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| Product | Description | |
|---|---|---|
| BC-11 hydrobromide | BC-11 hydrobromide is a selective TMPRSS2 inhibitor (TMPRSS2 is a key host cellular factor for viral entry and SARS-CoV-2 pathogenesis), and a selective urokinase (uPA) inhibitor (IC50=8.2 μM). BC-11 hydrobromide is cytotoxic to triple-negative MDA-MB231 breast cancer cells. BC-11 hydrobromide is used in research on viral infections and cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 443776-49-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-108447. |  |
| BC-1293 | BC-1293 is an inhibitor for E3 ligase subunit FBXO24. BC-1293 disrupts the interaction between FBXO24 and aspartyl-tRNA synthetase (DARS2) and increases the level of DARS2. BC-1293 increases levels of IL-1β, IL-9, MIP-2, and TNF α, and exhibits immunostimulatory activity in mice[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1219395-86-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-161901. | |
| BC-1382 | BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction (IC50? 5 nM).Anti-inflammatory activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1013753-99-5. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W062696. | |
| BC-1471 | BC-1471 is a STAMBP deubiquitinase inhibitor with an IC50 of 0.33 μM. BC-1471 can inhibit the activity of the NALP7 inflammasome. BC-1471 has anti-inflammatory activity and can be used for the research of inflammatory diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 896683-84-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-122883. | |
| BC1618 | BC1618, an orally active Fbxo48 inhibitory compound, stimulates Ampk-dependent signaling (via preventing activated pAmpkα from Fbxo48-mediated degradation). BC1618 promotes mitochondrial fission, facilitates autophagy and improves hepatic insulin sensitivity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2222094-18-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134656. | |
| BCA | BCA (Disodium bicinchoninate) is an orally active and non-competitive Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 value of 28 μM, a Ki value of 43 μM. BCA shows anticancer activity. BCA has the potential for the research of Alzheimer's disease (AD)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Disodium bicinchoninate. CAS No. 979-88-4. Pack Sizes: 10 mM * 1 mL in Water; 5 g; 10 g; 25 g; 50 g; 100 g; 500 g; 1 k g. Product ID: HY-15908. | |
| BCAA | It is a monocarboxylic acid, an organochlorine compound and a 2-bromocarboxylic acid. Category: Amino acids and derivatives. Synonyms: Bromochloroacetic acid. 5589-96-8. 2-bromo-2-chloroacetic acid. Acetic acid, bromochloro-. Keratins. CAS No. 69430-36-0. Product ID: API69430360. Molecular formula: C2H2BrClO2. Mole weight: 173.39. EINECS: 627-754-9. SMILES: C(C(=O)O)(Cl)Br. Appearance: Crystalline compound. Standard: In-house. |  |
| BCAA Powder (2:1:1) | BCAA Powder (2:1:1). |  CA, FL & NJ |
| b-Carotene 5,6-epoxide | b-Carotene 5,6-epoxide. Group: Biochemicals. Alternative Names: (5RS,6RS)-5,6-Epoxy-5,6-dihydro-b,b-carotene. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences. |  Worldwide |
| b-Caryophyllene oxide | b-Caryophyllene oxide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1139-30-6. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C15H24O. US Biological Life Sciences. | Worldwide |
| b-Casomorphin (1-3) acetate | b-Casomorphin (1-3) acetate is a tripeptide with opioid effects. Alternative Names: H-Tyr-Pro-Phe-OH.CH3CO2H; YPF acetate; L-tyrosyl-L-prolyl-L-phenylalanine acetic acid. Grades: ≥95%. CAS No. 2763583-71-5. Molecular formula: C23H27N3O5.C2H4O2. Mole weight: 485.53. |  |
| BCAT | BCAT. Alternative Names: Benzotriazole-1-Carboxamidinium Tosylate; 1H-Benzotriazole-1-carboximidamide, 4-methylbenzenesulfonate (1:1). Grades: 95%. CAS No. 163853-10-9. Molecular formula: C7H8N5.C7H7O3S. Mole weight: 333.37. | |
