A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
CW-069 is an allosteric inhibitor of microtubule motor protein HSET with an IC50 of 75 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1594094-64-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15857.
CW-3308
CW-3308 is an orally active BRD9 PROTAC degrader with an DC50 of 92 nM. CW-3308 forms a ternary complex with BRD9 and cereblon to mediate BRD9 degradation. CW-3308 inhibits the viability of synovial sarcoma and rhabdoid tumor cells. CW-3308 reduces BRD9 protein levels in xenograft tumor tissues and suppresses tumor growth in xenograft models. CW-3308 can be used for the research of synovial sarcoma and rhabdoid tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3055592-99-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-159579.
CWHM-1008
CWHM-1008 is a potent and orally active antimalarial agent. Grade: 99%. CAS No. 2362539-97-5. Molecular formula: C22H26F3N3O. Mole weight: 405.46.
CWHM-12
CWHM-12 is a potent inhibitor of αV integrins with IC50s of 0.2, 0.8, 1.5, and 1.8 nM for αvβ8, αvβ3, αvβ6, and αvβ1. Uses: Scientific research. Category: Signaling pathways. CAS No. 1564286-55-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18644.
CWHM 12 demonstrated high potency against all of the five possible β subunit binding partners (αvβ1, αvβ3, αvβ5, αvβ6 and αvβ8) in in vitro ligand-binding assays, with somewhat less potency against αvβ5 than against the other αv integrins. Treated mice with CCl4 for 3 weeks to establish fibrotic disease and then treated with CWHM 12 or vehicle for the final 3 weeks of CCl4. CWHM12 significantly reduced liver fibrosis even after fibrotic disease had been established. Similar to our findings in the liver, administration of CWHM 12 significantly inhibited progression of pulmonary fibrosis. Synonyms: CWHM12; CWHM 12; CWHM-12. Grade: >98%. CAS No. 1564286-55-0. Molecular formula: C26H32BrN5O6. Mole weight: 590.47.
CWI1-2
CWI1-2 is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and shows promising anti-leukemic effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2408590-36-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153274.
CWI1-2 hydrochloride
CWI1-2 hydrochloride is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and shows promising anti-leukemic effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2408590-37-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153274A.
CWP232228
CWP232228, a highly potent selective Wnt/β-catenin signaling inhibitor, antagonizes binding of β-catenin to T-cell factor (TCF) in the nucleus. CWP232228 suppresses tumor formation and metastasis without toxicity through the inhibition of the growth of breast and liver cancer stem cells (CSCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1144044-02-9. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-18959.
CX08005
CX08005 is a competitive inhibitor of PTP1B (IC50 = 0.781 μM). CX08005 binds catalytic P-loop of enzyme. It exhibits some selectivity for PTP1B over other protein tyrosine phosphatases, except TCPTP. Synonyms: 2-[[[2-(Tetradecyl)phenyl]amino]carbonyl]benzoic acid. Grade: ≥98% by HPLC. CAS No. 1256341-22-6. Molecular formula: C28H39N04. Mole weight: 453.61.
CX-157
CX-157 is a monoamine oxidase (MAO)-A inhibitor potentially for the treatment of depression and anxiety. Synonyms: CX157; CX 157; Phenoxathiin, 3-fluoro-7-(2,2,2-trifluoroethoxy)-, 10,10-dioxide; TriRima; Tyrima. CAS No. 205187-53-7. Molecular formula: C14H8F4O4S. Mole weight: 348.27.
CX1739
CX1739 is an orally active, blood-brain barrier permeable, low-efficacy AMPA-glutamate receptor (AMPAR) potentiator. CX1739 enhances excitatory neurotransmission by potentiating glutamate-induced excitatory currents and promoting in vivo long-term potentiation. CX1739 eliminates amphetamine-induced locomotor activity, reverses opioid-, pentobarbital- and ethanol-induced respiratory depression, and exerts pro-cognitive effects in animals. CX1739 impairs motor function recovery and increases the risk of post-injury complications. CX1739 can be used in research related to attention-deficit/hyperactivity disorder, dementia, respiratory depression and spinal cord injury[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1086377-48-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-171844.
