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| Product | Description | |
|---|---|---|
| CP-96021 hydrochloride | CP-96021 hydrochloride is a potent, balanced, combined and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor with Kis of 34 and 37 nM, respectively. Synonyms: (E)-5-Fluoro-2-(3-((4-(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenoxy)methyl)styryl)benzo[d]thiazole hydrochloride; 1-[4-({3-[(E)-2-(5-Fluoro-1,3-benzothiazol-2-yl)vinyl]benzyl}oxy)phenyl]-2-methyl-1H-imidazo[4,5-c]pyridine hydrochloride (1:1); Benzothiazole, 5-fluoro-2-[(E)-2-[3-[[4-(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenoxy]methyl]phenyl]ethenyl]-, hydrochloride (1:1). Grade: ≥95%. CAS No. 167011-22-5. Molecular formula: C29H22ClFN4OS. Mole weight: 529.03. |  |
| CP 96345 | CP 96345 is an effective and selective non-peptide NK1 receptor antagonist and has been found to show activities in restraining neurogenic inflammation in vivo. Uses: Hypnotics and sedatives. Synonyms: CP-96345; CP 96345; CP96345; (2S,3S)-N-(2-Methoxyphenyl)methyl-2-diphenylmethyl-1-azabicyclo[2.2.2]octan-3-amine. Grade: ≥98% by HPLC. CAS No. 132746-60-2. Molecular formula: C28H32N2O. Mole weight: 412.57. | |
| CP-96,345 | CP-96,345 is a specific, highly potent, and orally active tachykinin and substance P receptor non-peptide inhibitor. CP-96,345 prevents the drop in blood pressure evoked by substance P and neurokinin A. CP-96,345 can be used for researching neurogenic inflammation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 132746-60-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108482. |  |
| CP-96486 | CP-96486 is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor, with Kis of 20 and 24 nM, respectively. Synonyms: Quinoline, 7-chloro-2-[(1E)-2-[3-[[4-(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenoxy]methyl]phenyl]ethenyl]-; (E)-7-Chloro-2-[2-[3-[[4-(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenoxy]methyl]phenyl]ethenyl]quinoline; 7-Chloro-2-[(1E)-2-[3-[[4-(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenoxy]methyl]phenyl]ethenyl]quinoline. Grade: ≥95%. CAS No. 139401-45-9. Molecular formula: C31H23ClN4O. Mole weight: 502.99. | |
| CP 99433 | CP 99433, a fluoroquinolone derivative, has been found to be a Type II DNA topoisomerase inhibitor that could be probably effective as an antibacterial agent. Synonyms: CP 99433; CP99433; CP-99433. 3-Azabicyclo[3.1.0]hexane, 1,8-naphthyridine-3-carboxylic acid deriv; 1,?8-Naphthyridine-3-carboxylic acid, 7-(6-amino-3-azabicyclo[3.1.0]?hex-3-yl)?-1-cyclopropyl-6-fluoro-1,?4-dihydro-4-oxo-, (1α,?5α,?6α)?-. Grade: 98%. CAS No. 147059-71-0. Molecular formula: C17H17FN4O3. Mole weight: 344.34. | |
| CP 99994 dihydrochloride | The hydrochloride salt form of CP 99994, which is a high affinity NK1 antagonist and could attenuate endothelium-dependent contraction induced by substance P. Synonyms: CP 99994 dihydrochloride; CP99994 dihydrochloride; CP-99994 dihydrochloride; (2S,3S)-N-[(2-Methoxyphenyl)methyl]-2-phenyl-3-piperidinamine dihydrochloride. Grade: ≥99% by HPLC. CAS No. 145148-39-6. Molecular formula: C19H24N2O.2HCl. Mole weight: 369.33. | |
| CPA inhibitor | CPA inhibitor is a potent inhibitor for carboxypeptidase A (CPA). Synonyms: carboxypeptidase inhibitor; Benzenepropanoic acid. alpha.-[[hydroxy(2-phenylacetyl)amino]methyl]-. Grade: >98%. CAS No. 223532-02-3. Molecular formula: C18H19NO4. Mole weight: 313.35. | |
