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| Product | Description | |
|---|---|---|
| CLZ-8 | CLZ-8 (Compound 8) is an orally active Mcl-1-PUMA interface inhibitor, with a Ki of 0.3 μM. CLZ-8 exhibits dual activity on reduce PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis in cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 678158-55-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122627. |  |
| CM037 | CM037 is a highly selective and competitive ALDH1A1 inhibitor (IC50=4.6 μM). CM037 blocks the catalytic activity of ALDH1A1, thereby inhibiting the activation of the downstream HIF-1α/VEGF pathway. CM037 is mainly used to study the ALDH1A1-mediated regulation of cancer stem cells (CSCs) and angiogenesis, especially in breast cancer, showing the potential to inhibit tumor angiogenesis and stem cell characteristics[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: A37. CAS No. 896795-60-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-110294. | |
| CM1 | CM1 is an orally active iron chelator with high selectivity for iron(III). It can penetrate hepatocytes. CM1 is potentially used for patients with thalassaemia related iron overload and exhibits an inhibitory effect on the growth of Plasmodium falciparum (malaria parrasite; IC50 value 35 μM). Uses: The treatment of thalassaemia related iron overload. Synonyms: CM-1; CM 1; 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one. Grade: 99%. CAS No. 1643659-63-5. Molecular formula: C14H22N2O3. Mole weight: 266.34. |  |
| CM 10 | CM 10 is an inhibitor of aldehyde dehydrogenase 1A (ALDH1A) inhibitor. It can induce a necroptotic phenotype and preferentially deplete CD133+ ovarian cancer stem cells in vitro. Synonyms: 2-(2-Propen-1-yl)-6-[[(1-propyl-1H-benzimidazol-2-yl)amino]methyl]phenol. Grade: ≥98% by HPLC. CAS No. 692269-09-3. Molecular formula: C20H23N3O. Mole weight: 321.42. | |
| CM-1758 | CM-1758 is a histone deacetylase (HDAC) inhibitor. CM-1758 inhibits tumor growth in vivo. CM-1758 induces acetylation of non-histone proteins in acute myeloid leukemia cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2256079-39-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161149. | |
| CM-24 | CM-24 is a humanized antibody expressed in CHO cells, targeting CEACAM1/CD66a. The predicted molecular weight (MW) of CM-24 is 145 kDa. The isotype control for CM-24 can refer to Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: MK-6018. CAS No. 1783801-93-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990569. | |
| CM-272 | CM-272 is a first-in-class, potent, selective, substrate-competitive and reversible dual G9a/DNA methyltransferases (DNMTs) inhibitor with antitumor activities. CM-272 inhibits G9a, DNMT1, DNMT3A, DNMT3B and GLP with IC50s of 8 nM, 382 nM, 85 nM, 1200 nM and 2 nM, respectively. CM-272 inhibits cell proliferation and promotes apoptosis, inducing IFN-stimulated genes and immunogenic cell death[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1846570-31-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101925. | |
| CM-272 | CM-272 is a first-in-class reversible and substrate-competitive dual inhibitor of G9a (GLP) and DNMTs. CM-272 inhibits cell proliferation and promotes apoptosis, inducing interferon-stimulated genes and immunogenic cell death in models of haematological neoplasia. Synonyms: CM 272; CM272. CAS No. 1846570-31-7. Molecular formula: C28H38N4O3. Mole weight: 478.63. | |
| CM-3 | CM-3 is a synthetic construct with antibacterial activity. | |
| CM-352 | CM-352 has been found to be a MMP inhibitor that could probably be used as an antihemorrhagic agent with little influence in normal hemostatic function. Synonyms: CM352; CM 352; CM-352; (R)-N-hydroxy-2-((4-(4-(methylcarbamoyl)phenoxy)phenyl)sulfonyl)-8-azaspiro[4.5]decane-2-carboxamide. Grade: 98%. CAS No. 1542205-83-3. Molecular formula: C24H29N3O6S. Mole weight: 487.57. | |
