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| Product | Description | |
|---|---|---|
| BTdCPU | BTdCPU is a potent heme regulated inhibitor kinase (HRI) activator that promotes eIF2? phosphorylation and induces apoptosis in Dexamethasone (HY-14648) (Dex)-resistant cancer cells. BTdCPU can be used in the study of cancers such as multiple myeloma and Dex-resistant multiple myeloma[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1257423-87-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118266. |  |
| BTEM-PPV | BTEM-PPV. Group: Organic light-emitting diode (oled) materials. Alternative Names: POLY(2 5-BIS(1 4 7 10-TETRAOXAUNDECYL)-&; btem-ppv; BTEM-PPV,Poly[2,5-bis(triethoxymethoxy)-1,4-phenylenevinylene],Poly(2,5-bis(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)-1,4-phenylenevinylene). CAS No. 221244-49-1. Mole weight: (C22< / sub>H34< / sub>O8< / sub>) n. |  |
| b-tert-Butyl-D-alanine 99+% | b-tert-Butyl-D-alanine 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 88319-43-1. Pack Sizes: 100mg, 250mg, 1g, 5g. US Biological Life Sciences. |  Worldwide |
| b-tert-Butyl-DL-alanine 98+% (NMR) | b-tert-Butyl-DL-alanine 98+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| b-tert-Butyl-L-alanine 98+% ( | b-tert-Butyl-L-alanine 98+% (. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| BTEX - Clay 1 | pkg of 30 g. Group: Certified reference materials (crms). |  |
| BTEX/GRO - Loamy Clay 2 | certified reference material, pkg of 30 g. Group: Certified reference materials (crms). | |
| BTEX/GRO - Soil | pkg of 30 g. Group: Certified reference materials (crms). | |
| BTEX in Water - AK Methods | certified reference material. Group: Certified reference materials (crms). | |
| BTEX in Water - AK - PT | Proficiency Testing Material. Group: Waste water. | |
| BTEX - Loamy Sand 1 | certified reference material, pkg of 30 g. Group: Certified reference materials (crms). | |
| BTEX/MTBE in Soil | certified reference material. Group: Certified reference materials (crms). | |
| BTEX - Silt Loam 1 | pkg of 30 g. Group: Certified reference materials (crms). | |
| BTEX Solution | analytical standard. Group: Application areas. | |
| BTFFH | BTFFH. Group: Biochemicals. Alternative Names: Fluoro-N, N, N', N'-bis (tetramethylene) formamidinium hexafluorophosphate; Fluoro-dipyrrolidinocarbenium hexafluorophosphate. Grades: Highly Purified. CAS No. 164298-25-3. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C9H16F7N2P. US Biological Life Sciences. | Worldwide |
| BTFFH | BTFFH. Synonyms: 1-(Fluoro-1-pyrrolidinylmethylene)pyrrolidinium Hexafluorophosphate; Fluoro-N,N,N',N'-bis(tetramethylene)formamidinium Hexafluorophosphate; Fluoro-dipyrrolidinocarbenium hexafluorophosphate; Pyrrolidinium,1-(fluoro-1-pyrrolidinylmethylene)-,hexafluorophosphate(1-); Bis(tetramethylene fluoroformamidinium hexafluorophosphate; Fluoro-dipyrrolidinocarbenium hexafluorophosphate. Grade: 98% (HPLC). CAS No. 164298-25-3. Molecular formula: C9H16F7N2P. Mole weight: 316.20. |  |
| BTI-A-404 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BTK, active, His tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| BTK active human | recombinant, expressed in baculovirus infected Sf9 cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| BTK IN-1 | BTK IN-1 is a non-covalently binding inhibitor of Bruton's tyrosine kinase (BTK). Synonyms: SNS062-analog; SNS-062 analog; N-(1-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl)-2-((3-chlorophenyl)amino)acetamide. Grade: 98%. CAS No. 1270014-40-8. Molecular formula: C19H21ClN6O. Mole weight: 384.86. | |
