A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
CPF-P3 has antibacterial activity against E. coli (MIC=12.5 uM) and S. aureus (MIC=6 uM). The source of CPF-P3 is skin secretions, Xenopus petersii, Africa. Grade: >98% by HPLC.
CPF-P4
CPF-P4 has antibacterial activity against E. coli (MIC=25 uM) and S. aureus (MIC=6 uM). The source of CPF-P4 is skin secretions, Xenopus petersii, Africa. Grade: >96% by HPLC.
CPF-P5
CPF-P5 was found in Xenopus petersii. It has antibacterial activity.
CPF-PG1
CPF-PG1 from X. pygmaeus combined high antimicrobial potency against Staphylococcus aureus (MIC=6 μM) with relatively low hemolytic activity (LC(50)=145 μM).
CPF-SE1
The source of CPF-SE1 is Cameroon Clawed Frog, the tetraploid frog Silurana epitropicalis SE1, Africa. It moderately active against E. coli (MIC=40 uM) and highly active against S. aureus MRSA (MIC=2.5 uM).
CPF-SE2
The source of CPF-SE2 is Cameroon Clawed Frog, the tetraploid frog Silurana epitropicalis SE1, and Silurana paratropicalis, Africa. It moderately active against E. coli and highly active against S. aureus and MRSA (MIC=2.5 uM).
CPF-St4
CPF-St4 was found in the African clawed frog Silurana tropicalis. It is active against E. coli (MIC 2-4 uM), P. aeruginosa (MIC 4-8 uM), S. aureus (MIC 1 uM), M. luteus (MIC 0.5 uM), and S. cerevisiae (MIC 16 uM). CPF-St4 is also toxic to erythrocytes (HC50 64 uM) and T-lymphocytes (IC50 2 uM).
CPF-St5
CPF-St5 was found in the African clawed frog Silurana tropicalis. It exerts antimicrobial effects against Gram-positive bacteria, Gram-negative bacteria, and fungi.
CPF-St6
CPF-St6 was found in the African clawed frog Silurana tropicalis. It exerts antimicrobial effects against Gram-positive bacteria, Gram-negative bacteria, and fungi.
CPF-St7
CPF-St7 was found in the African clawed frog Silurana tropicalis. It exerts antimicrobial effects against Gram-positive bacteria, Gram-negative bacteria, and fungi.
CPFX2090
CPFX2090 is a cephalosporin antibacterial compound. Synonyms: 5-chloro-1-ethyl-3-(hydroxymethyl)-6,7-bis((4-methoxybenzyl)oxy)quinolin-4(1H)-one. CAS No. 1429439-25-7. Molecular formula: C28H28ClNO6. Mole weight: 509.98.
CPFX4158
CPFX4158 is a mannose deriviative and an antibacterial agent. Synonyms: CPFX-4158. CAS No. 1804962-84-2. Molecular formula: C51H55NO19. Mole weight: 985.99.
CPG52364
CPG52364 a small molecule toll-like receptor(TLR) antagonist, which is a type I transmembrane receptors and the central components of the innate immune system. It has recently completed phase 1 clinical trial for SLE therapy. Uses: Cpg52364 is used for the sle therapy. Synonyms: CPG-52364; CPG 52364; CPG52364; 6,7-Dimethoxy-2-(4-(4-methylpiperazin-1-yl)phenyl)-N-(2-morpholinoethyl)quinazolin-4-amine. Grade: >98%. CAS No. 1093135-60-4. Molecular formula: C27H36N6O3. Mole weight: 492.62.
CPG-52364
CPG-52364 (compound 2) is a TLR9 antagonist. CPG-52364 inhibits the HEK293-hTLR9 cell with an IC50 value of 4.6 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1093135-60-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-120538.
CPG52364 sulfate
CPG52364 sulfate is the sulfate form of CPG52364, which is a small molecule toll-like receptor(TLR) antagonist. It has recently completed phase 1 clinical trial for SLE therapy. Uses: Cpg52364 sulfate is used for the sle therapy. Synonyms: CPG-52364 sulfate; CPG 52364 sulfate; CPG52364 sulfate; 6,7-Dimethoxy-2-(4-(4-methylpiperazin-1-yl)phenyl)-N-(2-morpholinoethyl)quinazolin-4-amine sulfate. Grade: >98%. CAS No. 1093135-62-6. Molecular formula: C27H38N6O7S. Mole weight: 590.70.
