A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Cortistatin-8. Group: Biochemicals. Grades: Purified. CAS No. 485803-62-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Cortodoxone
Cortodoxone (11-Deoxycortisol; cortexolone) is a glucocorticoid steroid hormone and also is a glucocorticoid antagonist. Cortodoxone increases tryptophan oxygenase (TO) activity and induces the secretion of corticosterone. Cortodoxone regulates T cell proliferation and activation[1][2]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: 11-Deoxycortisol; cortexolone; Reichstein's substance S. CAS No. 152-58-9. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-77839.
Cortodoxone
Cortodoxone, a glucocorticoid receptor antagonist, is an intermediate which can be oxygenated to cortisol. Uses: Glucocorticoid receptor binding. Synonyms: (8R,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one 11 Deoxycortisol 11 Desoxycortisol 11 Desoxycortisone 11-Deoxycortisol 11-Desoxycortisol 11-Desoxycortisone Cortexo. Grade: >98.0%(LC). CAS No. 152-58-9. Molecular formula: C21H30O4. Mole weight: 346.46.
Corydaline
Corydaline. Group: Biochemicals. Alternative Names: 2,3,9,10-Tetramethoxy-13-methylberbine, 8CI; Corydalis A. Grades: Plant Grade. CAS No. 518-69-4. Pack Sizes: 20mg. Molecular Formula: C22H27NO4, Molecular Weight: 369.454. US Biological Life Sciences.
Worldwide
corydaline synthase
Also acts on 7,8-dihydropalmatine. Group: Enzymes. Enzyme Commission Number: EC 2.1.1.147. CAS No. 155807-67-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1743; corydaline synthase; EC 2.1.1.147; 155807-67-3. Cat No: EXWM-1743.
Corydalis Powder
Corydalis Powder.
CA, FL & NJ
Corydalmine
Corydalmine,an natural plant alkaloid isolated from roots of Corydalis chaerophylla, can inhibit spore germination of some plant pathogenic as well as saprophytic fungi e.g. Alternaria brassicae, A. brassicicola, A. solani, Curvularia lunata, C. maculans, C. sp., C. pallscens, Erysiphe pisi, Fusarium udum, Helminthosporium species,H. penniseti and a Heterosporium species; it can significantly inhibit spore germination of all the fungi at 100 to 1500 ppm, it is effective against all the fungi at 1500 ppm. C. l-Corydalmine exhibits activity of potent analgesic in preclinical models, it is under development as an oral analgesic agent. Uses: Anti-bacterial. Synonyms: (-)-Kikemanine; (13aS)-5,8,13,13a-Tetrahydro-2,3,9-trimethoxy-6H-dibenzo[a, g]quinolizin-10-ol; Kikemanin; Kikemanine; Schefferine. Grade: >95%. CAS No. 30413-84-4. Molecular formula: C20H23NO4. Mole weight: 341.4.
Corydine
Botanical Source: Group: Biochemicals. Alternative Names: (S)-form. Grades: Plant Grade. CAS No. 476-69-7. Pack Sizes: 10mg, 20mg. US Biological Life Sciences.
Worldwide
Corydine
Corydine is a HIV-1 reverse transcriptase inhibitor and μ-opioid receptor (MOR) agonist, with an IC50 of 356.7 μg/mL against HIV-1 reverse transcriptase, an EC50 of 0.51 μM for MOR, and a Ki of 2.82 μM for MOR. Corydine produces antinociceptive effects by inhibiting acetic acid-induced writhing behavior in a MOR-dependent manner. Corydine inhibits the proliferation of cancer cells, mitogen-stimulated lymphocytes and IL-2-dependent cells. Corydine can be used in studies related to human immunodeficiency virus infection, visceral pain, leukemia, melanoma, bladder cancer and colon adenocarcinoma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 476-69-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N2571.
Corylifol A
Corylifol A. Group: Biochemicals. Alternative Names: 3?-Geranyl-4?,7-dihydroxyisoflavone; Corylinin. Grades: Plant Grade. CAS No. 775351-88-7. Pack Sizes: 20mg. Molecular Formula: C25H26O4, Molecular Weight: 390.472. US Biological Life Sciences.
