A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the suppliers website for prices or more information.
| Product | Description | |
|---|---|---|
| Aftin-5 ((2R)-2-[[9-Isopropyl-6-(N-methylanilino)purin-2-yl]amino]butan-1-ol, Amyloidbeta Forty-Two Inducer 5) | Roscovitine-related purine with no activity on CDKs (used as control for roscovitine). Selectively and potently increases production of extracellular Ab42 and decreases production of extracellular Ab38 in cultured cells. Extracellular Ab40 levels remain stable. Intracellular levels of these amyloids appear to remain stable. Alzheimer's Disease (AD) accelerator that interacts with VDAC1, prohibitin and mitofilin, possibly interfering with subcellular compartmentalization and lipid rafts properties, shifting gamma-secretase activity toward Ab42 generation. Induces a reversible mitochondrial phenotype reminiscent of the one observed in AD brains. Tool to detect inhibitors of Aftin-induced actions (potential anti-AD compounds). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences. |  Worldwide |
| Aftobetin Hydrochloride | Aftobetin, also known as ANCA11 and NCE-11, is a novel amyloid-binding compound applied topically in the form of an ophthalmic ointment. Aftobetin may be of useful as an aid in the diagnosis Alzheimer's disease. Synonyms: Aftobetin Hydrochloride; NCE-11; Aftobetin Hydrochloride [USAN]; UNII-A1FCZ940WA; 1353222-83-9; A1FCZ940WA; 11-HCl; 2-Propenoic acid, 2-cyano-3-(6-(1-piperidinyl)-2-naphthalenyl)-, 2-(2-(2-methoxyethoxy)ethoxy)ethyl ester, hydrochloride (1:1), (2E)-; Aftobetin hydrochloride (USAN); 2-(2-(2-Methoxyethoxy)ethoxy)ethyl (2E)-2-cyano-3-(6-(piperidin-1-yl)naphthalen-2-yl)prop-2-enoate monohydrochloride; Aftobetin HCl; 2-[2-(2-Methoxyethoxy)ethoxy]ethyl (2E)-2-cyano-3-[6-(piperidin-1-yl)naphthalen-2-yl]prop-2-enoate monohydrochloride; aftobetin-hydrochloride; ANCA-11 HYDROCHLORIDE; CHEMBL2364602; DTXSID90159314; AKOS040750170; AFTOBETIN HYDROCHLORIDE [WHO-DD]; D10607; Q27273497. CAS No. 1353222-83-9. Molecular formula: C26H33ClN2O5. Mole weight: 489.009. |  |
| Afuresertib | Afuresertib, also known as GSK2110183, is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GSK2110183 binds to and inhibits the activity of Akt, which may result in inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents. Synonyms: GSK-2110183; GSK 2110183; GSK2110183; GSK-2110183B; GSK 2110183B; GSK2110183B. Grade: 98%. CAS No. 1047644-62-1. Molecular formula: C18H17Cl2FN4OS. Mole weight: 427.32. | |
| Afuresertib | Afuresertib (GSK2110183) is an orally bioavailable, selective, ATP-competitive and potent pan-Akt kinase inhibitor with Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GSK2110183; LAE002. CAS No. 1047644-62-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15727. |  |
| Afuresertib HCl | Afuresertib HCl is a potent pan-AKT inhibitor. Synonyms: N-((S)-1-amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide hydrochloride; GSK2110183; GSK 2110183; GSK-2110183; GSK2110183B; GSK 2110183B; GSK2110183B; Afuresertib. Grade: >98%. CAS No. 1047645-82-8. Molecular formula: C18H18Cl3FN4OS. Mole weight: 463.78. | |
| Afuzosin EP Impurity A | Afuzosin EP Impurity A. Uses: For analytical and research use. Alternative Names: N-[3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)methylamino]propyl]furan-2-carboxamide. Molecular formula: C19H23N5O4. Mole weight: 385.42. Catalog: APB03232. |  |
