A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
AI-3. Group: Biochemicals. Grades: Purified. CAS No. 882288-28-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Aib18, Exendin-4
Exendin-4 (Exenatide), an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Synonyms: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Aib-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Molecular formula: C189H291N51O61S. Mole weight: 4285.97.
Aib2, Exendin-4
Exendin-4 (Exenatide), an agonist of glucagon-like peptide 1 (GLP-1) receptor, induces release of insulin after food intake. Synonyms: His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Molecular formula: C186H286N50O60S. Mole weight: 4214.89.
Aibellin
It is produced by the strain of Vertocimonos poriurn ellipticum D1528. Alberin can enhance ruminant stomach fermentation, increase propionate production and reduce methane production caused by microorganisms in the stomach. Synonyms: AlamethicinI,2-L-alanine-9-L-phenylalanine-12-(2-methylalanine)-19-[N-[1-[[(2-hydroxyethyl)amino]methyl]-2-phenylethyl]-L-a-glutamine]-; L-a-Glutamine,N-acetyl-2-methylalanyl-L-alanyl-2-methylalanyl-L-alanyl-2-methylalanyl-L-alanyl-L-glutaminyl-2-methylalanyl-L-phenylalanyl-2-methylalanylglycyl-2-methylalanyl-2-methylalanyl-L-prolyl-L-valyl-2-methylalanyl-2-methylalanyl-L-a-glutamyl-N-[1-[[(2-hydroxyethyl)amino]methyl]-2-phenylethyl]-,(S)-. CAS No. 151036-29-2. Molecular formula: C94H147N21O27. Mole weight: 2003.29.
AIBN
AIBN. CAS No. 78-67-1. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
AICAR
Cell permeable AMP-activated protein kinase (AMPK) activator. Insulin mimetic. Adipocyte differentiation inhibitor. Apoptosis inducer. PPARalpha inhibitor. mTOR inhibitor. P70S6K inhibitor. LPS-induced TNFalpha production inhibitor. TORC2 phosphorylation inducer. Anti-inflammatory. Anti-tumor compound. Autophagy inhibitor. HSP90 inhibitor. Group: Biochemicals. Alternative Names: 5-Aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside. Grades: Highly Purified. CAS No. 2627-69-2. Pack Sizes: 10mg, 50mg, 100mg. Molecular Formula: C9H14N4O5. US Biological Life Sciences.
Worldwide
AICAR
AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR is also an autophagy, YAP and mitophagy inhibitor. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR inhibits autophagy through a mechanism independent of AMPK activity[1][2][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acadesine; AICA Riboside. CAS No. 2627-69-2. Pack Sizes: 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-13417.
AICAR 3',5'-cyclic phosphate
AICAR 3',5'-cyclic phosphate. Group: Biochemicals. Alternative Names: 5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranosyl 3':5'-cyclic-monophosphate; 5-Amino-1-(3,5-O-phosphinico-b-D-ribofuranosyl)-1H-imidazole-4-carboxamide; NSC 371796. Grades: Highly Purified. CAS No. 35908-14-6. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C9H13N4O7P. US Biological Life Sciences.
Worldwide
AICAR 3',5'-Cyclic Phosphate
A cyclic nucleotide with protein kinase and phosphodiesterase activity. Synonyms: 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 3':5'-cyclic-monophosphate; 5-Amino-1-(3,5-O-phosphinico-β-D-ribofuranosyl)-1H-imidazole-4-carboxamide; NSC 371796. Grade: 94%. CAS No. 35908-14-6. Molecular formula: C9H13N4O7P. Mole weight: 320.2.