Worldwide
Corylifol C
Corylifol C isolated from the seeds of Psoralea corylifolia L. Synonyms: 2-(3,4-Dihydroxyphenyl)-7-hydroxy-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one. Grade: 0.95. CAS No. 775351-91-2. Molecular formula: C20H18O5. Mole weight: 338.4.
Corylifolinin
Corylifolinin. Group: Biochemicals. CAS No. 20784-50-3. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Corylin
Corylin is a major bioactive compound isolated from Psoralea corylifolia L. It is antibiotic or anticancer compound. Uses: Anti-biotic; anti-cancer. Synonyms: 7-Hydroxy-2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one. Grade: >98%. CAS No. 53947-92-5. Molecular formula: C20H16O4. Mole weight: 320.34.
Corylin
Corylin. Group: Biochemicals. Grades: Plant Grade. CAS No. 53947-92-5. Pack Sizes: 20mg. Molecular Formula: C20H16O4, Molecular Weight: 320.34. US Biological Life Sciences.
It is produced by the strain of Coryneum modonium AB 2020T-223. It is a glycolipid antibiotic with antifungal activity. The antifungal spectrum and antifungal activity are similar to Papulacandin. Synonyms: D-Glucitol, 1,5-anhydro-1-C-(2,4-dihydroxy-6-(hydroxymethyl)phenyl)-4-O-(6-O-((2E,4Z)-1-oxo-2,4-decadienyl)-beta-D-galactopyranosyl)-, 3-((2E,4E)-7-hydroxy-2,8-dimethyl-2,4-decadienoate)-. CAS No. 199169-60-3. Molecular formula: C41H60O16. Mole weight: 808.90.
Corynecin ?
It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Synonyms: N-[(1R,2R)-1-[(Acetyloxy)methyl]-2-hydroxy-2-(4-nitrophenyl)ethyl]acetamide. Grade: >99% by HPLC. CAS No. 40958-11-0. Molecular formula: C13H16N2O6. Mole weight: 296.28.
Corynecin I
It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Synonyms: N-[(1R,2R)-2-Hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide; D-threo-2-Acetamido-1-(4-nitrophenyl)-1,3-propanediol; D-threo-2-Acetamido-1-p-nitrophenyl-1,3-propanediol; n-acetyl-p-nitrophenylserinol. Grade: >99% by HPLC. CAS No. 4423-58-9. Molecular formula: C11H14N2O5. Mole weight: 254.24.
Corynecin II
It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Synonyms: D-threo-1-p-Nitrophenyl-2-propionamido-1,3-propanediol; N-[(1R,2R)-2-Hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]propanamide; d-threo-2-(Propionamido)-1-(p-nitrophenyl)-1,3-propanediol. Grade: >99% by HPLC. CAS No. 35098-52-3. Molecular formula: C12H16N2O5. Mole weight: 268.27.
Corynecin III
It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Synonyms: Methamphenicol; dimethylamphenicol; N-[(1R,2R)-1-(Hydroxymethyl)-2-hydroxy-2-(4-nitrophenyl)ethyl]-2-methylpropanamide; N-[(1R,2R)-2-Hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-2-methylpropanamide; d-threo-2-Isobutyramido-1-(p-nitrophenyl)-1,3-propanediol; N-[β-Hydroxy-α-(hydroxymethyl)-p-nitrophenethyl]-2-methyl-D-threo-propionamide. Grade: >99% by HPLC. CAS No. 18048-95-8. Molecular formula: C13H18N2O5. Mole weight: 282.29.
Corynecin V
It is produced by the strain of Corynebacterium KY-4339. It has weak activity against gram-positive bacteria and gram-negative bacteria. Synonyms: [R-(R*,R*)]-N-[1-[(Acetyloxy)methyl]-2-hydroxy-2-(4-nitrophenyl)ethyl]-propanamide. Grade: >99% by HPLC. CAS No. 40958-12-1. Molecular formula: C14H18N2O6. Mole weight: 310.30.
