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| Product | Description | |
|---|---|---|
| CVD Graphene on SiO2 7cmx7cm(Monolayer) | CVD Graphene on SiO2 7cmx7cm(Monolayer). CAS No. 7440-44-0. Product ID: ACM7440440-115. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| CVD Graphene on SiO2 Substrate | CVD Graphene on SiO2 Substrate. |  |
| CVD Graphene on SiO2 Substrate/Wafer | CVD Graphene on SiO2 Substrate/Wafer. Purity: > 99.9%. | |
| CVD Graphene on Si/SiO2 (Graphene Factory) | CVD Graphene on Si/SiO2 (Graphene Factory). | |
| CVD Method Monolayer MoS2 | CVD Method Monolayer MoS2. | |
| CVD Method Monolayer MoS2 Film | CVD Method Monolayer MoS2 Film. | |
| CVD Method Monolayer WS2 | The CVD method monolayer WS2 is a promising member of Alfa Chemistry's family of 2D graphene-like materials. Among 2D materials with tailored morphologies designed to enhance their performance in nanoelectronics, WS2 is a particularly promising candidate. Alfa Chemistry's high quality WS2 layer films can be used as CVD grown films on sapphire, Al2O3 or SiO2 substrates. Whatever your purpose, you will be impressed with the performance and consistent quality of the CVD method monolayer WS2 from us. Mole weight: 247.98 g/mol. Purity: (6N) 99.9999% confirmed. SMILES: S=[W]=S. InChI: InChI=1S/2S.W. | |
| CVD Method Monolayer WSe2 | Tungsten selenide is a member of the group VI transition metal dichalcogenides, an important class of inorganic two-dimensional materials for various applications including photovoltaics, lithium-ion batteries, and FETs. CVD monolayer WSe2 on SiO2 substrate is just one of many advanced 2D materials we prepare and offer. Find high quality monolayer CVD WSe2 at Alfa Chemistry. Trust us to meet all your advanced material needs. Alternative Names: Tungsten selenide, Tungsten diselenide, Tungsten (IV) selenide. Mole weight: 341.76 g/mol. Purity: (6N) 99.9999% confirmed. SMILES: [Se]=[W]=[Se]. InChI: InChI=1S/2Se.W. | |
| CVM-05-002 | CVM-05-002 is a PI5P4K inhibitor, with IC50 values of 0.27 μM and 1.7 μM for PI5P4Kα and PI5P4Kβ, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2428738-43-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153532. |  |
| CVN293 | CVN293 is a selective and brain permeable potassium ion (K+) channel KCNK13 inhibtor with IC50s of 41 nM and 28 nM for hKCNK13 and mKCNK13, respectively. CVN293 potently inhibits the NLRP3-inflammasome mediated production of the proinflammatory cytokine IL-1β in microglia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2815296-08-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-158155. | |
| CVN636 | CVN636 is a potent, orally active and selective mGluR7 allosteric agonist with an EC50 value of 7 nM for hu mGluR7. CVN636 has central nervous system (CNS) permeability[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2226732-62-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153615. | |
| CVN766 | CVN766 is an orally active inhibitor of orexin 1 receptor antagonist with blood-brain permeability with the IC50 values of 8 nM and >10 μM for OX1R and OX2R, respectively. CVN766 can be used for study schizophrenia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1803557-42-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162235. | |
| CVT10216 | CVT10216 is a potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) with IC50 value of 29nM, thereby inhibiting dopamine synthesis. It is active in suppressing alcohol and cocaine use, and anxiety. It has been shown to produce anxiolytic effects in four different rodent models, including a model of repeated alcohol withdrawal-induced anxiety. It increases acetaldehyde after alcohol gavage and inhibits 2-bottle choice alcohol intake in heavy drinking rodents. It prevents operant self-administration and eliminates cue-induced reinstatement of alcohol seeking. It also prevents alcohol-induced increases in NAc DA without changing basal levels. Uses: Cvt10216 is active in suppressing alcohol and cocaine use, and anxiety. Synonyms: CVT-10216; CVT 10216; CVT10216. 3-[[[3-[4-[(Methylsulfonyl)amino]phenyl]-4-oxo-4H-chromen-7-yl]oxy]methyl]benzoic acid; GS 455534. Grade: >98 %. CAS No. 1005334-57-5. Molecular formula: C24H19NO7S. Mole weight: 465.48. |  |