| Afuzosin EP Impurity D | Afuzosin EP Impurity D. Uses: For analytical and research use. Alternative Names: N2-(3-aminopropyl)-6,7-dimethoxy-N2-methylquinazolin-2,4-diamine. Molecular formula: C14H21N5O2. Mole weight: 291.35. Catalog: APB03229. | |
| Afuzosin EP Impurity E | Afuzosin EP Impurity E. Uses: For analytical and research use. Alternative Names: N-[3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)methylamino]propyl]formamide. Molecular formula: C15H21N5O3. Mole weight: 319.36. Catalog: APB03228. | |
| Afuzosin EP Impurity F | Afuzosin EP Impurity F. Uses: For analytical and research use. Alternative Names: 6,7-dimethoxy-N2,N2-dimethylquinazoline-2,4-diamine. Molecular formula: C12H16N4O2. Mole weight: 248.28. Catalog: APB03227. | |
| Afuzosin EP Impurity G | Afuzosin EP Impurity G. Uses: For analytical and research use. Alternative Names: N2-[3-[(4-amino-6,7-dimethoxyquinazolin-2-yl)amino]propyl]-6,7-dimethoxy-N2-methylquinazoline-2,4-diamine. Molecular formula: C24H30N8O4. Mole weight: 494.55. Catalog: APB03226. | |
| Afuzosin hydrochloride | Afuzosin hydrochloride. Uses: For analytical and research use. Alternative Names: (2RS)-N-[3-[(4-Amino-6,7-dimethoxyquinazolin-2-yl)methylamino]propyl]oxolan-2-carboxamide hydrochloride. Molecular formula: C19H27N5O4. Mole weight: 389.45. Catalog: APB03234. | |
| Afzelechin | Afzelechin is isolated from the herbs of Celastrus orbiculatus. Uses: Anti-inflammatory activity. Synonyms: (2R)-2α-(4-Hydroxyphenyl)chroman-3β,5,7-triol; [2R,3S,(+)]-3,4-Dihydro-2-(4-hydroxyphenyl)-2H-1-benzopyran-3,5,7-triol. Grade: 98%. CAS No. 2545-00-8. Molecular formula: C15H14O5. Mole weight: 274.3. | |
| Afzelechin 3-O-xyloside | Afzelechin 3-O-xyloside is purified from the barks of Cassipourea gerrardii. Synonyms: (2S,3R,4S,5R)-2-[[(2R,3S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl]oxy]oxane-3,4,5-triol. Grade: 98.0%. CAS No. 512781-45-2. Molecular formula: C20H22O9. Mole weight: 406.38. | |
| Afzelechin-(4α?8)-epiafzelechin | Afzelechin-(4α→8)-epiafzelechin is a natural compound isolated from the herbs of Cassia javanica. Synonyms: (2R,3R)-2-(4-hydroxyphenyl)-8-[(2R,3S,4S)-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol. Grade: 97.5%. CAS No. 1383627-30-2. Molecular formula: C30H26O10. Mole weight: 546.52. | |
| Afzelin | Afzelin (Kaempferol-3-O-rhamnoside)It is a flavonol glycoside that has anti-inflammatory, anti-oxidative stress response, anti-apoptotic, and anti-cardiac cytotoxic effects. AfzelinIt can reduce mitochondrial damage, enhance mitochondrial biosynthesis, and reduce mitochondria-related proteins. Parkinand PTENinduced putative kinase 1 (putative kinase 1)s level. AfzelinCan be improved D-galactosamine(GalN)/LPSSurvival rate of mice treated with doxorubicin prophylaxis (HY-15142A)Induced cardiotoxicity and scopolamine (HY-N0296)-induced neurological injury. AfzelinAlso inhibits asthma and allergies caused by ovalbumin[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Kaempferol-3-O-rhamnoside. CAS No. 482-39-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1441. | |
| Afzelin | Afzelin. Group: Biochemicals. CAS No. 482-39-3. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Ag | Ag. Purity: 99.9%. |  |