| BTK-IN-5 | BTK-IN-5 is a covalent BTK inhibitor for the treatment of cardiovascular disease, respiratory disease, inflammation and diabetes. Synonyms: (S)-N-((2S,3R)-3-(tert-butoxy)-1-(((R)-3-(4-cyanophenyl)-1-(methylamino)-1-oxopropan-2-yl)amino)-1-oxobutan-2-yl)-2-methyloxirane-2-carboxamide. CAS No. 2145152-06-1. Molecular formula: C23H32N4O5. Mole weight: 444.52. | |
| Btk inhibitor 1 | Btk inhibitor 1 is a pyrazolo[3,4-d]pyrimidine derivative as a Btk kinase inhibitor. Synonyms: Btk inhibitor 1. Grade: >98%. CAS No. 1412418-47-3. Molecular formula: C22H22N6O. Mole weight: 386.45. | |
| BTK inhibitor 10 | BTK inhibitor 10, a potent and orally active BTK inhibitor, has a potential for rheumatoid arthritis treatment. (Extracted from patent WO2018145525, example 33). Synonyms: BTK-030; N-[3-({6-[4-(4-Morpholinyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)phenyl]acrylamide; 2-Propenamide, N-[3-[[6-[4-(4-morpholinyl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]-. Grade: 98%. CAS No. 2241732-30-7. Molecular formula: C25H23N5O3. Mole weight: 441.48. | |
| BTK inhibitor 13 | BTK inhibitor 13 is a potent and selective BTK inhibitor with an IC50 of 1.2 nM. Synonyms: N-{3-[5-(N-Acryloyl-N-methylglycyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-5-fluoro-2-methylphenyl}-4-cyclopropylbenzamide; Benzamide, 4-cyclopropyl-N-[5-fluoro-2-methyl-3-[5-[2-[methyl(1-oxo-2-propen-1-yl)amino]acetyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]phenyl]-. Grade: 98%. CAS No. 2376726-26-8. Molecular formula: C29H26FN5O3. Mole weight: 511.55. | |
| BTK inhibitor 19 | BTK inhibitor 19 is a highly selective and covalent BTK inhibitor with an IC50 of 2.7 nM. Synonyms: 1H-Imidazole-5-carboxamide, 1-amino-2-[(2S)-1-(1-oxo-2-propen-1-yl)-2-piperidinyl]-4-[4-[[[4-(trifluoromethyl)-2-pyridinyl]amino]carbonyl]phenyl]-; (S)-2-(1-acryloylpiperidin-2-yl)-1-amino-4-(4-((4-(trifluoromethyl)pyridin-2-yl)carbamoyl)phenyl)-1H-imidazole-5-carboxamide. CAS No. 2557174-19-1. Molecular formula: C25H24F3N7O3. Mole weight: 527.50. | |
| BTK inhibitor 1 (Compound 27) | BTK inhibitor 1 is an inhibitor of BTK with IC50 of 0.11 nM for Btk and inhibits B cell activation in hWB with IC50 of 2 nM. Synonyms: DC20199; Compound 27. Grade: ≥98%. CAS No. 2230724-66-8. Molecular formula: C24H23FN8O2. Mole weight: 474.49. | |
| Btk inhibitor 1 R enantiomer | Btk inhibitor 1 R enantiomer is a pyrazolo[3,4-d]pyrimidine derivative as a Btk kinase inhibitor. Synonyms: 3-(4-phenoxyphenyl)-1-[(3R)-3-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine; (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine; 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(4-phenoxyphenyl)-1-(3R)-3-piperidinyl-. Grade: ≥98% by HPLC. CAS No. 1022150-12-4. Molecular formula: C22H22N6O. Mole weight: 386.45. | |
| Btk inhibitor 1 R enantiomer hydrochloride | Btk inhibitor 1R enantiomer Hcl is a pyrazolo[3,4-d]pyrimidine derivative as a Btk kinase inhibitor. Synonyms: Btk inhibitor 1 R enantiomer hydrochloride. Grade: >98%. CAS No. 1553977-42-6. Molecular formula: C22H23ClN6O. Mole weight: 422.91. | |
| BTK inhibitor 2 | Bruton's tyrosine kinase (BTK), also known as tyrosine-protein kinase BTK, is an enzyme that in humans is encoded by the BTK gene. BTK is a kinase that plays a crucial role in B-cell development. Btk inhibitor 2 is a BTK inhibitor. Grade: ≥98%. CAS No. 1558036-85-3. Molecular formula: C24H25N5O3. Mole weight: 431.49. | |