| CM398 | CM398 has preferential affinity for sigma-2 receptor compared with sigma-1 receptor and at least four other neurotransmitter receptors sites, including the norepinephrine transporter. Synonyms: 1-(4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1h)-yl)butyl)-3-methyl-1h-benzo[d]imidazol-2(3h)-one. Grade: 98%. CAS No. 1121931-70-1. Molecular formula: C23H29N3O3. Mole weight: 395.49. | |
| CM398 | CM398 is a highly selective, orally active Sigma-2 receptor ligand with a Ki value of 0.43 nM. CM398 ameliorates age-related macular degeneration. CM398 exerts analgesic effects on visceral pain, inflammatory pain and neuropathic pain. CM398 can be used in research related to age-related macular degeneration, neuropathic pain and inflammatory pain[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1121931-70-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145628. | |
| CM-579 trihydrochloride | CM-579 trihydrochloride is a first-in-class reversible and dual inhibitor of G9a and DNMT, with IC50s of 16 nM and 32 nM, respectively. It has potent in vitro cellular activity in a wide range of cancer cells. Synonyms: 6-Methoxy-2-(5-methyl-2-furyl)-N-[(1-methyl-4-piperidinyl)methyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinolinamine trihydrochloride; 4-Quinolinamine, 6-methoxy-2-(5-methyl-2-furanyl)-N-[(1-methyl-4-piperidinyl)methyl]-7-[3-(1-pyrrolidinyl)propoxy]-, hydrochloride (1:3). Grade: ≥95%. Molecular formula: C29H43Cl3N4O3. Mole weight: 602.04. | |
| CMA | CMA is a murine-selective agonist of STING. It triggers type I IFN response in murine macrophages, without effect on human STING signaling. Synonyms: 9-Oxo-10(9H)-acridineacetic acid. Grade: ≥98% by HPLC. CAS No. 38609-97-1. Molecular formula: C15H11NO3. Mole weight: 253.25. | |
| CMB-087229 | CMB-087229 is a mutant superoxide dismutase 1 (SOD1) protein aggregation inhibitor with IC50 of 67 nM, which can be used in the research of amyotrophic lateral sclerosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1227692-67-2. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg. Product ID: HY-148901. | |
| CMC2.24 | CMC2.24 is an orally active tricarbonylmethane agent. It is effective against pancreatic tumor in mice by inhibiting Ras activation and its downstream effector ERK1/2 pathway. CMC2.24 is also a potent inhibitor of zinc-dependent MMPs with IC50s ranging from 2.0-69 μM. Synonyms: TRB-N0224. Grade: 96%. CAS No. 1255639-43-0. Molecular formula: C26H21NO5. Mole weight: 427.45. | |
| CMC-Na | CMC-Na (Sodium carboxymethyl cellulose) is one of the important modified cellulose, a water-soluble cellulose, which is widely used in many application of food, pharmaceuticals, detergent, paper coating, dispersing agent, and others. Its addition possibly increases the hydrogenation and dehydrogenation features of Magnesium. Group: Inhibitors. Alternative Names: Sodium carboxymethyl cellulose. CAS No. 9004-32-4. Pack Sizes: 5g. Product ID: S6703. Smiles: CC(=O)O.C(C(C(C(C(C=O)O)O)O)O)O.[Na]. |  United States; Europe |
| CMC-Na | CMC-Na (Sodium carboxymethyl cellulose) is one of the important modified cellulose, a water-soluble cellulose, which is widely used in many application of food, pharmaceuticals, detergent, paper coating, dispersing agent, and others. CAS No. 9004-32-4. Product ID: PE-0150. Category: Binder Excipients. Product Keywords: Pharmaceutical Excipients; Solid Dosage Form; Binder Excipients; CMC-Na; PE-0150; 9004-32-4; 9004-32-4. Purity: 0.9972. Synonym(s): Sodium carboxymethyl cellulose. Storage: 3 years -20°C powder. |  |