Corynoline
Corynoline. Group: Biochemicals. Grades: Plant Grade. CAS No. 18797-79-0. Pack Sizes: 20mg. Molecular Formula: C21H21NO5, Molecular Weight: 367.39. US Biological Life Sciences.
Worldwide
Corynoline
Corynoline, which is found in the tubers of Corydalis ambigua, is an acetylcholinesterase inhibitor. Uses: Sedative/anti-leptospira. Synonyms: Corynoline; [1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-6-ol,5b,6,7,12b,13,14-hexahydro-5b,13-, dimethyl-, (5bR,6S,12bR)-; (5bR)-5bα,13-Dimethyl-5bα,6,7,12bα,13,14-hexahydro[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine-6β-ol; 13-Methylchelidonan-11β-ol. Grade: >98%. CAS No. 18797-79-0. Molecular formula: C21H21NO5. Mole weight: 367.4.
Corynoxeine
Corynoxeine. Group: Biochemicals. Grades: Plant Grade. CAS No. 630-94-4. Pack Sizes: 20mg. Molecular Formula: C22H26N2O4, Molecular Weight: 382.45. US Biological Life Sciences.
Worldwide
Corynoxidine
Corynoxidine is an antibacterial alkaloid isolated from the roots of Stephania epigaea. Corynoxidine also acts as a dose-dependent acetylcholinesterase inhibitor. Synonyms: Tetrahydropalmatine N-oxide; (7S,13aS)-2,3,9,10-tetramethoxy-7-oxido-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinolin-7-ium. Grade: 98.0%. CAS No. 57906-85-1. Molecular formula: C21H25NO5. Mole weight: 371.433.
Corynoxine
Corynoxine is an enantiomer of Corynoxine B. It induces autophagy in different neuronal cell lines, including N2a and SHSY-5Y cells. By inducing autophagy, it promotes the clearance of wild-type and A53T α-syn in inducible PC12 cells. It also significantly decreased locomotor activity after oral administration to mice. Synonyms: (16E)-16,17-Didehydro-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester. Grade: >98%. CAS No. 6877-32-3. Molecular formula: C22H28N2O4. Mole weight: 384.47.
Corynoxine B
Corynoxine B. Group: Biochemicals. Grades: Plant Grade. CAS No. 17391-18-3. Pack Sizes: 10mg. Molecular Formula: C22H28N2O4, Molecular Weight: 384.48. US Biological Life Sciences.
Worldwide
Corypalmine
Corypalmine is an alkaloid identified in the dried tubers of Corydalis Decumbens Pers, with an oral bioavailability of 4.6% in mice. Corypalmine exhibits poor gastrointestinal absorption properties, which correlate with its high hydrophilicity and low permeability[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 27313-86-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0654.
Corytuberine
Corytuberine. Group: Biochemicals. Alternative Names: (6aS)-5,6,6a,7-Tetrahydro-2,10-dimethoxy-6-methyl-4H-dibenzo[de,g]quinoline-1,11-diol; 2,10-Dimethoxy-6a-a-aporphine-1,11-diol; (+)-Corytuberine. Grades: Highly Purified. CAS No. 517-56-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C19H21NO4. US Biological Life Sciences.
Worldwide
Corza6
Corza6 is a de novo peptide inhibitor that inhibits hHv1 in human spermatozoa and suppresses the acrosome reaction. Synonyms: C6; Ser-Ser-Thr-Cys-Ile-Pro-Ser-Gly-Gln-Pro-Cys-Ala-Asp-Ser-Asp-Asp-Cys-Cys-Glu-Thr-Phe-His-Cys-Lys-Trp-Val-Phe-Phe-Thr-Ser-Lys-Phe-Met-Cys-Arg-Arg-Val-Trp-Gly-Lys-Asp (Disulfide bond Cys4/Cys18, Cys11/Cys23, Cys17/Cys34). Molecular formula: C203H293N55O61S7. Mole weight: 4704.52.
