with an IC50 of 1.15 μM. Synonyms: (7R)-5-chloro-3-((1E,3E)-3,5-dimethylhepta-1,3-dien-1-yl)-7-hydroxy-7-methyl-2-(4-(trifluoromethoxy)benzyl)isoquinoline-6,8(2H,7H)-dione. Molecular formula: C27H27ClF3NO4. Mole weight: 521.96.
AKT-IN-2
AKT-IN-2 is a selective and orally bioavailable AKT inhibitor (IC50 = 5 nM for AKT1). Synonyms: AKT-IN-2; CHEMBL4129379; SCHEMBL1662401; QRULDXBXPXGMQS-QGZVFWFLSA-N; QRULDXBXPXGMQS-QGZVFWFLSA-O; BDBM50271964; AKOS040732404; HY-112148; CS-0043488; (R)-5-methyl-4-(4-(1-(2-(pyrrolidin-1-yl)ethyl)-4-(3,3,3-trifluoropropyl)-1H-imidazol-2-yl)piperidin-1-yl)-5,6-dihydropyrido[2,3-d]pyrimidin-7(8H)-one; 1295514-91-8. CAS No. 1295514-91-8. Molecular formula: C25H34F3N7O. Mole weight: 505.58.
AKT-IN-23
AKT-IN-23 is an AKT inhibitor. AKT-IN-23 can be used in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1226801-23-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161704.
AKT-IN-3
AKT-IN-3 is a potent and orally active low hERG blocking Akt inhibitor, with 1.4 nM, 1.2 nM and 1.7 nM for Akt1, Akt2 and Akt3, respectively. AKT-IN-3 also shows good inhibitory activity against other AGC family kinases, such as PKA, PKC, ROCK1, RSK1, P70S6K, and SGK. Synonyms: 2-Piperidineacetamide, 5-[[[5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)-2-furanyl]carbonyl]amino]-4-(3,4-difluorophenyl)-N-methyl-, (2S,4S,5S)-. CAS No. 2374740-21-1. Molecular formula: C23H23Cl2F2N5O3. Mole weight: 526.36.
AKT-IN-5
AKT-IN-5 is an inhibitor of Akt1 and Akt2 with IC50s of 450 nM and 400 nM, respectively. CAS No. 1402608-05-2. Molecular formula: C23H20N4O2. Mole weight: 384.43.
Akt Inhibitor IV
Akt inhibitor IV is an inhibitor of Akt activation that inhibits Akt-mediated nuclear export of Forkhead box class O transcription factor 1a (FOXO1a; IC50 = 625 nM) and reduces phosphorylation of Akt at Ser473 and Thr308 in a dose-dependent manner. Synonyms: 5-(2-Benzothiazolyl)-3-ethyl-2-[2-(methylphenylamino)ethenyl]-1-phenyl-1H-benzimidazolium iodide. Grade: ≥95%. CAS No. 681281-88-9. Molecular formula: C31H27N4S·I. Mole weight: 614.6.
AKT inhibitor VIII
Akt Inhibitor VIII is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity. It does not exhibit any inhibitory effect against pleckstrin homology (PH) domain-lacking Akts, AGC family kinases, PKA, PKC or SGK. It also prevails over Akt1/Akt2-mediated resistance to chemotherapeutics in tumor cells and has been shown to block basal and stimulated phosphorylation/activation of Akt1/Akt2 in cultured cells and in mice. Synonyms: AKT inhibitor VIII; AKT-inhibitor-VIII; AKT inhibitor-8; AKT-inhibitor-8; Akt-I 1,2; Akti-1/2. Sigma-A6730. 2H-Benzimidazol-2-one, 1,3-dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]-4-piperidinyl]-. Grade: >98%. CAS No. 612847-09-3. Molecular formula: C34H29N7O. Mole weight: 551.64.
AKT inhibitor VIII
AKT inhibitor VIII (AKTi-1/2) is a cell-permeable quinoxaline compound that has been shown to potently, selectively, allosterically, and reversibly inhibit Akt1, Akt2, and Akt3 activity with IC50s of 58 nM, 210 nM, and 2119 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AKTi-1/2. CAS No. 612847-09-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10355.
AKT Kinase Inhibitor
AKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 842148-40-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10249A.
AKT Kinase Inhibitor
AKT Kinase Inhibitor is a Akt Kinase Inhibitor. Synonyms: 2-Propyn-1-ol, 3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-. Grade: >98%. CAS No. 842148-40-7. Molecular formula: C16H19N7O3. Mole weight: 357.37.
AK-toxin I
It is produced by the strain of Alternaria kikuchiana AS-1223. It's a plant toxin (especially for pear trees). Synonyms: CTK3E8898; (2E,4E,6E)-8-(2-acetamido-3-phenyl-butanoyl)oxy-8-(2-methyloxiran-2-yl)octa-2,4,6-trienoic Acid. Grade: 95%. CAS No. 85146-09-4. Molecular formula: C23H27NO6. Mole weight: 413.46.