| CMD178 | CMD178 is a lead peptide that can sustainably reduce the expression of Foxp3 and STAT5 induced by IL-2/ S IL-2Rα signal. CMD178 is also a STAT5 inhibitor and inhibits the development of Treg cells. Synonyms: H-Arg-Phe-Lys-Phe-Tyr-OBn; L-arginyl-L-phenylalanyl-L-lysyl-L-phenylalanyl-L-tyrosine benzyl ester; RFKFY-OBn; CMD 178; CMD-178. Grade: ≥98%. CAS No. 2703745-80-4. Molecular formula: C46H59N9O7. Mole weight: 850.03. | |
| CMD178 TFA | CMD178 (TFA) is a peptide, which consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/sIL-2Rα signaling. Synonyms: H-Arg-Phe-Lys-Phe-Tyr-OBn.TFA; L-arginyl-L-phenylalanyl-L-lysyl-L-phenylalanyl-L-tyrosine benzyl ester trifluoroacetic acid; RFKFY-OBn.TFA; CMD 178 TFA; CMD-178 TFA. Grade: 98%. CAS No. 2703745-81-5. Molecular formula: C46H59N9O7.C2HF3O2. Mole weight: 964.05. | |
| CM-Dextran sodium salt | CM-Dextran sodium salt. CAS No. 39422-83-8. |  |
| c-Met-IN-1 | c-Met-IN-1, a potent and selective c-Met inhibitor (IC50 = 1.1 nM), has antitumor activity. Synonyms: N-[3-Fluoro-4-[6-methoxy-7-[3-(4-methylpiperazino)propoxy]quinoline-4-yloxy]phenyl]-1-(2-methoxyphenyl)-1H-imidazole-4-carboxamide; 1H-Imidazole-4-carboxamide, N-[3-fluoro-4-[[6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-4-quinolinyl]oxy]phenyl]-1-(2-methoxyphenyl)-. Grade: ≥95%. CAS No. 2084836-84-8. Molecular formula: C35H37FN6O5. Mole weight: 640.70. | |
| c-Met-IN-2 | c-Met-IN-2, a potent, selective and orally available c-Met inhibitor (IC50 = 0.6 nM), has antitumor activity. Synonyms: 2-[4-(1-{1-[7-Fluoro-3-(1-methyl-1H-pyrazol-4-yl)-6-quinolinyl]ethyl}-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl]ethanol; 1H-Pyrazole-1-ethanol, 4-[1-[1-[7-fluoro-3-(1-methyl-1H-pyrazol-4-yl)-6-quinolinyl]ethyl]-1H-1,2,3-triazolo[4,5-b]pyrazin-6-yl]-. Grade: ≥95%. CAS No. 1635406-73-3. Molecular formula: C24H21FN10O. Mole weight: 484.49. | |
| c-Met inhibitor 1 | c-Met inhibitor 1 is an inhibitor of the c-Met receptor signaling pathway useful for the treatment of cancer including gastric, glioblastoma, and pancreatic cancer. Synonyms: c-Met inhibitor 1; c Met inhibitor 1. Grade: >98%. CAS No. 1357072-61-7. Molecular formula: C17H14N8S. Mole weight: 362.41. | |
| CMF019 | CMF019 is an orally active, potent and small molecule agonist at Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ with pKi values of 8.58, 8.49 and 8.71 for human, rat, and mouse, respectively. CMF019 mimics the beneficial cardiovascular actions of apelin in rodents[1]. Apelin receptor (APJ) is a G protein-coupled receptor (GPCR) activated by the endogenous peptide apelin. CMF019 is promising for research of chronic diseases, such as, pulmonary arterial hypertension[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1586787-08-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103080. | |
| CMG-101 | CMG-101 is a novel selective inhibitor of mTORC1/2. Studies suggest that CMG-101 would overcome the drug resistance of mTORC1 inhibitor through the activation of signal transduction pathways via mTORC2. CMG-101 is promisingly to be a antitumor drug. Uses: Potential antitumor drug. Synonyms: CMG101; CMG 101. | |
| CM-H2DCFDA | CM-H2DCFDA is a derivative of H2DCFDA (HY-D0940). CM-H2DCFDA can be used to determine cellular oxidant levels (Ex/Em: 495/530 nm). CM-H2DCFDA is light-sensitive[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 850013-49-9. Pack Sizes: 50 μg. Product ID: HY-D1713. | |
| CMHPG | CMHPG. |  |
| CMI-392 | CMI-392 is a dual antagonist of 5-lipoxygenese (IC50= 100 nM) and platelet-activating factor (PAF) receptor (IC50= 10 nM). Uses: Lipoxygenase inhibitors. Synonyms: 3-[[2-[2-(4-chlorophenyl)sulfanylethoxy]-3-methoxy-5-[(2S,5S)-5-(3,4,5-trimethoxyphenyl)oxolan-2-yl]phenyl]methyl]-1-hydroxy-1-methylurea; 2-(3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N-hydroxyureidyl)methylphenyl)-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran; CMI 392; CMI-392. CAS No. 205654-37-1. Molecular formula: C31H37ClN2O8S. Mole weight: 633.15. | |