AICAR 3,5-Cyclic Phosphate
A cyclic nucleotides with protein kinase and phosphodiesterase activity. Group: Biochemicals. Alternative Names: 5-Aminoimidazole-4-carboxamide-1- β-D-ribofuranosyl 3:5-cyclic-monophosphate;5-Amino-1-(3,5-O-phosphinico- β-D-ribofuranosyl)-1H-imidazole-4-carboxamide; NSC 371796. Grades: Highly Purified. CAS No. 35908-14-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
AICAR-5'-MP / ZMP
AICAR-5'-MP is an analogue of AICA-riboside, an alternative of 5'-AMP. AICAR-5'-MP is a purine precursor with antineoplastic activity and can be used in the study of type 2 diabetes. It can activate AMP-activated protein kinase. Synonyms: 1H-Imidazole-4-carboxamide, 5-amino-1-(5-O-phosphono-β-D-ribofuranosyl)-; 5-Amino-1-(5-O-phosphono-β-D-ribofuranosyl)-1H-imidazole-4-carboxamide; Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-, 5'-(dihydrogen phosphate); Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-, 5'-phosphate; 5-Amino-1-(5'-phosphofuranoribosyl)-4-imidazolecarboxamide; 5-Amino-1β-D-ribofuranosylimidazole-4-carboxamide 5'-phosphate; 5-Amino-4-imidazolecarboxamide ribonucleoside 5'-monophosphate; 5-Amino-4-imidazolecarboxamide ribonucleotide; 5-Amino-4-imidazolecarboxamide riboside 5'-monophosphate; 5-Amino-4-imidazolecarboxamide ribotide; 5-Aminoimidazole-4-carboxamide ribonucleotide; 5'-Phospho-β-D-ribosyl-5-amino-4-imidazolecarboxamide; 5'-Phosphoribosyl-5-amino-4-imidazolecarboxamide; Acadesine 5'-monophosphate; AICA Ribotide; AICA-Ribonucleotide; AICAR; AICAR monophosphate; AICAR (5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5'-monophosphate); Aminoimidazolecarboxamide ribonucleotide; NSC 283955; NSC 292227; ZMP; ZMP (alarmone). Grade: ≥95%. CAS No. 3031-94-5. Molecular formula: C9H15N4O8P. Mole weight: 338.21.
AICAR (Acadesine)
AICAR (Acadesine, NSC105823, AICA Riboside), an AMPK activator, results in accumulation of ZMP, which mimics the stimulating effect of AMP on AMPK and AMPK kinase. AICAR (Acadesine) induces mitophagy. Phase 3. Group: Inhibitors. Alternative Names: NSC105823, AICA Riboside. CAS No. 2627-69-2. Pack Sizes: 1g. Product ID: S1802. Formula: C9H14N4O5. Smiles: C1=NC(=C(N1C2C(C(C(O2)CO)O)O)N)C(=O)N. Storage Conditions: 2 years -80 in solvent.
United States; Europe
AICA-riboside, 5-phosphate
AICA-riboside, 5-phosphate is AICA riboside with a phosphate group. The functions of AICA riboside include: 1) conversion into AMP mimetic to selectively activate AMPK; 2) competition with adenosine for the uptake of nucleoside transporters, reversible blocking of adenosine reuptake, increasing extracellular adenosine concentration, and indirectly activating adenosine A1 receptors. AICA riboside is involved in metabolic regulation (promoting catabolism and inhibiting anabolism) and adenosine-dependent neuroprotection (inhibiting excitatory synaptic transmission). AICA riboside can be used in the study of metabolic diseases (such as diabetes and obesity) and neurological diseases (such as ischemia and epilepsy), and has central nervous system protective activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AICAR-5'-MP. CAS No. 3031-94-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-134356.
AICAR phosphate
AICAR phosphate, is an AMP-activated protein kinase activator, which is used for the treatment of acute lymphoblastic leukemia and may have applications in treating other disorders such as diabetes. It stimulates glucose uptake and increases the activity of p38 mitogen-activated protein kinases α and β in skeletal muscle tissue, as well as suppressing apoptosis by reducing production of reactive oxygen compounds inside the cell. Synonyms: Acadesine phosphate; AICA Riboside phosphate. Grade: >98%. CAS No. 681006-28-0. Molecular formula: C9H17N4O9P. Mole weight: 356.23.
AICAR phosphate
AICAR phosphate (Acadesine phosphate) is an adenosine analog and a AMPK activator. AICAR phosphate regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR phosphate is also an autophagy, YAP and mitophagy inhibitor[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acadesine phosphate; AICA Riboside phosphate. CAS No. 681006-28-0. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-13417A.
AICAR (Standard)
AICAR (Standard) is the analytical standard of AICAR. This product is intended for research and analytical applications. AICAR (Acadesine) is an adenosine analog and a AMPK activator. AICAR regulates the glucose and lipid metabolism, and inhibits proinflammatory cytokines and iNOS production. AICAR is also an autophagy, YAP and mitophagy inhibitor[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Acadesine (Standard); AICA Riboside (Standard). CAS No. 2627-69-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13417R.
