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Eribulin Impurity 5. Uses: For analytical and research use. Molecular formula: C40H59NO11. Mole weight: 729.90. Catalog: APB05782.
Eribulin Impurity 6
Eribulin Impurity 6. Uses: For analytical and research use. Molecular formula: C40H61NO12. Mole weight: 747.91. Catalog: APB05783.
Eribulin Impurity 7
Eribulin Impurity 7. Uses: For analytical and research use. Alternative Names: methyl 2-((2R,4aS,6S,7R,8S,8aS)-7,8-bis((tert-butyldimethylsilyl)oxy)-6-((S,E)-1-((tert-butyldimethylsilyl)oxy)-3-iodoallyl)octahydropyrano[3,2-b]pyran-2-yl)acetate. CAS No. 157322-83-3. Molecular formula: C32H63IO7Si3. Mole weight: 771.00. Catalog: APB157322833.
Eribulin Impurity 8
Eribulin Impurity 8. Uses: For analytical and research use. Alternative Names: 3-((2S,5S)-5-(2-((2S,4R,6R)-6-(((2S,3S,4R,5R)-5-((S)-2,3-bis((tert-butyldimethylsilyl)oxy)propyl)-4-methoxy-3-((phenylsulfonyl)methyl)tetrahydrofuran-2-yl)methyl)-4-methyl-5-methylenetetrahydro-2H-pyran-2-yl)ethyl)-4-methylenetetrahydrofuran-2-yl)propan-1-ol. CAS No. 253128-10-8. Molecular formula: C45H78O9SSi2. Mole weight: 851.33. Catalog: APB253128108.
Eribulin Impurity 9
Eribulin Impurity 9. Uses: For analytical and research use. CAS No. 253128-17-5. Molecular formula: C47H64O14S. Mole weight: 885.08. Catalog: APB253128175.
Eribulin Impurity 9
Eribulin Impurity 9. Uses: For analytical and research use. Molecular formula: C40H61NO12. Mole weight: 747.91. Catalog: APB05781.
Eribulin mesylate
Eribulin mesylate is an inhibitor for microtubule. Eribulin mesylate inhibits the proliferation of cancer cell LM8 and Dunn, inhibits the cell migration of LM8, arrests the cell cycle at G2/M phase, and induces apoptosis in LM8. Eribulin mesylate exhibits antitumor efficacy in mouse model[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: B1939 mesylate; E7389 mesylate; ER-086526 mesylate. CAS No. 441045-17-6. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13442A.
Eribulin Mesylate
Eribulin Mesylate is an antitumor drug that can be used to treat patients with metastatic breast cancer. It inhibits the proliferation of cancer cells by binding tubulin and microtubules. Eribulin Mesylate can inhibit experimental metastasis of breast cancer cells by reversing phenotype from epithelial-mesenchymal transition (EMT) to mesenchymal-epithelial transition (MET) states. Uses: The treatmnet of breast cancer. Alternative Names: 11,15:18,21:24,28-Triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one, 2-[(2S)-3-amino-2-hydroxypropyl]hexacosahydro-3-methoxy-26-methyl-20,27-bis(methylene)-, (2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-, methanesulfonate (1:1); 11,15:18,21:24,28-Triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one, 2-[(2S)-3-amino-2-hydroxypropyl]hexacosahydro-3-methoxy-26-methyl-20,27-bis(methylene)-, (2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-, methanesulfonate (salt); E 7389 methanesulfonate; Halaven; Eribulin monomethanesulfonate. Grades: ≥95%. CAS No. 441045-17-6. Molecular formula: C41H63NO14S. Mole weight: 826.01.
Eribulin Related Compound 13
Eribulin Related Compound 13. Uses: For analytical and research use. Alternative Names: 3-((2S,5S)-5-((3R,5R)-3-hydroxy-6-iodo-5-methylhept-6-en-1-yl)-4-methylenetetrahydrofuran-2-yl)propyl pivalate. CAS No. 157322-47-9. Molecular formula: C21H35IO4. Mole weight: 478.40. Catalog: APB157322479.
