A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Eplerenone EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2'R,4aS,4bR,5aR,6aS,9aS,9bR,10R)-4a,6a-dimethyl-2,5'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylic acid. CAS No. 209253-82-7. Molecular Formula: C23H28O6. Mole Weight: 400.46. Catalog: APB209253827.
Eplerenone EP Impurity E
An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: 7β-Eplerenone; (7β,11α,17α)-9,11-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid γ-Lactone Methyl Ester. Grades: > 95%. CAS No. 209253-81-6. Molecular formula: C24H30O6. Mole weight: 414.50.
Eplerenone EP Impurity E
Eplerenone EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2'R,4aS,4bR,5aR,6aS,9aS,9bR,10S)-methyl 4a,6a-dimethyl-2,5'-dioxo-3,4,4a,4',5a,5',6,6a,8,9,9a,9b,10,11-tetradecahydro-2H,3'H-spiro[cyclopenta[1,2]phenanthro[4,4a-b]oxirene-7,2'-furan]-10-carboxylate. CAS No. 209253-81-6. Molecular Formula: C24H30O6. Mole Weight: 414.49. Catalog: APB209253816.
Eplerenone EP Impurity F
Eplerenone EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-((4aS, 4bR, 5aR, 6aS, 7R, 9aS, 9bR, 10R)-7-hydroxy-10-(methoxycarbonyl)-4a, 6a-dimethyl-2-oxo-2, 3, 4, 4a, 5a, 6, 6a, 7, 8, 9, 9a, 9b, 10, 11-tetradecahydrocyclopenta[1, 2]phenanthro[4, 4a-b]oxiren-7-yl)propanoic acid. CAS No. 579484-30-3. Molecular Formula: C24H32O7. Mole Weight: 432.51. Catalog: APB579484303.
Eplerenone EP Impurity F Potassium Salt
An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: (7α,11α,17α)-9,11-Epoxy-17-hydroxy-3-oxopregn-4-ene-7,21-dicarboxylic Acid; 7-Methyl Ester Monopotassium Salt; SC 70303; Eplerenone EP Impurity F Potassium Salt. Grades: > 95%. CAS No. 95716-98-6. Molecular formula: C24H31O7K. Mole weight: 470.6.
Eplerenone EP Impurity G
An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: Mexrenone; Spiro[17H-cyclopenta[a]phenanthrene-17,2'(5'H)-furan], pregn-4-ene-7,21-dicarboxylic acid deriv.; 17-Hydroxy-3-oxo-17α-pregn-4-ene-7α,21-dicarboxylic acid methyl ester γ-lactone. Grades: > 95%. CAS No. 41020-65-9. Molecular formula: C24H32O5. Mole weight: 400.52.
Eplerenone EP Impurity G
Eplerenone EP Impurity G. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2'R,7R,8R,9S,10R,13S,14S)-methyl 10, 13-dimethyl-3, 5'-dioxo-1, 2, 3, 4', 5', 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17, 2'-furan]-7-carboxylate. CAS No. 41020-65-9. Molecular Formula: C24H32O5. Mole Weight: 400.51. Catalog: APB41020659.
Eplerenone hydroxyacid potassium salt
Eplerenone hydroxyacid potassium salt. Group: Biochemicals. Alternative Names: (7a,11a,17a)-9,11-Epoxy-17-hydroxy-3-oxopregn-4-ene-7,21-dicarboxylic acid; 7-Methyl ester monopotassium salt; SC 70303. Grades: Highly Purified. CAS No. 95716-98-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C24H31KO7. US Biological Life Sciences.
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Eplerenone impurity 1
Eplerenone impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 95716-98-6. Molecular Formula: C24H31KO7. Mole Weight: 470.6. Catalog: APB95716986.
Eplerenone Impurity 1
An impurity of Eplerenone. Eplerenone is a potassium-sparing diuretic that selectively blocks aldosterone activation of the mineralcorticoid receptor, demonstrating little activity towards other steroid receptors. Synonyms: (2'R,7S,10R,11R,13S,14S)-methyl 11-hydroxy-10, 13-dimethyl-3, 5'-dioxo-1, 2, 3, 4', 5', 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16-hexadecahydro-3'H-spiro[cyclopenta[a]phenanthrene-17, 2'-furan]-7-carboxylate. Grades: > 95%. Molecular formula: C24H32O6. Mole weight: 416.52.