| BCATc Inhibitor 2 | BCATc Inhibitor 2 is a selective branched-chain aminotransferase (BCAT) inhibitor for research of neurodegenerative diseases. The IC50s of 0.2 μM, 0.8 μM and 3.0 μM for rat cytosolic isoenzyme rBCATc, human cytosolic isoenzyme hBCATc and rat mitochondrial isoenzyme rBCATm, respectively. BCATc, also called BCAT1, is in the cytoplasm[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 406191-34-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116044. | |
| BCAT-IN-1 | BCAT-IN-1 is a potent, selective and orally active inhibitor of BCATm, with a pIC50 of 7.3. BCAT-IN-1 shows 100-fold selectivity for BCATm over BCATc (pIC50=5.4). BCAT-IN-1 can be used for the research of metabolic diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1875078-61-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141668. | |
| BCAT-IN-2 | BCAT-IN-2 is a potent, selective and orally active inhibitor of mitochondrial branched-chain aminotransferase (BCATm), with a pIC50 of 7.3. BCAT-IN-2 shows selectivity for BCATm over BCATc (pIC50=6.6). BCAT-IN-2 can be used for the research of obesity and dislipidema[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1800024-45-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141669. | |
| bcbp | bcbp. CAS No. 858131-70-1. Molecular formula: C48H32N2. Mole weight: 636.8g/mol. IUPAC Name: 9-[4-[2-[2-(4-carbazol-9-ylphenyl)phenyl]phenyl]phenyl]carbazole. SMILES: C1=CC=C(C(=C1)C2=CC=C(C=C2)N3C4=CC=CC=C4C5=CC=CC=C53)C6=CC=CC=C6C7=CC=C(C=C7)N8C9=CC=CC=C9C1=CC=CC=C18. InChI: InChI=1S/C48H32N2/c1-3-15-39(37(13-1)33-25-29-35(30-26-33)49-45-21-9-5-17-41(45)42-18-6-10-22-46(42)49)40-16-4-2-14-38(40)34-27-31-36(32-28-34)50-47-23-11-7-19-43(47)44-20-8-12-24-48(44)50/h1-32H. |  |
| BCDMH | BCDMH. Alternative Names: Dantobrom(R) S; Dantoin(R) BCDMH; Dantobrom(R) TBS; 5-(bromomethyl)-5-(chloromethyl)hydantoin; BCDMH (1-BROMO-3-CHLORO-5,5-DIMETHYLHYDANTOIN). Grades: 0.99. CAS No. 32718-18-6. Molecular formula: C5H6BrClN2O2. Mole weight: 241.47. | |
| BCECF AM | BCECF AM ester is a membrane-permeable fluorescent indicator for intracellular pH. It is modified by intracellular esterases to produce BCECF, a polar fluorescein derivative that is retained by cells. Alternative Names: BCECF Acetoxymethyl ester; BCECF-acetoxymethyl; 2',7'-Bis(2-carboxyethyl)-5(6)-carboxyfluorescein acetoxymethyl ester; 3',6'-bis(acetyloxy)-5(or 6)-[[(acetyloxy)methoxy]carbonyl]-3-oxo-spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-dipropanoic acid, 2',7'-bis[(acetyloxy)methyl] ester. Grades: ≥95%. CAS No. 117464-70-7. Molecular formula: C42H40O21. Mole weight: 880.7. | |
| BCECF-AM | BCECF-AM. Group: Biochemicals. Grades: Purified. CAS No. 117464-70-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| b-Cellobiosyl azide | b-Cellobiosyl azide is a highly versatile biomedical compound, acting as a precursor for synthesizing glycoconjugates and glycosylated natural drugs. Leveraging its profound influence on protein function and stability, this remarkable compound has become extensively utilized in cutting-edge drug development and advanced pharmaceutical investigations. Alternative Names: 4-O-b-D-Glucopyranosyl-b-D-glucopyranosyl azide. CAS No. 69194-62-3. Molecular formula: C12H21N3O10. Mole weight: 367.3. | |
| BCH | BCH. Group: Biochemicals. Grades: Purified. CAS No. 20448-79-7. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| BCH | BCH (2-Amino-2-norbornanecarboxylic acid) is a selective and competitive inhibitor of large neutral amino acid transporter 1 (LAT1) significantly inhibit cellular uptake of amino acids and mTOR phosphorylation, which induces the suppression of cancer growth and apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Amino-2-norbornanecarboxylic acid; LAT1-IN-1. CAS No. 20448-79-7. Pack Sizes: 10 mM * 1 mL in Water; 50 mg; 100 mg. Product ID: HY-108540. | |