Eribulin Related Compound 14
Eribulin Related Compound 14. Uses: For analytical and research use. Alternative Names: 2-((2S,3S,4R,5R)-5-((S)-2,3-bis((tert-butyldimethylsilyl)oxy)propyl)-4-methoxy-3-((phenylsulfonyl)methyl)tetrahydrofuran-2-yl)acetaldehyde. CAS No. 871348-24-2. Molecular formula: C29H52O7SSi2. Mole weight: 600.95. Catalog: APB871348242.
Eribulin Related Compound 15
Eribulin Related Compound 15. Uses: For analytical and research use. Alternative Names: 2-((2R,3R,4R,5S)-5-((S)-2,3-bis((tert-butyldimethylsilyl)oxy)propyl)-4-methoxy-3-(tosylmethyl)tetrahydrofuran-2-yl)acetaldehyde. CAS No. 1808153-90-3. Molecular formula: C30H54O7SSi2. Mole weight: 614.98. Catalog: APB1808153903.
Ericamycin
Ericamycin is an antibiotic produced by Streptomyces varius SE-548. It has anti-gram-positive bacteria and mycobacterial activity, and can inhibit the growth of Ehrlich ascites cancer in mice and prolong survival time. Alternative Names: Eriamycin. CAS No. 11052-01-0. Molecular formula: C28H21NO8. Mole weight: 499.47.
Ericin A
Ericin A is a bacteriocin from Bacillus subgroups that has been reported to only inhibit the growth of gram-positive bacteria.
Ericin S
Ericin S is a bacteriocin from Bacillus subgroups that has been reported to only inhibit the growth of gram-positive bacteria.
Erigeroside
Erigeroside. Group: Biochemicals. Alternative Names: 4-Pyrone-3-beta-D-glucopyranoside. Grades: Plant Grade. CAS No. 59219-76-0. Pack Sizes: 10mg. Molecular Formula: C11H14O8, Molecular Weight: 274.223999999999. US Biological Life Sciences.
Worldwide
Erinacine A
Erinacine A, derived from the Lion's Mane mushroom (Hericium erinaceus), is a bioactive compound with demonstrated anticancer, antitumor, and neuroprotective properties. It induces cancer cell death through the generation of reactive oxygen species (ROS) and is believed to modulate signaling pathways involved in cancer cell apoptosis. Additionally, Erinacine A exhibits neuroprotective effects against neurodegenerative diseases such as Parkinson's and Alzheimer's, potentially mitigating related pathological symptoms. Alternative Names: Cyclohept[e]indene-8-carboxaldehyde, 2,3,3a,4,5,5a,6,7-octahydro-3a,5a-dimethyl-1-(1-methylethyl)-6-(β-D-xylopyranosyloxy)-, (3aR,5aR,6S)-; (3aR,5aR,6S)-2,3,3a,4,5,5a,6,7-Octahydro-3a,5a-dimethyl-1-(1-methylethyl)-6-(β-D-xylopyranosyloxy)cyclohept[e]indene-8-carboxaldehyde; Cyclohept[e]indene-8-carboxaldehyde, 2,3,3a,4,5,5a,6,7-octahydro-3a,5a-dimethyl-1-(1-methylethyl)-6-(β-D-xylopyranosyloxy)-, [3aR-(3aα,5aβ,6α)]-; (+)-Erinacin A; Erinacin A; (3aR,5aR,6S)-3a,5a-Dimethyl-1-(propan-2-yl)-6-{[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxy}-2H,3H,3aH,4H,5H,5aH,6H,7H-cyclohepta[e]indene-8-carbaldehyde; (3aR,5aR,6S)-8-Formyl-1-isopropyl-3a,5a-dimethyl-2,3,3a,4,5,5a,6,7-octahydrocyclohepta[e]inden-6-yl β-D-xylopyranoside. Grades: ≥95% by HPLC. CAS No. 156101-08-5. Molecular formula: C25H36O6. Mole weight: 432.55.