| CPA inhibitor | CPA inhibitor (Compound 5) (Carboxypeptidase inhibitor) is an orally active competitive carboxypeptidase A (CPA) inhibitor with a Ki value of 0.32 μM. CPA inhibitor blocks the activity of carboxypeptidase A3 (CPA3). CPA activator activates the Wnt/Lrp6/β-catenin signaling pathway. CPA inhibitor reduces epithelial damage. CPA inhibitor is applicable to research related to inflammatory bowel disease, including ulcerative colitis and Crohn's disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Carboxypeptidase inhibitor. CAS No. 223532-02-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-70005. | |
| CPCCOEt | CPCCOEt has been found to be a mGluR-1 antagonist. Synonyms: 7-(Hydroxyimino)cyclopropa[b]chromen-1a-carboxylate ethyl ester. Grade: ≥99% by HPLC. CAS No. 179067-99-3. Molecular formula: C13H13NO4. Mole weight: 247.25. | |
| CP (Chlorinated Paraffin) | Chlorinated paraffin is a complex chemical compound that is used as a flame retardant, plasticizer, and lubricant in a variety of industrial and consumer products. It is a white or pale yellow, waxy solid that has a strong, chlorine-like odor. Uses: CP is typically used in the production of rubber, plastics, paints, and coatings. It is also used as a flame retardant in textiles, as a lubricant in metalworking fluids, and as a plasticizer in PVC and other polymers. Group: Synthetic. Alternative Names: Chlorinated alkanesChlorinated alkenesChlorinated paraffinsPolychlorinated n-alkanesPolychlorinated n-alkenes. Grades: Technical Grade. CAS No. 85535-85-9. |  |
| CpCpp | CpCpp is a compound used in studying a diverse array of malignant neoplasms, intricate neurological impairments and intractable autoimmune maladies. Synonyms: (CMPCPP); Cytidine-5'-[(α,β)-methyleno]triphosphate, Sodium salt. Grade: ≥ 95% by HPLC. CAS No. 101553-55-3. Molecular formula: C10H18N3O13P3 (free acid). Mole weight: 481.18 (free acid). | |
| CPCR4-2 | CPCR4-2 can be used to detect different tumor entities and other diseases. Synonyms: Pentixafor. CAS No. 1341207-62-2. Molecular formula: C60H80N14O14. Mole weight: 1221.36. | |
| CPD-10 | CPD-10 is a potent CCND1 and CDK4 PROTAC degrader. CPD-10 exhibits anti-proliferative effects on tumor cells and can also induce apoptosis. CPD-10 can be used for the study of breast cancer and lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3055471-57-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-168660. | |
| CPD-1224 | CPD-1224 is an orally effective ALK inhibitor, a derivative of an ALK inhibitor that connects to the cereblon ligand. CPD-1224 targets the EML4-ALK oncogenic fusion protein and degrades both ALK and the mutant forms L1196M/G1202R. CPD-1224 can slow down tumor growth[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2891620-68-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153386. | |
| CPD-39 | CPD-39 is a potent and orally active CCND1 and CDK4 heterobifunctional PROTAC degrader. CPD-39 shows anti-proliferation. (Pink: ligand for target protein (HY-50767); black: linker (HY-20240); Blue: E3 ligase ligand (HY-168667))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3055472-38-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-168664. | |
| CPDA | CPDA is a novel potent SH2 domain-containing inositol phosphatase 2 (SHIP2) inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 1415834-63-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18685. | |
| CPDA | CPDA, a 4-substituted 2-pyridin-2-ylamide, has potential to inhibit SHIP2 which was found to enhance insulin signaling through the Akt pathway in viro and greatly improved abnormal glucose metabolism in diabetic animals. Synonyms: N-[4-[(4-chlorophenyl)methoxy]pyridin-2-yl]-2-(2,6-difluorophenyl)acetamide CPDA CHEMBL2337808 SCHEMBL14156872 AKOS027447209 CS-4991 AK517293 HY-18685 N-[4-(4-Chlorobenzyloxy)-2-pyridyl]-2,6-difluorobenzeneacetamide N-(4-((4-Chlorobenzyl)oxy)pyridin-2-yl). CAS No. 1415834-63-7. Molecular formula: C20H15ClF2N2O2. Mole weight: 388.79. | |
