A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
BAY-985, a chemical probe, is a highly potent, orally active and selective ATP-competitive dual inhibitor of TBK1 and IKKε with IC50s of 2/30 and 2 nM for TBK1 (low/high ATP) and IKKε, respectively. Antitumor efficacy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2409479-29-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133117.
BAY-985
BAY-985 is a highly effective, orally active and selective TANK-binding kinase 1 (TBK1) and IκB kinase ε dual inhibitor, with anti-tumor activity. Synonyms: BAY985; GTPL10597; EX-A3294. Grade: ≥98% by HPLC. CAS No. 2409479-29-2. Molecular formula: C27H30F3N9O. Mole weight: 553.6.
Bayberry Bark Extract
Bayberry (Myrica cerifera) bark extract, 20% in water-glycerin, tonic, stimulating, and cleansing. CAS No. 529-44-2. Product ID: CI-SC-0872. Alfa Chemistry - ISO 9001:32057 Certified.
Bayberry Extract
Bayberry Extract. Applications: Used for health care products, dietary supplements, herb medecine and cosmetic industry. Group: Others. Synonyms: Bayberry Extract; 529-44-2; Myrica rubra sieb. Et Zucc. CAS No. 529-44-2. Purity: 50%-98% Myricitrin by HPLC, 5-10:1 by TLC. Appearance: Light yellow green fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Bark. Species: Myrica rubra sieb. Et Zucc. Bayberry Extract; 529-44-2; Myrica rubra sieb. Et Zucc; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-128.
Bayberry Myrica Rubra Fruit P.E. 80% Myricetin HPLC
Bayberry Myrica Rubra Fruit P.E. 80% Myricetin HPLC.
CA, FL & NJ
BayCysLT2
BayCysLT2 is a potent and selective antagonist for the CysLT2R, which attenuates exacerbation of infarction damage to the myocardium caused by endothelial CysLT2R overexpression. CysLT2R can influence myocardial damage post-ischemia/reperfusion by mediating leukocyte adhesion and infiltration. CysLT2R can further blockade post-infarction maintains its protective properties, indicating a possible therapeutic role for CysLT2R antagonism. BayCysLT2 inhibits radioligand binding of LTD4 to CysLT2 and CysLT1 receptor cell lines with IC50 values of 35 and >10,000 nM, respectively. Synonyms: CAY10633; 3-[[(3-carboxycyclohexyl)amino]carbonyl]-4-[3-[4-(4-phenoxybutoxy)phenyl]propoxy]-benzoic acid. Grade: ≥95%. CAS No. 712313-33-2. Molecular formula: C34H39NO8. Mole weight: 589.7.
Bayferrox
Bayferrox - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
North America & APAC
Bay K 8644
Bay K 8644 ((±)-Bay K 8644) is a racemate consisting of two isomers (R)-(+)-Bay-K-8644 and (S)-(-)-Bay-K-8644[1]. Bay K 8644 is a L-type Ca2+ channel agonist with an EC50 of 17.3 nM. Bay K 8644 increases Ca2+ influx through sarcolemmal Ca2+ channels by increasing the open time of the channel. Bay K 8644 has vasoconstrictive effects[2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (±)-Bay K 8644. CAS No. 71145-03-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10588.
Bay K 8644
Bay K 8644 is a racemate. Bay K 8644 is a potent, selective activator of L-type Ca2+ channel with IC50 of 17.3 nM. Group: Inhibitors. CAS No. 71145-03-4. Pack Sizes: 5mg. Product ID: S7924. Formula: C16H15F3N2O4. Smiles: CC1=C(C(C(=C(N1)C)[N+](=O)[O-])C2=CC=CC=C2C(F)(F)F)C(=O)OC. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Bay Laurel Extract
Bay Laurel (Laurus nobilis) leaf extract, 20% in water-glycerin, aromatic, anti-dandruff, astringent, and soothing. CAS No. 84603-73-6. Product ID: CI-SC-0833. Alfa Chemistry - ISO 9001:32057 Certified.