| CMI-977 | CMI-977, an oxolan compound, has been found to be a 5-Lipoxygenases inhibitor and was once studied as an antiasthmatic agent. Synonyms: CMI-977; CMI 977; CMI977; LPD-977; LPD 977; LPD977; MLN-977; MLN977; MLN 977; 1-[4-[(2S,5S)-5-[(4-fluorophenoxy)methyl]oxolan-2-yl]but-3-ynyl]-1-hydroxyurea. Grade: 98%. CAS No. 175212-04-1. Molecular formula: C16H19FN2O4. Mole weight: 322.34. | |
| CMIT/MIT (14.5% in water) | CMIT/MIT is a CMIT and MIT mixture. CMIT and MIT are powerful synthetic biocidal substances. CMIT and MIT are used as preservatives in various cosmetics and industrial products. CMIT and MIT are present in many water-soluble consumer products, such as shampoos, toothpastes. CMIT/MIT (3:1 mixture of CMIT and MIT) produces mitochondrial ROS via inhibiting mitochondrial complex I and II. CMIT/MIT (in 3:1 ratio) induces neurotoxicity through the upregulation of the MAPKs signaling pathways. CMIT/MIT can be used in the research of respiratory diseases and neuroblastoma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CMI/MI. CAS No. 55965-84-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 g; 500 g; 1 k g. Product ID: HY-W017982. | |
| CMK | CMK is a RSK2 kinase inhibitor. Its IC50 value for Cdc5(L158G) is 36 nM. It is used in the preparation of serine/threonine kinase inhibitors. Uses: Cmk is used in the preparation of serine/threonine kinase inhibitors. Synonyms: 1-(4-Amino-7-(3-hydroxypropyl)-5-(p-tolyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl)-2-chloroethanone. Grade: 95%. CAS No. 821794-90-5. Molecular formula: C18H19ClN4O2. Mole weight: 358.82. | |
| CMK | CMK is a RSK2 kinase inhibitor which exhibits similar potency but less chemical stability compared with FMK. Uses: Scientific research. Category: Signaling pathways. CAS No. 821794-90-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-52101. | |
| CMK-3 | CMK-3. CAS No. 7440-44-0. Product ID: ACM7440440-216. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| CMK-8 | CMK-8. CAS No. 7440-44-0. Product ID: ACM7440440-161. Alfa Chemistry - ISO 9001:32057 Certified. | |
| CMKLR1 antagonist 1 | CMKLR1 antagonist 1 (compound S-26d) is a potent and orally active chemokine-like receptor 1 (CMKLR1) antagonist, with a pIC50 value of 7.44 in hCMKLR1-transfected CHO cells. CMKLR1 antagonist 1 can be used for psoriasis and metabolic diseases research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3033101-08-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156460. | |
| CMLD012072 | CMLD012072, an amidino-rocaglates, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor with strong antitumor activity. It can induce RNA to clamp eIF4A1 and eIF4A2. Synonyms: Methyl (3aR,4R,5S,5aR,10bR)-2-cyclopropyl-3a-hydroxy-8,10-dimethoxy-5a-(4-methoxyphenyl)-5-phenyl-3a,4,5,5a-tetrahydro-1H-[1]benzofuro[3',2':1,5]cyclopenta[1,2-d]imidazole-4-carboxylate; 1H-Benzofuro[3',2':1,5]cyclopent[1,2-d]imidazole-4-carboxylic acid, 2-cyclopropyl-3a,4,5,5a-tetrahydro-3a-hydroxy-8,10-dimethoxy-5a-(4-methoxyphenyl)-5-phenyl-, methyl ester, (3aR,4R,5S,5aR,10bR)-. Grade: ≥95%. CAS No. 2368900-33-6. Molecular formula: C32H32N2O7. Mole weight: 556.61. | |
| CMLD012073 | CMLD012073, an amidino-rocaglates and a potent eukaryotic initiation factor 4A (eIF4A) inhibitor, inhibits NIH/3T3 cells growth with an IC50 of 10 nM. It inhibits eukaryotic translation initiation by modifying the behavior of the RNA helicase (eIF4A). Synonyms: 3H-Benzofuro[3',2':1,5]cyclopent[1,2-d]imidazole-4-carboxylic acid, 3a,4,5,5a-tetrahydro-3a-hydroxy-8,10-dimethoxy-5a-(4-methoxyphenyl)-2-methyl-5-phenyl-, methyl ester, (3aR,4R,5S,5aR,10bR)-; Methyl (3aR,4R,5S,5aR,10bR)-3a-hydroxy-8,10-dimethoxy-5a-(4-methoxyphenyl)-2-methyl-5-phenyl-3a,4,5,5a-tetrahydro-1H-[1]benzofuro[3',2':1,5]cyclopenta[1,2-d]imidazole-4-carboxylate. Grade: ≥97%. CAS No. 2368900-32-5. Molecular formula: C30H30N2O7. Mole weight: 530.57. | |