| CpdD hydrochloride | CpdD hydrochloride is a selective ghrelin receptor (GhrR aka GHSR-1a) antagonist. Synonyms: N-[(1R)-1-[3-[(4-bromophenyl)methyl]-1,2,4-oxadiazol-5-yl]-3-phenylpropyl]-3-(diethylamino)propane-1-sulfonamide hydrochloride. Grade: 99%. Molecular formula: C25H33BrN4O3S.HCl. Mole weight: 585.98. | |
| CPE-135A | CPE-135A. |  |
| cPEPCK inhibitor | cPEPCK inhibitor is the first GTP-competitive inhibitor of human cytosolic phosphoenolpyruvate carboxykinase (PEPCK or cPEPCK). Synonyms: N-[4-[1-(2-Fluorobenzyl)-3-butyl-2,6-dixo-2,3,6,7-tetrahydro-1H-purin-8-ylmethyl]phenyl]acetamide. Grade: 98%. CAS No. 628279-07-2. Molecular formula: C25H26FN5O3. Mole weight: 463.5. | |
| C-Peptide 1 (rat) | C-Peptide 1 (rat) specifically binds to G-protein-coupled membrane receptors in the nanomolar concentration range, and subsequently activates Ca2+-dependent intracellular signaling pathways. This leads to a stimulation of the activity of both Na+-K+-ATPase, and endothelial nitric oxide synthase. Administration of C-peptide to streptozotocin induced diabetic rats elicited a substantial increase in whole-body glucose turnover. Synonyms: Insulin 1 Precursor (57-87) (rat); H-Glu-Val-Glu-Asp-Pro-Gln-Val-Pro-Gln-Leu-Glu-Leu-Gly-Gly-Gly-Pro-Glu-Ala-Gly-Asp-Leu-Gln-Thr-Leu-Ala-Leu-Glu-Val-Ala-Arg-Gln-OH; L-alpha-glutamyl-L-valyl-L-alpha-glutamyl-L-alpha-aspartyl-L-prolyl-L-glutaminyl-L-valyl-L-prolyl-L-glutaminyl-L-leucyl-L-alpha-glutamyl-L-leucyl-glycyl-glycyl-glycyl-L-prolyl-L-alpha-glutamyl-L-alanyl-glycyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-threonyl-L-leucyl-L-alanyl-L-leucyl-L-alpha-glutamyl-L-valyl-L-alanyl-L-arginyl-L-glutamine. Grade: ≥95%. CAS No. 41475-27-8. Molecular formula: C140H228N38O51. Mole weight: 3259.53. | |
| C-Peptide 2 (rat) | C-Peptide 2 (rat), a peptide composed of 31 amino acid residues, can effectively improve glucose utilization in streptozotocin induced diabetic rats. It is a component of proinsulin, and can inhibit glucose-induced insulin secretion. Synonyms: Preproinsulin 2 (57-87) (rat); H-Glu-Val-Glu-Asp-Pro-Gln-Val-Ala-Gln-Leu-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Asp-Leu-Gln-Thr-Leu-Ala-Leu-Glu-Val-Ala-Arg-Gln-OH; L-alpha-glutamyl-L-valyl-L-alpha-glutamyl-L-alpha-aspartyl-L-prolyl-L-glutaminyl-L-valyl-L-alanyl-L-glutaminyl-L-leucyl-L-alpha-glutamyl-L-leucyl-glycyl-glycyl-glycyl-L-prolyl-glycyl-L-alanyl-glycyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-threonyl-L-leucyl-L-alanyl-L-leucyl-L-alpha-glutamyl-L-valyl-L-alanyl-L-arginyl-L-glutamine; Insulin 2 Precursor (57-87) (rat); Proinsulin 2 (33-63) (rat). Grade: ≥95% by HPLC. CAS No. 41594-08-5. Molecular formula: C135H222N38O49. Mole weight: 3161.43. | |
| C-Peptide, dog | C-Peptide, dog is a component of proinsulin. C-peptide is a marker of insulin secretion in understanding the pathophysiology of type 1 and type 2 diabetes. Synonyms: C-Peptide (dog). Grade: >95% by HPLC. CAS No. 39016-05-2. Molecular formula: C137H225N37O49. Mole weight: 3174.47. | |
| CPF-AM1 | CPF-AM1 is a novel insulinotropic peptide from the skin secretion of the clawed frog, Xenopus amieti. Synonyms: caerulein-precursor fragment AM1. | |
| CPF-AM4 | The source of CPF-AM4 is the octoploid frog Xenopus amieti (Pipidae). CPF-AM4 has antibacterial activity against Escherichia coli and Staphylococcus aureus. Grade: >98% by HPLC. | |