Bay leaf/fruit oil
Bay leaf/fruit oil. Alternative Names: Pimenta racemosa mill. leaf/fruit oil. CAS No. 8006-78-8. Purity: 100% Pure and Natural. Product ID: FFC-AR-8006788. Alfa Chemistry - ISO 9001:32057 Certified.
Bayogenin
Bayogenin. Group: Biochemicals. Grades: Plant Grade. CAS No. 6989-24-8. Pack Sizes: 10mg. Molecular Formula: C30H48O5, Molecular Weight: 488.7. US Biological Life Sciences.
Worldwide
Bayogenin 3-O- β-D-glucopyranoside
Bayogenin 3-O- β-D-glucopyranoside. Group: Biochemicals. CAS No. 104513-86-2. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Bay Oil Natural
Bay Oil Natural. CAS No. MIXTURE. Kosher: Y. VIGON Item # 508413. Categories: Speciality Ingredients Suppliers, Flavors, Fragrances, Perfumers, Cosmetics, Aromatherapy, Essential Oils.
America & Internationally
Bay Oil Terpeneless
Bay Oil Terpeneless. CAS No. 68916-05-2. Kosher: Y. VIGON Item # 501494. Categories: Speciality Ingredients Suppliers, Flavors, Fragrances, Perfumers, Cosmetics.
America & Internationally
Bay oil terpenes
Bay oil terpenes. CAS No. 91721-75-4. Purity: 100% Pure and Natural. Product ID: FFC-AR-91721754. Alfa Chemistry - ISO 9001:32057 Certified.
BAY-u 3405
BAY-u 3405. Group: Biochemicals. Grades: Purified. CAS No. 116649-85-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
BAY-u 9773
BAY-u 9773. Group: Biochemicals. Grades: Purified. CAS No. 154978-38-8. Pack Sizes: 50ug. US Biological Life Sciences.
Worldwide
BAY-u 9773
BAY-u 9773 is a non-selective cysteinyl leukotriene receptor antagonist displaying equal affinity for both CysLT1 and CysLT2 receptors (pKB = 6.8 and 6.5, respectively). BAY-u 9773 was investigated to inhibit bronchial and venous muscle contractions in human muscle preparations. BAY-u 9773 also acts as a competitive antagonist of LTC4- and LTE4-induced contractions of the guinea pig trachea. Synonyms: BAYu9773; BAY-u9773; BAY u9773. 4-[[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]thio]benzoic acid; 6(R)-(4-Carboxyphenylthio)-5(S)-hydroxy-7(E),9(E),11(E),14(Z)-eicosatetraenoic acid. CAS No. 154978-38-8. Molecular formula: C27H36O5S. Mole weight: 472.64.
BAY-X 1005
BAY-X 1005. Group: Biochemicals. Grades: Purified. CAS No. 128253-31-6. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
BAY-X-1005
BAY-X 1005 is a potent and selective FLAP (5-lipoxygenase-activating protein) inhibitor. BAY-X 1005 is also a selective inhibitor of leukotriene synthesis. BAY-X1005 inhibited LTB4 synthesis with IC50 values of 220 nM for isolated PMNL of human and inhibited LTC4 synthesis with IC50 value of 210 nM in mouse macrophages. Phase-III for Myocardial infarction in USA was suspended in 2006. Uses: Myocardial infarction. Synonyms: BAY-X-1005; BAY X 1005; BAYX1005; Veliflapon; DG-031; DG 031; DG031; (2R)-2-cyclopentyl-2-[4-(quinolin-2-ylmethoxy)phenyl]acetic acid. Grade: >98 %. CAS No. 128253-31-6. Molecular formula: C23H23NO3. Mole weight: 361.43.
BAY-Y 3118
BAY-Y 3118 is a 4-quinolone with outstanding antimicrobial activity against Gramnegative and Gram-positive pathogens as well as anaerobic and intracellular bacteria and might be an important contribution to progress in anti-infective therapy. Synonyms: 7-[(4aS,7aS)-1,2,3,4,4a,5,7,7a-octahydropyrrolo[3,4-b]pyridin-6-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid; 1-cyclopropyl-7-(2,8-diazabicyclo(4.3.0)non-8-yl)-6-fluoro-8-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid hydrochloride; Bay y 3118; Bay Y3118; Bay-Y3118. CAS No. 151213-16-0. Molecular formula: C20H21ClFN3O3. Mole weight: 405.85.
