A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
CTPI-2 is the third-generation mitochondrial citrate carrier SLC25A1 inhibitor with a KD of 3.5 μM. Synonyms: SLC25A1 Inhibitor CTPI-2; Benzoic Acid, 2-[[(4-Chloro-3-Nitrophenyl)Sulfonyl]Amino]-; 2-[(4-Chloro-3-Nitrophenyl)Sulphonyl]Anthranilic Acid. Grade: 98%. CAS No. 68003-38-3. Molecular formula: C13H9ClN2O6S. Mole weight: 356.74.
CTPI-2
CTPI-2 is a third-generation mitochondrial citrate carrier SLC25A1 inhibitor with a KD of 3.5 μM. CTPI-2 inhibits glycolysis, PPARγ, and its downstream target the glucose transporter GLUT4. CTPI-2 halts salient alterations of NASH reverting steatosis, preventing the evolution to steatohepatitis, reducing inflammatory macrophage infiltration in the liver and adipose tissue, and starkly mitigating obesity induced by a high-fat diet. Antitumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 68003-38-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 250 mg. Product ID: HY-123986.
CTP inhibitor
CTP inhibitor (Compound 792949) is a potent and selective CTP inhibitor. CTP inhibitor inhibits the plasma membrane citrate transporter (PMCT)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 412940-35-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101998.
CTP - lyophilized
The lyophilized form of CTP. CTP is a P2X purinergic receptor agonist that can be used in the synthesis of RNA. In metabolic reactions, it acts as a coenzyme. Synonyms: Cytidine 5'-triphosphate, Disodium salt trihydrate. Grade: ≥ 95% by HPLC. Molecular formula: C9H14N3Na2O14P3* 3H2O. Mole weight: 581.16.
CTP Synthase (Crude Enzyme)
This product with the indicated enzyme activity was briefly purified from engineered E.coli. Applications: Analysis; drug development; medicine. Group: Enzymes. Synonyms: UTP-ammonia ligase; cytidine triphosphate synthetase; uridine triphosphate aminase; cytidine 5'-triphosphate synthetase; CTPS (gene name); pyrG (gene name); CTP synthase; UTP:ammonia ligase (ADP-forming). Enzyme Commission Number: EC 6.3.4.2. CAS No. 9023-56-7. Activity: Undetermined. Appearance: Clear to translucent yellow solution. Storage: at -20 °C or lower, for at least 1 month. Source: E. coli. UTP-ammonia ligase; cytidine triphosphate synthetase; uridine triphosphate aminase; cytidine 5'-triphosphate synthetase; CTPS (gene name); pyrG (gene name); CTP synthase; UTP:ammonia ligase (ADP-forming). Pack: 100ml. Cat No: NATE-1862.
CTP synthase (glutamine hydrolysing)
The enzyme contains three functionally distinct sites: an allosteric GTP-binding site, a glutaminase site where glutamine hydrolysis occurs (cf. EC 3.5.1.2, glutaminase), and the active site where CTP synthesis takes place. The reaction proceeds via phosphorylation of UTP by ATP to give an activated intermediate 4-phosphoryl UTP and ADP. Ammonia then reacts with this intermediate generating CTP and a phosphate. The enzyme can also use ammonia from the surrounding solution. Group: Enzymes. Synonyms: UTP-ammonia ligase; cytidine triphosphate synthetase; uridine triphosphate aminase; cytidine 5'-triphosphate synthetase; CTPS (gene name); pyrG (gene name); CTP synthase; UTP:ammonia ligase (ADP-forming). Enzyme Commission Number: EC 6.3.4.2. CAS No. 9023-56-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5789; CTP synthase (glutamine hydrolysing); EC 6.3.4.2; 9023-56-7; UTP-ammonia ligase; cytidine triphosphate synthetase; uridine triphosphate aminase; cytidine 5'-triphosphate synthetase; CTPS (gene name); pyrG (gene name); CTP synthase; UTP:ammonia ligase (ADP-forming). Cat No: EXWM-5789.
CTP Synthetase-IN-1
CTP Synthetase-IN-1 is a potent, orally active cytidine 5'-triphosphate synthetase (CTPS) inhibitor with IC50s of 32 nM and 18 nM for human CTPS1 and human CTPS2, respectively. CTP Synthetase-IN-1 has anti-inflammatory effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2338811-71-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152149.
CTR/AMYR modulator-1
CTR/AMYR modulator-1 is a calcitonin receptor/amylin receptor modulator. CTR/AMYR modulator-1 can be used for the research of metabolic disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3097482-67-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-179738.
CTS-1027
CTS-1027 is a potent small molecule inhibitor of MMPs, with IC50s of 0.3 nM, 0.5 nM for MMP2, MMP13, respectively, and has > 1,000 fold selectivity over MMP1. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro 1130830; RS 130830. CAS No. 193022-04-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10398.