Erinacine C
Erinacine C is a bioactive compound derived from the Hericium erinaceus mushroom, known for its potential neuroprotective properties. It is a cyathane diterpenoid with a unique chemical structure that has been studied for its ability to stimulate the synthesis of nerve growth factor (NGF), which can be beneficial in treating nervous system diseases such as Alzheimer's. Alternative Names: β-D-Xylopyranose, 1,2-O-[(3aR,5aR,6R,7R,10aR)-2,3,3a,4,5,5a,6,7,10,10a-decahydro-8-(hydroxymethyl)-3a,5a-dimethyl-1-(1-methylethyl)cyclohept[e]indene-6,7-diyl]-; 1,2-O-[(3aR,5aR,6R,7R,10aR)-2,3,3a,4,5,5a,6,7,10,10a-Decahydro-8-(hydroxymethyl)-3a,5a-dimethyl-1-(1-methylethyl)cyclohept[e]indene-6,7-diyl]-β-D-xylopyranose; β-D-Xylopyranose, 1,2-O-[2,3,3a,4,5,5a,6,7,10,10a-decahydro-8-(hydroxymethyl)-3a,5a-dimethyl-1-(1-methylethyl)cyclohept[e]indene-6,7-diyl]-, [3aR-(3aα,5aβ,6α,7β,10aα)]-; Erinacin C. Grades: ≥95% by HPLC. CAS No. 156101-09-6. Molecular formula: C25H38O6. Mole weight: 434.57.
Erinacine C
Erinacine C is the inhibitor for NF-κB signaling pathway and the activator for Nrf2 signaling pathway. Erinacine C exhibits antioxidant, neuroprotective and anti-inflammatory effects[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 156101-09-6. Pack Sizes: 500 μg; 1 mg. Product ID: HY-N11004.
Erinacine E
Erinacine E is a k opioid receptor agonist produced by Hericium ramosum CL24240. Alternative Names: (-)-Erinacine E. Molecular formula: C25H36O6. Mole weight: 432.55.
Eriobrucinol methyl ether
Eriobrucinol methyl ether. Alternative Names: 1H,7H-4,6-Dioxacyclobut[1,7]indeno[5,6-b]naphthalen-7-one, 1a,2,3,3a,10b,10c-hexahydro-10-methoxy-1,1,3a-trimethyl-, [1aR-(1aα,3aα,10bα,10cα)]-. CAS No. 42259-10-9. Molecular formula: C20H22O4. Mole weight: 326.39.
Eriocalyxin B
Eriocalyxin B, isolated from the herbs of Isodon eriocalyx, is a potent NF-kappaB inhibitor. Eriocalyxin B inhibited the NF-kappaB transcriptional activity but not that of cAMP response element-binding protein. eriocalyxin B reversibly interfered with the binding of p65 and p50 subunits to the DNA in a noncompetitive manner. Eriocalyxin B exerts potent antiinflammatory effects through selective modulation of pathogenic Th1 and Th17 cells by targeting critical signaling pathways. Besides, Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways. Eriocalyxin B should be considered a candidate for pancreatic cancer treatment. Uses: Antiinflammatory. Alternative Names: Rabdosianone. Grades: >98%. CAS No. 84745-95-9. Molecular formula: C20H24O5. Mole weight: 344.4.
Eriochrome Black A
Eriochrome Black A. Group: Biochemicals. Alternative Names: 1-Naphthalene sulfonic acid. Grades: Highly Purified. CAS No. 3618-58-4. Pack Sizes: 1g, 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
Eriochrome Black T
Eriochrome Black T. Uses: For analytical and research use. Alternative Names: 1-(1-Hydroxy-2-naphthylazo)-6-nitro-2-naphthol-4-sulfonic Acid Sodium Salt; Mordant Black 11. CAS No. 1787-61-7. Molecular formula: C20H12N3NaO7S. Mole weight: 461.38. Catalog: APB1787617.
Eriochrome Black T (C.I. 14645)
25g Pack Size. Group: Stains & Indicators. Formula: C20H12N3NaO7S. CAS No. 1787-61-7. Prepack ID 51499212-25g. Molecular Weight 461.38. See USA prepack pricing.
Eriochrome Blue Black R
Eriochrome Blue Black R. Group: Biochemicals. Alternative Names: Mordant Black 17; CI 1575. Grades: Highly Purified. CAS No. 2538-85-4. Pack Sizes: 1kg. US Biological Life Sciences.
