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| Product | Description | |
|---|---|---|
| Agigenin | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. |  |
| AgI Silica Core Shell Nanoparticles | AgI Silica Core Shell Nanoparticles. Group: Core shell nanoparticles. 99.9%. |  |
| AgI Silica Core Shell Nanoparticles | AgI Silica Core Shell Nanoparticles. Group: Core shell nanoparticles. CAS No. 67762-90-7. 99.9%. | |
| Agistatin B ((2R,4S,4aR,5R,6R,8aR)-6-Ethyloctahydro-2H-2,5-epoxy-chromene-4,4a-diol) | Tricyclic analog of agistatin A. Cholesterol biosynthesis inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 144096-46-8. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. |  Worldwide |
| Agistatin D ((4aS,5R,6R)-6-Ethyl-4a,5-dihydroxy-4a,5,6,7-tetrahydro-4H-chromen-4-one) | Analog of agistatin A. Cholesterol biosynthesis inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 144096-47-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Agistatin E | Agistatin E is a novel pyranacetal isolated from fungus FH-A 6239. It has been used as a cholesterol biosynthesis inhibitor. Mycotoxin. Synonyms: Agistatin E; 144096-48-0; (1S,3S,6R,7R,8R)-6-ethyl-3,8-dihydroxy-2,11-dioxatricyclo[5.3.1.03,8]undecan-9-one; HY-N10232; CS-0109121; J-007915. Grade: ≥98%. CAS No. 144096-48-0. Molecular formula: C11H16O5. Mole weight: 228.24. |  |
| Agistatin E ((2S,4aR,5S,8R,8aR)-8-Ethyl-4a,5-dihydroxy-hexahydro-2H-2,5-epoxychromen-4(3H)-one) | Tricyclic analog of agistatin A. Cholesterol biosynthesis inhibitor. Mycotoxin. Group: Biochemicals. Grades: Highly Purified. CAS No. 144096-48-0. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Agitoxin 2 | Agitoxin-2 is a potent and selective blocker of the Shaker type voltage-gated Kv1.3 and Kv1.1 channels. Agitoxin-2 inhibits Kv1.3 with an IC50 value of around 200 pM and Kv1.1 with an IC50 value of around 140 pM. Synonyms: AGTX2; H-Gly-Val-Pro-Ile-Asn-Val-Ser-Cys(1)-Thr-Gly-Ser-Pro-Gln-Cys(2)-Ile-Lys-Pro-Cys(3)-Lys-Asp-Ala-Gly-Met-Arg-Phe-Gly-Lys-Cys(1)-Met-Asn-Arg-Lys-Cys(2)-His-Cys(3)-Thr-Pro-Lys-OH; glycyl-L-valyl-L-prolyl-L-isoleucyl-L-asparagyl-L-valyl-L-seryl-L-cysteinyl-L-threonyl-glycyl-L-seryl-L-prolyl-L-glutaminyl-L-cysteinyl-L-isoleucyl-L-lysyl-L-prolyl-L-cysteinyl-L-lysyl-L-alpha-aspartyl-L-alanyl-glycyl-L-methionyl-L-arginyl-L-phenylalanyl-glycyl-L-lysyl-L-cysteinyl-L-methionyl-L-asparagyl-L-arginyl-L-lysyl-L-cysteinyl-L-histidyl-L-cysteinyl-L-threonyl-L-prolyl-L-lysine (8->28),(14->33),(18->35)-tris(disulfide). Grade: >98%. CAS No. 168147-41-9. Molecular formula: C169H278N54O48S8. Mole weight: 4090.87. | |
| Agitoxin 2 | Agitoxin 2. Group: Biochemicals. Grades: Purified. CAS No. 168147-41-9. Pack Sizes: 10ug. US Biological Life Sciences. | Worldwide |
| Agitoxin-2 from scorpion venom | recombinant, expressed in E. coli, ?98% (SDS-PAGE), lyophilized powder. Group: Fluorescence/luminescence spectroscopy. | |
| AGK2 | ?97% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| AGK2 | AGK2 is a selective SIRT2 inhibitor with an IC50 of 3.5 ?M. AGK2 inhibits SIRT1 and SIRT3 with IC50s of 30 and 91 ?M, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 304896-28-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100578. |  |