CX 4945 hydrochloride
CX 4945 hydrochloride is an orally bioactive and ATP-competitive casein kinase 2 (CK2) inhibitor. CX 4945 inhibits proliferation and migration in a panel of cancer cell lines which overexpresses CK2. Uses: Antitumor agent. Synonyms: CX 4945 hydrochloride; CX-4945 hydrochloride; CX4945 hydrochloride; Silmitasertib HCl; Silmitasertib hydrochloride. Grade: 98%. CAS No. 2108312-01-0. Molecular formula: C19H12ClN3O2.HCl. Mole weight: 386.23.
CX-4945 sodium salt
CX-4945 (Silmitasertib) sodium salt is a potent and selective ATP-competitive small molecule protein kinase CK2 inhibitor with a Ki and an IC50 of 0.38 and 1 nM for recombinant human CK2α, respectively. Synonyms: Silmitasertib sodium salt; CX-4945 sodium salt; CX 4945 sodium salt; CX4945 sodium salt. Grade: >98%. CAS No. 1309357-15-0. Molecular formula: C19H11ClN3NaO2. Mole weight: 371.75.
CX-5011
CX-5011 is a very potent and selective CK2 inhibitor, which induces cell death in tumor cells. Synonyms: CX5011; CX 5011; Pyrimido[4,5-c]quinoline-8-carboxylic acid, 5-[(3-ethynylphenyl)amino]-. Grade: 98%. CAS No. 1009821-06-0. Molecular formula: C20H12N4O2. Mole weight: 340.34.
CX516
CX516 (BDP 12) is an ampakine and acts as an AMPA receptor positive allosteric modulator for the research of Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BDP 12. CAS No. 154235-83-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-10933.
CX546
It is one of a series of AMPA modulators for the potential treatment of Alzheimer's disease, schizophrenia, and mild cognitive impairment (MCI). An ampakine drug that facilitates activation of glutamatergic AMPA receptors. Synonyms: (2,3-Dihydro-1,4-benzodioxin-6-yl)-1-piperidinylmethanone; 1-[(2,3-Dihydro-1,4-benzodioxin-6-yl)carbonyl]piperidine; CX546; CX 546; CX-546; UNII-PV6YEC8983; GR 87; GR-87; BDP 17; GR87; BDP17; BDP-17. Grade: >98%. CAS No. 215923-54-9. Molecular formula: C14H17NO3. Mole weight: 247.29.
CX546
CX546 is a first-generation and selective benzamide-type positive AMPAR modulator. CX546 is a prototypical ampakine agent and has antipsychotic effects[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 215923-54-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12505.
CX 546
AMPA potentiator. Group: Biochemicals. Alternative Names: (2,3-Dihydro-1,4-benzodioxin-6-yl)-1-piperidinylmethanone. Grades: Highly Purified. CAS No. 215923-54-9. Pack Sizes: 10mg, 50mg. Molecular Formula: C14H17NO3. US Biological Life Sciences.
Worldwide
CX-5461
CX-5461 is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcription of rRNA with IC50 of 142 nM, has no effect on Pol II, and possesses 250- to 300-fold selectivity for inhibition of rRNA transcription versus DNA replication and protein translation. Synonyms: CX-5461; CX 5461; CX5461. CAS No. 1138549-36-6. Molecular formula: C27H27N7O2S. Mole weight: 513.62.
CX-5461
CX-5461 is a potent and oral rRNA synthesis inhibitor. It inhibits RNA polymerase I-driven transcription of rRNA with IC50s of 142, 113, and 54 nM in HCT-116, A375, and MIA PaCa-2 cells, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1138549-36-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13323.
