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| Product | Description | |
|---|---|---|
| Clozapine Impurity 6 | Clozapine Impurity 6. Uses: For analytical and research use. CAS No. 1025951-76-1. Molecular formula: C20H21ClN4O. Mole weight: 368.86. Catalog: APB1025951761. |  |
| Clozapine Impurity 7 | Clozapine Impurity 7. Uses: For analytical and research use. CAS No. 60091-87-4. Molecular formula: C13H9ClN2O4. Mole weight: 292.68. Catalog: APB60091874. | |
| Clozapine Impurity 7 | Clozapine Impurity 7. Uses: For analytical and research use. Alternative Names: 2-(2-aminobenzamido)benzoic acid. CAS No. 612-34-0. Molecular formula: C14H12N2O3. Mole weight: 256.08. Catalog: APB612340. | |
| Clozapine Impurity 8 | Clozapine Impurity 8. Uses: For analytical and research use. CAS No. 67990-66-3. Molecular formula: C13H11ClN2O2. Mole weight: 262.69. Catalog: APB67990663. | |
| Clozapine Impurity 8 | Clozapine Impurity 8. Uses: For analytical and research use. Alternative Names: 2-(2-((4-chloro-2-nitrophenyl)amino)benzamido)benzoic acid. Molecular formula: C20H14ClN3O5. Mole weight: 411.80. Catalog: APB04323. | |
| Clozapine Impurity 9 | Clozapine Impurity 9. Uses: For analytical and research use. CAS No. 63687-95-6. Molecular formula: C17H18N4O. Mole weight: 294.36. Catalog: APB63687956. | |
| Clozapine N-oxide | Clozapine N-oxide is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide can't cross the blood-brain barrier[1][2][3][4]. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor (EC50=11 nM) agonist[5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 34233-69-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17366. |  |
| Clozapine N-oxide (CNO chemical) | CNO (Clozapine N-oxide) is a metabolite of Clozapine (GLXC-06516) and an agonist of human muscarinic designer receptors (Designer Receptors Exclusively Activated by Designer Drugs, DREADDs). Clozapine is a potent dopamine (DA) antagonist and a selective muscarinic M4 receptor agonist.Solutions are unstable and should be fresh-prepared. Group: Inhibitors. CAS No. 34233-69-7. Pack Sizes: 5mg. Product ID: S6887. Formula: C18H19ClN4O. Smiles: C[N+]1([O-])CCN(CC1)C2=NC3=C(NC4=CC=CC=C24)C=CC(=C3)Cl. |  United States; Europe |
| Clozapine N-oxide dihydrochloride | Clozapine N-oxide dihydrochloride is a major metabolite of Clozapine and a human muscarinic designer receptors (DREADDs) agonist. Clozapine N-oxide dihydrochloride activates the DREADD receptor hM3Dq and hM4Di. Clozapine N-oxide dihydrochloride cannot cross the blood-brain barrier[1][2][3][4]. Clozapine is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor (EC50=11 nM) agonist[5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2250025-93-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17366A. | |
| CLP257 | CLP257 is a selective K+-Cl cotransporter KCC2 activator with an EC50 of 616 nM. CLP257 is inactive against NKCC1, GABAA receptors, KCC1, KCC3 or KCC4. CLP257 restores impaired Cl transport in neurons with diminished KCC2 activity. CLP257 alleviates hypersensitivity in rats with neuropathic pain. CLP257 modulates plasmalemmal KCC2 protein turnover post-translationally[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1181081-71-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110143. | |