| AGK2 | AGK2 is a potent, and selective SIRT2 inhibitor with IC50 of 3.5 μM. Synonyms: AGK-2; AGK 2; 2-cyano-3-(5-(2,5-dichlorophenyl)furan-2-yl)-N-(quinolin-5-yl)acrylamide. Grade: >98%. CAS No. 304896-28-4. Molecular formula: C23H13Cl2N3O2. Mole weight: 434.27. | |
| AGK 2 | AGK 2. Group: Biochemicals. Grades: Purified. CAS No. 304896-28-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AGK7 | AGK2 is a cell-permeable, selective inhibitor of SIRT2 (IC50 = 3.5 μM) that minimally affects either SIRT1 or SIRT3 at 10-fold higher levels. AGK7 is an inactive control to be used in experiments with AGK2. Synonyms: SIRT2 Inhibitor (Inactive Control); 2-cyano-3-[5-(2,5-dichlorophenyl)furan-2-yl]-N-quinolin-8-ylprop-2-enamide. Grade: ≥95%. CAS No. 304896-21-7. Molecular formula: C23H13Cl2N3O2. Mole weight: 434.3. | |
| AGL 2263 | AGL 2263 is an inhibitor of the insulin-like growth factor 1 receptor (IGF-1R; IC50 = 0.43 μM). Synonyms: (E)-2-(3,4-dihydroxybenzoyl)-3-(2-oxo-3H-1,3-benzoxazol-5-yl)prop-2-enenitrile. Grade: ≥98%. CAS No. 638213-98-6. Molecular formula: C17H10N2O5. Mole weight: 322.3. | |
| Aglafoline | Aglafoline, isolated from Aglaia elliptifolia Merr, is a selective PAF-induced platelet aggregation inhibitor. And studies have shown that because aglafoline blocked the high-K+-induced contraction of rat thoracic aorta, it may also possess Ca+- channel b. Synonyms: methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-cyclopenta[b][1]benzofuran-2-carboxylate Aglafoline Methyl rocaglate AGLAFOLIN CHEBI:65374 CMLDBU00002646 143901-35-3 methyl (1R,2R,3S,3aR,8bS)-1,8b-dihydr. CAS No. 143901-35-3. Molecular formula: C28H28O8. Mole weight: 492.52. | |
| Aglain C | Aglain C, an organic alkaloid of natural origins, demonstrates anti-tumor activity, thus possessing potential application in diverse cancer treatment modalities. It elicits apoptosis, or cell death, in malignant cells, and exhibits anti-inflammatory properties. To ascertain its therapeutic value comprehensively, additional examination is warranted. Synonyms: N-((S)-1-((2R,3S,4R,5R,10S)-5,10-dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-3-phenyl-2,3,4,5-tetrahydro-2,5-methanobenzo[b]oxepine-4-carbonyl)pyrrolidin-2-yl)-2-methylbutanamide. Grade: 96%. CAS No. 177468-85-8. Molecular formula: C36H42N2O8. Mole weight: 630.727. | |
| Aglaxiflorin D | Aglaxiflorin D is an alkaloid compound isolated from the leaves of Aglaia abbriviata. Synonyms: (R)-N-((S)-1-((2R,3S,4R,5R,10S)-5,10-dihydroxy-6,8-dimethoxy-2-(4-methoxyphenyl)-3-phenyl-2,3,4,5-tetrahydro-2,5-methanobenzo[b]oxepine-4-carbonyl)pyrrolidin-2-yl)-2-hydroxy-2-methylbutanamide. Grade: 95%. CAS No. 269739-78-8. Molecular formula: C36H42N2O9. Mole weight: 646.727. | |
| Aglepristone | Aglepristone is used as a treatment to induce parturition in ewes and their newborns. A competitive progesterone antagonist for treatment of various progesterone-dependent physiology and pathology conditions, and effective means of terminating pregnancy in most species. Also, it prevents sperm progression toward the oviducts and fertilization in inseminated females. Group: Biochemicals. Grades: Highly Purified. CAS No. 124478-60-0. Pack Sizes: 500mg, 1g. Molecular Formula: C29H37NO2, Molecular Weight: 431.61. US Biological Life Sciences. | Worldwide |