CTS-1027
CTS-1027 inhibits individual members of the MMP family that are believed to be important in inflammation and tissue damage. CTS-1027 was specifically designed, however, not to inhibit MMP 1, as inhibition of MMP 1 was believed to be associated with musculoskeletal side effects. Synonyms: RS 130830; Ro 1130830; CTS1027; CTS 1027; RS130830; Ro1130830; RS-130830; Ro-1130830. Grade: >98%. CAS No. 193022-04-7. Molecular formula: C19H20ClNO6S. Mole weight: 425.88.
CTS-21166
CTS-21166, the selective BACE1 inhibitor whose structure is not revealed, reduce brain Aβ levels by over 35% and plaque load by 40%. Phase 1 IC50=1.2-3.6 nM (cell line details NA) APP transgenic mice, 4mg/kg i.p. injection for 6 weeks, >35% ↓ brain Aβ, 40% ↓ plaque load. Human patients, 7.5.225 mg i.v. injection dose-dependant ↓ plasma Aβ, 80% ↓ at 225 mg. Synonyms: ATG-Z1; CTS-21166; ZPQ-21166; ATG Z1; CTS 21166; ZPQ 21166; ATGZ1; CTS21166; ZPQ21166. Molecular formula: none.
CT Series Talc
CT Industrial Talcs can be used in a wide range of industrial and specialty applications. CT Industrial Talcs are produced from an extensive depositof high quality platy talc ore. CT series talcs are a cost effective formulating tool for moderate brightness applications. Pack Sizes Available: 50 lbs bags, 2,000 lbs pallets.
AG&P Mineral Purveyors
CTTHWGFTLC, CYCLIC acetate
CTTHWGFTLC, CYCLIC acetate is a cyclic peptide inhibitor for matrix metalloproteinases (MMP-2) and MMP-9. Synonyms: L-Cysteine, L-cysteinyl-L-threonyl-L-threonyl-L-histidyl-L-tryptophylglycyl-L-phenylalanyl-L-threonyl-L-leucyl-, cyclic (1→10)-disulfide acetate; CTT 1 acetate; H-Cys-Thr-Thr-His-Trp-Gly-Phe-Thr-Leu-Cys-OH.CH3CO2H (Disulfide Bridge: Cys1-Cys10); L-cysteinyl-L-threonyl-L-threonyl-L-histidyl-L-tryptophyl-glycyl-L-phenylalanyl-L-threonyl-L-leucyl-L-cysteine (1->10)-disulfide acetic acid acetate. Grade: ≥95%. Molecular formula: C54H75N13O16S2. Mole weight: 1226.39.
CTX-0294885
CTX-0294885 is a novel broad-spectrum kinase inhibitor. CTx-0294885 exhibits inhibitory activity against a broad range of kinases in vitro. Use of a quantitative proteomics approach confirmed the selectivity of CTx-0294885-bound beads for kinase enrichment. Large-scale CTx-0294885-based affinity purification followed by LC-MS/MS led to the identification of 235 protein kinases from MDA-MB-231 cells, including all members of the AKT family that had not been previously detected by other broad-spectrum kinase inhibitors. CTx-0294885 represents a powerful new reagent for analysis of kinome signaling networks that may facilitate development of targeted therapeutic strategies. Synonyms: CTX 0294885; CTX0294885; Benzamide, 2-[[5-chloro-2-[[4-(1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]-N-methyl-. Grade: 98%. CAS No. 1439934-41-4. Molecular formula: C22H24ClN7O. Mole weight: 437.93.
CTX-0294885
CTX-0294885 is a broad spectrum kinase inhibitor that can capture 235 kinases from MDA-MB-231 cells, and can capture all members of the AKT family. CTX-0294885 is a powerful reagent for analysis of kinome signaling networks that can be used for the research of diseases like inflammation, diabetes, and cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1439934-41-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15985.
CTX-0294885 hydrochloride
CTX-0294885 hydrochloride is the hydrochloride salt of CTX-0294885 which displays high affinity toward an extensive range of kinases. The evaluation of the binding profile of CTx-0294885 in MDA-MB-231 cells by quantitative MS demonstrated its selective properties as a kinase enrichment reagent. Synonyms: 2-[[5-chloro-2-(4-piperazin-1-ylanilino)pyrimidin-4-yl]amino]-N-methylbenzamide; hydrochloride; CTX-0294885 hydrochloride; CTX 0294885 hydrochloride; CTX0294885 hydrochloride. Molecular formula: C22H25Cl2N7O. Mole weight: 474.39.
C-Type Natriuretic Peptide (1-53), human
C-Type Natriuretic Peptide (1-53), human is the 1-53 fragment of C-Type Natriuretic Peptide, which belong to the natriuretic peptide family and is involved in the maintenance of electrolyte-fluid balance and vascular tone. Synonyms: CNP-53 (human); Asp-Leu-Arg-Val-Asp-Thr-Lys-Ser-Arg-Ala-Ala-Trp-Ala-Arg-Leu-Leu-Gln-Glu-His-Pro-Asn-Ala-Arg-Lys-Tyr-Lys-Gly-Ala-Asn-Lys-Lys-Gly-Leu-Ser-Lys-Gly-Cys-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys (Disulfide bond). Grade: ≥95%. CAS No. 141294-77-1. Molecular formula: C251H417N81O71S3. Mole weight: 5801.77.
