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| Product | Description | |
|---|---|---|
| Agomelatine Impurity A | Agomelatine Impurity A is an impurity originating from the renowned Agomelatine, a notable depression-alleviating medication. CAS No. 32820-10-3. Molecular formula: C11H14O2. |  |
| Agomelatine Impurity B | An analogue of Agomelatine. Synonyms: 2-(7-Methoxynaphthalen-1-yl)acetamide. Grade: > 95%. CAS No. 138113-07-2. Molecular formula: C13H13NO2. Mole weight: 215.25. | |
| Agomelatine Impurity D | An analogue of Agomelatine. Synonyms: N-Acetyl-N-[2-(7-methoxy-1-naphthalenyl)ethyl]acetamide. Grade: > 95%. CAS No. 1379005-34-1. Molecular formula: C17H19NO3. Mole weight: 285.35. | |
| Agomelatine Impurity II | An analogue of Agomelatine. Synonyms: Agomelatine Dimer Urea. Grade: > 95%. CAS No. 185421-27-6. Molecular formula: C27H28N2O3. Mole weight: 428.54. | |
| Agomelatine (S20098, N-[2-(7-Methoxynaphth-1-yl)ethyl]acetamide) | A melatoninergic agonist and selective an. Group: Biochemicals. Alternative Names: S20098, N-[2-(7-Methoxynaphth-1-yl)ethyl]acetamide. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Agomelatine (Standard) | Agomelatine (Standard) is the analytical standard of Agomelatine. This product is intended for research and analytical applications. Agomelatine (S-20098) is a specific agonist of MT1 and MT2 receptors with Kis of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively[1]. Agomelatine is a selective 5-HT2C receptor antagonist with pKis of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S-20098 (Standard). CAS No. 138112-76-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17038R. |  |
| Agonodepside B | Agonodepside B is a fungal metabolite produced by the strain of the endophytic fungus F7524. Synonyms: benzoic acid, 4-[[2,4-dihydroxy-3-methyl-6-[(1E)-1-methyl-1-propenyl]benzoyl]oxy]-2-hydroxy-3-methyl-6-[(1E)-1-methyl-1-propenyl]-. Grade: >95%. CAS No. 445298-41-9. Molecular formula: C24H26O7. Mole weight: 426.46. | |
| Agouti-related Protein (AGRP) (25-82), human | Agouti-related protein (AgRP) is a neuropeptide produced in the brain by the AgRP/NPY neuron. It acts as a melanocortin receptor antagonist that exerts a central inhibitory action on the Hypothalamic-Pituitary-Thyroid (HPT) Axis. Grade: 95%. Molecular formula: C279H468N80O90S1. Mole weight: 6415.39. | |
| AGPS-IN-1 | AGPS-IN-1 (Compound 2i) is an effective AGPS binder. AGPS-IN-1 reduces ether lipids levels and cell migration rate. AGPS-IN-1 inhibits epithelial-mesenchymal transition (EMT) in prostate PC-3 and breast MDA-MB-231 cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2316782-88-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-153910. | |
| AGPTNA Chain A, Pcbp2 Kh1-Kh2 Domains (38-58) | AGPTNA Chain A, Pcbp2 Kh1-Kh2 Domains (38-58). | |
| Agricultural |  | |
| Agrimol B | Agrimol B, a polyphenol, is an orally active and potent SIRT1 activator. Agrimol B shows anti-adipogenic and anticancer activity. Agrimol B shows antibacterial activity against plant pathogens. Agrimol B dramatically inhibits 3T3-L1 adipocyte differentiation by reducing PPARγ, C/EBPα, FAS, UCP-1, and apoE expression. The action of Agrimol B on the cancer cells is likely derived from its effect on c-MYC, SKP2 and p27[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 55576-66-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0704. | |