| CVT 10216 | Potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) (IC50 values are 29 and 1300 nM for ALDH2 and ALDH1, respectively). Exhibits anxiolytic effects in rat models. Group: Biochemicals. Alternative Names: 3-[[[3-[4-[ (Methylsulfonyl) amino]phenyl]-4-oxo-4H-1-benzopyran-7-yl]oxy]methyl]benzoic acid. Grades: Highly Purified. CAS No. 1005334-57-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| CVT-10216 | CVT-10216 is a highly selective, reversible aldehyde dehydrogenase-2 (ALDH-2) inhibitor with an IC50 of 29 nM. CVT-10216 also has inhibitory effect of ALDH-1 with an IC50 of 1.3 μM. CVT-10216 can reduce excessive alcohol drinking in alcohol-preferring rats and exhibit anxiolytic effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1005334-57-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19801. | |
| CVT-11127 | CVT-11127 is a potent SCD inhibitor. CVT-11127 induces apoposis and arrests the cell cycle at the G1/S phase. CVT-11127 has the potential for the research of lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GS-456332. CAS No. 1018674-83-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113638. | |
| CVT-11127 | CVT-11127 is an inhibitor of stearoylCoA desaturase-1 (SCD1). In human lung cancer cells, CVT-11127 reduced lipid synthesis and impaired proliferation by blocking the progression of cell cycle through the G1/S boundary and by triggering programmed cell death. Synonyms: FMK13918. CAS No. 1018674-83-3. Molecular formula: C25H23Cl2N5O3. Mole weight: 512.39. | |
| CVT-12012 | CVT-12012 is a bio-active chemical compound and is highly potent in a human cell-based (HEPG2) SCD assay with IC50 value of 6nM. Synonyms: CVT-12012; CVT 12012; CVT12012; 2-Hydroxy-N-(2-(3-methyl-2-oxo-7-(((3-(trifluoromethyl)phenyl)methyl)amino)-1,2-dihydroquinoxalin-1-yl)ethyl)acetamide. Grade: 95%. CAS No. 1018675-35-8. Molecular formula: C21H21F3N4O3. Mole weight: 434.41. | |
| CVT-2551 | CVT-2551, a piperazineacetamide derivative, could have been useful in some biological studies. Synonyms: CVT-2551; CVT 2551; CVT2551; RS-89961; RS 89961; RS89961; 1-Piperazineacetamide, 4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-N-(2-(hydroxymethyl)-6-methylphenyl)-. Grade: 98%. CAS No. 172430-44-3. Molecular formula: C24H33N3O5. Mole weight: 443.54. | |
| CVT-2759 | CVT-2759 is a potential partial agonist of A(1)-ADORs, may be used to slow AV nodal conduction. Uses: Adenosine a1 receptor agonists. Synonyms: CVT-2759; CVT 2759; CVT2759; UNII-42E8N8RC9Z. Adenosine, N-((3R)-tetrahydro-3-furanyl)-, 5'-(ethylcarbamate). Grade: ≥98%. CAS No. 342419-10-7. Molecular formula: C17H24N6O6. Mole weight: 408.17. | |
| CVT-313 | A cell-permeable purine analog that acts as a potent, selective, reversible, and ATP-competitive inhibitor of Cdk2 (IC50 = 0.5 μM for Cdk2/A and Cdk2/E; 4.2 μM for Cdk1/B; 215 μM for Cdk4/D1). Inhibits other kinases only at much higher concentrations (IC50 > 1.25 mM for MAPK, PKA, and PKC). Shown to induce tumor cells growth arrest (IC50 = ~1.25-20 μM) in vitro and prevent neointima formation in vivo. Synonyms: CVT 313; NG 26; CVT313; NG26; NG-26; NG26. Grade: 95%. CAS No. 199986-75-9. Molecular formula: C20H28N6O3. Mole weight: 400.47. | |