| CPF-B1 | CPF-B1 is produced by Xenopus borealis. The peptide with the greatest potential for development into a therapeutically valuable anti-infective agent was CPF-B1 with MIC=5 microM against E. coli, MIC=5 microM against S. aureus, and MIC=25 microM against Candida albicans, and low hemolytic activity against human erythrocytes (LC(50)>200 microM). Synonyms: GLGSLLGKAFKIGLKTVGKMMGGAPREQ; CPF-B1. Molecular formula: C126H218N36O34S2. Mole weight: 2845.4. | |
| CPF-C1 | CPF-C1 is a typical cationic antimicrobial peptide that was originally isolated from the tetraploid frog Xenopus clivii. CPF-C1 has potent antimicrobial activity against both sensitive and multidrug-resistant bacteria. | |
| CPF-L1 | CPF-L1 was found in Xenopus lenduensis. It has antibacterial activity. | |
| CPF-L2 | CPF-L2 was found in Xenopus lenduensis. It has antibacterial activity. | |
| CPF-P2 | CPF-P2 has antibacterial activity against E. coli (MIC=25 uM) and S. aureus (MIC= 6 uM). The source of CPF-P2 is skin secretions, Xenopus petersii, Africa. Grade: >95% by HPLC. | |
| CPF-P3 | CPF-P3 has antibacterial activity against E. coli (MIC=12.5 uM) and S. aureus (MIC=6 uM). The source of CPF-P3 is skin secretions, Xenopus petersii, Africa. Grade: >98% by HPLC. | |
| CPF-P4 | CPF-P4 has antibacterial activity against E. coli (MIC=25 uM) and S. aureus (MIC=6 uM). The source of CPF-P4 is skin secretions, Xenopus petersii, Africa. Grade: >96% by HPLC. | |
| CPF-P5 | CPF-P5 was found in Xenopus petersii. It has antibacterial activity. | |
| CPF-PG1 | CPF-PG1 from X. pygmaeus combined high antimicrobial potency against Staphylococcus aureus (MIC=6 μM) with relatively low hemolytic activity (LC(50)=145 μM). | |
| CPF-SE1 | The source of CPF-SE1 is Cameroon Clawed Frog, the tetraploid frog Silurana epitropicalis SE1, Africa. It moderately active against E. coli (MIC=40 uM) and highly active against S. aureus MRSA (MIC=2.5 uM). | |
| CPF-SE2 | The source of CPF-SE2 is Cameroon Clawed Frog, the tetraploid frog Silurana epitropicalis SE1, and Silurana paratropicalis, Africa. It moderately active against E. coli and highly active against S. aureus and MRSA (MIC=2.5 uM). | |
| CPF-St4 | CPF-St4 was found in the African clawed frog Silurana tropicalis. It is active against E. coli (MIC 2-4 uM), P. aeruginosa (MIC 4-8 uM), S. aureus (MIC 1 uM), M. luteus (MIC 0.5 uM), and S. cerevisiae (MIC 16 uM). CPF-St4 is also toxic to erythrocytes (HC50 64 uM) and T-lymphocytes (IC50 2 uM). | |
| CPF-St5 | CPF-St5 was found in the African clawed frog Silurana tropicalis. It exerts antimicrobial effects against Gram-positive bacteria, Gram-negative bacteria, and fungi. | |
| CPF-St6 | CPF-St6 was found in the African clawed frog Silurana tropicalis. It exerts antimicrobial effects against Gram-positive bacteria, Gram-negative bacteria, and fungi. | |
| CPF-St7 | CPF-St7 was found in the African clawed frog Silurana tropicalis. It exerts antimicrobial effects against Gram-positive bacteria, Gram-negative bacteria, and fungi. | |
| CPFX2090 | CPFX2090 is a cephalosporin antibacterial compound. Synonyms: 5-chloro-1-ethyl-3-(hydroxymethyl)-6,7-bis((4-methoxybenzyl)oxy)quinolin-4(1H)-one. CAS No. 1429439-25-7. Molecular formula: C28H28ClNO6. Mole weight: 509.98. | |
| CPFX4158 | CPFX4158 is a mannose deriviative and an antibacterial agent. Synonyms: CPFX-4158. CAS No. 1804962-84-2. Molecular formula: C51H55NO19. Mole weight: 985.99. | |
| CPG52364 | CPG52364 a small molecule toll-like receptor(TLR) antagonist, which is a type I transmembrane receptors and the central components of the innate immune system. It has recently completed phase 1 clinical trial for SLE therapy. Uses: Cpg52364 is used for the sle therapy. Synonyms: CPG-52364; CPG 52364; CPG52364; 6,7-Dimethoxy-2-(4-(4-methylpiperazin-1-yl)phenyl)-N-(2-morpholinoethyl)quinazolin-4-amine. Grade: >98%. CAS No. 1093135-60-4. Molecular formula: C27H36N6O3. Mole weight: 492.62. | |