| CLP 257 | CLP 257 has been found to be a KCC2 K+-Cl- cotransporter activator and could alleviates hypersensitivity in rats with peripheral nerve injury. Synonyms: CLP 257; CLP-257; CLP257; (5Z)-5-[(4-Fluoro-2-hydroxyphenyl)methylene]-2-(tetrahydro-1-(2H)-pyridazinyl)-4(5H)-thiazolone. Grade: ≥98% by HPLC. CAS No. 1181081-71-9. Molecular formula: C14H14FN3O2S. Mole weight: 307.34. |  |
| CLP 257 | CLP 257. Group: Biochemicals. Grades: Purified. CAS No. 1181081-71-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| CLP290 | CLP290 is an orally available activator of the neuron-specific K+-Cl- cotransporter KCC2, displays potential for treatment of a wide range of neurological and psychiatric indications. CLP290 can significantly lower blood arginine-vasopressin (AVP) and glucose levels in STZ (HY-13753) rats[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1181083-81-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103023. | |
| CLP-3094 | CLP-3094 is a potent BF3 (binding function 3)-directed inhibitor of the androgen receptor (AR). It inhibits AR transcriptional activity (IC50 = 4 μM). CLP-3094 is also a selective, potent GPR142 antagonist. Synonyms: 2-{[2-(4-Chlorophenoxy)ethyl]thio}-1H-benzimidazole; 1H-Benzimidazole, 2-[[2-(4-chlorophenoxy)ethyl]thio]-. Grade: ≥95%. CAS No. 312749-73-8. Molecular formula: C15H13ClN2OS. Mole weight: 304.79. | |
| CLPP-2068 | CLPP-2068 is the orally active activator for human caseinolytic protease P (HsClpP) with an EC50 of 50.4 nM. CLPP-2068 exhibits anti-proliferative efficacy in OCI-LY10 cancer cell with an IC50 of 5.2 nM. CLPP-2068 decreases mitochondrial membrane potential, increases mitochondrial ROS levels, and induces mitochondrial dysfunction. CLPP-2068 arrests the cell cycle at G1 phase, and induces apoptosis in cell OCI-LY10. CLPP-2068 exhibits antitumor activity in mouse xenograft models[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3104462-62-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-173048. | |
| CLPP (240-248) | CLPP is a protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. It has low peptidase activity in the absence of CLPX. Synonyms: Caseinolytic Mitochondrial Matrix Peptidase Proteolytic Subunit (240-248); ATP-Dependent Clp Protease Proteolytic Subunit, Mitochondrial (240-248). | |
| CLS-011A | CLS-011A is a small molecule used as an antineoplastic and eye disorder therapy. Study indicated its excellent tolerance. Uses: Antineoplastic and eye disorder therapy. Synonyms: CLS 011A. | |
| Cl--transporting ATPase | A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. An animal and plant enzyme involved in the import of chloride anions. Group: Enzymes. Synonyms: Cl--translocating ATPase; Cl--motive ATPase. Enzyme Commission Number: EC 3.6.3.11. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4648; Cl--transporting ATPase; EC 3.6.3.11; Cl--translocating ATPase; Cl--motive ATPase. Cat No: EXWM-4648. |  |
| Cl-Trt-Resin | Cl-Trt-Resin. Synonyms: Tritylchloride Resin. | |
| Cluster Dextrin | Cluster Dextrin. |  CA, FL & NJ |
| CLZ-8 | CLZ-8 (Compound 8) is an orally active Mcl-1-PUMA interface inhibitor, with a Ki of 0.3 μM. CLZ-8 exhibits dual activity on reduce PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis in cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 678158-55-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122627. | |