| Agrimonolide | Agrimonolide isolated from the herb of Agrimonia pilosa Ledeb. Synonyms: (S)-3,4-Dihydro-6,8-dihydroxy-3-[2-(4-methoxyphenyl)ethyl]-1H-2-benzopyran-1-one; (3S)-6,8-Dihydroxy-3-[2-(4-methoxyphenyl)ethyl]-3,4-dihydro-1H-is ochromen-1-one. Grade: 98.5%. CAS No. 21499-24-1. Molecular formula: C18H18O5. Mole weight: 314.3. | |
| Agrimonolide 6-O-glucoside | Agrimonolide 6-O-glucoside is isolated from the herbs of Agrimonia pilosa. Synonyms: Agrimonolide-6-O-glucopyranoside. Grade: 98.5%. CAS No. 126223-29-8. Molecular formula: C24H28O10. Mole weight: 476.5. | |
| Agrimony Extract | Agrimony (Agrimonia eupatoria) leaf extract, 20% in water-glycerin, provides astringent, toning, and blemish-clearing effects. Product ID: CI-SC-0850. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| AGRION C-100 Ion Exchange Resins | AGRION C-100 Ion Exchange Resins. CAS No. 69011-20-7. Molecular formula: C28H30. Mole weight: 366.5g/mol. IUPAC Name: 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene. SMILES: CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1.C=CC1=CC=CC=C1C=C. InChI: InChI=1S/C10H12.C10H10.C8H8/c2*1-3-9-7-5-6-8-10(9)4-2;1-2-8-6-4-3-5-7-8/h3,5-8H,1,4H2,2H3;3-8H,1-2H2;2-7H,1H2. |  |
| Agrobactin | It is produced by the strain of Agrobacterium tume faciens. It's a ferric ion carrier. Synonyms: Ferriagrobactin; N-(3-(2,3-Dihydroxybenzamido)propyl)-N-(4-(2,3- dihydroxybenzamido)butyl)-2-(2,3-dihydroxyphenyl)- trans-5-methyl-oxazoline-4-carboxamide; 4-Oxazolecarboxamide, N-(4-((2,3-dihydroxybenzoyl)amino)butyl)-N-(3-((2,3-dihydroxybenzoyl)amino)propyl)-2-(2,3-dihydroxyphenyl)-4,5-dihydro-5-methyl-, (4S-trans)-; (2Z,4S,5R)-N-[4-[(2,3-dihydroxybenzoyl)amino]butyl]-N-[3-[(2,3-dihydroxybenzoyl)amino]propyl]-2-(5-hydroxy-6-oxocyclohexa-2,4-dien-1-ylidene)-5-methyl-1,3-oxazolidine-4-carboxamide; L-Agrobactin. Grade: 95%. CAS No. 70393-50-9. Molecular formula: C32H36N4O10. Mole weight: 636.65. | |
| Agrochelin | It is produced by the strain of Agrobacterium sp. ALET-304. The IC50 of soil bactericin against P-388 was 0.053 ?ol/L, and the IC50 of cell a1-549, HT-29 and MEL 38 was between 0.107-0.268 ?ol/L. Synonyms: (3S)-3-hydroxy-3-{(2S,4R)-2-[(4R)-2-(2-hydroxy-6-pentylphenyl)-4,5-dihydro-1,3-thiazol-4-yl]-3-methyl-1,3-thiazolidin-4-yl}-2,2-dimethylpropanoic acid; CHEBI:65375; Q27133819. Molecular formula: C23H34N2O4S2. Mole weight: 466.66. | |
| Agrocin 84 | It is produced by the strain of Agrobacterium radiobacter. It can inhibit DNA synthesis, and sterilize Agrobacterium Tume Faciens. Synonyms: Agrocin; D-Glucofuranose,1-[hydrogen[9-[3-deoxy-5-O-[[(4,5-dideoxy-4-methyl-D-threo-pentonoyl)amino]hydroxyphosphinyl]-b-D-threo-pentofuranosyl]-9H-purin-6-yl]phosphoramidate]; Mono-D-glucofuranosyl[9-[3-deoxy-5-O-[[(4,5-dideoxy-4-methyl-D-threo-pentonoyl)amino]hydroxyphosphinyl]-b-D-threo-pentofuranosyl]-9H-purin-6-yl]phosphoramidate. CAS No. 59111-78-3. Molecular formula: C22H36N6O16P2. Mole weight: 702.50. | |