c-Phenanthren-9-yl-methylamine
c-Phenanthren-9-yl-methylamine. Alternative Names: RARECHEM AL BW 0139;C-PHENANTHREN-9-YL-METHYLAMINE. CAS No. 15398-91-1. Product ID: ACM15398911. Molecular formula: C15H13N. Mole weight: 207.27. Alfa Chemistry - ISO 9001:32057 Certified.
c(phg-isoDGR-(NMe)k)
c(phg-isoDGR-(NMe)k) is a selective and potent α5β1-integrin ligand with IC50 of 2.9 nM. Grade: >98%. CAS No. 1844830-65-4. Molecular formula: C27H41N9O7. Mole weight: 603.67.
C-Phycocyanin
C-phycocyanin (C-PC) is a protein pigment which is also widely used as an excellent nutrient supplement for human beings. Uses: Scientific research. Category: Signaling pathways. Alternative Names: C-PC. CAS No. 11016-15-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1025.
C-phycocyanin α-cysteine-84 phycocyanobilin lyase
The enzyme, characterized from the cyanobacterium Synechococcus elongatus PCC 7942, catalyses the covalent attachment of the phycobilin chromophore phycocyanobilin to cysteine 84 of the α subunit of the phycobiliprotein C-phycocyanin. Group: Enzymes. Synonyms: cpcE (gene name); cpcF (gene name). Enzyme Commission Number: EC 4.4.1.32. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5335; C-phycocyanin α-cysteine-84 phycocyanobilin lyase; EC 4.4.1.32; cpcE (gene name); cpcF (gene name). Cat No: EXWM-5335.
CPI1
CPI1 is a multidrug resistance protein 1 (MRP1) inhibitor with a Ki value of 100 nM. CPI1 binds to the same substrate-binding site as leukotriene C4, stabilizes MRP1 in an apo-like inward-facing conformation, blocks the conformational changes required for ATP hydrolysis and substrate transport, and inhibits the ATPase activity of human and bovine MRP1. CPI1 serves as a tool for investigating the substrate transport mechanism of MRP1. CPI1 is applicable to research related to cancer multidrug resistance[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3085809-95-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P10856.
CPI-1189
CPI-1189 is an inhibitor of TNF-α release with the potential use to treat sciatica and postherpetic neuralgia. Synonyms: 4-Acetamido-N-tert-butylbenzamide; CPI-1189; REN-1189; REN-1654; CPI1189; REN1189; REN1654; CPI 1189; REN 1189; REN 1654. CAS No. 183619-38-7. Molecular formula: C13H18N2O2. Mole weight: 234.299.
CPI-1205
A highly potent and selective EZH2 inhibitor (biochemical IC50=2 nM, cellular EC50=32 nM). Synonyms: CPI-1205; CPI 1205; CPI1205; N-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-2-methyl-1-[(1R)-1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indole-3-carboxamide; (R)-N-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide; CPI-1205. CAS No. 1621862-70-1. Molecular formula: C27H33F3N4O3. Mole weight: 518.57.
CPI-1328
CPI-1328 is a highly potent second-generation EZH2 inhibitor with a Ki of 63 fM. Synonyms: 1,3-Dioxolo[4,5-g]isoquinolin-5(6H)-one, 9-chloro-6-[[1,2-dihydro-6-methyl-4-(methylthio)-2-oxo-3-pyridinyl]methyl]-2-[trans-4-(dimethylamino)cyclohexyl]-7,8-dihydro-2,4-dimethyl-, (2R)-; (R)-9-chloro-2-((1r,4R)-4-(dimethylamino)cyclohexyl)-2,4-dimethyl-6-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]isoquinolin-5(6H)-one; CPI1328; CPI 1328. CAS No. 2390367-27-6. Molecular formula: C28H36ClN3O4S. Mole weight: 546.12.
CPI-1612
CPI-1612 is a highly potent, orally active EP300/CBP histone acetyltransferase (HAT) inhibitor with an IC50 of 8.1 nM for EP300 HAT. CPI-1612 has an anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2374971-81-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136285.
CPI-169
CPI-169 is a novel and potent EZH2 inhibitor, it decreases cellular levels of H3K27me3 and triggers cell cycle arrest and apoptosis in a variety of cell lines. Synonyms: CPI-169; CPI 169; CPI169. Grade: >98%. CAS No. 1450655-76-1. Molecular formula: C27H36N4O5S. Mole weight: 528.66.
