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| Product | Description | |
|---|---|---|
| BC11-38 | BC11-38 is a potent, selective, and biologically active PDE11 inhibitor, with IC50s of 0.28 μM and >100 μM for PDE11 and PDE1-10, respectively. BC11-38 elevates cAMP levels, PKA-mediated ATF-1 phosphorylation, and cortisol production in H295R cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 686770-80-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108618. |  |
| BC 11 hydrobromide | BC 11 hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 443776-49-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| BC-11 hydrobromide | BC 11 hydrobromide is a selective urokinase (uPA) inhibitor (IC50 = 8.2 μM) with no activity at 8 other related enzymes. BC 11 inhibits clot lysis displaying no effect on clot formation. It also decreases viability of MDA-MB231 breast cancer cells in vitro. Synonyms: BC 11 hydrobromide; 443776-49-6; BC-11 hydrobromide; BC11 hydrobromide; (4-((Carbamimidoylthio)methyl)phenyl)boronic acid hydrobromide; BC-11 (hydrobromide); uPA inhibitor BC-11 hydrobromide; GLXC-15931; AKOS024458122; DA-61527; HY-108447; CS-0028707; G82409; 4-(Carbamimidoylthiomethyl)phenylboronic acid hydrobromide; [4-(carbamimidoylsulfanylmethyl)phenyl]boronic acid; hydrobromide; {4-[(Carbamimidoylsulfanyl)methyl]phenyl}boronic acid hydrobromide. CAS No. 443776-49-6. Molecular formula: C8H12BBrN2O2S. Mole weight: 290.97. |  |
| BC-11 hydrobromide | BC-11 hydrobromide is a selective TMPRSS2 inhibitor (TMPRSS2 is a key host cellular factor for viral entry and SARS-CoV-2 pathogenesis), and a selective urokinase (uPA) inhibitor (IC50=8.2 μM). BC-11 hydrobromide is cytotoxic to triple-negative MDA-MB231 breast cancer cells. BC-11 hydrobromide is used in research on viral infections and cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 443776-49-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-108447. | |
| BC-1215 | BC-1215 is an inhibitor of F-box protein 3 (FBXO3) with an IC50 of 0.9 μg/mL for IL-1β release. It acts by antagonizing Fbxo3 in TRAF cell signaling and displays a low IC50 in vitro. BC-1215 can be used for inflammation research. Synonyms: N1,N2-bis[[4-(2-pyridinyl)phenyl]methyl]-1,2-ethanediamine. Grade: ≥98%. CAS No. 1507370-20-8. Molecular formula: C26H26N4. Mole weight: 394.51. | |
| BC-1258 | BC-1258 is an F-box/LRR-repeat protein 2 (FBXL2) activator. BC-1258 stabilized and increased levels of FBXL2 protein that promoted Aurora B degradation, resulting in tetraploidy, mitotic arrest and apoptosis of tumorigenic cells, and profoundly inhibiting tumor formation in athymic nude mice. Synonyms: BC 1258; BC1258; N1,N2-Bis(4-(thiazol-2-yl)benzyl)ethane-1,2-diamine. Grade: >98%. CAS No. 1507370-40-2. Molecular formula: C22H22N4S2. Mole weight: 406.57. | |
| BC-1293 | BC-1293 is an inhibitor for E3 ligase subunit FBXO24. BC-1293 disrupts the interaction between FBXO24 and aspartyl-tRNA synthetase (DARS2) and increases the level of DARS2. BC-1293 increases levels of IL-1β, IL-9, MIP-2, and TNF α, and exhibits immunostimulatory activity in mice[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1219395-86-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-161901. | |
| BC-1382 | BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction (IC50? 5 nM).Anti-inflammatory activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1013753-99-5. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W062696. | |
