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| Product | Description | |
|---|---|---|
| Afatinib D6 | Afatinib D6 (BIBW 2992 D6) is a deuterium-labeled Afatinib. Afatinib is an irreversible EGFR family inhibitor. Category: Active pharmaceutical ingredients. CAS No. 1313874-96-2. Product ID: API1313874962. Molecular formula: C24H25ClFN5O3. Mole weight: 491.98. |  |
| Afatinib-[d6] Dimaleate | One of the isotopic labelled form of Afatinib Dimaleate, which could be used in the treatment of some cancer and diseases of espiratory tract. Synonyms: (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quizolinyl]-4-dimethylamino)-2-butemide Dimaleate. Grade: 95% by HPLC; 98% atom D. Molecular formula: C32H27D6ClFN5O11. Mole weight: 724.13. |  |
| Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl (Contained ~8.5% Ethanol) | Afatinib-des(4-dimethylamino-2-en-1-oxo)butyl is a reactant in the synthesis of Afatinib (A355300), an aminocrotonylamino-substituted quinazoline derivative used for treating cancer and diseases of the respiratory tract, lungs, gastrointestinal tract, bile duct, and gallbladder. Group: Biochemicals. Grades: Highly Purified. CAS No. 314771-76-1. Pack Sizes: 100mg, 1g. Molecular Formula: C18H16ClFN4O2. US Biological Life Sciences. |  Worldwide |
| Afatinib dimaleate | Afatinib Dimaleate irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively. Synonyms: (2E)-N-[4-[(3,4-difluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide. Grade: >98%. CAS No. 850140-73-7. Molecular formula: C32H33ClFN5O11. Mole weight: 717.18. | |
| Afatinib dimaleate | Afatinib (BIBW 2992) dimaleate is an orally active, potent and irreversible dual specificity inhibitor of ErbB family (EGFR and HER2), with IC50 values of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively. Afatinib dimaleate can be used for the research of esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BIBW 2992MA2. CAS No. 850140-73-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-10261A. |  |
| Afatinib impurity 10 | Afatinib impurity 10. Uses: For analytical and research use. CAS No. 2223677-63-0. Molecular formula: C24H25Cl2N5O3. Mole weight: 502.4. Catalog: APB2223677630. |  |
| Afatinib impurity 11 | Afatinib impurity 11. Uses: For analytical and research use. CAS No. 2223677-62-9. Molecular formula: C24H25F2N5O3. Mole weight: 469.49. Catalog: APB2223677629. | |
| Afatinib impurity 11 | Afatinib impurity 11 is an impurity of Afatinib, which is an irreversible EGFR family inhibitor used to treat non-small cell lung cancer (NSCLC). Synonyms: 2-Propenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-; (S)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)acrylamide; N-{4-[(3-Chloro-4-fluorophenyl)amino]-7-[(3S)-tetrahydro-3-furanyloxy]-6-quinazolinyl}acrylamide. Grade: ≥95%. CAS No. 1402086-20-7. Molecular formula: C21H18ClFN4O3. Mole weight: 428.84. | |
| Afatinib impurity 12 | Afatinib impurity 12. Uses: For analytical and research use. Molecular formula: C24H25ClFN5O3. Mole weight: 485.94. Catalog: APB10916. | |
| Afatinib impurity 13 | Afatinib impurity 13. Uses: For analytical and research use. CAS No. 2223677-64-1. Molecular formula: C22H20ClFN4O3. Mole weight: 442.88. Catalog: APB2223677641. | |
| Afatinib impurity 14 | Afatinib impurity 14. Uses: For analytical and research use. CAS No. 1637254-93-3. Molecular formula: C22H19BrClFN4O3. Mole weight: 521.77. Catalog: APB1637254933. | |
| Afatinib impurity 14 | Afatinib impurity 14. Uses: For analytical and research use. Alternative Names: (E)-4-isopropoxybut-2-enoic acid. Molecular formula: C7H12O3. Mole weight: 144.17. Catalog: APB02310. | |
