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BCN-OH (endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne) is an alcohol functionalized cyclooctyne derivative. BCN-OH can act as a raw material for synthesizing other probes (such as BCN-TPP). BCN-OH is used to construct targeted probes by coupling with carboxyl-containing compounds (such as TPP-COOH). BCN-OH can be used as control reagent for BCN-TPP[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: endo-9-Hydroxymethylbicyclo[6.1.0]non-4-yne. CAS No. 1263166-90-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 1 g. Product ID: HY-W111141.
BCN-OH
BCN-OH is an alcohol functionalized cyclooctyne derivative. Synonyms: (1alpha,8alpha,9beta)-Bicyclo[6.1.0]non-4-yn-9-ylmethanol; Rel-((1R,8S,9r)-bicyclo[6.1.0]non-4-yn-9-yl)methanol. Grade: 98%. CAS No. 1263166-90-0. Molecular formula: C10H14O. Mole weight: 150.22.
BCN-PEG3-Biotin is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCN-PEG3-Biotin is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1263166-92-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130924.
BCN-PEG3-Biotin (endo)
A biotinylation reagent containing a BCN moiety for click chemistry. Grade: >90%. Molecular formula: C29H46N4O7S. Mole weight: 594.31.
BCN-PEG3-Biotin (exo)
A biotinylation reagent with a BCN moiety for click chemistry. Grade: >90%. Molecular formula: C29H46N4O7S. Mole weight: 594.31.
BCN-PEG3-OH
BCN-PEG3-OH is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCN-PEG3-OH is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2126749-77-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130925.
BCN-PEG4-hydrazide
BCN-PEG4-hydrazide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. BCN-PEG4-hydrazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2741640-52-6. Pack Sizes: 25 mg; 50 mg. Product ID: HY-133438.
BCN-PEG4-NHS ester
BCN-endo-PEG4-NHS is an ADC Linker containing 4 PEG units. Synonyms: BCN-endo-PEG4-NHS; BCN-endo-PEG4-SPA; BCN-exo-PEG4-NHS; rel-2,5-Dioxopyrrolidin-1-yl 1-((1R,8S,9s)-bicyclo[6.1.0]non-4-yn-9-yl)-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oate. Grade: ≥98%. CAS No. 1702356-19-1. Molecular formula: C26H38N2O10. Mole weight: 538.59.
BCN-PEG4-NHS ester
BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1702356-19-1. Pack Sizes: 10 mg; 25 mg; 50 mg. Product ID: HY-133439.
BCR/ABL 210 kD fusion protein (21-29) is a 9-aa peptide. The hallmark of chronic myelogenous leukaemia (CML) is the presence of the Philadelphia chromosome and its resultant fusion message, BCR-ABL, and fusion protein, p210.
BCR/ABL 210 kD fusion protein (259-269)
BCR/ABL 210 kD fusion protein (259-269) is a 11-aa peptide. The hallmark of chronic myelogenous leukaemia (CML) is the presence of the Philadelphia chromosome and its resultant fusion message, BCR-ABL, and fusion protein, p210.
BCR-ABL fusion protein (b3a2) (920-936)
BCR-ABL fusion protein (b3a2) (920-936) is a peptide corresponding to residues 9220-936 of BCR-ABL fusion protein (b3a2). It is found that b3a2 peptide-specific CD4-positive T-helper cells were able to recognize p210b3a2-positive chronic myelogenous leukemia (CML) blasts in a DR4 restricted manner.
BCR-ABL fusion protein (b3a2) (922-930)
BCR-ABL fusion protein (b3a2) (922-930) is a peptide corresponding to residues 922-930 of BCR-ABL fusion protein (b3a2). It is found that b3a2 peptide-specific CD4-positive T-helper cells were able to recognize p210b3a2-positive chronic myelogenous leukemia (CML) blasts in a DR4 restricted manner.
BCR-ABL fusion protein (b3a2) (926-934)
BCR-ABL fusion protein (b3a2) (926-934) is a peptide corresponding to residues 926-934 of BCR-ABL fusion protein (b3a2). It is found that b3a2 peptide-specific CD4-positive T-helper cells were able to recognize p210b3a2-positive chronic myelogenous leukemia (CML) blasts in a DR4 restricted manner.
