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| Product | Description | |
|---|---|---|
| CWHM-12 | CWHM-12 is a potent inhibitor of ?V integrins with IC50s of 0.2, 0.8, 1.5, and 1.8 nM for ?v?8, ?v?3, ?v?6, and ?v?1. Uses: Scientific research. Group: Signaling pathways. CAS No. 1564286-55-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18644. |  |
| CWHM-12 | CWHM-12 Inhibitor. Uses: Scientific use. Product Category: TQ0250. CAS No. 1564286-55-0. |  |
| CWHM-12 | CWHM 12 demonstrated high potency against all of the five possible β subunit binding partners (αvβ1, αvβ3, αvβ5, αvβ6 and αvβ8) in in vitro ligand-binding assays, with somewhat less potency against αvβ5 than against the other αv integrins. Treated mice with CCl4 for 3 weeks to establish fibrotic disease and then treated with CWHM 12 or vehicle for the final 3 weeks of CCl4. CWHM12 significantly reduced liver fibrosis even after fibrotic disease had been established. Similar to our findings in the liver, administration of CWHM 12 significantly inhibited progression of pulmonary fibrosis. Synonyms: CWHM12; CWHM 12; CWHM-12. Grade: >98%. CAS No. 1564286-55-0. Molecular formula: C26H32BrN5O6. Mole weight: 590.47. |  |
| CWI1-2 | CWI1-2 is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and shows promising anti-leukemic effects[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2408590-36-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153274. | |
| CX08005 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| CX08005 | CX08005 is a competitive inhibitor of PTP1B (IC50 = 0.781 μM). CX08005 binds catalytic P-loop of enzyme. It exhibits some selectivity for PTP1B over other protein tyrosine phosphatases, except TCPTP. Synonyms: 2-[[[2-(Tetradecyl)phenyl]amino]carbonyl]benzoic acid. Grade: ≥98% by HPLC. CAS No. 1256341-22-6. Molecular formula: C28H39N04. Mole weight: 453.61. | |
| CX-157 | CX-157 is a monoamine oxidase (MAO)-A inhibitor potentially for the treatment of depression and anxiety. Synonyms: CX157; CX 157; Phenoxathiin, 3-fluoro-7-(2,2,2-trifluoroethoxy)-, 10,10-dioxide; TriRima; Tyrima. CAS No. 205187-53-7. Molecular formula: C14H8F4O4S. Mole weight: 348.27. | |
| CX4338 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CX 4945 hydrochloride | CX 4945 hydrochloride is an orally bioactive and ATP-competitive casein kinase 2 (CK2) inhibitor. CX 4945 inhibits proliferation and migration in a panel of cancer cell lines which overexpresses CK2. Uses: Antitumor agent. Synonyms: CX 4945 hydrochloride; CX-4945 hydrochloride; CX4945 hydrochloride; Silmitasertib HCl; Silmitasertib hydrochloride. Grade: 98%. CAS No. 2108312-01-0. Molecular formula: C19H12ClN3O2.HCl. Mole weight: 386.23. | |
| CX-4945 sodium salt | CX-4945 (Silmitasertib) sodium salt is a potent and selective ATP-competitive small molecule protein kinase CK2 inhibitor with a Ki and an IC50 of 0.38 and 1 nM for recombinant human CK2α, respectively. Synonyms: Silmitasertib sodium salt; CX-4945 sodium salt; CX 4945 sodium salt; CX4945 sodium salt. Grade: >98%. CAS No. 1309357-15-0. Molecular formula: C19H11ClN3NaO2. Mole weight: 371.75. | |
| CX-5011 | CX-5011 is a very potent and selective CK2 inhibitor, which induces cell death in tumor cells. Synonyms: CX5011; CX 5011; Pyrimido[4,5-c]quinoline-8-carboxylic acid, 5-[(3-ethynylphenyl)amino]-. Grade: 98%. CAS No. 1009821-06-0. Molecular formula: C20H12N4O2. Mole weight: 340.34. | |
| CX516 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| CX516 | CX516 (BDP 12) is an ampakine and acts as an AMPA receptor positive allosteric modulator for the research of Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI) [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BDP 12. CAS No. 154235-83-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10933. | |