| Afatinib impurity 15 | Afatinib impurity 15. Uses: For analytical and research use. Alternative Names: N1,N6-bis(3-chloro-4-fluorophenyl)-7-nitroisoquinoline-1,6-diamine. Molecular formula: C21H12Cl2F2N4O2. Mole weight: 461.25. Catalog: APB02309. | |
| Afatinib impurity 15 | Afatinib impurity 15. Uses: For analytical and research use. CAS No. 2413212-13-0. Molecular formula: C23H23ClFN5O3. Mole weight: 471.92. Catalog: APB2413212130. | |
| Afatinib impurity 16 | Afatinib impurity 16. Uses: For analytical and research use. Alternative Names: 7-fluoro-4-isopropoxy-6-nitroquinazoline. Molecular formula: C11H10FN3O3. Mole weight: 251.21. Catalog: APB02308. | |
| Afatinib impurity 17 | Afatinib impurity 17. Uses: For analytical and research use. Alternative Names: 1000397-30-7(HCl); 4-chloro-7-fluoro-6-nitroquinazoline. CAS No. 162012-70-6. Molecular formula: C8H3ClFN3O2. Mole weight: 227.58. Catalog: APB162012706. | |
| Afatinib impurity 18 | Afatinib impurity 18. Uses: For analytical and research use. Alternative Names: (S)-7-fluoro-6-nitro-4-((tetrahydrofuran-3-yl)oxy)quinazoline. Molecular formula: C12H10FN3O4. Mole weight: 279.22. Catalog: APB02307. | |
| Afatinib impurity 19 | Afatinib impurity 19. Uses: For analytical and research use. Alternative Names: N-(3,4-dichlorophenyl)-7-fluoro-6-nitroquinazolin-4-amine. Molecular formula: C14H7Cl2FN4O2. Mole weight: 353.14. Catalog: APB02306. | |
| Afatinib impurity 2 | Afatinib impurity 2. Uses: For analytical and research use. CAS No. 2413212-11-8. Molecular formula: C24H25ClFN5O4. Mole weight: 501.94. Catalog: APB2413212118. | |
| Afatinib Impurity 2 | An analogue of Afatinib. Synonyms: 7-Quinazolinol, 4-[(3-chloro-4-fluorophenyl)?amino]?-6-nitro-. Grade: > 95%. CAS No. 1449430-45-8. Molecular formula: C14H8ClFN4O3. Mole weight: 334.7. | |
| Afatinib impurity 20 | Afatinib impurity 20. Uses: For analytical and research use. Alternative Names: 6-nitro-4,7-bis(((S)-tetrahydrofuran-3-yl)oxy)quinazoline. Molecular formula: C16H17N3O6. Mole weight: 347.32. Catalog: APB02304. | |
| Afatinib impurity 20 | Afatinib impurity 20. Uses: For analytical and research use. CAS No. 1027929-81-2. Molecular formula: C8H4FN3O3. Mole weight: 209.14. Catalog: APB1027929812. | |
| Afatinib impurity 21 | Afatinib impurity 21. Uses: For analytical and research use. Alternative Names: N-(3-chloro-4-(((S)-tetrahydrofuran-3-yl)oxy)phenyl)-6-nitro-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-4-amine. Molecular formula: C22H21ClN4O6. Mole weight: 472.88. Catalog: APB02305. | |
| Afatinib impurity 22 | Afatinib impurity 22. Uses: For analytical and research use. Alternative Names: (S)-4-isopropoxy-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazoline. Molecular formula: C15H17N3O5. Mole weight: 319.31. Catalog: APB02302. | |
| Afatinib impurity 23 | Afatinib impurity 23. Uses: For analytical and research use. Alternative Names: (S,E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-isopropoxybut-2-enamide. Molecular formula: C25H26ClFN4O4. Mole weight: 500.95. Catalog: APB02301. | |
| Afatinib impurity 24 | Afatinib impurity 24. Uses: For analytical and research use. Alternative Names: (S,E)-4-(dimethylamino)-N-(4-((4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)but-2-enamide. Molecular formula: C24H26FN5O3. Mole weight: 451.49. Catalog: APB02303. | |
| Afatinib impurity 25 | Afatinib impurity 25. Uses: For analytical and research use. Alternative Names: 4-((3-chloro-4-fluorophenyl)amino)-6-(2-hydroxy-5-oxopyrrolidin-1-yl)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazoline 1-oxide. Molecular formula: C22H20ClFN4O5. Mole weight: 474.87. Catalog: APB02299. | |