| a-Glucametacin | a-Glucametacin, the acclaimed anti-inflammatory wonder, showcases its unparalleled efficacy in combating a myriad of inflammatory afflictions, notably arthritis, while effectively tackling postoperative discomfort. By impeding the production of prostaglandins and leukotrienes, this remarkable drug alleviates pain and curtails inflammation. Synonyms: 2-[[[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]amino]-2-deoxy-a-D-glucopyranose; a-Glucametacine; a-Glucamethacin; α-D-Glucopyranose, 2-[[[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]amino]-2-deoxy-. CAS No. 871014-84-5. Molecular formula: C25H27ClN2O8. Mole weight: 518.94. | |
| agmatidine | Agmatidine is a compound, finding application in the biomedical realm for studying assorted ailments comprising cancer and inflammation. Its exceptional attributes encompass anti-inflammatory and anti-carcinogenic effects, rendering it a propitious contender for pharmaceutical development. Synonyms: Agmatidine; agm(2)C; N-(4-carbamimidamidobutyl)-4-imino-1-(beta-D-ribofuranosyl)-1,4-dihydropyrimidin-2-amine; 1221169-70-5; RD252EB5W3; CHEBI:64329; DTXSID701029783; Q4692957; N-(4-Carbamimidamidobutyl)-4-imino-1-(beta-D-ribofuranosyl)-1,4-dihydro-2-pyrimidinamine; GUANIDINE, N-(4-((1,4-DIHYDRO-4-IMINO-1-.BETA.-D-RIBOFURANOSYL-2-PYRIMIDINYL)AMINO)BUTYL)-; N-(4-((1,4-DIHYDRO-4-IMINO-1-.BETA.-D-RIBOFURANOSYL-2-PYRIMIDINYL)AMINO)BUTYL)GUANIDINE. Molecular formula: C14H22N7O4. Mole weight: 356.4. | |
| agmatinase | This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is agmatine amidinohydrolase. Other names in common use include agmatine ureohydrolase, and SpeB. This enzyme participates in urea cycle and metabolism of amino groups. Group: Enzymes. Synonyms: agmatine ureohydrolase; SpeB. Enzyme Commission Number: EC 3.5.3.11. CAS No. 37289-16-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4513; agmatinase; EC 3.5.3.11; 37289-16-0; agmatine ureohydrolase; SpeB. Cat No: EXWM-4513. |  |
| agmatine deiminase | The plant enzyme also catalyses the reactions of EC 2.1.3.3 (ornithine carbamoyltransferase), EC 2.1.3.6 (putrescine carbamoyltransferase) and EC 2.7.2.2 (carbamate kinase), thus functioning as a putrescine synthase, converting agmatine and ornithine into putrescine and citrulline, respectively. Group: Enzymes. Synonyms: agmatine amidinohydrolase. Enzyme Commission Number: EC 3.5.3.12. CAS No. 37289-17-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4514; agmatine deiminase; EC 3.5.3.12; 37289-17-1; agmatine amidinohydrolase. Cat No: EXWM-4514. | |
| agmatine kinase | L-Arginine can act as acceptor, but more slowly. Group: Enzymes. Synonyms: phosphagen phosphokinase; ATP:agmatine 4-N-phosphotransferase. Enzyme Commission Number: EC 2.7.3.10. CAS No. 9076-75-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3181; agmatine kinase; EC 2.7.3.10; 9076-75-9; phosphagen phosphokinase; ATP:agmatine 4-N-phosphotransferase. Cat No: EXWM-3181. | |
| agmatine N4-coumaroyltransferase | This enzyme belongs to the family of transferases, to be specific those acyltransferases transferring groups other than aminoacyl groups. Group: Enzymes. Synonyms: p-coumaroyl-CoA-agmatine N-p-coumaroyltransferase; agmatine coumaroyltransferase; 4-coumaroyl-CoA:agmatine 4-N-coumaroyltransferase. Enzyme Commission Number: EC 2.3.1.64. CAS No. 85030-72-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2244; agmatine N4-coumaroyltransferase; EC 2.3.1.64; 85030-72-4; p-coumaroyl-CoA-agmatine N-p-coumaroyltransferase; agmatine coumaroyltransferase; 4-coumaroyl-CoA:agmatine 4-N-coumaroyltransferase. Cat No: EXWM-2244. | |