| BC-1471 | BC-1471 is a STAMBP deubiquitinase inhibitor with an IC50 of 0.33 μM. BC-1471 can inhibit the activity of the NALP7 inflammasome. BC-1471 has anti-inflammatory activity and can be used for the research of inflammatory diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 896683-84-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-122883. | |
| BC1618 | BC1618 is an orally active inhibitor of F-box only protein 48 (FBXO48) that stimulates Ampk-dependent signaling. BC1618 promotes mitochondrial fission, facilitates autophagy and improves hepatic insulin sensitivity in high-fat-diet-induced obese mice. Synonyms: BC-1618; BC 1618. CAS No. 2222094-18-8. Molecular formula: C24H24F3NO2. Mole weight: 415.45. | |
| BC1618 | BC1618, an orally active Fbxo48 inhibitory compound, stimulates Ampk-dependent signaling (via preventing activated pAmpkα from Fbxo48-mediated degradation). BC1618 promotes mitochondrial fission, facilitates autophagy and improves hepatic insulin sensitivity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2222094-18-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134656. | |
| BC2059 | BC2059 is a novel β-catenin antagonist and its treatment dose-dependently induced apoptosis of cultured and primary AML BPCs. BC2059 also significantly improved the median survival of immune-depleted mice engrafted with either cultured or primary AML BPCs, showing nuclear expression of β-catenin. Synonyms: BC2059; BC-2059; BC 2059; (9E,10E)-2,7-bis(((3R,5S)-3,5-dimethylpiperidin-1-yl)sulfonyl)anthracene-9,10-dione dioxime. Grade: 98%. CAS No. 1227637-23-1. Molecular formula: C28H36N4O6S2. Mole weight: 588.74. | |
| BCA | BCA (Disodium bicinchoninate) is an orally active and non-competitive Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 value of 28 μM, a Ki value of 43 μM. BCA shows anticancer activity. BCA has the potential for the research of Alzheimer's disease (AD)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Disodium bicinchoninate. CAS No. 979-88-4. Pack Sizes: 10 mM * 1 mL in Water; 5 g; 10 g; 25 g; 50 g; 100 g; 500 g; 1 k g. Product ID: HY-15908. | |
| BCAA | It is a monocarboxylic acid, an organochlorine compound and a 2-bromocarboxylic acid. Category: Amino acids and derivatives. Synonyms: Bromochloroacetic acid. 5589-96-8. 2-bromo-2-chloroacetic acid. Acetic acid, bromochloro-. Keratins. CAS No. 69430-36-0. Product ID: API69430360. Molecular formula: C2H2BrClO2. Mole weight: 173.39. EINECS: 627-754-9. SMILES: C(C(=O)O)(Cl)Br. Appearance: Crystalline compound. Standard: In-house. |  |
| BCAA Powder (2:1:1) | BCAA Powder (2:1:1). |  CA, FL & NJ |
| b-Carotene 5,6-epoxide | b-Carotene 5,6-epoxide. Group: Biochemicals. Alternative Names: (5RS,6RS)-5,6-Epoxy-5,6-dihydro-b,b-carotene. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| b-Caryophyllene oxide | b-Caryophyllene oxide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1139-30-6. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C15H24O. US Biological Life Sciences. | Worldwide |
| b-Casomorphin (1-3) acetate | b-Casomorphin (1-3) acetate is a tripeptide with opioid effects. Synonyms: H-Tyr-Pro-Phe-OH.CH3CO2H; YPF acetate; L-tyrosyl-L-prolyl-L-phenylalanine acetic acid. Grade: ≥95%. CAS No. 2763583-71-5. Molecular formula: C23H27N3O5.C2H4O2. Mole weight: 485.53. | |
