A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Coumarin Impurity 30. Uses: For analytical and research use. CAS No. 53518-14-2. Molecular formula: C12H10F3NO2. Mole weight: 257.21. Catalog: APB53518142.
Coumarin Impurity 31
Coumarin Impurity 31. Uses: For analytical and research use. CAS No. 53518-18-6. Molecular formula: C16H14F3NO2. Mole weight: 309.29. Catalog: APB53518186.
Coumarin Impurity 32
Coumarin Impurity 32. Uses: For analytical and research use. CAS No. 29197-94-2. Molecular formula: C11H10NNaO5S. Mole weight: 291.25. Catalog: APB29197942.
Coumarin Impurity 33
Coumarin Impurity 33. Uses: For analytical and research use. CAS No. 55804-70-1. Molecular formula: C13H12F3NO2. Mole weight: 271.24. Catalog: APB55804701.
Coumarin Impurity 34
Coumarin Impurity 34. Uses: For analytical and research use. CAS No. 55804-66-5. Molecular formula: C18H19NO4. Mole weight: 313.35. Catalog: APB55804665.
Coumarin Impurity 35
Coumarin Impurity 35. Uses: For analytical and research use. CAS No. 55804-67-6. Molecular formula: C17H17NO3. Mole weight: 283.33. Catalog: APB55804676.
Coumarin Impurity 36
Coumarin Impurity 36. Uses: For analytical and research use. CAS No. 55804-68-7. Molecular formula: C16H14N2O2. Mole weight: 266.3. Catalog: APB55804687.
Coumarin Impurity 37
Coumarin Impurity 37. Uses: For analytical and research use. CAS No. 62669-75-4. Molecular formula: C20H23NO4. Mole weight: 341.41. Catalog: APB62669754.
Coumarin Impurity 38
Coumarin Impurity 38. Uses: For analytical and research use. CAS No. 55804-65-4. Molecular formula: C16H15NO4. Mole weight: 285.3. Catalog: APB55804654.
Coumarin Impurity 39
Coumarin Impurity 39. Uses: For analytical and research use. CAS No. 20571-42-0. Molecular formula: C13H15NO2. Mole weight: 217.27. Catalog: APB20571420.
Coumarin Impurity 4
Coumarin Impurity 4. Uses: For analytical and research use. CAS No. 38215-36-0. Molecular formula: C20H18N2O2S. Mole weight: 350.44. Catalog: APB38215360.
Coumarin Impurity 40
Coumarin Impurity 40. Uses: For analytical and research use. CAS No. 41175-45-5. Molecular formula: C18H19NO2. Mole weight: 281.36. Catalog: APB41175455.
Coumarin Impurity 41
Coumarin Impurity 41. Uses: For analytical and research use. CAS No. 87331-48-4. Molecular formula: C16H17NO4S. Mole weight: 319.38. Catalog: APB87331484.
Coumarin Impurity 42
Coumarin Impurity 42. Uses: For analytical and research use. CAS No. 113869-06-0. Molecular formula: C22H27NO4. Mole weight: 369.46. Catalog: APB113869060.
Coumarin Impurity 43
Coumarin Impurity 43. Uses: For analytical and research use. CAS No. 87349-92-6. Molecular formula: C20H18N2O2. Mole weight: 318.38. Catalog: APB87349926.
Coumarin Impurity 44
Coumarin Impurity 44. Uses: For analytical and research use. CAS No. 114768-72-8. Molecular formula: C21H25NO3. Mole weight: 339.44. Catalog: APB114768728.
Coumarin Impurity 45
Coumarin Impurity 45. Uses: For analytical and research use. CAS No. 87331-47-3. Molecular formula: C22H18N2O3. Mole weight: 358.4. Catalog: APB87331473.
Coumarin Impurity 46
Coumarin Impurity 46. Uses: For analytical and research use. CAS No. 85642-11-1. Molecular formula: C22H18N2O2S. Mole weight: 374.46. Catalog: APB85642111.
Coumarin Impurity 47
Coumarin Impurity 47. Uses: For analytical and research use. CAS No. 155306-71-1. Molecular formula: C26H26N2O2S. Mole weight: 430.57. Catalog: APB155306711.
Coumarin Impurity 48
Coumarin Impurity 48. Uses: For analytical and research use. CAS No. 1260635-77-5. Molecular formula: C18H22N2O5. Mole weight: 346.38. Catalog: APB1260635775.
