A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
CT-721 is a potent and time-dependent inhibitor of Bcr-Abl kinase with an IC50 of 21.3 nM for wild-type Bcr-Abl kinase, and has anti-chronic myeloid leukemia (CML) activity. Synonyms: (1S)-N-{3-[(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methylphenyl}-1-(4-methyl-1-piperazinyl)-5-indanecarboxamide; 1H-Indene-5-carboxamide, N-[3-[2-(6-chloroimidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methylphenyl]-2,3-dihydro-1-(4-methyl-1-piperazinyl)-, (1S)-. Grade: ≥98%. CAS No. 1388710-60-8. Molecular formula: C30H29ClN6O. Mole weight: 525.04.
CT-996
CT-996 is an orally active GLP-1RA agonist with an EC50 of 0.49 nM. CT-996 reduces the recruitment of β-arrestin and the internalization of GLP-1R. CT-996 suppresses postprandial blood glucose in mice expressing human GLP-1 receptors and enhances glucose-stimulated insulin secretion (GSIS) in obese monkeys during intravenous glucose challenge. CT-996 can be used for the research of type 2 diabetes (T2D) and obesity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RO7795081; RG6652. CAS No. 2810808-95-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-175701.
CTA056
CTA056 is a potent and selective ITK inhibitor (interleukin-2-inducible T-cell kinase inhibitor). ITK is a member of the Btk (Bruton's tyrosine kinase) family of tyrosine kinases, plays an important role in normal T-cell functions and in the pathophysiology of both autoimmune diseases and T-cell malignancies. CTA056 exhibits the highest inhibitory effects toward Itk, followed by Btk and endothelial and epithelial tyrosine kinase. Among the 41 cancer cell lines analyzed, CTA056 selectively targets acute lymphoblastic T-cell leukemia and cutaneous T-cell lymphoma. CTA056 may be potential therapeutic agent for the treatment of T-cell leukemia and lymphoma. Synonyms: CTA-056; CTA 056; 1,5-Dihydro-7-(phenylmethyl)-1-[3-(1-piperidinyl)propyl]-2-[4-(4-pyridinyl)phenyl]-6H-imidazo[4,5-g]quinoxalin-6-one. Grade: 98%. CAS No. 1265822-30-7. Molecular formula: C35H34N6O. Mole weight: 554.69.
Ct-AMP1
HGAPDH is a plant defensin isolated from Clitoria ternatea. It has activity against gram-positive bacteria and fungi. Synonyms: Asn-Leu-Cys-Glu-Arg-Ala-Ser-Leu-Thr-Trp-Thr-Gly-Asn-Cys-Gly-Asn-Thr-Gly-His-Cys-Asp-Thr-Gln-Cys-Arg-Asn-Trp-Glu-Ser-Ala-Lys-His-Gly-Ala-Cys-His-Lys-Arg-Gly-Asn-Trp-Lys-Cys-Phe-Cys-Tyr-Phe-Asp-Cys. Molecular formula: C234H344N76O71S8. Mole weight: 5614.25.
CTAP
CTAP is a potent, highly selective, and BBB penetrant μ opioid receptor antagonist, with an IC50 of 3.5 nM. CTAP displays over 1200-fold selectivity over δ opioid (IC50=4500 nM) and somatostatin receptors. CTAP can be used for the study of L-DOPA-induced dyskinesia (LID) and opiate overdose or addiction[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 103429-32-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1335.
CTAP
CTAP has been found to be a selective μ-opioid receptor antagonist. Synonyms: D-Phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-arginyl-L-threonyl-3-mercapto-L-valyl-L-threoninamide cyclic (2→7)-disulfide. Grade: ≥95% by HPLC. CAS No. 103429-32-9. Molecular formula: C51H69N13O11S2. Mole weight: 1104.32.
