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| Product | Description | |
|---|---|---|
| Belumosudil Impurity 3 | Belumosudil Impurity 3. Uses: For analytical and research use. Alternative Names: 5-nitroso-1H-indazole. Molecular formula: C7H5N3O. Mole weight: 147.13. Catalog: APB03739. |  |
| Belumosudil Impurity 4 | Belumosudil Impurity 4. Uses: For analytical and research use. Alternative Names: N-(1H-indazol-5-yl)hydroxylamine. Molecular formula: C7H7N3O. Mole weight: 149.15. Catalog: APB03740. | |
| Belumosudil Impurity 5 | Belumosudil Impurity 5. Uses: For analytical and research use. Alternative Names: 1,2-di(1H-indazol-5-yl)diazene. Molecular formula: C14H10N6. Mole weight: 262.27. Catalog: APB03737. | |
| Belumosudil Impurity 6 | Belumosudil Impurity 6. Uses: For analytical and research use. Alternative Names: 1,2-di(1H-indazol-5-yl)hydrazine. Molecular formula: C14H12N6. Mole weight: 264.29. Catalog: APB03736. | |
| Belumosudil Impurity 7 | Belumosudil Impurity 7. Uses: For analytical and research use. Alternative Names: 1,2-di(1H-indazol-5-yl)diazene oxide. Molecular formula: C14H10N6O. Mole weight: 278.27. Catalog: APB03733. | |
| Belumosudil Impurity 8 | Belumosudil Impurity 8. Uses: For analytical and research use. Alternative Names: N-(2-carbamoylphenyl)-3-(2-((2-carbamoylphenyl)amino)-2-oxoethoxy)benzamide. Molecular formula: C23H20N4O5. Mole weight: 432.43. Catalog: APB03735. | |
| Belumosudil Impurity 9 | Belumosudil Impurity 9. Uses: For analytical and research use. Alternative Names: 3-(4-((1H-indazol-5-yl)amino)quinazolin-2-yl)phenol. Molecular formula: C21H15N5O. Mole weight: 353.38. Catalog: APB03734. | |
| Belumosudil mesylate | Belumosudil is an orally bioavailable inhibitor of ROCK-II that is greater than 200-fold selective over ROCK-I (IC50s = 105 nM and 24 μM, respectively). Alternative Names: KD025 mesylate; SLx-2119 mesylate; 2-(3-(4-(1H-indazol-5-ylamino)quinazolin-2-yl)phenoxy)-N-(propan-2-yl)acetamide methanesulfonate (1:1). CAS No. 2109704-99-4. Molecular formula: C27H28N6O5S. Mole weight: 548.62. |  |
| Belumosudil mesylate | Belumosudil mesylate (KD025 mesylate) is a selective inhibitor of ROCK2 with IC50s of 105 nM and 24 μM for ROCK2 and ROCK1, respectively. Anti-fibrotic properties[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KD025 mesylate; SLx-2119 mesylate. CAS No. 2109704-99-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15307A. |  |
| Belumosudil Mesylate | Belumosudil Mesylate. Uses: For analytical and research use. Alternative Names: 2-(3-(4-((1H-indazol-5-yl)amino)quinazolin-2-yl)phenoxy)-N-isopropylacetamide methanesulfonate. CAS No. 2109704-99-4. Molecular formula: C26H24N6O2. Mole weight: 452.51. Catalog: APB2109704994. | |
| Belvarafenib | Belvarafenib is a potent and selective pan-RAF kinase inhibitor with IC50 of 41 nM, 7 nM and 2 nM for BRAF WT, BRAF(V600E) and CRAF kinases, respectively. Alternative Names: GDC5573; RG6185; HM95573. CAS No. 1446113-23-0. Molecular formula: C23H16ClFN6OS. Mole weight: 478.93. | |
| Belvarafenib | Belvarafenib (HM95573) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC50s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv600E and C-RAF respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HM95573; GDC-5573; RG6185. CAS No. 1446113-23-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109080. | |
| Belzutifan | Belzutifan (PT2977) is an orally active and selective HIF-2α inhibitor with an IC50 of 9 nM. Belzutifan, as a second-generation HIF-2α inhibitor, increases potency and improves pharmacokinetic profile. Belzutifan is a potential treatment for clear cell renal cell carcinoma (ccRCC)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PT2977; MK-6482. CAS No. 1672668-24-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125840. | |