BCR-ABL-IN-1
BCR-ABL-IN-1, a BCR-ABL tyrosine kinase inhibitor with a pIC50 of 6.46, may be used in the study of chronic myelogenous leukemia. Synonyms: N-[4-[1-(3-Aminopropyl)-1H-indole-4-yl]pyrimidine-2-yl]-3-(1,1,2,2-tetrafluoroethoxy)aniline; 1H-Indole-1-propanamine, 4-[2-[[3-(1,1,2,2-tetrafluoroethoxy)phenyl]amino]-4-pyrimidinyl]-; 4-[1-(3-Aminopropyl)-1H-indol-4-yl]-N-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-pyrimidinamine. Grade: ≥98%. CAS No. 188260-50-6. Molecular formula: C23H21F4N5O. Mole weight: 459.44.
BCR-ABL-IN-2
BCR-ABL-IN-2 is a BCR-ABL1 tyrosine kinase inhibitor, with IC50s of 57 and 773 nM for ABL1 native and ABL1T315I, respectively. Synonyms: (S)-6-(3-(tert-butyl)-5-(3-(2,3-dichlorophenyl)ureido)-1H-pyrazol-1-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 3-Isoquinolinecarboxylic acid, 6-[5-[[[(2,3-dichlorophenyl)amino]carbonyl]amino]-3-(1,1-dimethylethyl)-1H-pyrazol-1-yl]-1,2,3,4-tetrahydro-, (3S)-. Grade: ≥95%. CAS No. 897369-18-5. Molecular formula: C24H25Cl2N5O3. Mole weight: 502.39.
BCR-ABL-IN-3
BCR-ABL-IN-3 is a potent and irreversible inhibitor of Bcr-Abl with an IC50 of ≤100 nM for Ba/F3Bcr-AblT3151. It has anti-cancer activity. Synonyms: 3-Pyridinecarboxamide, N-[4-(chlorodifluoromethoxy)phenyl]-6-[(3R)-3-hydroxy-1-pyrrolidinyl]-5-(4-isothiazolyl)-. CAS No. 2240191-12-0. Molecular formula: C20H17ClF2N4O3S. Mole weight: 466.89.
Bcrp-IN-1
Bcrp-IN-1 is an inhibitor of breast cancer resistance protein (BCRP) with an IC50 of 0.6 μM against BCRP efflux transporter. Synonyms: (S)-ML753286; (3S,6S,12aS)-6-isobutyl-9-methoxy-3-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione; Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 2,3,6,7,12,12a-hexahydro-9-methoxy-3-methyl-6-(2-methylpropyl)-, (3S,6S,12aS)-. Grade: ≥98%. CAS No. 1699720-85-8. Molecular formula: C20H25N3O3. Mole weight: 355.43.
b-Cryptoxanthin palmitate
b-Cryptoxanthin palmitate. Group: Biochemicals. Alternative Names: (3R)-3-Palmitoxy-b,b-carotene. Grades: Highly Purified. Pack Sizes: 1mg, 2mg, 5mg. US Biological Life Sciences.
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BCTC
BCTC. Group: Biochemicals. Alternative Names: 4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide. Grades: Highly Purified. CAS No. 393514-24-4. Pack Sizes: 5mg. Molecular Formula: C20H25ClN4O, Molecular Weight: 372.89. US Biological Life Sciences.
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BCTC
BCTC is an orally active current inhibitor of vanilloid receptor type 1 (VR1). BCTC is a transient receptor potential cation channel subfamily M member 8 (TRPM8) and transient receptor potential vanilloid 1 (TRPV1) antagonist. BCTC is an insulin sensitizer and secretor. BCTC has anticancer and analgesic effects[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 393514-24-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19960.
BCTC
BCTC is a TRPA1 and TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 with IC50 values of 35 and 6 nM, respectively. Uses: Orally effective vanilloid receptor 1. Synonyms: 4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide; N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)piperazine-1-carboxamide. Grade: ≥98%. CAS No. 393514-24-4. Molecular formula: C20H25ClN4O. Mole weight: 372.89.
BCX 1470
In vitro BCX 1470 inhibits the esterolytic and hemolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM) which is the complement enzymes. BCX 1470 may used for the treatment of complement activation during cardiopulmonary bypass surgery. Synonyms: (2-carbamimidoyl-1-benzothiophen-6-yl) thiophene-2-carboxylate; 2-amidino-6-(2-thiophene carboxy)benzothiophene methanesulfonate; BCX 1470; BCX1470; BCX-1470. Grade: 95%. CAS No. 217099-43-9. Molecular formula: C14H10N2O2S2. Mole weight: 302.37.
