A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Coumestrol, a phytoestrogen present in soybean products, exhibits activities against cancers, neurological disorders, and autoimmune diseases. It suppresses proliferation of ES2 cells with an IC50 of 50 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 479-13-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2335.
Coumestrol
Coumestrol. Group: Biochemicals. Alternative Names: 3,9-Dihydroxy-6H-benzofuro[3,2-c]-[1]benzopyran-6-one; 2-(2,4-Dihydroxyphenyl)-6-hydroxy-3-benzofurancarboxylic acid δ-lactone. Grades: Highly Purified. CAS No. 479-13-0. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C15H8O5. US Biological Life Sciences.
Worldwide
Coumurrayin
Coumurrayin is isolated from the herbs of Murraya paniculata (L.) Jack. Synonyms: 5,7-Dimethoxy-8-(3-methyl-2-butenyl)-2H-1-benzopyran-2-one; 5,7-Dimethoxy-8-(3-methyl-2-butenyl)coumarin. Grade: 97%. CAS No. 17245-25-9. Molecular formula: C16H18O4. Mole weight: 274.3.
Covalent Inhibitor Library
A unique collection of 941 covalent Inhibitors and other molecules with common warheads like chloroacetyl?2-Chloropropionyl?Acryloyl?sulfonyl fluoride, alkyne?acrylamide, ketocarbonyl?disulfide bond, etc. - Structurally diverse with some covalent inhibitors approved by the FDA- Detailed compound information with structure, target, IC50, and biological activity description- NMR and HPLC/LCMS validated to ensure high purity. Uses: Scientific use. Product Category: L9410. Categories: Covalent Inhibitor Libraries.
Covalent Natural Product Library
Detialed biological information and pharmacological information of the products, providing theoretical direction and research basis for screening. - Clear source: a selection of known active natural products from animals, plants and microorganisms; specific to plant species, and labeled with accurate English and Latin names that facilitates later verification in your research. - Comprehensive information: Detailed descriptions from compound structure to solubility, from signaling pathways and targets to biological activity information. - Cost-effective: eliminates expensive natural products with poor drug-forming properties, allowing you to get more high-quality natural products at a lower cost. - Highly customizable with free combination according to natural product source, natural product category, research area, drug market status, etc. Uses: Scientific use. Product Category: L6150. Categories: Covalent Natural Product Libraries.
CovidyteTM ED450
CovidyteTM ED450, a peptide substrate, can be cleaved by coronavirus proteases. The dark-FRET peptide contains Dabcyl (quencher) at the N-terminus and Edans (donor) at the C-terminus, respectively, and the fluorescence of Edans is effectively quenched by Dabcyl when the peptide is intact. When it is hydrolyzed by the coronavirus protease, the fluorescence of the Edans fragment is significantly enhanced because its fluorescence is no longer quenched by Dabcyl. Edans fluorescence intensity can effectively monitor the activity of coronavirus protease. It is a handy tool for screening coronavirus protease inhibitors. (excitation at 336, emission at 455 nm). Synonyms: EDANS-Val-Asn-Ser-Thr-Leu-Gln-Ser-Gly-Leu-Arg-Lys(DABCYL)-Met-OH. Molecular formula: C82H125N23O22S2. Mole weight: 1849.14.
CovidyteTM EN450
CovidyteTM EN450, a peptide substrate, can be cleaved by coronavirus proteases. The dark-FRET peptide contains Dabcyl (quencher) at the N-terminus and Edans (donor) at the C-terminus, respectively, and the fluorescence of Edans is effectively quenched by Dabcyl when the peptide is intact. When it is hydrolyzed by the coronavirus protease, the fluorescence of the Edans fragment is significantly enhanced because its fluorescence is no longer quenched by Dabcyl. Edans fluorescence intensity can effectively monitor the activity of coronavirus protease. It is a handy tool for screening coronavirus protease inhibitors. (excitation at 350, emission at 460 nm). Synonyms: H-Lys(DABCYL)-Thr-Ser-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg-Lys-Met-Glu-EDANS. Molecular formula: C95H141N25O24S2. Mole weight: 2081.42.
