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The enzyme is involved in the biosynthesis of aklaviketone, an intermediate in the biosynthetic pathways leading to formation of several anthracycline antibiotics, including aclacinomycin, daunorubicin and doxorubicin. Group: Enzymes. Synonyms: dauD (gene name); aknH (gene name); dnrD (gene name); methyl aklanonate cyclase; methyl aklanonate-aklaviketone isomerase (cyclizing); aklaviketone lyase (decyclizing). Enzyme Commission Number: EC 5.5.1.23. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5624; aklanonic acid methyl ester cyclase; EC 5.5.1.23; dauD (gene name); aknH (gene name); dnrD (gene name); methyl aklanonate cyclase; methyl aklanonate-aklaviketone isomerase (cyclizing); aklaviketone lyase (decyclizing). Cat No: EXWM-5624.
aklanonic acid methyltransferase
The enzyme from the Gram-positive bacterium Streptomyces sp. C5 is involved in the biosynthesis of the anthracycline daunorubicin. Group: Enzymes. Synonyms: DauC; AAMT. Enzyme Commission Number: EC 2.1.1.288. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1895; aklanonic acid methyltransferase; EC 2.1.1.288; DauC; AAMT. Cat No: EXWM-1895.
aklaviketone reductase
The enzyme is involved in the synthesis of the aklavinone aglycone, a common precursor for several anthracycline antibiotics including aclacinomycins, daunorubicin and doxorubicin. The enzyme from the Gram-negative bacterium Streptomyces sp. C5 produces daunomycin. Group: Enzymes. Synonyms: dauE (gene name); aknU (gene name). Enzyme Commission Number: EC 1.1.1.362. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0279; aklaviketone reductase; EC 1.1.1.362; dauE (gene name); aknU (gene name). Cat No: EXWM-0279.
Aklavin
It is produced by the strain of Streptomyces galilaeus. It has the activity of resisting gram positive bacterium, negative bacterium, candida and ringworm. Synonyms: Aclacinomycin T; 1-Deoxypyrromycin; Aclacinomycin; Doxypyrromycin; NSC 100290; CHEBI:74351; 1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexapyranosyl)oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-; aklavine. CAS No. 60504-57-6. Molecular formula: C30H35NO10. Mole weight: 569.60.
Aklavinone
Aklavinone is an anthracycline drug with an antitumor effect. CAS No. 16234-96-1. Molecular formula: C22H20O8. Mole weight: 412.39.
aklavinone 12-hydroxylase
The enzymes from the Gram-positive bacteria Streptomyces peucetius and Streptomyces purpurascens participate in the biosynthesis of daunorubicin, doxorubicin and rhodomycins. The enzyme from Streptomyces purpurascens is an FAD monooxygenase. Group: Enzymes. Synonyms: DnrF; RdmE; aklavinone 11-hydroxylase (incorrect). Enzyme Commission Number: EC 1.14.13.180. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0779; aklavinone 12-hydroxylase; EC 1.14.13.180; DnrF; RdmE; aklavinone 11-hydroxylase (incorrect). Cat No: EXWM-0779.
aklavinone 7-L-rhodosaminyltransferase
Isolated from the bacterium Streptomyces galilaeus. Forms a complex with its accessory protein AknT, and has very low activity in its absence. The enzyme can also use dTDP-2-deoxy-β-L-fucose. Involved in the biosynthesis of other aclacinomycins. Group: Enzymes. Synonyms: AknS/AknT; aklavinone 7-β-L-rhodosaminyltransferase; dTDP-β-L-rhodosamine:aklavinone 7-α-L-rhodosaminyltransferase. Enzyme Commission Number: EC 2.4.1.326. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2563; aklavinone 7-L-rhodosaminyltransferase; EC 2.4.1.326; AknS/AknT; aklavinone 7-β-L-rhodosaminyltransferase; dTDP-β-L-rhodosamine:aklavinone 7-α-L-rhodosaminyltransferase. Cat No: EXWM-2563.
Aklomide
Aklomide is antiprotozoal agent against coccidiosis. Synonyms: 2-chloro-4-nitrobenzamide 2-Chloro-4-nitrobenzamide aklomide 3011-89-0 Aklomix Clomide Alkomide Benzamide, 2-chloro-4-nitro- component of Aklomix component of Novastat-W. CAS No. 3011-89-0. Molecular formula: C7H5ClN2O3. Mole weight: 200.58.
AKN-028
AKN-028, the FLT3/KIT kinase inhibitor, is an orally bioavailable protein tyrosine kinase inhibitor for FMS-related tyrosine kinase 3 (FLT3; STK1) and stem cell factor receptor (SCFR; KIT), with potential antineoplastic activity. FLT3/KIT kinase inhibitor AKN-028 binds to and inhibits both the wild-type and mutated forms of FLT3 and SCFR. This may result in an inhibition of tumor cell proliferation in cancer cell types that overexpress these receptor tyrosine kinases. Synonyms: AKN 028; AKN028; N2-(1H-Indol-5-yl)-6-(pyridin-4-yl)pyrazine-2,3-diamine; 2,3-Pyrazinediamine, N3-1H-indol-5-yl-5-(4-pyridinyl)-; N3-(1H-Indol-5-yl)-5-(4-pyridinyl)-2,3-pyrazinediamine. Grades: ≥95%. CAS No. 1175017-90-9. Molecular formula: C17H14N6. Mole weight: 302.33.