| BTL | BTL was isolated from Bacillus subtilis B-TL2. BTL shows relatively low identity to other antimicrobial peptides from bacteria. The peptide exhibited strong inhibitory activity against mycelial growth of Bipolaris maydis, Alternaria brassicae, Aspergillus niger, Cercospora personata. | |
| BTM-1086 | BTM-1086 is a potent gastric secretory inhibitor and an anti-ulcer agent. Synonyms: BTM1086; cis-2,3-dihydro-3-[(4-methylpiperazinyl)methyl]-2-phenyl-1,5-benzothiazepin-4(5H)-one. CAS No. 72293-17-5. Molecular formula: C21H25N3OS. Mole weight: 367.51. | |
| BTO-1 | BTO-1 is a benzothiazolo-N-oxide Plk1 inhibitor. BTO-1 is primarily used for phosphorylation and dephosphorylation applications. Synonyms: 5-Cyano-7-nitro-3-oxy-benzothiazole-2-carboxylic acid amide. Grade: ≥97%. CAS No. 40647-02-7. Molecular formula: C9H4N4O4S. Mole weight: 264.22. | |
| BTO-1 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| BTO-1 | BTO-1 is a Polo-like kinase (Plk) inhibitor. BTO-1 is primarily used for phosphorylation and dephosphorylation applications. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BTO-1; 5-cyano-7-nitro-3-oxy-benzothiazole-2-carboxylic acid amide; HMS3260F21; HMS3229L17; 5-Cyano-7-nitro-2-benzothiazolecarboxamide-3-oxide. Product Category: Inhibitors. CAS No. 40647-02-7. Molecular formula: C9H4N4O4S. Mole weight: 264.22. Purity: ≥97%. IUPACName: 5-cyano-7-nitro-3-oxido-1,3-benzothiazol-3-ium-2-carboxamide. Canonical SMILES: C1=C(C=C(C2=C1[N+](=C(S2)C(=O)N)[O-])[N+](=O)[O-])C#N. Product ID: ACM40647027. Alfa Chemistry ISO 9001:2015 Certified. Categories: BTR-152. |  |
| BTP1 | BTP1. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-(3-(9H-Carbazol-9-yl)phenyl)benzo[4,5]thieno[2,3-b]pyridine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 1421599-23-6. Molecular formula: C29H18N2S. Mole weight: 426.53 g/mol. Product ID: ACM1421599236. Alfa Chemistry ISO 9001:2015 Certified. Categories: BtpA protein. | |
| BTQBT (purified by sublimation) | BTQBT (purified by sublimation). Group: other material building blockselectronic materials organic field effect transistor (ofet) materials. Alternative Names: 4,8-Bis(1,3-dithiol-2-ylidene)-4H,8H-benzo[1,2-c:4,5-c']bis[1,2,5]thiadiazole (purified by sublimation) Bis(1,2,5-thiadiazolo)-p-quinobis(1,3-dithiole) (purified by sublimation). CAS No. 135704-54-0. Molecular formula: 396.55. Mole weight: C12H4N4S6. InChI=1S/C12H4N4S6/c1-2-18-11 (17-1)5-7-9 (15-21-13-7)6 (12-19-3-4-20-12)10-8 (5)14-22-16-10/h1-4H. ABMLGFPCLXTCEI-UHFFFAOYSA-N. >98.0%(N). | |
| BTQBT, (purified by sublimation) | BTQBT, (purified by sublimation). Group: Semiconducting materials. CAS No. 135704-54-0. | |
| BTQBT (purified by sublimation), 98% | BTQBT (purified by sublimation), 98%. Group: Organic solar cell (opv) materials. CAS No. 135704-54-0. | |
| BTR-1 | BTR-1 is an active anti-cancer agent, causes S phase arrest, and affects DNA replication in leukemic cells. BTR-1 activates apoptosis and induces cell death. Synonyms: 3-ethyl-5-(phenylmethylidene)-2-sulfanylidene-1,3-thiazolidin-4-one. Grade: 99%. CAS No. 18331-34-5. Molecular formula: C12H11NOS2. Mole weight: 249.35. | |
| BTR-1 | BTR-1 is an active anti-cancer agent, causes S phase arrest, and affects DNA replication in leukemic cells. BTR-1 activates apoptosis and induces cell death [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 18331-34-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111617. | |