| agroclavine dehydrogenase | The enzyme participates in the biosynthesis of ergotamine, an ergot alkaloid produced by some fungi of the Clavicipitaceae family. The reaction is catalysed in the opposite direction to that shown. The substrate for the enzyme is an iminium intermediate that is formed spontaneously from chanoclavine-I aldehyde in the presence of glutathione. Group: Enzymes. Synonyms: easG (gene name). Enzyme Commission Number: EC 1.5.1.46. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1527; agroclavine dehydrogenase; EC 1.5.1.46; easG (gene name). Cat No: EXWM-1527. |  |
| Agrocybin | It is produced by the strain of Agrocybe dura. It has the activity of anti-gram-positive bacteria, negative bacteria, mycobacterium and mildew, which is unstable and easy to be inactivated. Synonyms: 8-Hydroxy-2,4,6-octatriynamide; A0AFV4JUIT; NSC636326; BRN 1761957; 2,4,6-OCTATRIYNAMIDE, 8-HYDROXY-; SCHEMBL1654320; CHEMBL1967731; CTK8J1637; DTXSID20202786; ZINC5722724; LMFA08010027; AKOS006341004; NSC-63632. Grade: 97%. CAS No. 544-44-5. Molecular formula: C8H5NO2. Mole weight: 147.13. | |
| Agrocybin (1-15) | Agrocybin is an antimicrobial peptide produced by Agrocybe cylindracea (Toadstool). It has antibacterial, antifungal and antiviral activity. Synonyms: Ala-Asn-Asp-Pro-Gln-Cys-Leu-Tyr-Gly-Asn-Val-Ala-Ala-Lys-Phe. Grade: ≥96%. Molecular formula: C71H107N19O22S. Mole weight: 1610.80. | |
| Agrumen Aldehyde Light | Agrumen Aldehyde Light. CAS No. MIXTURE. VIGON Item # 502451. Categories: Speciality Ingredients Suppliers, Fragrances, Perfumers. |  America & Internationally |
| Ags I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme 90% of dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. TTS↑AA AA↓STT. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Form: Liquid. Source: Agrococcus species 25. Pack: 10 mM Tris-HCl(pH 7.5); 100 mM KCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA, 50% glycerol. Cat No: RE-1015EN. | |
| Ag SiO2 core shell Nanoparticle | Ag SiO2 core shell Nanoparticle. Mole weight: 275.8207 g/mol. Purity: 99.9%. | |
| Ag-Sn Alloy Nanoparticles/Nanoparticles | Ag-Sn Alloy Nanoparticles/Nanoparticles. Mole weight: 226.5782 g/mol. Purity: 99.9%. | |
| Ag-Sn Alloy Powder | Sn-Ag alloy powder is a binary alloy powder of tin and silver, which is a low temperature brazing material. Purity: Ag basis 99.99%. | |
| Aguaje Fruit Powder (Mauritia Flexuosa) | Aguaje Fruit Powder (Mauritia Flexuosa). |  CA, FL & NJ |
| AGX51 | AGX51 is the first-in-class pan-Id (inhibitors of DNA-binding/differentiation proteins) antagonist and degrader. AGX51 inhibits Id1-E47 interaction, leading to ubiquitin-mediated degradation of Ids, cell growth arrest, and viability reduction. AGX51 can inhibit TNBC and has an IC50 of about 25 nM. AGX51 can be used in cancer research. Uses: Scientific research. Category: Signaling pathways. CAS No. 330834-54-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129241. | |
| AH 001 | AH 001 is a potent melatonin agonist. Synonyms: AH 001; AH001; AH-001; 8-Methoxy-2-acetamidotetralin; N-(8-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide. Grade: 98%. CAS No. 80270-68-4. Molecular formula: C13H17NO2. Mole weight: 219.28. | |