CTAP
CTAP. Group: Biochemicals. Grades: Purified. CAS No. 103429-32-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CTAP (Mu Opioid Receptor Antagonist, CTAP)
A highly potent octapeptide that acts as a selective and brain penetrating bioavailable u opioid receptor antagonist (IC50 = 3.5nM). Used in studies of reward systems and additions. Group: Biochemicals. Grades: Highly Purified. CAS No. 103429-32-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CTAP TFA
CTAP TFA is a potent brain penetrant μ opioid receptor antagonist (IC50 = 3.5 nM) and displays over 1200-fold selectivity over δ opioid (IC50 = 4500 nM) and somatostatin receptors. Synonyms: Cys2, Tyr3, Arg5, Pen7-Amide TFA. Grade: 99%. Molecular formula: C53H70F3N13O13S2. Mole weight: 1218.32.
CTAP trifluoroacetate salt
CTAP is a water-soluble and selective antagonist of the μ opioid receptor (IC50 = 3.5 nM) over the δ receptor (IC50 = 4,500 nM). It is a cyclic octapeptide which acts as a poor antagonist of the somatostatin receptor (IC50 = 14.3 μM). CTAP is at least 10-fold more potent than naltrexone. Molecular formula: C51H69N13O11S2·xCF3COOH. Mole weight: 1104.31.
CTB
CTB is a p300 histone acetyltransferase activator. Synonyms: CTPB; N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide. CAS No. 451491-47-7. Molecular formula: C16H13ClF3NO2. Mole weight: 343.73.
CTB
CTB is a potent p300 histone acetyltransferase activator[1]. CTB can effectively induce apoptosis in MCF-7 cells[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 451491-47-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134964.
CTCE-0214
CTCE-0214 is a chemokine CXC receptor 4 (CXCR4) agonist, SDF-1α (stromal cell-derived factor-1α) peptide analog. CTCE-0214 shows anti-inflammatory activity, and can be used in inflammation sepsis and systemic inflammatory syndromes research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 577782-52-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3612.
CTCE 9908
It is a CXCR4 antagonist that induces mitotic catastrophe in ovarian cancer cells. Synonyms: L-Lysinamide, N2,N6-bis(L-lysylglycyl-L-valyl-L-seryl-L-leucyl-L-seryl-L-tyrosyl-L-arginyl)-; CTCE-9908; CTCE9908; H-Lys-Gly-Val-Ser-Leu-Ser-Tyr-Arg-Lys(1)-NH2.H-Lys-Gly-Val-Ser-Leu-Ser-Tyr-Arg-(1). Grade: >98%. CAS No. 1030384-98-5. Molecular formula: C86H147N27O23. Mole weight: 1927.27.
CTCE 9908
CTCE 9908. Group: Biochemicals. Grades: Purified. CAS No. 1030384-98-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
C-telopeptide
C-telopeptide, also called as CTX, is a cross-linked peptide of type I collagen and an RIA based on monoclonal antibody raised against this 8-amino-acid sequence was developed. C-telopeptide is released during bone resorption and has been correlated with bone mineral density (BMD). Synonyms: H-Glu-Lys-Ala-His-Asp-Gly-Gly-Arg-OH; L-alpha-glutamyl-L-lysyl-L-alanyl-L-histidyl-L-alpha-aspartyl-glycyl-glycyl-L-arginine; (2S,11S,14S,17S,20S,23S)-14-((1H-imidazol-4-yl)methyl)-23-amino-20-(4-aminobutyl)-11-(carboxymethyl)-2-(3-guanidinopropyl)-17-methyl-4,7,10,13,16,19,22-heptaoxo-3,6,9,12,15,18,21-heptaazahexacosane-1,26-dioic acid; CTX. Grade: ≥95%. CAS No. 162929-64-8. Molecular formula: C34H56N14O13. Mole weight: 868.89.
C-telopeptide acetate
C-telopeptide, also called as CTX, is a cross-linked peptide of type I collagen. C-telopeptide is released during bone resorption and has been correlated with bone mineral density (BMD). Synonyms: CTX acetate. Molecular formula: C36H60N14O15. Mole weight: 928.95.