| AG-012917 | AG-012917 is a broad spectrum cyclin-dependent kinase inhibitor with potential anticancer activity. Synonyms: AG 012917; AG012917; (S)-4-((4-amino-5-(2,6-difluorobenzoyl)thiazol-2-yl)amino)-N-((1-methylpyrrolidin-2-yl)methyl)benzamide. Grade: >98%. CAS No. 486414-16-8. Molecular formula: C23H23F2N5O2S. Mole weight: 471.52. | |
| AG-012986 | AG-012986 is a multitargeted cyclin-dependent kinase (CDK) inhibitor active against CDK1, CDK2, CDK4/6, CDK5, and CDK9, with selectivity over a diverse panel of non-CDK kinases. AG-012986 showed antiproliferative activities in vitro with IC(50)s of <100 nmol/L in 14 of 18 tumor cell lines. In vivo, significant antitumor efficacy induced by AG-012986 was seen (tumor growth inhibition,>83.1%) in 10 of 11 human xenograft tumor models. AG-012986 also showed dose-dependent retinoblastoma Ser(795) hypophosphorylation, cell cycle arrest, decreased Ki-67 tumor staining, and apoptosis in conjunction with antitumor activity. Synonyms: AG 012986; AG012986; Benzamide, 4-((4-amino-5-(2,6-difluorobenzoyl)-2-thiazolyl)amino)-N-((1R)-2-(dimethylamino)-1-methylethyl)-. Grade: >98%. CAS No. 486414-35-1. Molecular formula: C22H23F2N5O2S. Mole weight: 459.51. | |
| AG-012986 | AG-012986 is a pan-CDK inhibitor with Ki values of 44 nM (CDK1), 9.2 nM (CDK4), 94 nM (CDK2), and IC50 values of 22 nM (CDK5), 4 nM (CDK9). AG-012986 causes apoptosis of T-cells by targeting upstream kinases in the p38 Mitogen-activated protein kinase (MAPK) pathway and impairing cellular survival. AG-012986 induces cell cycle arrest, retinoblastoma protein hypophosphorylation, and reduces Ki-67 expression. AG-012986 exerts antiproliferative activity in tumor cells, demonstrates antitumor efficacy in human xenograft models, and causes retinal and peripheral neurotoxicity, plus immune cell toxicity. AG-012986 can be used for the research of colon carcinoma, non-small cell lung carcinoma, lung carcinoma, breast carcinoma, ovarian tumor, pancreatic carcinoma, osteosarcoma, lymphoma, leukemia, retinotoxicity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 486414-35-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119715. | |
| AG013736 (AxitinibAxitinib) | Axitinib (also known as AG013736) is a small molecule tyrosine kinase inhibitor under development by Pfizer. It inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, platelet derived growth factor receptor (PDGFR), and cKIT (CD117). It has been shown to significantly inhibit growth of breast cancer in xenograft models [1] and has been successful in trials with renal cell carcinoma (RCC) [2] and several other tumor types [3]. Group: Biochemicals. Alternative Names: N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide; AG 013736. Grades: Purified. CAS No. 319460-85-0. Pack Sizes: 50mg, 100mg. US Biological Life Sciences. | Worldwide |
| AG-024104 | AG-024104 is a broad spectrum cyclin-dependent kinase inhibitor with potential anticancer activity. Synonyms: AG 024104; AG024104. Grade: >98%. CAS No. 750575-23-6. Molecular formula: C24H28F2N6O4S2. Mole weight: 566.64. | |
| AG-024322 | AG-24322 is a second generation CDK inhibitor. AG-024322 is a potent inhibitor of CDK1, CDK2, and CDK4 that produces cell-cycle arrest and antitumor activity in preclinical models. Synonyms: AG-24322; AG 24322; AG24322. Grade: 98%. CAS No. 837364-57-5. Molecular formula: C23H20F2N6. Mole weight: 418.44. | |