C-Type Natriuretic Peptide-22 (human, porcine, rat) trifluoroacetate salt
C-Type natriuretic peptide-22 is an endogenous peptide which has diverse biological activities. CNP-22 acts as a selective agonist of natriuretic peptide receptors (NPRs) 2 and 3 (Kds = 7, 10.8, and >500,000 pM for NPR2, 3, and 1, respectively). The 22 amino acid sequence corresponds to residues 105-126 of its precursors prepro CNP, pro CNP, and CNP-53. Synonyms: CNP-22; glycyl-L-leucyl-L-seryl-L-lysylglycyl-L-cysteinyl-L-phenylalanylglycyl-L-leucyl-L-lysyl-L-leucyl-L-α-aspartyl-L-arginyl-L-isoleucylglycyl-L-seryl-L-methionyl-L-serylglycyl-L-leucylglycyl-L-cysteine cyclic (6→22)-disulfide trifluoroacetate salt. Grade: ≥95%. Molecular formula: C93H157N27O28S3·xCF3COOH. Mole weight: 2197.60.
C-Type Natriuretic Peptide (CNP) (1-22), human
C-Type Natriuretic Peptide (CNP) (1-22), human, a 1-22 fragment of CNP, is a natriuretic peptide receptor B (NPR-B) agonist. C-Type Natriuretic Peptide (CNP) (1-22), human inhibits cAMP synthesis stimulated by the physiological agonists histamine and 5-HT or directly by Forskolin. CNP is a potent, endothelial-derived relaxant and growthinhibitory factor[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 127869-51-6. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P1237.
C-Type Natriuretic Peptide (CNP) (1-22), human
C-type natriuretic peptide is an endogenous peptide found in plasma and cerebrospinal fluid. It is composed of 22 amino acids. C-type natriuretic peptide acts as an agonist of natriuretic peptide receptor NPR2 (NPRB) and exhibits affinity for NPR3 (NPRC). It inhibits L-type calcium currents in myocytes and exhibits antiproliferative effects in cardiac fibroblasts in vitro. Regulates cartilage homeostasis, body fluid volume and exhibits vasodilatory activity in vivo. Synonyms: H-Gly-Leu-Ser-Lys-Gly-Cys(1)-Phe-Gly-Leu-Lys-Leu-Asp-Arg-Ile-Gly-Ser-Met-Ser-Gly-Leu-Gly-Cys(1)-OH; glycyl-L-leucyl-L-seryl-L-lysyl-glycyl-L-cysteinyl-L-phenylalanyl-glycyl-L-leucyl-L-lysyl-L-leucyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-glycyl-L-seryl-L-methionyl-L-seryl-glycyl-L-leucyl-glycyl-L-cysteine (6->22)-disulfide; Natriuretic peptide, C-type; C-type natriuretic peptide (1-22) (human, rat, swine); Atriopeptin C (pig); C-Type Natriuretic Peptide (32-53) (human, porcine, rat). Grade: ≥95%. CAS No. 127869-51-6. Molecular formula: C93H157N27O28S3. Mole weight: 2197.60.
C-Type Natriuretic Peptide (CNP) (1-22), human TFA
C-Type Natriuretic Peptide (CNP) (1-22), human (TFA),a 1-22 fragment of CNP, is a natriuretic peptide receptor B (NPR-B) agonist. C-Type Natriuretic Peptide (CNP) (1-22), human (TFA) inhibits cAMP synthesis stimulated by the physiological agonists histamine and 5-HT or directly by Forskolin. CNP is a potent, endothelial-derived relaxant and growthinhibitory factor[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1966153-17-2. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P1237A.
Cu
Cu. Purity: 99.8% (metal basis).
Cu
Cu. CAS No. 20427-59-2. Mole weight: 97.56068 g/mol. Purity: 99.5%.
CU-115
CU-115 is a selective TLR8 inhibitor with IC50 of 1.04 μM. CU-115 was demonstrated that inhibits ssRNA-sensing pathways at low concentrations and does not inhibit other non-endosomal TLR and cytosolic NA-sensing pathways (<5 μ M). Synonyms: N-(4-(3,5-Bis(trifluoromethyl)phenoxy)phenyl)-2-fluoro-6-iodobenzamide. Grade: 98%. CAS No. 2471982-20-2. Molecular formula: C21H11F7INO2. Mole weight: 569.21.
Cu2+-exporting ATPase
A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. The enzyme from the termophilic bacterium Archaeoglobus fulgidus is involved in copper extrusion from the cell. Group: Enzymes. Synonyms: CopB. Enzyme Commission Number: EC 3.6.3.4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4678; Cu2+-exporting ATPase; EC 3.6.3.4; CopB. Cat No: EXWM-4678.