| Agmatine sulfate | Agmatine sulfate exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide synthesis. It is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor. Uses: Scientific research. Group: Natural products. CAS No. 2482-00-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-101238. | |
| Agmatine Sulfate | Agmatine Sulfate. Group: Biochemicals. Alternative Names: N-(4-aminobutyl)guanidine Sulfate; NIH 11035. Grades: Highly Purified. CAS No. 2482-00-0. Pack Sizes: 1g. Molecular Formula: C5H16N4O4S, Molecular Weight: 228.27. US Biological Life Sciences. | Worldwide |
| Agmatine Sulfate | Agmatine Sulfate. Categories: agmatine sulfate; 2482-00-0. |  CA, FL & NJ |
| Agmatine sulfate endogenous agonist at | Agmatine sulfate endogenous agonist at. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AGMATINE SULFATE ENDOGENOUS AGONIST AT;1-(4-aminobutyl)guanidine;2-(4-aminobutyl)guanidine;(4-Aminobutyl) guanidine;N1-(4-Aminobutyl)guanidine;2-(4-azanylbutyl)guanidine;4-Guanidino-1-butanamine;N-(4-Aminobutyl)guanidine. Product Category: Heterocyclic Organic Compound. CAS No. 306-60-5. Molecular formula: C5H14N4. Mole weight: 130.19146. Density: 1.2. Product ID: ACM306605. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Agmatine Sulfate ≥93% (HPLC) | Agmatine Sulfate ≥93% (HPLC). Group: Biochemicals. Alternative Names: N-(4-aminobutyl)guanidine Sulfate; NIH 11035. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| Agmatine sulfate salt | ?97%, powder. Group: Fluorescence/luminescence spectroscopy. | |
| Agmatine sulfate salt | Agmatine sulfate, the sulfate preparation of Agmatine, is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor. Agmatine displaces clonidine at α2-adrenergic and at imidazoline receptors and produces blockade of the NMDA-receptor associated cation channels. Nutritional supplement in health care products. Uses: Ingredient of health care products. Synonyms: Agmatine sulfate; 1-(4-Aminobutyl)guanidine sulfate; 1-Amino-4-guanidinobutane sulfate salt; Guanidine, (4-aminobutyl)-, sulfate (1:1). Grade: 98%. CAS No. 2482-00-0. Molecular formula: C5H16N4O4S. Mole weight: 228.27. | |
| AGN 192403 hydrochloride | The hydrochloride salt form of AGN 192403, which has been found to show high affinity to imidazoline I1 receptor. Synonyms: AGN-192403 hydrochloride, AGN192403 hydrochloride, AGN 192403 hydrochloride, AGN-192403 HCl; (±)-2-endo-Amino-3-exo-isopropylbicyclo[2.2.1]heptane hydrochloride. Grade: ≥95% by HPLC. CAS No. 1021868-90-5. Molecular formula: C10H19N.HCl. Mole weight: 189.73. | |
| AGN 192403 hydrochloride | AGN 192403 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1021868-90-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| AGN 192836 | AGN 192836 is a potent and selective α2 adrenergic agonist with EC50 of 8.7, 41 and 6.6 nM for α2A, α2B and α2C receptor, respectively. Synonyms: (1H-Imidazol-2-yl)-(5-methyl-2,3-dihydro-benzo[1,4]dioxin-6-yl)-amine; 2-[[(5-Methyl-2,3-dihydro-1,4-benzodioxin)-6-yl]amino]-1H-imidazole. CAS No. 171102-29-7. Molecular formula: C12H13N3O2. Mole weight: 231.25. | |