| Btr I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 60°C in a total reaction volume of 50 μl. Applications: After 3-fold overdigestion with enzyme 80% of dna fragments can be ligated. of these 90% can be recut. Group: Restriction Enzymes. Purity: 100U; 500U. CAC↑GTC GTG↓CAG. Activity: 2000-5000u.a./ml. Appearance: 10 X SE-buffer O, BSA. Storage: -20°C. Form: Liquid. Source: Bacillus stearothermophilus SE-U62. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; and 50% glycerol. Cat No: ET-1093RE. |  |
| b-Trisaccharide-APE-HAS | b-Trisaccharide-APE-HAS. Synonyms: Blood Group b trisaccharide-APE-HAS. | |
| b-Trisaccharide-GEL | b-Trisaccharide-GEL. Synonyms: Blood Group b trisaccharide-GEL. | |
| b-Tropine 99+% | b-Tropine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| BTS | A potent inhibitor of skeletal muscle Ca2+-stimulated myosin S1 ATPase (IC50 approx. 5uM) activity. Reversible blocks the gliding motility. Also weakens myosin's interaction with F-actin. Does not affect platelet myosin II. Synonyms: BTS; BnNHTs; N-Benzyl-p-toluenesulfonamide; N-Tosylbenzylamine. Grade: >98%. CAS No. 1576-37-0. Molecular formula: C14H15NO2S. Mole weight: 261.34. | |
| BTS | BTS (N-Benzyl-p-toluenesulfonamide) is a potent and selective inhibitor of skeletal muscle myosin II subfragment 1 (S1) ATPase activity, with an IC 50 s of ~5 μM for actin- and Ca 2+ -stimulated myosin S1 ATPase. BTS specifically inhibits the contraction of fast skeletal muscle fibers [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: N-Benzyl-p-toluenesulfonamide; N-Tosylbenzylamine. CAS No. 1576-37-0. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-16690. | |
| BTS 44595 | BTS 44595. Uses: For analytical and research use. Group: Pesticides & metabolites; stable isotope labelled compounds; pesticides & metabolites. Alternative Names: BTS 44595, Prochloraz desimidazole-amino, N-Propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]urea,Urea, N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-, BTS 44595. CAS No. 139520-94-8. Pack Sizes: 10MG. IUPAC Name: 1-propyl-1-[2-(2,4,6-trichlorophenoxy)ethyl]urea. Molecular formula: C12H15Cl3N2O2. Mole weight: 325.62. Catalog: APS139520948. SMILES: CCCN(CCOc1c(Cl)cc(Cl)cc1Cl)C(=O)N. Format: Neat. Shipping: Room Temperature. | |
| BTS 44595 | BTS 44595 is a metabolite of Prochloraz, an effective fungicide against cereal powdery mildew. Synonyms: 1-Propyl-1-[2-[2,4,6-tri-chlorophenoxy]ethyl]-urea; N-Propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]urea; Prochloraz Metabolite BTS 44595; Urea, N-propyl-N-[2-(2,4,6-trichlorophenoxy)ethyl]-. Grade: ≥95%. CAS No. 139520-94-8. Molecular formula: C12H15Cl3N2O2. Mole weight: 325.62. | |
| BTS 54-505 hydrochloride | BTS 54-505 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 84484-78-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BTSA1 | BTSA1 is a potent, high affinity and orally active BAX activator with an IC50 of 250 nM and an EC50 of 144 nM. BTSA1 binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 314761-14-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123054. | |
| BTSA1 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| BTSA1 | BTSA1 is a BAX activator that binds to the N-terminal activation site with high affinity and specificity induces conformational changes to BAX leading to BAX-mediated apoptosis. It effectively promotes apoptosis in leukemia cell lines and patient samples while sparing healthy cells. Synonyms: BTSA1. Grade: ≥98%. CAS No. 314761-14-3. Molecular formula: C21H14N6OS2. Mole weight: 430.51. | |