CU-32
CU-32 is an inhibitor of cyclic GMP-AMP (cGAMP) synthase (IC50 = 0.45 μM). Synonyms: methyl 4-amino-6-((4-iodophenyl)amino)-1,3,5-triazine-2-carboxylate. Grade: 95%. CAS No. 2400954-16-5. Molecular formula: C11H10IN5O2. Mole weight: 371.13.
CU-76
An inhibitor of cyclic GMP-AMP synthase (IC50 = 0.24 μM). Synonyms: Methyl 4-amino-6-((3,5-difluoro-4-iodophenyl)amino)-1,3,5-triazine-2-carboxylate. Grade: 95%. CAS No. 2400954-58-5. Molecular formula: C11H8F2IN5O2. Mole weight: 407.11.
CuAlMnTi High-Entropy Alloy Ingots
We are engaged in the development, production, and sales of CuAlMnTi High-Entropy Alloy Ingots and provide personalized customization service for high-quality metal powder. CuAlMnTi High-Entropy Alloy is a new alloy with very unique properties. Purity: 0.99.
CuAlMnTi High-Entropy Alloy Spherical Powder
We are engaged in the development, production and sales of CuAlMnTi high entropy alloy spherical powder, and provide personalized service of high quality metal powder. CuAlMnTi high entropy alloy spherical powder is a new type of alloy with very unique properties.
CuAlTiWV High-Entropy Alloy Spherical Powder
CuAlTiWV High-Entropy Alloy Spherical Powder is composed of Cu, Al, Ti, W, V. Alfa Chemistry offers high-quality High-Entropy Alloy with competitive pricing.
CuATSM
CuATSM is a copper complex that scavenges free radicals, inhibits lipid peroxidation and ferroptosis. CuATSM exhibits antioxidant, anti-inflammatory and neuroprotective activities[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 68341-09-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139827.
CuATSM
CuATSM is a highly potent radical-trapping antioxidant (RTA) and (phosphorus)lipid peroxidation inhibitor, thereby accounting for its ability to inhibit ferroptosis. It is preclinically used as a potential therapy for ALS (amyotrophic lateral sclerosis) and a potential anti-Alzheimer's agent. Synonyms: Cu(II)astm; Copper(II) diacetyl-di(N4-methyl)thiosemicarbazone; [[2,2'-(1,2-Dimethyl-1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato]]]copper; [[2,2'-(1,2-Dimethyl-1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato]](2-)-N2,N2',S,S']-, (SP-4-2)Copper; [[2,2-Prime-(1,2-Dimethyl-1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato]]]copper; (SP-4-2)-[[2,2'-(1,2-dimethyl-1,2-ethanediylidene)bis[N-methylhydrazinecarbothioamidato-κN2,κS]](2-)]-copper; copper-ATSM. Grade: ≥95%. CAS No. 68341-09-3. Molecular formula: C8H14CuN6S2. Mole weight: 321.91.
Cuban Tobacco Fragrance Oil
Cuban Tobacco Fragrance Oil.
CA, FL & NJ
cubebol synthase
Requires Mg2+. The enzyme gives 28% cubebol, 29% (-)-germacrene D, 10% (+)-Δ-cadinene and traces of several other sesquiterpenoids. See also EC 4.2.3.75 (-)-germacrene D synthase and EC 4.2.3.13 (+)-Δ-cadinene synthase. Group: Enzymes. Synonyms: Cop4. Enzyme Commission Number: EC 4.2.3.91. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5255; cubebol synthase; EC 4.2.3.91; Cop4. Cat No: EXWM-5255.
Cubeb Pepper Oil
Cubeb essential oilsis a warm, sweet oil with a slight peppery characteristic. Although Cubeb (Piper cubeba) has similarities to Black Pepper (Piper nigrum), Cubeb essential oilsis not as peppery in aroma as Black Pepper Essential Oil. It's a softer, mellower, warming essential oilsthat serves as a middle-base note in fragrancing applications. Cubeb oil is derived from the fruits of the cubebs plants. Cubeb plants are native to Java and Sumatra Islands but are also grown in India, Sri Lanka, and Reunion, too. Uses: Essential Oils, Pharmaceutical. Group: Plant Extracts. INCI Names: Piper Cubeba (Cubeb Pepper) Fruit Oil. Grades: FOOD GRADE. CAS No. 90082-59-0. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: CB-002. Olfactive Profile: Spicy, pepper-like, piperine, mint-like. EC No: 290-148-4. FEMA No: 2339. Origin: Indonesia.