CTEP
CTEP is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor (IC50=2.2 nM), showing >1000-fold selectivity over other mGlu receptors. Synonyms: RO4956371; RO-4956371; RO 4956371; CTEP. Grade: >98%. CAS No. 871362-31-1. Molecular formula: C19H13ClF3N3O. Mole weight: 391.77.
CTEP
CTEP (RO 4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, and shows > 1000-fold selectivity over other mGlu receptors. CTEP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RO 4956371; mGluR5 inhibitor. CAS No. 871362-31-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15445.
C-terminal processing peptidase
Proteolytic processing of the D1 protein of photosystem II is necessary to allow the light-driven assembly of the tetranuclear manganese cluster, which is responsible for photosynthetic water oxidation. The recognition of the substrate is mediated by a PDZ domain, a small protein module that promotes protein-protein interactions by binding to internal or C-terminal sequences of their partner proteins. Type example of peptidase family S41. Group: Enzymes. Synonyms: CtpA gene product (Synechocystis sp.); photosystem II D1 protein processing peptidase; protease Re; tail-specific protease; Tsp protease. Enzyme Commission Number: EC 3.4.21.102. CAS No. 216484-75-2, 92480-11-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4097; C-terminal processing peptidase; EC 3.4.21.102; 216484-75-2, 92480-11-0; CtpA gene product (Synechocystis sp.); photosystem II D1 protein processing peptidase; protease Re; tail-specific protease; Tsp protease. Cat No: EXWM-4097.
CTK8A3536 is an androgen receptor inhibitor. Synonyms: 5-Thiazolemethanol, 2-(4-morpholinyl)-4-phenyl-; 2-(4-Morpholinyl)-4-phenyl-5-thiazolemethanol; [2-(Morpholin-4-yl)-4-phenyl-1,3-thiazol-5-yl]methanol; (2-morpholino-4-phenylthiazol-5-yl)methanol; Androgen receptor-IN-3; CTK-8A3536, CTK 8A3536. Grade: ≥95%. CAS No. 926228-58-2. Molecular formula: C14H16N2O2S. Mole weight: 276.35.
CTLA-4 inhibitor
CTLA-4 inhibitor is an inhibitor of CTLA-4, an immune checkpoint negatively regulating T cell function. CTLA-4 is thought to regulate T-cell proliferation early in an immune response, primarily in lymph nodes. Synonyms: MDK24720; MDK 24720; MDK-24720; CTLA-4 inhibitor. 2-(4-Fluorophenyl)-6-methyl-4-(3-(trifluoromethyl)phenyl)-1,2-dihydrodipyrazolo[3,4-b:3',4'-d]pyridin-3(6H)-one; EX-A913. CAS No. 635324-72-0. Molecular formula: C21H13F4N5O. Mole weight: 427.363.
cTMP
cTMP (2?,3?-dideoxy-3?-thiothymidine) is an exceptional biomedical compound ubiquitously applied in studying the pernicious Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS). Functioning as a high-potency antiretroviral compound, cTMP exercises its efficacious mechanism by adeptly obstructing the pernicious reverse transcriptase enzyme. Synonyms: Thymidine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. CAS No. 76567-90-3. Molecular formula: C10H12N2O7P · Na. Mole weight: 326.2.
CTNNB1 (29-37)
CTNNB1 anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Synonyms: Catenin Beta 1 (29-37).
CTOP
CTOP has been found to be an effective and selective μ opioid receptor antagonist and could be used in the treatment of pain. Synonyms: D-Phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-ornithyl-L-threonyl-3-mercapto-L-valyl-L-threoninamide Cyclic (2→7)?-Disulfide. Grade: 98%. CAS No. 103429-31-8. Molecular formula: C50H67N11O11S2. Mole weight: 1062.28.