CovidyteTM IF670
CovidyteTM IF670, a peptide substrate, can be cleaved by coronavirus proteases. The dark-FRET peptide contains Tide QuencherTM 5 (TQ5) as a quencher at the N-terminal and iFluorTM 670 as a fluorescent donor at the C-terminal, respectively. When the peptide is intact, the fluorescence of iFluorTM 670 is effectively quenched by TQ5. When the peptide is hydrolyzed by the coronavirus proteases, the fluorescence of the iFluorTM 670 fragment is no longer quenched by TQ5, and the fluorescence is significantly enhanced. The fluorescence intensity of iFluorTM 670 can be used to effectively monitor the activity of coronavirus proteases. It is a powerful high-throughput screening tool for searching inhibitors of coronavirus protease. Compared to commonly used EDANS substrates, such as CovidyteTM ED450, the iFluorTM 670 substrate has stronger and longer fluorescence and is less disturbed by colored compounds that often cause false positive hits. (excitation at 656, emission at 670 nm). Synonyms: H-Cys(iFluor 647)-Val-Asn-Ser-Thr-Leu-Gln-Ser-Gly-Leu-Arg-Lys(TQ5)-Met-OH. Molecular formula: C58H105N19O19S2 + dye. Mole weight: 3068.
CovidyteTM TF670
CovidyteTM TF670, a peptide substrate, can be cleaved by coronavirus proteases. The dark-FRET peptide contains Tide QuencherTM 5 (TQ5) as a quencher at the N-terminal and Tide FluorTM 5 (TF5) as a fluorescence donor at the C-terminal, respectively. When the peptide is intact, the fluorescence of TF5 is effectively quenched by TQ5. When the peptide is hydrolyzed by the coronavirus proteases, the fluorescence of the TF5 fragment is no longer quenched by TQ5, and the fluorescence is significantly enhanced. The fluorescence intensity of TF5 can be used to effectively monitor the activity of coronavirus proteases. It is a powerful high-throughput screening tool for searching inhibitors of coronavirus protease. TQ5-TF5 pair has proved to be an extremely effective FRET pair for the development of FRET protease substrates. Compared to commonly used EDANS substrates, such as CovidyteTM EN450, the TF670 substrate has stronger, longer fluorescence and is less disturbed by colored compounds that often cause false positive hits. (excitation at 640, emission at 680 nm). Synonyms: H-Lys(TQ5)-Thr-Ser-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg-Lys-Met-Glu-Cys(TF5)-OH. Molecular formula: C71H121N21O22S2 + dye. Mole weight: 3620.
Cowaxanthone B
Cowaxanthone B. Group: Biochemicals. Alternative Names: 1,3-Dihydroxy-6,7-dimethoxy-2,8-diprenylxanthone. Grades: Plant Grade. CAS No. 212842-64-3. Pack Sizes: 10mg. Molecular Formula: C25H28O6, Molecular Weight: 424.486. US Biological Life Sciences.
A potent and slective COX-2 inhibitor(IC50= 3.9 μM). Synonyms: 1-(4-Sulfamylphenyl)-3-trifluoromethyl-5-(7-chloroindol-3-yl)-2-pyrazoline; 4-[3-(7-chloro-1H-indol-3-yl)-5-(trifluoromethyl)-3,4-dihydropyrazol-2-yl]benzenesulfonamide. CAS No. 787623-48-7. Molecular formula: C18H14ClF3N4O2S. Mole weight: 442.84.
COX-2-IN-2
COX2-IN-1 is a selective and inducible COX2 inhibitor (IC50= 0.24 μM) with anti-inflammatory and analgesic activities. Synonyms: 1-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)pyrazole-3-carbonitrile. CAS No. 134729-13-8. Molecular formula: C17H12FN3O2S. Mole weight: 341.36.
