A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Seaweed Extract with N.P.K 5.5.5. Uses: Agriculture, horticulture, amenity. Alternative Names: NPK Fertilizers. Grades: High. Pack Sizes: 1000 Litres. Molecular formula: Used as a fertilizer and foliar spray for protection of crops & grass against heat stress. Mole weight: Used through spray nozzles and drip irrigation. Sold wholesale for blending & formulating. Categories: Seaweed extracts (SEs).
CS-6253
CS-6253 is an agonist of ABCA1. CS-6253 can regulate lipoprotein metabolism, promote high-density lipoprotein biogenesis, and cellular cholesterol efflux. CS-6253 also has certain neuroprotective effects and can clear Aβ from the brain. CS-6253 can be used for research on cholesterol metabolism and diseases such as Alzheimers disease[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1627911-44-7. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P6306.
CS640
CS640 (Compound 19) is a chemical probe and a calmodulin-dependent kinase inhibitor. CS640 inhibits CaMK1D, CaMK1B, CaMK1A, CaMK1G, MEK5, RIPK4, mLK3 and PIP5K1, with IC50 values of 8, 3, 1, 1, 25 nM, 5.69, 2.75 and 11.2 μM, respectively. CS640 blocks Aβ-induced hyperphosphorylation of tau protein at the Thr181 site, but fails to protect primary mouse cortical neurons from Aβ-induced toxic damage. CS640 is applicable to research related to Alzheimer's disease[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2388506-83-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148907.
CS-7017 monohydrate
CS-7017 monohydrate is a peroxisome proliferator activated receptor gamma (PPAR) agonist. It is a potential therapy for thyroid cancer and liposarcoma. It is also used for the treatment of rectal cancer and non-small cell lung cancer. It was developed by Daiichi Sankyo Company Limited. It is in clinic phase 2 with no progress. Uses: Cs-7017 monohydrate is a potential therapy for thyroid cancer and liposarcoma. it is also used for the treatment of rectal cancer and non-small cell lung cancer. Synonyms: CS-7017 monohydrate; CS 7017 monohydrate; CS7017 monohydrate; Efatutazone dihydrochloride monohydrate; 5-[[4-[[6-(4-Amino-3,5-dimethylphenoxy)-1-methylbenzimidazol-2-yl]methoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione hydrate dihydrochloride; Inolitazone dihydrochloride monohydrate; (+/-)-2,4-Thiazolidinedione, 5-((4-((6-(4-amino-3,5-dimethylphenoxy)-1-methyl-1H-benzimidazol-2-yl)methoxy)phenyl)methyl)-, dihydrochloride, monohydrate. Grade: >99 %. CAS No. 1048002-36-3. Molecular formula: C27H30Cl2N4O5S. Mole weight: 593.52.
CS 722
CS 722 is a neuromuscular blocking agent and centrally acting muscle relaxant. It exerts its muscle relaxant action by affecting both the supraspinal structure and the spinal cord. In Oct 2000, Phase II for Hypertonia in Japan was discontinued. Uses: Muscle hypertonia. Synonyms: CS 722; CS-722; CS722. 4-Chloro-2-(2-hydroxy-3-morpholinopropyl)-5-phenyl-4-isoxazolin-3-one. Grade: 98%. CAS No. 144886-17-9. Molecular formula: C16H20Cl2N2O4. Mole weight: 375.25.
CS-834
CS-834, a carbapenem derivative, has been found to be a cell wall inhibitor that was once studied as an antiibacterial agent by Sankyo. Synonyms: CS 834; CS834; CS-834; UNII-H26S03B779; [(2,2-dimethylpropanoyl)oxy]methyl (4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-3-{[(3R)-5-oxopyrrolidin-3-yl]sulfanyl}-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate. Grade: 98%. CAS No. 157542-49-9. Molecular formula: C20H28N2O7S. Mole weight: 440.51.
CSF1R-IN-1
CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM. Synonyms: CSF1R Inhibitor Compound 22; CHEMBL4084391; EX-A5045; HY-101774. Grade: 98%. CAS No. 2095849-04-8. Molecular formula: C25H20F3N5O2. Mole weight: 479.5.