CPI 203
CPI 203. Group: Biochemicals. Grades: Purified. CAS No. 1446144-04-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CPI-203
CPI-203 is a BET bromodomain inhibitor. It inhibits BRD4 in vitro and in cells, and causes G1 cell cycle arrest. It also arrests the growth of T cell acute lymphoblastic leukemia cells in vitro (EC50 = 91.2 nM). Synonyms: CPI203; CPI-203; CPI 203; TEN010; TEN 010; TEN010; JQ-2; JQ 2; JQ2; RG-6146; RG 6146; RG-6146; RO6870810; RO-6870810; RO 6870810. (6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide. Grade: >98%. CAS No. 1446144-04-2. Molecular formula: C19H18ClN5OS. Mole weight: 399.90.
CPI-203
CPI-203 is a novel potent, selective and cell permeable inhibitor of BET bromodomain, with an IC50 value of appr 37 nM (BRD4 α-screen assay). Uses: Scientific research. Category: Signaling pathways. CAS No. 1446144-04-2. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15846.
CPI-268456
CPI-268456 is a ligand of bromodomain-containing protein 4 (BRD4). It binds to BRD4 and inhibits LPS-induced IL-6 secretion in THP-1 cells. Synonyms: 2-[(4S)-8-chloro-6-(4-chlorophenyl)-1-methyl-4H-[1,2]oxazolo[5,4-d][2]benzazepin-4-yl]acetamide. Grade: ≥98%. CAS No. 1380087-86-4. Molecular formula: C20H15Cl2N3O2. Mole weight: 400.3.
CPI-360
CPI-360 is a potent, selective,and SAM-competitive EZH1 inhibitor with IC50 of 102.3 nM, >100-fold selectivity over other methyltransferases. Synonyms: CPI360; CPI 360. Grade: 98%. CAS No. 1802175-06-9. Molecular formula: C25H31N3O4. Mole weight: 437.53.
CPI 4203
CPI 4203 is a selective inhibitor of KDM5 demethylases structurally related to CPI 455. Synonyms: CPI-4203; CPI 4203; CPI4203; 6-ethyl-7-oxo-5-(o-tolyl)-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile. Grade: 99%. CAS No. 1628214-07-2. Molecular formula: C16H14N4O. Mole weight: 278.31.
CPI-444
CPI-444 is a potent, orally available, selective antagonist of the adenosine A2A receptor that has been well tolerated in Ph 1/1b studies in non-oncology indications. Synonyms: (S)-7-(5-methylfuran-2-yl)-3-((6-(((tetrahydrofuran-3-yl)oxy)methyl)pyridin-2-yl)methyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-amine; CPI-444; CPI 444; CPI444; V81444; V-81444; V 81444. CAS No. 1202402-40-1. Molecular formula: C20H21N7O3. Mole weight: 407.17.
CPI 455
CPI 455 is a selective inhibitor of KDM5 demethylases (IC50 value 10 nM for inhibition of full length KDM5A) that specifically alters H3K4 methylation (H3K4me3) in vitro and reduces survival of drug-tolerant cancer cells. Uses: Antitumor agent for drug-tolerant cancer. Synonyms: CPI-455; CPI-455; CPI-455; 6-Isopropyl-7-oxo-5-phenyl-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile. Grade: 99%. CAS No. 1628208-23-0. Molecular formula: C16H14N4O. Mole weight: 278.31.
CPI-455
CPI-455 is a specific, pan-KDM5 inhibitor with an IC50 of 10 nM for KDM5A. CPI-455 mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1628208-23-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100421.
CPI-455 analogue
CPI-455 analogue is an analogue of CPI-455 which is a KDM5 inhibitor. Molecular formula: C16H14N4O. Mole weight: 278.31.
CPI-455 hydrochloride
CPI-455 is a specific inhibitor of KDM5 with IC50 of 10 ± 1 nM for full-length KDM5A in enzymatic assays. Synonyms: 7-oxo-5-phenyl-6-propan-2-yl-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile hydrochloride. Grade: ≥99%. CAS No. 2095432-28-1. Molecular formula: C16H15ClN4O. Mole weight: 314.77.
CPI-455 hydrochloride
CPI-455 hydrochloride is a specific, pan-KDM5 inhibitor with an IC50 of 10 nM for KDM5A. CPI-455 hydrochloride mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2095432-28-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-100421A.