AKOS 90779
AKOS 90779. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS 90779;4,5-DICHLORO-2-PYRIDIN-2-YL-2H-PYRIDAZIN-3-ONE;AKOS BBV-017632;UKRORGSYN-BB BBV-017632. Product Category: Heterocyclic Organic Compound. CAS No. 78389-19-2. Molecular formula: C9H5Cl2N3O. Mole weight: 242.064. Purity: 0.96. IUPACName: 4,5-dichloro-2-pyridin-2-ylpyridazin-3-one. Canonical SMILES: C1=CC=NC(=C1)N2C(=O)C(=C(C=N2)Cl)Cl. Density: 1.546g/cm³. Product ID: ACM78389192. Alfa Chemistry ISO 9001:2015 Certified.
Akos akm00654
Akos akm00654. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MolPort-001-797-479, NSC164165, AKM00654, CID295009, STK413020, ZINC00112699, 1-(4-chlorophenyl)-3-naphthalen-1-ylurea, 13257-14-2. Product Category: Heterocyclic Organic Compound. CAS No. 13257-14-2. Molecular formula: C17H13ClN2O. Mole weight: 296.751. Purity: 0.96. IUPACName: 1-(4-chlorophenyl)-3-naphthalen-1-ylurea. Canonical SMILES: C1=CC=C2C(=C1)C=CC=C2NC(=O)NC3=CC=C(C=C3)Cl. Density: 1.374g/cm³. Product ID: ACM13257142. Alfa Chemistry ISO 9001:2015 Certified.
Akos b004665
Akos b004665. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS B004665;CHEMBRDG-BB 7381871;2-CHLORO-4-FORMYL-6-METHOXYPHENYL ACETATE;ACETIC ACID2-CHLORO-4-FORMYL-6-METHOXY-PHENYL ESTER;ART-CHEM-BB B004665;VITAS-BB TBB008051. Product Category: Heterocyclic Organic Compound. CAS No. 63055-10-7. Molecular formula: C10H9ClO4. Product ID: ACM63055107. Alfa Chemistry ISO 9001:2015 Certified.
Akos b004827
Akos b004827. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS B004827;ASISCHEM R44478;CHEMBRDG-BB 6439485;(2-BROMO-4-FORMYL-6-METHOXYPHENOXY)ACETIC ACID;ART-CHEM-BB B004827;VITAS-BB TBB001423. Product Category: Heterocyclic Organic Compound. CAS No. 677012-43-0. Molecular formula: C10H9BrO5. Mole weight: 289.08. Product ID: ACM677012430. Alfa Chemistry ISO 9001:2015 Certified.
Akos b013860
Akos b013860. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TIMTEC-BB SBB009318;AKOS B013860;CHEMBRDG-BB 3013860;ART-CHEM-BB B013860;2-(2-Isopropylphenoxy)propanoic acid. Product Category: Heterocyclic Organic Compound. CAS No. 161790-37-0. Molecular formula: C12H16O3. Mole weight: 208.25. Product ID: ACM161790370. Alfa Chemistry ISO 9001:2015 Certified.
Akos b013910
Akos b013910. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBRDG-BB 3013910;ART-CHEM-BB B013910;AKOS B013910;2-(2-Chloro-5-methylphenoxy)-2-methylpropanoic acid. Product Category: Heterocyclic Organic Compound. CAS No. 588692-86-8. Molecular formula: C11H13ClO3. Mole weight: 228.67. Product ID: ACM588692868. Alfa Chemistry ISO 9001:2015 Certified.
Akos b015243
Akos b015243. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBRDG-BB 3015243;ART-CHEM-BB B015243;AKOS B015243;2-(4-Methyl-2-nitrophenoxy)propanohydrazide. Product Category: Heterocyclic Organic Compound. CAS No. 588678-31-3. Molecular formula: C10H13N3O4. Mole weight: 239.23. Product ID: ACM588678313. Alfa Chemistry ISO 9001:2015 Certified.
Akos b017986
Akos b017986. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BUTTPARK 83\07-41;CHEMBRDG-BB 3017986;ART-CHEM-BB B017986;AKOS B017986;5-(5-Chloro-2-methoxyphenyl)-4-methyl-4H-1,2,4-triazole-3-thiol;Albb-003285. Product Category: Heterocyclic Organic Compound. CAS No. 370855-34-8. Molecular formula: C10H10ClN3OS. Mole weight: 255.72. Product ID: ACM370855348. Alfa Chemistry ISO 9001:2015 Certified.