CSF1R-IN-24
CSF1R-IN-24 (Example 134) is an orally active CSF1R inhibitor. CSF1R-IN-24 significantly inhibits the survival of human ipSC-derived microglia (hiPSC-MG)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3024322-57-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160842.
CSK-IN-1 (compound 13) is a potent, orally active c-terminal Src kinase (CSK) with IC50 values below 3 nM and 4 nM in CSK HTRF and Caliper assay, respectively. CSK-IN-1 shows the ability to increase T cell proliferation induced by T cell receptor signaling[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2380027-49-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130254.
CS-M1995
CS-M1995 is a 4'-Azidocytidine analogue. It can inhibit Hepatitis C virus replication. Uses: Cs-m1995 can inhibit hepatitis c virus replication. Synonyms: CS-M1995; CS M1995; CSM1995; Nucleoside-Analog-1; 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one, 2-azido-2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-, (2R,3S,3aS,9aR)-; (2R,3S,3aS,9aR)-2-azido-3-hydroxy-2-(hydroxymethyl)-3a,9a-dihydro-3H-furo[1,2][1,3]oxazolo[3,4-a]pyrimidin-6-one. Grade: >98 %. CAS No. 876707-99-2. Molecular formula: C9H9N5O5. Mole weight: 267.20.
CS-M1996
CS-M1996 is a 4'-Azidocytidine analogue. It can inhibit Hepatitis C virus replication. Uses: Cs-m1996 can inhibit hepatitis c virus replication. Synonyms: CS-M1996; CS M1996; CSM1996; 2,4(1H,3H)-PyriMidinedione, 1-(4-C-azido-β-D-arabinofuranosyl)- (9CI); Nucleoside-Analog-2; 1-[(2R,3S,4S,5R)-5-azido-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione. Grade: >98 %. CAS No. 876708-01-9. Molecular formula: C9H11N5O6. Mole weight: 285.21.
CSN5i-3 is a potent, selective and orally available inhibitor of CSN5/Jab1, and inhibits CSN-catalysed Cul1 deneddylation with an IC50 value of 5.8 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2375740-98-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112134.
CSNK1-IN-1
CSNK1-IN-1 is a CSNK1A1 inhibitor. CSNK1-IN-1 has inhibitory activity for CSNK1A1 kinase with IC50 values of 21 μM. CSNK1-IN-1 can be used for the research of proliferative disorders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2468784-55-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148489.
CSP1
CSP1 is a potent and selective ComD1 receptor agonist, with an IC50 of 10.3 nM. CSP1 is a major variants of competence-stimulating peptide (CSP), and it can regulate genetic transformation of S. pneumonia by modulating quorum sensing (QS). CSP1 can act as an antibacterial agent[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 172889-49-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2454.
CSPD
CSPD is a chemiluminescent alkaline phosphatase substrate used for the imprinting of proteins or nucleic acids on nitrocellulose membranes. Synonyms: 3-(2'-(Spiro-5-chloroadamantane))-4-methoxy-4-(3''-phosphoryloxy)phenyl-1,2-dioxetane; 3-(4-Methoxyspiro(1,2-dioxetane-3,2'-(5'-chloro)tricyclo(3.3.1.1(3,7))decan)-4-yl)phenyl phosphate; Phenol, 3-(5'-chloro-4-methoxyspiro(1,2-dioxetane-3,2'-tricyclo(3.3.1.1(3,7))decan)-4-yl)-, dihydrogen phosphate. Grade: >96% by HPLC. CAS No. 142456-88-0. Molecular formula: C18H22ClO7P. Mole weight: 416.79.
CSPGAKVRC-LNP@mRNA
CD Bioparticles CSPGAKVRC-LNP@mRNA combines a CD206-targeting CSPGAKVRC peptide with lipid nanoparticles for precise mRNA delivery to M2 tumour-associated macrophages. This advanced formulation enables efficient mRNA protection, cellular entry, and protein translation. Group: Targeted liposomes.
CSRM617
CSRM617 is an inhibitor of the transcription factor ONECUT2 (OC2), thereby suppressing metastasis in mice. CSRM617 induces apoptosis by appearance of cleaved Caspase-3 and PARP. Synonyms: (2RS)-2-Amino-3-hydroxy-N'-[(EZ)-(2,3,4-trihydroxyphenyl)methylidene]propanehydrazide; Benserazide hydrochloride EP Impurity C. CAS No. 787504-88-5. Molecular formula: C10H13N3O5. Mole weight: 255.23.