| Agn 193109 | Agn 193109. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-[2-[5,6-Dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]benzoic Acid; CD 3106. Product Category: Heterocyclic Organic Compound. Appearance: Off-White Solid. CAS No. 171746-21-7. Molecular formula: C28H24O2. Mole weight: 392.49. Purity: 0.96. IUPACName: 4-[2-[5,5-dimethyl-8-(4-methylphenyl)-6H-naphthalen-2-yl]ethynyl]benzoic acid. Density: 1.21 g/cm³. Product ID: ACM171746217. Alfa Chemistry ISO 9001:2015 Certified. | |
| AGN 193109 | AGN 193109 is a retinoid analog, and acts as a specific and highly effective antagonist of retinoic acid receptors (RARs) , with K d s of 2 nM, 2 nM, and 3 nM for RARα , RARβ , and RARγ , respectively. AGN 193109 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. AGN 193109 is the antidote for retinoic acidosis, that ameliorates the skin and mucosal toxicity. Uses: Scientific research. Group: Signaling pathways. CAS No. 171746-21-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00449. | |
| AGN 193109 | AGN 193109 has been found to be a pan-retinoic acid receptor (RAR) antagonist. Synonyms: AGN 193109; AGN193109; AGN-193109; 4-[2-[5,6-Dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]benzoic acid. Grade: ≥97% by HPLC. CAS No. 171746-21-7. Molecular formula: C28H24O2. Mole weight: 392.49. | |
| AGN 193109 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| AGN 193109-d7 | A labeled retinoic acid receptor (RAR) antagonist used for treating chemotherapy and radiation therapy side effects. Group: Biochemicals. Alternative Names: 4- [2- [5, 6-Dihydro-5, 5-dimethyl-8- (4-methylphenyl-d7) -2-naphthalenyl] ethynyl] benzoic Acid; CD 3106-d7. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| AGN 193109-[d7] | AGN 193109-[d7] is the labelled analogue of AGN 193109, which is a retinoic acid receptor (RAR) antagonist used for treating chemotherapy and radiation therapy side effects. Synonyms: AGN 193109 D7; 4-[2-[5,6-Dihydro-5,5-dimethyl-8-(4-methylphenyl-d7)-2-naphthalenyl]ethynyl]benzoic Acid; CD 3106-d7; AGN-193109-d7. Grade: 98%; ≥98% atom D. CAS No. 1216429-25-2. Molecular formula: C28H17D7O2. Mole weight: 399.53. | |
| AGN 193109-d7 Ethyl Ester | Precursor to labeled AGN 193109. Group: Biochemicals. Alternative Names: 4- [2- [5, 6-Dihydro-5, 5-dimethyl-8- (4-methylphenyl-d7) -2-naphthalenyl] ethynyl] benzoic Acid Ethyl Ester. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Agn 193109 ethyl ester | Agn 193109 ethyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-[2-[5,6-Dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]benzoic Acid Ethyl Ester. Product Category: Heterocyclic Organic Compound. Appearance: Pale Yellow Solid. CAS No. 171568-43-7. Molecular formula: C30H28O2. Mole weight: 420.54. Purity: 0.96. IUPACName: ethyl 4-[2-[5,5-dimethyl-8-(4-methylphenyl)-6H-naphthalen-2-yl]ethynyl]benzoate. Product ID: ACM171568437. Alfa Chemistry ISO 9001:2015 Certified. | |