| b-Chloralose | b-Chloralose is a renowned compound employed for the research of sedation and anesthesia functioning as a central nervous system depressant. Uses: Anesthetics, intravenous. Alternative Names: beta-Chloralose; (R)-1-((2S,3aR,5R,6S,6aR)-6-hydroxy-2-(trichloromethyl)tetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethane-1,2-diol. CAS No. 16376-36-6. Molecular formula: C8H11Cl3O6. Mole weight: 309.53. | |
| b-Chloro-D-alanine 99+% (TLC) | b-Chloro-D-alanine 99+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| b-Chloro-DL-alanine hydrochloride 98+% (TLC) | b-Chloro-DL-alanine hydrochloride 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
| b-Chloro-L-alanine ≥95% (HPLC) | b-Chloro-L-alanine ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| b-Chloro-L-alanine hydrochloride | b-Chloro-L-alanine hydrochloride. Alternative Names: b-Chloro-L-Ala-OH HCl; (R)-2-Amino-3-chloropropionic acid hydrochloride; 3-Chloro-L-alanine Hydrochloride; beta-Chloro-L-alanine hydrochloride; L-Alanine, 3-chloro-, hydrochloride; 3-Chloro-l-alanine HCl; H-Ala(3-Cl)-OH HCl. Grades: ≥ 95% (HPLC). CAS No. 51887-89-9. Molecular formula: C3H6NO2Cl·HCl. Mole weight: 160.00. | |
| b-Chloro-L-alanine hydrochloride | b-Chloro-L-alanine hydrochloride. Group: Biochemicals. Alternative Names: b-Chloro-L-Ala-OH·HCl; (R)-2-Amino-3-chloropropionic acid hydrochloride. Grades: Highly Purified. CAS No. 51887-89-9. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C3H6NO2Cl·HCl. US Biological Life Sciences. | Worldwide |
| b-Chloro-L-alanine hydrochloride ≥95% (HPLC) | b-Chloro-L-alanine hydrochloride ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| b-Chloro-L-alanine methyl ester hydrochloride 98+% (TLC) | b-Chloro-L-alanine methyl ester hydrochloride 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| b-Cholestanol | b-Cholestanol. Group: Biochemicals. Alternative Names: 5a-Cholestan-3b-ol. Grades: Highly Purified. CAS No. 80-97-7. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C27H48O. US Biological Life Sciences. | Worldwide |
| BCI | BCI ((E)-BCI) is a DUSP6 (dual specificity phosphatase 6) inhibitor. BCI shows anti-inflammatory activity and decreases reactive oxygen species (ROS) production. BCI can be used in inflammatory disease research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (E)-BCI. CAS No. 1245792-51-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115502. | |
| BCI-137 | BCI-137 is a Argonaute 2 (AGO2) inhibitor. By inhibiting AGO2 function, reducing PTPN6/SHP-1 protein levels and enhancing STAT1 phosphorylation, BCI-137 restores the sensitivity of tumor cells to IFN-γ. BCI-137 effectively enhances the recruitment, activation and cytotoxicity of CD8+ T cells. BCI-137 exerts a synergistic effect with anti-PD-1 antibodies and significantly reduces tumor volume in preclinical mouse models. BCI-137 exhibits favorable safety profiles and does not cause significant weight loss or death in mice. BCI-137 can be used in research related to bladder cancer, colorectal cancer, melanoma and other related fields[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 112170-24-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-119024. | |
| BCI-215 | BCI-215 is a potent and tumor cell-selective dual specificity MAPK phosphatase (DUSP-MKP) inhibitor. BCI-215 has cytotoxicity for tumor cells but not normal cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1245792-67-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121087. | |
| BCI hydrochloride | BCI ((E)-BCI) hydrochloride is a DUSP6 (dual specificity phosphatase 6) inhibitor. BCI hydrochloride shows anti-inflammatory activity and decreases reactive oxygen species (ROS) production. BCI hydrochloride can be used in inflammatory disease research[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (E)-BCI hydrochloride. CAS No. 95130-23-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115502A. | |