| CML-d2 | CML-d2. Synonyms: N-epsilon-carboxy[D2]methyl-L-Lysine; H-L-Lys(Cm)-OH-d2; H-Lys(Cm)-OH-d2; (S)-2-amino-6-(carboxy[D2]methylamino)hexanoic acid. Molecular formula: C8H14D2N2O4. Mole weight: 206.24. | |
| CMLD-2 | CMLD-2 is an inhibitor of HuR-ARE interaction. CMLD-2 induces apoptosis and exhibits antitumor activity in different cancer cells as colon, pancreatic, thyroid and lung cancer cell lines. Synonyms: 5,7-dimethoxy-8-(1-(4-methoxyphenyl)-3-oxo-3-(pyrrolidin-1-yl)propyl)-4-phenyl-2H-chromen-2-one. Grade: 98%. CAS No. 958843-91-9. Molecular formula: C31H31NO6. Mole weight: 513.58. | |
| CMLD-2 | CMLD-2, an inhibitor of HuR-ARE interaction, competitively binds HuR protein disrupting its interaction with adenine-uridine rich elements (ARE)-containing mRNAs (Ki=350 nM). CMLD-2 induces apoptosis exhibits antitumor activity in different cancer cells as colon, pancreatic, thyroid and lung cancer cell lines. Hu antigen R (HuR) is an RNA binding protein, can regulate target mRNAs stability and translation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 958843-91-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-124828. | |
| Cm-p1 | Cm-p1 was found in marine snail Cenchritis muricatus. This peptide demonstrated the capacity to prevent the development of yeasts and filamentous fungi. Otherwise, Cm-p1 displayed no toxic effects against mammalian cells. | |
| CMP5 | CMP5 is a potent and selective PRMT5 inhibitor suppressing EBV-driven B-lymphocyte transformation while leaving normal B cells unaffected. Inhibition of PRMT5 effetively blocked recall T cell responses, reduced inflammation in delayed-type hypersensitivity and clinical disease in experimental autoimmune encephalomyelitis mouse models. Synonyms: CMP5; CMP 5; CMP-5; 1-(9-ethylcarbazol-3-yl)-N-(pyridin-2-ylmethyl)methanamine Hydrochloride; AKOS032401780. Grade: 99%. CAS No. 1030021-40-9. Molecular formula: C20H22N3.HCl. Mole weight: 351.87. | |
| CMP-5 | CMP5 is a potent, selective and specific inhibitor of PRMT5, but has no activity against PRMT1, PRMT4 and PRMT7 enzymes. CMP5 selectively blocks S2Me-H4R3 by inhibiting the activity of PRMT5 methyltransferase on histone preparations. It prevents epstein-barr virus (EBV)-driven B-lymphocyte transformation, but does not affect normal B cells. Synonyms: 1-(9-ethyl-9H-carbazol-3-yl)-N-(pyridin-2-ylmethyl)methanamine; PRMT5-IN-5; N-[(9-ethyl-9H-carbazol-3-yl)methyl]-N-(2-pyridinylmethyl)amine; 9H-Carbazole-3-methanamine, 9-ethyl-N-(2-pyridinylmethyl)-. Grade: ≥98%. CAS No. 880813-42-3. Molecular formula: C21H21N3. Mole weight: 315.41. | |
| CMP-5 2HCl | CMP-5 2HCl is a repellent. The EC100 of CMP-5 2HCl in vitro against H. contortus is 5 μM. Synonyms: 9H-Carbazole-3-methanamine, 9-ethyl-N-(2-pyridinylmethyl)-,hydrochloride (1:2). Grade: >98.0%. CAS No. 2309409-79-6. Molecular formula: C21H23Cl2N3. Mole weight: 388.34. | |
| CMP8 | CMP8 is a selective ligand for the estrogen receptor, which can bind to the ligand binding domain of the estrogen receptor. The IC50 values of CMP8 for mutant MGERα, MGRERα and wild-type hERα and hERβ are 29 nM, 41 nM, 1100 nM and 2200 nM, respectively. Grade: 98%. CAS No. 851107-28-3. Molecular formula: C33H34ClNO3. Mole weight: 528.1. | |
| CMP-9-fluoresceinyl-NeuAc | CMP-9-fluoresceinyl-NeuAc, is shown to be a suitable donor substrate for sialyltransferase, which belongs to glycosyltransferase family 29. Synonyms: N-Acetyl-9-deoxy-9-[[[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]thioxomethyl]amino]-2-(hydrogen 5'-cytidylate) β-Neuraminic Acid; 5-(Acetylamino)-3,5,9-trideoxy-9-[[[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]thioxomethyl]amino]-D-glycero-β-D-galacto-2-Nonulopyranosonic Acid 2-(Hydrogen 5'-cytidylate); Spiro[isobenzofuran-1(3H),9'-[9H]xanthene] D-glycero-β-D-galacto-2-nonulopyranosonic acid Deriv. CAS No. 118720-35-7. Molecular formula: C41H43N6O20PS. Mole weight: 1002.85. | |