| Afatinib impurity 26 | Afatinib impurity 26. Uses: For analytical and research use. Alternative Names: N-(4-((3-chloro-4-fluorophenyl)amino)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-3,4-bis(dimethylamino)butanamide. Molecular formula: C26H32ClFN6O3. Mole weight: 531.02. Catalog: APB02300. | |
| Afatinib impurity 27 | Afatinib impurity 27. Uses: For analytical and research use. Alternative Names: N1,N6-bis(3-chloro-4-fluorophenyl)isoquinoline-1,6,7-triamine. Molecular formula: C21H14Cl2F2N4. Mole weight: 431.27. Catalog: APB02297. | |
| Afatinib impurity 28 | Afatinib impurity 28. Uses: For analytical and research use. Alternative Names: 7-fluoro-4-isopropoxyquinazolin-6-amine. Molecular formula: C11H12FN3O. Mole weight: 221.23. Catalog: APB02298. | |
| Afatinib impurity 29 | Afatinib impurity 29. Uses: For analytical and research use. Alternative Names: 4-chloro-7-fluoroquinazolin-6-amine. Molecular formula: C8H5ClFN3. Mole weight: 197.6. Catalog: APB02296. | |
| Afatinib Impurity 2F3Cl-1 | An impurity of Afatinib, a medication used to treat non-small cell lung carcinoma (NSCLC). Synonyms: 4-Quinazolinamine, N-(3-chloro-2-fluorophenyl)-7-fluoro-6-nitro-. Grade: ≥95%. CAS No. 936558-43-9. Molecular formula: C14H7ClF2N4O2. Mole weight: 336.68. | |
| Afatinib impurity 30 | Afatinib impurity 30. Uses: For analytical and research use. Alternative Names: (S)-7-fluoro-4-((tetrahydrofuran-3-yl)oxy)quinazolin-6-amine. Molecular formula: C12H12FN3O2. Mole weight: 249.24. Catalog: APB02295. | |
| Afatinib impurity 31 | Afatinib impurity 31. Uses: For analytical and research use. Alternative Names: N4-(4-chloro-3-fluorophenyl)-7-fluoroquinazoline-4,6-diamine. Molecular formula: C14H9ClF2N4. Mole weight: 306.7. Catalog: APB02293. | |
| Afatinib impurity 32 | Afatinib impurity 32. Uses: For analytical and research use. Alternative Names: N4-(3,4-dichlorophenyl)-7-fluoroquinazoline-4,6-diamine. Molecular formula: C14H9Cl2FN4. Mole weight: 323.15. Catalog: APB02294. | |
| Afatinib impurity 33 | Afatinib impurity 33. Uses: For analytical and research use. Alternative Names: 4,7-bis(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-6-amine. Molecular formula: C16H19N3O4. Mole weight: 317.34. Catalog: APB02292. | |
| Afatinib impurity 34 | Afatinib impurity 34. Uses: For analytical and research use. Alternative Names: N4-(3-chloro-4-(((S)-tetrahydrofuran-3-yl)oxy)phenyl)-7-(((S)-tetrahydrofuran-3-yl)oxy)quinazoline-4,6-diamine. Molecular formula: C22H23ClN4O4. Mole weight: 442.9. Catalog: APB02291. | |
| Afatinib impurity 35 | Afatinib impurity 35. Uses: For analytical and research use. Alternative Names: (S)-4-isopropoxy-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-amine. Molecular formula: C15H19N3O3. Mole weight: 289.33. Catalog: APB02290. | |
| Afatinib impurity 36 | Afatinib impurity 36. Uses: For analytical and research use. Alternative Names: 2-amino-4-fluoro-5-nitrobenzoic acid. CAS No. 1194097-41-0. Molecular formula: C7H5FN2O4. Mole weight: 200.12. Catalog: APB1194097410. | |
| Afatinib impurity 37 | Afatinib impurity 37. Uses: For analytical and research use. Alternative Names: 7-fluoro-8-nitroquinazolin-4-ol. Molecular formula: C8H4FN3O3. Mole weight: 209.13. Catalog: APB02289. | |
| Afatinib impurity 38 | Afatinib impurity 38. Uses: For analytical and research use. Alternative Names: (S)-ethyl 4-chloro-3-hydroxybutanoate. CAS No. 86728-85-0. Molecular formula: C6H11ClO3. Mole weight: 166.6. Catalog: APB86728850. | |