| AH078 | AH078 is a PROTAC-based CK1δ/ε degrader (DC50=0.55 μM, Dmax=70%) that lacks subtype selectivity between CK1δ and CK1ε. AH078 induces target protein degradation either by recruiting the CUL4-CRBN E3 ligase complex and proteasome, or via the VHL- and ubiquitin-dependent pathway. AH078 also exhibits selectivity for CK1α, and is widely applicable to research related to colon cancer, pancreatic cancer, breast cancer, ovarian cancer, chronic lymphocytic leukemia, acute myeloid leukemia, glioma, and metastatic breast adenocarcinoma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3110370-06-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-170859. | |
| AH1 | AH1 is an immunodominant MHC class I-restricted nonamer peptide recognized by CD8+ cytotoxic T lymphocytes. AH1 derives from the envelope protein (gp70) of an endogenous ecotropic murine leukemia virus and is presented by the MHC class I Ld molecule. AH1 can be used for the research of colorectal carcinoma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 181272-91-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4193. | |
| AH 11110 hydrochloride | The hydrochloride salt form of AH 11110, which is an α1B-adrenoceptor ligand and has been found to exhibit interaction with α1-adrenoceptors as well as α2-adrenoceptors. Synonyms: AH 11110 hydrochloride; AH11110 hydrochloride; AH-11110 hydrochloride; 4-Imino-1-(2-phenylphenoxy)-4-piperidinebutan-2-ol hydrochloride. Grade: ≥98% by HPLC. CAS No. 179388-65-9. Molecular formula: C21H26N2O2.HCl. Mole weight: 374.91. | |
| AH 11110 hydrochloride | AH 11110 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 179388-65-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AH-1763 IIa | AH-1763 la is an antibiotic produced by Streptomyces cyaneus against herpes virus. Its ED50 against herpes simplex virus type 1 (HSV-1) is 2.1 μg/mL, and its IC50 against Vero cells is 15.2 μg/mL. Molecular formula: C22H18O6. Mole weight: 378.37. | |
| AH1 Sequence (6-14) | AH1 Sequence (6-14) is the H2-Ld-restricted epitope derived from gp-70, which is expressed in CT26 (colon carcinoma cells) and numerous other tumor cell lines. Synonyms: H-Ser-Pro-Ser-Tyr-Val-Tyr-His-Gln-Phe-OH. Molecular formula: C54H70N12O15. Mole weight: 1127.3. | |
| AH2-14c | AH2-14c is an inhibitor for DNA demethylase ALKBH2. AH2-14c inhibits the cell viability (IC50 is 4.56 μM) and migration of GBM U87. AH2-14c regulates the expression of apoptosis-related genes, and induces apoptosis in GBM U87 cell[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3099231-05-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-168708. | |
| AH 23848 calcium salt | AH-23848 is a dual antagonist of TP1 and EP4 receptors. Uses: Anti-arrhythmia agents. Synonyms: AH23848; (Z)-7-[(1R,2R,5S)-2-morpholin-4-yl-3-oxo-5-[(4-phenylphenyl)methoxy]cyclopentyl]hept-4-enoic acid; 81496-19-7; AH 23848; AH-23848; AH-23848B; (-)AH23848; (-)-AH23848; GTPL1949; SCHEMBL3488581; CHEBI:90389; 81443-73-4; (1R,2R,5S)-AH23848; (-)-AH 23848; Q27074357; (4Z)-7-[(1R,2R,5S)-5-[([1,1'-biphenyl]-4-yl)methoxy]-2-(morpholin-4-yl)-3-oxocyclopentyl]hept-4-enoic acid; Rel-(Z)-7-((1R,2R,5S)-5-([1,1'-biphenyl]-4-ylmethoxy)-2-morpholino-3-oxocyclopentyl)hept-4-enoic acid. Grade: ≥90%. CAS No. 81496-19-7. Molecular formula: C29H34NO5·1/2Ca. Mole weight: 993.2. | |
| AH3960 | AH3960 is an agonist of parathyroid hormone receptor-1 (PTHR1). Synonyms: Trione; AH 3960; AH-3960; 2,4,6(1H,3H,5H)-Pyrimidinetrione, 1,3-dibutyl-5-(diaminomethylene)-; 1,3-Dibutyl-5-(diaminomethylene)-2,4,6(1H,3H,5H)-pyrimidinetrione; 1,3-dibutyl-6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboximidamide. Grade: >98%. CAS No. 862907-48-0. Molecular formula: C13H22N4O3. Mole weight: 282.34. | |