| CPG-52364 | CPG-52364 (compound 2) is a TLR9 antagonist. CPG-52364 inhibits the HEK293-hTLR9 cell with an IC50 value of 4.6 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1093135-60-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-120538. | |
| CPG52364 sulfate | CPG52364 sulfate is the sulfate form of CPG52364, which is a small molecule toll-like receptor(TLR) antagonist. It has recently completed phase 1 clinical trial for SLE therapy. Uses: Cpg52364 sulfate is used for the sle therapy. Synonyms: CPG-52364 sulfate; CPG 52364 sulfate; CPG52364 sulfate; 6,7-Dimethoxy-2-(4-(4-methylpiperazin-1-yl)phenyl)-N-(2-morpholinoethyl)quinazolin-4-amine sulfate. Grade: >98%. CAS No. 1093135-62-6. Molecular formula: C27H38N6O7S. Mole weight: 590.70. | |
| c-Phenanthren-9-yl-methylamine | c-Phenanthren-9-yl-methylamine. Alternative Names: RARECHEM AL BW 0139;C-PHENANTHREN-9-YL-METHYLAMINE. CAS No. 15398-91-1. Product ID: ACM15398911. Molecular formula: C15H13N. Mole weight: 207.27. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| c(phg-isoDGR-(NMe)k) | c(phg-isoDGR-(NMe)k) is a selective and potent α5β1-integrin ligand with IC50 of 2.9 nM. Grade: >98%. CAS No. 1844830-65-4. Molecular formula: C27H41N9O7. Mole weight: 603.67. | |
| C-Phycocyanin | C-phycocyanin (C-PC) is a protein pigment which is also widely used as an excellent nutrient supplement for human beings. Uses: Scientific research. Category: Signaling pathways. Alternative Names: C-PC. CAS No. 11016-15-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1025. | |
| C-phycocyanin α-cysteine-84 phycocyanobilin lyase | The enzyme, characterized from the cyanobacterium Synechococcus elongatus PCC 7942, catalyses the covalent attachment of the phycobilin chromophore phycocyanobilin to cysteine 84 of the α subunit of the phycobiliprotein C-phycocyanin. Group: Enzymes. Synonyms: cpcE (gene name); cpcF (gene name). Enzyme Commission Number: EC 4.4.1.32. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5335; C-phycocyanin α-cysteine-84 phycocyanobilin lyase; EC 4.4.1.32; cpcE (gene name); cpcF (gene name). Cat No: EXWM-5335. |  |
| CPI1 | CPI1 is a multidrug resistance protein 1 (MRP1) inhibitor with a Ki value of 100 nM. CPI1 binds to the same substrate-binding site as leukotriene C4, stabilizes MRP1 in an apo-like inward-facing conformation, blocks the conformational changes required for ATP hydrolysis and substrate transport, and inhibits the ATPase activity of human and bovine MRP1. CPI1 serves as a tool for investigating the substrate transport mechanism of MRP1. CPI1 is applicable to research related to cancer multidrug resistance[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3085809-95-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P10856. | |
| CPI-1189 | CPI-1189 is an inhibitor of TNF-α release with the potential use to treat sciatica and postherpetic neuralgia. Synonyms: 4-Acetamido-N-tert-butylbenzamide; CPI-1189; REN-1189; REN-1654; CPI1189; REN1189; REN1654; CPI 1189; REN 1189; REN 1654. CAS No. 183619-38-7. Molecular formula: C13H18N2O2. Mole weight: 234.299. | |
| CPI-1205 | A highly potent and selective EZH2 inhibitor (biochemical IC50=2 nM, cellular EC50=32 nM). Synonyms: CPI-1205; CPI 1205; CPI1205; N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-2-methyl-1-[(1R)-1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indole-3-carboxamide; (R)-N-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide; CPI-1205. CAS No. 1621862-70-1. Molecular formula: C27H33F3N4O3. Mole weight: 518.57. | |
