A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Equilin is one of the estrogens present in the mixture of estrogens isolated from horse urine and marketed as Premarin. Uses: An estrogen. Alternative Names: 3-Hydroxy-13-methyl-9,11,12,14,15,16-hexahydro-6H-cylcopenta(a)phenanthren-17-one. Grades: > 95%. CAS No. 474-86-2. Molecular formula: C18H20O2. Mole weight: 268.36.
Equilin
An estrogen found in Premarin, which is a mixture of conjugated estrogens widely used in hormone replacement therapy. Group: Biochemicals. Alternative Names: 1,3,5,7-Estratetraen-3-ol-17-one; 3-Hydroxyestra-1,3,5(10),7-tetraen-17-one; 7-Dehydroestrone; NSC 10971. Grades: Highly Purified. CAS No. 474-86-2. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Equilin 3-Benzoate
Estrogen derivative. Displays inhibiton activity towards pig liver steroid Δ4-5 β-reductase. Group: Biochemicals. Alternative Names: 3-(Benzoyloxy)-estra-1,3,5(10),7-tetraen-17-one; 3-Hydroxy-estra-1,3,5(10),7-tetraen-17-one Benzoate. Grades: Highly Purified. CAS No. 6030-80-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Equilin 3-Sulfate-d4 Sodium Salt (stabilized with Tris, 50% w/w)
A labeled metabolite of Equilin. Group: Biochemicals. Alternative Names: 3-(Sulfooxy)estra-1,3,5(10),7-tetraen-17-one-d4 Sodium Salt; t; 3-Hydroxyestra-1,3,5(10),7-tetraen-17-one-d4 Hydrogen Sulfate Sodium Salt; Sodium Equilin-d4 3-Monosulfate; Sodium Equilin-d4 Sulfate. Grades: Highly Purified. CAS No. 285979-81-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Equilin 3-sulfate sodium salt
Equilin 3-sulfate sodium salt. Group: Biochemicals. Alternative Names: 3-(Sulfooxy)estra-1,3,5(10),7-tetraen-17-one sodium salt; 3-Hydroxyestra-1,3,5(10),7-tetraen-17-one hydrogen sulfate sodium salt; Sodium equilin 3-monosulfate. Grades: Highly Purified. CAS No. 16680-47-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C18H19NaO5S. US Biological Life Sciences.
Worldwide
Equilin 3-Sulfate Sodium Salt
A derivative of Equilin. Equilin is one of the estrogens present in the mixture of estrogens isolated from horse urine and marketed as Premarin. Uses: Estrogens. Alternative Names: 3-(Sulfooxy)estra-1,3,5(10),7-tetraen-17-one Sodium Salt; 3-Hydroxyestra-1,3,5(10),7-tetraen-17-one Hydrogen Sulfate Sodium Salt; Sodium Equilin 3-Monosulfate. Grades: > 95%. CAS No. 16680-47-0. Molecular formula: C18H19O5S. Na. Mole weight: 370.4.
Equilin 3-Sulfate Sodium Salt (Stabilized with Tris, 50% w/w)
Metabolite of Equilin. Equilin 3-Sulfate Sodium Salt (Stabilized with TRIS, 50% w/w). Group: Biochemicals. Alternative Names: 3-(Sulfooxy)estra-1,3,5(10),7-tetraen-17-one Sodium Salt; 3-Hydroxyestra-1,3,5(10),7-tetraen-17-one Hydrogen Sulfate Sodium Salt; Sodium Equilin 3-Monosulfate; Sodium Equilin Sulfate. Grades: Highly Purified. CAS No. 16680-47-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Equilin-d4
Labeled Equilin. An estrogen found in Premarin, which is a mixture of conjugated estrogens widely used in hormone replacement therapy. Group: Biochemicals. Alternative Names: 1,3,5,7-Estratetraen-3-ol-17-one-d4; 3-Hydroxyestra-1,3,5(10),7-tetraen-17-one-d4; 7-Dehydroestrone-d4; NSC 10971-d4. Grades: Highly Purified. CAS No. 285979-79-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
equine arterivirus serine peptidase
In the equine arterivirus (EAV), the replicase gene is translated into open reading frame 1a (ORF1a) and ORF1ab polyproteins. This enzyme is the main viral proteinase and processes five cleavage sites in the ORF1a protein and three in the ORF1b-encoded part of the ORF1ab protein to yield nonstructural proteins (nsp5-nsp12). It combines the catalytic system of a chymotrypsin-like serine peptidase (His-Asp-Ser catalytic triad) with the substrate specificity of a 3C-like serine peptidase (Glu or Gln) at the P1 position and a small amino-acid residue (Gly, Ser or Ala) at the P1' position. Cleavage of ORF1ab by this enzyme is essential for viral replication. Belongs in peptidase family S32. Group: Enzymes. Enzyme Commission Number: EC 3.4.21.114. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4109; equine arterivirus serine peptidase; EC 3.4.21.114. Cat No: EXWM-4109.