COX-2-IN-6
COX-2-IN-6, a gut-restricted selective COX-2 inhibitor, is used for chemoprevention of colorectal cancer. CAS No. 2756347-91-6. Molecular formula: C20H27NO6S. Mole weight: 409.50.
COX-2 Inhibitor I
An inhibitor of COX-2. Synonyms: Methyl [5-methylsulfonyl-1-(4-chlorobenzyl)-1H-2-indolyl]carboxylate; LM-1685; LM 1685; LM1685. CAS No. 416901-58-1. Molecular formula: C18H16ClNO4S. Mole weight: 377.8.
COX-2 Inhibitor II
A selective inhibitor of COX-2. Synonyms: SC-791; IN1371; 181696-33-3; 4-[(5-Difluoromethyl-3-phenyl)-4-isoxazolyl]benzenesulfonamide; SCHEMBL214781. CAS No. 181696-33-3. Molecular formula: C16H12F2N2O3S. Mole weight: 350.34.
COX-2 Inhibitor V, FK3311
COX-2 Inhibitor V, FK3311 is a selective Cox-2 inhibitor and NSAID. Group: Biochemicals. Grades: Highly Purified. CAS No. 116686-15-8. Pack Sizes: 5mg, 10mg. Molecular Formula: C15H13F2NO4S, Molecular Weight: 341.33. US Biological Life Sciences.
Worldwide
COX/5-LO-IN-1
A dual inhibitor of cylooxygenase and 5-lipoxygenase. Synonyms: Urea, N-[3-[5-[(4-fluorophenyl)methyl]-2-thienyl]-1-methyl-2-propyn-1-yl]-N-hydroxy-; 1-[4-[5-[(4-fluorophenyl)methyl]thiophen-2-yl]but-3-yn-2-yl]-1-hydroxyurea. CAS No. 154355-75-6. Molecular formula: C16H15FN2O2S. Mole weight: 318.37.
COX IV Antibody [A4F21]. Group: Antibodies. Alternative Names: Cytochrome c oxidase subunit 4 isoform 1; mitochondrial; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1; COX4I1; COX4. Pack Sizes: 20uL. Product ID: F4133. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years.
United States; Europe
CoxZn1-xFe2O4
CoxZn1-xFe2O4. Purity: 99.5%.
cp028
cp028 is a potent pre-mRNA splicing inhibitor. cp028 inhibits splicing in HeLa nuclear extract with an IC50 value of 54 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 347397-83-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136951.
CP-?060
CP-060 is a novel type of Ca(2+) antagonist possessing both Ca(2+) overload inhibition, with antioxidant and cardioprotective activities. Synonyms: CP-060; CP060; CP 060; 3-[3-[2-(1,3-benzodioxol-5-yloxy)ethyl-methylamino]propyl]-2-(3,5-ditert-butyl-4-hydroxyphenyl)-1,3-thiazolidin-4-one. CAS No. 180090-15-7. Molecular formula: C30H42N2O5S. Mole weight: 542.73.
CP-10
CP-10 is a PROTAC connected by ligands for Cereblon and CDK, with highly selective, specific, and remarkable CDK6 degradation (DC50=2.1 nM). It inhibits proliferation of several haematopoietic cancer cells with impressive potency including multiple myeloma, and can still degrades mutated and overexpressed CDK6[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2366268-80-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-125835.
CP 100356
CP 100356 is a high affinity P-glycoprotein inhibitor.Ki value is 58 nM for mouse Pgp1a and 94nMfor Pgp1b isoforms. It can Inhibit calcein-AM uptake in MDR1-transfected MDCKII cells with IC50 value of 0.5 μM and prazosin transport in BCRP-transfected MDCKII cells with IC50 value of 1.5 μM. Preclinical development for Cancer in USA was discontinued. Uses: Cancer. Synonyms: CP 100356; CP100356; CP-100356; 4-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-(2-(3,4-dimethoxyphenyl)ethyl)-6,7-dimethoxy-2-Quinazolinamine; 142715-48-8(hydrochloride). Grade: >98 %. CAS No. 142716-85-6. Molecular formula: C31H36N4O6. Mole weight: 560.64.