AIDA
AIDA is a selective group I mGluR agonist and could show centrally active following systemic administration in vivo. Uses: Excitatory amino acid antagonists. Synonyms: (RS)-1-Aminoindan-1,5-dicarboxylic acid. Grade: ≥98% by HPLC. CAS No. 168560-79-0. Molecular formula: C11H11NO4. Mole weight: 221.21.
AIDA
AIDA. Group: Biochemicals. Grades: Purified. CAS No. 168560-79-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
A relatively potent and selective antagonist for group I mGlu receptor subtype 1 (pKB = 3.4 for mGlu1a). Complete absence of interacting with on group II or III mGluRs, or ionotropic glutamate receptors. Widely used in studying neural plasticity, learning and memory, and fear conditioning. Centrally active following systemic administration in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 168560-79-0. Pack Sizes: 5mg. Molecular Formula: C??H??NO?. US Biological Life Sciences.
Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 981-15-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Ailanthone
Ailanthone (Δ13-Dehydrochaparrinone) is a potent inhibitor of both full-length androgen receptor (AR) (IC50=69?nM) and constitutively active truncated AR splice variants (AR1-651 IC50=309?nM). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Δ13-Dehydrochaparrinone. CAS No. 981-15-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1943.
a-L-Galactopyranosylamine,6-deoxy-
a-L-Galactopyranosylamine,6-deoxy-. Alternative Names: B-l-fucopyranosylamine, 103419-79-0, KB-48107. CAS No. 103419-79-0. Purity: 96%. Product ID: ACM103419790. Molecular formula: C6H13NO4. Mole weight: 163.17. IUPAC Name: (2R,3S,4R,5S,6S)-2-amino-6-methyloxane-3,4,5-triol. Alfa Chemistry - ISO 9001:32057 Certified.
AIM 100
AIM 100. Group: Biochemicals. Grades: Purified. CAS No. 873305-35-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
AIM-100
AIM-100 is a small molecule inhibitor of Ack1. It not only inhibited Ack1 activation but also suppressed AKT tyrosine phosphorylation, leading to cell cycle arrest in the G1 phase. It could suppress AR Tyr(267) phosphorylation and its recruitment to the ATM enhancer and suppress pTyr267-AR phosphorylation, binding of AR to PSA, NKX3.1, and TMPRSS2 promoters, and inhibit AR transcription activity. Synonyms: AIM-100; AIM 100; AIM100. Grade: >98%. CAS No. 873305-35-2. Molecular formula: C23H21N3O2. Mole weight: 371.43.
AIM-100
AIM-100 is a potent and selective Ack1 inhibitor with an IC50 of 21.58 nM. AIM-100 also inhibits Tyr267 phosphorylation. AIM-100 does not inhibits other kinases including PI3-kinase and AKT subfamily members. AIM-100 has an anticancer effect[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 873305-35-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15290.
AIM4
AIM4 is a compound that can inhibit the aggregation of TDP-43. AIM4 has good biocompatibility and anti-inflammatory activity. AIM4 can be used in the research of diseases such as amyotrophic lateral sclerosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1841140-38-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-172450.
a-Ionone
a-Ionone. Group: Biochemicals. Alternative Names: (3E)-4-(2,6,6-Trimethyl-2-cyclohexen-1-yl)3-buten-2-one; (5E)-Ionone; (E)-4-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-3-buten-2-one. Grades: Highly Purified. CAS No. 127-41-3. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C13H20O. US Biological Life Sciences.
Worldwide
AJ2-30
AJ2-30 is a SLCl5A4 inhibitor. AJ2-30 inhibits endolysosomal TLR7-9-mediated mTOR activation. AJ2-30 blocks endogenous NOD signaling. AJ2-30 can be used in inflammation studies[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2700322-79-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-155864.
AJI-9561
AJI-9561 is a benzoxazole derivative produced by Streptomyces sp. AJ9561. It has cytotoxic activity with IC50 of 0.88 μmol/L and 1.63 μmol/L for Jorkat and P388 cells, respectively. Its mechanism of action is the same as that of UK-1, which can inhibit DNA topoisomerase U. Synonyms: (2,4'-Bibenzoxazole)-4-carboxylic acid, 2'-(2-hydroxy-6-methylphenyl)-. CAS No. 339300-34-4. Molecular formula: C22H14N2O5. Mole weight: 386.36.