CTOP
CTOP. Group: Biochemicals. Grades: Purified. CAS No. 103429-31-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CTOP (Mu Opioid Receptor Antagonist, CTOP)
A potent antagonist highly selective for Mu opioid receptor (Ki = 0.96nM for u receptor and > 10,000nM for delta receptors). Often used for studying the functional roles of Mu opioid receptors in both central and peripheral nervous systems. Group: Biochemicals. Grades: Highly Purified. CAS No. 103429-31-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CTOP trifluoroacetate salt
CTOP is a peptide that acts as a selective antagonist of the μ-opioid receptor (IC50 = 2.8 nM). CTOP inhibits the antinociceptive effect of morphine in the tail flick test in mice (ED50 = 0.018 nmol) and reverses morphine-induced increases in locomotor activity (ED50 = 0.02 nmol). Synonyms: Phe-Cys-Tyr-Trp-Orn-Thr-Pen-Thr; D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-ornithyl-L-threonyl-3-mercapto-L-valyl-L-threoninamide-cyclic (2→7)-disulfide trifluoroacetate salt. Grade: ≥98%. Molecular formula: C50H67N11O11S2·xCF3COOH. Mole weight: 1062.3 (free base).
CTP
CTP (cardiac targeting peptide) can transduce cardiomyocytes in vitro. CTP leads to efficient and specific transduction of heart tissue in mice model. CTP can be reversibly linked (e.g. via enolases, thiol groups) to cargo (e.g. miRNAs) for delivery specifically to cardiomyocytes over all other organs[1][2]. Uses: Scientific research. Category: Peptides. Alternative Names: Cardiac targeting peptide. CAS No. 1052692-86-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P4094.
CTP, 100mM Sodium Solution
The solution form of CTP. CTP is a P2X purinergic receptor agonist that can be used in the synthesis of RNA. In metabolic reactions, it acts as a coenzyme. Synonyms: Cytidine 5'-triphosphate, Sodium salt. Grade: ≥ 99% by HPLC. Molecular formula: C9H16N3O14P3 (free acid). Mole weight: 483.16 (free acid).
CTP-347
CTP-347 is a labelled analogue of Paroxetine. CTP-347 was developed for the treatment of hot flashes yet the phase I clinical trial was halted in 2013. Synonyms: Paroxetine-d2. CAS No. 923932-43-8. Molecular formula: C19H18D2FNO3. Mole weight: 331.38.
CTPαS TEA salt
CTPαS, a molecule activator of soluble guanylate cyclase (sGC), is vying for a preeminent position in the study of nitric oxide signaling pathway. With its therapeutic potential locked and loaded, CTPαS is turning heads in the scientific community, demonstrating potential efficacy in addressing cardiovascular diseases such as hypertension and pulmonary arterial hypertension, as well as a wide range of central nervous system conditions, including neurodegenerative diseases and pain management alike. Synonyms: Cytidine, 5'→P''-ester with thiotriphosphoric acid TEA salt; Cytidine-5'-O-(1-thiotriphosphate) TEA salt; CTP-αS TEA salt; Cytidine-5'-(α-thio)-triphosphate, TEA salt (1:1 Mixture of Rp and Sp isomers). Grade: ≥95% by HPLC. Molecular formula: C9H16N3O13P3S (free acid). Mole weight: 499.21 (free acid).
CTPB
CTPB is an amide derivative that acts as a selectively activator of the histone acetyltransferase (HAT) p300, with maximal activation at 275 μM. Synonyms: N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxy-6-pentadecyl-benzamide. Grade: ≥98%. CAS No. 586976-24-1. Molecular formula: C31H43ClF3NO2. Mole weight: 554.1.
CTPB
CTPB is a good activator of p300 histone acetyl transferase (HAT) enzyme[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 586976-24-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124960.
CTP-Cys
CTP-Cys is a cysteine attached to CTP (HY-P4094) for peptide conjugation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2300065-35-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P11541.
CTP-dependent riboflavin kinase
This archaeal enzyme differs from EC 2.7.1.26, riboflavin kinase, in using CTP as the donor nucleotide. UTP, but not ATP or GTP, can also act as a phosphate donor but it is at least an order of magnitude less efficient than CTP. Group: Enzymes. Synonyms: Methanocaldococcus jannaschii Mj0056; Mj0056. Enzyme Commission Number: EC 2.7.1.161. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2991; CTP-dependent riboflavin kinase; EC 2.7.1.161; Methanocaldococcus jannaschii Mj0056; Mj0056. Cat No: EXWM-2991.