Eplivanserin hemifumarate
Eplivanserin hemifumarate is a potent and selective 5-HT2A antagonist (IC50 = 5.8 and 120 and >100 nM for 5-HT2A, 5-HT2B and 5-HT2C, respectively) with no activity for dopamine, histamine and adrenergic receptors. It attenuates cocaine-induced hyperactivity, increases dopamine (DA) release in rat medial prefrontal cortex (mPFC) and potentiates haloperidol-induced DA release in the mPFC and nucleus accumbens. Synonyms: SR-46349B; SR 46349B; SR46349B; (1Z,2E)-1-(2-Fluorophenyl)-3-(4-hydroxyphenyl)-2-propen-1-one O-[2-(dimethylamino)ethyl]oxime hemifumarate. Grades: ≥98% by HPLC. CAS No. 130580-02-8. Molecular formula: C19H21FN2O2.1/2C4H4O4. Mole weight: 386.42.
Eplivanserin hemifumarate
Eplivanserin hemifumarate. Group: Biochemicals. Grades: Purified. CAS No. 130580-02-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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Epmedin B
Cas No. 110623-73-9.
Epmedin C
Cas No. 110642-44-9.
Epo
Epo. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ERYTHROPOIETIN RAT;EPO;erythropoietin from human urine*approx 100 units;Erythropoietin,from human urine;ERYTHROPOIETIN HUMAN, RECOMB. FROM CHO- CELLS, PGE W. 10 U;ERYTHROPOIETIN FROM HUMAN URINE*APPROX 5 00 UNITS PE;ERYTHROPOIETIN FROM HUMAN URINE*APPROX 100 UNITS PER;Erythropietin human. Product Category: Heterocyclic Organic Compound. Appearance: lyophilized powder. CAS No. 11096-26-7. Molecular formula: NULL. Mole weight: 0. Product ID: ACM11096267. Alfa Chemistry ISO 9001:2015 Certified.
Epobis
Epobis is a nonerythropoietic and neuroprotective agonist of the erythropoietin receptor with anti-Inflammatory and memory enhancing effects. Grades: 98%.
Epoetin beta
Epoetin beta (rhEPO) is a recombinant form of erythropoietin. Epoetin beta is responsible for the maintenance of erythropoiesis and can be used for anaemia research [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: rhEPO; EPOCH; Genetical recombination. CAS No. 122312-54-3. Pack Sizes: 500 U; 1000 U; 2000 U; 5000 U. Product ID: HY-114134.
Epoformin
Epoformin is an antibiotic produced by Penicillum claviforme. It has only weak antibacterial activity, but it has a strong effect on PS cells and a poor effect on sarcoma L-1210. Synonyms: Antibiotic 417-A. CAS No. 52146-62-0. Molecular formula: C7H8O3. Mole weight: 140.14.
Epon 828, Technical Grade
EPON 828 is an undiluted clear difunctional bisphenol A/epichlorohydrin derived liquid epoxy resin. Group: Biochemicals. Grades: Purified. CAS No. 25068-38-6. Pack Sizes: 10g, 25g. Molecular Formula: xC18H21ClO3. US Biological Life Sciences.
Worldwide
Eponemycin
Eponemycin is an antibiotic against B16 melanoma produced by Streptornyces hygroscopicus No. P247-71. The in vivo test has good curative effect on B16 melanoma and moderate curative effect on L1210 leukemia, but the survival period of mice bearing P388 leukemia is not significantly prolonged. Synonyms: Antibiotic BU 3862T; 1,2-Epoxy-2-hydroxymethyl-4-(N-isooctanoylserylamino)-6-methylhept-6-ene-3-one. CAS No. 126509-46-4. Molecular formula: C20H34N2O6. Mole weight: 398.49.