AKOS B018304
AKOS B018304 is a potent inhibitor of chikungunya virus with low micromolar activity. Synonyms: (E)-2-Mercapto-5-(2-Nitrobenzylidene)Thiazol-4(5H)-One; O-Nitrobenzalrhodanin. Grades: 98%. CAS No. 6308-22-1. Molecular formula: C10H6N2O3S2. Mole weight: 266.3.
Akos b023208
Akos b023208. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS B023208;ART-CHEM-BB B023208;CHEMBRDG-BB 5524838;2-(4-METHOXYPHENYL)-N-(1-NAPHTHYLMETHYL)ETHANAMINE. Product Category: Heterocyclic Organic Compound. CAS No. 416889-35-5. Molecular formula: C20H21NO. Mole weight: 291.39. Product ID: ACM416889355. Alfa Chemistry ISO 9001:2015 Certified.
Akos b023217
Akos b023217. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ART-CHEM-BB B023217;CHEMBRDG-BB 5572794;AKOS B023217;TIMTEC-BB SBB009636;(1,3-BENZODIOXOL-5-YLMETHYL)ISOPROPYLAMINE;BENZO[1,3]DIOXOL-5-YLMETHYL-ISOPROPYL-AMINE;UKRORGSYN-BB BBV-164851. Product Category: Heterocyclic Organic Compound. CAS No. 68291-92-9. Molecular formula: C11H15NO2. Mole weight: 193.24. Product ID: ACM68291929. Alfa Chemistry ISO 9001:2015 Certified.
Akos b023249
Akos b023249. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS B023249;ART-CHEM-BB B023249;CHEMBRDG-BB 5535937;TIMTEC-BB SBB009642;(2,4-DIMETHOXYBENZYL)[2-(4-FLUOROPHENYL)ETHYL]AMINE. Product Category: Heterocyclic Organic Compound. CAS No. 355382-64-8. Molecular formula: C17H20FNO2. Mole weight: 289.34. Product ID: ACM355382648. Alfa Chemistry ISO 9001:2015 Certified. Categories: N-(2,4-Dimethoxybenzyl)-2-(4-fluorophenyl)ethanamine hydrochloride.
Akos b023256
Akos b023256. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBRDG-BB 5549545;ART-CHEM-BB B023256;AKOS B023256;TIMTEC-BB SBB009643;(4-BROMOBENZYL)[2-(3,4-DIMETHOXYPHENYL)ETHYL]AMINE. Product Category: Heterocyclic Organic Compound. CAS No. 133344-77-1. Molecular formula: C17H20BrNO2. Mole weight: 350.25. Product ID: ACM133344771. Alfa Chemistry ISO 9001:2015 Certified.
AKOS B028903
AKOS B028903 (CAS# 692275-23-3 ) is a useful research chemical. Synonyms: AKOS B028903; CHEMBRDG-BB 7420349; 2-CHLORO-5-ETHOXY-4-PROPOXY-BENZALDEHYDE; ART-CHEM-BB B028903; VITAS-BB TBB009798. Grades: 95 %. CAS No. 692275-23-3. Molecular formula: C12H15ClO3. Mole weight: 242.70.
Akos b028906
Akos b028906. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS B028906;CHEMBRDG-BB 7389354;2-CHLORO-5-ETHOXY-4-ISOPROPOXY-BENZALDEHYDE;ART-CHEM-BB B028906;VITAS-BB TBB009799. Product Category: Heterocyclic Organic Compound. CAS No. 692267-55-3. Molecular formula: C12H15ClO3. Mole weight: 242.701. Product ID: ACM692267553. Alfa Chemistry ISO 9001:2015 Certified. Categories: 2-CHLORO-5-ETHOXY-4-ISOPROPOXYBENZALDEHYDE.
AKOS B028906
AKOS B028906 (CAS# 692267-55-3 ) is a useful research chemical. Synonyms: AKOS B028906; CHEMBRDG-BB 7389354; 2-CHLORO-5-ETHOXY-4-ISOPROPOXY-BENZALDEHYDE; ART-CHEM-BB B028906; VITAS-BB TBB009799. Grades: 95 %. CAS No. 692267-55-3. Molecular formula: C12H15ClO3. Mole weight: 242.70.
Akos b029140
Akos b029140. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBRDG-BB 7745536;AKOS B029140;3-(5-OXO-3-PROPYL-4,5-DIHYDRO-1H-PYRAZOL-1-YL)BENZOIC ACID;3-(5-OXO-3-PROPYL-4,5-DIHYDRO-PYRAZOL-1-YL)-BENZOIC ACID;ART-CHEM-BB B029140;VITAS-BB TBB009862. Product Category: Heterocyclic Organic Compound. CAS No. 701221-57-0. Molecular formula: C13H14N2O3. Product ID: ACM701221570. Alfa Chemistry ISO 9001:2015 Certified.