CTP-γ-AmNS is a fluorescent analogue of CTP that is used for the determination of enzymes specialized to cleave α/β-phosphodiester bonds. Synonyms: Cytidine- 5'- O- triphosphoro- γ- 1- (5- sulfonic acid)naphthylamidate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 84230-52-4. Molecular formula: C19H23N4O16P3S (free acid). Mole weight: 688.4 (free acid).
CTPI-2
CTPI-2 is the third-generation mitochondrial citrate carrier SLC25A1 inhibitor with a KD of 3.5 μM. Synonyms: SLC25A1 Inhibitor CTPI-2; Benzoic Acid, 2-[[(4-Chloro-3-Nitrophenyl)Sulfonyl]Amino]-; 2-[(4-Chloro-3-Nitrophenyl)Sulphonyl]Anthranilic Acid. Grade: 98%. CAS No. 68003-38-3. Molecular formula: C13H9ClN2O6S. Mole weight: 356.74.
CTPI-2
CTPI-2 is a third-generation mitochondrial citrate carrier SLC25A1 inhibitor with a KD of 3.5 μM. CTPI-2 inhibits glycolysis, PPARγ, and its downstream target the glucose transporter GLUT4. CTPI-2 halts salient alterations of NASH reverting steatosis, preventing the evolution to steatohepatitis, reducing inflammatory macrophage infiltration in the liver and adipose tissue, and starkly mitigating obesity induced by a high-fat diet. Antitumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 68003-38-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg. Product ID: HY-123986.
CTP inhibitor
CTP inhibitor (Compound 792949) is a potent and selective CTP inhibitor. CTP inhibitor inhibits the plasma membrane citrate transporter (PMCT)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 412940-35-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101998.
CTP - lyophilized
The lyophilized form of CTP. CTP is a P2X purinergic receptor agonist that can be used in the synthesis of RNA. In metabolic reactions, it acts as a coenzyme. Synonyms: Cytidine 5'-triphosphate, Disodium salt trihydrate. Grade: ≥ 95% by HPLC. Molecular formula: C9H14N3Na2O14P3* 3H2O. Mole weight: 581.16.
CTP Synthase (Crude Enzyme)
This product with the indicated enzyme activity was briefly purified from engineered E.coli. Applications: Analysis; drug development; medicine. Group: Enzymes. Synonyms: UTP-ammonia ligase; cytidine triphosphate synthetase; uridine triphosphate aminase; cytidine 5'-triphosphate synthetase; CTPS (gene name); pyrG (gene name); CTP synthase; UTP:ammonia ligase (ADP-forming). Enzyme Commission Number: EC 6.3.4.2. CAS No. 9023-56-7. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. UTP-ammonia ligase; cytidine triphosphate synthetase; uridine triphosphate aminase; cytidine 5'-triphosphate synthetase; CTPS (gene name); pyrG (gene name); CTP synthase; UTP:ammonia ligase (ADP-forming). Pack: 100ml. Cat No: NATE-1862.
CTP synthase (glutamine hydrolysing)
The enzyme contains three functionally distinct sites: an allosteric GTP-binding site, a glutaminase site where glutamine hydrolysis occurs (cf. EC 3.5.1.2, glutaminase), and the active site where CTP synthesis takes place. The reaction proceeds via phosphorylation of UTP by ATP to give an activated intermediate 4-phosphoryl UTP and ADP. Ammonia then reacts with this intermediate generating CTP and a phosphate. The enzyme can also use ammonia from the surrounding solution. Group: Enzymes. Synonyms: UTP-ammonia ligase; cytidine triphosphate synthetase; uridine triphosphate aminase; cytidine 5'-triphosphate synthetase; CTPS (gene name); pyrG (gene name); CTP synthase; UTP:ammonia ligase (ADP-forming). Enzyme Commission Number: EC 6.3.4.2. CAS No. 9023-56-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5789; CTP synthase (glutamine hydrolysing); EC 6.3.4.2; 9023-56-7; UTP-ammonia ligase; cytidine triphosphate synthetase; uridine triphosphate aminase; cytidine 5'-triphosphate synthetase; CTPS (gene name); pyrG (gene name); CTP synthase; UTP:ammonia ligase (ADP-forming). Cat No: EXWM-5789.