The hydrochloride salt form of CP-100356, which has been found to be an inhibitor of MDR1 (P-Gp) and show inactive in inhibiting multidrug resistance-associated protein 2 (MPR2). Synonyms: CP 100356 hydrochloride; CP100356 hydrochloride; CP-100356 hydrochloride; 4-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-2[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxy-2-quinazolinamine hydrochloride. Grade: ≥98% by HPLC. CAS No. 142715-48-8. Molecular formula: C31H36N4O6.HCl. Mole weight: 597.10.
CP-100356 hydrochloride
CP-100356 hydrochloride is an orally active dual MDR1 (P-gp)/BCRP inhibitor, with an IC50s of 0.5 and 1.5 μM for inhibiting MDR1-mediated Calcein-AM transport and BCRP-mediated Prazosin transport, respectively. CP-100356 hydrochloride is also a weak inhibitor of OATP1B1 (IC50=?66 μM). CP-100356 hydrochloride is devoid of inhibition against MRP2 and major human P450 enzymes (IC50>15 μM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 142715-48-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108347.
CP-100829, an indole derivative, could probably be useful in some biological studies. Synonyms: CP-100829; CP100829; CP 100829; UNII-X7Y3B8B649. X7Y3B8B649; 1H-Indole-1-carboxamide, 6-chloro-3-((4-chloro-2-thienyl)carbonyl)-5-fluoro-2,3-dihydro-2-oxo-; 1H-Indole-1-carboxamide, 6-chloro-3-((4-chloro-2-thienyl)hydroxymethylene)-5-fluoro-2,3-dihydro-2-oxo-, (Z)-. Grade: 98%. CAS No. 172618-05-2. Molecular formula: C14H7Cl2FN2O3S. Mole weight: 373.18.
CP 101606
CP 101606 is a potent and selective NR2B antagonist of N-Methyl-D-Aspartate (NMDA) glutamate receptors. It decreases pentylenetetrazol-induced seizures. Synonyms: CP-101606; CP 101606; CP101606; Traxoprodil; 1-((1S,2S)-1-hydroxy-1-(4-hydroxyphenyl)propan-2-yl)-4-phenylpiperidin-4-ol. Grade: 99%. CAS No. 134234-12-1. Molecular formula: C20H25NO3. Mole weight: 327.42.
CP-105696
CP-105696 is a potent and selective Leukotriene B4 Receptor antagonist, with an IC50 of 8.42 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pfizer 105696. CAS No. 158081-99-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19193.
CP-105696
CP-105696, a chromen derivative, has been found to be a leukotriene B4 receptor antagonist that was once studied against sorts of nflammatory disease. Uses: Leukotriene antagonists. Synonyms: CP-105696; UNII-Z7354TW4BM; CP-105,696; CHEMBL51770; CP 105696; Z7354TW4BM; 1-[(3S,4R)-4-hydroxy-3-[(4-phenylphenyl)methyl]-3,4-dihydro-2H-chromen-7-yl]cyclopentane-1-carboxylic acid. Grade: 98%. CAS No. 158081-99-3. Molecular formula: C28H28O4. Mole weight: 428.53.
CP-114271
CP-114271, a thiazole derivative, has been found to be a β3 adrenergic receptor agonist that was once studied in obesity therapy. Synonyms: CP-114271; CP 114271; CP114271; UL-TG 307; UL-TG-307; UNII-CY8W406YBX.; UL-TG 307; UL-TG-307; CY8W406YBX; Acetic acid, (4-((2R)-2-(((2S)-2-hydroxy-2-(2-(trifluoromethyl)-4-thiazolyl)ethyl)amino)propyl)phenoxy)-. Grade: 98%. CAS No. 162326-86-5. Molecular formula: C17H19F3N2O4S. Mole weight: 404.40.