| CMP-9-O-acetyl-N-acetylneuraminic acid | CMP-9-O-acetyl-N-acetylneuraminic acid is an indispensable compound, having multifarious utilities in an array of maladies, ranging from influenza to viral infections and autoimmune disorders. The distinctive attributes it possesses render it an imperative constituent for investigating sialic acid metabolism and glycoconjugate. Synonyms: CMP-9-O-Ac-Neu5Ac. Molecular formula: C22H33N4O16P. Mole weight: 640.49. | |
| CMP-C9-Azido-Sialic Acid sodium | CMP-C9-Azido-Sialic Acid is a synthetic derivative belonging to the sialic acid family found in many types of glycoproteins and glycolipids. Grade: ≥85%. Molecular formula: C20H31N7NaO15P. Mole weight: 663.47. | |
| CMP-CP | CMP-CP is a non-hydrolytic analogue of CDP. It is commonly used as a starting structure in the synthesis of α/β hydrolysis-resistant tri- and polyphosphates. Synonyms: Cytidine- 5'- O- (α, β- methylene)diphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 101536-15-6. Molecular formula: C10H17N3O10P2 (free acid). Mole weight: 401.2 (free acid). | |
| CMPD1 | CMPD1 is a selective and non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation inhibitor with apparent Ki (Kiapp) of 330 nM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 41179-33-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-108643. | |
| CMPD-1 | CMPD-1, also called MK2a Inhibitor, inhibits tubulin polymerisation. It inhibit p38α-mediated MK2a phosphorylation (apparent Ki = 330 nM). Synonyms: CMPD1; CMPD-1; CMPD 1; IN1225; IN-1225; IN 1225; 4-[4-(2-fluorophenyl)phenyl]-N-(4-hydroxyphenyl)butanamide; MK2a Inhibitor; MAPKAPK2a Inhibitor; CMPD1; CHEMBL235658; 41179-33-3; IN1225; 4-(2' -Fluorobiphenyl-4-yl)-N-(4-hydroxyphenyl)-butyramide; Mitogen-activated protein kinase-activated protein kinase 2a Inhibitor; MK2a Inhibitor_x000D_; SCHEMBL169905. CAS No. 41179-33-3. Molecular formula: C22H20FNO2. Mole weight: 349.4. | |
| CMPD-1 | CMPD-1. Group: Biochemicals. Grades: Purified. CAS No. 41179-33-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| CMPD101 | CMPD101 is a selective GRK2/3 inhibitor with IC50 value is 54 nM for GRK3 and 32 nM for GRK2. It shows selectivity for GRK2/3 over GRK1/5. It can also reduce DAMGO-induced desensitization and internalization of μ-opioid receptors. Synonyms: CMPD101; CMPD 101; CMPD-101; Takeda101; Takeda-101; Takeda 101. 3-[[[4-Methyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]methyl]amino]-N-[[2-(trifluoromethyl)phenyl]methyl]benzamide. Grade: 98%. CAS No. 865608-11-3. Molecular formula: C24H21F3N6O. Mole weight: 466.46. | |
| CMPD101 | CMPD101 is a potent, highly selective and membrane-permeable small-molecule inhibitor of GRK2/3 with IC50 of 18 nM and 5.4 nM, respectively. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCα with IC50s of 3.1 μM , 2.3 μM, 1.4 μM and 8.1 μM, respectively. CMPD101 can be used for the study of heart failure[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 865608-11-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103045. | |
| CMPD-39 | CMPD-39 is a selective non-covalent inhibitor of the ubiquitin-specific protease USP30 (IC50=~20 nM), with high selectivity over other DUB family members (1-100 μM). CMPD-39 inhibits the deubiquitinating activity of USP30, enhances the ubiquitination of mitochondrial proteins TOMM20 and SYNJ2BP; thus, CMPD-39 promotes phosphoubuitin accumulation, thereby accelerating mitochondrial autophagy (mitophagy) and peroxisomal autophagy (pexophagy). CMPD-39 significantly restores impaired mitochondrial function in dopaminergic neurons derived from Parkinson's disease patients[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2242582-40-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141659. | |