| BTT 3033 | BTT 3033 is a selective inhibitor of α2β1 integrin (EC50 = 130 nM for α2β1 binding to collagen I) that binds to the α2I domain. BTT 3033 inhibits platelet aggregation to collagen I coated capillaries under flow, and also inhibits binding of α2-expressing CHO cells to collagen I under shear stress conditions. Synonyms: BTT-3033; BTT 3033; BTT3033; 1-(4-Fluorophenyl)-N-methyl-N-[4[[(phenylamino)carbonyl]amino]phenyl]-1H-pyrazole-4-sulfonamide. Grade: ≥98% by HPLC. CAS No. 1259028-99-3. Molecular formula: C23H20FN5O3S. Mole weight: 465.5. | |
| BTT 3033 | BTT 3033. Group: Biochemicals. Grades: Purified. CAS No. 1259028-99-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BTT-3033 | BTT-3033 is an orally active conformation-selective inhibitor of ?2?1 (EC50: 130 nM) by binding to the ?2I domain. BTT-3033 inhibits platelet binding to collagen ? and cell proliferation, and induces cell apoptosis. BTT-3033 can be used in the research of prostate cancer, inflammation and cardiovascular disease[1][2][4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1259028-99-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-110112. | |
| BTT-4 | BTT-4. Uses: Designed for use in research and industrial production. Product Category: Organic Photovoltaic (OPV). CAS No. 1908506-93-3. Product ID: ACM1908506933. Alfa Chemistry ISO 9001:2015 Certified. Categories: BTR-40. | |
| BTTAA | BTTAA is a Cu(I)-stabilizing ligand, whch performs potently with ubiquitin Glu18AzF. Uses: Scientific research. Group: Signaling pathways. CAS No. 1334179-85-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100486. | |
| BTTP | BTTP is a tris(triazolylmethyl)amine-based ligand. BTTP can accelerate the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC), the prototypical reaction in click chemistry[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1341215-17-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W615104. | |
| BTX161 | BTX161 is a thalidomide analogue and a potent CKIα degrader. BTX161 mediates CKIα degradation better than lenalidomide in human AML cells and activates DNA damage response (DDR) and p53, while stabilizing the p53 antagonist MDM2. Synonyms: (S)-3-(4-Methyl-1-oxoisoindolin-2-yl)azepane-2,7-dione. Grade: ≥98%. CAS No. 2052301-24-1. Molecular formula: C15H16N2O3. Mole weight: 272.30. | |
| BTX-A51 | BTX-A51 (Casein Kinase inhibitor A51) is a potent and orally active casein kinase 1α (CK1α) inhibitor. BTX-A51 induces leukemia cell apoptosis , and has potent anti-leukemic activities [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Casein Kinase inhibitor A51. CAS No. 2079068-74-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123954. | |
| BTYNB | BTYNB is a potent and selective inhibitor of the binding of IMP1 to c-Myc mRNA (IC50=5 μM). BTYNB is selective and effective for IMP1-positive cancer cell lines. Synonyms: 2-{[(E)-(5-Bromothiophen-2-Yl)Methylidene]Amino}Benzamide. Grade: 98%. CAS No. 304456-62-0. Molecular formula: C12H9BrN2OS. Mole weight: 309.18. | |
| BTYNB | BTYNB is a potent and selective inhibitor of IMP1 binding to c-Myc mRNA (IC50=5 ?M). BTYNB exhibits selectivity and effectiveness against IMP1-postive cancer cell lines. BTYNB can be used for cancer research[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 304456-62-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-124447. | |