CP 115953
CP 115953 is a Type II DNA topoisomerase inhibitor originated by Pfizer. CP 115953 inhibits topoisomerase II activity via an interaction with the enzyme and not by DNA unwinding. It can stimulate cytokine production by lymphocytes. Research for treatment of cancer was discontinued. Uses: Cancer. Synonyms: CP 115953; CP115953; CP-115953; 1-Cyclopropyl-6,8-difluoro-1,4-dihydro-7-(4-hydroxyphenyl)-4-oxo-3-quinolinecarboxylic acid. Grade: 98%. CAS No. 136440-70-5. Molecular formula: C19H13F2NO4. Mole weight: 357.31.
CP 117227
CP 117227, a dibenzocyclohepten derivative, has been found to be a Type II DNA topoisomerase inhibitor that was once developed in studies of anticancer. Synonyms: CP 117227; CP-117227; CP117227; 1-Piperazineethanol, 4-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-yl)-alpha-((5-quinolinyloxy)methyl)-, (S)-. Grade: 98%. CAS No. 154531-78-9. Molecular formula: C31H33N3O2. Mole weight: 479.61.
CP-120509
It is produced by the strain of Actinomadura roseorufa 263606. CP-120509 has anti-gram-positive bacteria, spirochete and spirochete activity, and also has a good anti-coccidiosis effect caused by Eimeria acervulina, E. tenella. Molecular formula: C45H76O17. Mole weight: 889.07.
CP-122721
CP-122721, a phenylpiperidin derivative, has been found to be a NK1 receptor antagonist that could probably be effective as antidepressant and antiemetic agent. The result of Phase II clinical trial for depression of it has not been reported yet since 2003. Synonyms: CP122721; CP 122721; 3-(2-methoxy-5-trifluoromethoxybenzyl)amino-2-piperidine. Grade: 98%. CAS No. 145742-28-5. Molecular formula: C20H23F3N2O2. Mole weight: 380.40.
CP 135807
CP 135807, an indole derivative, has been found to be a selective 5-HT1D receptor agonist. Synonyms: CP135807; CP-135807; 3-(N-Methylpyrrolidin-2-ylmethyl)-5-(3-nitropyrid-2-ylamino)-1H-indole; (R)-3-((1-Methyl-2-pyrrolidinyl)methyl)-N-(3-nitro-2-pyridinyl)-1H-indol-5-amine. Grade: ≥98% by HPLC. CAS No. 151272-90-1. Molecular formula: C19H21N5O2. Mole weight: 351.40.
CP-135807
A selective 5-HT1D receptor agonist. Group: Biochemicals. Alternative Names: 3-[[(2R)-1-Methyl-2-pyrrolidinyl]methyl]-N-(3-nitro-2-pyridinyl)-1H-indol-5-amine;(R)-3-[(1-Methyl-2-pyrrolidinyl)methyl]-N-(3-nitro-2-pyridinyl)-1H-indol-5-amine; CP 135807. Grades: Highly Purified. CAS No. 151272-90-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CP 141938
CP 141938 is a potent and selective neurokinin-1 (NK1) receptor antagonist with very different brain tendencies and potency in centrally mediated activity models. Synonyms: Methanesulfonamide, N-[4-methoxy-3-[[[(2R,3R)-2-phenyl-3-piperidinyl]amino]methyl]phenyl]-N-methyl-, rel-; Methanesulfonamide, N-[4-methoxy-3-[[(2-phenyl-3-piperidinyl)amino]methyl]phenyl]-N-methyl-, cis-; rel-N-[4-Methoxy-3-[[[(2R,3R)-2-phenyl-3-piperidinyl]amino]methyl]phenyl]-N-methylmethanesulfonamide; CP141938; CP-141938. Grade: ≥95%. CAS No. 182822-62-4. Molecular formula: C21H29N3O3S. Mole weight: 403.54.
CP-141938
CP-141938. Group: Biochemicals. Alternative Names: rel-N- [4-Methoxy-3- [ [ [ (2R, 3R) -2-phenyl-3-piperidinyl] amino] methyl] phenyl] -N-methyl-methanesulfonamide. Grades: Highly Purified. CAS No. 182822-62-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C21H29N3O3S. US Biological Life Sciences.