AK-toxin ll
It is produced by the strain of Alternaria kikuchiana AS-1223. It's a plant toxin (especially for pear trees). Synonyms: L-Phenylalanine, N-acetyl-, 7-carboxy-1-(2-methyloxiranyl)-2,4,6-heptatrienyl ester, (2S-(2R*(1S*,2E,4Z,6E)))-. Grade: 95%. CAS No. 85146-10-7. Molecular formula: C22H25NO6. Mole weight: 399.44.
Akt/SKG Substrate Peptide is a synthetic peptide and used as a substrate for Akt/PKB. It could not be phosphorylated by MAP kinase or p70 S6 kinase activated protein kinase-1. Synonyms: N5-(Diaminomethylene)-L-ornithyl-L-prolyl-N5-(diaminomethylene)-L-ornithyl-L-alanyl-L-alanyl-L-threonyl-L-phenylalanine. CAS No. 276680-69-4. Molecular formula: C36H59N13O9. Mole weight: 817.95.
AKU-005
AKU-005 is a FAAH and MAGL dual inhibitor with IC50 values of 63, 389 nM for rat and human FAAH, respectively. AKU-005 has the potential for the research of trigeminal hyperalgesia[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1515855-85-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163733.
Al0.2CoCrFeNi Alloy Powder
Al0.2CoCrFeNi Alloy Powder.
AL-034
AL-034 is a Toll-like receptor 7 (TLR7) agonist in a phase I clinical trial for the treatment of HBV infections. Uses: The potential treatment of hbv infections. Synonyms: AL-034; AL 034; AL034.
Al0.5CoCrFeNi Alloy Powder
Al0.5CoCrFeNi Alloy Powder.
AL-072
AL072 is an antibiotic against Legionella produced by Strepyomyces sp. AL91. It has strong anti-legionella pneumophila activity. CAS No. 168482-44-8. Molecular formula: C41H76O5. Mole weight: 649.04.
AL 082D06
AL 082D06 is a selective, nonsteroidal glucocorticoid receptor (GR) antagonist with Ki of 210 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: D06; D-06. CAS No. 256925-03-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15709.
AL 082D06
AL 082D06, also called as D-06, is a selective nonsteroidal antagonist of glucocorticoid receptor (GR) (Ki= 210 nM) without significant activity on AR, PR, MR and ER(Ki > 10 uM). AL 082D06 binds competitively with steroids, likely occupying a similar site. Synonyms: AL082D06; AL-082D06; AL 082D06; D-06. CAS No. 256925-03-8. Molecular formula: C23H24ClN3O2. Mole weight: 409.91.
AL-3152 is a aldehyde reductase inhibitors originated by Alcon. But clinical trials was discontinued for the treatment of Diabetic nephropathies, Diabetic neuropathies and Diabetic retinopathy. Uses: Diabetic nephropathies; diabetic neuropathies; diabetic retinopathy. Synonyms: AL-3152; AL 3152; AL3152; 2,7-difluoro-4-methoxy-Spiro(9H-fluorene-9,4'-imidazolidine)-2',5'-dione. Grade: 98%. CAS No. 126048-33-7. Molecular formula: C16H10F2N2O3. Mole weight: 316.62.
AL-321
AL-321 is a bio-active chemical, but no detailed information has been published yet. Synonyms: AL-321; AL321; AL 321; 5-((4-(2-methyl-2-phenylpropoxy)phenyl)methyl)- 2,4-Thiazolidinedione. Grade: 98%. CAS No. 74772-68-2. Molecular formula: C20H21NO3S. Mole weight: 355.45.
AL 34662
AL 34662 is a potent 5-HT2 receptor agonist with ocular hypotensive activity. Uses: Serotonin 5-ht2 receptor agonists. Synonyms: AL 34497; 1-((S)-2-aminopropyl)-1H-indazol-6-ol; 1H-Indazol-6-ol, 1-[(2S)-2-aminopropyl]-. Grade: ≥98%. CAS No. 210580-75-9. Molecular formula: C10H13N3O. Mole weight: 191.2.
AL-3803
AL-3803, a spiro derivative, has been found to have some extent of biological activity in drug researches. Synonyms: AL-3803; AL 3803; AL3803; (-)-AL03152; AC1MIXPX; (-)-AL03152; Spiro(9H-fluorene-9,4'-imidazolidine)-2',5'-dione, 2,7-difluoro-4-methoxy-, (S)-; (9S)-2,7-difluoro-4-methoxyspiro[fluorene-9,5'-imidazolidine]-2',4'-dione. Grade: 98%. CAS No. 145555-03-9. Molecular formula: C16H10F2N2O3. Mole weight: 316.26.
AL 6598
AL 6598 is the isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist that binds to DP receptors with a Ki value of 3.2 μM and demonstrates an EC50 value of 0.80 μM in an in vitro functional assay. Synonyms: propan-2-yl 2-[(Z)-4-[(1R,2R,3R,5R)-5-chloro-2-[(3R)-3-cyclohexyl-3-hydroxypropyl]-3-hydroxycyclopentyl]but-2-enoxy]acetate. Grade: ≥97%. CAS No. 170291-06-2. Molecular formula: C23H39ClO5. Mole weight: 431.