| AG-024322 | AG-024322 is a potent ATP-competitive pan-CDK inhibitor against cell cycle kinases CDK1, CDK2, and CDK4 with Ki values in the 1-3 nM range[1]. AG-024322 displays broad-spectrum anti-tumor activity and clear target modulation in vivo. AG-024322 induces cell apoptosis[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 837364-57-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15491. | |
| AG-041R | AG-041R is a potent gastrin/CCK2 receptor antagonist that exhibits selective binding for CCK2 compared to CCK1. Synonyms: 1H-Indole-3-acetamide, 1-(2,2-diethoxyethyl)-2,3-dihydro-N-(4-methylphenyl)-3-[[[(4-methylphenyl)amino]carbonyl]amino]-2-oxo-, (+)-; (+)-1-(2,2-Diethoxyethyl)-2,3-dihydro-N-(4-methylphenyl)-3-[[[(4-methylphenyl)amino]carbonyl]amino]-2-oxo-1H-indole-3-acetamide; (+)-AG 041R; AG 041R; (R)-2-(1-(2,2-diethoxyethyl)-2-oxo-3-(3-(p-tolyl)ureido)indolin-3-yl)-N-(p-tolyl)acetamide. Grade: ≥98%. CAS No. 159883-95-1. Molecular formula: C31H36N4O5. Mole weight: 544.64. | |
| AG 045572 | AG 045572, a nonpeptidic GnRH antagonist, could probably be used in the treatment for sex hormone-dependent diseases and infertility. Synonyms: AG 045572; AG045572; AG-045572; 5-[5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl-methyl]-N-(2,4,6-trimethoxyphenyl)-2-furancarboxamide. Grade: ≥97% by HPLC. CAS No. 263847-55-8. Molecular formula: C30H37NO5. Mole weight: 491.62. | |
| AG 045572 | AG 045572. Group: Biochemicals. Grades: Purified. CAS No. 263847-55-8. Pack Sizes: 1mg, 10mg. US Biological Life Sciences. | Worldwide |
| AG-09/1 | AG-09/1. Synonyms: 2-[(6-methoxy-1H-benzimidazol-2-yl)thio]-N-(4-nitrophenyl)-acetamide. CAS No. 356776-32-4. Molecular formula: C16H14N4O4S. Mole weight: 358.37. | |
| AG1024 | AG1024 (Tyrphostin AG 1024) is a reversible, competitive and selective IGF-1R inhibitor with an IC50 of 7 μM. AG1024 inhibits phosphorylation of IR (IC50=57 μM). AG1024 induces apoptosis and has anti-cancer activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tyrphostin AG 1024. CAS No. 65678-07-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10253. | |
| AG-1024 | AG-1024 is also called Tyrphostin, is a selective inhibitor of IGF-1R. AG-1024 was used to evaluate effects on proliferation, radiosensitivity, and radiation-induced cell apoptosis in a human breast cancer cell line MCF-7. Exposure to Tyrphostin AG 1024 inhibited proliferation and induced apoptosis in a time-dependent manner, and the degree of growth inhibition for IC20 plus irradiation (4 Gy) was up to 50% compared to the control. Synonyms: AG1024; AG-1024; AG 1024. Tyrphostin. Grade: >98%. CAS No. 65678-07-1. Molecular formula: C21H27N7O. Mole weight: 393.23. | |
| AG-120 (Ivosidenib) | Ivosidenib (AG-120) is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity. Group: Inhibitors. CAS No. 1448347-49-6. Pack Sizes: 5mg. Product ID: S8206. Formula: C28H22ClF3N6O3. Smiles: C1CC(=O)N(C1C(=O)N(C2=CC(=CN=C2)F)C(C3=CC=CC=C3Cl)C(=O)NC4CC(C4)(F)F)C5=NC=CC(=C5)C#N. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| AG 126 | Tyrphostins are protein tyrosine kinase inhibitors developed to inhibit cell growth through blocking the activity of certain GFRK (growth factor receptor kinases). AG 126 selectively inhibits the phosphorylation of ERK1 and ERK2 at 25-50 μM. It also inhibits the production of TNF-α (tumor necrosis factor-α), attenuating signaling through NF-κB, the induced expression of COX-2 and iNOS, and the inflammatory response in animal models. AG 126 is a poor inhibitor of epidermal GFRK with IC50 of 450 μM and platelet-derived GFRK with IC50 > 100 μM. AG 126 may represent a new approach for the therapy of inflammation. Uses: Anti- inflammation. Synonyms: AG126; AG-126; Tyrphostin AG 126; UNII-7YA4AMD1JC; Tyrphostin A 10; alpha-Cyano-(3-hydroxy-4-nitro)cinnamonitrile. Grade: 95%. CAS No. 118409-62-4. Molecular formula: C10H5N3O3. Mole weight: 215.16. | |
| AG1295 | Tyrphostin AG 1295 is a selective inhibitor of PDGFR (platelet-derived growth factor receptor) protein tyrosine kinase (PDGF-receptor PTK)(IC50 = 500 nM) and PDGF-dependent DNA synthesis (IC50 = 2.5 μM) in Swiss/3T3 cells. Synonyms: AG1295; AG 1295; AG 1295; NSC 380341; NSC380341; NSC-380341; Tyrphostin AG 1295. Grade: >98%. CAS No. 71897-07-9. Molecular formula: C16H14N2. Mole weight: 234.30. | |
| AG-1295 | AG-1295. Group: Biochemicals. Alternative Names: 6,7-Dimethyl-2-phenyl-quinoxaline; 2-Phenyl-6,7-dimethylquinoxaline; 6,7-Dimethyl-2-phenylquinoxaline; AG 1295; NSC 380341; Tyrphostin AG 1295. Grades: Highly Purified. CAS No. 71897-07-9. Pack Sizes: 10mg. Molecular Formula: C16H14N2, Molecular Weight: 234.3. US Biological Life Sciences. | Worldwide |
| AG 13958 | AG 13958 is a VEGFR tyrosine kinase inhibitor used for treatment of age-related macular degeneration (AMD). Synonyms: AG-13958; AG13958. CAS No. 319460-94-1. Molecular formula: C26H22FN7O. Mole weight: 467.50. | |
| AG-13958 | AG-13958 (AG-013958), a potent VEGFR tyrosine kinase inhibitor, is used for treatment of choroidal neovascularization associated with age-related macular degeneration (AMD)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AG-013958. CAS No. 319460-94-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15492. | |
| AG 1406 | AG 1406 is an inhibitor of tyrosine phosphorylation. Synonyms: 2-[[4-hydroxy-3,5-di(propan-2-yl)phenyl]methylidene]propanedinitrile; Propanedinitrile, [[4-hydroxy-3,5-bis(1-methylethyl)phenyl]methylene]-; CTK2G2659; AG1406; CTK2G 2659; AG 1406; CTK2G-2659; AG-1406. CAS No. 71308-34-4. Molecular formula: C16H18N2O. Mole weight: 254.333. | |
| AG14361 | AG14361 is a potent PARP-1 inhibitor, with a Ki of < 5 nM, and in permeabilized SW620 and intact SW620 cells, the IC50s are 29 nM and 14 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 328543-09-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12032. | |
| AG-14361 | AG14361 is a PARP-1 inhibitor with Ki < 5 nmol/L. AG14361 is at least 1000-fold more potent than the benzamides. The IC50 for AG14361 is 29 nM in permeabilized SW620 cells and 14 nM in intact SW620 cells. Synonyms: AG14361; AG-14361; AG 14361. Grade:>98%. CAS No. 328543-09-5. Molecular formula: C19H20N4O. Mole weight: 320.39. | |
| AG-1478 | AG-1478 (NSC 693255) is a selective EGFR inhibitor with IC50 of 3 nM; almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR. Uses: Enzyme inhibitors. Synonyms: Tyrphostin AG-1478; AG-1478; AG1478; AG 1478. Grade: >98%. CAS No. 153436-53-4. Molecular formula: C16H14ClN3O2. Mole weight: 315.75. | |