| CVT-313 | CVT-313 (Cdk2 Inhibitor III) is a potent, selective, reversible, and ATP-competitive inhibitor of CDK2 with IC50 of 0.5 μM. CVT-313 inhibits CDC5L phosphorylation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cdk2 Inhibitor III. CAS No. 199986-75-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15339. | |
| CVT-3248 | CVT-3248, a piperazineacetamide derivative, could be probably effective in some biological studies. Synonyms: L58PM3303I; CVT-3248; CVT 3248; CVT3248; RS-101647; RS 101647; RS101647; 1-Piperazineacetamide, N-(2-(hydroxymethyl)-6-methylphenyl)-. Grade: 98%. CAS No. 172430-50-1. Molecular formula: C14H21N3O2. Mole weight: 263.34. | |
| CVT-3369 | CVT-3369 is an impurity of Ranolazine, which is a medication used to treat heart-related chest pain. Synonyms: RS-91347; 4-[2-Hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetic Acid; Ranolazine Impurity 16; CVT 3369; CVT3369; RS 91347; RS91347; 1-Piperazineacetic acid, 4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-. Grade: 98%. CAS No. 172430-48-7. Molecular formula: C16H24N2O5. Mole weight: 324.37. | |
| CVT5440 | CVT5440 is a selective, high affinity A(2B) adenosine receptor antagonist. It may has the potential treatment of asthma and has good selectivity. Uses: Cvt5440 may has the potential treatment of asthma and has good selectivity. Synonyms: CVT-5440; CVT5440; CVT 5440; UNII-29S2U9DRGS; 1H-Purine-2,6-dione, 3,7-dihydro-8-(4-((5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl)methoxy)phenyl)-1,3-dipropyl-; 8-[4-[[5-(3-Methoxyphenyl)-1,2,4-oxadiazol-3-yl]methoxy]phenyl]-1,3-dipropyl-7H-purine-2,6-dione. Grade: 98%. CAS No. 531506-64-6. Molecular formula: C27H28N6O5. Mole weight: 516.55. | |
| CW 008 | CW 008 is a cAMP/PKA/CREB pathway activator promoting osteogenic differentiation of human bone marrow derived MSCs in vitro, and it also increases bone mass and bone volume density in ovariectomized mice. Uses: Promoting osteogenic differentiation of human bone marrow. Synonyms: CW-008; 4-Fluoro-N-[5-fluoro-6-(5-methoxypyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridin-3-yl]benzamide. Grade: >98%. CAS No. 1134613-19-6. Molecular formula: C21H14F2N6O2. Mole weight: 420.38. | |
| CW-069 | CW-069 Inhibitor. Uses: Scientific use. Product Category: T6209. CAS No. 1594094-64-0. |  |
| CW-069 | CW-069 is a novel and allosteric inhibitor of the microtubule motor protein HSET, it shows statistically significant selectivity over KSP. Synonyms: CW069; CW-069; CW 069. Grade: >98%. CAS No. 1594094-64-0. Molecular formula: C23H21IN2O3. Mole weight: 500.33. | |
| CW-069 | CW-069 is an allosteric inhibitor of microtubule motor protein HSET with an IC50 of 75 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1594094-64-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15857. | |
| CW-3308 | CW-3308 is an orally active BRD9 PROTAC degrader with an DC50 of 92 nM. CW-3308 forms a ternary complex with BRD9 and cereblon to mediate BRD9 degradation. CW-3308 inhibits the viability of synovial sarcoma and rhabdoid tumor cells. CW-3308 reduces BRD9 protein levels in xenograft tumor tissues and suppresses tumor growth in xenograft models. CW-3308 can be used for the research of synovial sarcoma and rhabdoid tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3055592-99-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-159579. | |
| CWHM-1008 | CWHM-1008 is a potent and orally active antimalarial agent. Grade: 99%. CAS No. 2362539-97-5. Molecular formula: C22H26F3N3O. Mole weight: 405.46. | |