Ajmalicine
Ajmalicine (Raubasine) is a potent adrenolytic agent which preferentially blocks α1-adrenoceptor. Ajmalicine is an reversible but non-competitive nicotine receptor full inhibitor, with an IC50 of 72.3 μM. Ajmalicine also can be used as anti-hypertensive, and serpentine, with sedative activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Raubasine. CAS No. 483-04-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N1919.
Ajmaline
An antiarrhythmic agent isolated from Rauwolfia serpentina. Group: Biochemicals. Alternative Names: (17R,21α-Ajmalan-17,21-diol; (+)-Ajmaline; Cardiorythmine; Gilurytmal; Ignazin; Merabitol; NSC 15627; Raugalline; Rauwolfin; Rauwolfine; Rhytmaton; Ritmos; Rytmalin; Siddiqui; Tachmalin; Takycor. Grades: Highly Purified. CAS No. 4360-12-7. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Ajmaline
Ajmaline (Cardiorythmine) is a sodium channel blocking, class 1A anti-arrhythmic agent. Ajmaline blocks HERG currents with an IC50 of 1 μM in HEK cells and 42.3 μM in Xenopus oocytes. Ajmaline can be used for the research of the ventricular tachyarrhythmia[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cardiorythmine; (+)-Ajmaline. CAS No. 4360-12-7. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-B1167.
Ajn I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 55°C in a total reaction volume of 50 μl. Applications: 10 mm tris-hcl (ph 7.5); 100 mm nacl; 0.1 mm edta; 7 mm 2-mercaptoethanol; 200 μg/ml bsa; 50% glycerol. Group: Restriction Enzymes. Purity: 200U; 1000U. ↑CCWGG GGWCC&darr. Activity: 500-3000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Form: Liquid. Source: Acinetobacter johnsonii R2. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1017EN.
Ajoene
Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 92285-01-3. Pack Sizes: 1 mg (21.33 mM * 200 μL in Ethyl acetate). Product ID: HY-106784.
Ajoene
Ajoene is a disulfide that has been found in A. sativum and has antitumor and antiplatelet activities. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Uses: Antiviral agents. Synonyms: (E)-Ajoene; 2-Propenyl-3-(2-propenylsulfinyl)-1-propenyl disulfide. CAS No. 92285-01-3. Molecular formula: C9H14OS3. Mole weight: 234.4.
Ajowan seed oil
Ajowan seed oil. Alternative Names: Trachyspermum ammi seed oil, Oils, ajowan, Carum Copticum Fruit Extract is the extract of the fruit of Carum copticum (L.), Apiaceae. CAS No. 8001-99-8. Product ID: FFC-AR-8001998. Alfa Chemistry - ISO 9001:32057 Certified.
Ajugasterone C
Ajugasterone C. Group: Biochemicals. Grades: Plant Grade. CAS No. 23044-80-6. Pack Sizes: 10mg. Molecular Formula: C27H44O7, Molecular Weight: 480.63. US Biological Life Sciences.
Worldwide
Ajuga Turkestancia P.E. 10% Turkesterone HPLC
Ajuga Turkestancia P.E. 10% Turkesterone HPLC.
CA, FL & NJ
Ajugol
Ajugol is an orally active iridoid glycoside found in the traditional Chinese medicine Leonurus japonicus. Ajugol is an autophagy activator. Ajugol activates TFEB-mediated autophagy and lysosomal biogenesis. Ajugol also has anti-inflammatory effects. Ajugol has great potential in the research of asthma, non-alcoholic fatty liver disease (NAFLD), and osteoarthritis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 52949-83-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0914.
Ajugol (Leonuride )
Ajugol (Leonuride ). Group: Biochemicals. Alternative Names: Ajugol; Leonuride. Grades: Plant Grade. CAS No. 52949-83-4. Pack Sizes: 20mg. Molecular Formula: C15H24O9, Molecular Weight: 348.346. US Biological Life Sciences.