Epopromycin A
Epopromycin A is an antibiotic produced by Streptornyces sp. NK04000. It has inhibitory effect on plant protoplast cell wall synthesis. CAS No. 153540-55-7. Molecular formula: C21H36N2O6. Mole weight: 412.52.
Epopromycin B
Epopromycin B is an antibiotic produced by Streptornyces sp. NK04000. It has inhibitory effect on plant protoplast cell wall synthesis. Synonyms: (+)-Epopromycin B. CAS No. 153540-56-8. Molecular formula: C21H38N2O6. Mole weight: 414.53.
Epoprostenol
Epoprostenol. Group: Biochemicals. Grades: Purified. CAS No. 61849-14-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Epoprostenol sodium
Epoprostenol sodium (Prostaglandin I2) sodium salt, the synthetic form of the natural prostaglandin derivative prostacyclin (prostaglandin I2), is registered worldwide for the treatment of Pulmonary arterial hypertension (PAH). Epoprostenol sodium is used in pulmonary hypertension and transplantation as a potent inhibitor of platelet aggregation [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Prostaglandin I2 sodium salt; Prostacyclin sodium salt; Flolan. CAS No. 61849-14-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0126A.
Epoprostenol Sodium
Epoprostenol Sodium is the sodium salt form of epoprostenol, which is a synthetic prostacyclin. It has vasodilatory and anticoagulant activity. It is a short-lived product of the cyclooxygenase pathway in vascular endothelial cells. It prevents the formation of platelet plugs and is an effective vasodilator. It is a potent inhibitor of platelet aggregation by antagonizing thromboxane A2 and stimulating platelet adenylyl cyclase. It directly simulates prostaglandin receptors in arterial vascular smooth muscle, thereby causing vasodilatation. lt is also used for the treatment of pulmonary hypertension. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue. It is vasoprotective, protecting arterial walls from injury-induced lesions and cytoprotective in the liver and gastrointestinal tract. It was developed by GlaxoSmithKline and has been listed. Uses: Epoprostenol sodium has vasodilatory and anticoagulant activity. it prevents the formation of platelet plugs and is an effective vasodilator. lt is also used for the treatment of pulmonary hypertension. Synonyms: Prostacyclin Sodium Salt; (5Z,9α,11α,13E,15S)-6,9-epoxy-11,15-Dihydroxy-prosta-5,13-dien-1-oic Acid Sodium Salt; Flolan. Grades: >99 %. CAS No. 61849-14-7. Molecular formula: C20H31O5Na. Mole weight: 374.45.
Epostane
3 β-Hydroxysteroid dehydrogenase inhibitor; a derivative of trilostane. Interceptive. Group: Biochemicals. Alternative Names: (4α,5α,17 β)-4,5-Epoxy-3,17-dihydroxy-4,17-dimethylandrost-2-ene-2-carbonitrile; Win 32729. Grades: Highly Purified. CAS No. 80471-63-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Epostane
Epostane. Uses: Designed for use in research and industrial production. Additional or Alternative Names: EPOSTANE;(4α,5α,17β)-4,5-Epoxy-3,17-dihydroxy-4,17-dimethylandrost-2-ene-2-carbonitrile;Win-32729;4α,5-Epoxy-3,17β-dihydroxy-4,17-dimethyl-5α-androst-2-ene-2-carbonitrile;Epostan. Product Category: Heterocyclic Organic Compound. CAS No. 80471-63-2. Molecular formula: C22H31NO3. Mole weight: 357.491. Product ID: ACM80471632. Alfa Chemistry ISO 9001:2015 Certified.
Epostatin
Epostatin is a dipeptidase II inhibitor produced by Streptomyces sp. MJ 995-OF5. It can inhibit DPP-II with an IC50 of 9.6 μg/mL, and has a weak inhibitory effect on other dipeptidase peptidases. Synonyms: L-Glutamine, N(sup 2)- (4- (2-hexyl-2, 3, 4, 4a-tetrahydrocyclopent (b)oxireno (c)pyridin-7 (1aH)-ylidene)-1-oxo-2-butenyl)-. Grades: >98%. CAS No. 181372-99-6. Molecular formula: C23H33N3O5. Mole weight: 431.52.