New Jersey
Cubeb Pepper Oil - CO2
Cubeb essential oilsis a warm, sweet oil with a slight peppery characteristic. Although Cubeb (Piper cubeba) has similarities to Black Pepper (Piper nigrum), Cubeb essential oilsis not as peppery in aroma as Black Pepper Essential Oil. It's a softer, mellower, warming essential oilsthat serves as a middle-base note in fragrancing applications. Cubeb oil is derived from the fruits of the cubebs plants. Cubeb plants are native to Java and Sumatra Islands but are also grown in India, Sri Lanka, and Reunion, too. Uses: Pharmaceutical. Group: Plant Extracts. INCI Names: Piper Cubeba (Cubeb Pepper) Fruit Oil. Grades: FOOD GRADE. CAS No. 90082-59-0 ; 8007-87-2. Pack Sizes: 25 kgs Jerrycan, 200 kg Drums. Product ID: CB-001. Olfactive Profile: Spicy, pepper-like, piperine, mint-like. EC No: 290-148-4. FEMA No: 2339. Origin: Indonesia.
New Jersey
Cubenol
Cubenol was used for biological study of antioxidant and antimicrobial activity and comparison of cinnamon leaf and bark essential oils and oleoresins. Cubenol was one of the major components of essential oils isolated from the aerial parts of Artemisia absinthium, Artemisia santonicum and Artemisia spicigera. Group: Biochemicals. Grades: Highly Purified. CAS No. 21284-22-0. Pack Sizes: 10mg, 50mg. Molecular Formula: C15H26O, Molecular Weight: 222.37. US Biological Life Sciences.
Worldwide
CU-CPD107
CU-CPD107 is a a tetrasubstituted imidazole that inhibits R848-induced TLR8 signaling. In the presence of R848, CU-CPD107 acts as a TLR8 signaling inhibitor with IC50 of 13.7 μM. Synonyms: GD0. CAS No. 2573912-32-8. Molecular formula: C16H21IN2O2. Mole weight: 400.26.
CU-CPD107
CU-CPD107 is a potent, selective toll-like receptor 8 (TLR 8) agonist. CU-CPD107 inhibits TLR8 signaling. CU-CPD107 converts to synergistic agonist activities in the presence of ssRNA and induces TLR8 signaling. CU-CPD107 inhibits proinflammatory factor expression and avoids immune responses in the presence of ssRNA[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2573912-32-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-147310.
CU-CPT17e
CU-CPT17e is a potent multi-Toll-like receptor (TLR) agonist that activates TLR3, TLR8, and TLR9. Uses: Scientific research. Category: Signaling pathways. CAS No. 2109805-75-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101929.
CU CPT 22
CU CPT 22 is a selective TLR1/2 inhibitor (IC50 = 0.58 μM). Synonyms: CU-CPT22; CU-CPT 22; CU-CPT-22; CUCPT22; CUCPT 22; CUCPT-22; 3,4,6-Trihydroxy-2-methoxy-5-oxo-5H-benzocycloheptene-8-carboxylic acid hexyl ester. CAS No. 1416324-85-0. Molecular formula: C19H22O7. Mole weight: 362.37.
CU-CPT22
CU-CPT22 is a potent protein complex of toll-like receptor 1 and 2 (TLR1/2) inhibitor, and competes with the synthetic triacylated lipoprotein (Pam3CSK4) binding to TLR1/2 with a Ki of 0.41 μM. CU-CPT22 blocks Pam3CSK4-induced TLR1/2 activation with an IC50 of 0.58 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1416324-85-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108471.
CU CPT 4a
CU CPT 4a is a selective TLR3 inhibitor (IC50 = 3.44 μM in RAW 264.7 cells). Synonyms: CU CPT 4a; CU-CPT-4a; CUCPT4a; N-[(3-Chloro-6-fluorobenzo[b]thien-2-yl)carbonyl]-D-phenylalanine. CAS No. 1279713-77-7. Molecular formula: C18H13ClFNO3S. Mole weight: 377.82.
CU-CPT 4a
CU-CPT 4a (TLR3-IN-1) is a potent, highly selective TLR3 signaling inhibitor. CU-CPT 4a represses the expression of downstream signaling pathways mediated by the TLR3/dsRNA complex, including TNF-α and IL-1β[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TLR3-IN-1. CAS No. 1279713-77-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108473.
CU-CPT-8m
CU-CPT-9m is a TLR8 antagonist with an IC50 of 67 nM. Synonyms: CU-CPT-8m, CU-CPT 8m, CU-CPT8m; 7-(m-tolyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide; 7-(3-methylphenyl) pyrazolo(1,5-a)pyrimidine-3-carboxamide; 7-(3-methylphenyl) pyrazolo[1,5-a]pyrimidine-3-carboxamide; CU-CPT8m. CAS No. 125079-83-6. Molecular formula: C14H12N4O. Mole weight: 252.277.
CU-CPT-8m
CU-CPT-8m is a specific TLR8 antagonist, with an IC50 of 67 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TLR8-specific antagonist. CAS No. 125079-83-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112050.
CU-CPT-9a
CU-CPT-9a is a specific TLR8 antagonist, with an IC50 of 0.5 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 2165340-32-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112667.