| BCIP | BCIP(BCIP p-toluidine salt; X-phosphate p-toluidine salt) is an artificial chromogenic substrate used for the sensitive colorimetric detection of alkaline phosphatase activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BCIP p-toluidine salt; X-phosphate p-toluidine salt. CAS No. 6578-6-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-15909. | |
| BCIP Na) 5-Bromo-4-chloro-3-indolyl phosphate disodium salt | 1g Pack Size. Group: Building Blocks, Stains & Indicators. Formula: C8H4BrClNO4Na2P. CAS No. 102185-33-1. Prepack ID 67003351-1g. Molecular Weight 370.43. See USA prepack pricing. |  |
| BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine salt | 1g Pack Size. Group: Analytical Reagents, Biochemicals, Diagnostic Raw Materials. Formula: C8H5BrClNO4P ·C7H10N. CAS No. 6578-6-9. Prepack ID 21540524-1g. Molecular Weight 433.62. See USA prepack pricing. | |
| Bcl-2 Antibody [D6K15] | Bcl2,Bcl-2. Group: Antibodies. Alternative Names: Apoptosis regulator Bcl-2. CAS No. Pack Sizes: 20uL. Product ID: F2515. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| Bcl-2 Antibody [H20N17] | Bcl2,Bcl-2. Group: Antibodies. Alternative Names: Bcl-2. Pack Sizes: 20uL. Product ID: F0125. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Bcl-2 Binding Peptide, cell permeable | It is a peptide that binds to Bcl-2 with high affinity. It is derived from the BH3 domain (a death domain) of Bad, amino acid residues 140 to 165, and is cellular permeable due to the N-terminal modification by a decanoyl moiety. Alternative Names: Decanoyl-Lys-Asn-Leu-Trp-Ala-Ala-Gln-Arg-Tyr-Gly-Arg-Glu-Leu-Arg-Arg-Met-Ser-Asp-Glu-Phe-Glu-Gly-Ser-Phe-Lys-Gly-Leu-OH; N-decanoyl-L-lysyl-L-asparagyl-L-leucyl-L-tryptophyl-L-alanyl-L-alanyl-L-glutaminyl-L-arginyl-L-tyrosyl-glycyl-L-arginyl-L-alpha-glutamyl-L-leucyl-L-arginyl-L-arginyl-L-methionyl-L-seryl-L-alpha-aspartyl-L-alpha-glutamyl-L-phenylalanyl-L-alpha-glutamyl-glycyl-L-seryl-L-phenylalanyl-L-lysyl-glycyl-L-leucine. Grades: ≥95% by HPLC. Molecular formula: C153H240N44O42S. Mole weight: 3399.93. | |
| Bcl-2-like protein 1 (173-182) | Bcl-2-like protein 1 (173-182) is a 10-aa peptide. Bcl-2-like protein 1 is a potent inhibitor of cell death. It inhibits activation of caspases. Alternative Names: Bcl2-L-1 (173-182); Apoptosis regulator Bcl-X (173-182). | |
| BCL6-IN-13 | BCL6-IN-13 (compound I-94) inhibits BCL6 with an IC50 of 2 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2230407-20-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156595. | |
| BCL6-IN-7 | BCL6-IN-7 is a potent BCL6-corepressor interaction inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2097518-46-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115532. | |
| BC-LI-0186 | BC-LI-0186 is a potent and selective inhibitor of Leucyl-tRNA synthetase (LRS; LeuRS) and Ras-related GTP-binding protein D (RagD) interaction (IC50=46.11 nM). BC-LI-0186 competitively binds to the RagD interacting site of LRS (Kd=42.1 nM) and has on effects on LRS-Vps34, LRS-EPRS, RagB-RagD association, mTORC1 complex formation or the activities of 12 kinases. BC-LI-0186 can effectively suppress the activity of cancer-associated?MTOR?mutants and the growth of rapamycin-resistant cancer cells.?BC-LI-0186 is a promising agent for lung cancer research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 695207-56-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136265. | |
| BC-LI-0186 | BC-LI-0186 is a potent and selective inhibitor of the interaction between Leucyl-tRNA synthetase (LRS) and RagD (IC50 of 46.11?nM). BC-LI-0186 inhibits the noncanonical mTORC1-activating function of LRS. Alternative Names: 4-(4-Isopropyl-2,3-dimethyl-5-oxo-2,5-dihydro-1H-pyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide. Grades: 99%. CAS No. 695207-56-8. Molecular formula: C22H27N3O4S. Mole weight: 429.53. | |