Equisetin
The tetramic acid equisetin, is produced by a number of species of Fusarium. Interest in equisetin emerged with reports of its inhibitory activity against human immunodeficiency virus type 1 (HIV-1) integrase in vitro that was mechanistically distinct from previously described inhibitors. Equisetin inhibits 3' end-processing and strand transfer as well as disintegration catalysed by either the full-length enzyme or the truncated integrase core. Group: Biochemicals. Grades: Highly Purified. CAS No. 57749-43-6. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Equisetin
Equisetin is an N-methylserine-derived acyl tetramic acid, quorum sensing inhibitor (QSI), herbicides and antibiotics. Equisetin specifically inhibits the anionic carriers of substrates in the inner mitochondrial membrane. Equisetin inhibits the activity of HIV-1 integrase, 11β-HSD1, and 2,4-dinitrophenol (Dnp)-stimulated ATPase (IC50 = ~8 nmol per mg of protein). Equisetin exhibits growth inhibition of bacteria, anti-inflammatory, amelioration of lipid-associated disorders, and cytotoxic effects[1][2][3][4][5][6][7][8][9][10][11]. Uses: Scientific research. Category: Signaling pathways. CAS No. 57749-43-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N6711.
Equisetin
Equisetin is an antibiotic produced by Fusarium equiseti NRRL 5537. Activity against gram-positive bacteria. Alternative Names: (-)-Equisetin. Grades: >98%. CAS No. 57749-43-6. Molecular formula: C22H31NO4. Mole weight: 373.48.
ER-000444793
ER-000444793 is a potent inhibitor of mitochondrial permeability transition pore (mPTP) opening. ER-000444793 inhibits mPTP with an IC50 of 2.8 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 792957-74-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100852.
ER-076349
ER-076349 (Eribulin intermediate) is an inhibitor of tubulin polymerization, induces G2-M cell cycle arrest, and disrupts mitotic spindles. ER-076349 inhibits cancer cell growth, and inhibits tumor growth in several human tumor xenografts. ER-076349 is an analog of Halichondrin B[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Eribulin intermediate. CAS No. 253128-15-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-42484.
ER 27319 maleate
ER 27319 maleate. Group: Biochemicals. Grades: Purified. CAS No. 1204480-26-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
ER 50891
ER 50891. Group: Biochemicals. Grades: Purified. CAS No. 187400-85-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
ER-878898
Gemcitabine intermediate. Uses: Gemcitabine intermediate. Alternative Names: 2-Deoxy-2,2-difluoro-D-erythro-pentofuranose-3,5-dibenzoate 1-Methanesulfonate. Grades: 97%. CAS No. 122111-11-9. Molecular formula: C20H18F2O8S. Mole weight: 456.41.
Erabulenol A
Erabulenol A is a cholesteryl ester transfer protein (CETP) inhibitor produced by Penicillum sp. FO-5637. Alternative Names: Deoxyherqueinone; Atrovenetin monomethyl ether. CAS No. 20887-73-4. Molecular formula: C20H20O6. Mole weight: 356.37.
Erabulenol B
Erabulenol B is a cholesteryl ester transfer protein (CETP) inhibitor produced by Penicillum sp. FO-5637. Molecular formula: C30H30O10. Mole weight: 550.55.
Eragidomide
Eragidomide (CC-90009) is a first-in-class GSPT1-selective cereblon (CRBN) E3 ligase modulator, acts as a molecular glue. Eragidomide coopts the CRL4CRBN to selectively target GSPT1 for ubiquitination and proteasomal degradation[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CC-90009. CAS No. 1860875-51-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-130800.
ERAS-0015(JYP0015) is a tricomplex inhibitor of panRAS(ON) targeting of active RAS, it binds to Cyclophilin A (CYPA) to form a high-affinity complex that sterically occludes RAS-effector interactions. It exhibits potential for research in RAS-mutant solid tumors. Group: Inhibitors. Alternative Names: JYP0015. CAS No. 3034673-92-9. Pack Sizes: 1mg. Product ID: E5848. Formula: C46H60N8O5S.