CTP Synthetase-IN-1
CTP Synthetase-IN-1 is a potent, orally active cytidine 5'-triphosphate synthetase (CTPS) inhibitor with IC50s of 32 nM and 18 nM for human CTPS1 and human CTPS2, respectively. CTP Synthetase-IN-1 has anti-inflammatory effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2338811-71-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152149.
CTR/AMYR modulator-1
CTR/AMYR modulator-1 is a calcitonin receptor/amylin receptor modulator. CTR/AMYR modulator-1 can be used for the research of metabolic disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3097482-67-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-179738.
CTS-1027
CTS-1027 is a potent small molecule inhibitor of MMPs, with IC50s of 0.3 nM, 0.5 nM for MMP2, MMP13, respectively, and has > 1,000 fold selectivity over MMP1. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro 1130830; RS 130830. CAS No. 193022-04-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10398.
CTS-1027
CTS-1027 inhibits individual members of the MMP family that are believed to be important in inflammation and tissue damage. CTS-1027 was specifically designed, however, not to inhibit MMP 1, as inhibition of MMP 1 was believed to be associated with musculoskeletal side effects. Synonyms: RS 130830; Ro 1130830; CTS1027; CTS 1027; RS130830; Ro1130830; RS-130830; Ro-1130830. Grade: >98%. CAS No. 193022-04-7. Molecular formula: C19H20ClNO6S. Mole weight: 425.88.
CTS-21166
CTS-21166, the selective BACE1 inhibitor whose structure is not revealed, reduce brain Aβ levels by over 35% and plaque load by 40%. Phase 1 IC50=1.2-3.6 nM (cell line details NA) APP transgenic mice, 4mg/kg i.p. injection for 6 weeks, >35% ↓ brain Aβ, 40% ↓ plaque load. Human patients, 7.5.225 mg i.v. injection dose-dependant ↓ plasma Aβ, 80% ↓ at 225 mg. Synonyms: ATG-Z1; CTS-21166; ZPQ-21166; ATG Z1; CTS 21166; ZPQ 21166; ATGZ1; CTS21166; ZPQ21166. Molecular formula: none.
CT Series Talc
CT Industrial Talcs can be used in a wide range of industrial and specialty applications. CT Industrial Talcs are produced from an extensive depositof high quality platy talc ore. CT series talcs are a cost effective formulating tool for moderate brightness applications. Pack Sizes Available: 50 lbs bags, 2,000 lbs pallets.
AG&P Mineral Purveyors
CTTHWGFTLC, CYCLIC acetate
CTTHWGFTLC, CYCLIC acetate is a cyclic peptide inhibitor for matrix metalloproteinases (MMP-2) and MMP-9. Synonyms: L-Cysteine, L-cysteinyl-L-threonyl-L-threonyl-L-histidyl-L-tryptophylglycyl-L-phenylalanyl-L-threonyl-L-leucyl-, cyclic (1→10)-disulfide acetate; CTT 1 acetate; H-Cys-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys-OH.CH3CO2H (Disulfide Bridge: Cys1-Cys10); L-cysteinyl-L-threonyl-L-threonyl-L-histidyl-L-tryptophyl-glycyl-L-phenylalanyl-L-threonyl-L-leucyl-L-cysteine (1->10)-disulfide acetic acid acetate. Grade: ≥95%. Molecular formula: C54H75N13O16S2. Mole weight: 1226.39.