| CM037 | CM037 is a highly selective and competitive ALDH1A1 inhibitor (IC50=4.6 μM). CM037 blocks the catalytic activity of ALDH1A1, thereby inhibiting the activation of the downstream HIF-1α/VEGF pathway. CM037 is mainly used to study the ALDH1A1-mediated regulation of cancer stem cells (CSCs) and angiogenesis, especially in breast cancer, showing the potential to inhibit tumor angiogenesis and stem cell characteristics[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: A37. CAS No. 896795-60-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-110294. | |
| CM1 | CM1 is an orally active iron chelator with high selectivity for iron(III). It can penetrate hepatocytes. CM1 is potentially used for patients with thalassaemia related iron overload and exhibits an inhibitory effect on the growth of Plasmodium falciparum (malaria parrasite; IC50 value 35 μM). Uses: The treatment of thalassaemia related iron overload. Synonyms: CM-1; CM 1; 1-(N-acetyl-6-aminohexyl)-3-hydroxy-2-methylpyridin-4-one. Grade: 99%. CAS No. 1643659-63-5. Molecular formula: C14H22N2O3. Mole weight: 266.34. | |
| CM 10 | CM 10 is an inhibitor of aldehyde dehydrogenase 1A (ALDH1A) inhibitor. It can induce a necroptotic phenotype and preferentially deplete CD133+ ovarian cancer stem cells in vitro. Synonyms: 2-(2-Propen-1-yl)-6-[[(1-propyl-1H-benzimidazol-2-yl)amino]methyl]phenol. Grade: ≥98% by HPLC. CAS No. 692269-09-3. Molecular formula: C20H23N3O. Mole weight: 321.42. | |
| CM-1758 | CM-1758 is a histone deacetylase (HDAC) inhibitor. CM-1758 inhibits tumor growth in vivo. CM-1758 induces acetylation of non-histone proteins in acute myeloid leukemia cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2256079-39-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161149. | |
| CM-24 | CM-24 is a humanized antibody expressed in CHO cells, targeting CEACAM1/CD66a. The predicted molecular weight (MW) of CM-24 is 145 kDa. The isotype control for CM-24 can refer to Human IgG1 kappa, Isotype Control (HY-P99001). Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: MK-6018. CAS No. 1783801-93-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990569. | |
| CM-272 | CM-272 is a first-in-class reversible and substrate-competitive dual inhibitor of G9a (GLP) and DNMTs. CM-272 inhibits cell proliferation and promotes apoptosis, inducing interferon-stimulated genes and immunogenic cell death in models of haematological neoplasia. Synonyms: CM 272; CM272. CAS No. 1846570-31-7. Molecular formula: C28H38N4O3. Mole weight: 478.63. | |
| CM-272 | CM-272 is a first-in-class, potent, selective, substrate-competitive and reversible dual G9a/DNA methyltransferases (DNMTs) inhibitor with antitumor activities. CM-272 inhibits G9a, DNMT1, DNMT3A, DNMT3B and GLP with IC50s of 8 nM, 382 nM, 85 nM, 1200 nM and 2 nM, respectively. CM-272 inhibits cell proliferation and promotes apoptosis, inducing IFN-stimulated genes and immunogenic cell death[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1846570-31-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101925. | |
| CM-3 | CM-3 is a synthetic construct with antibacterial activity. | |
| CM-352 | CM-352 has been found to be a MMP inhibitor that could probably be used as an antihemorrhagic agent with little influence in normal hemostatic function. Synonyms: CM352; CM 352; CM-352; (R)-N-hydroxy-2-((4-(4-(methylcarbamoyl)phenoxy)phenyl)sulfonyl)-8-azaspiro[4.5]decane-2-carboxamide. Grade: 98%. CAS No. 1542205-83-3. Molecular formula: C24H29N3O6S. Mole weight: 487.57. | |