Epothilon A
Epothilons A is a 16-membered macrolide antibiotic produced by the myxobacterium Sorangium cellulosum. It has strong cytotoxicity and has the effect of resisting plant pathogenic fungi. Uses: Antineoplastic agents. Synonyms: (-)-Epothilone A; Epo A; NSC-684362; (1R,5S,6S,7R,10S,14S,16S)-6,10-dihydroxy-5,7,9,9-tetramethyl-14-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-13,17-dioxabicyclo[14.1.0]heptadecane-8,12-dione. Grades: >98%. CAS No. 152044-53-6. Molecular formula: C26H39NO6S. Mole weight: 493.65.
Epothilon B
Epothilons B is a 16-membered macrolide antibiotic produced by the myxobacterium Sorangium cellulosum, which is used as a microtubule stabilization agent (EC0.01 = 1.8 μM). It has strong cytotoxicity and has the effect of resisting plant pathogenic fungi. Uses: Antineoplastic agents. Synonyms: Patupilone; (-)-Epothilone B. Grades: >98%. CAS No. 152044-54-7. Molecular formula: C27H41NO6S. Mole weight: 507.68.
Epothilone
Epothilone. Uses: For analytical and research use. Group: Impurity standards. CAS No. 189453-10-9. Molecular Formula: C27H41NO5S. Mole Weight: 491.69. Catalog: APB189453109.
Epothilone A
Epothilone A. CAS No. 152044-53-6. Product ID: 8-04666. Molecular formula: C26H39NO6S. Mole weight: 493.66.
Epothilone A
Epothilone A is a microtubule inhibitor isolated from the myxobacteria, Sorangium cellulosum. Epothilone A acts by stabilising microtubule formation at the taxol binding site and causes cell cycle arrest at the G2/M transition, leading to cytotoxicity. Epothilone A is under investigation as an antitumor agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 152044-53-6. Pack Sizes: 100ug. US Biological Life Sciences.
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Epothilone A
Epothilone A is a competitive inhibitor of the binding of [ 3 H] paclitaxel to tubulin polymers, with a K i of 0.6-1.4 μM. Uses: Scientific research. Group: Natural products. Alternative Names: Epo A. CAS No. 152044-53-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13503.
Epothilone B
Epothilone B is a microtubule inhibitor isolated from the myxobacteria, Sorangium cellulosum. Like epothilone A, epothilone B acts by stabilising microtubule formation at the taxol binding site and causes cell cycle arrest at the G2/M transition, leading to cytotoxicity. Group: Biochemicals. Grades: Highly Purified. CAS No. 152044-54-7. Pack Sizes: 100ug. US Biological Life Sciences.
Epothilone B. CAS No. 152044-54-7. Product ID: 8-04667. Molecular formula: C27H41NO6S. Mole weight: 507.68.
Epothilone B
Epothilone B is a microtubule stabilizer with a K i of 0.71μM. It acts by binding to the αβ-tubulin heterodimer subunit which causes decreasing of αβ-tubulin dissociation. Uses: Scientific research. Group: Signaling pathways. Alternative Names: EPO 906; Patupilone. CAS No. 152044-54-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-17029.
Epothilone B (synthetic)
Epothilone B (synthetic). Group: Biochemicals. Alternative Names: (1S, 3S, 7S, 10R, 11S, 12S, 16R)-7, 11-Dihydroxy-8, 8, 10, 12, 16-pentamethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-4, 17-dioxabicyclo[14. 1. 0]heptadecane-5, 9-dione; (-)-Epothilone B; EPO 906. Grades: Highly Purified. CAS No. 152044-54-7. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C27H41NO6S. US Biological Life Sciences.