| AG-1478 | AG-1478 is a selective EGFR inhibitor with IC50 of 3 nM in cell-free assays, almost no activity on HER2-Neu, PDGFR, Trk, Bcr-Abl and InsR. AG-1478 (Tyrphostin AG-1478) inhibits encephalomyocarditis virus (EMCV) and hepatitis c virus (HCV) by targeting phosphatidylinositol 4-kinase IIIα (PI4KA). Group: Inhibitors. Alternative Names: Tyrphostin AG-1478, NSC 693255. CAS No. 153436-53-4,175178-82-2. Pack Sizes: 5mg. Product ID: S2728. Formula: C16H14ClN3O2. Smiles: COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Cl)OC. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| AG-1478 | AG-1478 (Tyrphostin AG-1478) is a selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM. AG-1478 has antiviral effects against HCV and encephalomyocarditis virus (EMCV). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tyrphostin AG-1478; NSC 693255. CAS No. 153436-53-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13524. | |
| AG 1478 hydrochloride | The hydrochloride salt form of AG 1478, which has been found to be an epidermal growth factor receptor tyrosine kinase inhibitor. Synonyms: AG 1478 hydrochloride; AG1478 hydrochloride; AG-1478 hydrochloride; N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinanine hydrochloride. Grade: ≥98% by HPLC. CAS No. 170449-18-0. Molecular formula: C16H14ClN3O2.HCl. Mole weight: 352.22. | |
| AG-1557 | AG-1557 is an inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. Synonyms: AG-1557; AG 1557; AG1557; N-(3-Iodophenyl)-6,7-dimethoxyquinazolin-4-amine. CAS No. 189290-58-2. Molecular formula: C16H14IN3O2. Mole weight: 407.211. | |
| AG-1557 hydrochloride | AG-1557 hydrochloride is a specific and ATP competitive inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. Synonyms: AG 1557 hydrochloride; AG1557 hydrochloride. Molecular formula: C16H15ClIN3O2. Mole weight: 443.66. | |
| AG 18 | AG 18. Group: Biochemicals. Grades: Purified. CAS No. 118409-57-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AG-18 | AG 18 (10 μM) inhibits EGF-induced proliferation of GH3 cells. Synonyms: RG-50810; RG 50810; RG50810; Tyrphostin A23; AG-18; AG 18; AG18; TX 825; Tyrphostin A23; Tyrphostin AG-18. Grade: >98%. CAS No. 118409-57-7. Molecular formula: C10H6N2O2. Mole weight: 186.17. | |
| AG-1801 | AG-1801is a bio-active chemical for treatment of cell proliferative diseases. Synonyms: (E)-N-benzyl-2-cyano-3-(4-nitrophenyl)prop-2-enamide; UNII-WYN000A4MH; STK361572; AG-1801; AG1801; AG 1801. Grade: >98%. CAS No. 204010-55-9. Molecular formula: C17H13N3O3. Mole weight: 307.3. | |
| AG 1812 | This active molecular is a bio-active chemical and detailed information has not been published yet. Synonyms: AG 1812; AG1812; AG-1812; 2-[2-[[[1-(1H-benzimidazol-2-yl)-3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-1-ium-2-yl]methyldisulfanyl]methyl]-3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-1-ium-1-yl]-1H-benzimidazole; dichloride. Grade: 98%. CAS No. 114559-57-8. Molecular formula: C32H28Cl2F6N6O2S2. Mole weight: 777.63. | |
| AG-1812 Free base | AG-1812 is a Lansoprazole disulfide active metabolite. Synonyms: AG-1812; AG 1812; AG1812; 2,2'-(dithiobis(methylene))bis(1-(1H-benzimidazol-2-yl)-3-methyl-4-(2,2,2-trifluoroethoxy)-Pyridinium; Lansoprazole disulfide active metabolite; UNII-6RI44GB0V9; AC1MIZB6; HE078804. Grade: 98%. CAS No. 700341-80-6. Molecular formula: C32H28F6N6O2S22+. Mole weight: 706.73. | |