AKOS B029152
AKOS B029152 (CAS# 700849-61-2 ) is a useful research chemical. Synonyms: AKOS B029152; CHEMBRDG-BB 7726699; 4-(5-OXO-3-PROPYL-2,5-DIHYDRO-1H-PYRAZOL-1-YL)BENZOIC ACID; 4-(5-OXO-3-PROPYL-2,5-DIHYDRO-PYRAZOL-1-YL)-BENZOIC ACID; ART-CHEM-BB B029152; VITAS-BB TBB009868. Grades: 95 %. CAS No. 700849-61-2. Molecular formula: C13H14N2O3. Mole weight: 246.26.
Akos b029363
Akos b029363. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS B029363;CHEMBRDG-BB 7454605;5-CHLORO-2-ISOPROPOXY-3-METHOXY-BENZALDEHYDE;ART-CHEM-BB B029363. Product Category: Heterocyclic Organic Compound. CAS No. 827593-20-4. Molecular formula: C11H13ClO3. Mole weight: 228.674. Product ID: ACM827593204. Alfa Chemistry ISO 9001:2015 Certified. Categories: 5-CHLORO-2-ISOPROPOXY-3-METHOXYBENZALDEHYDE.
AKOS B029817
AKOS B029817 (CAS# 590376-72-0 ) is a useful research chemical. Synonyms: AKOS B029817; CHEMBRDG-BB 7763392; 2-(4-CHLORO-2-FORMYLPHENOXY)ACETAMIDE; ART-CHEM-BB B029817; VITAS-BB TBB002769. Grades: 95 %. CAS No. 590376-72-0. Molecular formula: C9H8ClNO3. Mole weight: 213.62.
Akos b033181
Akos b033181. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS B033181;AKOS BC-0108;TIMTEC-BB SBB011152;2-(2-(PYRROLIDIN-1-YL)ETHOXY)ANILINE;2-(2-PYRROLIDIN-1-YL-ETHOXY)-PHENYLAMINE;ART-CHEM-BB B033181;ART-CHEM-BB B037560;VITAS-BB TBB001496. Product Category: Heterocyclic Organic Compound. CAS No. 878733-59-6. Molecular formula: C12H18N2O. Mole weight: 206.284120 [g/mol]. Purity: 0.96. IUPACName: 2-(2-pyrrolidin-1-ylethoxy)aniline. Canonical SMILES: C1CCN(C1)CCOC2=CC=CC=C2N. Product ID: ACM878733596. Alfa Chemistry ISO 9001:2015 Certified.
Akos bb-2983
Akos bb-2983. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BB-2983;CHEMBRDG-BB 6698389;[4-(3-FORMYL-2,5-DIMETHYL-1H-PYRROL-1-YL)PHENOXY]ACETIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 662154-28-1. Molecular formula: C15H15NO4. Mole weight: 273.28. Product ID: ACM662154281. Alfa Chemistry ISO 9001:2015 Certified.
Akos bb-3561
Akos bb-3561. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBRDG-BB 6491933;AKOS BB-3561;1-[4-(DIMETHYLAMINO)PHENYL]-2,5-DIMETHYL-1H-PYRROLE-3-CARBALDEHYDE. Product Category: Heterocyclic Organic Compound. CAS No. 32570-93-7. Molecular formula: C15H18N2O. Mole weight: 242.32. Product ID: ACM32570937. Alfa Chemistry ISO 9001:2015 Certified.
Akos bb-3568
Akos bb-3568. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBRDG-BB 9003047;AKOS BB-3568;4-(3-ACETYL-2,5-DIMETHYL-1H-PYRROL-1-YL)BENZOIC ACID. Product Category: Heterocyclic Organic Compound. CAS No. 870540-39-9. Molecular formula: C15H15NO3. Product ID: ACM870540399. Alfa Chemistry ISO 9001:2015 Certified.
Akos bb-9394
Akos bb-9394. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BB-9394;TIMTEC-BB SBB011112;2-((PYRROLIDIN-1-YL)METHYL)BENZOIC ACID;OTAVA-BB 7020661509. Product Category: Heterocyclic Organic Compound. CAS No. 876717-98-5. Molecular formula: C12H15NO2. Mole weight: 205.253000 [g/mol]. Purity: 0.96. IUPACName: 2-(pyrrolidin-1-ylmethyl)benzoic acid. Canonical SMILES: C1CCN(C1)CC2=CC=CC=C2C(=O)O. Product ID: ACM876717985. Alfa Chemistry ISO 9001:2015 Certified.
Akos bb-9805
Akos bb-9805. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-ethyl-2-pyrrolidin-1-ylethanamine, N-ethyl-2-(1-pyrrolidinyl)ethanamine, ST088030, 138356-55-5, ethyl(2-pyrrolidinylethyl)amine, AGN-PC-003SQO, SureCN5430626, CTK4C1222, MolPort-004-947-147, 1-Pyrrolidineethanamine, N-ethyl-, SBB007481, AKOS004120645, ethyl[2-(pyrrolidin-1-yl)ethyl]amine, AG-D-77613, MCULE-2763787370, KB-58188, KB-258727, FT-0683213, I05-1155. Product Category: Heterocyclic Organic Compound. CAS No. 138356-55-5. Molecular formula: C8H18N2. Mole weight: 142.241920 [g/mol]. Purity: 0.96. IUPACName: N-ethyl-2-pyrrolidin-1-ylethanamine. Canonical SMILES: CCNCCN1CCCC1. Density: 0.894g/cm³. Product ID: ACM138356555. Alfa Chemistry ISO 9001:2015 Certified.