Worldwide
Eriochrome Blue Black R ≥72% (Dye content)
Eriochrome Blue Black R ≥72% (Dye content). Group: Biochemicals. Grades: Reagent Grade. CAS No. 2538-85-4. Pack Sizes: 25g, 100g, 1Kg. US Biological Life Sciences.
Worldwide
Eriochrome cyanine R
100g Pack Size. Group: Stains & Indicators. Formula: C23H15Na3O9S. CAS No. 3564-18-9. Prepack ID 53361433-100g. Molecular Weight 536.4. See USA prepack pricing.
Eriochrome Cyanine R
Eriochrome Cyanine R. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
Worldwide
Eriochrome® Cyanine R
Eriochrome® Cyanine R. Group: Biochemicals. Grades: Highly Purified. CAS No. 3564-18-9. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C23H15Na3O9S. US Biological Life Sciences.
Worldwide
Eriocitrin
Eriocitrin is a powerful antioxidative flavonoid in lemon with lipid-lowering effects in a rat model of high-fat diet. It might play an important role in the control of the change in glutathione redox status in rat liver during exercise. These findings showed that Eriocitrin was effective in the prevention of oxidative damages caused by acute exercise-induced oxidative stress. Eriocitrin was suggested to be metabolized by intestinal bacteria, and then eriodictyol and 3,4-dihydroxyhydrocinnamic of its metabolite were absorbed. Following administration of Eriocitrin, plasma exhibited an elevated resistance effect to lipid peroxidation. Eriocitrin metabolites functioning as antioxidant agents are discussed. Uses: Antioxidant. Alternative Names: (S)-3',4',5,7-TETRAHYDROXYFLAVANONE-7-[6-O-(ALPHA-L-RHAMNOPYRANOSYL)-BETA-D-GLUCOPYRANOSIDE]; ERIOCITRIN; ERIODICTYL-7-RUTINOSIDE; ERIODICTYOL-7-O-RUTINOSIDE; ERIODICTYOL-7-RUTINOSIDE; (S)-7-[[6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-4H-benzopyran-4-one; (s)-3',4',5,7-tetrahydroxyflavanone-7-[6-o-(α-l-rhamnopyranosyl)-β-d-glucopyranoside]; (2S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxymethyl]oxan-2-yl]oxy-chroman-4-one. Grades: >98%. CAS No. 13463-28-0. Molecular formula: C27H32O15. Mole weight: 596.53.
Eriocitrin
Eriocitrin is a flavonoid isolated from lemons that is a powerful antioxidant. Eriocitrin inhibits the proliferation of liver cancer cells by arresting the cell cycle in the S phase by upregulating p53, cyclin A, cyclin D3 and CDK6. Eriocitrin triggers apoptosis by activating intrinsic signaling pathways involving mitochondria[1][1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Eriodictyol 7-rutinoside; Eriodictyol 7-O-rutinoside. CAS No. 13463-28-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0636.
Eriodermin
It is a dichlorodepsidone from the lichen erioderma physcioides. Alternative Names: 11H-Dibenzo[b,e][1,4]dioxepin-4-carboxaldehyde, 2,7-dichloro-3-hydroxy-8-methoxy-1,6-dimethyl-11-oxo-; 2,8-dichloro-9-hydroxy-3-methoxy-1,7-dimethyl-6-oxobenzo[b][1,4]benzodioxepine-10-carbaldehyde; 4-formyl-2,7-dichloro-3-hydroxy-8-methoxy-1,6-dimethyldi-benzo[b,e][1,4]dioxepin-11-one; Eriodermine. CAS No. 92070-80-9. Molecular formula: C17H12Cl2O6. Mole weight: 383.18.