| Belzutifan Impurity 1 | Belzutifan Impurity 1. Uses: For analytical and research use. Alternative Names: 3-(((1S,2S,3S)-2,3-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile. CAS No. 1672668-51-7. Molecular formula: C17H12F3NO4S. Mole weight: 383.34. Catalog: APB1672668517. | |
| Belzutifan Impurity 2 | Belzutifan Impurity 2. Uses: For analytical and research use. Alternative Names: 3-(((1R,2R,3S)-2,3-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile. CAS No. 2007088-15-3. Molecular formula: C17H12F3NO4S. Mole weight: 383.34. Catalog: APB2007088153. | |
| Belzutifan Impurity 3 | Belzutifan Impurity 3. Uses: For analytical and research use. Alternative Names: 3-(((1R,2S,3R)-2,3-difluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile. CAS No. 3004833-91-1. Molecular formula: C17H12F3NO4S. Mole weight: 383.34. Catalog: APB3004833911. | |
| Belzutifan Impurity 4 | Belzutifan Impurity 4. Uses: For analytical and research use. Alternative Names: 3-fluoro-5-(((1S,2R,3R)-2-fluoro-1,3-dihydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)benzonitrile. CAS No. 1672668-57-3. Molecular formula: C17H13F2NO5S. Mole weight: 381.35. Catalog: APB1672668573. | |
| Belzutifan Impurity 5 | Belzutifan Impurity 5. Uses: For analytical and research use. Alternative Names: 3-(((1S,2S,3R)-3-(((1S,2R,3R)-4-(3-cyano-5-fluorophenoxy)-2-fluoro-3-(2-methoxyethoxy)-7-(methylsulfonyl)-2,3-dihydro-1H-inden-1-yl)oxy)-2-fluoro-1-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile. CAS No. 2738682-47-6. Molecular formula: C37H30F4N2O10S2. Mole weight: 802.77. Catalog: APB2738682476. | |
| Belzutifan Impurity 6 | Belzutifan Impurity 6. Uses: For analytical and research use. Alternative Names: 3-(((1S,2S,3S)-1-(((1R,2S,3S)-7-(3-cyano-5-fluorophenoxy)-2-fluoro-3-hydroxy-4-(methylsulfonyl)-2,3-dihydro-1H-inden-1-yl)oxy)-2-fluoro-3-hydroxy-7-(methylsulfonyl)-2,3-dihydro-1H-inden-4-yl)oxy)-5-fluorobenzonitrile. Molecular formula: C34H24F4N2O9S2. Mole weight: 744.69. Catalog: APB03721. | |
| Bemarituzumab | Bemarituzumab is a humanized IgG1 monoclonal antibody against FGFR2b (a FGF receptor). Bemarituzumab blocks fibroblast growth factors from binding and activating FGFR2b. Bemarituzumab has antitumor activity against gastric and breast cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1952272-74-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99010. | |
| Bemcentinib | Bemcentinib is a selective small molecule inhibitor of Axl kinase, which showed activity to blocks tumor spread and prolongs survival in models of metastatic breast cancer. The receptor tyrosine kinase Axl may play an important role in cancer progression, invasion, metastasis, drug resistance, and patient mortality. R428 inhibits Axl with low nanomolar activity and blocked Axl-dependent events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production. Pharmacologic investigations revealed favorable exposure after oral administration such that R428-treated tumors displayed a dose-dependent reduction in expression of the cytokine granulocyte macrophage colony-stimulating factor and the epithelial-mesenchymal transition transcriptional regulator Snail. In support of an earlier study, R428 inhibited angiogenesis in corneal micropocket and tumor models. R428 administration reduced metastatic burden and extended survival in MDA-MB-231 intracardiac and 4T1 orthotopic (median survival, >80 days compared with 52 days; P < 0.05) mouse models of breast cancer metastasis. Additionally, R428 synergized with cisplatin to enhance suppression of liver micrometastasis. Our results show that Axl signaling regulates breast cancer metastasis at multiple levels in tumor cells and tumor stromal cells and that selective Axl blockade confers therapeutic value in prolonging survival of animals bearing metastÂ… | |