| CM398 | CM398 is a highly selective, orally active Sigma-2 receptor ligand with a Ki value of 0.43 nM. CM398 ameliorates age-related macular degeneration. CM398 exerts analgesic effects on visceral pain, inflammatory pain and neuropathic pain. CM398 can be used in research related to age-related macular degeneration, neuropathic pain and inflammatory pain[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1121931-70-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145628. | |
| CM398 | CM398 has preferential affinity for sigma-2 receptor compared with sigma-1 receptor and at least four other neurotransmitter receptors sites, including the norepinephrine transporter. Synonyms: 1-(4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1h)-yl)butyl)-3-methyl-1h-benzo[d]imidazol-2(3h)-one. Grade: 98%. CAS No. 1121931-70-1. Molecular formula: C23H29N3O3. Mole weight: 395.49. | |
| CM-579 trihydrochloride | CM-579 trihydrochloride is a first-in-class reversible and dual inhibitor of G9a and DNMT, with IC50s of 16 nM and 32 nM, respectively. It has potent in vitro cellular activity in a wide range of cancer cells. Synonyms: 6-Methoxy-2-(5-methyl-2-furyl)-N-[(1-methyl-4-piperidinyl)methyl]-7-[3-(1-pyrrolidinyl)propoxy]-4-quinolinamine trihydrochloride; 4-Quinolinamine, 6-methoxy-2-(5-methyl-2-furanyl)-N-[(1-methyl-4-piperidinyl)methyl]-7-[3-(1-pyrrolidinyl)propoxy]-, hydrochloride (1:3). Grade: ≥95%. Molecular formula: C29H43Cl3N4O3. Mole weight: 602.04. | |
| CMA | CMA is a murine-selective agonist of STING. It triggers type I IFN response in murine macrophages, without effect on human STING signaling. Synonyms: 9-Oxo-10(9H)-acridineacetic acid. Grade: ≥98% by HPLC. CAS No. 38609-97-1. Molecular formula: C15H11NO3. Mole weight: 253.25. | |
| CMB-087229 | CMB-087229 is a mutant superoxide dismutase 1 (SOD1) protein aggregation inhibitor with IC50 of 67 nM, which can be used in the research of amyotrophic lateral sclerosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1227692-67-2. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg. Product ID: HY-148901. | |
| CMC2.24 | CMC2.24 is an orally active tricarbonylmethane agent. It is effective against pancreatic tumor in mice by inhibiting Ras activation and its downstream effector ERK1/2 pathway. CMC2.24 is also a potent inhibitor of zinc-dependent MMPs with IC50s ranging from 2.0-69 μM. Synonyms: TRB-N0224. Grade: 96%. CAS No. 1255639-43-0. Molecular formula: C26H21NO5. Mole weight: 427.45. | |
| CMC-Na | CMC-Na (Sodium carboxymethyl cellulose) is one of the important modified cellulose, a water-soluble cellulose, which is widely used in many application of food, pharmaceuticals, detergent, paper coating, dispersing agent, and others. Its addition possibly increases the hydrogenation and dehydrogenation features of Magnesium. Group: Inhibitors. Alternative Names: Sodium carboxymethyl cellulose. CAS No. 9004-32-4. Pack Sizes: 5g. Product ID: S6703. Smiles: CC(=O)O.C(C(C(C(C(C=O)O)O)O)O)O.[Na]. | United States; Europe |