CSRM617 hydrochloride
CSRM617 hydrochloride is a selective small-molecule inhibitor of the transcription factor ONECUT2 (OC2, a master regulator of androgen receptor) with a Kd of 7.43 uM in SPR assays, binding to OC2-HOX domain directly. CSRM617 hydrochloride induces apoptosis by appearance of cleaved Caspase-3 and PARP. CSRM617 hydrochloride is well tolerated in the prostate cancer mouse model[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1353749-74-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122611A.
Css54
Css54 is an antibacterial peptide isolated from Centruroides suffusus. It has activity against Staphylococcus aureus (MIC=12.5 μg/ml) and Escherichia coli (MIC=12.5 μg/ml). Cytotoxicity. Synonyms: Phe-Phe-Gly-Ser-Leu-Leu-Ser-Leu-Gly-Ser-Lys-Leu-Leu-Pro-Ser-Val-Phe-Lys-Leu-Phe-Gln-Arg-Lys-Lys-Glu. Grade: 96.1%. Molecular formula: C138H221N33O33. Mole weight: 2870.47.
CST530
CST530 is an inhibitor of apoptosis protein (IAP) antagonist. CST530 is an IAP-type Ligands for E3 Ligase. CST530 binds to the BIR3 domain of IAP and interferes with its function, thereby promoting the ubiquitination and degradation of cIAP1. CST530 can be used to prepare PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 847137-53-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-150825.
CST626
CST626 (Compound 9) is a pan-IAP degrader PROTAC. CST626 degrades XIAP, cIAP1 and cIAP2 with DC50s of 0.7, 2.4, and 6.2 nM in MM.1S cells, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3033993-13-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-149924.
CST967
CST967 (Compound 17) is a USP7 PROTAC degrader, and increasing the PROTAC concentration can enhance the degradation rate of USP7. CST967 can be used in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3093667-09-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-160502.
CT-1
CT-1 is a novel orally active DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis. Synonyms: 3,5-Bis-(2-fluoro-benzylidene)-1-[1-(4-fluoro-benzyl)-1H-[1,2,3]triazol-4-ylmethyl]-piperidin-4-one. CAS No. 1983924-33-9. Molecular formula: C29H23F3N4O. Mole weight: 500.51.
CT1113
CT1113 is a selective, orally active USP25/USP28 inhibitor. CT1113 inhibits cancer cell proliferation, induces apoptosis, and causes G2/S phase cell cycle arrest. CT1113 reduces the levels of total BCR-ABL1, phosphorylated BCR-ABL1, total STAT5, and phosphorylated STAT5, but does not alter the mRNA level of BCR-ABL1. CT1113 is applicable to research related to pancreatic cancer, colon cancer, and acute leukemia[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2523435-18-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-153996.
CT-179
CT-179 is a brain-penetrant and orally active OLIG2 inhibitor with a human IC50 of 1250 nM. CT-179 disrupts OLIG2 dimerization, phosphorylation, and DNA binding, blocking OLIG2-driven transcription. CT-179 induces G2/M phase arrest and increases G0 population. CT-179 induces apoptosis by reducing anti-apoptotic proteins and increasing cleaved caspase-3 and cleaved PARP. CT-179 can be used for the research of subgroup medulloblastoma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1996636-69-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-179078.
Fast cooling rate and high stability. High-efficiency Peltier precision temperature control with good homogeneity. Multi-colour LEDs to indicate different operating status. Built-in module reminder function. Compact product design, small footprint. Multiple module choices, easy replacement of magnetic adsorption, suitable for a wide range of test tubes, and support for continuous operation. It takes only about 10 minutes to reduce the temperature from room temperature to 4°C. Categories: Labooratory Heating & Cooling Equipment.
CT7001 hydrochloride
CT7001, also known as ICEC0942, is an orally bioavailable CDK7 inhibitor with IC50 value of 40nM. CDK7 phosphorylates the C-terminal domain (CTD) of RNA polymerase II (PolII) to enable transcription initiation, and also affects some transcriptional factor activities, resulting in suppression of types of cancers. Synonyms: ICEC0942 hydrochloride; (3R,4R)-4-[[[7-(benzylamino)-3-propan-2-ylpyrazolo[1,5-a]pyrimidin-5-yl]amino]methyl]piperidin-3-ol hydrochloride. CAS No. 1805789-54-1. Molecular formula: C22H31ClN6O. Mole weight: 430.97.