Eriodictyol
Eriodictyol ((±)-Huazhongilexone; Dihydroluteolin) is an orally active TRPV1 receptor antagonist (IC50=44-47 nM, rTRPV1) with antioxidant and anti-inflammatory activities. Eriodictyol effectively inhibits lipid peroxidation and the release of proinflammatory cytokines by specifically antagonizing the TRPV1 receptor and activating the Nrf2 signaling pathway. Eriodictyol reduces the levels of ICAM-1, VEGF, eNOS and TNF-α in the retina and maintains the integrity of the blood-retinal barrier. Eriodictyol alleviates oxidative stress-induced apoptosis and hyperalgesia, enhances the activity and cytotoxicity of immune cells (such as B lymphocytes, NK cells and macrophages), and increases the levels of antioxidant enzymes simultaneously. Eriodictyol can be used in the research of diabetic retinopathy, acute lung injury and various pain-related diseases[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Huazhongilexone. CAS No. 552-58-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-N0637.
Eriodictyol
Eriodictyol. CAS No. 552-58-9/4049-38-1. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
Eriodictyol
Eriodictyol is a flavanone characteristic of lime, found mainly in juice. The glycosylated forms are eriocitrin (bound to a rutinoside) and neoeriocitrin (bound to a neohesperidose). Eriodictyol prevents some secondary effects of diabetes, such as diabetic retinopathy and biochemical changes in plasma (study in rats) (Bucolo et al., 2012). In addition, it has been reported that in in vitro studies, eriodictyol decreases insulin resistance and glucose absorption.Eriodictyol is used in biological studies as natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation. Eriodictyl is extracted from Yerba santa, an herb. The leaf is used to make medicine.Yerba santa is used for respiratory conditions including coughs, colds, tuberculosis, asthma, and chronic bronchitis. It is also used for fever and dry mouth. Some people use it to relieve muscle spasms, to loosen phlegm, and as a tonic. Group: Biochemicals. Alternative Names: (2S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one; (2S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one; 3',4',5,7-tetrahydroxy-flavanone; (+)-Eriodictyol; (2S)-Eriodictyol; (S)-3',4',5,7-Tetrahydroxyflavanone; 3',4',5,7-Tetrahydroxyflavanone; Huazhongilexone. Grades: Highly Purified. CAS No. 552-58-9. Pack Sizes: 10mg, 20mg, 50mg, 100mg. Molecular Formula: C15H12O6, Molecular Weight: 288.25. US Biological
Worldwide
Eriodictyol
Eriodictyol is a natural flavonoid found in the fruits of Citrus sinensis (L.) Osbeck. Eriodictyol exhibits activities of antidiabetic, anti-inflammatory and antioxidant. Eriodictyol can increases glucose uptake and improves insulin resistance. Alternative Names: (S)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4-benzopyrone; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one; 3',4',5,7-tetrahydroxyflavanone; 4H-1-benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-. Grades: >97%. CAS No. 552-58-9. Molecular formula: C15H12O6. Mole weight: 288.25.
Eriodictyol 7,3'-dimethyl ether
Eriodictyol 7,3'-dimethyl ether is a natural compound isolated from the herbs of Blumea balsamifera. Alternative Names: (2S)-5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy-2,3-dihydrochromen-4-one. Grades: 98.0%. CAS No. 54352-60-2. Molecular formula: C17H16O6. Mole weight: 316.30.
Eriodictyol 7-O-glucoside
Eriodictyol 7-O-glucoside is isolated from the herbs of Dracocephalum rupestre. It has protective effect on cisplatin-induced toxicity. Alternative Names: (S)-2-(3,4-dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-2,3-dihydro-5-hydroxy-4H-1-benzopyran-4-one; eriodictyol-7-glucoside. Grades: 95%. CAS No. 38965-51-4. Molecular formula: C21H22O11. Mole weight: 450.39.
Eriodictyol-7-O-glucoside
Eriodictyol-7-O-glucoside (Eriodictyol 7-O-β-D-glucoside), a flavonoid, is an Nrf2 activator. Eriodictyol-7-O-glucoside exhibits significant scavenging effects on both hydroxyl radicals and superoxide anions, with IC50 values of 0.28 mM and 0.30 mM, respectively. Eriodictyol-7-O-glucoside increases the nuclear localization of Nrf2 and induces the expression of the Nrf2/ARE-dependent genes. Eriodictyol-7-O-glucoside provides protection against oxygen and glucose deprivation (OGD)-induced oxidative insult. Eriodictyol-7-O-glucoside demonstrates neuroprotective efficacy in a rat model of focal cerebral ischemia (MCAO). Eriodictyol-7-O-glucoside can be used for the study of stroke[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Eriodictyol 7-O-β-D-glucoside. CAS No. 38965-51-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N3847.