| CMC-Na | CMC-Na (Sodium carboxymethyl cellulose) is one of the important modified cellulose, a water-soluble cellulose, which is widely used in many application of food, pharmaceuticals, detergent, paper coating, dispersing agent, and others. CAS No. 9004-32-4. Product ID: PE-0150. Category: Binder Excipients. Product Keywords: Pharmaceutical Excipients; Solid Dosage Form; Binder Excipients; CMC-Na; PE-0150; 9004-32-4; 9004-32-4. Purity: 0.9972. Synonym(s): Sodium carboxymethyl cellulose. Storage: 3 years -20°C powder. |  |
| CMD178 | CMD178 is a lead peptide that can sustainably reduce the expression of Foxp3 and STAT5 induced by IL-2/ S IL-2Rα signal. CMD178 is also a STAT5 inhibitor and inhibits the development of Treg cells. Synonyms: H-Arg-Phe-Lys-Phe-Tyr-OBn; L-arginyl-L-phenylalanyl-L-lysyl-L-phenylalanyl-L-tyrosine benzyl ester; RFKFY-OBn; CMD 178; CMD-178. Grade: ≥98%. CAS No. 2703745-80-4. Molecular formula: C46H59N9O7. Mole weight: 850.03. | |
| CMD178 TFA | CMD178 (TFA) is a peptide, which consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/sIL-2Rα signaling. Synonyms: H-Arg-Phe-Lys-Phe-Tyr-OBn.TFA; L-arginyl-L-phenylalanyl-L-lysyl-L-phenylalanyl-L-tyrosine benzyl ester trifluoroacetic acid; RFKFY-OBn.TFA; CMD 178 TFA; CMD-178 TFA. Grade: 98%. CAS No. 2703745-81-5. Molecular formula: C46H59N9O7.C2HF3O2. Mole weight: 964.05. | |
| CM-Dextran sodium salt | CM-Dextran sodium salt. CAS No. 39422-83-8. |  |
| c-Met-IN-1 | c-Met-IN-1, a potent and selective c-Met inhibitor (IC50 = 1.1 nM), has antitumor activity. Synonyms: N-[3-Fluoro-4-[6-methoxy-7-[3-(4-methylpiperazino)propoxy]quinoline-4-yloxy]phenyl]-1-(2-methoxyphenyl)-1H-imidazole-4-carboxamide; 1H-Imidazole-4-carboxamide, N-[3-fluoro-4-[[6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-4-quinolinyl]oxy]phenyl]-1-(2-methoxyphenyl)-. Grade: ≥95%. CAS No. 2084836-84-8. Molecular formula: C35H37FN6O5. Mole weight: 640.70. | |
| c-Met-IN-2 | c-Met-IN-2, a potent, selective and orally available c-Met inhibitor (IC50 = 0.6 nM), has antitumor activity. Synonyms: 2-[4-(1-{1-[7-Fluoro-3-(1-methyl-1H-pyrazol-4-yl)-6-quinolinyl]ethyl}-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl]ethanol; 1H-Pyrazole-1-ethanol, 4-[1-[1-[7-fluoro-3-(1-methyl-1H-pyrazol-4-yl)-6-quinolinyl]ethyl]-1H-1,2,3-triazolo[4,5-b]pyrazin-6-yl]-. Grade: ≥95%. CAS No. 1635406-73-3. Molecular formula: C24H21FN10O. Mole weight: 484.49. | |
| c-Met inhibitor 1 | c-Met inhibitor 1 is an inhibitor of the c-Met receptor signaling pathway useful for the treatment of cancer including gastric, glioblastoma, and pancreatic cancer. Synonyms: c-Met inhibitor 1; c Met inhibitor 1. Grade: >98%. CAS No. 1357072-61-7. Molecular formula: C17H14N8S. Mole weight: 362.41. | |
| CMF019 | CMF019 is an orally active, potent and small molecule agonist at Apelin receptor (APJ) with G protein bias. CMF019 binds to APJ with pKi values of 8.58, 8.49 and 8.71 for human, rat, and mouse, respectively. CMF019 mimics the beneficial cardiovascular actions of apelin in rodents[1]. Apelin receptor (APJ) is a G protein-coupled receptor (GPCR) activated by the endogenous peptide apelin. CMF019 is promising for research of chronic diseases, such as, pulmonary arterial hypertension[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1586787-08-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103080. | |