CT-721
CT-721 is a potent and time-dependent inhibitor of Bcr-Abl kinase with an IC50 of 21.3 nM for wild-type Bcr-Abl kinase, and has anti-chronic myeloid leukemia (CML) activity. Synonyms: (1S)-N-{3-[(6-Chloroimidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methylphenyl}-1-(4-methyl-1-piperazinyl)-5-indanecarboxamide; 1H-Indene-5-carboxamide, N-[3-[2-(6-chloroimidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methylphenyl]-2,3-dihydro-1-(4-methyl-1-piperazinyl)-, (1S)-. Grade: ≥98%. CAS No. 1388710-60-8. Molecular formula: C30H29ClN6O. Mole weight: 525.04.
CT-996
CT-996 is an orally active GLP-1RA agonist with an EC50 of 0.49 nM. CT-996 reduces the recruitment of β-arrestin and the internalization of GLP-1R. CT-996 suppresses postprandial blood glucose in mice expressing human GLP-1 receptors and enhances glucose-stimulated insulin secretion (GSIS) in obese monkeys during intravenous glucose challenge. CT-996 can be used for the research of type 2 diabetes (T2D) and obesity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RO7795081; RG6652. CAS No. 2810808-95-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-175701.
CTA056
CTA056 is a potent and selective ITK inhibitor (interleukin-2-inducible T-cell kinase inhibitor). ITK is a member of the Btk (Bruton's tyrosine kinase) family of tyrosine kinases, plays an important role in normal T-cell functions and in the pathophysiology of both autoimmune diseases and T-cell malignancies. CTA056 exhibits the highest inhibitory effects toward Itk, followed by Btk and endothelial and epithelial tyrosine kinase. Among the 41 cancer cell lines analyzed, CTA056 selectively targets acute lymphoblastic T-cell leukemia and cutaneous T-cell lymphoma. CTA056 may be potential therapeutic agent for the treatment of T-cell leukemia and lymphoma. Synonyms: CTA-056; CTA 056; 1,5-Dihydro-7-(phenylmethyl)-1-[3-(1-piperidinyl)propyl]-2-[4-(4-pyridinyl)phenyl]-6H-imidazo[4,5-g]quinoxalin-6-one. Grade: 98%. CAS No. 1265822-30-7. Molecular formula: C35H34N6O. Mole weight: 554.69.
Ct-AMP1
HGAPDH is a plant defensin isolated from Clitoria ternatea. It has activity against gram-positive bacteria and fungi. Synonyms: Asn-Leu-Cys-Glu-Arg-Ala-Ser-Leu-Thr-Trp-Thr-Gly-Asn-Cys-Gly-Asn-Thr-Gly-His-Cys-Asp-Thr-Gln-Cys-Arg-Asn-Trp-Glu-Ser-Ala-Lys-His-Gly-Ala-Cys-His-Lys-Arg-Gly-Asn-Trp-Lys-Cys-Phe-Cys-Tyr-Phe-Asp-Cys. Molecular formula: C234H344N76O71S8. Mole weight: 5614.25.
CTAP
CTAP is a potent, highly selective, and BBB penetrant μ opioid receptor antagonist, with an IC50 of 3.5 nM. CTAP displays over 1200-fold selectivity over δ opioid (IC50=4500 nM) and somatostatin receptors. CTAP can be used for the study of L-DOPA-induced dyskinesia (LID) and opiate overdose or addiction[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 103429-32-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1335.
CTAP
CTAP has been found to be a selective μ-opioid receptor antagonist. Synonyms: D-Phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-arginyl-L-threonyl-3-mercapto-L-valyl-L-threoninamide cyclic (2→7)-disulfide. Grade: ≥95% by HPLC. CAS No. 103429-32-9. Molecular formula: C51H69N13O11S2. Mole weight: 1104.32.