Worldwide
Epothilone B (synthetic) (EpoB)
Epothilones are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel-resistant tumors. Epothilone B is what is known as a microtubule stabilizer. When a cell divides, the chromosomes that will end up in each cell are separated by thin filaments called microtubules. Normally these microtubules then break down as the cell division progresses. This class of cytotoxic chemo drugs prevents that break down and thus prevents cells from completing division. Group: Biochemicals. Alternative Names: EpoB. Grades: Highly Purified. CAS No. 52044-54-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Epothilone C
Epothilone C. CAS No. 186692-73-9. Product ID: 8-04670. Molecular formula: C26H39NO5S. Mole weight: 477.66.
Epothilone C
Epothilone C is a novel microtubule inhibitor and acts as an antineoplastic agent. Epothilones are originally isolated from cellulose-degrading myxobacterium Sorangium cellulosum. Synonyms: (-)-Deoxyepothilone A; (-)-Desoxyepothilone A; Desoxyepothilone A. CAS No. 186692-73-9. Molecular formula: C26H39NO5S. Mole weight: 477.66.
Epothilone D
Epothilone D (KOS 862) is a potent microtubule stabilizer. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KOS 862. CAS No. 189453-10-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15278.
Epothilone D. CAS No. 189453-10-9. Product ID: 8-04671. Molecular formula: C27H41NO5S. Mole weight: 491.68.
Epothilone D (synthetic)
Epothilone D (synthetic). Group: Biochemicals. Alternative Names: (4S, 7R, 8S, 9S, 13Z, 16S) -4, 8-Dihydroxy-5, 5, 7, 9, 13-pentamethyl-16- [ (1E) -1-methyl-2- (2-methyl-4-thiazolyl) ethenyl] oxacyclohexadec-13-ene-2, 6-dione; (-)-Desoxyepothilone B; (-)-Epothilone D. Grades: Highly Purified. CAS No. 189453-10-9. Pack Sizes: 1mg. Molecular Formula: C27H41NO5S. US Biological Life Sciences.
Worldwide
Epothilone D (synthetic) (12,13-Deoxyepothilone B, EpoA)
Epothilones are polyketid. Group: Biochemicals. Alternative Names: 12,13-Deoxyepothilone B, EpoA. Grades: Highly Purified. Pack Sizes: 100ug. US Biological Life Sciences.
specific inhibitor of aminopeptidase B and leucine aminopeptidase. Product ID: 8-04673. Molecular formula: C27H41NO7S. Mole weight: 523.68.
Epothilone F
Epothilone F, an active metabolite of Epothilone D, prevents cancer cells from dividing by interfering with tubulin. Synonyms: (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-3-[(E)-1-[2-(hydroxymethyl)-1,3-thiazol-4-yl]prop-1-en-2-yl]-8,8,10,12,16-pentamethyl-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione; epothilone F. Grades: >98%. CAS No. 208518-52-9. Molecular formula: C27H41NO7S. Mole weight: 523.69.
Epoxiconazole is a fungicide used to control a wide range of fungal diseases. Synonyms: 1H-1,2,4-Triazole, 1-[[(2R,3S)-3-(2-chlorophenyl)-2-(4-fluorophenyl)-2-oxiranyl]methyl]-, rel-; 1H-1,2,4-Triazole, 1-[[(2R,3S)-3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiranyl]methyl]-, rel-; 1H-1,2,4-Triazole, 1-[[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiranyl]methyl]-, cis-(±)-; rel-1-[[(2R,3S)-3-(2-Chlorophenyl)-2-(4-fluorophenyl)-2-oxiranyl]methyl]-1H-1,2,4-triazole; BAS 480F; Fuhuanzuo; Opal; Opal (fungicide); Opus; Rubric. Grades: ≥95%. CAS No. 133855-98-8. Molecular formula: C17H13ClFN3O. Mole weight: 329.76.
Epoxiconazole
Epoxiconazole, a fungicide, is a demethylation inhibitor of the Ergosterol biosynthesis pathway. Epoxiconazole exhibits strong inhibitory effects on both carbendazim-resistant and phenamacril-resistant isolates, and can be used for controlling many crop diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 133855-98-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119683.
Chemical Class. Uses: For analytical and research use. Group: Reagents. Grades: analytical standard. CAS No. 8016-11-3. Pack Sizes: 500MG, 2.5G.