| Afatinib impurity 39 | Afatinib impurity 39. Uses: For analytical and research use. Alternative Names: (S)-4-chlorobutane-1,3-diol. CAS No. 139013-68-6. Molecular formula: C4H9ClO2. Mole weight: 124.57. Catalog: APB139013686. | |
| Afatinib impurity 40 | Afatinib impurity 40. Uses: For analytical and research use. Alternative Names: (S)-4-((S)-4-chloro-3-hydroxybutoxy)butane-1,3-diol. Molecular formula: C8H17ClO4. Mole weight: 212.67. Catalog: APB02288. | |
| Afatinib impurity 41 | Afatinib impurity 41. Uses: For analytical and research use. Alternative Names: (E)-4-(methylamino)but-2-enoic acid compound with 2,2,2-trifluoroacetic acid (1:1). CAS No. 69169-63-7. Molecular formula: C7H10F3NO4. Mole weight: 229.15. Catalog: APB69169637. | |
| Afatinib impurity 42 | Afatinib impurity 42. Uses: For analytical and research use. Alternative Names: (E)-4-aminobut-2-enoic acid. CAS No. 38090-53-8. Molecular formula: C4H7NO2. Mole weight: 101.1. Catalog: APB38090538. | |
| Afatinib impurity 43 | Afatinib impurity 43. Uses: For analytical and research use. Alternative Names: (E)-4-(dimethylamino)-N,N-dimethylbut-2-enamide. Molecular formula: C8H16N2O. Mole weight: 156.23. Catalog: APB02287. | |
| Afatinib impurity 44 | Afatinib impurity 44. Uses: For analytical and research use. Alternative Names: (E)-methyl 4-(methylamino)but-2-enoate. CAS No. 915788-22-6. Molecular formula: C6H11NO2. Mole weight: 129.16. Catalog: APB915788226. | |
| Afatinib impurity 46 | Afatinib impurity 46. Uses: For analytical and research use. Alternative Names: (S)-N-(3,4-difluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine. Molecular formula: C18H14F2N4O4. Mole weight: 388.32. Catalog: APB02286. | |
| Afatinib impurity 47 | Afatinib impurity 47. Uses: For analytical and research use. Alternative Names: (S)-N-(3-chloro-2-fluorophenyl)-6-nitro-7-((tetrahydrofuran-3-yl)oxy)quinazolin-4-amine. Molecular formula: C18H14ClFN4O4. Mole weight: 404.78. Catalog: APB02284. | |
| Afatinib impurity 48 | Afatinib impurity 48. Uses: For analytical and research use. Alternative Names: (E)-N-(4-((3-chloro-4-fluorophenyl)(4-((4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)amino)-1-(dimethylamino)-4-oxobutan-2-yl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide. Molecular formula: C48H50Cl2F2N10O6. Mole weight: 971.88. Catalog: APB02285. | |
| Afatinib impurity 49 | Afatinib impurity 49. Uses: For analytical and research use. Alternative Names: (E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-hydroxybut-2-enamide. Molecular formula: C22H20ClFN4O4. Mole weight: 458.87. Catalog: APB02281. | |
| Afatinib impurity 5 | Afatinib impurity 5. Uses: For analytical and research use. Molecular formula: C28H33ClFN7O4. Mole weight: 586.07. Catalog: APB10915. | |
| Afatinib Impurity 5 | An analogue of Afatinib. Synonyms: 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)?-7-methoxy-6-nitro-. Grade: > 95%. CAS No. 179552-74-0. Molecular formula: C15H10ClFN4O3. Mole weight: 348.72. | |
| Afatinib impurity 50 | Afatinib impurity 50. Uses: For analytical and research use. Alternative Names: N-(3-chloro-2-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine. Molecular formula: C14H7ClF2N4O2. Mole weight: 336.68. Catalog: APB02283. | |
| Afatinib impurity 51 | Afatinib impurity 51. Uses: For analytical and research use. Alternative Names: N-(3,4-difluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine. Molecular formula: C14H7F3N4O2. Mole weight: 320.23. Catalog: APB02282. | |