BAZ1A-IN-1
BAZ1A-IN-1 is a potent BAZ1A (bromodomain-containing protein) inhibitor with a KD of 0.52 μM against BAZ1A bromodomain. It has good anti-viability activity against cancer cell lines with a high expression level of BAZ1A, but weak or no activity against cancer cells with a low expression level of BAZ1A. Synonyms: Urea, N-(3-nitrophenyl)-N'-(4-phenyl-2-thiazolyl)-. Grade: ≥95%. CAS No. 941521-45-5. Molecular formula: C16H12N4O3S. Mole weight: 340.36.
BAZ1A-IN-1
BAZ1A-IN-1 is a potent inhibitor of BAZ1A (bromodomain-containing protein). BAZ1A-IN-1 shows a KD value of 0.52 μM against BAZ1A bromodomain. BAZ1A-IN-1 shows good anti-viability activity against cancer cell lines expressing a high level of BAZ1A, but weak or no activity against cancer cells with a low expression level of BAZ1A[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 941521-45-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141890.
BAZ2-ICR
BAZ2-ICR is a potent, selective, cell active and orally active BAZ2A/B bromodomains inhibitor with IC50s of 130 nM and 180 nM, and Kds of 109 nM and 170 nM, respectively. BAZ2-ICR shows 10-15-fold selectivity for binding BAZ2A/B over CECR2 and >100-fold selectivity over all other bromodomains. BAZ2-ICR is an epigenetic chemical probe[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1665195-94-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g; 2 g. Product ID: HY-19336.
BAZ2-ICR
BAZ2-ICR is a bromodomain inhibitor with IC50 of 130 nM for BAZ2A and IC50 of 180 nM for BAZ2B. It demonstrates 15-fold selectivity for binding BAZ2A/B over CECR2 and >100-fold selectivity over all other bromodomains. Synonyms: 4-(4-(1-methyl-1H-pyrazol-4-yl)-1-(2-(1-methyl-1H-pyrazol-4-yl)ethyl)-1H-imidazol-5-yl)benzonitrile; BAZ2ICR. Grade: ≥98%. CAS No. 1665195-94-7. Molecular formula: C20H19N7. Mole weight: 357.41.
Bazedoxifene
Bazedoxifene (TSE-424) is an oral, BBB-penetrant nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene can be used for the research of osteoporosis. Bazedoxifene also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TSE-424. CAS No. 198481-32-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0031.
Bazedoxifene-4'-Glucuronide
Bazedoxifene-4'-Glucuronide is a metabolite of Bazedoxifene. Synonyms: Bazedoxifene 4'-β-D-Glucuronide; [1-[[4-[2-(Hexahydro-1H-azepin-1-yl)ethoxy]phenyl]Methyl]-5-hydroxy-3-Methyl-1H-indol-2-yl]phenyl β-D-Glucopyranosiduronic Acid. Grade: 95%. CAS No. 328933-64-8. Molecular formula: C36H42N2O9. Mole weight: 646.74.
Bazedoxifene-5-Glucuronide
Bazedoxifene-5-Glucuronide is a metabolite of Bazedoxifene. Synonyms: Bazedoxifene 5-β-D-Glucuronide; 1-[[4-[2-(Hexahydro-1H-azepin-1-yl)ethoxy]phenyl]Methyl]-2-(4-hydroxyphenyl)-3-Methyl-1H-indol-5-yl β-D-Glucopyranosiduronic Acid. Grade: 95%. CAS No. 328933-56-8. Molecular formula: C36H42N2O9. Mole weight: 646.74.
Bazedoxifene acetate
Bazedoxifene acetate, also called as TSE424 or WAY-140424, is a selective nonsteroidal estrogen receptor modulator (SERM) with antiosteoporotic activity (ERα: IC50= 26 nM; ERβ= 99 nM). Uses: Bone density conservation agents. Synonyms: TSE 424; TSE-424; TSE424; WAY-140424; WAY 140424; WAY140424. Grade: 98%. CAS No. 198481-33-3. Molecular formula: C32H38N2O5. Mole weight: 530.66.