| BCAT | BCAT. Synonyms: Benzotriazole-1-Carboxamidinium Tosylate; 1H-Benzotriazole-1-carboximidamide, 4-methylbenzenesulfonate (1:1). Grade: 95%. CAS No. 163853-10-9. Molecular formula: C7H8N5.C7H7O3S. Mole weight: 333.37. | |
| BCATc Inhibitor 2 | BCATc Inhibitor 2 is a selective branched-chain aminotransferase (BCAT) inhibitor for research of neurodegenerative diseases. The IC50s of 0.2 μM, 0.8 μM and 3.0 μM for rat cytosolic isoenzyme rBCATc, human cytosolic isoenzyme hBCATc and rat mitochondrial isoenzyme rBCATm, respectively. BCATc, also called BCAT1, is in the cytoplasm[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 406191-34-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116044. | |
| BCATc Inhibitor 2 | BCATc Inhibitor 2 is a sulfonyl hydrazide that inhibits BCATc with IC50s of 0.81 for human and IC50 s of 0.2 μM for rat. It is 15-fold selectivity over BCATm. It has also been used to block calcium influx into neurons with IC50 of 4.8 μM following inhibition of glutamate uptake and to demonstrate neuroprotective efficacy in an in vivo rat model of neurodegeneration. Synonyms: Cytosolic Branched-Chain Amino Acid Transferase Inhibitor 2. Grade: ≥98%. CAS No. 406191-34-2. Molecular formula: C16H10ClF3N2O4S. Mole weight: 418.8. | |
| BCAT-IN-1 | BCAT-IN-1 is a potent, selective and orally active inhibitor of BCATm, with a pIC50 of 7.3. BCAT-IN-1 shows 100-fold selectivity for BCATm over BCATc (pIC50=5.4). BCAT-IN-1 can be used for the research of metabolic diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1875078-61-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141668. | |
| BCAT-IN-2 | BCAT-IN-2 is a potent, selective and orally active inhibitor of mitochondrial branched-chain aminotransferase (BCATm), with a pIC50 of 7.3. BCAT-IN-2 shows selectivity for BCATm over BCATc (pIC50=6.6). BCAT-IN-2 can be used for the research of obesity and dislipidema[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1800024-45-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141669. | |
| bcbp | bcbp. CAS No. 858131-70-1. Molecular formula: C48H32N2. Mole weight: 636.8g/mol. IUPAC Name: 9-[4-[2-[2-(4-carbazol-9-ylphenyl)phenyl]phenyl]phenyl]carbazole. SMILES: C1=CC=C(C(=C1)C2=CC=C(C=C2)N3C4=CC=CC=C4C5=CC=CC=C53)C6=CC=CC=C6C7=CC=C(C=C7)N8C9=CC=CC=C9C1=CC=CC=C18. InChI: InChI=1S/C48H32N2/c1-3-15-39(37(13-1)33-25-29-35(30-26-33)49-45-21-9-5-17-41(45)42-18-6-10-22-46(42)49)40-16-4-2-14-38(40)34-27-31-36(32-28-34)50-47-23-11-7-19-43(47)44-20-8-12-24-48(44)50/h1-32H. |  |
| BCECF-AM | BCECF-AM. Group: Biochemicals. Grades: Purified. CAS No. 117464-70-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| b-Cellobiosyl azide | b-Cellobiosyl azide is a highly versatile biomedical compound, acting as a precursor for synthesizing glycoconjugates and glycosylated natural drugs. Leveraging its profound influence on protein function and stability, this remarkable compound has become extensively utilized in cutting-edge drug development and advanced pharmaceutical investigations. Synonyms: 4-O-b-D-Glucopyranosyl-b-D-glucopyranosyl azide. CAS No. 69194-62-3. Molecular formula: C12H21N3O10. Mole weight: 367.3. | |
| BCG Vaccine | BCG Vaccine is a vaccine primarily used against tuberculosis (TB). BCG also has some effectiveness against Buruli ulcer infection and other nontuberculous mycobacterial infections. Additionally, it is sometimes used as part of the treatment of bladder cancer. Synonyms: Bacillus Calmette. | |