| AH3960 | AH3960 (compound 16c) is an antagonist of androgen receptor. AH3960 binds wild as well as T877 mutant type androgen receptors. AH3960 selectively inhibits T877 with an IC50 value of 0.82 μM. AH3960 also serves as an agonist of parathyroid hormone receptor-1 (PTHR1)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 862907-48-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15103. | |
| AH 6809 | AH 6809 is an antagonist of EP and DP receptor, with Kis of 1217, 1150, 1597, and 1415 nM for the cloned human EP1, EP2, EP3-III, and DP receptor respectively. AH 6809 has a Ki of 350 nM for mouse EP2 receptor[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 33458-93-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10418. | |
| AH 6809 | AH 6809 is an EP1 (pA2 = 6.8) and EP2 (Ki = 350 nM) receptor antagonist. Uses: An ep and dp receptor antagonist with nearly equal affinity for the cloned human ep1, ep2, ep3-iii, and dp1 receptors. Synonyms: AH 6809; AH6809; AH-6809; 6-isopropoxy-9-oxoxanthene-2-carboxylic acid. Grade: ≥95.0%. CAS No. 33458-93-4. Molecular formula: C17H14O5. Mole weight: 298.29. | |
| AH 6809 | AH 6809. Group: Biochemicals. Grades: Purified. CAS No. 33458-93-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AH 7614 | AH 7614 is a FFA4/GPR120 antagonist and has been found to exhibit effects in restraining intracellular calcium accumulation induced by either linoleic acid or a FFAR4 agonist. Synonyms: AH 7614; AH7614; AH-7614; 4-Methyl-N-9H-xanthen-9-yl-benzenesulfonamide. Grade: ≥98% by HPLC. CAS No. 6326-6-3. Molecular formula: C20H17NO3S. Mole weight: 351.42. | |
| AH-7614 | AH-7614 is a potent and selective FFA4 (GPR120) antagonist, with pIC50s of 7.1, 8.1, and 8.1 for human, mouse, and rat FFA4, respectively. AH-7614 has selectivity for FFA4 over FFA1 (pIC50<4.6). AH-7614 is able to block effects of both the polyunsaturated ω-6 fatty acid linoleic acid and the synthetic FFA4 agonist[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6326-6-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19996. | |
| Ah-AMP1 | Ah-AMP1 is an antimicrobial peptide and a plant defensin produced by Aesculus hippocastanum (Horse chestnut). It has antifungal activity. Synonyms: Aesculus hippocastanum antimicrobial protein 1; Leu-Cys-Asn-Glu-Arg-Pro-Ser-Gln-Thr-Trp-Ser-Gly-Asn-Cys-Gly-Asn-Thr-Ala-His-Cys-Asp-Lys-Gln-Cys-Gln-Asp-Trp-Glu-Lys-Ala-Ser-His-Gly-Ala-Cys-His-Lys-Arg-Glu-Asn-His-Trp-Lys-Cys-Phe-Cys-Tyr-Phe-Asn-Cys (Disulfide bridge: Cys2-Cys50, Cys14-Cys35, Cys20-Cys44, Cys24-Cys46). Grade: >98%. CAS No. 169027-67-2. Molecular formula: C245H347N79O75S8. Mole weight: 5855.43. | |
| AHD-[2,4,5-13C3] | AHD-[2,4,5-13C3] is the labelled analogue of AHD, which is a metabolite of Nitrofuran. Synonyms: 1-Amino-imidazolidin-2,4-dione-[2,4,5-13C3]; AHD-13C3; 1-Amino-2,4-imidazolidinedione-13C3; 1-Aminoimidazolidin-2,4-dione-13C3; AHD-13C3; 1-Amino Hydantoin-13C3. Grade: 95% by HPLC; 98% atom 13C. CAS No. 957509-31-8. Molecular formula: [13C]3H5N3O2. Mole weight: 118.07. | |