| BTYNB isomer | A ring-closed isomer of BTYNB and potential angionesis inhibitor. Synonyms: BTYNB IMP1 inhibitor isomer; 2-(5-Bromothiophen-2-yl)-2,3-dihydroquinazolin-4(1H)-one. Grade: 99%. CAS No. 1262217-87-7. Molecular formula: C12H9BrN2OS. Mole weight: 309.18. | |
| Btz043 | BTZ043 is an inhibitor of decaprenyl-phosphoribose-epimerase (DprE1), with MICs of of 2.3 nM and 9.2 nM for M. tuberculosis H37Rv and Mycobacterium smegmatis, respectively. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BTZ043;BTZ043 raceMate;2-[(2S)-2-Methyl-1,4-dioxa-8-azaspiro[4.5]decan-8-yl]-8-nitro-6-trifluoromethyl-4H-1,3-benzothiazin-4-one;BTZ 10526043;PBTZ 169. Product Category: Inhibitors. Appearance: Solid. CAS No. 1161233-85-7. Molecular formula: C17H16F3N3O5S. Mole weight: 431.3862496. Purity: 0.9975. Canonical SMILES: O=C1N=C(N(CC2)CCC32OC[C@H](C)O3)SC4=C([N+]([O-])=O)C=C(C(F)(F)F)C=C14. Density: 1.68. Product ID: ACM1161233857. Alfa Chemistry ISO 9001:2015 Certified. | |
| BTZ043 | The new antitubercular drug candidate 2-[2-S-methyl-1,4-dioxa-8-azaspiro[4.5]dec-8-yl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one (BTZ043) targets the DprE1 (Rv3790) subunit of the enzyme decaprenylphosphoryl-beta-d-ribose 2'-epimerase. To monitor the potential development of benzothiazinone (BTZ) resistance, a total of 240 sensitive and multidrug-resistant Mycobacterium tuberculosis clinical isolates from four European hospitals were surveyed for the presence of mutations in the dprE1 gene and for BTZ susceptibility. All 240 strains were susceptible, thus establishing the baseline prior to the introduction of BTZ043 in clinical trials. Synonyms: BZT043; BZT 043; BZT-043; 2-[2-S-methyl-1,4-dioxa-8-azaspiro[4.5]dec-8-yl]-8-nitro-6-(trifluoromethyl)-4H-1,3-benzothiazin-4-one. CAS No. 1161233-85-7. Molecular formula: C17H16F3N3O5S. Mole weight: 431.39. | |
| BTZ043 Racemate | BTZ043 racemate is a decaprenylphosphoryl-β-D-ribose 2'-epimerase (DprE1) inhibitor acting as a new antimycobacterial agent that kill Mycobacterium tuberculosis. Synonyms: BTZ 043 Racemate; BTZ-043 Racemate; 2-(2-methyl-1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-8-nitro-6-(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one. Grade: >98%. CAS No. 957217-65-1. Molecular formula: C17H16F3N3O5S. Mole weight: 431.39. | |
| BTZ-N3 | BTZ-N3, a electron deficient nitroaromatic compound, is a potent and selective anti-TB drug candidate. Synonyms: BTZ-N3; BTZN3; BTZ N3. (S)-8-azido-2-(2-methyl-1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-6-(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one. Grade: >98%. CAS No. 1839081-05-8. Molecular formula: C17H16F3N5O3S. Mole weight: 427.40. | |
| BTZO 1 | BTZO 1 is a macrophage migration inhibitory factor (MIF) binder (Kd = 68.6 nM). BTZO 1 activates antioxidant response element (ARE)-mediated gene expression and inhibits oxidative stress-induced cardiomyocyte apoptosis in vitro. Uses: Cardioprotective. Synonyms: BTZO1; BTZO 1; BTZO-1; 2-(2-Pyridinyl)-4H-1,3-benzothiazin-4-one. Grade: ≥99% by HPLC. CAS No. 99420-15-2. Molecular formula: C13H8N2OS. Mole weight: 240.28. | |
| BTZO 1 | BTZO 1. Group: Biochemicals. Grades: Purified. CAS No. 99420-15-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| BTZO-1 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
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