CTX-0294885
CTX-0294885 is a novel broad-spectrum kinase inhibitor. CTx-0294885 exhibits inhibitory activity against a broad range of kinases in vitro. Use of a quantitative proteomics approach confirmed the selectivity of CTx-0294885-bound beads for kinase enrichment. Large-scale CTx-0294885-based affinity purification followed by LC-MS/MS led to the identification of 235 protein kinases from MDA-MB-231 cells, including all members of the AKT family that had not been previously detected by other broad-spectrum kinase inhibitors. CTx-0294885 represents a powerful new reagent for analysis of kinome signaling networks that may facilitate development of targeted therapeutic strategies. Synonyms: CTX 0294885; CTX0294885; Benzamide, 2-[[5-chloro-2-[[4-(1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methyl-. Grade: 98%. CAS No. 1439934-41-4. Molecular formula: C22H24ClN7O. Mole weight: 437.93.
CTX-0294885
CTX-0294885 is a broad spectrum kinase inhibitor that can capture 235 kinases from MDA-MB-231 cells, and can capture all members of the AKT family. CTX-0294885 is a powerful reagent for analysis of kinome signaling networks that can be used for the research of diseases like inflammation, diabetes, and cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1439934-41-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15985.
CTX-0294885 hydrochloride
CTX-0294885 hydrochloride is the hydrochloride salt of CTX-0294885 which displays high affinity toward an extensive range of kinases. The evaluation of the binding profile of CTx-0294885 in MDA-MB-231 cells by quantitative MS demonstrated its selective properties as a kinase enrichment reagent. Synonyms: 2-[[5-chloro-2-(4-piperazin-1-ylanilino)pyrimidin-4-yl]amino]-N-methylbenzamide; hydrochloride; CTX-0294885 hydrochloride; CTX 0294885 hydrochloride; CTX0294885 hydrochloride. Molecular formula: C22H25Cl2N7O. Mole weight: 474.39.
C-Type Natriuretic Peptide (1-53), human
C-Type Natriuretic Peptide (1-53), human is the 1-53 fragment of C-Type Natriuretic Peptide, which belong to the natriuretic peptide family and is involved in the maintenance of electrolyte-fluid balance and vascular tone. Synonyms: CNP-53 (human); Asp-Leu-Arg-Val-Asp-Thr-Lys-Ser-Arg-Ala-Ala-Trp-Ala-Arg-Leu-Leu-Gln-Glu-His-Pro-Asn-Ala-Arg-Lys-Tyr-Lys-Gly-Ala-Asn-Lys-Lys-Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys (Disulfide bond). Grade: ≥95%. CAS No. 141294-77-1. Molecular formula: C251H417N81O71S3. Mole weight: 5801.77.
C-Type Natriuretic Peptide-22 (human, porcine, rat) trifluoroacetate salt
C-Type natriuretic peptide-22 is an endogenous peptide which has diverse biological activities. CNP-22 acts as a selective agonist of natriuretic peptide receptors (NPRs) 2 and 3 (Kds = 7, 10.8, and >500,000 pM for NPR2, 3, and 1, respectively). The 22 amino acid sequence corresponds to residues 105-126 of its precursors prepro CNP, pro CNP, and CNP-53. Synonyms: CNP-22; glycyl-L-leucyl-L-seryl-L-lysylglycyl-L-cysteinyl-L-phenylalanylglycyl-L-leucyl-L-lysyl-L-leucyl-L-α-aspartyl-L-arginyl-L-isoleucylglycyl-L-seryl-L-methionyl-L-serylglycyl-L-leucylglycyl-L-cysteine cyclic (6→22)-disulfide trifluoroacetate salt. Grade: ≥95%. Molecular formula: C93H157N27O28S3·xCF3COOH. Mole weight: 2197.60.