Worldwide
AK-068
AK-068 is a high-affinity and selective STAT6 ligand, with a Ki of 6 nM. AK-068 demonstrates at least >150- and >85-fold binding selectivity over STAT5A (Ki >1 μM) and STAT5B (Ki >500 μM) proteins, respectively. AK-068 is a ligand for target protein for PROTAC, can be used for synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2982851-09-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-169182.
AK-1
AK-1 is a potent, specific and cell-permeable SIRT2 inhibitor (IC50 = 12.5 μM) with excellent selectivity against SIRT1 and SIRT3 (IC50 >50 μM, and >50 μM for SIRT1 and SIRT3 respectively). Synonyms: AK-1; AK 1; AK1; DA-42784; KB-120200; Y1899; J-018989; DA42784; KB120200; J018989; DA 42784; KB 120200; J 018989; 3-(azepan-1-ylsulfonyl)-N-(3-nitrophenyl)benzamide; SIRT2 Inhibitor II, AK-1; SIRT2 Inhibitor II; CHEMBL1797749; 3-(azepan-1-ylsulfonyl)-N-(3-nitrophenyl)benzamide. CAS No. 330461-64-8. Molecular formula: C19H21N3O5S. Mole weight: 403.45.
AK-1690
AK-1690 is a selective PROTAC degrader targeting STAT6 (DC50=1 nM) with a Ki of 6 nM against human STAT6. AK-1690 degrades STAT6 via the interaction of STAT6 with cereblon and a ubiquitin-like process. AK-1690 effectively depletes STAT6 protein in mouse liver and lung tissues, and is applicable to research related to leukemia, Hodgkin's lymphoma, follicular lymphoma, etc.[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2984505-88-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-169179.
AK-2292
AK-2292 is a potent and selective STAT5 PROTAC degrader, with a DC50 of 0.10 μM. AK-2292 induces degradation of STAT5A/B proteins in vitro and in vivo. AK-2292 can induce tumor regression in acute myeloid leukemia and chronic myeloid leukemia xenograft mouse models[1][2]. AK-2292 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2984506-77-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148813.
AK 295
AK 295 (CX 295) is a selective calpain inhibitor. AK 295 can inhibit apoptosis through a calpain-dependent pathway. AK 295 shows potent neuroprotective effect. AK 295 can inhibit the activity of the cysteine protease calpain and reduce myocardial injury. AK 295 can be used for the researches of infection, inflammation, cardiovascular and neurological disease, such as stroke and viral myocarditis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CX 295. CAS No. 160399-35-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119378.
AK 7
AK 7. Group: Biochemicals. Grades: Purified. CAS No. 420831-40-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
AK-7
AK-7 is a selective and brain-permeable SIRT2 inhibitor, which displays no effect on SIRT1 or SIRT3. It could decrease neuronal cholesterol levels and improve motor function and ameliorates brain atrophy in a mouse model of Huntington's disease. Synonyms: AK-7; CS-3223; GL-8955; AK7; CS3223; GL8955; AK 7; CS 3223; GL 8955. Grade: >98%. CAS No. 420831-40-9. Molecular formula: C19H21BrN2O3S. Mole weight: 437.35.
AK-7
AK-7 is a selective cell- and brain-permeable SIRT2 inhibitor, with an IC50 of 15.5 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 420831-40-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16691.
AK-7
Brain-permeable SIRT2 (sirtuin 2) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 420831-40-9. Pack Sizes: 5mg, 25mg. Molecular Formula: C19H21BrN2O3S. US Biological Life Sciences.
Worldwide
AK 7 (N-(3-Bromophenyl)-3-[(hexahydro-1H- azepin-1-yl)sulfonyl]benzamide)
Selective SIRT2 inhibitor (IC50 = 15.5um); displays no effect on SIRT1 or SIRT3. Decreases neuronal cholesterol levels; improves motor function and ameliorates brain atrophy in a mouse model of Huntington's disease. Brain penetrant. Group: Biochemicals. Grades: Highly Purified. CAS No. 420831-40-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
AkaLumine hydrochloride
AkaLumine hydrochloride is a D-luciferin (HY-12591A) analogue with a Km of 2.06 μM for recombinant firefly luciferase (Fluc) protein. AkaLumine hydrochloride emits near-infrared (NIR) light (λmax=677?nm) in reactions with native Fluc. AkaLumine hydrochloride has high tissue-penetration and increases detection sensitivity from deep-tissue targets[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2558205-28-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112641A.