Cos-7 Transfection Reagent
Transfection Reagent for COS7 Kidney Fibroblast Cells. Optimized transfection protocol provided for transfection of siRNA, DNA, mRNA, and microRNA. Transfection Reagents. Transfection Enhancer. Complex Condenser. Uses: Transfection of DNA, RNA, protein and small molecules. Product ID: 1740.
Nevada, Texas, USA
Cosalane
Cosalane (NSC 658586) is a CCR7 (IC50 = 2.43 μM) and CXCR2 antagonist (IC50 = 0.66 μM). Cosalane is an inhibitor of HIV replication with a wide range of activity against HIV-1 isolates, HIV-2, Rauscher murine leukemia virus, HSV-1, HSV-2 and human cytomegalovirus. Cosalane inhibits both attachment of gp120 to CD4. Cosalane inhibits human and murine CCR7 in response to both CCL19 and CCL21 agonists. Cosalane can be studied in research for HIV or attenuating acute graft-versus-host disease (aGVHD) in allogeneic hematopoietic stem cell transplantation (HSCT)[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 658586. CAS No. 154212-56-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-120427.
Cosan 528
Cosan-528 is a fungicide which is active against the fungus A. pullulans (MIC = 8 ppm). Cosan-528 completely inhibits the growth of A. pullulans, A. niger, and Penicillium on paint-coated white pine sapwood for at least six weeks. Synonyms: Cosan-528; Cosan528; 2-Chloro-N-(2-methyl-4-bromophenyl)acetamide. CAS No. 96686-51-0. Molecular formula: C9H9BrClNO. Mole weight: 262.54.
Cosibelimab
Cosibelimab (CK-301) is a high-affinity, fully human PD-L1-blocking monoclonal antibody that binds PD-L1 and blocks its interaction with PD-1. Cosibelimab exhibits antitumor efficacy[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CK-301; TG-1501. CAS No. 2216751-26-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99833.
They have been carefully selected for compatibility, style, and quality to ensure that they meet a variety of customer needs while remaining immediately available for our clients. Product ID: PM-056. Category: Dropper Bottle. Product Keywords: Plastic Packaging; Cosmetic Serum Bottle; PM-056; Dropper Bottle;. Administration route: empaty serum bottle is a lightweight form of cosmetic packaging which is highly recyclable.
Cosmomycin C
It is an anthracycline antibiotic produced by the strain of Streptomyces cyaneus (A-447). It has anti-tumor and gram-positive bacteria activity. It can inhibit the growth of P388 murine lymphocytic leukemia cells. Synonyms: Antibiotic A-447B; (3''S)-3''-Hydroxycytorhodin A; 3B-Hydroxycytorhodin A; A-447B; β-Rhodomycin S2; 5,12-Naphthacenedione, 8-ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-10-[[2,3,6-trideoxy-4-O-[2,6-dideoxy-4-O-[(2S,5S,6S)-tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]-3-(dimethylamino)-a-L-lyxo-hexopyranosyl]oxy]-7-[[2,3,6-trideoxy-3-(dimethylamino)-4-O-[(2S,5S,6S)-tetrahydro-6-methyl-5-[[(2S,5S,6S)-tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]oxy]-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]oxy]-,(7R,8R,10S)-. CAS No. 55945-22-7. Molecular formula: C60H88N2O21. Mole weight: 1173.34.
Cosmomycin D
It is an anthracycline antibiotic produced by the strain of Streptomyces cyaneus (A-447). It has anti-tumor activity. It can inhibit the growth of P388 murine lymphocytic leukemia cells. Synonyms: (3''S,3'''''S)-3'',3'''''-Dihydroxycytorhodin A; 1-Deoxyobelmycin D; 3B,3E-Dihydroxycytorhodin A; A-447A; Antibiotic A-447A; 5,12-Naphthacenedione, 8-ethyl-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-7,10-bis((2,3,6-trideoxy-4-O-(2,6-dideoxy-4-O-((2S,5S,6S)-tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl)-alpha-L-lyxo-hexopyranosyl)-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-, (7R,8R,10S)-. CAS No. 95676-81-6. Molecular formula: C60H88N2O22. Mole weight: 1189.34.