CX-5461 dihydrochloride
CX-5461 dihydrochloride is a potent and orally bioavailable Pol I-mediated rRNA synthesis inhibitor, with IC50s of 142, 113 and 54 nM in HCT-116, A375 and MIA PaCa-2 cells, respectively. It shows little or no effect on Pol II (IC50 ≥25 μM). Synonyms: 5H-Benzothiazolo[3,2-a][1,8]naphthyridine-6-carboxamide, 2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-N-[(5-methyl-2-pyrazinyl)methyl]-5-oxo-, hydrochloride (1:2). Grade: ≥98%. Molecular formula: C27H29Cl2N7O2S. Mole weight: 586.54.
CX-5461 (Pidnarulex)
Pidnarulex (CX-5461) is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcription of rRNA with IC50 of 142 nM in HCT-116, A375, and MIA PaCa-2 cells, has no effect on Pol II, and possesses 250- to 300-fold selectivity for inhibition of rRNA transcription versus DNA replication and protein translation. Group: Inhibitors. CAS No. 1138549-36-6. Pack Sizes: 5mg. Product ID: S2684. Formula: C27H27N7O2S. Smiles: CC1=CN=C(C=N1)CNC(=O)C2=C3N(C4=CC=CC=C4S3)C5=C(C2=O)C=CC(=N5)N6CCCN(CC6)C. Storage Conditions: 3 years-20°C(in the dark) powder.
United States; Europe
CX614
CX614 is a positive variant modulator of AMPA receptors that enhances excitatory postsynaptic potentials (amplitude and duration) by blocking and slowing the inactivation of responses to glutamate and automatically evokes excitatory postsynaptic currents in neuronal cultures. CX614 can be used in the study of psychiatric disorders such as depression[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 191744-13-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110175.
CX 614
Positive allosteric modulator of AMPA receptors. Group: Biochemicals. Alternative Names: 2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one. Grades: Highly Purified. CAS No. 191744-13-5. Pack Sizes: 10mg, 50mg. Molecular Formula: C13H13NO4. US Biological Life Sciences.
Worldwide
CX 614
CX 614 has been found to be an AMPA modulator and has also been found to be an ampakine drug facilitating activation of glutamatergic AMPA receptors. Synonyms: CX614; CX 614; CX-614. 2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-one. Grade: ≥99% by HPLC. CAS No. 191744-13-5. Molecular formula: C13H13NO4. Mole weight: 247.25.
CX-6258
CX-6258 is a potent, orally efficacious Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor with excellent biochemical potency and kinase selectivity. Synonyms: (E)-5-chloro-3-((5-(3-(4-methyl-1,4-diazepane-1-carbonyl)phenyl)furan-2-yl)methylene)indolin-2-one; CX6258; CX-6258; CX 6258. CAS No. 1202916-90-2. Molecular formula: C26H24ClN3O3. Mole weight: 461.946.
CX-6258 hydrochloride
CX-6258 hydrochloride is a potent and kinase selective pan-Pim kinases inhibitor, with IC50s of 5 nM, 25 nM and 16 nM for Pim-1, Pim-2 and Pim-3, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1353859-00-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18095B.
CX-6258 Hydrochloride
CX-6258 shows antiproliferative activity against a panel of human cancer cell lines with IC50 of 0.02-3.7 μM, mostly sensitive to acute leukemia cell lines. Synonyms: CX-6258 HCl; CX 6258 hydrochloride; CX 6258 HCl; CX6258 HCl. Grade: >98%. CAS No. 1353859-00-3. Molecular formula: C26H25Cl2N3O3. Mole weight: 498.40.
CX-6258 hydrochloride hydrate
The hydrochloride hydrate salt form of CX-6258, a pan-Pim kinases inhibitor, has been found to have strong antiproliferative potencies against human solid tumors and hematological malignancies. It has already been discontinued for Solid tumours. IC50: 5 n. Uses: The hydrochloride hydrate salt form of cx-6258 is a pan-pim kinases inhibitor that has been found to have strong antiproliferative potencies against human solid tumors and hematological malignancies. it has already been discontinued for solid tumours. ic5. Synonyms: CX-6258 hydrochloride hydrate; CX 6258 hydrochloride hydrate; CX6258 hydrochloride hydrate; C26H24ClN3O3.ClH.H2O; 2121AH; HY-18095A; CS-1530; W-6143; CS 1530; W 6143; CS1530; W6143. Grade: 98%. CAS No. 1353858-99-7. Molecular formula: C26H27Cl2N3O4. Mole weight: 516.42.