| CX546 | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| CX546 | It is one of a series of AMPA modulators for the potential treatment of Alzheimer's disease, schizophrenia, and mild cognitive impairment (MCI). An ampakine drug that facilitates activation of glutamatergic AMPA receptors. Synonyms: (2,3-Dihydro-1,4-benzodioxin-6-yl)-1-piperidinylmethanone; 1-[(2,3-Dihydro-1,4-benzodioxin-6-yl)carbonyl]piperidine; CX546; CX 546; CX-546; UNII-PV6YEC8983; GR 87; GR-87; BDP 17; GR87; BDP17; BDP-17. Grade: >98%. CAS No. 215923-54-9. Molecular formula: C14H17NO3. Mole weight: 247.29. | |
| CX546 | CX546 is a first-generation and selective benzamide-type positive AMPAR modulator. CX546 is a prototypical ampakine agent and has antipsychotic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 215923-54-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12505. | |
| CX 546 | AMPA potentiator. Group: Biochemicals. Alternative Names: (2,3-Dihydro-1,4-benzodioxin-6-yl)-1-piperidinylmethanone. Grades: Highly Purified. CAS No. 215923-54-9. Pack Sizes: 10mg, 50mg. Molecular Formula: C14H17NO3. US Biological Life Sciences. |  Worldwide |
| CX-5461 | CX-5461 is a potent and oral rRNA synthesis inhibitor. It inhibits RNA polymerase I-driven transcription of rRNA with IC50s of 142, 113, and 54 nM in HCT-116, A375, and MIA PaCa-2 cells, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1138549-36-6. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13323. | |
| CX-5461 | CX-5461 is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcription of rRNA with IC50 of 142 nM, has no effect on Pol II, and possesses 250- to 300-fold selectivity for inhibition of rRNA transcription versus DNA replication and protein translation. Synonyms: CX-5461; CX 5461; CX5461. CAS No. 1138549-36-6. Molecular formula: C27H27N7O2S. Mole weight: 513.62. | |
| CX-5461 dihydrochloride | CX-5461 dihydrochloride is a potent and orally bioavailable Pol I-mediated rRNA synthesis inhibitor, with IC50s of 142, 113 and 54 nM in HCT-116, A375 and MIA PaCa-2 cells, respectively. It shows little or no effect on Pol II (IC50 ≥25 μM). Synonyms: 5H-Benzothiazolo[3,2-a][1,8]naphthyridine-6-carboxamide, 2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-N-[(5-methyl-2-pyrazinyl)methyl]-5-oxo-, hydrochloride (1:2). Grade: ≥98%. Molecular formula: C27H29Cl2N7O2S. Mole weight: 586.54. | |
| CX-5461 dihydrochloride | CX-5461 dihydrochloride is a potent and orally bioavailable inhibitor of Pol I-mediated rRNA synthesis, with IC50s of 142 nM in HCT-116, 113 nM in A375, and 54 nM in MIA PaCa-2 cells, and shows little or no effect on Pol II (IC50 ?25 ?M). Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13323A. | |
| CX546 (AMPA Positive Allosteric Modulator, CX546, CX-546, CX 546) | A positive allosteric modulator selective for the AMPA receptors. Used in studies related to Schizophrenia, neuroplasticity, Autism and neuronal differentiation. Group: Biochemicals. Grades: Highly Purified. CAS No. 215923-54-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CX 614 | Positive allosteric modulator of AMPA receptors. Group: Biochemicals. Alternative Names: 2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one. Grades: Highly Purified. CAS No. 191744-13-5. Pack Sizes: 10mg, 50mg. Molecular Formula: C13H13NO4. US Biological Life Sciences. | Worldwide |
| CX 614 | CX 614 has been found to be an AMPA modulator and has also been found to be an ampakine drug facilitating activation of glutamatergic AMPA receptors. Synonyms: CX614; CX 614; CX-614. 2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one. Grade: ≥99% by HPLC. CAS No. 191744-13-5. Molecular formula: C13H13NO4. Mole weight: 247.25. | |