| CWHM-12 | CWHM 12 demonstrated high potency against all of the five possible β subunit binding partners (αvβ1, αvβ3, αvβ5, αvβ6 and αvβ8) in in vitro ligand-binding assays, with somewhat less potency against αvβ5 than against the other αv integrins. Treated mice with CCl4 for 3 weeks to establish fibrotic disease and then treated with CWHM 12 or vehicle for the final 3 weeks of CCl4. CWHM12 significantly reduced liver fibrosis even after fibrotic disease had been established. Similar to our findings in the liver, administration of CWHM 12 significantly inhibited progression of pulmonary fibrosis. Synonyms: CWHM12; CWHM 12; CWHM-12. Grade: >98%. CAS No. 1564286-55-0. Molecular formula: C26H32BrN5O6. Mole weight: 590.47. | |
| CWHM-12 | CWHM-12 Inhibitor. Uses: Scientific use. Product Category: TQ0250. CAS No. 1564286-55-0. | |
| CWHM-12 | CWHM-12 is a potent inhibitor of αV integrins with IC50s of 0.2, 0.8, 1.5, and 1.8 nM for αvβ8, αvβ3, αvβ6, and αvβ1. Uses: Scientific research. Category: Signaling pathways. CAS No. 1564286-55-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18644. | |
| CWI1-2 | CWI1-2 is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and shows promising anti-leukemic effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2408590-36-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153274. | |
| CWI1-2 hydrochloride | CWI1-2 hydrochloride is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and shows promising anti-leukemic effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2408590-37-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153274A. | |
| CWP232228 | CWP232228, a highly potent selective Wnt/β-catenin signaling inhibitor, antagonizes binding of β-catenin to T-cell factor (TCF) in the nucleus. CWP232228 suppresses tumor formation and metastasis without toxicity through the inhibition of the growth of breast and liver cancer stem cells (CSCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1144044-02-9. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18959. | |
| CX08005 | CX08005 is a competitive inhibitor of PTP1B (IC50 = 0.781 μM). CX08005 binds catalytic P-loop of enzyme. It exhibits some selectivity for PTP1B over other protein tyrosine phosphatases, except TCPTP. Synonyms: 2-[[[2-(Tetradecyl)phenyl]amino]carbonyl]benzoic acid. Grade: ≥98% by HPLC. CAS No. 1256341-22-6. Molecular formula: C28H39N04. Mole weight: 453.61. | |
| CX-157 | CX-157 is a monoamine oxidase (MAO)-A inhibitor potentially for the treatment of depression and anxiety. Synonyms: CX157; CX 157; Phenoxathiin, 3-fluoro-7-(2,2,2-trifluoroethoxy)-, 10,10-dioxide; TriRima; Tyrima. CAS No. 205187-53-7. Molecular formula: C14H8F4O4S. Mole weight: 348.27. | |
| CX1739 | CX1739 is an orally active, blood-brain barrier permeable, low-efficacy AMPA-glutamate receptor (AMPAR) potentiator. CX1739 enhances excitatory neurotransmission by potentiating glutamate-induced excitatory currents and promoting in vivo long-term potentiation. CX1739 eliminates amphetamine-induced locomotor activity, reverses opioid-, pentobarbital- and ethanol-induced respiratory depression, and exerts pro-cognitive effects in animals. CX1739 impairs motor function recovery and increases the risk of post-injury complications. CX1739 can be used in research related to attention-deficit/hyperactivity disorder, dementia, respiratory depression and spinal cord injury[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1086377-48-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-171844. | |
| CX 4945 hydrochloride | CX 4945 hydrochloride is an orally bioactive and ATP-competitive casein kinase 2 (CK2) inhibitor. CX 4945 inhibits proliferation and migration in a panel of cancer cell lines which overexpresses CK2. Uses: Antitumor agent. Synonyms: CX 4945 hydrochloride; CX-4945 hydrochloride; CX4945 hydrochloride; Silmitasertib HCl; Silmitasertib hydrochloride. Grade: 98%. CAS No. 2108312-01-0. Molecular formula: C19H12ClN3O2.HCl. Mole weight: 386.23. | |