| CPI-1328 | CPI-1328 is a highly potent second-generation EZH2 inhibitor with a Ki of 63 fM. Synonyms: 1,3-Dioxolo[4,5-g]isoquinolin-5(6H)-one, 9-chloro-6-[[1,2-dihydro-6-methyl-4-(methylthio)-2-oxo-3-pyridinyl]methyl]-2-[trans-4-(dimethylamino)cyclohexyl]-7,8-dihydro-2,4-dimethyl-, (2R)-; (R)-9-chloro-2-((1r,4R)-4-(dimethylamino)cyclohexyl)-2,4-dimethyl-6-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinolin-5(6H)-one; CPI1328; CPI 1328. CAS No. 2390367-27-6. Molecular formula: C28H36ClN3O4S. Mole weight: 546.12. | |
| CPI-1612 | CPI-1612 is a highly potent, orally active EP300/CBP histone acetyltransferase (HAT) inhibitor with an IC50 of 8.1 nM for EP300 HAT. CPI-1612 has an anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2374971-81-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136285. | |
| CPI-169 | CPI-169 is a novel and potent EZH2 inhibitor, it decreases cellular levels of H3K27me3 and triggers cell cycle arrest and apoptosis in a variety of cell lines. Synonyms: CPI-169; CPI 169; CPI169. Grade: >98%. CAS No. 1450655-76-1. Molecular formula: C27H36N4O5S. Mole weight: 528.66. | |
| CPI 203 | CPI 203. Group: Biochemicals. Grades: Purified. CAS No. 1446144-04-2. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| CPI-203 | CPI-203 is a novel potent, selective and cell permeable inhibitor of BET bromodomain, with an IC50 value of appr 37 nM (BRD4 α-screen assay). Uses: Scientific research. Category: Signaling pathways. CAS No. 1446144-04-2. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15846. | |
| CPI-203 | CPI-203 is a BET bromodomain inhibitor. It inhibits BRD4 in vitro and in cells, and causes G1 cell cycle arrest. It also arrests the growth of T cell acute lymphoblastic leukemia cells in vitro (EC50 = 91.2 nM). Synonyms: CPI203; CPI-203; CPI 203; TEN010; TEN 010; TEN010; JQ-2; JQ 2; JQ2; RG-6146; RG 6146; RG-6146; RO6870810; RO-6870810; RO 6870810. (6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide. Grade: >98%. CAS No. 1446144-04-2. Molecular formula: C19H18ClN5OS. Mole weight: 399.90. | |
| CPI-268456 | CPI-268456 is a ligand of bromodomain-containing protein 4 (BRD4). It binds to BRD4 and inhibits LPS-induced IL-6 secretion in THP-1 cells. Synonyms: 2-[(4S)-8-chloro-6-(4-chlorophenyl)-1-methyl-4H-[1,2]oxazolo[5,4-d][2]benzazepin-4-yl]acetamide. Grade: ≥98%. CAS No. 1380087-86-4. Molecular formula: C20H15Cl2N3O2. Mole weight: 400.3. | |
| CPI-360 | CPI-360 is a potent, selective,and SAM-competitive EZH1 inhibitor with IC50 of 102.3 nM, >100-fold selectivity over other methyltransferases. Synonyms: CPI360; CPI 360. Grade: 98%. CAS No. 1802175-06-9. Molecular formula: C25H31N3O4. Mole weight: 437.53. | |
| CPI 4203 | CPI 4203 is a selective inhibitor of KDM5 demethylases structurally related to CPI 455. Synonyms: CPI-4203; CPI 4203; CPI4203; 6-ethyl-7-oxo-5-(o-tolyl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile. Grade: 99%. CAS No. 1628214-07-2. Molecular formula: C16H14N4O. Mole weight: 278.31. | |
| CPI-444 | CPI-444 is a potent, orally available, selective antagonist of the adenosine A2A receptor that has been well tolerated in Ph 1/1b studies in non-oncology indications. Synonyms: (S)-7-(5-methylfuran-2-yl)-3-((6-(((tetrahydrofuran-3-yl)oxy)methyl)pyridin-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine; CPI-444; CPI 444; CPI444; V81444; V-81444; V 81444. CAS No. 1202402-40-1. Molecular formula: C20H21N7O3. Mole weight: 407.17. | |