CXCR2 antagonist 2
CXCR2 antagonist 2, a potent CXCR2 antagonist (IC50 = 95 nM), is used in cancer immunotherapy. Synonyms: 1-(3-fluoro-2-methylphenyl)-3-(8-hydroxy-1,1-dioxo-3,4-dihydro-2H-thiochromen-7-yl)urea. CAS No. 2647464-91-1. Molecular formula: C17H17FN2O4S. Mole weight: 364.39.
CXCR2 antagonist 3
CXCR2 antagonist 3, a potent CXCR2 antagonist, has double-digit nanomolar potencies against CXCR2 and significantly inhibits neutrophil infiltration into air pouch. It reduces the infiltration of neutrophils and MDSCs, and enhances the infiltration of CD3+ T lymphocytes into Pan02 tumor tissues. Synonyms: Urea, N-(3-fluoro-2-methylphenyl)-N'-(8-hydroxy-1,1-dioxido-2H-1-benzothiopyran-7-yl)-. CAS No. 2647464-92-2. Molecular formula: C17H15FN2O4S. Mole weight: 362.38.
CXCR2-IN-1
CXCR2-IN-1 is a CXCR2 antagonist (pIC50 = 9.3) with favorable central nervous system penetration property (Br/Bl>0.45). Synonyms: 1-(2-chloro-3-fluorophenyl)-3-[4-chloro-2-hydroxy-3-(1-methylpiperidin-4-yl)sulfonylphenyl]urea. CAS No. 1873376-49-8. Molecular formula: C19H20Cl2FN3O4S. Mole weight: 476.35.
CXCR2-IN-2
CXCR2-IN-2 is a selective, brain penetrant and orally bioavailable CXCR2 antagonist with IC50s of 5.2 and 1 nM in β-arrestin assay and CXCR2 Tango assay, respectively. It inhibits human whole blood Gro-α induced CD11b expression (IC50 = 0.04 μM). It shows ~730-fold selectivity over CXCR1 and >1900-fold selectivity over all other chemokine receptors. Synonyms: 1-(4-Chloro-2-hydroxy-3-(((S)-3-methyltetrahydrofuran-3-yl)sulfonyl)phenyl)-3-((R)-2-methylcyclopent-2-en-1-yl)urea; 1-(4-Chloro-2-hydroxy-3-{[(3S)-3-methyltetrahydro-3-furanyl]sulfonyl}phenyl)-3-[(1R)-2-methyl-2-cyclopenten-1-yl]urea. Grade: ≥95%. CAS No. 1838123-21-9. Molecular formula: C18H23ClN2O5S. Mole weight: 414.90.
CXCR3 Antagonist 6c is a potent and selective chemokine CXCR3 antagonist (IC50 value of 60 nM in a calcium mobilization functional assay). It inhibits CXCR3 functional response to CXCL11 as measured by T-cell chemotaxis. Synonyms: 4-[2-[(3-chlorobenzoyl)amino]-4-[2-(2,4-dichlorophenyl)ethylcarbamoyl]phenyl]-N-ethyl-1,4-diazepane-1-carboxamide. Grade: 99%. CAS No. 870998-13-3. Molecular formula: C30H32Cl3N5O3. Mole weight: 616.97.
CXCR4 antagonist 1
CXCR4 antagonist 1 is a potent CXCR4 antagonist with anti-HIV activity. Synonyms: 1,4-Butanediamine, N4-[[4-[[(1H-imidazol-2-ylmethyl)[(1-methyl-1H-imidazol-2-yl)methyl]amino]methyl]phenyl]methyl]-N1,N1-dipropyl-; N-(4-{[(1H-imidazol-2-ylmethyl)-(1-methyl-1H-imidazol-2-ylmethyl)-amino]-methyl}-benzyl)-N',N'-dipropyl-butane-1,4-diamine. Grade: ≥98% (HPLC). CAS No. 675135-69-0. Molecular formula: C27H43N7. Mole weight: 465.68.