CU-CPT-9a
CU-CPT-9a is a TLR8 antagonist with an IC50 of 0.5 nM. Synonyms: CU-CPT9b; CUCPT9b; CU CPT9b; HY-112667; CS-0059157; HY 112667; CS 0059157; HY112667; CS0059157; 4-(3-methyl-4-oxidanyl-phenyl)quinolin-7-ol; 2-Methyl-4-(7-hydroxyl-4-quinolinyl)-phenol. CAS No. 2162962-69-6. Molecular formula: C16H13NO2. Mole weight: 251.285.
CU-CPT-9b
CU-CPT-9b is a TLR8 inhibitor that inhibits TLR8-mediated proinflammatory signaling in various cell lines and human primary cells. Synonyms: CU-CPT9a; 2-Methyl-4-(7-methoxy-4-quinolinyl)phenol; CU CPT 9a; BCP29122; BCP-29122; CUCPT9a; BCP 29122; 4-(7-methoxy-1H-quinolin-4-ylidene)-2-methylcyclohexa-2,5-dien-1-one; Phenol, 4-(7-methoxy-4-quinolinyl)-2-methyl-; 4-(7-Methoxy-4-quinolinyl)-2-methylphenol. Grade: ≥95%. CAS No. 2165340-32-7. Molecular formula: C17H15NO2. Mole weight: 265.31.
CuCrZr High-Entropy Alloy Ingots
We are engaged in the development, production, and sales of CuCrZr High-Entropy Alloy Ingots and provide personalized customization service for high-quality metal powder. CuCrZr High-Entropy Alloy is a new alloy with very unique properties. Purity: 0.99.
CuCrZr High-Entropy Alloy Spherical Powder
We are engaged in the development, production and sales of CuCrZr high entropy alloy spherical powder, and provide personalized service for high quality metal powder. CuCrZr high entropy alloy spherical powder is a new type of alloy with very unique properties.
Cucumber Powder
Cucumber powder is made from Cucumis sativus, a widely cultivated plant in the gourd family Cucurbitaceae. Cucumber powder is a great ingredient to help revitalize the skin. Cucumber powder has many benefits for skin, it helps relieve the puffiness of the skin. Cucumber powder also helps remove dead skin cells and tightens skin. Group: Others. Cucumber Powder; Cucumis Sativus Linn. Cat No: EXTC-106.
cucumisin
From the sarcocarp of the musk melon (Cucumis melo). In peptidase family S8 (subtilisin family). Other endopeptidases from plants, which are less well characterized but presumably of serine-type, include euphorbain from Euphorbia cerifera, solanain from horse-nettle Solanum elaeagnifolium, hurain from Hura crepitans and tabernamontanain from Tabernamontana grandiflora. Group: Enzymes. Synonyms: euphorbain; solanain; hurain; tabernamontanain. Enzyme Commission Number: EC 3.4.21.25. CAS No. 82062-89-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4123; cucumisin; EC 3.4.21.25; 82062-89-3; euphorbain; solanain; hurain; tabernamontanain. Cat No: EXWM-4123.
Cucurbit[5]uril hydrate
Cucurbiturils are macrocyclic molecules made of glycoluril monomers linked by methylene bridges. The oxygen atoms are located along the edges of the band and are tilted inwards, forming a partly enclosed cavity. Cucurbiturils are commonly written as cucurbit[n]uril, where n is the number of glycoluril units. Two common abbreviations are CB[n], or simply CBn. Molecular formula: C30H30N20O10 · xH2O · xKCl · xHCl. SMILES: O.Cl.[Cl-].[K+].O=C1N2CN3C4C5N(CN6C7C8N(CN9C%10C%11N(CN%12C%13C%14N(CN1C%15C2N%16CN4C(=O)N5CN7C(=O)N8CN%10C(=O)N%11CN%13C(=O)N%14CN%15C%16=O)C%12=O)C9=O)C6=O)C3=O. InChI: 1S/C30H30N20O10.2ClH.K.H2O/c51-21-31-1-32-12-14-36(22(32)52)4-40-16-18-44(26(40)56)8-48-20-19-47(29(48)59)7-43-17-15-39(25(43)55)3-35(21)13-11(31)33-2-34(12)24(54)38(14)6-42(16)28(58)46(18)10-50(20)30(60)49(19)9-45(17)27(57)41(15)5-37(13)23(33)53;;;;/h11-20H,1-10H2;2*1H;;1H2/q;;;+1;/p-1/t11-,12+,13+,14-,15-,16+,17+,18-,19-,20+;;;
Cucurbit[7]uril is a cyclic organic molecule consisting of seven glycoluril units linked by methylene bridges. It has a rigid barrel-like structure with two identical inlets at both ends to selectively encapsulate guest molecules of appropriate size, shape, and polarity. Cucurbit[7]uril is known for its high binding affinity for a variety of organic and inorganic guests, including drugs, amino acids, peptides, and metal ions. This property makes them promising candidates for various applications in areas such as drug delivery, catalysis, and sensing. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CB7; Carrier CB7. CAS No. 259886-50-5. Pack Sizes: 10 mM * 1 mL in Water; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-104086.