| AHK-Cu | AHK-Cu. CAS No. 682809-81-0. Product ID: CDC10-0607. Molecular formula: C15H24ClCuN6O4. Category: Cosmetic Active Peptide. Product Keywords: Cosmetic Ingredients; Active Ingredients; Cosmetic active peptide; AHK-Cu; CDC10-0607; Cosmetic active peptide; C15H24ClCuN6O4; Cosmetic Peptide; 682809-81-0. Appearance: Blue powder. Purity: 98%/99%. Application: Anti-Wrinkle and anti-aging. |  |
| AHK-Cu(1:1) | AHK-Cu(1:1). CAS No. 682809-81-0. Product ID: CDC10-0667. Category: Cosmetic Active Peptide. Product Keywords: Cosmetic Ingredients; Active Ingredients; Cosmetic Active Peptide; ; CDC10-0667; AHK-Cu(1:1); Cosmetic Active Peptide; ; 682809-81-0. Purity: 98%/99%. Applications: Anti-Wrinkle and anti-aging. | |
| AHK Tripeptide-3 | AHK Tripeptide-3 is a 3-amino acid that exhibits activity in hair growth, healing wounds and wound regeneration. Synonyms: Ala-His-Lys; L-alanyl-L-histidyl-L-lysine; alanylhistidyllysine. Grade: 98%. CAS No. 126828-32-8. Molecular formula: C15H26N6O4. Mole weight: 354.41. | |
| Ahl I | One unit of the enzyme is the amount required to hydrolyze 1 μg of T7 DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 90% of t7 dna fragments can be ligated and recut. Group: Restriction Enzymes. A↑CTAGT TGATC↓A. Appearance: 10 X SE-buffer B, BSA. Storage: -20°C. Form: Liquid. Source: Alteromonas haloplanktis SP. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: RE-1016EN. | |
| a-Homonojirimycin | a-Homonojirimycin is a inhibitor of the enzymatic compound called glucosidase used for studying lysosomal storage diseases like Gaucher disease and Pompe disease. Synonyms: α-HNJ; (2R,3R,4R,5S,6R)-2,6-β(dihydroxymethyl)piperidine-3,4,5-triol; α-Homonojirimycin; 3,4,5-Piperidinetriol, 2,6-bis(hydroxymethyl)-, [2R-(2α,3α,4β,5α,6β)]-; (2R,3R,4R,5S,6R)-2,6-Bis(hydroxymethyl)-3,4,5-piperidinetriol; 2,6-Dideoxy-2,6-imino-D-glycero-L-gulo-heptitol; Homonojirimycin; 3,4,5-Piperidinetriol, 2,6-bis(hydroxymethyl)-, (2α,3α,4β,5α,6β)-. Grade: ≥98%. CAS No. 119557-99-2. Molecular formula: C7H15NO5. Mole weight: 193.20. | |
| AhR Agonist V, VAF347 | A cell-permeable pyrimidinylphenylamine compound that directly and reversibly targets aryl hydrocarbon receptor (AhR) with high-affinity, and induces AhR signaling. Reported to act as an immunomodulator with anti-inflammatory properties. Potently suppresses IgE secretion in B-cells with an IC50 of ~2nM, and inhibits dendritic cells-mediated T-cell proliferation and cytokine production. Further, decreases lung eosinophilia in B-cell-deficient mice, and allergic inflammation. Downregulates PU.1 transcription factor, and impairs human monocytes and Langerhans dendritic cells differentiation. Group: Biochemicals. Alternative Names: ((4-(3-Chloro-phenyl)-pyrimidin-2-yl)-(4-trifluoromethyl-phenyl)-amine). Grades: Highly Purified. CAS No. 574759-62-9. Pack Sizes: 10mg. Molecular Formula: C??H??ClF?N?, Molecular Weight: 349.7. US Biological Life Sciences. | Worldwide |
| AHR antagonist 2 | AHR antagonist 2 is a potent aryl hydrocarbon receptor (AHR) antagonist, extracted from patent WO2019101641A1, compound example 1. Synonyms: AHR antagonist 2; 2338747-54-7; SCHEMBL21001701; CSSGBPKFVJOAIZ-LBPRGKRZSA-N; AKOS040732400; MS-27306; HY-135831; CS-0114332; N-[(2S)-1-hydroxypropan-2-yl]-2-pyridin-3-yl-6-[4-(trifluoromethoxy)phenyl]pyrimidine-4-carboxamide. Grade: 99%. CAS No. 2338747-54-7. Molecular formula: C20H17F3N4O3. Mole weight: 418.37. | |