CXCR4 antagonist 2
CXCR4 antagonist 2 is an antagonist of CXCR4 with an IC50 of 47 nM. Synonyms: (S)-N-methyl-N-(((R)-5-((4-methylpiperazin-1-yl)amino)-1,2,3,4-tetrahydroisoquinolin-3-yl)methyl)-5,6,7,8-tetrahydroquinolin-8-amine. CAS No. 2243636-57-7. Molecular formula: C25H36N6. Mole weight: 420.59.
CXCR7 antagonist-1
CXCR7 antagonist-1 is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. CXCR7 antagonist-1 is useful in preventing tumor cell proliferation, tumor formation, inflammatory diseases, and many other diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1613021-99-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139643.
CXCR7 antagonist-1 hydrochloride
CXCR7 antagonist-1 hydrochloride is a CXCR7 antagonist that inhibits the binding of the SDF-1 chemokine (also known as the CXCL12 chemokine) or I-TAC (also known as CXCL11) to the chemokine receptor CXCR7. CXCR7 antagonist-1 hydrochloride is useful in preventing tumor cell proliferation, tumor formation, inflammatory diseases, and many other diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2990472-61-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139643A.
CXCR7 modulator 1
CXCR7 modulator 1 (compound 25) is a potent and orally bioavailable peptoid hybrid CXCR7 modulator, with a Ki of 9 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2231812-31-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107987.
CXCR7 modulator 1
CXCR7 modulator 1 is a potent and orally bioavailable peptoid hybrid CXCR7 modulator, with a Ki of 9 nM. Synonyms: cyclo[Ala(tBu)-Tza-D-Pro-N(Unk)Gly-Ser(Bn)-D-Phe]; Cyclo{3-(1,3-thiazol-4-yl)-L-alanyl-D-prolyl-N-[3-(2,4-difluorophenyl)propyl]glycyl-O-benzyl-L-seryl-D-phenylalanyl-4-methyl-L-leucyl}. Grade: ≥95%. CAS No. 2231812-31-8. Molecular formula: C48H57F2N7O7S. Mole weight: 914.07.
CXCR7 modulator 2
CXCR7 modulator 2 is a CXC Chemokine Receptor Type 7 (CXCR7) modulator, with a Ki of 13 nM. Synonyms: 1H-1,4-Diazepine-1-propanamide, 4-(7-ethylimidazo[1,2-a]pyridin-8-yl)hexahydro-β-[1-[(1R,2S,4S)-7-oxabicyclo[2.2.1]hept-2-ylcarbonyl]-4-piperidinyl]-, (βS)-; (3S)-3-[4-(7-Ethylimidazo[1,2-a]pyridin-8-yl)-1,4-diazepan-1-yl]-3-{1-[(1R,2S,4S)-7-oxabicyclo[2.2.1]hept-2-ylcarbonyl]-4-piperidinyl}propanamide. Grade: ≥98%. CAS No. 2227426-37-9. Molecular formula: C29H42N6O3. Mole weight: 522.68.
CXCR7 modulator 2
CXCR7 modulator 2 is a modulator of C-X-C Chemokine Receptor Type 7 (CXCR7), with a Ki of 13 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 2227426-37-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112154.
CXD101
CXD101 is a selective histone deacetylase (HDAC) inhibitor with IC50 of 63 nM, 570 nM and 550 nM for HDAC1, HDAC2 and HDAC3, respectively. It exhibits antineoplastic activity. Synonyms: HDAC-IN-4; CXD-101; CXD 101; N-(2-Aminophenyl)-4-(1-((1,3-dimethyl-1H-pyrazol-4-yl)methyl)piperidin-4-yl)benzamide. Grade: 99%. CAS No. 934828-12-3. Molecular formula: C24H29N5O. Mole weight: 403.52.