| BCH | BCH (2-Amino-2-norbornanecarboxylic acid) is a selective and competitive inhibitor of large neutral amino acid transporter 1 (LAT1) significantly inhibit cellular uptake of amino acids and mTOR phosphorylation, which induces the suppression of cancer growth and apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Amino-2-norbornanecarboxylic acid; LAT1-IN-1. CAS No. 20448-79-7. Pack Sizes: 10 mM * 1 mL in Water; 50 mg; 100 mg. Product ID: HY-108540. | |
| BCH | BCH is an inhibitor of L-type amino acid transporter (LAT1), which is a therapeutic target for human esophageal squamous cell carcinoma. BCH inhibits growth and induces apoptosis via activation of caspases in KB, Saos2 and C6 cancer cell lines. Synonyms: 2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid. CAS No. 20448-79-7. Molecular formula: C8H13NO2. Mole weight: 155.2. | |
| BCH | BCH. Group: Biochemicals. Grades: Purified. CAS No. 20448-79-7. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| BCH001 | BCH001 is a specific PAPD5 inhibitor. BCH001 restores telomerase activity and telomere length in DC patient induced pluripotent stem cells. Synonyms: 2-((3-(Ethoxycarbonyl)-6-(trifluoromethoxy)quinolin-4-yl)amino)benzoicacid. CAS No. 384859-58-9. Molecular formula: C20H15F3N2O5. Mole weight: 420.34. | |
| BChE inhibitor 8012-9656 | BChE inhibitor 8012-9656 is a potent and selective inhibitor of butyrylcholinsterase (BChE). It inhibits BChE in a noncompetitive manner and could occupy the binding pocket forming diverse interactions with the target. Synonyms: 2-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1H-benzo[d]imidazol-1-yl)-N-(2-methylquinolin-6-yl)acetamide. Grade: 98%. CAS No. 446266-84-8. Molecular formula: C21H17N7O2. Mole weight: 399.41. | |
| b-Chloralose | b-Chloralose is a renowned compound employed for the research of sedation and anesthesia functioning as a central nervous system depressant. Uses: Anesthetics, intravenous. Synonyms: beta-Chloralose; (R)-1-((2S,3aR,5R,6S,6aR)-6-hydroxy-2-(trichloromethyl)tetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethane-1,2-diol. CAS No. 16376-36-6. Molecular formula: C8H11Cl3O6. Mole weight: 309.53. | |
| b-Chloro-D-alanine 99+% (TLC) | b-Chloro-D-alanine 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| b-Chloro-DL-alanine hydrochloride 98+% (TLC) | b-Chloro-DL-alanine hydrochloride 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
| b-Chloro-L-alanine ≥95% (HPLC) | b-Chloro-L-alanine ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| b-Chloro-L-alanine hydrochloride | b-Chloro-L-alanine hydrochloride. Synonyms: b-Chloro-L-Ala-OH HCl; (R)-2-Amino-3-chloropropionic acid hydrochloride; 3-Chloro-L-alanine Hydrochloride; beta-Chloro-L-alanine hydrochloride; L-Alanine, 3-chloro-, hydrochloride; 3-Chloro-l-alanine HCl; H-Ala(3-Cl)-OH HCl. Grade: ≥ 95% (HPLC). CAS No. 51887-89-9. Molecular formula: C3H6NO2Cl·HCl. Mole weight: 160.00. | |
| b-Chloro-L-alanine hydrochloride | b-Chloro-L-alanine hydrochloride. Group: Biochemicals. Alternative Names: b-Chloro-L-Ala-OH·HCl; (R)-2-Amino-3-chloropropionic acid hydrochloride. Grades: Highly Purified. CAS No. 51887-89-9. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C3H6NO2Cl·HCl. US Biological Life Sciences. | Worldwide |