| Bcl-xL Antibody [D4A3] | Bcl-xL Antibody [D4A3]. Group: Antibodies. Pack Sizes: 20ul. Product ID: F0129. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| BCMA72-80 | BCMA72-80 is a HLA-A2-specific B-cell maturation antigen (BCMA) peptide that has a high affinity for HLA-A2 and is used for the study of multiple myeloma and tumors expressing B-cell maturation antigen. Alternative Names: L-Isoleucine, L-tyrosyl-L-leucyl-L-methionyl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-L-lysyl-; Tyr-Leu-Met-Phe-Leu-Leu-Arg-Lys-Ile. Grades: ≥98%. CAS No. 2293841-58-2. Molecular formula: C59H97N13O11S. Mole weight: 1196.55. | |
| BCMA72-80 acetate | BCMA72-80 acetate is an HLA-A2-specific B cell maturation antigen (BCMA) peptide with a high affinity for HLA-A2 and is used to study multiple myeloma and tumors expressing B cell maturation antigens. Alternative Names: H-Tyr-Leu-Met-Phe-Leu-Leu-Arg-Lys-Ile-OH.CH3CO2H; L-tyrosyl-L-leucyl-L-methionyl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-L-lysyl-L-isoleucine acetic acid. Grades: ≥95%. Molecular formula: C61H101N13O13S. Mole weight: 1256.60. | |
| BCMCM-caged 8-Br-cAMP | BCMCM-caged 8-Br-cAMP is a caged precursor of 8-bromo cAMP with improved solubility in water or buffers. 8-Br-cAMP and a fluorescent coumarin analogue are released by irradiation. Alternative Names: [6,7-Bis(carboxymethoxy)coumarin-4-yl]methyl-8-bromoadenosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 370091-64-8. Molecular formula: C24H21BrN5O14P. Mole weight: 714.33. | |
| BCMCM-caged 8-Br-cGMP | BCMCM-caged 8-Br-cGMP is a caged precursor of 8-bromo cGMP with improved solubility in water or buffers. 8-Br-cGMP and a fluorescent coumarin analogue are released by irradiation. Alternative Names: [6,7-Bis(carboxymethoxy)coumarin-4-yl)methyl-8-bromoguanosine-3',5'-cyclic monophosphate. Grades: ≥ 98% by HPLC. CAS No. 370091-68-2. Molecular formula: C24H21BrN5O15P. Mole weight: 730.33. | |
| BCMCM-caged cGMP | BCMCM-caged cGMP is a caged precursor of cGMP, the second messenger, which has improved solubility in water or buffers. cGMP and a fluorescent coumarin analogue are released by irradiation. Alternative Names: cyclic guanosine-3',5'-monophosphate [6,7-bis(carboxymethoxy)coumarin-4-yl]methyl ester. Grades: ≥ 98% by HPLC. CAS No. 339291-52-0. Molecular formula: C24H22N5O15P. Mole weight: 651.43. | |
| BCN-amine (endo) | A heterobifunctional linker containing a BCN moiety for click chemistry and a primary amine. Grades: >95%. Molecular formula: C13H20N2O2. Mole weight: 236.31. | |
| BCN-CE-phosphoramidite | BCN-CE-phosphoramidite is an oligonucleotide modifier containing a BCN strained cyclooctyne structure. BCN-CE-phosphoramidite possesses bioorthogonal reactivity and bioconjugation capability[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1393524-83-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W714969A. | |
| BCN-endo-PEG2-maleimide | BCN-endo-PEG2-maleimide is an ADC linker containing 4 PEG units. Alternative Names: BCN-exo-PEG2-maleimide. CAS No. 2675364-08-4. Molecular formula: C24H33N3O7. Mole weight: 475.53. | |
| BCN-endo-PEG2-maleimide | BCN-endo-PEG2-maleimide is an ADC Linker containing 4 PEG units. BCN-endo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies. Uses: Scientific research. Category: Signaling pathways. CAS No. 2675364-08-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156311. | |
| BCN-exo-PEG3-maleimide | BCN-exo-PEG3-maleimide is an ADC Linker containing 3 PEG units. BCN-exo-PEG3-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which enables the further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies. Uses: Scientific research. Category: Signaling pathways. CAS No. 2919127-00-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156322. | |