Bazedoxifene acetate
Bazedoxifene acetate (TSE-424 acetate) is an oral, nonsteroidal selective estrogen receptor modulator (SERM), with IC50s of 23 nM and 99 nM for ERα and ERβ, respectively. Bazedoxifene acetate can be used for the research of osteoporosis. Bazedoxifene acetate also acts as an inhibitor of IL-6/GP130 protein-protein interactions and can be used for the research of pancreatic cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TSE-424 acetate. CAS No. 198481-33-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-A0036.
Bazedoxifene Acetate
Bazedoxifene Acetate is a nonsteroidal selective estrogen receptor modulator (SERM). Bazedoxifene Acetate is used as an antiosteoporotic. Group: Biochemicals. Alternative Names: 1-[[4-[2- (Hexahydro-1H-azepin-1-yl) ethoxy]phenyl]methyl]-2- (4-hydroxyphenyl) -3-methyl-. Grades: Highly Purified. CAS No. 198481-33-3. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Bazedoxifene-[d4] Acetate
Bazedoxifene-[d4] Acetate is an isotope labelled Bazedoxifene Acetate, which is a nonsteroidal selective estrogen receptor modulator for the treatment of osteoporosis in postmenopausal women. Synonyms: Bazedoxifene-d4 Acetate; TSE 424-d4; Viviant-d4; WAY-TES 424-d4. Grade: >95%; 98% atom D. CAS No. 1133695-49-4. Molecular formula: C32H38N2O5. Mole weight: 534.7.
Bazedoxifene hydrochloride
Bazedoxifene is a third generation selective estrogen receptor modulator (SERM). Bazedoxifene does not stimulate ERα mediated transcriptional activity and acts as an antagonist to estradiol in cultured breast cancer (bMCF-7) cells. Uses: Bone density conservation agents. Synonyms: TSE-424 hydrochloride; 1-(4-(2-(azepan-1-yl)ethoxy)benzyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol hydrochloride; 1H-Indol-5-ol, 1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-, hydrochloride (1:1). Grade: >98%. CAS No. 198480-56-7. Molecular formula: C30H34N2O3.HCl. Mole weight: 507.06.
Bazedoxifene Impurity 1
Bazedoxifene Impurity 1. Uses: For analytical and research use. Alternative Names: 3-(4-(2-(azepan-1-yl)ethoxy)benzyl)-2-(4-hydroxyphenyl)-3-methyl-3H-indol-5-ol. Molecular formula: C30H34N2O3. Mole weight: 470.6. Catalog: APB03660.
Bazedoxifene Impurity 1
Bazedoxifene Impurity 1. Uses: For analytical and research use. CAS No. 91444-54-1. Molecular formula: C15H13NO2. Mole weight: 239.27. Catalog: APB91444541.
Bazedoxifene Impurity 2
Bazedoxifene Impurity 2. Uses: For analytical and research use. Alternative Names: (4-(2-(azepan-1-yl)ethoxy)phenyl)methanol. Molecular formula: C15H23NO2. Mole weight: 249.35. Catalog: APB03661.
Bazedoxifene Impurity 3
Bazedoxifene Impurity 3. Uses: For analytical and research use. Alternative Names: 5-(benzyloxy)-2-(4-(benzyloxy)phenyl)-3-methyl-3H-indole. Molecular formula: C29H25NO2. Mole weight: 419.51. Catalog: APB03659.
Bazedoxifene Impurity 3
Bazedoxifene Impurity 3 is a metabolite of Bazedoxifene. Synonyms: Des(1-azepanyl)ethyl Bazedoxifene; 2-(4-Hydroxyphenyl)-1-[(4-hydroxyphenyl)methyl]-3-methyl-1H-Indol-5-ol; 1-(4-Hydroxybenzyl)-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol. Grade: > 95%. CAS No. 104599-10-2. Molecular formula: C22H19NO3. Mole weight: 345.40.
Bazedoxifene Impurity 4
Bazedoxifene Impurity 4 is a metabolite of Bazedoxifene. Synonyms: 5-O-Benzylbazedoxifene; 4-[1-[[4-[2-(Hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-3-methyl-5-(phenylmethoxy)-1H-indol-2-yl]phenol. Grade: > 95%. CAS No. 328933-58-0. Molecular formula: C37H40N2O3. Mole weight: 560.74.