Cucurbit[7]uril hydrate
Cucurbiturils are macrocyclic molecules made of glycoluril monomers linked by methylene bridges. The oxygen atoms are located along the edges of the band and are tilted inwards, forming a partly enclosed cavity. Cucurbiturils are commonly written as cucurbit[n]uril, where n is the number of glycoluril units. Two common abbreviations are CB[n], or simply CBn. Molecular formula: C42H42N28O14 · xH2O · xHCl. Mole weight: 1181g/mol. IUPAC Name: 3,5,8,10,13,15,18,20,23,25,28,30,33,35,36,38,40,42,46,48,50,52,54,56,58,60,62,64-octacosazadocosacyclo[30.3.3.36,7.311,12.316,17.321,22.326,27.22,36.231,38.13,35.15,8.110,13.115,18.120,23.125,28.130,33.140,46.142,64.148,50.152,54.156,58.160,62]heptacontane-39,41,43,44,45,47,49,51,53,55,57,59,61,63-tetradecone;hydrate. SMILES: O.Cl.O=C1N2CN3C4C5N(CN6C7C8N(CN9C%10C%11N(CN%12C%13C%14N(CN%15C%16C%17N(CN%18C%19C%20N(CN1C%21C2N%22CN4C(=O)N5CN7C(=O)N8CN%10C(=O)N%11CN%13C(=O)N%14CN%16C(=O)N%17CN%19C(=O)N%20CN%21C%22=O)C%18=O)C%15=O)C%12=O)C9=O)C6=O)C3=O. InChI: 1S/C42H42N28O14.ClH.H2O/c71-29-43-1-44-16-18-48(30(44)72)4-52-20-22-56(34(52)76)8-60-24-26-64(38(60)80)12-68-28-27-67(41(68)83)11-63-25-23-59(37(63)79)7-55-21-19-51(33(55)75)3-47(29)17-15(43)45-2-46(16)32(74)50(18)6-54(20)36(78)58(22)10-62(24)40(82)66(26)14-70(28)42(84)69(27)13-65(25)39(81)61(23)9-57(21)35(77)53(19)5-49(17)31(45)73;;/h15-28H,1-14H2;1H;1H2/t15-,16+,17+,18-,19-,20+,21+,22-,23-,24+,25+,26-,27-,28+;
Cucurbit(8)uril. Alternative Names: Cucurbit[8]uril;Curcubit[8]uril;Cucurbit[8]uril (CB[8]) hydrate, 99+%;Cucurbit[8]uril hydrate contains acid of crystalization;Cucurbit[8]uril hydrate;2,20:3,19-Dimethano-2,3,4a,5a,6a,7a,8a,9a,10a,11a,12a,13a,14a,15a,16a,17a,19,20,21a,22a,23a,24a,25a,26a,27a,28a,29a,30a,31a,32a,33a,34a-dotriacontaazabispentaleno[1,6:5,6,7]cycloocta[1,2,3:3,4]pentaleno[1,6:5. CAS No. 259886-51-6. Molecular formula: C48H48N32O16. Mole weight: 1329.1g/mol. IUPAC Name: 3,5,8,10,13,15,18,20,23,25,28,30,33,35,38,40,41,43,45,47,51,53,55,57,59,61,63,65,67,69,71,73-dotriacontazapentacosacyclo[35.3.3.36,7.311,12.316,17.321,22.326,27.331,32.22,41.236,43.13,40.15,8.110,13.115,18.120,23.125,28.130,33.135,38.145,51.147,73.153,55.157,59.161,63.165,67.169,71]octacontane-44,46,48,49,50,52,54,56,58,60,62,64,66,68,70,72-hexadecone. SMILES: C1N2C3C4N(C2=O)CN5C6C7N(C5=O)CN8C9C2N(C8=O)CN5C8C%10N(C5=O)CN5C%11C%12N(C5=O)CN5C%13C%14N(C5=O)CN5C%15C%16N(C5=O)CN5C%17C(N1C5=O)N1CN3C(=O)N4CN6C(=O)N7CN9C(=O)N2CN8C(=O)N%10CN%11C(=O)N%12CN%13C(=O)N%14CN%15C(=O)N%16CN%17C1=O. InChI: InChI=1S/C48H48N32O16/c81-33-49-1-50-18-20-54(34(50)82)4-58-22-24-62(38(58)86)8-66-26-28-70(42(66)90)12-74-30-32-78(46(74)94)15-77-31-29-73(45(77)93)11-69-27-25-65(41(69)89)7-61-23-21-57(37(61)85)3-53(33)19-17(49)51-2-52(18)36(84)56(20)6-60(22)40(88)64(24)10-68(26)44(92)72(28)14-76(30)48(96)80(32)16-79(31)47(95)75(29)13-71(27)43(91)67(25)9-63(23)39(87)59(21)5
Cucurbit[8]uril hydrate
Cucurbiturils are macrocyclic molecules made of glycoluril monomers linked by methylene bridges. The oxygen atoms are located along the edges of the band and are tilted inwards, forming a partly enclosed cavity. Cucurbiturils are commonly written as cucurbit[n]uril, where n is the number of glycoluril units. Two common abbreviations are CB[n], or simply CBn. Molecular formula: C48H48N32O16 · xH2O · xHCl. Mole weight: 1347.1g/mol. IUPAC Name: 