| AG-183 | AG-183 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 0.8 μM in the human epidermoid carcinoma cell line A431. Synonyms: Tyrphostin 51; Tyrphostin AG 183. Grade: ≥98%. CAS No. 122520-90-5. Molecular formula: C13H8N4O3. Mole weight: 268.2. | |
| AG 1-X2 ion exchange resin 200-400 acetate | AG 1-X2 ion exchange resin 200-400 acetate. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| AG2000 Free Base | AG2000 Free Base is a bio-active chemical compound. It is also a lansoprazole sulfenamide active metabolite. Synonyms: AG-2000 Free Base; AG2000 Free Base; 4-Methyl-3-(2,2,2-trifluoroethoxy)-5H-pyrido[1',2':4,5][1,2,4]thiadiazino[2,3-a]benzimidazol-13-ium; AG-2000 free base; Lansoprazole sulfenamide active metabolite. Grade: >98%. CAS No. 111712-15-3. Molecular formula: C16H13F3N3OS+. Mole weight: 352.35. | |
| AG 205 | AG 205 is a progesterone receptor membrane component 1 (Pgrmc1) ligand. It inhibits cell cycle progression and cell viability in cancer cell lines. It inhibits progesterone induced cytosolic Ca2+ increases in GnRH neurons in vitro. Synonyms: Cis-2-[[1-(4-Chlorophenyl)-1H-tetrazol-5-yl]thio]-1-(1,2,3,4,4a,9b-hexahydro-2,8-dimethyl-5H-pyrido[4,3-b]indol-5-yl)-ethanone. Grade: ≥98%. CAS No. 442656-02-2. Molecular formula: C22H23ClN6OS. Mole weight: 454.98. | |
| AG-213 | AG-213 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 2.4 μM in the human epidermoid carcinoma cell line A431. Uses: Enzyme inhibitors. Synonyms: Tyrphostin AG-213; Tyrphostin 47; (E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enethioamide. Grade: ≥97%. CAS No. 122520-86-9. Molecular formula: C10H8N2O2S. Mole weight: 220.2. | |
| AG-270 | AG-270 is an allosteric, noncompetitive, first-in-class, reversible and orally active MAT2A inhibitor, with an IC50 of 14 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2201056-66-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-138630. | |
| AG28262 | AG28262 is a bio-active chemical compound. It is a VEFG-r2 inhibitor and could cause an increase in serum ALT, due in part to both gene up-regulation. Synonyms: AG-28262; AG 28262; AG28262; Benzo(b)thiophene-3-carboxamide, N,2-dimethyl-6-((2-(1-methyl-1H-imidazol-2-yl)thieno(3,2-b)pyridin-7-yl)oxy)-; N,2-dimethyl-6-[2-(1-methylimidazol-2-yl)thieno[3,2-b]pyridin-7-yl]oxy-1-benzothiophene-3-carboxamide. Grade: 98%. CAS No. 638216-89-4. Molecular formula: C22H18N4O2S2. Mole weight: 434.53. | |
| AG-348 sulfate hydrate | AG-348 sulfate hydrate is an orally active pyruvate kinase allosteric activator. Synonyms: Mitapivat hemisulfate sesquihydrate; AG-348 hemisulfate sesquihydrate; Pyrukynd; 8-Quinolinesulfonamide, N-(4-((4-(cyclopropylmethyl)-1-piperazinyl)carbonyl)phenyl)-, sulfate, hydrate (2:1:3). CAS No. 2151847-10-6. Molecular formula: C48H60N8O13S3. Mole weight: 1053.23. | |
| AG-370 | AG-370 is a selective inhibitor of PDGF receptor kinase with an IC50 value of 20 μM in human bone marrow fibroblasts. It displays comparatively weak inhibition of the EGF receptor (IC50 = 820 μM). Synonyms: NSC 651712; 2-pentenetricarbonitrile, 3-amino-4-(1h-indol-5-ylmethylene)-. Grade: ≥95%. CAS No. 134036-53-6. Molecular formula: C15H9N5. Mole weight: 259.3. | |