CXL146
CXL146 is a 4H-Chromene derivative that eliminates cancer cells with GRP78 overexpression via activating unfolded protein response-mediated apoptosis. Synonyms: Prop-2-ynyl 2-amino-6-(2-methylpyridin-4-yl)-4-(2-oxo-2-(prop-2-ynyloxy)ethyl)-4H-chromene-3-carboxylate. Grade: 99%. CAS No. 2244586-41-0. Molecular formula: C24H20N2O5. Mole weight: 416.43.
cXMP
cXMP, a highly potent biomolecular tool, serves as a remarkable resource in the field of biomedicine due to its diverse applications. Its immense value lies in its prowess as a cyclic nucleotide analog, granting researchers the ability to delve deep into the intricate web of signaling pathways associated with cellular responses, encompassing the realm of drugs and diseases. Pertaining to research and drug discovery, cXMP assumes a pivotal role in unraveling the intricacies of cyclic nucleotide involvement in the regulation of various biochemical processes. Synonyms: Xanthosine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. CAS No. 31319-70-7. Molecular formula: C10H10N4O8P · Na. Mole weight: 368.2.
CX Tool Steel Powder
CX Tool Steel Powder.
CY-09
CY-09 is a selective and direct NLRP3 inhibitor. CY-09 directly binds to the ATP-binding motif of NLRP3 NACHT domain and inhibits NLRP3 ATPase activity, resulting in the suppression of NLRP3 inflammasome assembly and activation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1073612-91-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103666.
CY 208-243
CY 208-243 is a D1DR receptor agonist and has been found to show antiparkinsonian activity in animal models. Synonyms: CY 208-243; CY-208-243; CY208243; (-)-(6aR,12bR)-4,6,6a,7,8,12b-Hexahydro-7-methylindolo[4,3-a]phenanthridin. Grade: ≥95% by HPLC. CAS No. 100999-26-6. Molecular formula: C19H18N2. Mole weight: 274.36.
Cy2-SE (iodine)
Cy2-SE iodine is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis[1]. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cyanine2 Succinimidyl Ester (iodine). CAS No. 186205-33-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0826.
CY3
Cy3 (Sulfo-Cyanine3) is an orange-fluorescent label for protein and nucleic acid (λex=554, λem=568). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sulfo-Cyanine3. CAS No. 146368-13-0. Pack Sizes: 10 mM * 1 mL in Water; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0822.
Cy3-11-dCTP
Cy3-11-dCTP is a highly acclaimed fluorescent nucleotide derivative extensively utilized in the thriving biomedical industry, emerging as an indispensable instrument for the purpose of effectively and precisely marking DNA or RNA molecules in diverse scientific investigations. Notably, this remarkable compound seamlessly facilitates fluorescent in situ hybridization (FISH) endeavors and empowers meticulous microarray analysis. Grade: ≥ 95%. Mole weight: 1635.
Cy3-11-dUTP
Cy3-11-dUTP is a fluorescent nucleotide used in various molecular biology applications including PCR and in situ hybridization. It is incorporated into DNA during synthesis and enables visualization of the amplified or hybridized product. This reagent is especially useful for identifying structural and functional changes in the genome associated with diseases. Grade: ≥ 95%. Mole weight: 1636.
Cy3-11-UTP
Cy3-11-UTP, an indispensable fluorescent nucleotide analog in the biomedical industry, facilitates research in numerous avenues such as gene expression, protein interactions, and cell signaling pathways through RNA and DNA labeling. Its utility is undeniable in studies linking viral replication and cancer research. Grade: ≥ 95%. Mole weight: 1652.89.
Cy3.5 carboxylic acid
Cy3.5 carboxylic acid. Alternative Names: Cy3.5-carboxylicacidchloride. CAS No. 1144107-79-8. Purity: 95%. Product ID: ACM1144107798-1. Molecular formula: C38H41ClN2O2. Mole weight: 593.2. IUPAC Name: 6-[(2Z)-1,1-dimethyl-2-[(E)-3-(1,1,3-trimethylbenzo[e]indol-3-ium-2-yl)prop-2-enylidene]benzo[e]indol-3-yl]hexanoicacid;chloride. Alfa Chemistry - ISO 9001:32057 Certified.