United States; Europe
Eras-4001
Eras-4001 (Compound 14-1) is a pan-KRAS inhibitor. Eras-4001 has potent antitumor activities and significantly inhibits the proliferation of wild-type and mutant (such as KRASG12D, KRASG12V and KRASG12C) cancer cells. Eras-4001 effectively inhibits tumor growth in GP2D and Panc0403 xenograft mouse models[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3024878-19-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-175870.
Erasin
Erasin is a potent Erlotinib (HY-50896)-resistance antagonizing STAT3 inhibitor with IC50s of 9.7 and 24 μM against STAT3 and STAT1, respectively. Erasin induces cancer cells apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2256056-21-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-115594.
Erastin
Erastin is an antitumor agent selective for tumor cells bearing oncogenic RAS (i.e. HRAS, KRAS). Erastin produces non-apoptotic tumor cell death by altering mitochondrial voltage-dependent anion channel (VDAC) gating allowing cations to enter mitochondria and leading to release of oxidative species causing oxidative cell death. Erastin blocks and reverses mitochondrial depolarization after microtubule destabilizers in intact cells and antagonized tubulin-induced VDAC blockage in planar bilayers. Reversal of tubulin-VDAC interaction by erastin antagonizes Warburg metabolism and restores oxidative mitochondrial metabolism. Alternative Names: Erastin. Grades: 0.98. CAS No. 571203-78-6. Molecular formula: C30H31ClN4O4. Mole weight: 547.04454.
Erastin
Erastin is a ferroptosis inducer. Erastin exhibits the mechanism of ferroptosis induction related to ROS and iron-dependent signaling. Erastin inhibits voltage-dependent anion channels (VDAC2/VDAC3) and accelerates oxidation, leading to the accumulation of endogenous reactive oxygen species. Erastin also disrupts mitochondrial permeability transition pore (mPTP) with anti-tumor activity. Furthermore, Erastin can block the uptake of cystine mediated by SLC7A11 and also spares UMRC6-EV and -C91A cells from disulfidptosis under glucose starvation[1][2][3][4][5][6][7][8][9][10][11][12][13][14]. Uses: Scientific research. Category: Signaling pathways. CAS No. 571203-78-6. Pack Sizes: 1 mg; 1 mg * 5; 1 mg * 10. Product ID: HY-15763.
Erastin is a selective antitumor agent that displays greater lethality in human tumor cells harboring mutations in the oncogenes HRAS, KRAS or BRAF. It binds to mitochondrial volatage-dependent anion channels (VDAC) proteins, more specifically on VDAC2 and alters its gating. Erastin rapidly induces an oxidative, non-apoptotic cell death in several human tumors harboring activating mutations in the RAS-RAF-MEK signaling. Group: Biochemicals. Alternative Names: 2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-Quinazolinone. Grades: Highly Purified. CAS No. 571203-78-6. Pack Sizes: 1mg. Molecular Formula: C??H??ClN?O?, Molecular Weight: 547.04. US Biological Life Sciences.
Worldwide
Erastin
Erastin is a ferroptosis activator by acting on mitochondrial VDAC, exhibiting selectivity for tumor cells bearing oncogenic RAS. Solutions are unstable and should be fresh-prepared. Group: Inhibitors. CAS No. 571203-78-6. Pack Sizes: 5mg. Product ID: S7242. Formula: C30H31ClN4O4. Smiles: CCOC1=CC=CC=C1N2C(=O)C3=CC=CC=C3N=C2C(C)N4CCN(CC4)C(=O)COC5=CC=C(C=C5)Cl.
United States; Europe
Erastin2
Erastin2, an Erastin (HY-15763) analog, is a ferroptosis inducer and a potent, selective inhibitor of the system xc(-) cystine/glutamate transporter[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1695533-44-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139087.
Erastin impurity 2
Erastin impurity 2. Uses: For analytical and research use. Molecular formula: C16H22N4O2. Mole weight: 302.38. Catalog: APB11220.
Erastin impurity 4
Erastin impurity 4. Uses: For analytical and research use. CAS No. 361382-26-5. Molecular formula: C16H23NO2. Mole weight: 261.37. Catalog: APB361382265.
Erastin impurity 5
Erastin impurity 5. Uses: For analytical and research use. CAS No. 1181267-30-0. Molecular formula: C20H24O5S. Mole weight: 376.47. Catalog: APB1181267300.
Eravacycline
Eravacycline (TP-434) is a potent and broad-spectrum antibacterial agent. Category: Active pharmaceutical ingredients. CAS No. 1207283-85-9. Product ID: API1207283859. Molecular formula: C27H31FN4O8. Mole weight: 558.56.