| AGN 193109 Ethyl Ester | Precursor to AGN 193109. Group: Biochemicals. Alternative Names: 4- [2- [5, 6-Dihydro-5, 5-dimethyl-8- (4-methylphenyl) -2-naphthalenyl] ethynyl] benzoic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 171568-43-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| AGN 193109 Ethyl Ester-[d7] | AGN 193109 Ethyl Ester-[d7] is the labelled analogue of AGN 193109 Ethyl Ester, which is a precursor to AGN 193109. Synonyms: AGN 193109-d7 Ethyl Ester; 4-[2-[5,6-Dihydro-5,5-dimethyl-8-(4-methylphenyl-d7)-2-naphthalenyl]ethynyl]benzoic Acid Ethyl Ester. Grade: 98%. CAS No. 1246815-93-9. Molecular formula: C30H21D7O2. Mole weight: 427.59. | |
| AGN 193109 Sodium Salt | A retinoic acid receptor (RAR) antagonist used for treating chemotherapy and radiation therapy side effects. Group: Biochemicals. Alternative Names: 4- [2- [5, 6-Dihydro-5, 5-dimethyl-8- (4-methylphenyl) -2-naphthalenyl] ethynyl] benzoic Acid Sodium Salt; CD 3106 Sodium Salt. Grades: Highly Purified. CAS No. 171746-21-7(freebase). Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| AGN 193109 Sodium Salt | AGN 193109 is a potent antagonist of retinoic acid receptors (RARs, Kd = 2, 2, and 3 nM for RARα, β, and γ, respectively). Synonyms: 4-[2-[5,6-dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]-benzoic acid monosodium salt; CD 3106 Sodium Salt; Benzoic acid, 4-[2-[5,6-dihydro-5,5-dimethyl-8-(4-methylphenyl)-2-naphthalenyl]ethynyl]-, sodium salt (1:1); sodium 4-((5,5-dimethyl-8-(p-tolyl)-5,6-dihydronaphthalen-2-yl)ethynyl)benzoate. Grade: 95%. Molecular formula: C28H23NaO2. Mole weight: 414.47. | |
| AGN 194078 | AGN 194078, is a selective RARα agonist with a Kd and EC50 of 3 and 112 nM, respectively. Synonyms: AGN-194078. CAS No. 321995-62-4. Molecular formula: C22H23F2NO4. Mole weight: 403.42. | |
| AGN194204 | AGN194204 (IRX4204) is an orally active and selective RXR agonist with Kd values 0.4 nM, 3.6 nM and 3.8 nM and EC50s of 0.2 nM, 0.8 nM and 0.08 nM for RXR?, RXR? and RXR?, respectively. AGN194204 is inactive against RAR. AGN194204 has anti-inflammatory and anticarcinogenic actions[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IRX4204; NRX194204; VTP 194204. CAS No. 220619-73-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-13717. | |
| AGN 194310 | AGN 194310 (VTP-194310) is a high affinity, potent and selective retinioic acid receptors (RARs) pan-antagonist with Kd values of 3 nM, 2 nM, 5 nM for RAR?, RAR?, RAR?, respectively[1][2]. AGN 194310 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VTP-194310. CAS No. 229961-45-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-16681. | |
| AGN 194310 | A high affinity pan-RAR antagonist (AGN194310, K(d) for binding to RARs=2-5 nM) inhibited colony formation (by 50%) by all three lines at 16-34 nM, and led to a transient accumulation of flask-cultured cells in G1 followed by apoptosis. AGN194310 is 12-22 fold more potent than all-trans retinoic acid (ATRA) against cell lines and also more potent in inhibiting the growth of primary prostate carcinoma cells. The administration of all-trans retinoic acid to VAD mice resulted in a transient reduction in NF-kappaB activity and, conversely, a single dose of the RAR-pan-antagonist, AGN 194310, administered to control mice, led to a marked, transient induction of whole-body luminescence. Mice were treated with AGN194310, a synthetic retinoid that antagonises the physiological function of the three RAR isotypes (alpha, beta, gamma) but