| CX-6258 | CX-6258 is a potent, orally efficacious Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor with excellent biochemical potency and kinase selectivity. Synonyms: (E)-5-chloro-3-((5-(3-(4-methyl-1,4-diazepane-1-carbonyl)phenyl)furan-2-yl)methylene)indolin-2-one; CX6258; CX-6258; CX 6258. CAS No. 1202916-90-2. Molecular formula: C26H24ClN3O3. Mole weight: 461.946. | |
| CX-6258 | CX-6258 is a potent and kinase selective pan-Pim kinases inhibitor, with IC50s of 5 nM, 25 nM and 16 nM for Pim-1, Pim-2 and Pim-3, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1202916-90-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18095. | |
| CX-6258 Hydrochloride | CX-6258 shows antiproliferative activity against a panel of human cancer cell lines with IC50 of 0.02-3.7 μM, mostly sensitive to acute leukemia cell lines. Synonyms: CX-6258 HCl; CX 6258 hydrochloride; CX 6258 HCl; CX6258 HCl. Grade: >98%. CAS No. 1353859-00-3. Molecular formula: C26H25Cl2N3O3. Mole weight: 498.40. | |
| CX-6258 hydrochloride hydrate | The hydrochloride hydrate salt form of CX-6258, a pan-Pim kinases inhibitor, has been found to have strong antiproliferative potencies against human solid tumors and hematological malignancies. It has already been discontinued for Solid tumours. IC50: 5 n. Uses: The hydrochloride hydrate salt form of cx-6258 is a pan-pim kinases inhibitor that has been found to have strong antiproliferative potencies against human solid tumors and hematological malignancies. it has already been discontinued for solid tumours. ic5. Synonyms: CX-6258 hydrochloride hydrate; CX 6258 hydrochloride hydrate; CX6258 hydrochloride hydrate; C26H24ClN3O3.ClH.H2O; 2121AH; HY-18095A; CS-1530; W-6143; CS 1530; W 6143; CS1530; W6143. Grade: 98%. CAS No. 1353858-99-7. Molecular formula: C26H27Cl2N3O4. Mole weight: 516.42. | |
| CX-6258 hydrochloride hydrate | CX-6258 hydrochloride hydrate is a potent and kinase selective pan-Pim kinases inhibitor, with IC 50 s of 5 nM, 25 nM and 16 nM for Pim-1, Pim-2 and Pim-3, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1353858-99-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18095A. | |
| CX 717 | CX 717 is a positive allosteric modulator of AMPA receptor. Antidepressant-like effect. CX 717 can be used for the research of adult attention deficit hyperactivity disorder (ADHD) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 867276-98-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139897. | |
| CXCL16 from mouse | recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| CXCL16 human | recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| CXCR2 antagonist 2 | CXCR2 antagonist 2, a potent CXCR2 antagonist (IC50 = 95 nM), is used in cancer immunotherapy. Synonyms: 1-(3-fluoro-2-methylphenyl)-3-(8-hydroxy-1,1-dioxo-3,4-dihydro-2H-thiochromen-7-yl)urea. CAS No. 2647464-91-1. Molecular formula: C17H17FN2O4S. Mole weight: 364.39. | |
| CXCR2 antagonist 2 | CXCR2 antagonist 2 is a potent CXCR2 antagonist for cancer immunoresearch with an IC 50 value of 95 nM. Uses: Scientific research. Group: Signaling pathways. CAS No. 2647464-91-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139873. | |
| CXCR2 antagonist 3 | CXCR2 antagonist 3, a potent CXCR2 antagonist, has double-digit nanomolar potencies against CXCR2 and significantly inhibits neutrophil infiltration into air pouch. It reduces the infiltration of neutrophils and MDSCs, and enhances the infiltration of CD3+ T lymphocytes into Pan02 tumor tissues. Synonyms: Urea, N-(3-fluoro-2-methylphenyl)-N'-(8-hydroxy-1,1-dioxido-2H-1-benzothiopyran-7-yl)-. CAS No. 2647464-92-2. Molecular formula: C17H15FN2O4S. Mole weight: 362.38. | |