| b-Chloro-L-alanine hydrochloride ≥95% (HPLC) | b-Chloro-L-alanine hydrochloride ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| b-Chloro-L-alanine methyl ester hydrochloride 98+% (TLC) | b-Chloro-L-alanine methyl ester hydrochloride 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| b-Cholestanol | b-Cholestanol. Group: Biochemicals. Alternative Names: 5a-Cholestan-3b-ol. Grades: Highly Purified. CAS No. 80-97-7. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C27H48O. US Biological Life Sciences. | Worldwide |
| BCI | BCI ((E)-BCI) is a DUSP6 (dual specificity phosphatase 6) inhibitor. BCI shows anti-inflammatory activity and decreases reactive oxygen species (ROS) production. BCI can be used in inflammatory disease research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (E)-BCI. CAS No. 1245792-51-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115502. | |
| BCI | BCI is an allosteric inhibitor of dual-specificity phosphatases (DUSP). BCI treatment of DUSP6-Myc-transfected cells suppresses DUSP6 or DUSP1 activity. BCI induces expansion of myocardial progenitors that ultimately increases heart size in zebrafish embryos via inhibiting DUSP6. BCI also inhibits lung cancer and uveal melanoma cells viability (IC50 = 0.1 to 90 μM). DUSP6 functions a feedback regulator of fibroblast growth factor (FGF) signaling to limit the activity of extracellular signal-regulated kinases (ERKs) 1 and 2. Synonyms: (E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one; (2E)-2-Benzylidene-3-(cyclohexylamino)-1-indanone. Grade: 99%. CAS No. 1245792-51-1. Molecular formula: C22H23NO. Mole weight: 317.42. | |
| BCI-121 | BCI-121, a SMYD3 inhibitor, induces a significant reduction in SMYD3 activity both in vitro and in CRC cells. Synonyms: 1-[2-(4-bromoanilino)-2-oxoethyl]piperidine-4-carboxamide; 1-(2-((4-bromophenyl)amino)-2-oxoethyl)piperidine-4-carboxamide; 1-{2-[(4-bromophenyl)amino]-2-oxoethyl}piperidine-4-carboxamide; BAS 04914128; AC1LGJJ6. CAS No. 432529-82-3. Molecular formula: C14H18BrN3O2. Mole weight: 340.22. | |
| BCI-137 | BCI-137 is a competitive Argonaute 2 (Ago2) ligand (IC50 = 342 μM) that acts by targeting the MicroRNA binding domain. Synonyms: Alanine, N-[(1,2,3,4-tetrahydro-2,3-dioxo-6-quinoxalinyl)sulfonyl]-; DL-Alanine, N-[(1,2,3,4-tetrahydro-2,3-dioxo-6-quinoxalinyl)sulfonyl]-; N-[(1,2,3,4-Tetrahydro-2,3-dioxo-6-quinoxalinyl)sulfonyl]alanine; 2-(2,3-Dioxo-1,2,3,4-tetrahydroquinoxaline-6-sulfonamido)propanoic acid; BCI 137; BCI137. Grade: 95%. CAS No. 112170-24-8. Molecular formula: C11H11N3O6S. Mole weight: 313.29. | |
| BCI-137 | BCI-137 is a Argonaute 2 (AGO2) inhibitor. By inhibiting AGO2 function, reducing PTPN6/SHP-1 protein levels and enhancing STAT1 phosphorylation, BCI-137 restores the sensitivity of tumor cells to IFN-γ. BCI-137 effectively enhances the recruitment, activation and cytotoxicity of CD8+ T cells. BCI-137 exerts a synergistic effect with anti-PD-1 antibodies and significantly reduces tumor volume in preclinical mouse models. BCI-137 exhibits favorable safety profiles and does not cause significant weight loss or death in mice. BCI-137 can be used in research related to bladder cancer, colorectal cancer, melanoma and other related fields[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 112170-24-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-119024. | |