Bazedoxifene Impurity 4
Bazedoxifene Impurity 4. Uses: For analytical and research use. CAS No. 104599-10-2. Molecular formula: C22H19NO3. Mole weight: 345.4. Catalog: APB104599102.
Bazedoxifene Impurity 5
Bazedoxifene Impurity 5. Uses: For analytical and research use. CAS No. 1381947-93-8. Molecular formula: C37H40N2O3. Mole weight: 560.74. Catalog: APB1381947938.
Bazedoxifene Impurity 6
Bazedoxifene Impurity 6. Uses: For analytical and research use. CAS No. 328933-58-0. Molecular formula: C37H40N2O3. Mole weight: 560.74. Catalog: APB328933580.
Bazedoxifene Impurity 7
Bazedoxifene Impurity 7. Uses: For analytical and research use. CAS No. 198480-21-6. Molecular formula: C44H46N2O3. Mole weight: 650.86. Catalog: APB198480216.
Bazedoxifene-N-Oxide
Bazedoxifene N-Oxide is a metabolite of Bazedoxifene. Synonyms: 1-[[4-[2-(Hexahydro-1-oxido-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol. Grade: > 95%. CAS No. 1174289-22-5. Molecular formula: C30H34N2O4. Mole weight: 486.62.
BB-22 3-Carboxyindole Metabolite
BB-22 3-Carboxyindole Metabolite is an intermediate of MDMB-CHMICA (M199520). MDMB-CHMICA is an analogue of N-[(1S)-1-(Aminocarbonyl)-2-methylpropyl]-1-[(4-fluorophenyl)methyl]-1H-indazole-3-carboxamide (A603135), an indazole derivative developed as a CB1 receptor modulator used in the treatment of CB1-mediated diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 858515-71-6. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C16H19NO2. US Biological Life Sciences.
Worldwide
Bb-AMP4
Bb-AMP4 is an antimicrobial peptide produced by Bellamya bengalensis (a fresh water snail). It has antibacterial activity. It contains an intramolecular disulfide bond. Synonyms: Bellamya bengalensis antimicrobial peptide 4; Pro-Ser-Cys-Val-Cys-Ser-Gly-Phe-Glu-Thr-Ser-Gly-Ile-His-Phe-Cys. Grade: >98%. Molecular formula: C71H102N18O23S3. Mole weight: 1671.88.
BBC0403
BBC0403 is a selective BRD2 inhibitor with Kds of 7.64 μM and 41.37 μM for BRD2 (BD2) and BRD2 (BD1), respectively. BBC0403 exhibitS higher binding specificity for BRD2 compared to BRD3 and BRD4. BBC0403 has the potential for osteoarthritis (OA) research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2644662-83-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-162514.
BB-Cl-Amidine
BB-Cl-Amidine is a peptidylarginine deminase (PAD) inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 1802637-39-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111347.
BB-Cl-Amidine hydrochloride
BB-Cl-Amidine hydrochloride is a peptidylarginine deminase (PAD) inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2436747-41-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111347A.
BB-K 6 N-(Benzyloxy) Carbamate
BB-K 6 N-(Benzyloxy) Carbamate is an intermediate in the synthesis of BB-K 6, a semi-synthetic aminoglycoside antibiotic derived from Kanamycin A. Synonyms: Benzyl ((S)-4-((((2R,3S,4S,5R,6R)-6-(((1R,2R,3S,4R,6S)-4,6-diamino-3-(((2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl)amino)-3-hydroxy-4-oxobutyl)carbamate. Molecular formula: C30H49N5O15. Mole weight: 719.73.
BB-K 6 Sulfate Salt
BB-K 6 is a semi-synthetic aminoglycoside antibiotic derived from Kanamycin A. Synonyms: (S)-O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-[(4-amino-2-hydroxy-1-oxobutyl)amino]-6-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine Sulfate Salt; O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-[[(2S)-4-amino-2-hydroxy-1-oxobutyl]amino]-6-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine Sulfate Salt; Antibiotic BB-K 6 Sulfate Salt; Amikacin EP Impurity E Sulfate. Grade: 97%. Molecular formula: C22H43N5O13.xH2SO4. Mole weight: 585.60 (free base).