AKOS BBS-00000303
AKOS BBS-00000303. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IFLAB-BB F1420-0302;AKOS BBS-00000303;2-AMINO-BENZOTHIAZOLE-6-SULFONIC ACID METHYLAMIDE. Product Category: Heterocyclic Organic Compound. CAS No. 18101-53-6. Molecular formula: C8H9N3O2S2. Mole weight: 243.31. Product ID: ACM18101536. Alfa Chemistry ISO 9001:2015 Certified.
AKOS BBS-00000304
AKOS BBS-00000304. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BBS-00000304;IFLAB-BB F1420-0612;2-AMINO-BENZOTHIAZOLE-6-SULFONIC ACID DIMETHYLAMIDE. Product Category: Heterocyclic Organic Compound. CAS No. 17901-13-2. Molecular formula: C9H11N3O2S2. Mole weight: 257.33. Product ID: ACM17901132. Alfa Chemistry ISO 9001:2015 Certified.
AKOS BBS-00000987
AKOS BBS-00000987. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BBS-00000987;IFLAB-BB F1990-0009;4-((3,5-DIMETHYL-1H-PYRAZOL-4-YL)SULFONYL)MORPHOLINE. Product Category: Heterocyclic Organic Compound. CAS No. 80466-86-0. Molecular formula: C9H15N3O3S. Mole weight: 245.3. Product ID: ACM80466860. Alfa Chemistry ISO 9001:2015 Certified. Categories: 4-[(3,5-dimethyl-1H-pyrazol-4-yl)sulfonyl]morpholine.
Akos bbs-00000988
Akos bbs-00000988. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IFLAB-BB F0918-6658;AKOS BBS-00000988;1-(3,5-DIMETHYL-1H-PYRAZOLE-4-SULFONYL)-PIPERIDINE. Product Category: Heterocyclic Organic Compound. CAS No. 91141-46-7. Molecular formula: C10H17N3O2S. Mole weight: 243.33. Product ID: ACM91141467. Alfa Chemistry ISO 9001:2015 Certified.
Akos bbs-00001550
Akos bbs-00001550. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ethyl 7-methoxy-2-methylquinoline-3-carboxylate, SBB039122, 86210-91-5, 7-Methoxy-2-methylquinoline-3-carboxylic acid ethyl ester, ZINC08253055, AC1NHA95, SureCN1574317, MolPort-000-499-443, STL227739, AKOS000267314, AB23714, MCULE-5971957867, KB-250011, ST45174704, T5559039, 7-METHOXY-2-METHYL-3-QUINOLINECARBOXYLIC ACID ETHYL ESTER. Product Category: Heterocyclic Organic Compound. CAS No. 86210-91-5. Molecular formula: C14H15NO3. Mole weight: 245.27. Purity: 0.96. IUPACName: ethyl 7-methoxy-2-methylquinoline-3-carboxylate. Canonical SMILES: CCOC(=O)C1=C(N=C2C=C(C=CC2=C1)OC)C. Density: 1.159g/cm³. Product ID: ACM86210915. Alfa Chemistry ISO 9001:2015 Certified.
Akos bbs-00001917
Akos bbs-00001917. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IFLAB-BB F2124-0038;CHEMBRDG-BB 9025926;AKOS BBS-00001917;(5-ETHYL-1-BENZOFURAN-3-YL)ACETIC ACID;AKOS A0602-0443;OTAVA-BB 7118560541. Product Category: Heterocyclic Organic Compound. CAS No. 882248-24-0. Molecular formula: C12H12O3. Mole weight: 204.22. Product ID: ACM882248240. Alfa Chemistry ISO 9001:2015 Certified.
Akos bbs-00005383
Akos bbs-00005383. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BBS-00005383;ASISCHEM C33117;1H-[1,2]DITHIOLO[3,4-C]QUINOLINE-1-THIONE, 5-(CHLOROACETYL)-4,5-DIHYDRO-4,4,7,8-TETRAMETHYL-;5-(CHLOROACETYL)-4,5-DIHYDRO-4,4,7,8-TETRAMETHYL-1H-[1,2]DITHIOLO[3,4-C]QUINOLINE-1-THIONE. Product Category: Heterocyclic Organic Compound. CAS No. 352016-99-0. Molecular formula: C16H16ClNOS3. Mole weight: 369.95. Product ID: ACM352016990. Alfa Chemistry ISO 9001:2015 Certified.