It is a colorant for foods and other substances to induce a color change. It is denoted by E number E133 and has a color index of 42090. Alternative Names: 1206blue; abcolbluenb; acidblue9,disodium; acidblue9,disodiumsalt; aizenfoodblueno.2; blue1206; brilliantbluefcdno.1; brilliantbluefcfsupra. Grades: biological stain. CAS No. 3844-45-9. Molecular formula: C37H34N2Na2O9S3. Mole weight: 792.85.
Eriosema Psoraleoides Powder
Eriosema Psoraleoides Powder.
CA, FL & NJ
Eriostemoic acid
Eriostemoic acid. Alternative Names: 2H,8H-Benzo[1,2-b:3,4-b']dipyran-6-propionic acid, 5-methoxy-2,2,8,8-tetramethyl- (7CI,8CI); 5-Methoxy-2,2,8,8-tetramethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-6-propanoic acid. CAS No. 26535-36-4. Molecular formula: C20H24O5. Mole weight: 344.4.
Erismodegib
Erismodegib. Group: Biochemicals. Alternative Names: rel-N-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)-1,1'-biphenyl]-3-carboxamide; LDE 225; NVP-LDE 225. Grades: Highly Purified. CAS No. 956697-53-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C26H26F3N3O3. US Biological Life Sciences.
Worldwide
Eritadenine
Hypocholesterolemic isolated from shiitake mushrooms, effecting phospholipid and linoleic acid metabolisms. Specifically, Eritadenine is a potent inhibitor of S-adenosyl-L-homocysteine hydrolase (SAHH), decreasing total cholesterol levels in plasma. Group: Biochemicals. Alternative Names: (αR, βR)-6-Amino-α, β-dihydroxy-9H-purine-9-butanoic Acid; 4-(6-Amino-9H-purin-9-yl)-4-deoxy-D-erythronic Acid; 4-(6-Aminopurin-9-yl)-4-deoxy-D-erythronic Acid; Lentinacin; Lentysine; 4-(9-Adenyl)-D-erythro-2,3-dihydroxybutyric Acid; D-Eritadenine. Grades: Highly Purified. CAS No. 23918-98-1. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
ERK1/2 inhibitor 1
ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2095719-90-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112287.
ERK5-IN-1
ERK5-IN-1 is a potent ERK5 inhibitor with an IC50 of 87±7 nM. ERK5-IN-1 also inhibits LRRK2[G2019S] with an IC50 of 26 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1234479-76-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14403.
ERK5-IN-2
ERK5-IN-2 is an orally active, sub-micromolar, selective ERK5 inhibitor with IC50s of 0.82 μM, 3 μM for ERK5 and ERK5 MEF2D, respectively. ERK5-IN-2 does not interact with the BRD4 bromodomain. ERK5-IN-2 suppresses both tumor xenograft growth and basic fibroblast growth factor (bFGF) driven Matrigel plug angiogenesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1888305-96-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128341.
ER-Laurdan
ER-Laurdan is a derivative of the membrane-permeable fluorescent probe Laurdan (HY-D0080) that targets the endoplasmic reticulum (ER). As a membrane fluidity reporter, ER-Laurdan specifically localizes to the ER luminal membrane, and exhibits a prominent solvatochromic response to fluidity changes caused by membrane packing and exogenous saturated fatty acid stress. ER-Laurdan shows no overlapping localization with mitochondria, enables quantitative analysis of ER membrane fluidity via generalized polarization ratio measurement, and allows automatic signal masking with the help of ER markers. With high specificity and quantitative capability, ER-Laurdan serves as an important tool for investigating metabolic disorders and associated changes in the physical properties of cell membranes[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3091879-77-2. Pack Sizes: 1 mg. Product ID: HY-N16308.
Erlizumab
Erlizumab (rhuMAb) is a monoclonal antibody against the Integrin b2/ITGB2/CD18 subunit of the Mac-1 receptor. Erlizumab can reduce reperfusion injury in myocardial infarction[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: rhuMAb. CAS No. 211323-03-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99946.