| CPI 455 | CPI 455 is a selective inhibitor of KDM5 demethylases (IC50 value 10 nM for inhibition of full length KDM5A) that specifically alters H3K4 methylation (H3K4me3) in vitro and reduces survival of drug-tolerant cancer cells. Uses: Antitumor agent for drug-tolerant cancer. Synonyms: CPI-455; CPI-455; CPI-455; 6-Isopropyl-7-oxo-5-phenyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile. Grade: 99%. CAS No. 1628208-23-0. Molecular formula: C16H14N4O. Mole weight: 278.31. | |
| CPI-455 | CPI-455 is a specific, pan-KDM5 inhibitor with an IC50 of 10 nM for KDM5A. CPI-455 mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1628208-23-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100421. | |
| CPI-455 analogue | CPI-455 analogue is an analogue of CPI-455 which is a KDM5 inhibitor. Molecular formula: C16H14N4O. Mole weight: 278.31. | |
| CPI-455 hydrochloride | CPI-455 is a specific inhibitor of KDM5 with IC50 of 10 ± 1 nM for full-length KDM5A in enzymatic assays. Synonyms: 7-oxo-5-phenyl-6-propan-2-yl-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile hydrochloride. Grade: ≥99%. CAS No. 2095432-28-1. Molecular formula: C16H15ClN4O. Mole weight: 314.77. | |
| CPI-455 hydrochloride | CPI-455 hydrochloride is a specific, pan-KDM5 inhibitor with an IC50 of 10 nM for KDM5A. CPI-455 hydrochloride mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2095432-28-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-100421A. | |
| CPI-613 | CPI-613 is a racemic mixture of the enantiomers of a synthetic alpha-lipoic lipoic acid analogue with potential chemopreventive and antineoplastic activities. Although the exact mechanism of action is unknown, alpha-lipoic acid analogue CPI-613 has been shown to inhibit metabolic and regulatory processes required for cell growth in solid tumors. Both enantiomers in the racemic mixture exhibit antineoplastic activity. The mechanism-of-action of CPI-613 appears distinct from the current classes of anti-cancer agents used in the clinic. CPI-613 demonstrates both in vitro and in vivo anti-tumor activity. CPI-613 was known to strongly disrupt tumor mitochondrial metabolism. CPI-613 disruption of tumor mitochondrial metabolism is followed by efficient commitment to cell death by multiple, apparently redundant pathways, including apoptosis, in all tested cancer cell lines. Further, CPI-613 shows strong antitumor activity in vivo against human non-small cell lung and pancreatic cancers in xenograft models with low side-effect toxicity. Synonyms: CPI613; CPI 613; Devimistat; 6,8-bis(benzylthio)octanoic acid. Grade: 98%. CAS No. 95809-78-2. Molecular formula: C22H28O2S2. Mole weight: 388.59. | |
| CPI-613 (Devimistat) | Devimistat (CPI-613), a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase in NCI-H460 cell line, disrupts tumor cell mitochondrial metabolism. CPI-613 induces apoptosis in pancreatic cancer cells. Phase 2. Group: Inhibitors. CAS No. 95809-78-2. Pack Sizes: 5mg. Product ID: S2776. Formula: C22H28O2S2. Smiles: C1=CC=C(C=C1)CSCCC(CCCCC(=O)O)SCC2=CC=CC=C2. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| CPI-637 | CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor with IC50 of 0.03±0.01μM and 11.0±0.6 μM for CBP/EP300 and BRD4, respectively. CPI-637 displayed a >700-fold selectivity over the BET family of bromodomains (BRD4 IC50=11.0 ± 0.6 μM). Synonyms: CPI-637; CPI 637; CPI637. (4R)-4-methyl-6-[1-methyl-3-(1-methylpyrazol-4-yl)indazol-5-yl]-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one; CPI-637; SCHEMBL17673230. Grade: >98%. CAS No. 1884712-47-3. Molecular formula: C22H22N6O. Mole weight: 386.459. | |
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