| Bemcentinib | Bemcentinib (R428) is a selective and orally active Axl inhibitor with an IC50 of 14 nM. Bemcentinib retards cancer cell migration and invasion. Bemcentinib exhibits >100-fold selectivity for Axl versus Abl and 50- and >100-fold selectivity over TAM family kinases Mer and Tyro3, respectively, in cells. Bemcentinib blocks tumor spread and prolongs survival in models of metastatic breast cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R428; BGB324. CAS No. 1037624-75-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15150. | |
| Bemcentinib | Bemcentinib Inhibitor. Uses: Scientific use. Product Category: T6269. CAS No. 1037624-75-1. |  |
| Bemcentinib (R428) | Bemcentinib (R428, BGB324) is an inhibitor of Axl with IC50 of 14 nM, >100-fold selective for Axl versus Abl. Selectivty for Axl is also greater than Mer and Tyro3 (50-to-100- fold more selective) and InsR, EGFR, HER2, and PDGFRβ (100- fold more selective). Group: Inhibitors. Alternative Names: BGB324. CAS No. 1037624-75-1. Pack Sizes: 1mg. Product ID: S2841. Formula: C30H34N8. Smiles: C1CCN(C1)C2CCC3=C(CC2)C=C(C=C3)NC4=NN(C(=N4)N)C5=NN=C6C(=C5)CCCC7=CC=CC=C76. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| Bemnifosbuvir | Bemnifosbuvir (AT-511) is a potent and orally active HCV viral replication inhibitor. Bemnifosbuvir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC90=0.47 μM). Bemnifosbuvir has pangenotypic antiviral activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AT-511. CAS No. 1998705-64-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137958A. | |
| Bemnifosbuvir | Bemnifosbuvir is the precursor drug form of the antiviral nucleoside analogue AT-9010. It reduces the infectious virus yield in cells infected with Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome CoV (SARS-CoV), SARS-CoV-2, human CoV 229E (HCoV-229E), and HCoV-OC43 (EC90s = 37, 0.47, 2.8, 1.2, and 0.5 μM, respectively). Alternative Names: propan-2-yl N-[(P5'S,2'R)-2-amino-2'-deoxy-2'-fluoro-N6,2'-dimethyl-OP-phenyl-5'-adenylyl]-L-alaninate; AT-511; N-[[P(S),2'R]-2-amino-2'-deoxy-2'-fluoro-N,2'-dimethyl-P-phenyl-5'-adenylyl]-L-alanine, 1-methylethyl ester. Grades: 98%. CAS No. 1998705-64-8. Molecular formula: C24H33FN7O7P. Mole weight: 581.53. | |
| Bemnifosbuvir hemisulfate | Bemnifosbuvir is the precursor drug form of the antiviral nucleoside analogue AT-9010. It reduces the infectious virus yield in cells infected with Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome CoV (SARS-CoV), SARS-CoV-2, human CoV 229E (HCoV-229E), and HCoV-OC43 (EC90s = 37, 0.47, 2.8, 1.2, and 0.5 μM, respectively). Alternative Names: RG-6422; RO 7496998; AT-527; AT 527; AT527. Grades: 99.33%. CAS No. 2241337-84-6. Molecular formula: C24H33FN7O7P.1/2H2O4S. Mole weight: 679.61. | |
| Bemnifosbuvir hemisulfate | Bemnifosbuvir hemisulfate (AT-527), a hemisulfate salt of AT-511, a guanosine nucleotide proagent, is a potent and orally active HCV viral replication inhibitor. Bemnifosbuvir hemisulfate is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro (EC90=0.47 μM). Bemnifosbuvir hemisulfate has pangenotypic antiviral activity[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AT-527. CAS No. 2241337-84-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137958. | |