Akos bbs-00005387
Akos bbs-00005387. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ASISCHEM U52582;CHEMBRDG-BB 5101452;AKOS BBS-00005387;6-CHLORO-N,N'-DIPHENYL-1,3,5-TRIAZINE-2,4-DIAMINE;[4-(anilino)-6-chloro-s-triazin-2-yl]-phenyl-amine;6-chloro-2-N,4-N-di(phenyl)-1,3,5-triazine-2,4-diamine;6-chloro-N2,N4-di(phenyl)-1,3,5-triazine-2,4. Product Category: Heterocyclic Organic Compound. CAS No. 1973-9-7. Molecular formula: C15H12ClN5. Mole weight: 297.74. Product ID: ACM1973097. Alfa Chemistry ISO 9001:2015 Certified. Categories: NSC 76482.
Akos bbs-00005437
Akos bbs-00005437. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ASISCHEM C34560;AKOS BBS-00005437;1H-[1,2]DITHIOLO[3,4-C]QUINOLINE-1-THIONE, 5-(2-CHLORO-1-OXOPROPYL)-4,5-DIHYDRO-4,4,8-TRIMETHYL-;5-(2-CHLORO-1-OXOPROPYL)-4,5-DIHYDRO-4,4,8-TRIMETHYL-1H-[1,2]DITHIOLO[3,4-C]QUINOLINE-1-THIONE. Product Category: Heterocyclic Organic Compound. CAS No. 375360-52-4. Molecular formula: C16H16ClNOS3. Mole weight: 369.95. Product ID: ACM375360524. Alfa Chemistry ISO 9001:2015 Certified.
Akos bbs-00005522
Akos bbs-00005522. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BBS-00005522;ASISCHEM C37647;2-QUINAZOLINAMINE, 4-METHYL-N-[1,4,5,6-TETRAHYDRO-5-(2-PHENYLETHYL)-1,3,5-TRIAZIN-2-YL]-;4-METHYL-N-[1,4,5,6-TETRAHYDRO-5-(2-PHENYLETHYL)-1,3,5-TRIAZIN-2-YL]-2-QUINAZOLINAMINE. Product Category: Heterocyclic Organic Compound. CAS No. 672338-32-8. Molecular formula: C20H22N6. Mole weight: 346.43. Product ID: ACM672338328. Alfa Chemistry ISO 9001:2015 Certified.
Akos bbs-00006061
Akos bbs-00006061. Uses: Designed for use in research and industrial production. Additional or Alternative Names: CHEMBRDG-BB 7113032;AKOS BBS-00006061;3-(4-BROMOPHENYL)-7-HYDROXY-2-METHYL-4H-CHROMEN-4-ONE. Product Category: Heterocyclic Organic Compound. CAS No. 610758-58-2. Molecular formula: C16H11BrO3. Mole weight: 331.16. Product ID: ACM610758582. Alfa Chemistry ISO 9001:2015 Certified.
Akos bbs-00008052
Akos bbs-00008052. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BBS-00008052;CHEMBRDG-BB 5363606;(2E)-3-(2-CHLOROPHENYL)-N-(3-HYDROXYPHENYL)ACRYLAMIDE;AKOS A1230-3081. Product Category: Heterocyclic Organic Compound. CAS No. 300825-48-3. Molecular formula: C15H12ClNO2. Mole weight: 273.71. Product ID: ACM300825483. Alfa Chemistry ISO 9001:2015 Certified. Categories: (2E)-3-(2-chlorophenyl)-N-(3-hydroxyphenyl)prop-2-enamide.
Akos bbs-00008199
Akos bbs-00008199. Uses: Designed for use in research and industrial production. Additional or Alternative Names: OTAVA-BB BB7015500288;AKOS BBS-00008199;AKOS A1230-7211;OTAVA-BB 7015500288. Product Category: Heterocyclic Organic Compound. CAS No. 91153-72-9. Molecular formula: C14H15NO4. Mole weight: 261.27. Product ID: ACM91153729. Alfa Chemistry ISO 9001:2015 Certified.
Akos bc-1738
Akos bc-1738. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TOSLAB 97274;AKOS BC-1738;CHEMBRDG-BB 6034708;2-[2-(4-BROMOPHENYL)-2-OXOETHOXY]BENZAMIDE. Product Category: Heterocyclic Organic Compound. CAS No. 337925-74-3. Molecular formula: C15H12BrNO3. Mole weight: 334.16. Product ID: ACM337925743. Alfa Chemistry ISO 9001:2015 Certified.
Akos bc-1945
Akos bc-1945. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BC-1945;CHEMBRDG-BB 9071388;3-(3,4-DIMETHYLPHENOXY)-N-METHYL-1-PROPANAMINE;UKRORGSYN-BB BBV-182444. Product Category: Heterocyclic Organic Compound. CAS No. 915923-36-3. Molecular formula: C12H19NO. Mole weight: 193.288. Product ID: ACM915923363. Alfa Chemistry ISO 9001:2015 Certified.