C-Type Natriuretic Peptide (CNP) (1-22), human
C-type natriuretic peptide is an endogenous peptide found in plasma and cerebrospinal fluid. It is composed of 22 amino acids. C-type natriuretic peptide acts as an agonist of natriuretic peptide receptor NPR2 (NPRB) and exhibits affinity for NPR3 (NPRC). It inhibits L-type calcium currents in myocytes and exhibits antiproliferative effects in cardiac fibroblasts in vitro. Regulates cartilage homeostasis, body fluid volume and exhibits vasodilatory activity in vivo. Synonyms: H-Gly-Leu-Ser-Lys-Gly-Cys(1)-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys(1)-OH; glycyl-L-leucyl-L-seryl-L-lysyl-glycyl-L-cysteinyl-L-phenylalanyl-glycyl-L-leucyl-L-lysyl-L-leucyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-glycyl-L-seryl-L-methionyl-L-seryl-glycyl-L-leucyl-glycyl-L-cysteine (6->22)-disulfide; Natriuretic peptide, C-type; C-type natriuretic peptide (1-22) (human, rat, swine); Atriopeptin C (pig); C-Type Natriuretic Peptide (32-53) (human, porcine, rat). Grade: ≥95%. CAS No. 127869-51-6. Molecular formula: C93H157N27O28S3. Mole weight: 2197.60.
C-Type Natriuretic Peptide (CNP) (1-22), human
C-Type Natriuretic Peptide (CNP) (1-22), human, a 1-22 fragment of CNP, is a natriuretic peptide receptor B (NPR-B) agonist. C-Type Natriuretic Peptide (CNP) (1-22), human inhibits cAMP synthesis stimulated by the physiological agonists histamine and 5-HT or directly by Forskolin. CNP is a potent, endothelial-derived relaxant and growthinhibitory factor[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 127869-51-6. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P1237.
C-Type Natriuretic Peptide (CNP) (1-22), human TFA
C-Type Natriuretic Peptide (CNP) (1-22), human (TFA),a 1-22 fragment of CNP, is a natriuretic peptide receptor B (NPR-B) agonist. C-Type Natriuretic Peptide (CNP) (1-22), human (TFA) inhibits cAMP synthesis stimulated by the physiological agonists histamine and 5-HT or directly by Forskolin. CNP is a potent, endothelial-derived relaxant and growthinhibitory factor[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1966153-17-2. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P1237A.
Cu
Cu. CAS No. 20427-59-2. Mole weight: 97.56068 g/mol. Purity: 99.5%.
Cu
Cu. Purity: 99.8% (metal basis).
CU-115
CU-115 is a selective TLR8 inhibitor with IC50 of 1.04 μM. CU-115 was demonstrated that inhibits ssRNA-sensing pathways at low concentrations and does not inhibit other non-endosomal TLR and cytosolic NA-sensing pathways (<5 μ M). Synonyms: N-(4-(3,5-Bis(trifluoromethyl)phenoxy)phenyl)-2-fluoro-6-iodobenzamide. Grade: 98%. CAS No. 2471982-20-2. Molecular formula: C21H11F7INO2. Mole weight: 569.21.
Cu2+-exporting ATPase
A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. The enzyme from the termophilic bacterium Archaeoglobus fulgidus is involved in copper extrusion from the cell. Group: Enzymes. Synonyms: CopB. Enzyme Commission Number: EC 3.6.3.4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4678; Cu2+-exporting ATPase; EC 3.6.3.4; CopB. Cat No: EXWM-4678.
CU-32
CU-32 is an inhibitor of cyclic GMP-AMP (cGAMP) synthase (IC50 = 0.45 μM). Synonyms: methyl 4-amino-6-((4-iodophenyl)amino)-1,3,5-triazine-2-carboxylate. Grade: 95%. CAS No. 2400954-16-5. Molecular formula: C11H10IN5O2. Mole weight: 371.13.
CU-76
An inhibitor of cyclic GMP-AMP synthase (IC50 = 0.24 μM). Synonyms: Methyl 4-amino-6-((3,5-difluoro-4-iodophenyl)amino)-1,3,5-triazine-2-carboxylate. Grade: 95%. CAS No. 2400954-58-5. Molecular formula: C11H8F2IN5O2. Mole weight: 407.11.
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