| CXCR2 antagonist, Cpd 19 - CAS 473728-67-5 | The CXCR2 antagonist, Cpd 19, also referenced under CAS 473728-67-5, controls the biological activity of CXCR2. Group: Fluorescence/luminescence spectroscopy. | |
| CXCR2 Antagonist, Cpd 19 (CXCR2 Inhibitor, 3-(2-(cyclopentylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide) | A cell-permeable, cyclobutenedione derivative that acts as a potent antagonist of chemokine receptor CXCR2 (IL8RB) (IC50 = 8nM). Reported to inhibit CXCR2-mediated chemotaxis in a CXCR2 expressing cell line (IC50 = 145nM). Exhibits good stability in human and rat liver microsomal preparations (>50% remaining after 30 min at 37°C). Group: Biochemicals. Grades: Highly Purified. CAS No. 473728-67-5. Pack Sizes: 2mg. US Biological Life Sciences. | Worldwide |
| CXCR2-IN-1 | CXCR2-IN-1 is a CXCR2 antagonist (pIC50 = 9.3) with favorable central nervous system penetration property (Br/Bl>0.45). Synonyms: 1-(2-chloro-3-fluorophenyl)-3-[4-chloro-2-hydroxy-3-(1-methylpiperidin-4-yl)sulfonylphenyl]urea. CAS No. 1873376-49-8. Molecular formula: C19H20Cl2FN3O4S. Mole weight: 476.35. | |
| CXCR2-IN-2 | CXCR2-IN-2 is a selective, brain penetrant and orally bioavailable CXCR2 antagonist with IC50s of 5.2 and 1 nM in β-arrestin assay and CXCR2 Tango assay, respectively. It inhibits human whole blood Gro-α induced CD11b expression (IC50 = 0.04 μM). It shows ~730-fold selectivity over CXCR1 and >1900-fold selectivity over all other chemokine receptors. Synonyms: 1-(4-Chloro-2-hydroxy-3-(((S)-3-methyltetrahydrofuran-3-yl)sulfonyl)phenyl)-3-((R)-2-methylcyclopent-2-en-1-yl)urea; 1-(4-Chloro-2-hydroxy-3-{[(3S)-3-methyltetrahydro-3-furanyl]sulfonyl}phenyl)-3-[(1R)-2-methyl-2-cyclopenten-1-yl]urea. Grade: ≥95%. CAS No. 1838123-21-9. Molecular formula: C18H23ClN2O5S. Mole weight: 414.90. | |
| CXCR301 | CXCR301. Molecular formula: C36H47N9O6. Mole weight: 701.80. | |
| CXCR3 Agonist, PS372424 | The CXCR3 Agonist, PS372424 controls the biological activity of CXCR3. This small molecule/inhibitor is primarily used for Cell Signaling applications. Group: Fluorescence/luminescence spectroscopy. | |
| CXCR3 Antagonist 6c | CXCR3 Antagonist 6c is a potent and selective chemokine CXCR3 antagonist (IC50 value of 60 nM in a calcium mobilization functional assay). It inhibits CXCR3 functional response to CXCL11 as measured by T-cell chemotaxis. Synonyms: 4-[2-[(3-chlorobenzoyl)amino]-4-[2-(2,4-dichlorophenyl)ethylcarbamoyl]phenyl]-N-ethyl-1,4-diazepane-1-carboxamide. Grade: 99%. CAS No. 870998-13-3. Molecular formula: C30H32Cl3N5O3. Mole weight: 616.97. | |
| CXCR3 Antagonist (GPR9 Antagonist, 4-cyano-N- (3-fluoro-4- (1H-tetrazol-5-yl) benzyl) -N- (2-fluorobenzyl) benzenesulfonamide, AS612568, CD183 Antagonist) | An arylsulfonamide derivative that acts as a CXCR3 antagonist (IC50 = 192nM against CXCL10-induced chemotaxis of hCXCR3-overexpressing L1.2 cells) with good aqueous solubility (>100uM at pH 7.4). Shown to be orally available in mice (83% bioavailability; t1/2 = 1h; 10mg/kg p.o.) in vivo and display a medium intrinsic clearance (CIint = 17uL/min/mg) in in vitro mouse liver microsome stability test. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C??H??F?N6O?S. US Biological Life Sciences. | Worldwide |
| CXCR4 antagonist 1 | CXCR4 antagonist 1 is a potent CXCR4 antagonist with anti-HIV activity. Synonyms: 1,4-Butanediamine, N4-[[4-[[(1H-imidazol-2-ylmethyl)[(1-methyl-1H-imidazol-2-yl)methyl]amino]methyl]phenyl]methyl]-N1,N1-dipropyl-; N-(4-{[(1H-imidazol-2-ylmethyl)-(1-methyl-1H-imidazol-2-ylmethyl)-amino]-methyl}-benzyl)-N',N'-dipropyl-butane-1,4-diamine. Grade: ≥98% (HPLC). CAS No. 675135-69-0. Molecular formula: C27H43N7. Mole weight: 465.68. | |