CTAP
CTAP. Group: Biochemicals. Grades: Purified. CAS No. 103429-32-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CTAP (Mu Opioid Receptor Antagonist, CTAP)
A highly potent octapeptide that acts as a selective and brain penetrating bioavailable u opioid receptor antagonist (IC50 = 3.5nM). Used in studies of reward systems and additions. Group: Biochemicals. Grades: Highly Purified. CAS No. 103429-32-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CTAP TFA
CTAP TFA is a potent brain penetrant μ opioid receptor antagonist (IC50 = 3.5 nM) and displays over 1200-fold selectivity over δ opioid (IC50 = 4500 nM) and somatostatin receptors. Synonyms: Cys2, Tyr3, Arg5, Pen7-Amide TFA. Grade: 99%. Molecular formula: C53H70F3N13O13S2. Mole weight: 1218.32.
CTAP trifluoroacetate salt
CTAP is a water-soluble and selective antagonist of the μ opioid receptor (IC50 = 3.5 nM) over the δ receptor (IC50 = 4,500 nM). It is a cyclic octapeptide which acts as a poor antagonist of the somatostatin receptor (IC50 = 14.3 μM). CTAP is at least 10-fold more potent than naltrexone. Molecular formula: C51H69N13O11S2·xCF3COOH. Mole weight: 1104.31.
CTB
CTB is a p300 histone acetyltransferase activator. Synonyms: CTPB; N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-benzamide. CAS No. 451491-47-7. Molecular formula: C16H13ClF3NO2. Mole weight: 343.73.
CTB
CTB is a potent p300 histone acetyltransferase activator[1]. CTB can effectively induce apoptosis in MCF-7 cells[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 451491-47-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134964.
CTCE-0214
CTCE-0214 is a chemokine CXC receptor 4 (CXCR4) agonist, SDF-1α (stromal cell-derived factor-1α) peptide analog. CTCE-0214 shows anti-inflammatory activity, and can be used in inflammation sepsis and systemic inflammatory syndromes research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 577782-52-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3612.
CTCE 9908
It is a CXCR4 antagonist that induces mitotic catastrophe in ovarian cancer cells. Synonyms: L-Lysinamide, N2,N6-bis(L-lysylglycyl-L-valyl-L-seryl-L-leucyl-L-seryl-L-tyrosyl-L-arginyl)-; CTCE-9908; CTCE9908; H-Lys-Gly-Val-Ser-Leu-Ser-Tyr-Arg-Lys(1)-NH2.H-Lys-Gly-Val-Ser-Leu-Ser-Tyr-Arg-(1). Grade: >98%. CAS No. 1030384-98-5. Molecular formula: C86H147N27O23. Mole weight: 1927.27.
CTCE 9908
CTCE 9908. Group: Biochemicals. Grades: Purified. CAS No. 1030384-98-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
C-telopeptide
C-telopeptide, also called as CTX, is a cross-linked peptide of type I collagen and an RIA based on monoclonal antibody raised against this 8-amino-acid sequence was developed. C-telopeptide is released during bone resorption and has been correlated with bone mineral density (BMD). Synonyms: H-Glu-Lys-Ala-His-Asp-Gly-Gly-Arg-OH; L-alpha-glutamyl-L-lysyl-L-alanyl-L-histidyl-L-alpha-aspartyl-glycyl-glycyl-L-arginine; (2S,11S,14S,17S,20S,23S)-14-((1H-imidazol-4-yl)methyl)-23-amino-20-(4-aminobutyl)-11-(carboxymethyl)-2-(3-guanidinopropyl)-17-methyl-4,7,10,13,16,19,22-heptaoxo-3,6,9,12,15,18,21-heptaazahexacosane-1,26-dioic acid; CTX. Grade: ≥95%. CAS No. 162929-64-8. Molecular formula: C34H56N14O13. Mole weight: 868.89.
C-telopeptide acetate
C-telopeptide, also called as CTX, is a cross-linked peptide of type I collagen. C-telopeptide is released during bone resorption and has been correlated with bone mineral density (BMD). Synonyms: CTX acetate. Molecular formula: C36H60N14O15. Mole weight: 928.95.
CTEP
CTEP (RO 4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, and shows > 1000-fold selectivity over other mGlu receptors. CTEP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RO 4956371; mGluR5 inhibitor. CAS No. 871362-31-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15445.