3,5,8,10,13,15,18,20,23,25,28,30,33,35,38,40,41,43,45,47,51,53,55,57,59,61,63,65,67,69,71,73-dotriacontazapentacosacyclo[35.3.3.36,7.311,12.316,17.321,22.326,27.331,32.22,41.236,43.13,40.15,8.110,13.115,18.120,23.125,28.130,33.135,38.145,51.147,73.153,55.157,59.161,63.165,67.169,71]octacontane-44,46,48,49,50,52,54,56,58,60,62,64,66,68,70,72-hexadecone;hydrate. SMILES: O.Cl.O=C1N2CN3C4C5N(CN6C7C8N(CN9C%10C%11N(CN%12C%13C%14N(CN%15C%16C%17N(CN%18C%19C%20N(CN%21C%22C%23N(CN1C%24C2N%25CN4C(=O)N5CN7C(=O)N8CN%10C(=O)N%11CN%13C(=O)N%14CN%16C(=O)N%17CN%19C(=O)N%20CN%22C(=O)N%23CN%24C%25=O)C%21=O)C%18=O)C%15=O)C%12=O)C9=O)C6=O)C3=O. InChI: 1S/C48H48N32O16.ClH.H2O/c81-33-49-1-50-18-20-54(34(50)82)4-58-22-24-62(38(58)86)8-66-26-28-70(42(66)90)12-74-30-32-78(46(74)94)15-77-31-29-73(45(77)93)11-69-27-25-65(41(69)89)7-61-23-21-57(37(61)85)3-53(33)19-17(49)51-2-52(18)36(84)56(20)6-60(22)40(88)64(24)10-68(26)44(92)72(28)14-76(30)48(96)80(32)16-79(31)47(95)75(29)13-71(27)43(91)67(25)9-63(23)39
Cucurbitacin A
Cucurbitacin A. Group: Biochemicals. CAS No. 6040-19-3. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Cucurbitacin A
Cucurbitacin A is a triterpenoid sterol isolated from rhizomes of Hemsleya amabilis Diels. Synonyms: Cucurbitacin A; 6040-19-3; UNII-83859; MTO77NSC94743; CHEBI:3940. Grade: >98%. CAS No. 6040-19-3. Molecular formula: C32H46O9. Mole weight: 574.711.
Cucurbitacin B
Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6199-67-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0416.
Cucurbitacin B
Cucurbitacin B. Group: Biochemicals. Alternative Names: Amarin. Grades: Plant Grade. CAS No. 6199-67-3. Pack Sizes: 20mg. Molecular Formula: C32H46O8, Molecular Weight: 558.703. US Biological Life Sciences.
Worldwide
Cucurbitacin B (Standard)
Cucurbitacin B (Standard) is the analytical standard of Cucurbitacin B. This product is intended for research and analytical applications. Cucurbitacin B belongs to a class of highly oxidized tetracyclic triterpenoids and is oral active. Cucurbitacin B inhibits tumor cell growth, migration and invasion and cycle arrest, but induces cell apoptosis. Cucurbitacin B has potent anti-inflammatory, antioxidant, antiviral, hypoglycemic, hepatoprotective, neuroprotective activity[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6199-67-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0416R.
Cucurbitacin C
Cucurbitacin C is a triterpenoid calabinoid that can be isolated from Cucurbitaceae plants. Cucurbitacin C has anti-cancer activity in vivo and in vitro. Cucurbitacin C can induce cell cycle arrest in G1 or G2/M phase and apoptosis by inhibiting Akt signaling[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5988-76-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N9968.
Cucurbitacin D
Cucurbitacin D. Group: Biochemicals. CAS No. 3877-86-9. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Cucurbitacin D
Cucurbitacin D is the active ingredient in Trichosanthes kirilowii and can disrupt the interaction between Hsp90 and two co-chaperones, Cdc37 and p23. Cucurbitacin D is an inflammasome activator. Cucurbitacin D induces cell cycle arrest and cell apoptosis, exhibiting anti-tumor and anti-inflammatory effects[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3877-86-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N1986.
cucurbitacin Δ23-reductase
Requires Mn2+. Fe2+ or Zn2+ can replace Mn2+ to some extent. Group: Enzymes. Synonyms: NAD(P)H: cucurbitacin B Δ23-oxidoreductase. Enzyme Commission Number: EC 1.3.1.5. CAS No. 37256-38-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1322; cucurbitacin Δ23-reductase; EC 1.3.1.5; 37256-38-5; NAD(P)H: cucurbitacin B Δ23-oxidoreductase. Cat No: EXWM-1322.