| AHR antagonist 4 | AHR antagonist 4 is a potent aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1 (example 293; IC50 = 82.2 nM). It has anti-cancer effects. CAS No. 2242465-58-1. Molecular formula: C20H14F6N4O4. Mole weight: 488.34. | |
| AHR Antagonist 5 | AHR Antagonist 5, an effective and orally active aromatic hydrocarbon receptor (AHR) antagonist with IC50 of less than 0.5 μM. It can significantly inhibit tumor growth in combination with the checkpoint inhibitor anti-PD-1. Synonyms: BCP33104; HY-136220; CS-0120848; (R)-N-(2-(5-Fluoropyridin-3-Yl)-8-Isopropylpyrazolo[1,5-A][1,3,5]Triazin-4-Yl)-2,3,4,9-Tetrahydro-1H-Carbazol-3-Amine Trihydrochloride. Grade: ≥98% by HPLC. CAS No. 2247953-39-3. Molecular formula: C25H27Cl3FN7. Mole weight: 550.9. | |
| AHR antagonist 5 free base | AHR antagonist 5 free base, a selective and orally active aryl hydrocarbon receptor (AHR) inhibitor, effectively blocks AHR from translocating from the cytoplasm to the nucleus. AHR antagonist 5 free base is highly selective for AHR over other receptors, transporters, and kinases. CAS No. 2247950-42-9. Molecular formula: C25H24FN7. Mole weight: 441.50. | |
| AHR antagonist 5 hemimaleate | AHR antagonist 5 hemimaleate is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist with an IC50 of < 0.5 μΜ. AHR antagonist 5 hemimaleate significantly inhibits tumor growth combined with checkpoint inhibitor anti-PD-1. Molecular formula: C29H28FN7O4. Mole weight: 499.55. | |
| AhR Antagonist III, GNF351 (N-(2-(3H-Indol-3-yl)ethyl)-9-isopropyl-2-(5-methyl-3-pyridyl)-7H-purin-6-amine, N-(2-(1H-Indol-3-yl)ethyl)-9-isopropyl-2-(5-methylpyridin-3-yl)-9H-purin-6-amine) | A cell-permeable purine compound that acts as a high-affinity aryl hydrocarbon receptor (AhR) antagonist (IC50 = 62nM in mouse liver cytosol expressing humanized AhR) and lacks any agonist activity even at higher doses. Reportedly binds with high affinity to the ligand-binding pocket of AhR and blocks the binding of an array of exogenous and endogenous ligands. Shown to non-covalently interact with Ser317, His291, and Ser365 in human and with Ser311, His285, and Ser359 in mouse AhR. Represses AhR transcriptional activity via the dioxin response element (DRE)-dependent and independent mediated responses in human and mouse cells (IC50 = 8.5nM in HepG2 40/6 cells). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| AhR modulator-1 | AhR modulator-1 is a selective and orally active aryl hydrocarbon receptor (AhR) modulator with anti-estrogenic properties in rat uterus. It inhibits metastasis in part by inhibiting prostatic VEGF production prior to tumor formation. Synonyms: 6-Methyl-1,3,8-trichlorodibenzofuran; MCDF; 6-MCDF; Dibenzofuran, 6-methyl-1,3,8-trichloro-; 1,3,8-Trichloro-6-methyldibenzo[b,d]furan. Grade: ≥90%. CAS No. 118174-38-2. Molecular formula: C13H7Cl3O. Mole weight: 285.55. | |
| AHT Acid/Alkali Resistance Membrane | AHT Acid/Alkali Resistance Membrane. Product ID: ACIR-HP005. Alfa Chemistry - ISO 9001:32057 Certified. | |