CTEP
CTEP is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor (IC50=2.2 nM), showing >1000-fold selectivity over other mGlu receptors. Synonyms: RO4956371; RO-4956371; RO 4956371; CTEP. Grade: >98%. CAS No. 871362-31-1. Molecular formula: C19H13ClF3N3O. Mole weight: 391.77.
C-terminal processing peptidase
Proteolytic processing of the D1 protein of photosystem II is necessary to allow the light-driven assembly of the tetranuclear manganese cluster, which is responsible for photosynthetic water oxidation. The recognition of the substrate is mediated by a PDZ domain, a small protein module that promotes protein-protein interactions by binding to internal or C-terminal sequences of their partner proteins. Type example of peptidase family S41. Group: Enzymes. Synonyms: CtpA gene product (Synechocystis sp.); photosystem II D1 protein processing peptidase; protease Re; tail-specific protease; Tsp protease. Enzyme Commission Number: EC 3.4.21.102. CAS No. 216484-75-2, 92480-11-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4097; C-terminal processing peptidase; EC 3.4.21.102; 216484-75-2, 92480-11-0; CtpA gene product (Synechocystis sp.); photosystem II D1 protein processing peptidase; protease Re; tail-specific protease; Tsp protease. Cat No: EXWM-4097.
CTK8A3536 is an androgen receptor inhibitor. Synonyms: 5-Thiazolemethanol, 2-(4-morpholinyl)-4-phenyl-; 2-(4-Morpholinyl)-4-phenyl-5-thiazolemethanol; [2-(Morpholin-4-yl)-4-phenyl-1,3-thiazol-5-yl]methanol; (2-morpholino-4-phenylthiazol-5-yl)methanol; Androgen receptor-IN-3; CTK-8A3536, CTK 8A3536. Grade: ≥95%. CAS No. 926228-58-2. Molecular formula: C14H16N2O2S. Mole weight: 276.35.
CTLA-4 inhibitor
CTLA-4 inhibitor is an inhibitor of CTLA-4, an immune checkpoint negatively regulating T cell function. CTLA-4 is thought to regulate T-cell proliferation early in an immune response, primarily in lymph nodes. Synonyms: MDK24720; MDK 24720; MDK-24720; CTLA-4 inhibitor. 2-(4-Fluorophenyl)-6-methyl-4-(3-(trifluoromethyl)phenyl)-1,2-dihydrodipyrazolo[3,4-b:3',4'-d]pyridin-3(6H)-one; EX-A913. CAS No. 635324-72-0. Molecular formula: C21H13F4N5O. Mole weight: 427.363.
cTMP
cTMP (2?,3?-dideoxy-3?-thiothymidine) is an exceptional biomedical compound ubiquitously applied in studying the pernicious Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS). Functioning as a high-potency antiretroviral compound, cTMP exercises its efficacious mechanism by adeptly obstructing the pernicious reverse transcriptase enzyme. Synonyms: Thymidine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. CAS No. 76567-90-3. Molecular formula: C10H12N2O7P · Na. Mole weight: 326.2.
CTNNB1 (29-37)
CTNNB1 anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Synonyms: Catenin Beta 1 (29-37).
CTOP
CTOP. Group: Biochemicals. Grades: Purified. CAS No. 103429-31-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CTOP
CTOP has been found to be an effective and selective μ opioid receptor antagonist and could be used in the treatment of pain. Synonyms: D-Phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-ornithyl-L-threonyl-3-mercapto-L-valyl-L-threoninamide Cyclic (2→7)?-Disulfide. Grade: 98%. CAS No. 103429-31-8. Molecular formula: C50H67N11O11S2. Mole weight: 1062.28.
CTOP (Mu Opioid Receptor Antagonist, CTOP)
A potent antagonist highly selective for Mu opioid receptor (Ki = 0.96nM for u receptor and > 10,000nM for delta receptors). Often used for studying the functional roles of Mu opioid receptors in both central and peripheral nervous systems. Group: Biochemicals. Grades: Highly Purified. CAS No. 103429-31-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
CTOP trifluoroacetate salt
CTOP is a peptide that acts as a selective antagonist of the μ-opioid receptor (IC50 = 2.8 nM). CTOP inhibits the antinociceptive effect of morphine in the tail flick test in mice (ED50 = 0.018 nmol) and reverses morphine-induced increases in locomotor activity (ED50 = 0.02 nmol). Synonyms: Phe-Cys-Tyr-Trp-Orn-Thr-Pen-Thr; D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-ornithyl-L-threonyl-3-mercapto-L-valyl-L-threoninamide-cyclic (2→7)-disulfide trifluoroacetate salt. Grade: ≥98%. Molecular formula: C50H67N11O11S2·xCF3COOH. Mole weight: 1062.3 (free base).