does not interact with RXRs. Analyses of the granulocytic lineage using Gr-1, c-Kit and CD11b antibodies, demonstrated that granulocyte numbers were strikingly increased across haemopoietic compartments in all AGN194310-treated mice. A significant increase in the frequency of progenitor cells containing granulocytes was observed in the bone marrow of mice following treatment with AGN194310. Synonyms: AGN194310; AGN-194310; VTP194310; VTP 194310; VTP-194310. Grade: >98%. CAS No. 229961-45-9. Molecular formula: C28H24O2S. Mole weight: 424.55. | |
| AGN 195183 | RX-195183 is an RARα agonist (Kd=3 nM) with potential antineoplastic activity, modulating the transcription of genes responsible for cell differentiation and proliferation. Uses: Rarα agonist. Synonyms: IRX5183; IRX-5183; IRX 5183; NRX195183; NRX-195183; NRX 195183; VTP-195183; VTP195183; VTP 195183; AGN-195183; AGN195183; AGN195183.; 4-[(4-chloro-3-hydroxy-5,5,8,8-tetramethyl-6,7-dihydronaphthalene-2-carbonyl)amino]-2,6-difluorobenzoic acid. Grade: ≥98%. CAS No. 367273-07-2. Molecular formula: C22H22ClF2NO4. Mole weight: 437.87. | |
| AGN 196996 | AGN 196996 is a potent and selective antagonist of RARα. It has been reported to selectively bind to RARs (retinoic acid receptors) for RARα, RARβ and RARγ. It can inhibit the gene transcription activity which induced by ATRA and other RAR agonists. It shows no activity in transactivation assays, but instead block the gene transcriptional activity induced by ATRA and other RAR agonists. Grade: >98%. CAS No. 958295-17-5. Molecular formula: C24H20BrNO5. Mole weight: 482.32. | |
| AGN 203818 | AGN 203818 is an α2-adrenergic receptor antagonist that can be used to treat fibromyalgia-associated pain. Synonyms: 2H-Imidazole-2-thione, 4-[1-(2,3-dimethylphenyl)ethyl]-1,3-dihydro-, hydrochloride (1:1); 4-[1-(2,3-Dimethylphenyl)ethyl]-1,3-dihydro-2H-imidazole-2-thione hydrochloride (1:1); AGN203818; AGN-203818; AGN 203818 hydrochloride. Grade: ≥95%. CAS No. 1021954-16-4. Molecular formula: C13H16N2S.HCl. Mole weight: 268.81. | |
| AGN 205327 | AGN 205327 is a potent synthetic RARs agonist with EC50 of 3766, 734, 32 nM for RARα, β, γ respectively. Synonyms: AGN205327; AGN-205327. Molecular formula: C24H26N2O3. Mole weight: 390.47. | |
| AGN 205728 | AGN 205728 is a potent and selective RARγ antagonist and has no inhibiton on RARα and RARβ. Synonyms: AGN 205728; AGN205728; AGN-205728. Grade: >98%. CAS No. 859498-05-8. Molecular formula: C29H27NO3. Mole weight: 437.53. | |
| AGN 210676 | AGN 210676 is a small molecule prostaglandin E2 receptor agonist under development for the treatment of glaucoma and ocular hypertension. Synonyms: Simenepag; AGN-210676; AGN210676; 5-((((r)-1-(4-((s)-1-hydroxyhexyl)phenyl)-5-oxopyrrolidin-2-yl)methoxy)methyl)thiophene-2-carboxylic acid. Grade: 95%. CAS No. 910562-15-1. Molecular formula: C23H29NO5S. Mole weight: 431.55. | |
| Agnuside | Agnuside is used in the study of asthma, inflammation, and angiogenic diseases. Agnuside is an orally active compound that can be extracted from Vitex negundo [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Agnoside. CAS No. 11027-63-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N2518. | |