Akos bc-1949
Akos bc-1949. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS BC-1949;CHEMBRDG-BB 9070580;N-METHYL-3-(4-METHYLPHENOXY)-1-PROPANAMINE;UKRORGSYN-BB BBV-253231. Product Category: Heterocyclic Organic Compound. CAS No. 915923-08-9. Molecular formula: C11H17NO. Mole weight: 179.261. Product ID: ACM915923089. Alfa Chemistry ISO 9001:2015 Certified.
Akos bc-3058
Akos bc-3058. Uses: Designed for use in research and industrial production. Additional or Alternative Names: IFLAB-BB F0898-0214;AKOS BC-3058;N-[1-AMINO-1-PHENYL-METH-(Z)-YLIDENE]-BENZENESULFONAMIDE. Product Category: Heterocyclic Organic Compound. CAS No. 14067-77-7. Molecular formula: C13H12N2O2S. Mole weight: 260.31. Product ID: ACM14067777. Alfa Chemistry ISO 9001:2015 Certified.
Akos pao-0857
Akos pao-0857. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS PAO-0857;CHEMBRDG-BB 4002917;3-(1-METHYL-1H-PYRAZOL-4-YL)PROPAN-1-OL. Product Category: Heterocyclic Organic Compound. CAS No. 192661-38-4. Molecular formula: C7H12N2O. Mole weight: 140.18. Product ID: ACM192661384. Alfa Chemistry ISO 9001:2015 Certified.
Akos pao-1153
Akos pao-1153. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS PAO-1153;3-Isobutyl-1H-pyrazole. Product Category: Heterocyclic Organic Compound. CAS No. 98816-40-1. Molecular formula: C7H12N2. Product ID: ACM98816401. Alfa Chemistry ISO 9001:2015 Certified.
AKR1C1 Inhibitor, 5-PBSA
A cell-permeable salicylic acid compound that acts as a highly potent, active-site directed and substrate competitive AKR1C1 inhibitor (Ki=4nM) with moderate to excellent selectivity over AKR1C2, AKR1C3 and AKR1C4 (Ki=0.087, 4.2 and 18.2uM, respectively). Shown to inhibit the metabolism of progesterone by AKR1C1 (IC50=460nM in AKR1C1 overexpressing BAECs).CAS No.4906-68-7. Group: Biochemicals. Alternative Names: Aldo-Keto Reductase family 1 member C1 Inhibitor, 5-PBSA, 3-Bromo-5-phenylsalicylic acid, 20α-Hydroxysteroid Dehydrogenase Inhibitor, 5-PBSA. Grades: Highly Purified. CAS No. 4906-68-7. Pack Sizes: 25mg. Molecular Formula: C??H?BrO?. US Biological Life Sciences.
A cell-permeable 3-phenyl-aminobenzoate compound that acts as a potent, competitive, reversible, active-site targeting inhibitor of aldo-keto reductase 1C3 (AKR1C3; type 5 17b-hydroxysteroid dehydrogenase) (IC50 = 60nM) with excellent selectivity over other closely related human AKR isoforms (IC50 = 22.7, 15.4, 62.7, >50, and >50uM for and AKR1C1, AKR1C2, AKR1C4, AKR1B1 and AKR1B10, respectively. Exhibits a weak inhibitory effect on cyclooxygenase 1 and 2 (IC50 = 100uM). Shown to efficiently block the AKR1C3-mediated production of testosterone in LNCaP-AKR1C3 cells (~10uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Akrobomycin
It is produced by the strain of Actinomadura reseoviolacea 129-AVI. It has anti-gram-negative bacteria, ringworm and tumor activity. Synonyms: 9,10-Anhydro-13-deoxocarminomycin; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-8-ethyl-9,10-dihydro-1,6,11-trihydroxy-, (S)-; DTXSID601008673; LS-94000; 3-Ethyl-5,10,12-trihydroxy-6,11-dioxo-1,2,6,11-tetrahydrotetracen-1-yl 3-amino-2,3,6-trideoxyhexopyranoside; Akrobomycin; Rubomycin Q1. CAS No. 89156-94-5. Molecular formula: C26H27NO8. Mole weight: 481.49.
Akt1 and Akt2-IN-1
Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 and Akt2 with the IC50 of 3.5 nM and 42 nM respectively. It has potent and balanced activity. It is dependent on the PH-domain for Akt inhibition. It is selective for Akt1/2 over Akt3 and is highly selective over other members of the AGC family of kinases in vitro. It has potent inhibitory activity against Akt1 and Akt 2 in vivo in a mouse lung and efficacy in a tumor xenograft model. It has moderate activity in an hERG binding assay and is a substrate for human P-glycoprotein. It also shows good physical properties with a human plasma protein binding. Uses: Akt1 and akt2-in-1 has potent inhibitory activity against akt1 and akt 2 and efficacy in a tumor xenograft model. Synonyms: Akt Inhibitor 17; Akti_2008; Akti 2008; Akti2008; Akti-2008; Akt Inhibitor 17; Akt-Inhibitor-17; AktInhibitor17; 3-Phenyl-2-[4-[[4-[5-(2-pyridinyl)-1H-1,2,4-triazol-3-yl]-1-piperidinyl]methyl]phenyl]-1,6-Naphthyridin-5(6H)-one;Akti_2008;3-phenyl-2-[4-[[4-(3-pyridin-2-yl-1H-1,2,4-triazol-5-yl)piperidin-1-yl]methyl]phenyl]-6H-1,6-naphthyridin-5-one. Grades: >98%. CAS No. 893422-47-4. Molecular formula: C33H29N7O. Mole weight: 539.63.