Erlose
Erlose is a widely utilized pharmaceutical in the biomedical sector, serving as a prominent role for studying Type 2 diabetes. Its mechanism of action entails augmenting glycemic regulation while concurrently amplifying the responsiveness of cells towards insulin. Alternative Names: a-D-Glc-(1→4)-a-D-Glc-(1→2)-b-D-Fru; a-Maltosyl b-fructofuranoside; β-D-Fructofuranosyl O-α-D-glucopyranosyl-(1→4)-α-D-glucopyranoside; Fructomaltose. CAS No. 13101-54-7. Molecular formula: C18H32O16. Mole weight: 504.44.
Erlose
Erlose. CAS No. 13101-54-7. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
Erlosiban
Erlosiban, an iminopyrrolidin derivative, has been found to be a nonpeptide oxytocin receptor antagonist that could probably be used in the treatment of female infertility and preterm labour. It is still under Phase II clinical trail in Preterm labour. Alternative Names: UOBE-001; OBE001; OBE001; NII-3765U8A1EC; CHEMBL1254025; 3765U8A1EC; Erlosiban; Erlosiban [INN]; [(2S,4Z)-2-(hydroxymethyl)-4-methoxyiminopyrrolidin-1-yl]-[4-(2-methylphenyl)phenyl]methanone. Grades: 98%. CAS No. 1477482-19-1. Molecular formula: C20H22N2O3. Mole weight: 338.41.
Erlotinib
Erlotinib is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. Erlotinib has been indicated for non-small cell lung cancer (NSCLC) and pancreatic cancer therapy. Alternative Names: CP358774; CP 358774; CP-358774; NSC 718781; NSC718781; NSC-718781. Grades: >98%. CAS No. 183321-74-6. Molecular formula: C22H23N3O4. Mole weight: 393.44.
Erlotinib
Erlotinib. Uses: For analytical and research use. Alternative Names: N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine. CAS No. 183321-74-6. Molecular formula: C22H23N3O4. Mole weight: 393.44. Catalog: APB183321746.
Erlotinib
Erlotinib (CP-358774) is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer[1]. Erlotinib is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CP-358774; NSC 718781; OSI-774. CAS No. 183321-74-6. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-50896.
Erlotinib-3-vinyl Hydrochloride
A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Alternative Names: 6,7-Bis(2-methoxyethoxy)-N-(3-vinylphenyl)quinazolin-4-amine hydrochloride; 4-Quinazolinamine, N-(3-ethenylphenyl)-6,7-bis(2-methoxyethoxy)-, hydrochloride (1:1). Grades: 95%. CAS No. 1624294-38-7. Molecular formula: C22H26ClN3O4. Mole weight: 431.91.
Erlotinib (CP-358774)
Erlotinib is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. Erlotinib induces autophagy. Group: Inhibitors. Alternative Names: CP358774, NSC 718781,OSI-774. CAS No. 183321-74-6. Pack Sizes: 50mg. Product ID: S7786. Formula: C22H23N3O4. Smiles: COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Erlotinib-d6
Erlotinib-d6 (CP-358774 D6) is a deuterium labeled Erlotinib (CP-358774). Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR[1]. Erlotinib-d6 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CP-358774-d6; NSC 718781-d6; OSI-774-d6. CAS No. 1034651-23-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-50896S.
Erlotinib-[d6] Hydrochloride
Erlotinib-[d6] Hydrochloride is the labelled analogue of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Erlotinib is a medication used to treat non-small cell lung cancer and pancreatic cancer. Alternative Names: N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy-d3)-4-quinazolinamine Hydrochloride; 6,7-Bis(2-methoxyethoxy-d3)-4-(3-ethynylanilino)quinazoline Hydrochloride; [6,7-Bis(2-methoxyethoxy-d3)quinazolin-4-yl]-(3-ethynylphenyl)amine Hydrochloride; Erlotinib D6 Hydrochloride. Grades: 98% by CP; 98% atom D. CAS No. 1189953-78-3. Molecular formula: C22H18D6ClN3O4. Mole weight: 435.93.