| Bemotrizinol | Bemotrizinol. Alternative Names: Bis-ethylhexyloxyphenol Methoxyphenyl Triazine; Phenol, 2,2-6-(4-methoxyphenyl)-1,3,5-triazine-2,4-diylbis5-(2-ethylhexyl)oxy-; Bisethylhexyloxyphenol Methoxyphenyl Triazine. Grades: 95%. CAS No. 187393-00-6. Molecular formula: C38H49N3O5. Mole weight: 627.83. | |
| Bemotrizinol | Bemotrizinol. Group: Biochemicals. Alternative Names: CGF 1607; FAT 70'884; Tinosorb S; Tinosorb S Aqua; BEMT; 2,4-Bis[4-(2-ethylhexyloxy)-2-hydroxyphenyl]-6-(4-methoxyphenyl)-1,3,5-triazine; 2,2'-[6-(4-Methoxyphenyl)-1,3,5-triazine-2,4-diyl]bis[5-[(2-ethylhexyl)oxy]phenol. Grades: Highly Purified. CAS No. 187393-00-6. Pack Sizes: 25mg. Molecular Formula: C38H49N3O5, Molecular Weight: 627.809999999999. US Biological Life Sciences. |  Worldwide |
| Bempedoic acid | Bempedoic acid is a synthetic small-molecule drug that acts as an inhibitor of ATP-citrate lyase (ACL), an enzyme in the hepatic cholesterol biosynthesis pathway upstream of HMG-CoA reductase (the target of statins). It is a prodrug activated by very long-chain acyl-CoA synthetase 1 (ACSVL1) in the liver, which converts it to the active-CoA thioester, ensuring liver-specific target engagement with minimal extrahepatic effects. Applications: Bempedoic acid is indicated as an adjunct to diet and maximally tolerated statin therapy for the treatment of heterozygous familial hypercholesterolemia or established atherosclerotic cardiovascular disease in adults who require additional ldl-cholesterol lowering. Category: Intermediates. CAS No. 738606-46-7. Product ID: INT738606467. Molecular formula: C19H36O5. Mole weight: 344.49. InChIKey: HYHMLYSLQUKXKP-UHFFFAOYSA-N. Appearance: White to off-white powder. |  |
| Bempedoic acid | Bempedoic acid (ETC-1002) is an ATP-citrate lyase (ACL) inhibitor[1]. Bempedoic acid (ETC-1002) activates AMPK[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ETC-1002; ESP-55016. CAS No. 738606-46-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-12357. | |
| Bempedoic Acid Impurity 1 | Bempedoic Acid Impurity 1. Uses: For analytical and research use. Alternative Names: 2,2,14,14-tetramethyl-8-oxopentadecanedioic acid. CAS No. 413624-71-2. Molecular formula: C19H34O5. Mole weight: 342.47. Catalog: APB413624712. | |
| Bempedoic Acid Impurity 10 | Bempedoic Acid Impurity 10. Uses: For analytical and research use. CAS No. 1529323-27-0. Molecular formula: C9H18O3. Mole weight: 174.24. Catalog: APB1529323270. | |
| Bempedoic Acid Impurity 10 | Bempedoic Acid Impurity 10. Uses: For analytical and research use. Alternative Names: 3-cyano-8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid. Molecular formula: C20H35NO5. Mole weight: 369.50. Catalog: APB03724. | |
| Bempedoic Acid Impurity 11 | Bempedoic Acid Impurity 11. Uses: For analytical and research use. CAS No. 36635-56-0. Molecular formula: C9H11NO3S. Mole weight: 213.25. Catalog: APB36635560. | |
| Bempedoic Acid Impurity 11 | Bempedoic Acid Impurity 11. Uses: For analytical and research use. Alternative Names: ethyl 7-bromo-2,2-dimethylheptanoate. CAS No. 123469-92-1. Molecular formula: C11H21BrO2. Mole weight: 265.19. Catalog: APB123469921. | |
| Bempedoic Acid Impurity 12 | Bempedoic Acid Impurity 12. Uses: For analytical and research use. Alternative Names: 7-bromo-2,2-dimethylheptanoic acid. CAS No. 7443-29-0. Molecular formula: C9H17BrO2. Mole weight: 237.13. Catalog: APB7443290. | |
| Bempedoic Acid Impurity 13 | Bempedoic Acid Impurity 13. Uses: For analytical and research use. Alternative Names: diethyl 8-isocyano-2,2,14,14-tetramethyl-8-tosylpentadecanedioate. CAS No. 738606-44-5. Molecular formula: C31H49NO6S. Mole weight: 563.79. Catalog: APB738606445. | |