Worldwide
CP 154526
The hydrochloride salt form of CP-154526, which has been found to be a non-peptide CRF1 receptor antagonist and could exhibit anxiolytic-like activity at some extent. Synonyms: CP 154526; CP154526; CP-154526; N-Butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine hydrochloride. Grade: ≥99% by HPLC. CAS No. 257639-98-8. Molecular formula: C23H32N4.HCl. Mole weight: 400.99.
CP 154526 hydrochloride
CP 154526 hydrochloride is a potent, brain-penetrant and selective corticotropin-releasing factor receptor 1 (CRF1) antagonist with a Ki of 2.7 nM. CP 154526 hydrochloride shows selective for CRF1 over CRF2 (Ki = >10 μM). CP 154526 hydrochloride has anxiolytic activities[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 257639-98-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12129.
CP-195494
CP-195494, a benzothiazol derivative, was once studied as a leukotriene receptor antagonist. Synonyms: UNII-1D055URF6U; CHEMBL300701; CP195494; CP 195494; CP-195494; (+)-CP-195494; 1D055URF6U; BDBM50070919. Grade: 98%. CAS No. 158103-57-2. Molecular formula: C26H22F4N2O5S2. Mole weight: 582.59.
CP-195543
CP-195543 is a potent and selective leukotriene B4 antagonist developed as an oral treatment for for inflammatory diseases. Synonyms: 2-[(3S,4R)-3-benzyl-4-hydroxy-3,4-dihydro-2H-chromen-7-yl]-4-(trifluoromethyl)benzoic acid; 2-(3-benzyl-4-hydroxy-chroman-7-yl)-4-trifluoromethyl-benzoic acid; CP 195543; CP-195543; CP195543. Grade: >98%. CAS No. 204981-48-6. Molecular formula: C24H19F3O4. Mole weight: 428.4.
CP-199330
CP-199330, a chromen derivative, has been found to be a Leukotriene D4 receptor antagonist that was once studied against asthma by Pfizer. Synonyms: CP-199330; CP 199330; CP199330; UNII-V4WYK6T8QA; CHEMBL96206; V4WYK6T8QA; SCHEMBL8890632; BDBM50081532; N-[3-[[(3R,4R)-6-[(7-chloroquinolin-2-yl)methoxy]-4-hydroxy-3,4-dihydro-2H-chromen-3-yl]methyl]-4-methoxyphenyl]-1,1,1-trifluoromethanesulfonamide. Grade: 98%. CAS No. 158102-92-2. Molecular formula: C28H24ClF3N2O6S. Mole weight: 609.01.
CP-199330 Sodium
The sodium salt form of CP-199330 which is a chromen derivative and has been found to be a Leukotriene D4 receptor antagonist that was once studied against asthma by Pfizer. Synonyms: CP-199330 sodium; CP 199330 sodium; CP199330 sodium; CP-199330 monosodium salt; Methanesulfonamide, N-(3-((6-((7-chloro-2-quinolinyl)methoxy)-3,4-dihydro-4-hydroxy-2H-1-benzopyran-3-yl)methyl)-4-methoxyphenyl)-1,1,1-trifluoro-, monosodium salt, (3R-cis)-; UNII-74573Q728X component FZCWCSNK. Grade: 98%. CAS No. 158102-98-8. Molecular formula: C28H23ClF3N2NaO6S. Mole weight: 630.99.
CP2
CP2 is a cyclic peptide and it is an inhibitor of the JmjC histone demethylases KDM4 with IC50 values of 42 nM and 29 nM for KDM4A and KDM4C, respectively. Grade: ≥97%. Molecular formula: C92H120N24O26S. Mole weight: 2010.15.
CP21R7
CP21R7 is potent GSK-3β inhibitor, with an IC50 of 1.8 nM; CP21R7 also shows inhibitory activitiy against PKCα, with an IC50 of 1900 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CP21. CAS No. 125314-13-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100207.