| AG490 | AG490 (Tyrphostin AG490) is a tyrosine kinase inhibitor that inhibits EGFR, Stat-3 and JAK2/3. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Tyrphostin AG490; Tyrphostin B42. CAS No. 133550-30-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12000. | |
| AG 490 | AG 490. Group: Biochemicals. Grades: Purified. CAS No. 133550-30-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AG-490 | Tyrphostin AG490 is a JAK-2 specific inhibitor, which inhibits phosphorylation of EGFR and signal transducer and activator of transcription 3 [STAT-3], and subsequently reduce invasion and adhesion potential of malignant cells. Uses: Antineoplastic agents. Synonyms: Tyrphostin AG 490; AG-490; AG490. Grade: 0.98. CAS No. 133550-30-8. Molecular formula: C17H14N2O3. Mole weight: 294.31. | |
| AG-490 | AG-490. Group: Biochemicals. Alternative Names: 2-Cyano-3-(3,4-dihydroxyphenyl)-N-(phenylmethyl)-2-propenamide; Tyrphostin B 42. Grades: Highly Purified. CAS No. 134036-52-5. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C17H14N2O3. US Biological Life Sciences. | Worldwide |
| AG 490 (Tyrphostin B42, N-benzyl-3, 4-dihydroxy-benzylidene cyanoacetamide) | Specific and potent JAK2 protein tyrosine kinase inhibitor. Also, inhibits EGF receptor autophosphorylation, with IC50 of 100nM. Inhibits DNA synthesis and cell growth; induces apoptosis. Blocks growth of leukemic cells in vitro and in vivo. Group: Biochemicals. Alternative Names: Tyrphostin B42. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| AG 494 | AG 494. Group: Biochemicals. Grades: Purified. CAS No. 133550-35-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AG 494 | AG-494 is a EGFR (epidermal growth factor receptor) kinase inhibitor with IC50 value of 0.7 μM. It is selective over ErbB2, PDGFR and insulin receptor kinase (IC50 values are 42, 6 and > 100 μM respectively). AG-494 tyrphostin also can block Cdk2 activation. Synonyms: alpha-Cyano-(3,4-dihydroxy)-N-phenylcinnamide; Tyrphostin AG-494; Tyrphostin B48. Grade: 98%. CAS No. 139087-53-9. Molecular formula: C16H12N2O3. Mole weight: 280.28. | |
| AG-5507 | AG-5507 is a bio-active chemical howerver, its detailed information has not been published. Uses: A bio-active chemical. Synonyms: AG-5507; AG5507; AG 5507; UNII-I518B5DK9I; (7R,11S)-2-(3,5-dimethoxyphenyl)-12-(2-(3,5-dimethoxyphenyl)-2-oxoacetyl)-8,9,10,11-tetrahydro-2H-7,11-epiminopyrazino[1,2-a]azocine-3,6(4H,7H)-dione. Grade: ≥95%. CAS No. 294865-05-7. Molecular formula: C28H29N3O8. Mole weight: 535.19. | |
| AG 555 | AG 555 is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (IC50 = 0.7 μM) with 50-fold and >140-fold selectivity over ErbB2 and insulin receptor kinase respectively. Synonyms: AG 555; AG-555; AG555; (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide; AG 555; AG-555; alpha-cyano-(3,4-dihydroxy)-N-(3-phenylpropyl)cinnamide; N-(3'-Phenylpropyl)-3,4-dihydroxybenzylidenecyanoacetamide; N-(3-phenylpropyl)-3,4-dihydroxybenzylidene cyanoacetamide; tyrphostin AG 555; tyrphostin AG-555; tyrphostin B46. Grade: ≥98% (HPLC). CAS No. 133550-34-2. Molecular formula: C19H18N2O3. Mole weight: 322.36. | |
| AG 555 | AG 555. Group: Biochemicals. Grades: Purified. CAS No. 133550-34-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AG 556 | AG 556. Group: Biochemicals. Grades: Purified. CAS No. 133550-41-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
Our database is helping our users find suppliers everyday.