| BCI-215 | BCI-215 is a potent and tumor cell-selective dual specificity MAPK phosphatase (DUSP-MKP) inhibitor. BCI-215 has cytotoxicity for tumor cells but not normal cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1245792-67-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121087. | |
| BCI hydrochloride | BCI ((E)-BCI) hydrochloride is a DUSP6 (dual specificity phosphatase 6) inhibitor. BCI hydrochloride shows anti-inflammatory activity and decreases reactive oxygen species (ROS) production. BCI hydrochloride can be used in inflammatory disease research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (E)-BCI hydrochloride. CAS No. 95130-23-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115502A. | |
| BCI hydrochloride | BCI hydrochloride is an allosteric inhibitor of Dusp6, acting within the phosphatase domain to prevent the catalytic stimulation of phosphatase activity induced by ERK2 substrate binding. BCI also inhibits lung cancer and uveal melanoma cells viability (IC50 values ranging from 0.1 to 90 μM). It prevents pERK2 dephosphorylation induced by Dusp6 in vitro. It is selective for Dusp6 and Dusp1 over Dusp3/VHR, Cdc25B, and PTP1B, for which it has no activity. Synonyms: 2-Benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one hydrochloride. Grade: ≥95%. CAS No. 95130-23-7. Molecular formula: C22H23NO·HCl. Mole weight: 353.9. | |
| BCIP | BCIP(BCIP p-toluidine salt; X-phosphate p-toluidine salt) is an artificial chromogenic substrate used for the sensitive colorimetric detection of alkaline phosphatase activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BCIP p-toluidine salt; X-phosphate p-toluidine salt. CAS No. 6578-6-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-15909. | |
| BCIP Na) 5-Bromo-4-chloro-3-indolyl phosphate disodium salt | 1g Pack Size. Group: Building Blocks, Stains & Indicators. Formula: C8H4BrClNO4Na2P. CAS No. 102185-33-1. Prepack ID 67003351-1g. Molecular Weight 370.43. See USA prepack pricing. |  |
| BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine salt | 1g Pack Size. Group: Analytical Reagents, Biochemicals, Diagnostic Raw Materials. Formula: C8H5BrClNO4P ·C7H10N. CAS No. 6578-6-9. Prepack ID 21540524-1g. Molecular Weight 433.62. See USA prepack pricing. | |
| Bcl-2 Antibody [D6K15] | Bcl2,Bcl-2. Group: Antibodies. Alternative Names: Apoptosis regulator Bcl-2. CAS No. Pack Sizes: 20uL. Product ID: F2515. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| Bcl-2 Antibody [H20N17] | Bcl2,Bcl-2. Group: Antibodies. Alternative Names: Bcl-2. Pack Sizes: 20uL. Product ID: F0125. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Bcl-2 Binding Peptide, cell permeable | It is a peptide that binds to Bcl-2 with high affinity. It is derived from the BH3 domain (a death domain) of Bad, amino acid residues 140 to 165, and is cellular permeable due to the N-terminal modification by a decanoyl moiety. Synonyms: Decanoyl-Lys-Asn-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Leu-Arg-Arg-Met-Ser-Asp-Glu-Phe-Glu-Gly-Ser-Phe-Lys-Gly-Leu-OH; N-decanoyl-L-lysyl-L-asparagyl-L-leucyl-L-tryptophyl-L-alanyl-L-alanyl-L-glutaminyl-L-arginyl-L-tyrosyl-glycyl-L-arginyl-L-alpha-glutamyl-L-leucyl-L-arginyl-L-arginyl-L-methionyl-L-seryl-L-alpha-aspartyl-L-alpha-glutamyl-L-phenylalanyl-L-alpha-glutamyl-glycyl-L-seryl-L-phenylalanyl-L-lysyl-glycyl-L-leucine. Grade: ≥95% by HPLC. Molecular formula: C153H240N44O42S. Mole weight: 3399.93. | |