BCX 1470 methanesulfonate
BCX 1470 methanesulfonate is methanesulfonate salt form of BCX 1470. In vitro BCX 1470 inhibits the esterolytic and hemolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM) which is the complement enzymes. BCX 1470 may used for the treatment of c. Synonyms: BCX 1470 methanesulfonate; BCX-1470 methanesulfonate; BCX1470 methanesulfonate; (2-carbamimidoyl-1-benzothiophen-6-yl) thiophene-2-carboxylate; methanesulfonic acidBCX 1470 (methanesulfonate)217099-44-0BCX 1470(methanesulfonate)CHEMBL2203422C14H10N2O2S2.CH4O3S3166AH2-(Aminoiminomethyl)benzo[b]thiophen-6-yl ester 2-thiophenecarb. Grade: 95%. CAS No. 217099-44-0. Molecular formula: C14H10N2O2S2.CH4O3S. Mole weight: 398.47.
BCX 1470 methanesulfonate
BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D (IC50=96 nM) and C1s (IC50=1.6 nM), 3.4- and 200-fold better, respectively, than that of trypsin. Uses: Scientific research. Category: Signaling pathways. CAS No. 217099-44-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50875.
BCX4430 freebase
BCX4430, a novel synthetic adenosine analogue, inhibits infection of distinct filoviruses in human cells. Interfering with the replication process is a well-established antiviral strategy that has been successfully exploited in developing such life-saving drugs as the nucleoside inhibitors of HIV and acyclovir for herpes simplex complex. BCX4430 may be suitable for administration by intravenous (IV), intramuscular (IM), and oral (PO) routes. Uses: Antiviral agents. Synonyms: BCX-4430 freebase; BCX 4430 freebase; BCX4430 freebase; Immucillin-A; Immucillin A. Grade: >98%. CAS No. 249503-25-1. Molecular formula: C11H15N5O3. Mole weight: 265.27.
BCX 4430 hydrochloride
BCX4430, a novel synthetic adenosine analogue, inhibits infection of distinct filoviruses in human cells. Interfering with the replication process is a well-established antiviral strategy that has been successfully exploited in developing such life-saving drugs as the nucleoside inhibitors of HIV and acyclovir for herpes simplex complex. BCX4430 may be suitable for administration by intravenous (IV), intramuscular (IM), and oral (PO) routes. Synonyms: BCX-4430; BCX 4430; BCX4430; Immucillin-A hydrochloride; Immucillin A hydrochloride. Grade: >98%. CAS No. 222631-44-9. Molecular formula: C11H16ClN5O3. Mole weight: 301.73.
b-Cyano-L-alanine 98+%
b-Cyano-L-alanine 98+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
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b-Cyclodextrin polymer crosslinked with epichlorohydrin
b-Cyclodextrin polymer crosslinked with epichlorohydrin is an immensely multifaceted biomedical material, denoting an intriguing compound for drug delivery and encapsulation purposes. Emanating a profound affinity towards hydrophobic drugs, this polymer manifests its aptitude in orchestrating the restrained discharge of therapeutic drugs, including anti-inflammatory substances and anticancer compounds. Synonyms: Poly-beta-cyclodextrin (Cross-linked by Epichlorohydrin).
b-Cyclogeraniol
b-Cyclogeraniol. Group: Biochemicals. Alternative Names: 2,6,6-Trimethyl-1-cyclohexene-1-methanol; Cyclogeranyl alcohol. Grades: Highly Purified. CAS No. 472-20-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C10H18O. US Biological Life Sciences.
Bd 1008 dihydrobromide. Alternative Names: N-[2-(3,4-Dichlorophenyl)ethyl]-N-methyl-1-pyrrolidineethanamine Dihydrobromide. CAS No. 138356-09-9. Purity: 96%. Product ID: ACM138356099. Molecular formula: C15H24Br2Cl2N2. Mole weight: 463.08. IUPAC Name: 2-(3,4-dichlorophenyl)-N-methyl-N-(2-pyrrolidin-1-ylethyl)ethanamine;dihydrobromide. Alfa Chemistry - ISO 9001:32057 Certified.