| CX-4945 sodium salt | CX-4945 (Silmitasertib) sodium salt is a potent and selective ATP-competitive small molecule protein kinase CK2 inhibitor with a Ki and an IC50 of 0.38 and 1 nM for recombinant human CK2α, respectively. Synonyms: Silmitasertib sodium salt; CX-4945 sodium salt; CX 4945 sodium salt; CX4945 sodium salt. Grade: >98%. CAS No. 1309357-15-0. Molecular formula: C19H11ClN3NaO2. Mole weight: 371.75. | |
| CX-5011 | CX-5011 is a very potent and selective CK2 inhibitor, which induces cell death in tumor cells. Synonyms: CX5011; CX 5011; Pyrimido[4,5-c]quinoline-8-carboxylic acid, 5-[(3-ethynylphenyl)amino]-. Grade: 98%. CAS No. 1009821-06-0. Molecular formula: C20H12N4O2. Mole weight: 340.34. | |
| CX516 | CX516 (BDP 12) is an ampakine and acts as an AMPA receptor positive allosteric modulator for the research of Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BDP 12. CAS No. 154235-83-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10933. | |
| CX546 | CX546 is a first-generation and selective benzamide-type positive AMPAR modulator. CX546 is a prototypical ampakine agent and has antipsychotic effects[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 215923-54-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12505. | |
| CX546 | It is one of a series of AMPA modulators for the potential treatment of Alzheimer's disease, schizophrenia, and mild cognitive impairment (MCI). An ampakine drug that facilitates activation of glutamatergic AMPA receptors. Synonyms: (2,3-Dihydro-1,4-benzodioxin-6-yl)-1-piperidinylmethanone; 1-[(2,3-Dihydro-1,4-benzodioxin-6-yl)carbonyl]piperidine; CX546; CX 546; CX-546; UNII-PV6YEC8983; GR 87; GR-87; BDP 17; GR87; BDP17; BDP-17. Grade: >98%. CAS No. 215923-54-9. Molecular formula: C14H17NO3. Mole weight: 247.29. | |
| CX 546 | AMPA potentiator. Group: Biochemicals. Alternative Names: (2,3-Dihydro-1,4-benzodioxin-6-yl)-1-piperidinylmethanone. Grades: Highly Purified. CAS No. 215923-54-9. Pack Sizes: 10mg, 50mg. Molecular Formula: C14H17NO3. US Biological Life Sciences. | Worldwide |
| CX-5461 | CX-5461 is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcription of rRNA with IC50 of 142 nM, has no effect on Pol II, and possesses 250- to 300-fold selectivity for inhibition of rRNA transcription versus DNA replication and protein translation. Synonyms: CX-5461; CX 5461; CX5461. CAS No. 1138549-36-6. Molecular formula: C27H27N7O2S. Mole weight: 513.62. | |
| CX-5461 | CX-5461 is a potent and oral rRNA synthesis inhibitor. It inhibits RNA polymerase I-driven transcription of rRNA with IC50s of 142, 113, and 54 nM in HCT-116, A375, and MIA PaCa-2 cells, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1138549-36-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13323. | |
| CX-5461 dihydrochloride | CX-5461 dihydrochloride is a potent and orally bioavailable Pol I-mediated rRNA synthesis inhibitor, with IC50s of 142, 113 and 54 nM in HCT-116, A375 and MIA PaCa-2 cells, respectively. It shows little or no effect on Pol II (IC50 ≥25 μM). Synonyms: 5H-Benzothiazolo[3,2-a][1,8]naphthyridine-6-carboxamide, 2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-N-[(5-methyl-2-pyrazinyl)methyl]-5-oxo-, hydrochloride (1:2). Grade: ≥98%. Molecular formula: C27H29Cl2N7O2S. Mole weight: 586.54. | |
| CX-5461 (Pidnarulex) | Pidnarulex (CX-5461) is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcription of rRNA with IC50 of 142 nM in HCT-116, A375, and MIA PaCa-2 cells, has no effect on Pol II, and possesses 250- to 300-fold selectivity for inhibition of rRNA transcription versus DNA replication and protein translation. Group: Inhibitors. CAS No. 1138549-36-6. Pack Sizes: 5mg. Product ID: S2684. Formula: C27H27N7O2S. Smiles: CC1=CN=C(C=N1)CNC(=O)C2=C3N(C4=CC=CC=C4S3)C5=C(C2=O)C=CC(=N5)N6CCCN(CC6)C. Storage Conditions: 3 years-20°C(in the dark) powder. |  United States; Europe |