CPI-613
CPI-613 is a racemic mixture of the enantiomers of a synthetic alpha-lipoic lipoic acid analogue with potential chemopreventive and antineoplastic activities. Although the exact mechanism of action is unknown, alpha-lipoic acid analogue CPI-613 has been shown to inhibit metabolic and regulatory processes required for cell growth in solid tumors. Both enantiomers in the racemic mixture exhibit antineoplastic activity. The mechanism-of-action of CPI-613 appears distinct from the current classes of anti-cancer agents used in the clinic. CPI-613 demonstrates both in vitro and in vivo anti-tumor activity. CPI-613 was known to strongly disrupt tumor mitochondrial metabolism. CPI-613 disruption of tumor mitochondrial metabolism is followed by efficient commitment to cell death by multiple, apparently redundant pathways, including apoptosis, in all tested cancer cell lines. Further, CPI-613 shows strong antitumor activity in vivo against human non-small cell lung and pancreatic cancers in xenograft models with low side-effect toxicity. Synonyms: CPI613; CPI 613; Devimistat; 6,8-bis(benzylthio)octanoic acid. Grade: 98%. CAS No. 95809-78-2. Molecular formula: C22H28O2S2. Mole weight: 388.59.
CPI-613 (Devimistat)
Devimistat (CPI-613), a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase in NCI-H460 cell line, disrupts tumor cell mitochondrial metabolism. CPI-613 induces apoptosis in pancreatic cancer cells. Phase 2. Group: Inhibitors. CAS No. 95809-78-2. Pack Sizes: 5mg. Product ID: S2776. Formula: C22H28O2S2. Smiles: C1=CC=C(C=C1)CSCCC(CCCCC(=O)O)SCC2=CC=CC=C2. Storage Conditions: 2 years -80 in solvent.
United States; Europe
CPI-637
CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor with IC50 of 0.03±0.01μM and 11.0±0.6 μM for CBP/EP300 and BRD4, respectively. CPI-637 displayed a >700-fold selectivity over the BET family of bromodomains (BRD4 IC50=11.0 ± 0.6 μM). Synonyms: CPI-637; CPI 637; CPI637. (4R)-4-methyl-6-[1-methyl-3-(1-methylpyrazol-4-yl)indazol-5-yl]-1,3,4,5-tetrahydro-1,5-benzodiazepin-2-one; CPI-637; SCHEMBL17673230. Grade: >98%. CAS No. 1884712-47-3. Molecular formula: C22H22N6O. Mole weight: 386.459.
CPI-637
CPI-637 is a selective and potent CBP/EP300 bromodomain inhibitor with IC50 values of 0.03 μM, 0.051 μM and 11.0 μM for CBP, EP300 and BRD4 BD-1, respectively, and an EC50 of 0.3 μM for CBP[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1884712-47-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100482.
CPK20
CPK20 is a potent and highly selective KCNT1 channel blocker, and CPK20 can be used in the study of epilepsy[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2397708-22-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162549.
CPL304110
CPL304110 is a potent, orally active and selective inhibitor of fibroblast growth factor receptors FGFR (1-3), with IC50 values of 0.75 nM, 0.5 nM, and 3.05 nM for FGFR (1-3), respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1627826-19-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-131908.
CPL304110
CPL304110 is a potent, selective and orally active fibroblast growth factor receptors FGFR (1-3) inhibitor, with IC50s of 0.75, 0.5 and 3.05 nM, respectively. Synonyms: 1H-Benzimidazole, 2-[5-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl]-6-(4-methyl-1-piperazinyl)-; 2-{5-[2-(3,5-Dimethoxyphenyl)ethyl]-1H-pyrazol-3-yl}-6-(4-methyl-1-piperazinyl)-1H-benzimidazole. Grade: ≥95%. CAS No. 1627826-19-0. Molecular formula: C25H30N6O2. Mole weight: 446.54.
CPM
CPM is a maleimide derivative, acting as a blue fluorescent thiol-reactive dye (excitation/emission maxima of 387/463 nm)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 76877-33-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0069.
CPN-219
CPN-219, a next-generation hexapeptidic NMUR2 agonist, achieves a dose-dependent and selective activation of NMUR2 with an EC50 value of 2.2 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2240202-02-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3030.