| CXCR4 antagonist 2 | CXCR4 antagonist 2 is an antagonist of CXCR4 with an IC50 of 47 nM. Synonyms: (S)-N-methyl-N-(((R)-5-((4-methylpiperazin-1-yl)amino)-1,2,3,4-tetrahydroisoquinolin-3-yl)methyl)-5,6,7,8-tetrahydroquinolin-8-amine. CAS No. 2243636-57-7. Molecular formula: C25H36N6. Mole weight: 420.59. | |
| CXCR4 Antagonist I, AMD3100 - CAS 155148-31-5 | The CXCR4 Antagonist I, AMD3100, also referenced under CAS 155148-31-5, controls the biological activity of CXCR4. This small molecule/inhibitor is primarily used for Cell Signaling applications. Group: Fluorescence/luminescence spectroscopy. | |
| CXCR4 Antagonist II - CAS 1258011-83-4 | The CXCR4 Antagonist II, also referenced under CAS 1258011-83-4, controls the biological activity of CXCR4. This small molecule/inhibitor is primarily used for Cell Signaling applications. Group: Fluorescence/luminescence spectroscopy. | |
| CXCR4 Antagonist III | The CXCR4 Antagonist III controls the biological activity of CXCR4. This small molecule/inhibitor is primarily used for Biochemicals applications. Group: Fluorescence/luminescence spectroscopy. | |
| CXCR4 Antagonist III (Fusin Antagonist III, N2- (4- ( (3- (Cyclohexylamino) propylamino) methyl) benzyl) -N4- (piperidin-4-yl) quinazoline-2,4-diamine, 2HCl) | A cell-permeable quinazoline compound that acts as a potent and reversible CXCR4 antagonist (IC50=36.2nM for SDF-1/CXCL12 binding to hCXCR4-transfected HEK293 membrane) with selectivity over closely related human chemokine receptors CXCR2, CCR2, CCR4 and CCR5 (IC50 >10uM). Shown to inhibit CXCL12-induced Ca2+-mobilization and cell migration in hCXCR4-HEK293 cells (IC50=100.1 and 41nM, respectively), and rapidly mobilize CXCR4+, CD34+ and CD133+ stem cells from bone marrow in C57BL/6 male mice (6mg/kg, s.c). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| CXCR4 Antagonist IV, TF14016 (Fusin Antagonist IV) | A 14-aa internally disulfide-bonded peptide that potently competes against SDF-1alpha/CXCL12 for CXCR4 binding (IC50 = 0.91nM; [SDF-1] = 100nM) and protects MT-4 cells against X4-HIV strain HIV-1IIIB infection (EC50 = 4nM in 5 d; MOI = 0.01) with no significant cytotoxicity (CC50 = 56uM; 5 d). Inhibits SDF-1-induced Ca2+ mobilization (IC50 = 4.5nM; [SDF-1] = 30nM; CXCR4-expressing CHO cells) in vitro and effectively prevents CXCR4-dependent 5BC-5 metastasis in NK-depleted SCID mice in vivo (10mg/kg i.p.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg. Molecular Formula: C???H???FN??O??S?. xH?O, Sequence: N alpha-4-fluorobenzoyl-Arg-Arg-Nal-Cys4-Tyr-Cit-Lys-D-Lys-Pro-Tyr-Arg-Cit-Cys¹3-Arg-NH2 (Disulfide bond: 4 ? 13; Nal = L-3-(2-naphthyl)alanine; Cit = L-citrulline). US Biological Life Sciences. | Worldwide |
| CXCR7 Agonist, VUF11207 | The CXCR7 Agonist, VUF11207 controls the biological activity of CXCR7. This small molecule/inhibitor is primarily used for Biochemicals applications. Group: Fluorescence/luminescence spectroscopy. | |
| CXCR7 antagonist-1 | CXCR7 antagonist-1 is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. CXCR7 antagonist-1 is useful in preventing tumor cell proliferation, tumor formation, inflammatory diseases, and many other diseases[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1613021-99-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139643. | |