Akt Activator II, SC79 (Ethyl-2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate)
A cell-permeable and blood-brain barrier permeant HA14-1 analog that interacts with Akt PH domain PtdIns(3,4,5)P3- (PIP3) binding pocket, rendering Akt in a conformation susceptible to phosphorylation by upstream kinases. Shown to enhance both basal and receptor-mediated Akt phosphorylation (Thr308 and Ser473; 2 to 4ug/ml) with concomitant inhibition Akt membrane translocation in various cell cultures. Efficiently reduces glutamate-induced neurotoxicity both in primary neuron cultures (EC50 = 4ug/ml) in vitro and in a murine MCAO model (40mg/kg, i.p.) in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 305834-79-1. Pack Sizes: 25mg. Molecular Formula: C??H??ClN?O?. US Biological Life Sciences.
Worldwide
Akt Control Cell Extracts (Rac PKa, PKBa)
Akt Control Cell Extracts (Rac PKa, PKBa). Group: Biologicals. Grades: Lysate. Pack Sizes: 10Blots. US Biological Life Sciences.
Worldwide
Akt, dephosphorylated Positive Control (Ser473) (Rac PKa, PKBa)
Positive control for A1124-02D. Group: Molecular Biology. Pack Sizes: 200ul. US Biological Life Sciences.
Worldwide
Akti-1/2
Akti-1/2. Group: Biochemicals. Alternative Names: 1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one. Grades: Highly Purified. CAS No. 612847-09-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C34H29N7O. US Biological Life Sciences.
Allosteric Akt (PKB) inhibitors used in synergistic combination therapy for the treatment of cancer. Group: Biochemicals. Alternative Names: 1,3-Dihydro-1-[1-[[4-(6-phenyl-1H-imidazo[4,5-g]guinoxalin-7-yl)phenyl]methyl]4-piperidinyl]-2H-benzimidazol-2-one. Grades: Highly Purified. CAS No. 612847-09-3. Pack Sizes: 2mg. US Biological Life Sciences.
Worldwide
Akt-I-1,2 HCl
Akt-I-1,2 is a selective, non-ATP-competitive Akt1 and Akt2 inhibitor. Synonyms: Akt I 1,2 HCl; AktI1,2 HCl; Benzenemethanamine, alpha,alpha-dimethyl-4-(3-phenyl-2-quinoxalinyl)-, hydrochloride (1:1). CAS No. 473382-50-2. Molecular formula: C23H22ClN3. Mole weight: 375.90.
AKTide-2T
AKTide-2T, a peptide substrate for Akt/PKB, has been found to act as an inhibitor and mimics the optimal phosphorylation sequence of Akt. Synonyms: AKTide-2T; 324029-01-8; ARKRERTYSFGHHA; AKOS024457090; PD079315. Grades: ≥95% by HPLC. CAS No. 324029-01-8. Molecular formula: C74H114N28O20. Mole weight: 1715.89.
AKTide-2T
AKTide-2T. Group: Biochemicals. Grades: Purified. CAS No. 324029-01-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
AKT-IN-23
AKT-IN-23 is an AKT inhibitor. AKT-IN-23 can be used in cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1226801-23-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-161704.
Cell-permeable. A potent and selective inhibitor of Akt1/Akt2 activity (IC?? = 58nM (Akt1), 210nM (Akt2) and 2.12uM (Akt3) in in vitro kinase assays). The inhibition appears to be pleckstrin homology (PH) domain-dependent. It does not exhibit any inhibitory effect against PH domain-lacking Akts, or other closely related AGC family kinases, PKA, PKC, and SGK, even at concentrations (50uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 612847-09-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Akt Inhibitor IV
Akt inhibitor IV is an inhibitor of Akt activation that inhibits Akt-mediated nuclear export of Forkhead box class O transcription factor 1a (FOXO1a; IC50 = 625 nM) and reduces phosphorylation of Akt at Ser473 and Thr308 in a dose-dependent manner. Synonyms: 5-(2-Benzothiazolyl)-3-ethyl-2-[2-(methylphenylamino)ethenyl]-1-phenyl-1H-benzimidazolium iodide. Grades: ≥95%. CAS No. 681281-88-9. Molecular formula: C31H27N4S·I. Mole weight: 614.6.
AKT inhibitor IV
Akt inhibitor-IV (AKTIV) acts as a PI3K-Akt inhibitor at the E isomer (HY-14971), with potent cytotoxicity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AKTIV. CAS No. 681281-88-9. Pack Sizes: 1 mg. Product ID: HY-14971A.