CPPG
CPPG is the most potent group II/III mGluR antagonist displaying approximately 20-fold selectivity for group III over group II (IC50 = 2.2 and 46.2 nM, respectively). Synonyms: (RS)-α-Cyclopropyl-4-phosphonophenylglycine; Cyclopropyl-4-phosphonophenylglycine; 2-amino-2-cyclopropyl-2-(4-phosphonophenyl)acetic acid. Grade: ≥98% by HPLC. CAS No. 183364-82-1. Molecular formula: C11H14NO5P. Mole weight: 271.21.
CPPG
CPPG ((RS)-CPPG) is a potent group II/III mGlu receptors antagonist. CPPG exhibits some selectivity (approximately 20 fold) for group III (IC50=2.2 nM) over group II (IC50=46.2 nM) mGlu receptors in the rat cerebral cortex. CPPG has weak effects at group I mGlu receptors[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (RS)-CPPG. CAS No. 183364-82-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-101333.
CPPG
CPPG. Group: Biochemicals. Grades: Purified. CAS No. 183364-82-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CPPHA
CPPHA. Group: Biochemicals. Grades: Purified. CAS No. 693288-97-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
CPPHA
CPPHA is a selective positive allosteric modulator of mGluR5 receptor. It is thought to act at a novel allosteric site and potentiates mGlu5 responses by a mechanism distinct from that of VU 29. Grade: >98%. CAS No. 693288-97-0. Molecular formula: C22H15ClN2O4. Mole weight: 406.82.
CPS2
CPS2 is a first-in-class, highly potent, selective and irreversible PROTAC CDK2 degrader (IC50 = 24 nM) for the study of acute myeloid leukemia. Synonyms: 4-((5-amino-1-(3-methylthiophene-2-carbonyl)-1H-1,2,4-triazol-3-yl)amino)-N-(2-((1-(2-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)ethoxy)ethyl)-1H-1,2,3-triazol-4-yl)methoxy)ethyl)benzenesulfonamide; CDK2 degrader CPS2; Benzenesulfonamide, 4-[[5-amino-1-[(3-methyl-2-thienyl)carbonyl]-1H-1,2,4-triazol-3-yl]amino]-N-[2-[[1-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethyl]-1H-1,2,3-triazol-4-yl]methoxy]ethyl]-; 4-[[5-Amino-1-[(3-methyl-2-thienyl)carbonyl]-1H-1,2,4-triazol-3-yl]amino]-N-[2-[[1-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethyl]-1H-1,2,3-triazol-4-yl]methoxy]ethyl]benzenesulfonamide. Grade: ≥95%. CAS No. 2756741-90-7. Molecular formula: C38H42N12O10S2. Mole weight: 890.94.
CPS2
CPS2 is a first-in-class, highly potent, selective and irreversible PROTAC CDK2 degrader (IC50= 24 nM). CPS2 can be used for the research of acute myeloid leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2756741-90-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141680.
CPT 11
CPT 11. Group: Biochemicals. Grades: Purified. CAS No. 100286-90-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CPT-157633
CPT-157633, a difluoro-phosphonomethyl phenylalanine derivative, and is a PTP1B inhibitor. CPT-157633 prevents binge drinking-induced glucose intolerance[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 888213-72-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111469.
CPTH2 is a histone acetyltransferase (HAT) inhibitor modulating Gcn5p network in vitro and in vivo. HAT is an enzyme playing an important role in histone acetylation and multiple cancer development. Uses: Antitumor agent. Synonyms: CPTH2; CPTH 2; CPTH-2; Cyclopentylidene-[4-(4-chlorophenyl)thiazol-2-yl)hydrazone. Grade: 99%. CAS No. 357649-93-5. Molecular formula: C14H14ClN3S. Mole weight: 291.8.
CPTH2
CPTH2 is a potent histone acetyltransferase (HAT) inhibitor. CPTH2 selectively inhibits the acetylation of histone H3 by Gcn5. CPTH2 induces apoptosis and decreases the invasiveness of a clear cell renal carcinoma (ccRCC) cell line through the inhibition of acetyltransferase p300 (KAT3B)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 357649-93-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-W013274.