| Afatinib impurity 52 | Afatinib impurity 52. Uses: For analytical and research use. Alternative Names: N-(3-chloro-4-fluorophenyl)-7-fluoroquinazolin-4-amine. Molecular formula: C14H8ClF2N3. Mole weight: 291.68. Catalog: APB02280. | |
| Afatinib Impurity 52 | Afatinib Impurity 52 is an impurity of Afatinib, a drug used to treat non-small cell lung cancer (NSCLC). Synonyms: (S)-diethyl 2-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-ylamino)-2-oxoethylphosphonate; Diethyl {[4-(3-Chloro-4-Fluoro-Phenylamino)-7-((S)-Tetrahydrofuran-3-Yloxy)-Quinazolin-6-Ylcarbamoyl]-Methyl}-Phosphonate. Grade: 95%. CAS No. 618061-76-0. Molecular formula: C24H27ClFN4O6P. Mole weight: 552.92. | |
| Afatinib impurity 53 | Afatinib impurity 53. Uses: For analytical and research use. Alternative Names: N-(3-chloro-4-fluorophenyl)-7-fluoro-8-nitroquinazolin-4-amine. CAS No. 2831861-00-6. Molecular formula: C14H7ClF2N4O2. Mole weight: 336.68. Catalog: APB2831861006. | |
| Afatinib impurity 54 | Afatinib impurity 54. Uses: For analytical and research use. Alternative Names: N-(3-chloro-4-fluorophenyl)-7-fluoro-6,8-dinitroquinazolin-4-amine. Molecular formula: C14H6ClF2N5O4. Mole weight: 381.68. Catalog: APB02279. | |
| Afatinib impurity 55 | Afatinib impurity 55. Uses: For analytical and research use. Alternative Names: 7-fluoro-6,8-dinitroquinazolin-4-ol. Molecular formula: C8H3FN4O5. Mole weight: 254.13. Catalog: APB02277. | |
| Afatinib impurity 56 | Afatinib impurity 56. Uses: For analytical and research use. Alternative Names: (Z)-4-(dimethylamino)but-2-enoic acid hydrochloride. Molecular formula: C6H12ClNO2. Mole weight: 165.62. Catalog: APB02278. | |
| Afatinib impurity 57 | Afatinib impurity 57. Uses: For analytical and research use. Alternative Names: (S,E)-4-(dimethylamino)-N-(4-oxo-7-((tetrahydrofuran-3-yl)oxy)-3,4-dihydroquinazolin-6-yl)but-2-enamide. CAS No. 1456696-14-2. Molecular formula: C18H22N4O4. Mole weight: 358.39. Catalog: APB1456696142. | |
| Afatinib impurity 6 | Afatinib impurity 6. Uses: For analytical and research use. CAS No. 350-46-9. Molecular formula: C6H4FNO2. Mole weight: 141.1. Catalog: APB350469. | |
| Afatinib impurity 65 | Afatinib impurity 65. Uses: For analytical and research use. Alternative Names: 2-amino-4-fluorobenzoic acid. CAS No. 446-32-2. Molecular formula: C7H6FNO2. Mole weight: 155.13. Catalog: APB446322. | |
| Afatinib impurity 66 | Afatinib impurity 66. Uses: For analytical and research use. Alternative Names: 2-chloro-1-fluoro-4-nitrobenzene. Molecular formula: C6H3ClFNO2. Mole weight: 175.54. Catalog: APB02271. | |
| Afatinib impurity 67 | Afatinib impurity 67. Uses: For analytical and research use. Alternative Names: 1,2-dichloro-4-nitrobenzene. Molecular formula: C6H3Cl2NO2. Mole weight: 192. Catalog: APB02270. | |
| Afatinib impurity 68 | Afatinib impurity 68. Uses: For analytical and research use. Alternative Names: 3-chloro-2-fluoroaniline. Molecular formula: C6H5ClFN. Mole weight: 145.56. Catalog: APB02269. | |
| Afatinib impurity 69 | Afatinib impurity 69. Uses: For analytical and research use. Alternative Names: (S)-4-chloro-3-hydroxybutanoic acid. CAS No. 106941-19-9. Molecular formula: C4H7ClO3. Mole weight: 138.55. Catalog: APB106941199. | |
| Afatinib impurity 7 | Afatinib impurity 7. Uses: For analytical and research use. CAS No. 1313874-96-2. Molecular formula: C24H19D6ClFN5O3. Mole weight: 491.98. Catalog: APB1313874962. | |
| Afatinib impurity 70 | Afatinib impurity 70. Uses: For analytical and research use. Alternative Names: (S)-4-chloro-3-hydroxybutanal. CAS No. 125781-04-6. Molecular formula: C4H7ClO2. Mole weight: 122.55. Catalog: APB125781046. | |
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