CTP
CTP (cardiac targeting peptide) can transduce cardiomyocytes in vitro. CTP leads to efficient and specific transduction of heart tissue in mice model. CTP can be reversibly linked (e.g. via enolases, thiol groups) to cargo (e.g. miRNAs) for delivery specifically to cardiomyocytes over all other organs[1][2]. Uses: Scientific research. Category: Peptides. Alternative Names: Cardiac targeting peptide. CAS No. 1052692-86-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P4094.
CTP, 100mM Sodium Solution
The solution form of CTP. CTP is a P2X purinergic receptor agonist that can be used in the synthesis of RNA. In metabolic reactions, it acts as a coenzyme. Synonyms: Cytidine 5'-triphosphate, Sodium salt. Grade: ≥ 99% by HPLC. Molecular formula: C9H16N3O14P3 (free acid). Mole weight: 483.16 (free acid).
CTP-347
CTP-347 is a labelled analogue of Paroxetine. CTP-347 was developed for the treatment of hot flashes yet the phase I clinical trial was halted in 2013. Synonyms: Paroxetine-d2. CAS No. 923932-43-8. Molecular formula: C19H18D2FNO3. Mole weight: 331.38.
CTPαS TEA salt
CTPαS, a molecule activator of soluble guanylate cyclase (sGC), is vying for a preeminent position in the study of nitric oxide signaling pathway. With its therapeutic potential locked and loaded, CTPαS is turning heads in the scientific community, demonstrating potential efficacy in addressing cardiovascular diseases such as hypertension and pulmonary arterial hypertension, as well as a wide range of central nervous system conditions, including neurodegenerative diseases and pain management alike. Synonyms: Cytidine, 5'→P''-ester with thiotriphosphoric acid TEA salt; Cytidine-5'-O-(1-thiotriphosphate) TEA salt; CTP-αS TEA salt; Cytidine-5'-(α-thio)-triphosphate, TEA salt (1:1 Mixture of Rp and Sp isomers). Grade: ≥95% by HPLC. Molecular formula: C9H16N3O13P3S (free acid). Mole weight: 499.21 (free acid).
CTPB
CTPB is an amide derivative that acts as a selectively activator of the histone acetyltransferase (HAT) p300, with maximal activation at 275 μM. Synonyms: N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxy-6-pentadecyl-benzamide. Grade: ≥98%. CAS No. 586976-24-1. Molecular formula: C31H43ClF3NO2. Mole weight: 554.1.
CTPB
CTPB is a good activator of p300 histone acetyl transferase (HAT) enzyme[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 586976-24-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124960.
CTP-Cys
CTP-Cys is a cysteine attached to CTP (HY-P4094) for peptide conjugation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2300065-35-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P11541.
CTP-dependent riboflavin kinase
This archaeal enzyme differs from EC 2.7.1.26, riboflavin kinase, in using CTP as the donor nucleotide. UTP, but not ATP or GTP, can also act as a phosphate donor but it is at least an order of magnitude less efficient than CTP. Group: Enzymes. Synonyms: Methanocaldococcus jannaschii Mj0056; Mj0056. Enzyme Commission Number: EC 2.7.1.161. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2991; CTP-dependent riboflavin kinase; EC 2.7.1.161; Methanocaldococcus jannaschii Mj0056; Mj0056. Cat No: EXWM-2991.
CTP-γ-AmNS is a fluorescent analogue of CTP that is used for the determination of enzymes specialized to cleave α/β-phosphodiester bonds. Synonyms: Cytidine- 5'- O- triphosphoro- γ- 1- (5- sulfonic acid)naphthylamidate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 84230-52-4. Molecular formula: C19H23N4O16P3S (free acid). Mole weight: 688.4 (free acid).