| Agnuside | Agnuside. Group: Biochemicals. Alternative Names: Agnoside; Buddlejoside A. Grades: Plant Grade. CAS No. 11027-63-7. Pack Sizes: 10mg. Molecular Formula: C22H26O11, Molecular Weight: 466.435. US Biological Life Sciences. | Worldwide |
| Agomelatine | Agomelatine. Group: Biochemicals. Alternative Names: N-[2-(7-Methoxynaphth-1-yl)ethyl]acetamide; S20098. Grades: Highly Purified. CAS No. 138112-76-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C15H17NO2. US Biological Life Sciences. | Worldwide |
| Agomelatine | Agomelatine (S-20098) is a specific agonist of MT1 and MT2 receptors with K i s of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively [1]. Agomelatine is a selective 5-HT2C receptor antagonist with pK i s of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively [2]. Uses: Scientific research. Group: Natural products. Alternative Names: S-20098. CAS No. 138112-76-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17038. | |
| Agomelatine | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H17NO2. CAS No. 138112-76-2. Prepack ID 54855684-1g. Molecular Weight 243.3. See USA prepack pricing. |  |
| Agomelatine-d6 | Agomelatine-d6 is labelled Agomelatine (A430000) which is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human (h)5-hydroxytryptamine (5-HT)2C receptors, respectively. Group: Biochemicals. Grades: Highly Purified. CAS No. 1079389-42-6. Pack Sizes: 1mg. Molecular Formula: C15H11D6NO2, Molecular Weight: 249.34. US Biological Life Sciences. | Worldwide |
| Agomelatine hydrochloride | Agomelatine hydrochloride (S-20098 hydrochloride) is a specific agonist of MT1 and MT2 receptors with K i s of 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2, respectively [1]. Agomelatine hydrochloride is a selective 5-HT2C receptor antagonist with pK i s of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively [2]. Uses: Scientific research. Group: Natural products. Alternative Names: S-20098 hydrochloride. CAS No. 1176316-99-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17038A. | |
| Agomelatine impurity 13 | Agomelatine impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-(7-methoxynaphthalen-1-yl)ethan-1-aminehydrochloride. CAS No. 139525-77-2. Molecular formula: C13H15NO. Mole weight: 201.26. Catalog: APB139525772. | |
| Agomelatine Impurity 15 | Agomelatine Impurity 15. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-(2-(7-hydroxynaphthalen-1-yl)ethyl)acetamide. CAS No. 152302-45-9. Molecular formula: C14H15NO2. Mole weight: 229.27. Catalog: APB152302459. | |
| Agomelatine Impurity 2 | An analogue of Agomelatine. Synonyms: (E)-1-[2-(acetylamino)ethylidene]; (E)-N-(2-(7-methoxy-3,4-dihydronaphthalen-1(2H)-ylidene. Grade: > 95%. CAS No. 178677-39-9. Molecular formula: C15H19NO2. Mole weight: 245.32. | |
| Agomelatine Impurity 26 | Agomelatine Impurity 26. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1,3-bis(2-(7-methoxynaphthalen-1-yl)ethyl)urea. CAS No. 185421-27-6. Molecular formula: C27H28N2O3. Mole weight: 428.21. Catalog: APB185421276. | |
| Agomelatine Impurity 31 | Agomelatine Impurity 31. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ethyl 4-(4-methoxyphenyl)-4-oxobutanoate. CAS No. 15118-67-9. Molecular formula: C13H16O4. Mole weight: 236.10. Catalog: APB15118679. | |
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