| CXCR7 modulator 1 | CXCR7 modulator 1 is a potent and orally bioavailable peptoid hybrid CXCR7 modulator, with a Ki of 9 nM. Synonyms: cyclo[Ala(tBu)-Tza-D-Pro-N(Unk)Gly-Ser(Bn)-D-Phe]; Cyclo{3-(1,3-thiazol-4-yl)-L-alanyl-D-prolyl-N-[3-(2,4-difluorophenyl)propyl]glycyl-O-benzyl-L-seryl-D-phenylalanyl-4-methyl-L-leucyl}. Grade: ≥95%. CAS No. 2231812-31-8. Molecular formula: C48H57F2N7O7S. Mole weight: 914.07. | |
| CXCR7 modulator 2 | CXCR7 modulator 2 is a CXC Chemokine Receptor Type 7 (CXCR7) modulator, with a Ki of 13 nM. Synonyms: 1H-1,4-Diazepine-1-propanamide, 4-(7-ethylimidazo[1,2-a]pyridin-8-yl)hexahydro-β-[1-[(1R,2S,4S)-7-oxabicyclo[2.2.1]hept-2-ylcarbonyl]-4-piperidinyl]-, (βS)-; (3S)-3-[4-(7-Ethylimidazo[1,2-a]pyridin-8-yl)-1,4-diazepan-1-yl]-3-{1-[(1R,2S,4S)-7-oxabicyclo[2.2.1]hept-2-ylcarbonyl]-4-piperidinyl}propanamide. Grade: ≥98%. CAS No. 2227426-37-9. Molecular formula: C29H42N6O3. Mole weight: 522.68. | |
| CXD101 | CXD101 is a selective histone deacetylase (HDAC) inhibitor with IC50 of 63 nM, 570 nM and 550 nM for HDAC1, HDAC2 and HDAC3, respectively. It exhibits antineoplastic activity. Synonyms: HDAC-IN-4; CXD-101; CXD 101; N-(2-Aminophenyl)-4-(1-((1,3-dimethyl-1H-pyrazol-4-yl)methyl)piperidin-4-yl)benzamide. Grade: 99%. CAS No. 934828-12-3. Molecular formula: C24H29N5O. Mole weight: 403.52. | |
| CXL146 | CXL146 is a 4H-Chromene derivative that eliminates cancer cells with GRP78 overexpression via activating unfolded protein response-mediated apoptosis. Synonyms: Prop-2-ynyl 2-amino-6-(2-methylpyridin-4-yl)-4-(2-oxo-2-(prop-2-ynyloxy)ethyl)-4H-chromene-3-carboxylate. Grade: 99%. CAS No. 2244586-41-0. Molecular formula: C24H20N2O5. Mole weight: 416.43. | |
| cXMP | cXMP, a highly potent biomolecular tool, serves as a remarkable resource in the field of biomedicine due to its diverse applications. Its immense value lies in its prowess as a cyclic nucleotide analog, granting researchers the ability to delve deep into the intricate web of signaling pathways associated with cellular responses, encompassing the realm of drugs and diseases. Pertaining to research and drug discovery, cXMP assumes a pivotal role in unraveling the intricacies of cyclic nucleotide involvement in the regulation of various biochemical processes. Synonyms: Xanthosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. CAS No. 31319-70-7. Molecular formula: C10H10N4O8P · Na. Mole weight: 368.2. | |
| CY-09 | CY-09 is a selective and direct NLRP3 inhibitor. CY-09 directly binds to the ATP-binding motif of NLRP3 NACHT domain and inhibits NLRP3 ATPase activity, resulting in the suppression of NLRP3 inflammasome assembly and activation[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1073612-91-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103666. | |
| CY 208-243 | CY 208-243 is a D1DR receptor agonist and has been found to show antiparkinsonian activity in animal models. Synonyms: CY 208-243; CY-208-243; CY208243; (-)-(6aR,12bR)-4,6,6a,7,8,12b-Hexahydro-7-methylindolo[4,3-a]phenanthridin. Grade: ≥95% by HPLC. CAS No. 100999-26-6. Molecular formula: C19H18N2. Mole weight: 274.36. | |
| Cy2 Carboxylic acids | Cy2 Carboxylic acids. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 6-[2-[(E,3E)-3-(3-ethyl-1,3-benzoxazol-2-ylidene)prop-1-enyl]-1,3-benzoxazol-3-ium-3-yl]hexanoate. Product Category: Cyanine Fluorophores. Appearance: Solid powder. CAS No. 260430-02-2. Molecular formula: C25H27IN2O4. Mole weight: 546.41. Purity: 95%+. IUPACName: 6-[2-[(E,3Z)-3-(3-ethyl-1,3-benzoxazol-2-ylidene)prop-1-enyl]-1,3-benzoxazol-3-ium-3-yl]hexanoate. Canonical SMILES: CCN\1C2=CC=CC=C2O/C1=C\C=C\C3=[N+](C4=CC=CC=C4O3)CCCCCC(=O)[O-]. Product ID: ACM260430022-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Cy2-SE (iodine) | Cy2-SE iodine is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis[1]. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance[2]. Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Cyanine2 Succinimidyl Ester (iodine). CAS No. 186205-33-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-D0826. | |