| CMG-101 | CMG-101 is a novel selective inhibitor of mTORC1/2. Studies suggest that CMG-101 would overcome the drug resistance of mTORC1 inhibitor through the activation of signal transduction pathways via mTORC2. CMG-101 is promisingly to be a antitumor drug. Uses: Potential antitumor drug. Synonyms: CMG101; CMG 101. | |
| CM-H2DCFDA | CM-H2DCFDA is a derivative of H2DCFDA (HY-D0940). CM-H2DCFDA can be used to determine cellular oxidant levels (Ex/Em: 495/530 nm). CM-H2DCFDA is light-sensitive[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 850013-49-9. Pack Sizes: 50 μg. Product ID: HY-D1713. | |
| CMHPG | CMHPG. |  |
| CMI-392 | CMI-392 is a dual antagonist of 5-lipoxygenese (IC50= 100 nM) and platelet-activating factor (PAF) receptor (IC50= 10 nM). Uses: Lipoxygenase inhibitors. Synonyms: 3-[[2-[2-(4-chlorophenyl)sulfanylethoxy]-3-methoxy-5-[(2S,5S)-5-(3,4,5-trimethoxyphenyl)oxolan-2-yl]phenyl]methyl]-1-hydroxy-1-methylurea; 2-(3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N-hydroxyureidyl)methylphenyl)-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran; CMI 392; CMI-392. CAS No. 205654-37-1. Molecular formula: C31H37ClN2O8S. Mole weight: 633.15. | |
| CMI-977 | CMI-977, an oxolan compound, has been found to be a 5-Lipoxygenases inhibitor and was once studied as an antiasthmatic agent. Synonyms: CMI-977; CMI 977; CMI977; LPD-977; LPD 977; LPD977; MLN-977; MLN977; MLN 977; 1-[4-[(2S,5S)-5-[(4-fluorophenoxy)methyl]oxolan-2-yl]but-3-ynyl]-1-hydroxyurea. Grade: 98%. CAS No. 175212-04-1. Molecular formula: C16H19FN2O4. Mole weight: 322.34. | |
| CMIT/MIT (14.5% in water) | CMIT/MIT is a CMIT and MIT mixture. CMIT and MIT are powerful synthetic biocidal substances. CMIT and MIT are used as preservatives in various cosmetics and industrial products. CMIT and MIT are present in many water-soluble consumer products, such as shampoos, toothpastes. CMIT/MIT (3:1 mixture of CMIT and MIT) produces mitochondrial ROS via inhibiting mitochondrial complex I and II. CMIT/MIT (in 3:1 ratio) induces neurotoxicity through the upregulation of the MAPKs signaling pathways. CMIT/MIT can be used in the research of respiratory diseases and neuroblastoma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CMI/MI. CAS No. 55965-84-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 g; 500 g; 1 k g. Product ID: HY-W017982. | |
| CMK | CMK is a RSK2 kinase inhibitor. Its IC50 value for Cdc5(L158G) is 36 nM. It is used in the preparation of serine/threonine kinase inhibitors. Uses: Cmk is used in the preparation of serine/threonine kinase inhibitors. Synonyms: 1-(4-Amino-7-(3-hydroxypropyl)-5-(p-tolyl)-7h-pyrrolo[2,3-d]pyrimidin-6-yl)-2-chloroethanone. Grade: 95%. CAS No. 821794-90-5. Molecular formula: C18H19ClN4O2. Mole weight: 358.82. | |
| CMK | CMK is a RSK2 kinase inhibitor which exhibits similar potency but less chemical stability compared with FMK. Uses: Scientific research. Category: Signaling pathways. CAS No. 821794-90-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-52101. | |
| CMK-3 | CMK-3. CAS No. 7440-44-0. Product ID: ACM7440440-216. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| CMK-8 | CMK-8. CAS No. 7440-44-0. Product ID: ACM7440440-161. Alfa Chemistry - ISO 9001:32057 Certified. | |