Akardite II
Akardite II (AK-II) is a stabilizer for nitrocellulose (NC) propellants as it scavenges NOx. Akardite II helps control a variety of plant pathogens and weeds, which can be used as fungicides and herbicides[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AK-II. CAS No. 13114-72-2. Pack Sizes: 10 mM * 1 mL in DMSO; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W004643.
Akardit II
Akardit II. Group: Biochemicals. Grades: Highly Purified. CAS No. 13114-72-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
Worldwide
Akarkara P.E. 10:1 (Anacyclus Pyrethrum)
Akarkara P.E. 10:1 (Anacyclus Pyrethrum).
CA, FL & NJ
AKB48-d11
AKB48-d11. Group: Biochemicals. Alternative Names: 1-Pentyl-N-tricyclo[3.3.1.13, 7]dec-1-yl-1H-indazole-3-carboxamide-d11. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C23H20D11N3O, Molecular Weight: 376.58. US Biological Life Sciences.
Worldwide
AKB48 N-Pentanoic Acid
AKB48 N-Pentanoic Acid. Group: Biochemicals. Alternative Names: APINACA N-Pentanoic Acid; 5-(3-((3s,5s,7s)-Adamantan-1-ylcarbamoyl)-1H-indazol-1-yl)pentanoic Acid. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C23H29N3O3, Molecular Weight: 395.49. US Biological Life Sciences.
Worldwide
AKB-6899
AKB-6899, a prolyl hydroxylase domain 3 (PHD3) inhibitor, is a selective HIF-2α stabilizer. AKB-6899 also increases soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages, and has antitumor and antiangiogenic effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1007377-55-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113649.
a-Ketobutyric acid sodium salt 99+%
a-Ketobutyric acid sodium salt 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 2013-26-5. Pack Sizes: 5g, 25g, 100g. US Biological Life Sciences.
Worldwide
a-Ketoglutaric acid disodium salt
a-Ketoglutaric acid disodium salt. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 100g, 250g, 25g, 1Kg, 5Kg. US Biological Life Sciences.
Worldwide
a-Ketoglutaric Acid Disodium Salt Dihydrate
a-Ketoglutaric Acid Disodium Salt Dihydrate. Group: Biochemicals. Alternative Names: 2-Oxoglutaric acid disodium salt; Disodium 2-ketoglutarate. Grades: Highly Purified. CAS No. 305-72-6. Pack Sizes: 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C5H4Na2O5·2H2O, Molecular Weight: 226.09. US Biological Life Sciences.
Worldwide
a-Ketoglutaric acid disodium salt dihydrate 99+%
a-Ketoglutaric acid disodium salt dihydrate 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg, 5Kg. US Biological Life Sciences.
Worldwide
a-Ketoglutaric acid potassium salt
a-Ketoglutaric acid potassium salt. Group: Biochemicals. Alternative Names: 2-Oxopentanedioic acid potassium salt; Potassium hydrogen 2-ketoglutarate. Grades: Highly Purified. CAS No. 997-43-3. Pack Sizes: 25g, 50g, 100g. Molecular Formula: C?H?O?K, Molecular Weight: 184.19. US Biological Life Sciences.
Worldwide
AKI-001
AKI-001 is a potent Aurora kinase inhibitor, which exhibits low nanomolar potency against both Aurora A and Aurora B enzymes, excellent cellular potency (IC50 < 100 nM), and good oral bioavailability. Synonyms: AKI-001; AKI 001; AKI001. Grade:>98%. CAS No. 925218-37-7. Molecular formula: C21H24N4O. Mole weight: 348.45.
AKI603
AKI603 is an inhibitor of Aurora kinase A (AurA) with IC50 of 12.3 nM. It can induce senescence in chronic myeloid leukemia cells carrying the T315I mutation. AKI603 shows strong anti-proliferative activity in leukemia cells. Synonyms: AKI-603. Grade: 98%. CAS No. 1432515-73-5. Molecular formula: C19H23N9O2. Mole weight: 409.4.
A-kinase anchor protein 9 (1398-1407)
A-kinase anchor protein 9 (1398-1407) is amino acids 1398 to 1407 fragment of A-kinase anchor protein 9. AKAP-9 is a scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. Synonyms: AKAP-9 (1398-1407).