BBO-10203 is a potent inhibitor of PI3Kα and KRASG12C, selectively and covalently binding to Cys242 in the RAS-Binding Domain of PI3Kα, and inhibiting both the GTP-bound and GDP-bound states of KRASG12C with an IC50 of 0.031 nM and an EC50 of 0.02 nM. BBO-10203 disrupts the interaction between RAS isoforms and PI3Kα, leading to the inhibition of RAS-mediated PI3Kα activation, and reduces pERK expression, cell growth, and induces G1 arrest and apoptosis. BBO-10203 can be used for the research of breast cancer, colorectal cancer, and non-small cell lung cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2971769-60-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-159852.
BBO-11818
BBO-11818 is an orally active, highly selective (relative to NRAS and HRAS), non-covalent pan-KRAS inhibitor (IC50=28-120 nM). BBO-11818 specifically binds to the Switch-II/Helix 3 pocket, disrupts the KRAS:RAF1 interaction by inducing conformational changes, and blocks the MAPK signaling pathway. BBO-11818 exhibits significant anti-tumor activity, which not only inhibits cell proliferation and induces apoptosis, but also drives tumor regression in xenograft models. BBO-11818 produces synergistic effects when combined with Cetuximab (HY-P9905), anti-PD-1 antibody or PI3Kα inhibitor. BBO-11818 is used in the research of KRAS mutation-related malignancies such as pancreatic cancer, non-small cell lung cancer and colorectal cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3029443-36-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-181420A.
BBO-8520
BBO-8520 is a direct small molecule covalent inhibitor targeting KRAS G12C with high oral availability. BBO-8520 has the characteristics of KRAS G12C (OFF) inhibitor and the function of blocking KRASG12C (ON) signal. BBO-8520 inhibits cell proliferation by inhibiting KRAS G12C (ON) by binding GTP protein. BBO-8520 can block RAS-RAF1 interaction and return KRAS G12C to the inactive (OFF) state. BBO-8520 can be used for the research of cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2893809-51-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158107.
BBQ-650-DT CEP
BBQ-650-DT CEP is a revolutionary chemical amalgamation employed with an aim to precisely target cancerous cells. Its exceptionally selective inhibition explicitly curtails the activity of an intricate protein implicated in the pernicious development of tumors. Synonyms: 5'-Dimethoxytrityloxy-5-[6-(9-[4-nitro-2',5'-dimethoxyazobenz-4'-yldiazo]-julolidin-8-oxy)-hexylamidoethyl-3-acrylimido]-2'-deoxyUridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grade: 95%. CAS No. 905554-46-3. Molecular formula: C76H89N12O15P. Mole weight: 1441.57.
BBQ-650® CPG
BBQ-650® CPG is a pathbreaking biomedical solution, celebrated for its tremendous potential in cancer immunotherapy. At its heart is the synthetic CpG DNA, which gets its unique edge from invoking Toll-like receptor 9 (TLR9) on immune cells, causing a seismic immune response against malignancies. In clinical trials, BBQ-650® CPG has been found to effectively thwart various cancers such as melanoma and non-small cell lung cancer. Its promising potency is now the spotlight of scientific curiosity. Synonyms: BBQ-650® CPG 1000Å; 5-O-(Dimethoxytrityl)-1-[9-[4-nitro-2',5'-dimethoxy-azobenz-4'-yl)-diazo]-julolidine-8]-O-pentyl-3-O-glycolate-CPG; BBQ-650 CPG.
b-Bromoethylphosphoryl dichloride. Group: Biochemicals. Alternative Names: Phosphorodichloridic acid 2-bromoethyl ester; 2-Bromoethyl dichlorophosphate; 2-Bromoethyl phosphorodichloridate. Grades: Highly Purified. CAS No. 4167-2-6. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C2H4BrCl2O2P. US Biological Life Sciences.