BD 1008 dihydrobromide
BD 1008 dihydrobromide is a potent and selective σ receptor antagonist displaying 4-fold selectivity for σ1 over σ2. BD-1008 attenuates the toxicity and stimulant effects of cocaine, and can be used as the treatment of cocaine overdose and neuropathic pain after chemotherapy. Synonyms: BD1008 dihydrobromide; BD-1008 dihydrobromide; N-[2-(3,4-Dichlorophenyl)ethyl]-N-methyl-2-(1-pyrrolidinyl)ethylamine dihydrobromide; 1-Pyrrolidineethanamine, N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-, hydrobromide (1:2); 1-Pyrrolidineethanamine, N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-, dihydrobromide. Grade: ≥95%. CAS No. 138356-09-9. Molecular formula: C15H22Cl2N2.2HBr. Mole weight: 463.08.
BD 1008 dihydrobromide
BD 1008 dihydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 138356-09-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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BD 1047
BD 1047 is a selective antagonist of sigma-1 receptor. BD 1047 exhibits antipsychotic activity in animal models predictive of efficacy in schizophrenia. Synonyms: N1-[2-(3,4-Dichlorophenyl)ethyl]-N1,N2,N2-trimethyl-1,2-ethanediamine; [2-(3,4-Dichlorophenyl)ethyl][2-(dimethylamino)ethyl]methylamine; BD-1047; BD1047. Grade: >99 %. CAS No. 138356-20-4. Molecular formula: C13H20Cl2N2. Mole weight: 275.22.
BD 1047 dihydrobromide
BD 1047 dihydrobromide. CAS No. 138356-21-5. Product ID: ACM138356215. Mole weight: 437.04. Alfa Chemistry - ISO 9001:32057 Certified.
BD 1047 dihydrobromide
The dihydrobromide salt form of BD-1047, a selective σ1 receptor antagonist, has been found to have antipsychotic effect and could be probably used against schizophrenia and neuropathic pain. Uses: Bd 1047 dihydrobromide is a selective antagonist of σ receptors. Synonyms: BD-1047 (dihydrobromide); BD-1047 dihydrobromide; N-[2-(3,4-Dichlorophenyl)ethyl]-N-methyl-2-(dimethylamino)ethylamine dihydrobromide. Grade: 98%. CAS No. 138356-21-5. Molecular formula: C13H22Br2Cl2N2. Mole weight: 437.04.
BD 1047 dihydrobromide
BD 1047 dihydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 138356-21-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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BD-1047 dihydrobromide
BD-1047 dihydrobromide is a selective functional antagonist of sigma receptors. BD-1047 dihydrobromide attenuates Apomorphine (HY-12723)-induced climbing and Phencyclidine-induced head twitches[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 138356-21-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-16996A.
BD 1063
BD 1063. Group: Biochemicals. Alternative Names: 1-[2-(3,4-Dichlorophenyl)ethyl]-4-methylpiperazine. Grades: Highly Purified. CAS No. 150208-28-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C13H18Cl2N2. US Biological Life Sciences.
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BD 1063-d8 Dihydrochloride
Labeled BD 1063. The novel ? receptor ligands. Group: Biochemicals. Alternative Names: 1-[2-(3,4-Dichlorophenyl)ethyl]-4-methylpiperazine. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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BD-1063 dihydrochloride
BD-1063 dihydrochloride is a selective σ-1 receptor antagonist with inhibitory activity against TRPC5 and TRPM3. BD-1063 dihydrochloride exerts anti-hyperalgesic and anti-allodynic effects by inhibiting sustained calcium influx mediated by TRPC5 and TRPM3, and reverses the effects of Carrageenan (HY-125474). BD-1063 dihydrochloride also significantly reduces excessive ethanol self-administration behavior. BD-1063 dihydrochloride is widely used in studies on the mechanisms underlying neuropathic pain, inflammatory hyperalgesia, and alcohol abuse and dependence[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 206996-13-6. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18101A.
BD1063 dihydrochloride
BD1063 dihydrochloride is a potent and selective antagonist of sigma 1 receptor (Ki = 9.15 nM) with 50-fold more selective over sigma-2 (Ki = 449 nM) and >100-fold more selective over 9 other tested neurotransmitter receptors. Synonyms: BD1063 dihydrochloride; BD-1063 dihydrochloride; 1-(3,4-dichlorophenethyl)-4-methylpiperazine dihydrochloride; Piperazine, 1-[2-(3,4-dichlorophenyl)ethyl]-4-methyl-, dihydrochloride. Grade: ≥98%. CAS No. 206996-13-6. Molecular formula: C13H20Cl4N2. Mole weight: 346.12.