CP21R7
CP21R7 is a potent and selective GSK3β inhibitor. It acts as an activator of stem cells prior to the induction of differentiation of stem cells to endothelial and smooth muscle cells. Uses: Cp21r7 is a selective gsk-3β inhibitor which could probably influence luciferase activity at some extent. Synonyms: 3-(3-aminophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione. Grade: >98%. CAS No. 125314-13-8. Molecular formula: C19H15N3O2. Mole weight: 317.34.
CP-220629
CP-220629, a Pyrazolopyridin derivative, has been found to be a Type 4 cyclic nucleotide phosphodiesterase inhibitor that was once studied as an anti-inflammatory as well as antiasthmatic agent. Synonyms: UNII-BAV9N49AFE; CP-220629; CP 220629; CP220629; BAV9N49AFE; SCHEMBL84865; CHEMBL75819; 1-cyclopentyl-3-ethyl-6-(2-methylphenyl)-4,5-dihydropyrazolo[3,4-c]pyridin-7-one. Grade: 98%. CAS No. 162141-96-0. Molecular formula: C20H25N3O. Mole weight: 323.44.
CP22185
CP22185 is a catecholamine-uptake inhibitor. Synonyms: CP-22185; CP 22185; Sertraline hydrochloride specified impurity B; (1RS,4RS)-N-Methyl-4-phenyl-1,2,3,4-tetrahydronaphthalen-1-amine; N-Methyl-4alpha-phenyltetralin-1alpha-amine. Grade: 98%. CAS No. 52758-03-9. Molecular formula: C17H19N. Mole weight: 237.34.
CP-225917
CP-225917 inhibits Ras farnesyl transferase from the mouse brain and Squalene synthase. Molecular formula: C31H38O10. Mole weight: 570.63.
CP 226269
CP 226269 is a selective dopamine D4 agonist. Synonyms: CP-226269; CP 226269; CP226269; 5-fluoro-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]-1H-indole. Grade: 99%. CAS No. 220941-93-5. Molecular formula: C18H19FN4. Mole weight: 310.37.
Cp-24879 hydrochloride
Cp-24879 hydrochloride. CAS No. 10141-51-2. Product ID: ACM10141512. Molecular formula: C11H18ClNO. Mole weight: 215.72. Alfa Chemistry - ISO 9001:32057 Certified.
CP 24,879 hydrochloride
CP 24,879 is an inhibitor of arachidonic acid biosynthesis by inhibition of Δ5/Δ6 desaturase. Synonyms: p-(Isopentyloxy)-aniline; 4-(3-methylbutoxy)-benzenamine monohydrochloride. Grade: ≥98%. CAS No. 10141-51-2. Molecular formula: C11H17NO·HCl. Mole weight: 215.8.
CP-24879 hydrochloride
CP-24879 (hydrochloride) is a potent, selective and combined delta5D/delta6D inhibitor. CP-24879 (hydrochloride) can significantly reduce intracellular lipid accumulation and inflammatory injury in hepatocytes. CP-24879 (hydrochloride) exhibits superior antisteatotic and anti-inflammatory actions in fat-1 and ω-3-treated hepatocytes, and can be used for non-alcoholic steatohepatitis research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 10141-51-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115319.
CP26
CP26 is a small molecule inhibitor of protein dislocation from the ER lumen to the cytosol. CP26 targets the Hrd1 complex, inhibits ERAD, and induces ER stress[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 500285-30-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-49116.
CP-263114
CP-263114 inhibits Ras farnesyl transferase from the mouse brain and Squalene synthase. CAS No. 186700-09-4. Molecular formula: C31H36O9. Mole weight: 552.61.
CP-283097
CP-283097 is NR2B N-Methyl-D-Aspartate receptor antagonist originated by Pfizer. Preclinical trials for the treatment of Migraine and Neurodegenerative disorders were discontinued. Uses: Migraine; neurodegenerative disorders. Synonyms: CP-283097; CP283097; CP 283097; UNII-WHL1Z3GN15; ; (3R,4S)-Rel-3,4-dihydro-3-(4-hydroxy-4-(phenylmethyl)-1-piperidinyl)-2H-1-benzopyran-4,7-diol. Grade: 98%. CAS No. 138047-56-0. Molecular formula: C21H25NO4. Mole weight: 355.43.