Worldwide
B Bronze strip, 7.5mm (0.3in) width x 0.8mm (0.032in) thick x random length coil
B Bronze strip, 7.5mm (0.3in) width x 0.8mm (0.032in) thick x random length coil.
BBS 4
BBS4, inhibits the dimerization of iNOS monomers, is a potent, orally active and selective inducible nitric oxide synthase dimerization inhibitor. Uses: Inos dimmerization inbibitor. Synonyms: BBS4; BBS-4; (R)-1-(2-(1H-imidazol-1-yl)-6-methylpyrimidin-4-yl)-N-(2-(benzo[d][1,3]dioxol-5-yl)ethyl)pyrrolidine-2-carboxamide. Grade: ≥98%. CAS No. 402934-09-2. Molecular formula: C22H24N6O3. Mole weight: 420.47.
BBT
BBT is an enhancer of impaired glucose-stimulated insulin secretion (GSIS). BBT improves glucose homeostasis by ameliorating β-cell dysfunction in type 2 diabetic mice. CAS No. 445000-45-3. Molecular formula: C18H12BrNO2S. Mole weight: 386.3.
BBT-176
BBT-176 is an orally effective EGFR inhibitor. BBT-176 has inhibitory activity against multiple EGFR C797S mutant cell lines. BBT-176 is commonly used in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2254805-44-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153974.
BBT594
BBT594, also called as NVP-BBT594, a dihydroindole compound, originally developed as an inhibitor of wild-type and T315I-mutant BCR-ABL1, and then subsequently was shown to inhibit JAK2 activity (IC50 = 8nM ~ 29nM in murine models). The Type II JAK2 inhibitor NVP-BBT594 also displayed potent inhibition of HCV activity (EC50 < 1.5 mM). BBT594 impairs GDNF-RET signaling, a promising therapeutic target to enhance the sensitivity to aromatase inhibitor (AI) treatment and revert AI resistance in ER+ breast cancer cells. It also impairs GDNF-dependent growth of MCF7-LTED cells. Synonyms: 5-(6-acetamidopyrimidin-4-yl)oxy-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-2,3-dihydroindole-1-carboxamide; BBT-594; BBT-594; BBT-594; NVP-BBT594; NVP BBT594; NVP BBT-594GTPL7584; SCHEMBL12972358; 5-(6-acetamidopyrimidin-4-yl)oxy-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-2,3-dihydroindole-1-carboxamide. CAS No. 882405-89-2. Molecular formula: C28H30F3N7O3. Mole weight: 569.59.
BBT594
BBT594 is a potent receptor tyrosine kinase RET inhibitor, used for cancer treatment. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NVP-BBT594. CAS No. 882405-89-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18840.
b,b-Trehalose
b,b-Trehalose is a naturally occurring disaccharide assuming a pivotal function renowned for its employ as a stabilizer and shielder in diverse medicinal formulations and interventions. Synonyms: beta,beta-trehalose; beta-D-glucopyranosyl beta-D-glucopyranoside; (2R,2'R,3S,3'S,4S,4'S,5R,5'R,6S,6'S)-6,6'-oxybis(2-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol). CAS No. 499-23-0. Molecular formula: C12H22O11. Mole weight: 342.30.
Bbv12 I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 3-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. GWGCW↑C C↓WCGWG. Activity: 2000u.a./ml. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: Bacillus brevis 12. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1032RE.
BC 11-38
BC 11-38 is a potent and selective phosphodiesterase (PDE) 11 inhibitor (IC50 = 0.28 μM for PDE11; IC50 values are >100 μM for PDE1 - PDE10). BC 11-38 increases cAMP and cortisol levels in H295R human adenocarcinoma cells. Synonyms: BC11-38; BC 11-38; BC-11-38. 6,7-Dihydro-3-phenyl-2-(propylthio)thieno[3,2-d]pyrimidin-4(3H)one; 3-phenyl-2-propylsulfanyl-6,7-dihydrothieno[3,2-d]pyrimidin-4-one. Grade: ≥98% by HPLC. CAS No. 686770-80-9. Molecular formula: C15H16N2OS2. Mole weight: 304.43.
BC 11-38
BC 11-38. Group: Biochemicals. Grades: Purified. CAS No. 686770-80-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.