| CMPDA | CMPDA is a positive allosteric modulator of AMPA receptors. Binds at the modulator binding pocket located at the interdimer interface and the clamshell hinges. Synonyms: CMPDA; 380607-77-2; N,N'-(1,4-Phenylenedi-2,1-ethanediyl)bis-2-propanesulfonamide; A36XX25K37; N-[2-[4-[2-(propan-2-ylsulfonylamino)ethyl]phenyl]ethyl]propane-2-sulfonamide; N,N'-(Benzene-1,4-Diyldiethane-2,1-Diyl)dipropane-2-Sulfonamide; 2-Propanesulfonamide, N,N'-(1,4-phenylenedi-2,1-ethanediyl)bis-; UNII-A36XX25K37; SCHEMBL6565144; BCP23929; AKOS024458123; CS-3632; HY-12508; MS-26117; E99011; Q27465085; N,N'-(2,2'-(1,4-phenylene)bis(ethane-2,1-diyl))dipropane-2-sulfonamide; RNN. Grade: >98%. CAS No. 380607-77-2. Molecular formula: C16H28N2O4S2. Mole weight: 376.53. | |
| CMPI [2-Chloro-1-methylpyridinium iodide] | CMPI [2-Chloro-1-methylpyridinium iodide]. Group: Biochemicals. Grades: Highly Purified. CAS No. 14338-32-0. Pack Sizes: 50g, 100g, 250g, 500g. US Biological Life Sciences. | Worldwide |
| CMP - lyophilized | CMP - lyophilized is an extensively employed biomolecule in the field of biomedical sciences due to its pivotal involvement in the intricate processes of DNA research and development and repair. Through serving as a fundamental constituent for nucleic acids, CMP assuming a critical role in facilitating cellular functions. Synonyms: Cytidine-5'-monophosphate, Disodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C9H14N3O8P (free acid). Mole weight: 323.20 (free acid). | |
| CMP-N-acetylneuraminate monooxygenase | This enzyme contains both a Rieske-type [2Fe-2S] cluster and a second iron site. The ferricytochrome b5 produced is reduced by NADH and cytochrome-b5 reductase (EC 1.6.2.2). The enzyme can be activated by Fe2+ or Fe3+. Group: Enzymes. Synonyms: CMP-N-acetylneuraminic acid hydroxylase; CMP-Neu5Ac hydroxylase; cytidine monophosphoacetylneuraminate monooxygenase; N-acetylneuraminic monooxygenase; cytidine-5'-monophosphate-N-acetylneuraminic acid hydroxylase. Enzyme Commission Number: EC 1.14.18.2. CAS No. 116036-67-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0964; CMP-N-acetylneuraminate monooxygenase; EC 1.14.18.2; 116036-67-0; CMP-N-acetylneuraminic acid hydroxylase; CMP-Neu5Ac hydroxylase; cytidine monophosphoacetylneuraminate monooxygenase; N-acetylneuraminic monooxygenase; cytidine-5'-monophosphate-N-acetylneuraminic acid hydroxylase. Cat No: EXWM-0964. |  |
| CMP-N-acetylneuraminic acid 9-sp-biotin | CMP-N-acetylneuraminic acid 9-sp-biotin. | |
| CMP-N-acetylneuraminic acid sodium salt | CMP-N-acetylneuraminic acid sodium salt, a fundamental compound employed in the field of biomedicine, exhibits immense utility in the management of diverse ailments associated with compromised sialic acid metabolism, including sialuria and sialic acid storage diseases. Synonyms: CMP-NANA; Cytidine 5-monophospho-b-D-N-acetylneuraminic acid sodium salt; CMP-Sialic Acid; CMP-Neu5Ac. CAS No. 3063-71-6. Molecular formula: C20H30N4NaO16P. Mole weight: 636.43. | |
| CMP-N-acylneuraminate phosphodiesterase | This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. Group: Enzymes. Synonyms: CMP-sialate hydrolase; CMP-sialic acid hydrolase; CMP-N-acylneuraminic acid hydrolase; cytidine monophosphosialic hydrolase; cytidine monophosphosialate hydrolase; cytidine monophosphate-N-acetylneuraminic acid hydrolase; CMP-N-acetylneuraminate hydrolase. Enzyme Commission Number: EC 3.1.4.40. CAS No. 55326-41-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3724; CMP-N-acylneuraminate phosphodiesterase; EC 3.1.4.40; 55326-41-5; CMP-sialate hydrolase; CMP-sialic acid hydrolase; CMP-N-acylneuraminic acid hydrolase; cytidine monophosphosialic hydrolase; cytidine monophosphosialate hydrolase; cytidine monophosphate-N-acetylneuraminic acid hydrolase; CMP-N-acetylneuraminate hydrolase. Cat No: EXWM-3724. | |