| CMKLR1 antagonist 1 | CMKLR1 antagonist 1 (compound S-26d) is a potent and orally active chemokine-like receptor 1 (CMKLR1) antagonist, with a pIC50 value of 7.44 in hCMKLR1-transfected CHO cells. CMKLR1 antagonist 1 can be used for psoriasis and metabolic diseases research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3033101-08-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156460. | |
| CMLD012072 | CMLD012072, an amidino-rocaglates, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor with strong antitumor activity. It can induce RNA to clamp eIF4A1 and eIF4A2. Synonyms: Methyl (3aR,4R,5S,5aR,10bR)-2-cyclopropyl-3a-hydroxy-8,10-dimethoxy-5a-(4-methoxyphenyl)-5-phenyl-3a,4,5,5a-tetrahydro-1H-[1]benzofuro[3',2':1,5]cyclopenta[1,2-d]imidazole-4-carboxylate; 1H-Benzofuro[3',2':1,5]cyclopent[1,2-d]imidazole-4-carboxylic acid, 2-cyclopropyl-3a,4,5,5a-tetrahydro-3a-hydroxy-8,10-dimethoxy-5a-(4-methoxyphenyl)-5-phenyl-, methyl ester, (3aR,4R,5S,5aR,10bR)-. Grade: ≥95%. CAS No. 2368900-33-6. Molecular formula: C32H32N2O7. Mole weight: 556.61. | |
| CMLD012073 | CMLD012073, an amidino-rocaglates and a potent eukaryotic initiation factor 4A (eIF4A) inhibitor, inhibits NIH/3T3 cells growth with an IC50 of 10 nM. It inhibits eukaryotic translation initiation by modifying the behavior of the RNA helicase (eIF4A). Synonyms: 3H-Benzofuro[3',2':1,5]cyclopent[1,2-d]imidazole-4-carboxylic acid, 3a,4,5,5a-tetrahydro-3a-hydroxy-8,10-dimethoxy-5a-(4-methoxyphenyl)-2-methyl-5-phenyl-, methyl ester, (3aR,4R,5S,5aR,10bR)-; Methyl (3aR,4R,5S,5aR,10bR)-3a-hydroxy-8,10-dimethoxy-5a-(4-methoxyphenyl)-2-methyl-5-phenyl-3a,4,5,5a-tetrahydro-1H-[1]benzofuro[3',2':1,5]cyclopenta[1,2-d]imidazole-4-carboxylate. Grade: ≥97%. CAS No. 2368900-32-5. Molecular formula: C30H30N2O7. Mole weight: 530.57. | |
| CML-d2 | CML-d2. Synonyms: N-epsilon-carboxy[D2]methyl-L-Lysine; H-L-Lys(Cm)-OH-d2; H-Lys(Cm)-OH-d2; (S)-2-amino-6-(carboxy[D2]methylamino)hexanoic acid. Molecular formula: C8H14D2N2O4. Mole weight: 206.24. | |
| CMLD-2 | CMLD-2 is an inhibitor of HuR-ARE interaction. CMLD-2 induces apoptosis and exhibits antitumor activity in different cancer cells as colon, pancreatic, thyroid and lung cancer cell lines. Synonyms: 5,7-dimethoxy-8-(1-(4-methoxyphenyl)-3-oxo-3-(pyrrolidin-1-yl)propyl)-4-phenyl-2H-chromen-2-one. Grade: 98%. CAS No. 958843-91-9. Molecular formula: C31H31NO6. Mole weight: 513.58. | |
| CMLD-2 | CMLD-2, an inhibitor of HuR-ARE interaction, competitively binds HuR protein disrupting its interaction with adenine-uridine rich elements (ARE)-containing mRNAs (Ki=350 nM). CMLD-2 induces apoptosis exhibits antitumor activity in different cancer cells as colon, pancreatic, thyroid and lung cancer cell lines. Hu antigen R (HuR) is an RNA binding protein, can regulate target mRNAs stability and translation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 958843-91-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-124828. | |
| Cm-p1 | Cm-p1 was found in marine snail Cenchritis muricatus. This peptide demonstrated the capacity to prevent the development of yeasts and filamentous fungi. Otherwise, Cm-p1 displayed no toxic effects against mammalian cells. | |
| CMP5 | CMP5 is a potent and selective PRMT5 inhibitor suppressing EBV-driven B-lymphocyte transformation while leaving normal B cells unaffected. Inhibition of PRMT5 effetively blocked recall T cell responses, reduced inflammation in delayed-type hypersensitivity and clinical disease in experimental autoimmune encephalomyelitis mouse models. Synonyms: CMP5; CMP 5; CMP-5; 1-(9-ethylcarbazol-3-yl)-N-(pyridin-2-ylmethyl)methanamine Hydrochloride; AKOS032401780. Grade: 99%. CAS No. 1030021-40-9. Molecular formula: C20H22N3.HCl. Mole weight: 351.87. | |