Coumarin Impurity 49
Coumarin Impurity 49. Uses: For analytical and research use. CAS No. 201847-52-1. Molecular formula: C15H15F3N2O5. Mole weight: 360.29. Catalog: APB201847521.
Coumarin Impurity 5
Coumarin Impurity 5. Uses: For analytical and research use. CAS No. 58336-35-9. Molecular formula: C15H15NO2. Mole weight: 241.29. Catalog: APB58336359.
Coumarin Impurity 50
Coumarin Impurity 50. Uses: For analytical and research use. CAS No. 1056693-13-0. Molecular formula: C30H23NO4. Mole weight: 461.52. Catalog: APB1056693130.
Coumarin Impurity 51
Coumarin Impurity 51. Uses: For analytical and research use. CAS No. 2199-90-8. Molecular formula: C12H9BrO4. Mole weight: 297.1. Catalog: APB2199908.
Coumarin Impurity 52
Coumarin Impurity 52. Uses: For analytical and research use. CAS No. 1084-45-3. Molecular formula: C12H10O5. Mole weight: 234.21. Catalog: APB1084453.
Coumarin Impurity 53
Coumarin Impurity 53. Uses: For analytical and research use. CAS No. 1187744-84-8. Molecular formula: C28H23NO7. Mole weight: 485.49. Catalog: APB1187744848.
Coumarin Impurity 54
Coumarin Impurity 54. Uses: For analytical and research use. CAS No. 524698-40-6. Molecular formula: C28H23NO7. Mole weight: 485.49. Catalog: APB524698406.
Coumarin Impurity 55
Coumarin Impurity 55. Uses: For analytical and research use. CAS No. 957311-37-4. Molecular formula: C30H26N2O7. Mole weight: 526.55. Catalog: APB957311374.
Coumarin Impurity 6
Coumarin Impurity 6. Uses: For analytical and research use. CAS No. 27425-55-4. Molecular formula: C20H19N3O2. Mole weight: 333.39. Catalog: APB27425554.
Coumarin Impurity 7
Coumarin Impurity 7. Uses: For analytical and research use. CAS No. 1786-05-6. Molecular formula: C15H10O3. Mole weight: 238.24. Catalog: APB1786056.
Coumarin Impurity 8
Coumarin Impurity 8. Uses: For analytical and research use. CAS No. 531-59-9. Molecular formula: C10H8O3. Mole weight: 176.17. Catalog: APB531599.
Coumarin Impurity 9
Coumarin Impurity 9. Uses: For analytical and research use. CAS No. 6093-67-0. Molecular formula: C9H6O3. Mole weight: 162.14. Catalog: APB6093670.
Coumatetralyl. Group: Biochemicals. Alternative Names: 4-Hydroxy-3-(1,2,3,4-tetrahydro-1-naphthalenyl)-2H-1-benzopyran-2-one; 4-Hydroxy-3-(1,2,3,4-tetrahydro-1-naphthyl)coumarin; 3-(1,2,3,4-Tetrahydro-1-naphthyl)-4-hydroxycoumarin. Grades: Highly Purified. CAS No. 5836-29-3. Pack Sizes: 100mg, 250mg, 500mg, 1g. Molecular Formula: C19H16O3. US Biological Life Sciences.
Worldwide
Coumberol
Coumberol is a fluorescent substrate of AKR1C3 protein. Coumberol can be used for the research of AKR1C3[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 878019-53-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1342.
Coumberone
Coumberone is a metabolic fluorogenic probe, and isoform-selective substrate for all AKR1C isoforms. Coumberone can be reduced by all four members of the AKR1C family to its fluorescent alcohol coumberol. Coumberone can be used for the research of AKR1C[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 878019-47-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1341.
Coumermycin a1
Coumemycin A1 is found to bind at a second ATP-binding site in the C-terminal domain of Hsp90, IC50 70 μmol/L. It is produced by the strain of Streptomyces rishirensis, Str. spinichromogene and Str. Spinicoumarensis. It has anti-gram positive bacteria, negative bacteria, mycobacterium (weak) activity, cross-resistance with Novobiocin. Uses: Topoisomerase ii inhibitors. Synonyms: coumermycin a1; COUMERMYCIN; 4434-05-3; Coumamycin; Coumamycine; Coumamycinum; Cumamicina; Sugordomycin D-1a; Coumamycin [INN]; Notomycin; Coumermycin (USAN); Coumermycin [USAN]; Notomycin A1; PCH9QZ1IIH; CHEMBL4555272; NSC 107412; C05073; D02333; Sugordomycin D-la; [(3R,4S,5R,6R)-5-hydroxy-6-[4-hydroxy-3-[[5-[[4-hydroxy-7-[(2R,3R,4S,5R)-3-hydroxy-5-methoxy-6,6-dimethyl-4-(5-methyl-1H-pyrrole-2-ca. Grade: >98%. CAS No. 4434-5-3. Molecular formula: C55H59N5O20. Mole weight: 1110.08.