| BCL2-IN-1 | BCL2-IN-1, a potent Bcl-2 inhibitor, binds Bcl-2 with a Ki of <0.01 nM. Synonyms: 4-(4-{[2-(4-Chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl}-1-piperazinyl)-N-[(4-{[(trans-4-methoxycyclohexyl)methyl]amino}-3-nitrophenyl)sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide; Benzamide, 4-[4-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(trans-4-methoxycyclohexyl)methyl]amino]-3-nitrophenyl]sulfonyl]-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)-. Grade: 98%. CAS No. 1257044-75-9. Molecular formula: C47H54ClN7O7S. Mole weight: 896.49. | |
| Bcl-2-IN-2 | Bcl-2-IN-2 is a potent and selective Bcl-2 inhibitor with an IC50 of 0.034 nM, and also inhibits Bcl-xL with an IC50 of 43 nM, showing >1000-fold selectivity for Bcl-2 over Bcl-xL. Synonyms: (S)-2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-(2-(2-(2-ethylphenyl)pyrrolidin-1-yl)-7-azaspiro[3.5]nonan-7-yl)-N-((4-(((4-hydroxy-4-methylcyclohexyl)methyl)amino)-3-nitrophenyl)sulfonyl)benzamide. Grade: ≥95%. CAS No. 2383085-86-5. Molecular formula: C48H57N7O7S. Mole weight: 876.07. | |
| Bcl-2-like protein 1 (173-182) | Bcl-2-like protein 1 (173-182) is a 10-aa peptide. Bcl-2-like protein 1 is a potent inhibitor of cell death. It inhibits activation of caspases. Synonyms: Bcl2-L-1 (173-182); Apoptosis regulator Bcl-X (173-182). | |
| BCL6-IN-13 | BCL6-IN-13 (compound I-94) inhibits BCL6 with an IC50 of 2 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2230407-20-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156595. | |
| BCL6-IN-4 | BCL6-IN-4 is a potent inhibitor of B-cell lymphoma 6 (BCL6) with an IC50 of 97 nM. BCL6-IN-4 has antitumor activity. Synonyms: 2H-Benzimidazol-2-one, 5-[[5-chloro-2-(2,2,6,6-tetramethyl-4-morpholinyl)-4-pyrimidinyl]amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl-; 5-{[5-Chloro-2-(2,2,6,6-tetramethyl-4-morpholinyl)-4-pyrimidinyl]amino}-3-(3-hydroxy-3-methylbutyl)-1-methyl-1,3-dihydro-2H-benzimidazol-2-one. Grade: ≥98%. CAS No. 2253879-65-9. Molecular formula: C25H35ClN6O3. Mole weight: 503.04. | |
| BCL6-IN-5 | BCL6-IN-5 is a potent BCL6 inhibitor with a pIC50 of 5.82. (Exacted from patent WO2018215801A1, example 1n). Synonyms: 2H-Benzimidazol-2-one, 5-[(2,5-dichloro-4-pyrimidinyl)amino]-1,3-dihydro-3-(3-hydroxy-3-methylbutyl)-1-methyl-; 5-((2,5-Dichloropyrimidin-4-yl)amino)-3-(3-hydroxy-3-methylbutyl)-1-methyl-1H-benzo[d]imidazol-2(3H)-one; 5-[(2,5-Dichloro-4-pyrimidinyl)amino]-3-(3-hydroxy-3-methylbutyl)-1-methyl-1,3-dihydro-2H-benzimidazol-2-one. Grade: ≥95%. CAS No. 2253878-09-8. Molecular formula: C17H19Cl2N5O2. Mole weight: 396.27. | |
| BCL6-IN-7 | BCL6-IN-7 is a potent BCL6-corepressor interaction inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2097518-46-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115532. | |
| BC-LI-0186 | BC-LI-0186 is a potent and selective inhibitor of the interaction between Leucyl-tRNA synthetase (LRS) and RagD (IC50 of 46.11?nM). BC-LI-0186 inhibits the noncanonical mTORC1-activating function of LRS. Synonyms: 4-(4-Isopropyl-2,3-dimethyl-5-oxo-2,5-dihydro-1H-pyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide. Grade: 99%. CAS No. 695207-56-8. Molecular formula: C22H27N3O4S. Mole weight: 429.53. | |