Epoxidized soybean oil
Epoxidized soybean oil. Synonyms: ESBO, Soybean oil, epoxidized. CAS No. 8013-7-8. Pack Sizes: 1 kg. Product ID: CDC10-0292. Molecular formula: C57H98O12. Category: Cosmetic Plasticizers. Product Keywords: Cosmetic Ingredients; Cosmetic Plasticizers; Epoxidized soybean oil; CDC10-0292; 8013-07-8; C57H98O12; ESBO, Soybean oil, epoxidized; 232-391-0; MFCD00163560; 8013-07-8. Grade: analytical standard. Purity: 0.9999. Color: Colourless Thick. EC Number: 232-391-0. Physical State: Oil. Quality Level: 100. Application: Refer to the product's Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. Boiling Point: >150°C. Melting Point: N/A. Density: 0.994 g/cm3. Product Description: Epoxidized soya bean oil may be used as a reference standard for the accurate detection of regulated dyes. These dyes, although banned in many countries, are still being used illicitly as additives in food products.
Epoxidized Soybean Oil
Epoxidized Soybean Oil. Uses: Designed for use in research and industrial production. CAS No. 8013-7-8. Product ID: ACM8013078. Alfa Chemistry ISO 9001:2015 Certified.
Epoxidized Soybean Oil
Epoxidized Soybean Oil. We stock inventory in warehouses throughout the United States, allowing us to serve customers in all regions in a timely and cost effective manner.
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Epoxomicin
Epoxomicin is a naturally occurring selective proteasome inhibitor with anti-inflammatory activity. Uses: Proteasome inhibitors. Synonyms: BU-4061T. Grades: >98%. CAS No. 134381-21-8. Molecular formula: C28H50N4O7. Mole weight: 554.72.
Epoxomicin
Epoxomicin (BU-4061T) is an epoxyketone-containing natural product and a potent, selective and irreversible proteasome inhibitor. Epoxomicin covalently binds to the LMP7, X, MECL1, and Z catalytic subunits of the proteasome and potently inhibits primarily the chymotrypsin-like activity. Epoxomicin can cross the blood-brain barrier. Epoxomicin has strongly antitumor and anti-inflammatory activity [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. Alternative Names: BU-4061T. CAS No. 134381-21-8. Pack Sizes: 10 mM * 1 mL; 100 μg; 1 mg; 5 mg; 10 mg; 20 mg. Product ID: HY-13821.
Epoxomicin
Antibiotic. Potent anticancer compound. Cell permeable, potent, selective and irreversible 20S proteasome inhibitor. Predominantly inhibits the chymotrypsin-like (CTRL) activity of the proteasome. Exhibits lower level inhibition of proteasome trypsin-like and caspase-like activitives (100 and 1,000-fold slower rates respectively). Anti-inflammatory. Antimicrobial and antimalarial. Anti-parasitic. Stimulates bone formation by inhibiting osteoblast proteasome activity. Induces Parkinson's-like symptoms in rats. The ubiquitin-proteasome system (UPS) and autophagy serve as two complementary, reciprocally regulated protein degradation systems. Blockade of UPS by Epoxomicin activates autophagy. Group: Biochemicals. Alternative Names: N-acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N- [ (1S) -3-methyl-1- [ [ (2R) -2-methyloxiranyl] carbonyl] butyl] -L-threoninamide, BU 4061T. Grades: Highly Purified. CAS No. 134381-21-8. Pack Sizes: 50ug, 100ug, 250ug, 500ug. Molecular Formula: C??H??N?O?, Molecular Weight: 554.7. US Biological Life Sciences.
Originally isolated from Actinomycetes strain based on its potent in vivo antitumor activity, Epoxomicin is a potent, cell-permeable, selective and irreversible proteasome inhibitor. More potent inhibitor of the chymotrypsin-like activity of the proteasome than Lactacystin. Blocks also trypsin-like and PGPH activities of the proteasome. Group: Biochemicals. Grades: Highly Purified. CAS No. 134381-21-8. Pack Sizes: 50ug, 250ug. US Biological Life Sciences.