| AHU-377 hemicalcium salt | LCZ696 is a novel single molecule comprising molecular moieties of valsartan and NEP inhibitor prodrug AHU377 (1:1 ratio). Oral administration of LCZ696 caused dose-dependent increases in atrial natriuretic peptide immunoreactivity (due to NEP inhibition) in Sprague-Dawley rats and provided sustained, dose-dependent blood pressure reductions in hypertensive double-transgenic rats. In healthy participants, a randomized, double-blind, placebo-controlled study (n = 80) of single-dose (200-1200 mg) and multiple-dose (50-900 mg once daily for 14 days) oral administration of LCZ696 showed that peak plasma concentrations were reached rapidly for valsartan (1.6-4.9 hours), AHU377 (0.5-1.1 hours), and its active moiety, LBQ657 (1.8-3.5 hours). LCZ696 is superior to valsartan alone in reducing blood pressure. Preliminary results from a Phase II trial showed that LCZ696 reduced NT-proBNP to a greater extent than valsartan alone, and in addition LCZ696 had beneficial effects on symptoms. Synonyms: calcium 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate; AHU337; AHU-337; AHU 337; LCZ696; LCZ 696; LCZ696; Sacubitril. Grade: >98%. CAS No. 1369773-39-6. Molecular formula: C24H28NO5-. Mole weight: 410.48. | |
| a-Hydroxyisobutyric acid 98+% (GC) | a-Hydroxyisobutyric acid 98+% (GC). Group: Biochemicals. Grades: GC. Pack Sizes: 25g, 100g, 250g, 1Kg, 5Kg. US Biological Life Sciences. | Worldwide |
| A-Hydroxyisocaproic Acid Calcium (HICA) | A-Hydroxyisocaproic Acid Calcium (HICA). | CA, FL & NJ |
| A-HYDROXY PHENYBUTYRIC ACID | A-HYDROXY PHENYBUTYRIC ACID. CAS No. 111611-91-7. Product ID: ACM111611917. Alfa Chemistry - ISO 9001:32057 Certified. | |
| a-Hydroxytamoxifen (trans- (Z) -1-[4-[2- (Dimethylamino) ethoxy]phenyl]-1, 2-diphenyl-1-butene-3-ol) | A metabolite of the chemotherapeutic drug tamoxifen. Exhibits a more potent estrogen agonist/antagonist activity than the parent drug. Also active as an intramembranous inhibitor of lipid peroxidation. Group: Biochemicals. Alternative Names: trans- (Z) -1-[4-[2- (Dimethylamino) ethoxy]phenyl]-1, 2-diphenyl-1-butene-3-ol. Grades: Highly Purified. CAS No. 97151-02-5Mol. Formula: »C26H29 NO2MoreDetails»Order». Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| AI-10-104 | AI-10-104 is an inhibitor for runt-related transcription factor (RUNX), which enhances the cytotoxicity in myeloma cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1881276-00-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122657. | |
| AI-10-49 | AI-10-49 is a protein-protein interaction inhibitor that selectively binds to CBFβ-SMMHC and disrupts its binding to RUNX1 with a FRET IC50 of 0.26 uM. Synonyms: AI-10-49; AI 10-49; AI10-49; AI-1049; AI 1049; AI1049. Grade: >98%. CAS No. 1256094-72-0. Molecular formula: C30H22F6N6O5. Mole weight: 660.52. | |
| AI-10-49 | AI-10-49 is an inhibitor of leukemic oncoprotein CBFβ-SMHHC. AI-10-49 inhibits the binding of CBFβ-SMMHCto the RUNX1 Runt domain with IC50 value of 0.26 μM. AI-10-49 can be used for the research of leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1256094-72-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16786. | |
| AI-3 | AI-3 is an antioxidant response element activator and could probably be useful in studies of oxidative stress related diseases. Synonyms: AI-3; AI 3; AI3; 1-Chloro-6,7-dihydro-6,6-dimethyl-3-(methylsulfonyl)-benzo[c]thiophen-4(5H)-one. Grade: ≥98% by HPLC. CAS No. 882288-28-0. Molecular formula: C11H13ClO3S2. Mole weight: 292.80. | |
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