Cy3B maleimide is a mono-reactive dye containing maleimide group, which can selectively and efficiently attach Cyanine3 fluorophore (an analog of Cy3) to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides). Cy3B is an improved version of Cy3 dyes with significantly increased fluorescence quantum yield and photostability. Uses: Scientific research. Category: Signaling pathways. CAS No. 926905-86-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-172721.
Cy3 dimethyl iodide is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) with a dimethyl group in the iodide salt form. The iodide salt form increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a near-infrared fluorescent dye commonly used in biolabeling and cell imaging. Cy3 dimethyl iodide binds to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples. Uses: Scientific research. Category: Signaling pathways. CAS No. 25470-94-4. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg. Product ID: HY-D1865.
CY3-HOF
CY3-HOF. Alternative Names: Cyanine3-hydrogen-bonded organic framework. Purity: 98%. Product ID: ACMA00064404. Alfa Chemistry - ISO 9001:32057 Certified.
Cy3 maleimide chloride
Cy3 maleimide chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing maleimide functional groups. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The alkyne functional group of Cy3 maleimide chloride can undergo a "thiol-acrylamide" reaction with molecules containing sulfur-oxygen functional groups to form covalent bonds. Cy3 maleimide chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples. Uses: Scientific research. Category: Signaling pathways. CAS No. 1838643-41-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-D1871.
Cy3 NHS ester
Cy3 NHS ester is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis[1]. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Cyanine3 NHS ester. CAS No. 1393363-07-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112498.
Cy3-PEG2-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 2 PEG units. Cy3-PEG2-endo-BCN contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts. Uses: Scientific research. Category: Signaling pathways. CAS No. 1663449-60-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-155327.
CY3-SE
Cy3-SE (Sulfo-Cy3 NHS ester; Sulfo Cyanine3 NHS ester) is a sulfonated cyanine dye-derived fluorescent labeling reagent with λex of about 515 nm and λem of about 568 nm. Cy3-SE can interact with the π-π stacking of biomolecules (e.g., nucleoside monophosphates, proteins), inhibiting the photoisomerization process and increasing the fluorescence quantum yield and lifetime[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sulfo-Cy3 NHS ester; Sulfo Cyanine3 NHS ester. CAS No. 146368-16-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0823.
Cy3-UTP
The resulting assembled mRNA will emit orange fluorescence with the involvement of Cy3-UTPs. Synonyms: Aminoallyl-UTP-Cy3; 5-(3-Aminoallyl)-uridine-5'-triphosphate; Triethylammonium salt; Cyanine 3-AA-UTP; Cyanine 3-Aminoallyluridine-5'-Triphosphate; Cyanine 3-UTP. Grade: >95%. Molecular formula: C43H56N5O22P3S2. Mole weight: 1151.98.
CY3-YNE
CY3-YNE (Sulfo-Cyanine3-alkyne) is a dye for the labeling of soluble proteins, peptides, and oligonucleotides/DNA. CY3-YNE is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sulfo-Cyanine3-alkyne. CAS No. 1010386-62-5. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-D0818.
CY5
CY5 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis[1]. CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Sulfo-Cyanine5. CAS No. 146368-11-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D0821.
Cy5-11-dCTP
Cy5-11-dCTP, a modified nucleotide employed in biomedical research to detect and label DNA, proves useful in a range of molecular biology applications. Its fluorescent properties enable incorporation into DNA via PCR, suitable for real-time PCR and microarray analysis. Whether for high-throughput DNA sequencing or gene expression and genotyping studies, its brightness and stability are unmatched. Beyond research, Cy5-11-dCTP has been effective in diagnosing and treating numerous diseases, including cancer and infectious agents. Grade: ≥ 95%. Mole weight: 1661.