BD 1063 Dihydrochloride
The novel ? receptor ligands. Group: Biochemicals. Alternative Names: 1-[2-(3,4-Dichlorophenyl)ethyl]-4-methylpiperazine Dihydrochloride. Grades: Highly Purified. CAS No. 206996-13-6. Pack Sizes: 10mg. US Biological Life Sciences.
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BD140 [for Albumin binding assay]
Alfa Chemistry offers high-purity BD140 [for Albumin binding assay] products for various research purposes. Please contact us by email if you do not find the specification you are looking for on this page. Alternative Names: 4,4-Difluoro-1-methyl-3-(4-propoxystyryl)-4-bora-3a,4a-diaza-s-indacene. CAS No. 1201643-08-4. Molecular formula: C21H21BF2N2O. Mole weight: 366.22. Purity: >98.0%(GC).
BD140 [for Albumin binding assay]
BD140 [for Albumin binding assay]. Synonyms: 2,2-difluoro-6-methyl-4-[(E)-2-(4-propoxyphenyl)ethenyl]-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaene; 4,4-Difluoro-1-methyl-3-(4-propoxystyryl)-4-bora-3a,4a-diaza-s-indacene; (E)-5,5-Difluoro-1-methyl-3-(4-propoxystyryl)-5H-5l4,6l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinine. Grade: >98.0% by GC. CAS No. 1201643-08-4. Molecular formula: C21H21BF2N2O. Mole weight: 366.22.
b-D-(2-Acetamido-2-deoxy-D-glucopyranosyl)-2-acetamido-2-deoxy-b-D-thioglucopyranoside is a highly intricate and multifaceted compound, assuming a pivotal role in investigating the intricate interplay between proteins and carbohydrates. It facilitates the meticulous examination of lectin-carbohydrate associations, glycosylation procedures and the formulation of researchs targeting multifarious ailments such as cancer and viral infections. Synonyms: Thiodi-N-acetylglucoside. Molecular formula: C16H28N2O10S. Mole weight: 440.47.
BD750
BD750 is a dual inhibitor of JAK3 and STAT5 used as an immunosuppressant. BD750 inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation, preventing graft rejection and treating autoimmune diseases. Synonyms: BD 750; BD-750; 2-(Benzo[d]thiazol-2-yl)-4,5,6,7-tetrahydro-2H-indazol-3-ol. CAS No. 892686-59-8. Molecular formula: C14H13N3OS. Mole weight: 271.34.
BD750
BD750, an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation, with IC50 values of 1.5 μM and 1.1 μM in mouse and human T cells, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 892686-59-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131140.
BD-9136
BD-9136 is a potent and highly selective BRD4 PROTAC depressant. BD-9136 has low-nanomolar degradation potencies against BRD4 , and its degradation selectivity for BRD4 is 1000 times that of BRD2 and BRD3 proteins. BD-9136 has antitumor activity[1].(Pink: Desmethyl-QCA276 (HY-44103); Black: 3-(2-(4-Methylpiperazin-1-yl)ethyl)azetidin-3-ol; Blue: Thalidomide-4-OH (HY-103596)). Uses: Scientific research. Category: Signaling pathways. CAS No. 3037514-38-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-149878.
BDA-366
BDA-366 is a small-molecule antagonist of Bcl2-BH4 domain with high affinity and selectivity for Bcl2-BH4. BDA-366 induces apoptosis in multiple myeloma cells via Bcl2 conformational change. Synonyms: BDA-366; BDA 366; BDA366; 1-[[(2S)-3-(diethylamino)-2-hydroxypropyl]amino]-4-[[(2S)-oxiran-2-yl]methylamino]anthracene-9,10-dione. Grade: >98%. CAS No. 1909226-00-1. Molecular formula: C24H29N3O4. Mole weight: 423.513.
b-D-Allopyranose
b-D-Allopyranose, an essential monosaccharide, finds extensive utility within the biomedicine sector. Its status as a natural product adds to its credibility. Primarily regarded as a precursor, this compound plays a crucial role in synthesizing diverse drugs and compounds. These substances, in turn, cater to combating diabetes, cancer, and viral infections. Remarkably, the distinctiveness of b-D-Allopyranose's structure is attributed to its extraordinary therapeutic benefits. By enhancing glucose metabolism, restraining tumor growth, and countering viral replication, researchers and pharmaceutical enterprises find immense value in this compound. Synonyms: beta-D-allose; beta-D-allopyranose; (2R,3R,4R,5S,6R)-6-(Hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol. CAS No. 7283-9-2. Molecular formula: C6H12O6. Mole weight: 180.16.