| CY3 | Cy3 (Sulfo-Cyanine3) is an orange-fluorescent label for protein and nucleic acid (?ex=554, ?em=568). Uses: Scientific research. Group: Fluorescent dye. Alternative Names: Sulfo-Cyanine3. CAS No. 146368-13-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0822. | |
| Cy3-11-dCTP | Cy3-11-dCTP is a highly acclaimed fluorescent nucleotide derivative extensively utilized in the thriving biomedical industry, emerging as an indispensable instrument for the purpose of effectively and precisely marking DNA or RNA molecules in diverse scientific investigations. Notably, this remarkable compound seamlessly facilitates fluorescent in situ hybridization (FISH) endeavors and empowers meticulous microarray analysis. Grade: ≥ 95%. Mole weight: 1635. | |
| Cy3-11-dUTP | Cy3-11-dUTP is a fluorescent nucleotide used in various molecular biology applications including PCR and in situ hybridization. It is incorporated into DNA during synthesis and enables visualization of the amplified or hybridized product. This reagent is especially useful for identifying structural and functional changes in the genome associated with diseases. Grade: ≥ 95%. Mole weight: 1636. | |
| Cy3-11-UTP | Cy3-11-UTP, an indispensable fluorescent nucleotide analog in the biomedical industry, facilitates research in numerous avenues such as gene expression, protein interactions, and cell signaling pathways through RNA and DNA labeling. Its utility is undeniable in studies linking viral replication and cancer research. Grade: ≥ 95%. Mole weight: 1652.89. | |
| Cy3.5 carboxylic acid | Cy3.5 carboxylic acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Cy3.5-carboxylicacidchloride. Product Category: Cyanine Fluorophores. CAS No. 1144107-79-8. Molecular formula: C38H41ClN2O2. Mole weight: 593.2. Purity: 0.95. IUPACName: 6-[(2Z)-1,1-dimethyl-2-[(E)-3-(1,1,3-trimethylbenzo[e]indol-3-ium-2-yl)prop-2-enylidene]benzo[e]indol-3-yl]hexanoicacid;chloride. Canonical SMILES: CC1(C(=[N+](C2=C1C3=CC=CC=C3C=C2)C)C=CC=C4C(C5=C(N4CCCCCC(=O)O)C=CC6=CC=CC=C65)(C)C)C.[Cl-]. Product ID: ACM1144107798-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Cy3.5 Carboxylic acids | Cy3.5 Carboxylic acids. Uses: Designed for use in research and industrial production. Product Category: Cyanine Fluorophores. Appearance: Purple powder. CAS No. 1802928-88-6. Molecular formula: C38H41ClN2O2. Mole weight: 593.21. Purity: >97%. Product ID: ACM1802928886. Alfa Chemistry ISO 9001:2015 Certified. Categories: Cy3.5-cooh. | |
| Cy3B NHS ester | Cy3B NHS ester is a fluorescent dye compound that is commonly used in biomarking and fluorescent labeling experiments, especially for labeling biomolecules containing amino functional groups (amine groups), such as proteins, antibodies or peptides. Uses: Scientific research. Group: Fluorescent dye. CAS No. 228272-52-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1849. | |
| Cy3 Carboxylic acids | Cy3 Carboxylic acids. Uses: Designed for use in research and industrial production. Product Category: Cyanine Fluorophores. Appearance: Red powder. CAS No. 1251915-29-3. Molecular formula: C30H37ClN2O2. Mole weight: 493.09. Purity: >97%. Product ID: ACM1251915293. Alfa Chemistry ISO 9001:2015 Certified. | |
| CY3-HOF | CY3-HOF. Uses: Designed for use in research and industrial production. Purity: 0.98. Product ID: ACMA00064404. Alfa Chemistry ISO 9001:2015 Certified. | |
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