| CX614 | CX614 is a positive variant modulator of AMPA receptors that enhances excitatory postsynaptic potentials (amplitude and duration) by blocking and slowing the inactivation of responses to glutamate and automatically evokes excitatory postsynaptic currents in neuronal cultures. CX614 can be used in the study of psychiatric disorders such as depression[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 191744-13-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110175. | |
| CX 614 | CX 614 has been found to be an AMPA modulator and has also been found to be an ampakine drug facilitating activation of glutamatergic AMPA receptors. Synonyms: CX614; CX 614; CX-614. 2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one. Grade: ≥99% by HPLC. CAS No. 191744-13-5. Molecular formula: C13H13NO4. Mole weight: 247.25. | |
| CX 614 | Positive allosteric modulator of AMPA receptors. Group: Biochemicals. Alternative Names: 2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one. Grades: Highly Purified. CAS No. 191744-13-5. Pack Sizes: 10mg, 50mg. Molecular Formula: C13H13NO4. US Biological Life Sciences. | Worldwide |
| CX-6258 | CX-6258 is a potent, orally efficacious Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor with excellent biochemical potency and kinase selectivity. Synonyms: (E)-5-chloro-3-((5-(3-(4-methyl-1,4-diazepane-1-carbonyl)phenyl)furan-2-yl)methylene)indolin-2-one; CX6258; CX-6258; CX 6258. CAS No. 1202916-90-2. Molecular formula: C26H24ClN3O3. Mole weight: 461.946. | |
| CX-6258 hydrochloride | CX-6258 hydrochloride is a potent and kinase selective pan-Pim kinases inhibitor, with IC50s of 5 nM, 25 nM and 16 nM for Pim-1, Pim-2 and Pim-3, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1353859-00-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18095B. | |
| CX-6258 Hydrochloride | CX-6258 shows antiproliferative activity against a panel of human cancer cell lines with IC50 of 0.02-3.7 μM, mostly sensitive to acute leukemia cell lines. Synonyms: CX-6258 HCl; CX 6258 hydrochloride; CX 6258 HCl; CX6258 HCl. Grade: >98%. CAS No. 1353859-00-3. Molecular formula: C26H25Cl2N3O3. Mole weight: 498.40. | |
| CX-6258 hydrochloride hydrate | The hydrochloride hydrate salt form of CX-6258, a pan-Pim kinases inhibitor, has been found to have strong antiproliferative potencies against human solid tumors and hematological malignancies. It has already been discontinued for Solid tumours. IC50: 5 n. Uses: The hydrochloride hydrate salt form of cx-6258 is a pan-pim kinases inhibitor that has been found to have strong antiproliferative potencies against human solid tumors and hematological malignancies. it has already been discontinued for solid tumours. ic5. Synonyms: CX-6258 hydrochloride hydrate; CX 6258 hydrochloride hydrate; CX6258 hydrochloride hydrate; C26H24ClN3O3.ClH.H2O; 2121AH; HY-18095A; CS-1530; W-6143; CS 1530; W 6143; CS1530; W6143. Grade: 98%. CAS No. 1353858-99-7. Molecular formula: C26H27Cl2N3O4. Mole weight: 516.42. | |
| CXCR2 antagonist 2 | CXCR2 antagonist 2, a potent CXCR2 antagonist (IC50 = 95 nM), is used in cancer immunotherapy. Synonyms: 1-(3-fluoro-2-methylphenyl)-3-(8-hydroxy-1,1-dioxo-3,4-dihydro-2H-thiochromen-7-yl)urea. CAS No. 2647464-91-1. Molecular formula: C17H17FN2O4S. Mole weight: 364.39. | |
| CXCR2 antagonist 3 | CXCR2 antagonist 3, a potent CXCR2 antagonist, has double-digit nanomolar potencies against CXCR2 and significantly inhibits neutrophil infiltration into air pouch. It reduces the infiltration of neutrophils and MDSCs, and enhances the infiltration of CD3+ T lymphocytes into Pan02 tumor tissues. Synonyms: Urea, N-(3-fluoro-2-methylphenyl)-N'-(8-hydroxy-1,1-dioxido-2H-1-benzothiopyran-7-yl)-. CAS No. 2647464-92-2. Molecular formula: C17H15FN2O4S. Mole weight: 362.38. | |