| Bempedoic Acid Impurity 14 | Bempedoic Acid Impurity 14. Uses: For analytical and research use. Alternative Names: dimethyl 8-hydroxy-2,2,14,14-tetramethylpentadecanedioate. CAS No. 2511500-14-2. Molecular formula: C21H40O5. Mole weight: 372.54. Catalog: APB2511500142. | |
| Bempedoic Acid Impurity 15 | Bempedoic Acid Impurity 15. Uses: For analytical and research use. Alternative Names: 8-acetoxy-2,2,14,14-tetramethylpentadecanedioic acid. Molecular formula: C21H38O6. Mole weight: 386.52. Catalog: APB03723. | |
| Bempedoic Acid Impurity 16 | Bempedoic Acid Impurity 16. Uses: For analytical and research use. Alternative Names: 8-hydroxy-15-methoxy-2,2,14,14-tetramethyl-15-oxopentadecanoic acid. Molecular formula: C20H38O5. Mole weight: 358.51. Catalog: APB03722. | |
| Bempedoic Acid Impurity 2 | Bempedoic Acid Impurity 2. Uses: For analytical and research use. Alternative Names: 8,14-dihydroxy-2,2,20,20-tetramethylhenicosanedioic acid. CAS No. 2570179-40-5. Molecular formula: C25H48O6. Mole weight: 444.65. Catalog: APB2570179405. | |
| Bempedoic Acid Impurity 3 | Bempedoic Acid Impurity 3. Uses: For analytical and research use. Alternative Names: 3,3-diethyl-2,2,14,14-tetramethyl-8-oxopentadecanedioic acid. Molecular formula: C23H42O5. Mole weight: 398.58. Catalog: APB03728. | |
| Bempedoic Acid Impurity 4 | Bempedoic Acid Impurity 4. Uses: For analytical and research use. Alternative Names: 7-(5-carboxy-5-methylhexyl)-8-hydroxy-2,2,14,14-tetramethylpentadecanedioic acid. Molecular formula: C27H50O7. Mole weight: 486.68. Catalog: APB03727. | |
| Bempedoic Acid Impurity 5 | Bempedoic Acid Impurity 5. Uses: For analytical and research use. Alternative Names: 2,2,8,8-tetramethylnonanedioic acid. CAS No. 30313-67-8. Molecular formula: C13H24O4. Mole weight: 244.33. Catalog: APB30313678. | |
| Bempedoic Acid Impurity 6 | Bempedoic Acid Impurity 6. Uses: For analytical and research use. CAS No. 59415-00-8. Molecular formula: C11H22O2. Mole weight: 186.3. Catalog: APB59415008. | |
| Bempedoic Acid Impurity 6 | Bempedoic Acid Impurity 6. Uses: For analytical and research use. Alternative Names: diethyl 2,2,14,14-tetramethyl-8-oxopentadecanedioate. CAS No. 738606-43-4. Molecular formula: C23H42O5. Mole weight: 398.58. Catalog: APB738606434. | |
| Bempedoic Acid Impurity 7 | Bempedoic Acid Impurity 7. Uses: For analytical and research use. Alternative Names: diethyl 8-hydroxy-2,2,14,14-tetramethylpentadecanedioate. CAS No. 738606-64-9. Molecular formula: C23H44O5. Mole weight: 400.59. Catalog: APB738606649. | |
| Bempedoic Acid Impurity 8 | Bempedoic Acid Impurity 8. Uses: For analytical and research use. Alternative Names: 15-ethoxy-8-hydroxy-2,2,14,14-tetramethyl-15-oxopentadecanoic acid. Molecular formula: C21H40O5. Mole weight: 372.54. Catalog: APB03726. | |
| Bempedoic Acid Impurity 9 | Bempedoic Acid Impurity 9. Uses: For analytical and research use. Alternative Names: 15-ethoxy-2,2,14,14-tetramethyl-8,15-dioxopentadecanoic acid. Molecular formula: C21H38O5. Mole weight: 370.52. Catalog: APB03725. | |
| Bempikibart | Bempikibart (ADX-914) is a fully human anti-IL-7Rα antibody that re-regulates adaptive immune function by blocking signaling mediated by both IL-7 and thymic stromal lymphopoietin (TSLP). Bempikibart can be used for the study of atopic dermatitis and alopecia areata[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ADX-914. CAS No. 2622254-57-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990023. | |
| Benadrostin | Benadrostin is produced by the strain of Streptomyces flavovirens MH499-O'Flc. Poly-(adp-Ribose) synthetase was inhibited with IC50 of 35μmol/L. Alternative Names: 8-Hydroxy-2H-1,3-benzoxazine-2,4(3H)-dione; 2H-1,3-Benzoxazine-2,4(3H)-dione, 8-hydroxy-. CAS No. 117241-60-8. Molecular formula: C8H5NO4. Mole weight: 179.13. | |