| BC-LI-0186 | BC-LI-0186 is a potent and selective inhibitor of Leucyl-tRNA synthetase (LRS; LeuRS) and Ras-related GTP-binding protein D (RagD) interaction (IC50=46.11 nM). BC-LI-0186 competitively binds to the RagD interacting site of LRS (Kd=42.1 nM) and has on effects on LRS-Vps34, LRS-EPRS, RagB-RagD association, mTORC1 complex formation or the activities of 12 kinases. BC-LI-0186 can effectively suppress the activity of cancer-associated?MTOR?mutants and the growth of rapamycin-resistant cancer cells.?BC-LI-0186 is a promising agent for lung cancer research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 695207-56-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136265. | |
| Bcl-xL antagonist 2 | Bcl-xL antagonist 2 is a potent, selective and orally active antagonist of Bcl-XL with IC50 and Ki of 0.091 μM and 65 nM, respectively. Bcl-xL antagonist 2 promotes apoptosis of cancer cells, and has the potential to study chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma (NHL). Synonyms: 4-Thiazolecarboxylic acid, 2-[8-[(2-benzothiazolylamino)carbonyl]-3,4-dihydro-2(1H)-isoquinolinyl]-; 2-(8-(Benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)thiazole-4-carboxylic acid; 2-[8-(1,3-Benzothiazol-2-ylcarbamoyl)-3,4-dihydro-2(1H)-isoquinolinyl]-1,3-thiazole-4-carboxylic acid. Grade: ≥98%. CAS No. 1235032-75-3. Molecular formula: C21H16N4O3S2. Mole weight: 436.51. | |
| Bcl-xL Antibody [D4A3] | Bcl-xL Antibody [D4A3]. Group: Antibodies. Pack Sizes: 20ul. Product ID: F0129. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| BCMA72-80 | BCMA72-80 is a HLA-A2-specific B-cell maturation antigen (BCMA) peptide that has a high affinity for HLA-A2 and is used for the study of multiple myeloma and tumors expressing B-cell maturation antigen. Synonyms: L-Isoleucine, L-tyrosyl-L-leucyl-L-methionyl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-L-lysyl-; Tyr-Leu-Met-Phe-Leu-Leu-Arg-Lys-Ile. Grade: ≥98%. CAS No. 2293841-58-2. Molecular formula: C59H97N13O11S. Mole weight: 1196.55. | |
| BCMA72-80 acetate | BCMA72-80 acetate is an HLA-A2-specific B cell maturation antigen (BCMA) peptide with a high affinity for HLA-A2 and is used to study multiple myeloma and tumors expressing B cell maturation antigens. Synonyms: H-Tyr-Leu-Met-Phe-Leu-Leu-Arg-Lys-Ile-OH.CH3CO2H; L-tyrosyl-L-leucyl-L-methionyl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-L-lysyl-L-isoleucine acetic acid. Grade: ≥95%. Molecular formula: C61H101N13O13S. Mole weight: 1256.60. | |
| BCMCM-caged 8-Br-cAMP | BCMCM-caged 8-Br-cAMP is a caged precursor of 8-bromo cAMP with improved solubility in water or buffers. 8-Br-cAMP and a fluorescent coumarin analogue are released by irradiation. Synonyms: [6,7-Bis(carboxymethoxy)coumarin-4-yl]methyl-8-bromoadenosine-3',5'-cyclic monophosphate. Grade: ≥ 98% by HPLC. CAS No. 370091-64-8. Molecular formula: C24H21BrN5O14P. Mole weight: 714.33. | |
| BCMCM-caged 8-Br-cGMP | BCMCM-caged 8-Br-cGMP is a caged precursor of 8-bromo cGMP with improved solubility in water or buffers. 8-Br-cGMP and a fluorescent coumarin analogue are released by irradiation. Synonyms: [6,7-Bis(carboxymethoxy)coumarin-4-yl)methyl-8-bromoguanosine-3',5'-cyclic monophosphate. Grade: ≥ 98% by HPLC. CAS No. 370091-68-2. Molecular formula: C24H21BrN5O15P. Mole weight: 730.33. | |
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