Coumermycin A1
Coumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria. Coumermycin A1 shows anti-orthopoxvirus activity. Uses: Scientific research. Category: Signaling pathways. CAS No. 4434-5-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N7452.
Coumestrol
Coumestrol. Group: Biochemicals. Alternative Names: 3,9-Dihydroxy-6H-benzofuro[3,2-c]-[1]benzopyran-6-one; 2-(2,4-Dihydroxyphenyl)-6-hydroxy-3-benzofurancarboxylic acid δ-lactone. Grades: Highly Purified. CAS No. 479-13-0. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C15H8O5. US Biological Life Sciences.
Worldwide
Coumestrol
Coumestrol, a phytoestrogen present in soybean products, exhibits activities against cancers, neurological disorders, and autoimmune diseases. It suppresses proliferation of ES2 cells with an IC50 of 50 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 479-13-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2335.
Coumurrayin
Coumurrayin is isolated from the herbs of Murraya paniculata (L.) Jack. Synonyms: 5,7-Dimethoxy-8-(3-methyl-2-butenyl)-2H-1-benzopyran-2-one; 5,7-Dimethoxy-8-(3-methyl-2-butenyl)coumarin. Grade: 97%. CAS No. 17245-25-9. Molecular formula: C16H18O4. Mole weight: 274.3.
Covalent Inhibitor Library
A unique collection of 941 covalent Inhibitors and other molecules with common warheads like chloroacetyl?2-Chloropropionyl?Acryloyl?sulfonyl fluoride, alkyne?acrylamide, ketocarbonyl?disulfide bond, etc. - Structurally diverse with some covalent inhibitors approved by the FDA- Detailed compound information with structure, target, IC50, and biological activity description- NMR and HPLC/LCMS validated to ensure high purity. Uses: Scientific use. Product Category: L9410. Categories: Covalent Inhibitor Libraries.
Covalent Natural Product Library
Detialed biological information and pharmacological information of the products, providing theoretical direction and research basis for screening. - Clear source: a selection of known active natural products from animals, plants and microorganisms; specific to plant species, and labeled with accurate English and Latin names that facilitates later verification in your research. - Comprehensive information: Detailed descriptions from compound structure to solubility, from signaling pathways and targets to biological activity information. - Cost-effective: eliminates expensive natural products with poor drug-forming properties, allowing you to get more high-quality natural products at a lower cost. - Highly customizable with free combination according to natural product source, natural product category, research area, drug market status, etc. Uses: Scientific use. Product Category: L6150. Categories: Covalent Natural Product Libraries.
CovidyteTM ED450
CovidyteTM ED450, a peptide substrate, can be cleaved by coronavirus proteases. The dark-FRET peptide contains Dabcyl (quencher) at the N-terminus and Edans (donor) at the C-terminus, respectively, and the fluorescence of Edans is effectively quenched by Dabcyl when the peptide is intact. When it is hydrolyzed by the coronavirus protease, the fluorescence of the Edans fragment is significantly enhanced because its fluorescence is no longer quenched by Dabcyl. Edans fluorescence intensity can effectively monitor the activity of coronavirus protease. It is a handy tool for screening coronavirus protease inhibitors. (excitation at 336, emission at 455 nm). Synonyms: EDANS-Val-Asn-Ser-Thr-Leu-Gln-Ser-Gly-Leu-Arg-Lys(DABCYL)-Met-OH. Molecular formula: C82H125N23O22S2. Mole weight: 1849.14.
CovidyteTM EN450
CovidyteTM EN450, a peptide substrate, can be cleaved by coronavirus proteases. The dark-FRET peptide contains Dabcyl (quencher) at the N-terminus and Edans (donor) at the C-terminus, respectively, and the fluorescence of Edans is effectively quenched by Dabcyl when the peptide is intact. When it is hydrolyzed by the coronavirus protease, the fluorescence of the Edans fragment is significantly enhanced because its fluorescence is no longer quenched by Dabcyl. Edans fluorescence intensity can effectively monitor the activity of coronavirus protease. It is a handy tool for screening coronavirus protease inhibitors. (excitation at 350, emission at 460 nm). Synonyms: H-Lys(DABCYL)-Thr-Ser-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg-Lys-Met-Glu-EDANS. Molecular formula: C95H141N25O24S2. Mole weight: 2081.42.