| Benafentrine | Benafentrine. Group: Biochemicals. Alternative Names: rel-N-[4-[(4aR, 10bS)-1, 2, 3, 4, 4a, 10b-hexahydro-8, 9-dimethoxy-2-methylbenzo[c][1, 6]naphthyridin-6-yl]phenyl]acetamide. Grades: Highly Purified. CAS No. 35135-01-4. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C23H27N3O3. US Biological Life Sciences. | Worldwide |
| Benalaxyl | Benalaxyl. Group: Biochemicals. Alternative Names: N-(2,6-Dimethylphenyl)-N-(phenylacetyl)alanine methyl ester; N-(2,6-Dimethylphenyl)-N-(phenylacetyl)-DL-alanine methyl ester. Grades: Highly Purified. CAS No. 71626-11-4. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C20H23NO3. US Biological Life Sciences. | Worldwide |
| Benanomicin A | Benanomicin A is produced by the strain of Actinomadura sp. MH193-16F4. A and B have anti-candida, Cryptococcus neoforme, Saccharomyces cerevisiae and other fungal activities, while A has stronger activity. Xylose benamycin A and B showed similar or slightly stronger activity against candida, yeast and Cryptococcus, but decreased activity against aspergillus. The antifungal activity of 2-demethylbenamycin was similar to that of xylose Benamycin A. The synthesized 7-methoxybenamycin had little antifungal activity, but showed inhibitory activity of glucosinolase (EC 3.2.1.20) with IC50 of 60μg/mL. Alternative Names: Benanomicin A;116249-65-1;(2R)-2-[[(5S,6S)-5-[(2S,3R,4S,5S,6R)-3,5-dihydroxy-6-methyl-4-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-1,6,9,14-tetrahydroxy-11-methoxy-3-methyl-8,13-dioxo-5,6-dihydrobenzo[a]tetracene-2-carbonyl]amino]propanoic acid;D-Alanine, N-((5-((6-deoxy-3-O-beta-D-xylopyranosyl-beta-D-galactopyranosyl)oxy)-5,6,8,13-tetrahydro-1,6,9,14-tetrahydroxy-11-methoxy-3-meth. CAS No. 116249-65-1. Molecular formula: C39H41NO19. Mole weight: 827.74.Â… | |
| Benanomicin B | Benanomicin B is produced by the strain of Actinomadura sp. MH193-16F4. A and B have anti-candida, Cryptococcus neoforme, Saccharomyces cerevisiae and other fungal activities, while A has stronger activity. Xylose benamycin A and B showed similar or slightly stronger activity against candida, yeast and Cryptococcus, but decreased activity against aspergillus. The antifungal activity of 2-demethylbenamycin was similar to that of xylose Benamycin A. The synthesized 7-methoxybenamycin had little antifungal activity, but showed inhibitory activity of glucosinolase (EC 3.2.1.20) with IC50 of 60μg/mL. Alternative Names: Pradimicin C; D-Alanine, N-((5-((4-amino-4,6-dideoxy-3-O-beta-D-xylopyranosyl-beta-D-galactopyranosyl)oxy)-5,6,8,13-tetrahydro-1,6,9,14-tetrahydroxy-11-methoxy-3-methyl-8,13-dioxobenzo(a)naphthacen-2-yl)carbonyl)-. CAS No. 116249-66-2. Molecular formula: C39H42N2O18. Mole weight: 826.75. | |
| Benarthin | Benarthin is produced by the strain of Streptomyces xanthophaeus MJ 244-SF1. It inhibited the activity of pyroglutaminase and competed with the substrate, and the inhibitory constant Ki and Km was 1.2x10-6 mol/L and 3.3x10-5 mol/L, respectively. Alternative Names: N-(N(sup 2)-(2,3-Dihydroxybenzoyl)-L-arginyl)-L-threonine; L-Threonine, N-(N2-(2,3-dihydroxybenzoyl)-L-arginyl)-. CAS No. 143651-45-0. Molecular formula: C17H25N5O7. Mole weight: 411.41. | |
| Benarthin | Benarthin is an orally active Pyroglutamyl peptidase inhibitor, THY1 inhibitor (with a Kd value of 5.13e-08 M) and competitive PGP-1 inhibitor (Ki = 1.2 μM). Benarthin is isolated from the culture broth of Streptomyces xanthophaeus MJ244-SF1. Benarthin disrupts the THY1-SFRP1 interaction, inhibits the activation of the GSK3α/β-β-catenin pathway, and reduces the upregulation of FASLG. Benarthin attenuates urothelial anoikis and reduces cell Apoptosis. Benarthin possesses iron-chelating activity. Benarthin maintains urothelial barrier integrity and blocks the pathological cascade of renal interstitial fibroblasts induced by HAP stimulation. Benarthin can be used in studies related to kidney stones[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 143651-45-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-117738. | |