| CMP-5 | CMP5 is a potent, selective and specific inhibitor of PRMT5, but has no activity against PRMT1, PRMT4 and PRMT7 enzymes. CMP5 selectively blocks S2Me-H4R3 by inhibiting the activity of PRMT5 methyltransferase on histone preparations. It prevents epstein-barr virus (EBV)-driven B-lymphocyte transformation, but does not affect normal B cells. Synonyms: 1-(9-ethyl-9H-carbazol-3-yl)-N-(pyridin-2-ylmethyl)methanamine; PRMT5-IN-5; N-[(9-ethyl-9H-carbazol-3-yl)methyl]-N-(2-pyridinylmethyl)amine; 9H-Carbazole-3-methanamine, 9-ethyl-N-(2-pyridinylmethyl)-. Grade: ≥98%. CAS No. 880813-42-3. Molecular formula: C21H21N3. Mole weight: 315.41. | |
| CMP-5 2HCl | CMP-5 2HCl is a repellent. The EC100 of CMP-5 2HCl in vitro against H. contortus is 5 μM. Synonyms: 9H-Carbazole-3-methanamine, 9-ethyl-N-(2-pyridinylmethyl)-,hydrochloride (1:2). Grade: >98.0%. CAS No. 2309409-79-6. Molecular formula: C21H23Cl2N3. Mole weight: 388.34. | |
| CMP8 | CMP8 is a selective ligand for the estrogen receptor, which can bind to the ligand binding domain of the estrogen receptor. The IC50 values of CMP8 for mutant MGERα, MGRERα and wild-type hERα and hERβ are 29 nM, 41 nM, 1100 nM and 2200 nM, respectively. Grade: 98%. CAS No. 851107-28-3. Molecular formula: C33H34ClNO3. Mole weight: 528.1. | |
| CMP-9-fluoresceinyl-NeuAc | CMP-9-fluoresceinyl-NeuAc, is shown to be a suitable donor substrate for sialyltransferase, which belongs to glycosyltransferase family 29. Synonyms: N-Acetyl-9-deoxy-9-[[[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]thioxomethyl]amino]-2-(hydrogen 5'-cytidylate) β-Neuraminic Acid; 5-(Acetylamino)-3,5,9-trideoxy-9-[[[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]thioxomethyl]amino]-D-glycero-β-D-galacto-2-Nonulopyranosonic Acid 2-(Hydrogen 5'-cytidylate); Spiro[isobenzofuran-1(3H),9'-[9H]xanthene] D-glycero-β-D-galacto-2-nonulopyranosonic acid Deriv. CAS No. 118720-35-7. Molecular formula: C41H43N6O20PS. Mole weight: 1002.85. | |
| CMP-9-O-acetyl-N-acetylneuraminic acid | CMP-9-O-acetyl-N-acetylneuraminic acid is an indispensable compound, having multifarious utilities in an array of maladies, ranging from influenza to viral infections and autoimmune disorders. The distinctive attributes it possesses render it an imperative constituent for investigating sialic acid metabolism and glycoconjugate. Synonyms: CMP-9-O-Ac-Neu5Ac. Molecular formula: C22H33N4O16P. Mole weight: 640.49. | |
| CMP-C9-Azido-Sialic Acid sodium | CMP-C9-Azido-Sialic Acid is a synthetic derivative belonging to the sialic acid family found in many types of glycoproteins and glycolipids. Grade: ≥85%. Molecular formula: C20H31N7NaO15P. Mole weight: 663.47. | |
| CMP-CP | CMP-CP is a non-hydrolytic analogue of CDP. It is commonly used as a starting structure in the synthesis of α/β hydrolysis-resistant tri- and polyphosphates. Synonyms: Cytidine- 5'- O- (α, β- methylene)diphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 101536-15-6. Molecular formula: C10H17N3O10P2 (free acid). Mole weight: 401.2 (free acid). | |
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