CovidyteTM IF670
CovidyteTM IF670, a peptide substrate, can be cleaved by coronavirus proteases. The dark-FRET peptide contains Tide QuencherTM 5 (TQ5) as a quencher at the N-terminal and iFluorTM 670 as a fluorescent donor at the C-terminal, respectively. When the peptide is intact, the fluorescence of iFluorTM 670 is effectively quenched by TQ5. When the peptide is hydrolyzed by the coronavirus proteases, the fluorescence of the iFluorTM 670 fragment is no longer quenched by TQ5, and the fluorescence is significantly enhanced. The fluorescence intensity of iFluorTM 670 can be used to effectively monitor the activity of coronavirus proteases. It is a powerful high-throughput screening tool for searching inhibitors of coronavirus protease. Compared to commonly used EDANS substrates, such as CovidyteTM ED450, the iFluorTM 670 substrate has stronger and longer fluorescence and is less disturbed by colored compounds that often cause false positive hits. (excitation at 656, emission at 670 nm). Synonyms: H-Cys(iFluor 647)-Val-Asn-Ser-Thr-Leu-Gln-Ser-Gly-Leu-Arg-Lys(TQ5)-Met-OH. Molecular formula: C58H105N19O19S2 + dye. Mole weight: 3068.
CovidyteTM TF670
CovidyteTM TF670, a peptide substrate, can be cleaved by coronavirus proteases. The dark-FRET peptide contains Tide QuencherTM 5 (TQ5) as a quencher at the N-terminal and Tide FluorTM 5 (TF5) as a fluorescence donor at the C-terminal, respectively. When the peptide is intact, the fluorescence of TF5 is effectively quenched by TQ5. When the peptide is hydrolyzed by the coronavirus proteases, the fluorescence of the TF5 fragment is no longer quenched by TQ5, and the fluorescence is significantly enhanced. The fluorescence intensity of TF5 can be used to effectively monitor the activity of coronavirus proteases. It is a powerful high-throughput screening tool for searching inhibitors of coronavirus protease. TQ5-TF5 pair has proved to be an extremely effective FRET pair for the development of FRET protease substrates. Compared to commonly used EDANS substrates, such as CovidyteTM EN450, the TF670 substrate has stronger, longer fluorescence and is less disturbed by colored compounds that often cause false positive hits. (excitation at 640, emission at 680 nm). Synonyms: H-Lys(TQ5)-Thr-Ser-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg-Lys-Met-Glu-Cys(TF5)-OH. Molecular formula: C71H121N21O22S2 + dye. Mole weight: 3620.
Cowaxanthone B
Cowaxanthone B. Group: Biochemicals. Alternative Names: 1,3-Dihydroxy-6,7-dimethoxy-2,8-diprenylxanthone. Grades: Plant Grade. CAS No. 212842-64-3. Pack Sizes: 10mg. Molecular Formula: C25H28O6, Molecular Weight: 424.486. US Biological Life Sciences.
A potent and slective COX-2 inhibitor(IC50= 3.9 μM). Synonyms: 1-(4-Sulfamylphenyl)-3-trifluoromethyl-5-(7-chloroindol-3-yl)-2-pyrazoline; 4-[3-(7-chloro-1H-indol-3-yl)-5-(trifluoromethyl)-3,4-dihydropyrazol-2-yl]benzenesulfonamide. CAS No. 787623-48-7. Molecular formula: C18H14ClF3N4O2S. Mole weight: 442.84.
COX-2-IN-2
COX2-IN-1 is a selective and inducible COX2 inhibitor (IC50= 0.24 μM) with anti-inflammatory and analgesic activities. Synonyms: 1-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)pyrazole-3-carbonitrile. CAS No. 134729-13-8. Molecular formula: C17H12FN3O2S. Mole weight: 341.36.
COX-2-IN-6
COX-2-IN-6, a gut-restricted selective COX-2 inhibitor, is used for chemoprevention of colorectal cancer. CAS No. 2756347-91-6. Molecular formula: C20H27NO6S. Mole weight: 409.50.
COX-2 Inhibitor I
An inhibitor of COX-2. Synonyms: Methyl [5-methylsulfonyl-1-(4-chlorobenzyl)-1H-2-indolyl]carboxylate; LM-1685; LM 1685; LM1685. CAS No. 416901-58-1. Molecular formula: C18H16ClNO4S. Mole weight: 377.8.