AL 8697
AL 8697 is an effective and selective p38α inhibitor and has been found to exhibit some antiinflammatory activities. Synonyms: AL 8697; AL8697; AL-8697; N-Cyclopropyl-3-[3-(1,1-dimethylethyl)-6,8-difluoro-1,2,4-triazolo[4,3-a]pyridin-7-yl]-5-fluoro-4-methylbenzamide. Grade: ≥98% by HPLC. CAS No. 1057394-06-5. Molecular formula: C21H21F3N4O. Mole weight: 402.41.
AL 8697
AL 8697. Group: Biochemicals. Grades: Purified. CAS No. 1057394-06-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
AL 8810
AL 8810 is a prostaglandin F2a analog and a selective FP prostanoid receptor antagonist. AL-8810 produced a concentration-dependent shift in the fluprostenol concentration-response curve, without significantly decreasing the maximal response. AL-8810 has weak agonist potency with EC50 of 261 +/- 44 nM (n = 3) and Emax = 19% (relative to the full FP receptor agonist cloprostenol) in A7r5 cells and EC50 of 186 +/- 63 nM (n = 3) and Emax = 23% in 3T3 fibroblasts. Uses: Prostaglandin antagonists. Synonyms: AL-8810; 246246-19-5; AL 8810; AL8810; (Z)-7-[(1R,2R,3S,5S)-2-[(E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxyprop-1-enyl]-3-fluoro-5-hydroxycyclopentyl]hept-5-enoic acid; 12QE8J6004; 5-Heptenoic acid, 7-((1R,2R,3S,5S)-2-((1E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxy-1-propen-1-yl)-3-fluoro-5-hydroxycyclopentyl)-, (5Z)-; 5-Heptenoic acid, 7-[(1R,2R,3S,5S)-2-[(1E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxy-1-propen-1-yl]-3-fluoro-5-hydroxycyclopentyl]-, (5Z)-; 5-Heptenoic acid, 7-((1R,2R,3S,5S)-2-((1E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxy-1-propenyl)-3-fluoro-5-hydroxycyclopentyl)-, (5Z)-. Grade: ≥98%. CAS No. 246246-19-5. Molecular formula: C24H31O4F. Mole weight: 402.5.
AL-8810
AL-8810 is a potent and selective antagonist of the PGF 2α receptor (FP receptor). AL-8810 is an activator of MAPK and ERK1/2. The Ki of the FP receptor of mouse 3T3 cells and rat A7r5 cells are 0.2±0.06 μM and 0.4±0.1 μM, respectively. AL-8810 can be used in the study of elevated intraocular pressure (OHT) and primary open-angle glaucoma (POAG)[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 246246-19-5. Pack Sizes: 1 mg. Product ID: HY-100449.
AL 8810 isopropyl ester
AL 8810 is a prostaglandin F2a analog and a selective FP prostanoid receptor antagonist. AL 8810 isopropyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular prostaglandin compounds such as Latanoprost and Travoprost. Synonyms: AL 8810 isopropyl ester; Propan-2-yl (Z)-7-[(1R,2R,3S,5S)-2-[(E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxyprop-1-enyl]-3-fluoro-5-hydroxycyclopentyl]hept-5-enoate; 5-Heptenoic acid, 7-[(1R,2R,3S,5S)-2-[(1E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxy-1-propen-1-yl]-3-fluoro-5-hydroxycyclopentyl]-, 1-methylethyl ester, (5Z)-; HMS3648C21; AKOS025294879; SR-01000946200; SR-01000946200-1; 9alpha, 15R- dihydroxy- 11beta- fluoro- 15- (2, 3- dihydro- 1H- inden- 2- yl)- 16, 17, 18, 19, 20- pentanor- prosta- 5Z, 13E- dien- 1- oic acid, isopropyl ester. Grade: ≥98%. CAS No. 208114-93-6. Molecular formula: C27H37FO4. Mole weight: 444.6.
AL 8810 methyl ester
AL 8810 is a prostaglandin F2a analog and a selective FP prostanoid receptor antagonist. AL 8810 methyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular prostaglandin compounds such as Latanoprost and Travoprost. Synonyms: AL 8810 methyl ester; 1176541-11-9; methyl (Z)-7-[(1R,2R,3S,5S)-2-[(E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxyprop-1-enyl]-3-fluoro-5-hydroxycyclopentyl]hept-5-enoate; CHEBI:186084; DTXSID001347566; methyl (Z)-7-[(1R,2R,3S,5S)-2-[(E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxyprop-1-enyl]-3-luoro-5-hydroxycyclopentyl]hept-5-enoate. Grade: ≥98%. CAS No. 1176541-11-9. Molecular formula: C25H33FO4. Mole weight: 416.5.
AL-9
AL-9 is a inhibitor of PI4KIIIα, with the IC50 of 0.57 μM, that can inhibit HCV replication[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 869218-90-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118525.