Cosmosiin also called Apigenin 7-O-glucoside, is a natural flavonoid found in the flowers of Cosmos bipinnatus. Cosmosiin exhibits the activities of anti-HIV, anti-proliferative and antioxidant, the compound may be beneficial for diabetic complications through their enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4 translocation. Uses: Anti-proliferative; antioxidant; anti-hiv. Synonyms: Apigenin 7-O-glucoside. Grade: >98%. CAS No. 578-74-5. Molecular formula: C21H20O10. Mole weight: 432.39.
Co Solvent Polyamide Resin ALFA01
This product is a low freezing point benzene soluble polyamide resin with good cold resistance (i.e. good resistance to gelation) and indoor temperature frost transfer. The resin has good adhesion to most treated films and is significantly more compatible with NC than other homogeneous products.
Co Solvent Polyamide Resin ALFA02
Co-solvent polyamide resins are soluble in alcohol mixtures or mixtures of alcohols and aliphatic hydrocarbon co-solvents.
Co Solvent Polyamide Resin ALFA03
Co-solvent polyamide resins are soluble in alcohol mixtures or mixtures of alcohols and aliphatic hydrocarbon co-solvents.
Co Solvent Polyamide Resin ALFA04
Co-solvent polyamide resins are soluble in alcohol mixtures or mixtures of alcohols and aliphatic hydrocarbon co-solvents.
Co Solvent Polyamide Resin ALFA05
This polyamide resin is an alcohol-soluble/co-solvent resin with excellent solvent release and blocking properties. It was developed for mold release paints, but can also be used as a modified resin to improve hardness.
Co Solvent Polyamide Resin ALFA06
This resin is an alcohol-soluble/co-solvent resin with excellent solvent release and blocking properties. This polyamide resin was developed for mold release varnishes and has the lowest solution viscosity but fast solvent release.
Co Solvent Polyamide Resin ALFA07
This polyamide resin is an alcohol-soluble/co-solvent type resin with low-temperature gel resistance and good compatibility with modified resins.
Co Solvent Polyamide Resin ALFA08
This polyamide resin is an alcohol-soluble/co-solvent type resin with excellent solvent release and blocking properties.
Co Solvent Polyamide Resin ALFA09
Co-solvent polyamide resins are soluble in alcohol mixtures or mixtures of alcohols and aliphatic hydrocarbon co-solvents.
Co Solvent Polyamide Resin ALFA10
Co-solvent polyamide resins are soluble in alcohol mixtures or mixtures of alcohols and aliphatic hydrocarbon co-solvents.
Co Solvent Polyamide Resin ALFA11
Co-solvent polyamide resins are soluble in alcohol mixtures or mixtures of alcohols and aliphatic hydrocarbon co-solvents.
Co Solvent Polyamide Resin ALFA12
Co-solvent polyamide resins are soluble in alcohol mixtures or mixtures of alcohols and aliphatic hydrocarbon co-solvents.
Co Solvent Polyamide Resin ALFA13
The polyamide resin is a co-solvent resin that is soluble in alcohols, but usually requires a mixture of aliphatic hydrocarbons and alcohols to achieve gel stability. The polyamide resin provides fast solvent release and good oil resistance in flexographic/gravure inks on plastic substrates and is particularly effective as an overprint lacquer.
Co Solvent Polyamide Resin ALFA14
The polyamide resin is a co-solvent resin that is soluble in alcohols, but usually requires a mixture of aliphatic hydrocarbons and alcohols to achieve gel stability.
Co Solvent Polyamide Resin ALFA15
Brown beads shape.
Costunolide
Costunolide. Group: Biochemicals. Grades: Purified. CAS No. 553-21-9. Pack Sizes: 1mg, 10mg. US Biological Life Sciences.
Worldwide
Costunolide
Costunolide, a natural sesquiterpene compound with multiple biological activities, inhibits FPTase with IC50 of 20 μM, and also inhibits telomerase with IC50 of 65-90 μM. Uses: Anti-inflammatory and anti-oxidant. Synonyms: CCRIS 6754; NSC 106404; CCRIS6754; NSC106404; CCRIS-6754; NSC-106404. Grade: >98%. CAS No. 553-21-9. Molecular formula: C15H20O2. Mole weight: 232.32.