CP-28888
CP-28888, an interferon inducer, is more effective in mice, but less active in humans and lacks anti-rhinovirus effects. Synonyms: CP 28888-27; N,N-Dihexadecyl-1,3-benzenedi(methanamine); 1,3-Benzenedimethanamine, N1,N3-dihexadecyl-; N,N'-[1,3-Phenylenebis(methylene)]di(hexadecan-1-amine); N,N'-[1,3-Phenylenebis(methylene)]di(1-hexadecanamine). Grade: ≥95%. CAS No. 69938-75-6. Molecular formula: C40H76N2. Mole weight: 585.04.
CP-289
CP-289 is an effective C5a receptor antagonist with an IC50 of 1 μM. Grade: >98.0%. CAS No. 1349637-14-4. Molecular formula: C30H35ClN2O2. Mole weight: 491.07.
Cp2C / CppC
Cp2C is an omnipresent chemical compound extensively employed in the realm of biomedical industry, recognized for its profound efficacy in restraining the proliferation of cancerous cells, primarily manifested in breast and lung malignancies. Synonyms: P1, P2- Di- (cytidine- 5')- diphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 29789-88-6. Molecular formula: C18H26N6O15P2 (free acid). Mole weight: 628.4 (free acid).
CP2 (Nic)
CP2 (Nic) is an efficacious and discriminating allosteric modulator of the α7 nicotinic acetylcholine receptor (nAChR), and exhibits potential utility as a treatment for cognitive deficits linked with Alzheimer's disease. Synonyms: Nicotinamide cytosine dinucleotide, Sodium salt. Grade: ≥ 95% by HPLC. Molecular formula: C20H27N5O15P2 (free acid). Mole weight: 639.40 (free acid).
Cp2-SO4
Cp2-SO4, a phenylalanine derivative, reverses interleukin 4 induced 1 (IL4I1)-dependent inhibition of T-cell proliferation with Ki of 21.2 μM. Molecular formula: C14H23NO6S. Mole weight: 333.40.
CP-312
CP-312 is a potent Heme Oxygenase-1 (HO-1) inducer. CP-312 protects hiPSC-CM viability by targeting the antioxidant response network through induction of HMOX1 expression. CP-312 protects human iPSC-derived cardiomyocytes from oxidative stress[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 895470-67-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124815.
CP 31398
CP 31398 is a p53 stabilizer and could probably restrain the growth of small human tumor xenografts in vivo. CP 31398 is a prototype small molecule that stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53. Synonyms: 1,3-Propanediamine, N3-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-; 1,3-Propanediamine, N'-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-; N3-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-1,3-propanediamine; CP31398; CP-31398. Grade: ≥95%. CAS No. 259199-65-0. Molecular formula: C22H26N4O. Mole weight: 362.47.
CP 31398 dihydrochloride
CP 31398 is a p53 stabilizer and could probably restrain the growth of small human tumor xenografts in vivo. CP 31398 is a prototype small molecule that stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53. Synonyms: CP31398 dihydrochloride; CP-31398 dihydrochloride; N'-[2-[2-(4-Methoxyphenyl)ethenyl]-4-quinazolinyl]-N,N-dimethyl-1,3-propanediamine dihydrochloride; 1,3-Propanediamine, N3-[2-[2-(4-methoxyphenyl)ethenyl]-4-quinazolinyl]-N1,N1-dimethyl-, hydrochloride (1:2); PZ 0115; N1-(2-(4-methoxystyryl)quinazolin-4-yl)-N3,N3-dimethylpropane-1,3-diamine dihydrochloride. Grade: ≥99% by HPLC. CAS No. 1217195-61-3. Molecular formula: C22H26N4O.2HCl. Mole weight: 435.39.