| CXCR2-IN-1 | CXCR2-IN-1 is a CXCR2 antagonist (pIC50 = 9.3) with favorable central nervous system penetration property (Br/Bl>0.45). Synonyms: 1-(2-chloro-3-fluorophenyl)-3-[4-chloro-2-hydroxy-3-(1-methylpiperidin-4-yl)sulfonylphenyl]urea. CAS No. 1873376-49-8. Molecular formula: C19H20Cl2FN3O4S. Mole weight: 476.35. | |
| CXCR2-IN-2 | CXCR2-IN-2 is a selective, brain penetrant and orally bioavailable CXCR2 antagonist with IC50s of 5.2 and 1 nM in β-arrestin assay and CXCR2 Tango assay, respectively. It inhibits human whole blood Gro-α induced CD11b expression (IC50 = 0.04 μM). It shows ~730-fold selectivity over CXCR1 and >1900-fold selectivity over all other chemokine receptors. Synonyms: 1-(4-Chloro-2-hydroxy-3-(((S)-3-methyltetrahydrofuran-3-yl)sulfonyl)phenyl)-3-((R)-2-methylcyclopent-2-en-1-yl)urea; 1-(4-Chloro-2-hydroxy-3-{[(3S)-3-methyltetrahydro-3-furanyl]sulfonyl}phenyl)-3-[(1R)-2-methyl-2-cyclopenten-1-yl]urea. Grade: ≥95%. CAS No. 1838123-21-9. Molecular formula: C18H23ClN2O5S. Mole weight: 414.90. | |
| CXCR301 | CXCR301. Molecular formula: C36H47N9O6. Mole weight: 701.80. | |
| CXCR3 Antagonist 6c | CXCR3 Antagonist 6c is a potent and selective chemokine CXCR3 antagonist (IC50 value of 60 nM in a calcium mobilization functional assay). It inhibits CXCR3 functional response to CXCL11 as measured by T-cell chemotaxis. Synonyms: 4-[2-[(3-chlorobenzoyl)amino]-4-[2-(2,4-dichlorophenyl)ethylcarbamoyl]phenyl]-N-ethyl-1,4-diazepane-1-carboxamide. Grade: 99%. CAS No. 870998-13-3. Molecular formula: C30H32Cl3N5O3. Mole weight: 616.97. | |
| CXCR4 antagonist 1 | CXCR4 antagonist 1 is a potent CXCR4 antagonist with anti-HIV activity. Synonyms: 1,4-Butanediamine, N4-[[4-[[(1H-imidazol-2-ylmethyl)[(1-methyl-1H-imidazol-2-yl)methyl]amino]methyl]phenyl]methyl]-N1,N1-dipropyl-; N-(4-{[(1H-imidazol-2-ylmethyl)-(1-methyl-1H-imidazol-2-ylmethyl)-amino]-methyl}-benzyl)-N',N'-dipropyl-butane-1,4-diamine. Grade: ≥98% (HPLC). CAS No. 675135-69-0. Molecular formula: C27H43N7. Mole weight: 465.68. | |
| CXCR4 antagonist 2 | CXCR4 antagonist 2 is an antagonist of CXCR4 with an IC50 of 47 nM. Synonyms: (S)-N-methyl-N-(((R)-5-((4-methylpiperazin-1-yl)amino)-1,2,3,4-tetrahydroisoquinolin-3-yl)methyl)-5,6,7,8-tetrahydroquinolin-8-amine. CAS No. 2243636-57-7. Molecular formula: C25H36N6. Mole weight: 420.59. | |
| CXCR7 antagonist-1 | CXCR7 antagonist-1 is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. CXCR7 antagonist-1 is useful in preventing tumor cell proliferation, tumor formation, inflammatory diseases, and many other diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1613021-99-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139643. | |
| CXCR7 antagonist-1 hydrochloride | CXCR7 antagonist-1 hydrochloride is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. CXCR7 antagonist-1 hydrochloride is useful in preventing tumor cell proliferation, tumor formation, inflammatory diseases, and many other diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2990472-61-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139643A. | |
| CXCR7 modulator 1 | CXCR7 modulator 1 (compound 25) is a potent and orally bioavailable peptoid hybrid CXCR7 modulator, with a Ki of 9 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2231812-31-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107987. | |
| CXCR7 modulator 1 | CXCR7 modulator 1 is a potent and orally bioavailable peptoid hybrid CXCR7 modulator, with a Ki of 9 nM. Synonyms: cyclo[Ala(tBu)-Tza-D-Pro-N(Unk)Gly-Ser(Bn)-D-Phe]; Cyclo{3-(1,3-thiazol-4-yl)-L-alanyl-D-prolyl-N-[3-(2,4-difluorophenyl)propyl]glycyl-O-benzyl-L-seryl-D-phenylalanyl-4-methyl-L-leucyl}. Grade: ≥95%. CAS No. 2231812-31-8. Molecular formula: C48H57F2N7O7S. Mole weight: 914.07. | |
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