Costunolide
Costunolide ((+)-Costunolide) is a naturally occurring sesquiterpene lactone, with antioxidative, anti-inflammatory, antiallergic, bone remodeling, neuroprotective, hair growth promoting, anticancer, and antidiabetic properties. Costunolide can induce cell cycle arrest and apoptosis on breast cancer cells[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-Costunolide; Costus lactone. CAS No. 553-21-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0036.
Costunolide
100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H20O2. CAS No. 553-21-9. Prepack ID 32795028-100mg. Molecular Weight 232.32. See USA prepack pricing.
costunolide synthase
A heme-thiolate protein (P-450). The enzyme hydroxylates carbon C-6 of germacra-1(10),4,11(13)-trien-12-oate to give 6α-hydroxygermacra-1(10),4,11(13)-trien-12-oate, which probably spontaneously cyclises to form the lactone ring. Group: Enzymes. Enzyme Commission Number: EC 1.14.13.120. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0721; costunolide synthase; EC 1.14.13.120. Cat No: EXWM-0721.
Cosyntropin is an analogue of adrenocorticotrophic hormone (ACTH). It can stimulate the release of corticosteroids such as cortisol from the adrenal gland. Synonyms: Tetracosactide; Tetracosactrin; ACTH (1-24), human; H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-OH. CAS No. 16960-16-0. Molecular formula: C136H210N40O31S. Mole weight: 2933.45.
Cotadutide
Cotadutide (MEDI 0382) is a subcutaneous GLP-1 and glucagon receptor dual agonist that can be used to treat type 2 diabetes. Synonyms: MEDI 0382. CAS No. 1686108-82-6. Molecular formula: C167H252N42O55. Mole weight: 3728.03.
Cotadutide
Cotadutide (MEDI0382) is a potent dual agonist of glucagon-like peptide-1 (GLP-1) and GCGR with EC50 values of 6.9 pM and 10.2 pM, respectively. Cotadutide exhibits ability to facilitate both weight loss and glycaemic control, and alleviate fibrosis. Cotadutide can be used in the research of obesity and type 2 diabetes (T2D)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MEDI0382. CAS No. 1686108-82-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2231.
Cotadutide acetate
Cotadutide acetate is the acetate form of Cotadutide. Cotadutide is a dual receptor agonist. Molecular formula: C169H256N42O57. Mole weight: 3788.14.
COTI-2
COTI-2, an anti-cancer agent with low toxicity, is an orally available third generation activator of p53 mutant forms. COTI-2 acts both by reactivating mutant p53 and inhibiting the PI3K/AKT/mTOR pathway. COTI-2 induces apoptosis in multiple human tumor cell lines. COTI-2 exhibits antitumor activity in HNSCC through p53-dependent and -independent mechanisms. COTI-2 converts mutant p53 to wild-type conformation[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1039455-84-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19896.
COTI-2
COTI-2 is an p53 gene activator and the PI3K/AKT/mTOR pathway inhibitor. COTI-2 induces apoptosis and suppresses proliferation of a wide variety of human cancer cell lines in vitro. Synonyms: COTI-2; COTI2; COTI 2. 2BTA1O65BR; ZINC114475331; CS-8156; CS 8156; CS8156; N-[(E)-6,7-dihydro-5H-quinolin-8-ylideneamino]-4-pyridin-2-ylpiperazine-1-carbothioamide. Grade: 99%. CAS No. 1039455-84-9. Molecular formula: C19H22N6S. Mole weight: 366.48.
COTI 219
COTI 219 is an oral small-molecule inhibitor of the KRAS mutant form, without affecting normal KRAS function. Synonyms: COTI-219; 4-Methyl-1-piperazinecarbothioic Acid 2-(9H-Cyclopenta[1,2-b:4,3-b']dipyridin-9-ylidene)hydrazide. CAS No. 1039455-85-0. Molecular formula: C17H18N6S. Mole weight: 338.43.