Eravacycline
Eravacycline, also known as TP-434, a novel antibiotic. Eravacycline showed potent broad-spectrum activity against 90% of the isolates (MIC90) in each panel at concentrations ranging from 0.008 to 2 μg/ml for all species panels except those of Pseudomonas aeruginosa and Burkholderia cenocepacia (MIC90 values of 32 μg/ml for both organisms). Alternative Names: TP-434; TP 434; TP434. Grades: 98%. CAS No. 1207283-85-9. Molecular formula: C27H31FN4O8. Mole weight: 558.56.
Eravacycline dihydrochloride
Eravacycline, a novel fluorocycline previously known as TP-434, in virto has broad-spectrum activity against both Gram-positive and Gram-negative aerobic and anaerobic pathogens including important antimicrobial resistant pathogens such as methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), and extended-spectrum ?-lactamase (ESBL)-producing and carbapenemaseproducing Enterobacteriaceae and multidrug-resistant Acinetobacter baumannii. Alternative Names: (4S,4aS,5aR,12aR)-4-(dimethylamino)-7-fluoro-1,10,11,12a-tetrahydroxy-3,12-dioxo-9-[(2-pyrrolidin-1-ylacetyl)amino]-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;dihydrochloride; Eravacycline (dihydrochloride). CAS No. 1334714-66-7. Molecular formula: C27H33Cl2FN4O8. Mole weight: 631.48.
Eravacycline dihydrochloride
Eravacycline dihydrochloride (TP-434 dihydrochloride) is a potent and broad-spectrum antibacterial agent. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TP-434 dihydrochloride; TP-434-046. CAS No. 1334714-66-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16980A.
Eravacycline dihydrochloride
Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L). Category: Active pharmaceutical ingredients. CAS No. 1334714-66-7. Product ID: API1334714667. Molecular formula: C27H33Cl2FN4O8. Mole weight: 631.48.
Eravacycline Impurity 1
Eravacycline Impurity 1. Uses: For analytical and research use. CAS No. 1207283-91-7. Molecular formula: C27H31FN4O9. Mole weight: 574.56. Catalog: APB1207283917.
Eravacycline Impurity 2
Eravacycline Impurity 2. Uses: For analytical and research use. CAS No. 2204281-07-0. Molecular formula: C28H33FN4O8. Mole weight: 572.59. Catalog: APB2204281070.
Eravacycline Impurity 3
Eravacycline Impurity 3. Uses: For analytical and research use. CAS No. 2204281-08-1. Molecular formula: C28H33FN4O8. Mole weight: 572.59. Catalog: APB2204281081.
Eravacycline Impurity 4
Eravacycline Impurity 4. Uses: For analytical and research use. CAS No. 1207283-96-2. Molecular formula: C30H35FN4O8. Mole weight: 598.63. Catalog: APB1207283962.
ERB 041
ERB 041 is a potent ER β agonist; displays >200-fold selectivity for ER β over ERα (IC50 values are 5 and 1216 nM for human ER β and ERα; 3.1 and 620 nM for rat ER β and ERα; and 3.7 and 750 nM for mouse ER β and ERα respectively). Group: Biochemicals. Alternative Names: 7-Ethenyl-2-(3-fluoro-4-hydroxyphenyl)-5-benzoxazolol; 2-(3-Fluoro-4-hydroxyphenyl)-7-vinyl-1,3-benzoxazol-5-ol; 2-(3-Fluoro-4-hydroxyphenyl)-7-vinylbenzoxazol-5-ol; Prinaberel. Grades: Highly Purified. CAS No. 524684-52-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
ErbB-2-binding peptide
ErbB-2-binding peptide (HER2-binding peptide) is a tumor-binding peptide. ErbB-2-binding peptide has the potential for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HER2-binding peptide. CAS No. 562791-56-4. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P4082.
ERBB2IP protein (1003-1018)
ERBB2IP protein (1003-1018), a fragment of ERBB2IP protein, consists of amino acid residues 1003 to 1018. ERBB2IP protein has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternative Names: Erbin (1003-1018).
ERBB agonist-1
ERBB agonist-1 (Compound EF-1) is an agonist for ERBB4, that activates the ERBB4 signaling pathway by inducing dimerization of the ERBB4 receptor with an EC50 of 10.5 μM. ERBB agonist-1 induces phosphorylation of Akt and ERK1/2, reduces the collagen expression in cardiac fibroblasts, inhibits H2O2-induced cardiomyocyte death and Ang II (HY-13948)-induced cardiomyocyte hypertrophy. ERBB agonist-1 prevents fibrosis and exhibits cardioprotective efficacy in mouse models[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 930856-19-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-168438.