| BCN-exo-PEG7-maleimide | BCN-exo-PEG7-maleimide is an ADC Linker containing 7 PEG units. BCN-exo-PEG7-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies. Uses: Scientific research. Category: Signaling pathways. CAS No. 2143965-47-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134734. | |
| BCN-HS-PEG2(vcPABC-MMAE)2 | BCN-HS-PEG2(vcPABC-MMAE)2 is a drug-linker conjugate for ADC consists an ADC linker and a tubulin polymerization inhibitor MMAE (HY-15162). BCN-HS-PEG2(vcPABC-MMAE)2 can be used in the synthesis of antibody-agent conjugates (ADCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2126083-82-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-164146. | |
| BCN-linker-DXd 2 | BCN-linker-DXd 2 is an ADC linker. BCN-linker-DXd 2 can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2566530-81-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-160098. | |
| BCN-OH | BCN-OH (endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne) is an alcohol functionalized cyclooctyne derivative. BCN-OH can act as a raw material for synthesizing other probes (such as BCN-TPP). BCN-OH is used to construct targeted probes by coupling with carboxyl-containing compounds (such as TPP-COOH). BCN-OH can be used as control reagent for BCN-TPP[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne. CAS No. 1263166-90-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 1 g. Product ID: HY-W111141. | |
| BCN-OH | BCN-OH is an alcohol functionalized cyclooctyne derivative. Alternative Names: (1alpha,8alpha,9beta)-Bicyclo[6.1.0]non-4-yn-9-ylmethanol; Rel-((1R,8S,9r)-bicyclo[6.1.0]non-4-yn-9-yl)methanol. Grades: 98%. CAS No. 1263166-90-0. Molecular formula: C10H14O. Mole weight: 150.22. | |
| BCN-PEG3-Biotin | BCN-PEG3-Biotin is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCN-PEG3-Biotin is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1263166-92-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130924. | |
| BCN-PEG3-OH | BCN-PEG3-OH is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCN-PEG3-OH is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2126749-77-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130925. | |
| BCN-PEG4-hydrazide | BCN-PEG4-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. BCN-PEG4-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2741640-52-6. Pack Sizes: 25 mg; 50 mg. Product ID: HY-133438. | |
| BCN-PEG4-NHS ester | BCN-endo-PEG4-NHS is an ADC Linker containing 4 PEG units. Alternative Names: BCN-endo-PEG4-NHS; BCN-endo-PEG4-SPA; BCN-exo-PEG4-NHS; rel-2,5-Dioxopyrrolidin-1-yl 1-((1R,8S,9s)-bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oate. Grades: ≥98%. CAS No. 1702356-19-1. Molecular formula: C26H38N2O10. Mole weight: 538.59. | |
| BCN-PEG4-NHS ester | BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1702356-19-1. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-133439. | |
| BCN-POE3-amine | endo-BCN-PEG2-NH2 is a polyethylene glycol (PEG)-based PROTAC linker. endo-BCN-PEG2-NH2 can be used in the synthesis of a series of PROTACs. Alternative Names: N-(1R,8S,9S)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl-1,8-diamino-3,6-dioxaoctane. Grades: >99%. CAS No. 1263166-93-3. Molecular formula: C17H28N2O4. Mole weight: 324.42. | |
| BCN-POE3-NH2 | BCN-POE3-NH2. CAS No. 1263166-93-3. Molecular formula: C17H28N2O4. Mole weight: 324.4g/mol. Purity: 95%+. IUPAC Name: [(1R,8S)-9-bicyclo[6.1.0]non-4-ynyl]methyl N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]carbamate. SMILES: C1CC2C(C2COC(=O)NCCOCCOCCN)CCC#C1. InChI: InChI=1S/C17H28N2O4/c18-7-9-21-11-12-22-10-8-19-17(20)23-13-16-14-5-3-1-2-4-6-15(14)16/h14-16H,3-13,18H2,(H,19,20)/t14-,15+,16?. | |
| b-Core-APE-HSA | b-Core-APE-HSA. | |
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