| CMP-Neu5,9Ac2 | CMP-Neu5,9Ac2 serves as a direct substrate of the NeuA O-acetyl esterase in vitro. Synonyms: β-Neuraminic acid, N-acetyl-, 9-acetate 2-(hydrogen 5'-cytidylate), ammonium salt (1:2). CAS No. 1045785-97-4. Molecular formula: C22H33N4O17P.2NH3. Mole weight: 690.55. | |
| CMP-Neu5Ac sodium salt | CMP-Neu5Ac sodium salt, a vital compound in the biomedical sector, is intricately involved in numerous biological processes, aiding in the synthesis of sialylated compounds. Notably, its indispensable role as a substrate for sialyltransferases facilitates the treatment of ailment manifestations characterized by aberrant sialylation. Afflicting individuals are plagued by a range of conditions, including cancer, neurological disorders, and autoimmune diseases, wherein CMP-Neu5Ac sodium salt assumes significance. Synonyms: CMP-NANA; Cytidine 5'-monophospho-b-D-N-acetylneuraminic acid sodium salt; CMP-N-acetylneuraminic acid sodium salt; CMP-Sialic Acid. Grade: 85%. CAS No. 1007117-62-5. Molecular formula: C20H30N4O16P·Na. Mole weight: 636.43. | |
| CMP-Neu5Az sodium | CMP-Neu5Az is a modified sialic acid nucleotide commonly used in glycosylation research, particularly for bioorthogonal labeling and metabolic engineering of sialic acids. Grade: ≥85%. Molecular formula: C20H28N7Na2O16P. Mole weight: 699.43. | |
| CMP-N-glycolylneuraminic acid | CMP-N-glycolylneuraminic acid is a fundamental compound extensively used in the biomedical field, serving as an indispensable precursor in the research and development of diverse sialic acid derivatives, which wield significant influence over a plethora of intricate biological mechanisms. Synonyms: N-(2-hydroxyacetyl)-b-neuraminic acid 2-(hydrogen 5-cytidylate); CMP-NeuGc. CAS No. 98300-80-2. Molecular formula: C20H31N4O17P. Mole weight: 630.45. | |
| CMP-N,N'-diacetyllegionaminic acid synthase | Isolated from the bacteria Legionella pneumophila and Campylobacter jejuni. Involved in biosynthesis of legionaminic acid, a sialic acid-like derivative that is incorporated into virulence-associated cell surface glycoconjugates which may include lipopolysaccharide (LPS), capsular polysaccharide, pili and flagella. Group: Enzymes. Synonyms: CMP-N,N'-diacetyllegionaminic acid synthetase; neuA (gene name); legF (gene name). Enzyme Commission Number: EC 2.7.7.82. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3295; CMP-N,N'-diacetyllegionaminic acid synthase; EC 2.7.7.82; CMP-N,N'-diacetyllegionaminic acid synthetase; neuA (gene name); legF (gene name). Cat No: EXWM-3295. | |
| CMP-Pseudaminic acid | CMP-Pseudaminic acid is a compound of immense value, serving as a fundamental building block for the bioresearch and development of pseudaminic acid, a vital constituent of bacterial glycosylated proteins. By impeding enzymatic development, CMP-Pseudaminic acid reveals promising prospects for research of bacterial infections triggered by notorious pathogens like Campylobacter jejuni and Helicobacter pylori. Synonyms: CMP-Pse. Molecular formula: C22H34N5O15P. Mole weight: 639.5. | |
| CMP-Sialic acid sodium salt | CMP-Sialic acid (CMP-Neu5Ac) sodium salt is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid sodium salt provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium salt is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CMP-Neu5Ac sodium salt. CAS No. 1007117-62-5. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-112942A. | |
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