COX-2 Inhibitor II
A selective inhibitor of COX-2. Synonyms: SC-791; IN1371; 181696-33-3; 4-[(5-Difluoromethyl-3-phenyl)-4-isoxazolyl]benzenesulfonamide; SCHEMBL214781. CAS No. 181696-33-3. Molecular formula: C16H12F2N2O3S. Mole weight: 350.34.
COX-2 Inhibitor V, FK3311
COX-2 Inhibitor V, FK3311 is a selective Cox-2 inhibitor and NSAID. Group: Biochemicals. Grades: Highly Purified. CAS No. 116686-15-8. Pack Sizes: 5mg, 10mg. Molecular Formula: C15H13F2NO4S, Molecular Weight: 341.33. US Biological Life Sciences.
Worldwide
COX/5-LO-IN-1
A dual inhibitor of cylooxygenase and 5-lipoxygenase. Synonyms: Urea, N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl-2-propyn-1-yl]-N-hydroxy-; 1-[4-[5-[(4-fluorophenyl)methyl]thiophen-2-yl]but-3-yn-2-yl]-1-hydroxyurea. CAS No. 154355-75-6. Molecular formula: C16H15FN2O2S. Mole weight: 318.37.
COX IV Antibody [A4F21]. Group: Antibodies. Alternative Names: Cytochrome c oxidase subunit 4 isoform 1; mitochondrial; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1; COX4I1; COX4. Pack Sizes: 20uL. Product ID: F4133. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years.
United States; Europe
CoxZn1-xFe2O4
CoxZn1-xFe2O4. Purity: 99.5%.
cp028
cp028 is a potent pre-mRNA splicing inhibitor. cp028 inhibits splicing in HeLa nuclear extract with an IC50 value of 54 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 347397-83-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136951.
CP-?060
CP-060 is a novel type of Ca(2+) antagonist possessing both Ca(2+) overload inhibition, with antioxidant and cardioprotective activities. Synonyms: CP-060; CP060; CP 060; 3-[3-[2-(1,3-benzodioxol-5-yloxy)ethyl-methylamino]propyl]-2-(3,5-ditert-butyl-4-hydroxyphenyl)-1,3-thiazolidin-4-one. CAS No. 180090-15-7. Molecular formula: C30H42N2O5S. Mole weight: 542.73.
CP-10
CP-10 is a PROTAC connected by ligands for Cereblon and CDK, with highly selective, specific, and remarkable CDK6 degradation (DC50=2.1 nM). It inhibits proliferation of several haematopoietic cancer cells with impressive potency including multiple myeloma, and can still degrades mutated and overexpressed CDK6[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2366268-80-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-125835.
CP 100356
CP 100356 is a high affinity P-glycoprotein inhibitor.Ki value is 58 nM for mouse Pgp1a and 94nMfor Pgp1b isoforms. It can Inhibit calcein-AM uptake in MDR1-transfected MDCKII cells with IC50 value of 0.5 μM and prazosin transport in BCRP-transfected MDCKII cells with IC50 value of 1.5 μM. Preclinical development for Cancer in USA was discontinued. Uses: Cancer. Synonyms: CP 100356; CP100356; CP-100356; 4-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-(2-(3,4-dimethoxyphenyl)ethyl)-6,7-dimethoxy-2-Quinazolinamine; 142715-48-8(hydrochloride). Grade: >98 %. CAS No. 142716-85-6. Molecular formula: C31H36N4O6. Mole weight: 560.64.
The hydrochloride salt form of CP-100356, which has been found to be an inhibitor of MDR1 (P-Gp) and show inactive in inhibiting multidrug resistance-associated protein 2 (MPR2). Synonyms: CP 100356 hydrochloride; CP100356 hydrochloride; CP-100356 hydrochloride; 4-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-2[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxy-2-quinazolinamine hydrochloride. Grade: ≥98% by HPLC. CAS No. 142715-48-8. Molecular formula: C31H36N4O6.HCl. Mole weight: 597.10.
CP-100356 hydrochloride
CP-100356 hydrochloride is an orally active dual MDR1 (P-gp)/BCRP inhibitor, with an IC50s of 0.5 and 1.5 μM for inhibiting MDR1-mediated Calcein-AM transport and BCRP-mediated Prazosin transport, respectively. CP-100356 hydrochloride is also a weak inhibitor of OATP1B1 (IC50=?66 μM). CP-100356 hydrochloride is devoid of inhibition against MRP2 and major human P450 enzymes (IC50>15 μM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 142715-48-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108347.