CPTH2
CPTH2 is a histone acetyltransferase inhibitor that modulates Gcn5p dependent functional network in vitro and in vivo. Group: Biochemicals. Alternative Names: 2-[4-(4-Chlorophenyl)-2-thiazolyl]hydrazone-cyclopentanone; 4- (4-Chlorophenyl) -2 (3H) -thiazolone-cyclopentylidene hydrazone. Grades: Highly Purified. CAS No. 357649-93-5. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
CPTH2 hydrochloride
Gcn5 is a chromatin modifying factor that has HAT activity to acetylate histone H3 lysine 9 (K9) and K14. CPTH2 inhibits the HAT activity of Gcn5. It is used to study the influence of Gcn5-dependent acetylation in various biological systems. Synonyms: 2-[4-(4-chlorophenyl)-2-thiazolyl]hydrazone-cyclopentanone monohydrochloride. Grade: ≥95%. CAS No. 2108899-91-6. Molecular formula: C14H14ClN3S·HCl. Mole weight: 328.3.
CPTH6 hydrobromide
CPTH6 is a thiazole derivative structurally and it can inhibit the lysine acetyltransferase activity of Gcn5 and pCAF but not p300 or CBP. Synonyms: 3-methyl-2-[4-(4-chlorophenyl)-2-thiazolyl]hydrazone cyclopentanone hydrobromide. Grade: ≥98%. CAS No. 2321332-57-2. Molecular formula: C15H16ClN3S·HBr. Mole weight: 386.7.
Cp-thionin II
Cp-thionin II is a novel gamma-thionin from cowpea seeds (Vigna unguiculata) with bactericidal activity against Gram-positive and Gram-negative bacteria.
CPUY074020
CPUY074020 is a potent and orally bioavailable histone methyltransferase G9a inhibitor (IC50 = 2.18 μM), with anti-proliferative activity. Synonyms: 3-(1-Piperidyl)-5-[[2-(1-pyrrolidinyl)ethyl]amino]-6H-anthra[1,9-cd]isoxazol-6-one; 6H-Anthra[1,9-cd]isoxazol-6-one, 3-(1-piperidinyl)-5-[[2-(1-pyrrolidinyl)ethyl]amino]-; 3-piperidin-1-yl-5-[(2-pyrrolidin-1-ylethyl)amino]-6H-anthra[1,9-cd]isoxazol-6-one. Grade: ≥95%. CAS No. 902279-44-1. Molecular formula: C25H28N4O2. Mole weight: 416.52.
CPUY192018
CPUY192018 is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, with an IC50 of 0.63 μM. CPUY192018 exhibits anti-inflammatory and antioxidant activities. CPUY192018 can activate the Nrf2-dependent antioxidant pathway and inhibit the NF-κB-related inflammatory response. CPUY192018 can be used in the research of inflammation-related diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1567836-15-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120371.
CPUY201112
CPUY201112 is an N-terminal Hsp90 inhibitor, which leads to decreased expression of Hsp90 client proteins and may result in increased tumor cell apoptosis. Synonyms: CPUY201112; CPUY 201112; CPUY-201112. Grade: >98%. CAS No. 1860793-58-3. Molecular formula: C19H23N3O4. Mole weight: 357.41.
CPVC
CPVC. CAS No. 68648-82-8.
CPVC Resin
CPVC Resin.
CPYPP
CPYPP has been found to be a DOCK2-Rac1 interaction inhibitor and could probably attenuate HER2-mediated breast cancer cell migration. Synonyms: 4-[3-(2-Chlorophenyl)-2-propen-1-ylidene]-1-phenyl-3,5-pyrazolidinedione. Grade: ≥98% by HPLC. CAS No. 310460-39-0. Molecular formula: C18H13ClN2O2. Mole weight: 324.76.
CPYPP
CPYPP is a DOCK2-Rac1 interaction inhibitor. CPYPP binds to DOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2DHR-2 for Rac1 in a dose-dependent manner with an IC50 of 22.8 μM. CPYPP also inhibits DOCK180 and DOCK5 and less inhibits DOCK9[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 310460-39-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110100.
CPZEN-45
CPZEN-45 exhibits potent antibacterial activity against several DS, as well as MDR and XDR strains of Mtb in murine models and exhibits synergistic effects with other TB drugs. Synonyms: Caprezene-4-butylanilide; (2S)-2-[(S)-[(2S,3R,4S,5R)-5-(aminomethyl)-3,4-dihydroxy-tetrahydrofuran-2-yl]oxy-[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl]-N-(4-butylphenyl)-1,4-dimethyl-3-oxo-2,7-dihydro-1,4-diazepine-5-carboxamide. Molecular formula: C32H44N6O11. Mole weight: 688.72.