| Benastatin A | Benastatin A is produced by the strain of Streptomyces sp. MI 384-DF12. It can inhibit glutathione transferase (GST) activity. Alternative Names: Benzo(a)naphthacene-2-carboxylic acid, 8,13-dihydro-13,13-dimethyl-8-oxo-3-pentyl-1,7,9,11-tetrahydroxy-. CAS No. 138968-85-1. Molecular formula: C30H28O7. Mole weight: 500.54. | |
| Benastatin B | Benastatin B is produced by the strain of Streptomyces sp. MI 384-DF12. It can inhibit glutathione transferase (GST) activity. Alternative Names: Benzo(a)naphthacene-2-carboxylic acid, 5,6,8,13-tetrahydro-13,13-dimethyl-8-oxo-3-pentyl-1,7,9,11-tetrahydroxy-. CAS No. 138968-86-2. Molecular formula: C30H30O7. Mole weight: 502.55. | |
| Benastatin C | Benastatin C is produced by the strain of Streptomyces sp. MI 384-DF12. It can inhibit glutathione transferase (GST) activity. Alternative Names: 13,13-Dimethyl-3-pentyl-1,7,9,11-tetrahydroxybenzo(a)naphthacen-8(13H)-one; Benzo(a)naphthacen-8(13H)-one, 1,7,9,11-tetrahydroxy-13,13-dimethyl-3-pentyl-. CAS No. 150151-88-5. Molecular formula: C29H28O5. Mole weight: 456.53. | |
| Benazeprilat | A metabolite of Benazepril, which is used as an antihypertensive. Group: Biochemicals. Grades: Highly Purified. CAS No. 86541-78-8. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Benazeprilat | Benazeprilat is the active metabolite of benazepril, formed after cleavage of the ester group. It is a potent inhibitor of angiotensin-converting enzyme (ACE). Alternative Names: Benazepril Related Compound C; Benazepril USP Related Compound C; Benazepril Diacid; (3S)-3-[[(1S)-1-Carboxy-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic Acid. Grades: 95%. CAS No. 86541-78-8. Molecular formula: C22H24N2O5. Mole weight: 396.45. | |
| Benazeprilat-d5 | A labeled metabolite of Benazepril, which is used as an antihypertensive. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Benazeprilat Ethyl tert-Butyl Diester | Benazeprilat Ethyl tert-Butyl Diester is an analog of Benazepril (B119750). Group: Biochemicals. Alternative Names: (3S) -3-[[ (1S) -1-[ (1, 1-Dimethylethoxy) carbonyl]-3-phenylpropyl]amino]-2, 3, 4, 5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 859635-53-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Benazepril-d5 | Labelled Benazepril, which is used as an antihypertensive. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Benazepril-[d5] | Benazepril-[d5] is a labelled compound of Benazepril. Benazepril is a drug of the angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure. Alternative Names: (3S)-3-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic Acid; Lotensin. CAS No. 1279200-03-1. Molecular formula: C24H23D5N2O5. Mole weight: 429.52. | |
| Benazepril-d5 Acyl-b-D-glucuronide | Labelled Benazepril-glucuronide, which is used as an antihypertensive. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Benazepril-d5 Hydrochloride | Benazepril-d5 Hydrochloride is the labeled analogue of Benazepril Hydrochloride (B119750), which is used as an antihypertensive; angiotensin converting enzyme inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1279026-26-4. Pack Sizes: 1mg. Molecular Formula: C24H24D5ClN2O5. US Biological Life Sciences. | Worldwide |
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