Erlotinib hydrochloride
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C22H24ClN3O4. CAS No. 183319-69-9. Prepack ID 82977875-1g. Molecular Weight 429.9. See USA prepack pricing.
Erlotinib hydrochloride
Erlotinib HCl potently inhibits EGFR activation in intact cells including HNS human head and neck tumor cells (IC50 = 20 nM), DiFi humancolon cancer cells and MDA MB-468 human breast cancer cells. Uses: Antineoplastic agents. Alternative Names: OSI-744; OSI744; OSI 744; Tarceva; 4-(m-Ethynylanilino)-6,7-bis(2-methoxyethoxy)quinazoline monohydrochloride; 6,7-bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline hydrochloride. Grades: >98%. CAS No. 183319-69-9. Molecular formula: C22H23N3O4.HCl. Mole weight: 429.90.
Erlotinib Hydrochloride
Erlotinib Hydrochloride (CP-358774 Hydrochloride) inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib (Hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CP-358774 hydrochloride; NSC 718781 hydrochloride; OSI-774 hydrochloride. CAS No. 183319-69-9. Pack Sizes: 50 mg; 100 mg; 500 mg; 1 g; 10 g. Product ID: HY-12008.
Erlotinib Hydrochloride
Erlotinib hydrochloride is a small-molecule tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR). It is available as oral tablets and represents a targeted therapy for certain non-small cell lung cancers and pancreatic cancer. The drug reversibly binds to the intracellular kinase domain of EGFR, blocking downstream signaling pathways critical for tumor cell proliferation and survival. Applications: It is indicated for the first-line treatment of metastatic non-small cell lung cancer harboring egfr exon 19 deletions or exon 21 (l858r) substitution mutations, as detected by an fda-approved test. it is also indicated for maintenance therapy in patients with locally advanced or metastatic nsclc following stabilization after first-line platinum-based chemotherapy. additionally, it is approved in combination with gemcitabine for the first-line treatment of locally advanced, unresectable, or metastatic pancreatic cancer. rash and diarrhea are the most common dose-limiting toxicities. Category: Anti-tumor apis. Synonyms: erlotinib HCl; Tarceva; OSI-774; CP 358774; DA87705X9K; CP-358. CAS No. 183319-69-9. Product ID: API183319699. Molecular formula: C22H24ClN3O4. Mole weight: 429.9. EINECS: 620-491-0. InChIKey: GTTBEUCJPZQMDZ-UHFFFAOYSA-N. Appearance: White to off-white powder.
A free base form of the EGFR inhibitor Erlotinib Hydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 183321-74-6. Pack Sizes: 100mg, 1g. US Biological Life Sciences.
Worldwide
Erlotinib impurity 1
Erlotinib impurity 1. Uses: For analytical and research use. CAS No. 1809951-10-7. Molecular formula: C28H34N4O9. Mole weight: 570.6. Catalog: APB1809951107.
Erlotinib Impurity 1
Erlotinib Impurity 1. Uses: For analytical and research use. Alternative Names: 4-chloro-6,7-bis(2-chloroethoxy)quinazoline. CAS No. 183322-21-6. Molecular formula: C12H11Cl3N2O2. Mole weight: 319.99. Catalog: APB183322216.
Erlotinib Impurity 10
Erlotinib Impurity 10. Uses: For analytical and research use. Alternative Names: N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine. CAS No. 183319-69-9. Molecular formula: C22H23N3O4. Mole weight: 393.17. Catalog: APB183319699.
Erlotinib Impurity 12
Erlotinib Impurity 12. Uses: For analytical and research use. Alternative Names: 2-amino-4,5-bis(2-methoxyethoxy)benzamide. CAS No. 236750-62-2. Molecular formula: C13H20N2O5. Mole weight: 284.14. Catalog: APB236750622.
Erlotinib Impurity 13
Erlotinib Impurity 13. Uses: For analytical and research use. Alternative Names: 6,7-bis(2-methoxyethoxy)quinazolin-4(3H)-one. CAS No. 179688-29-0. Molecular formula: C14H18N2O5. Mole weight: 294.12. Catalog: APB179688290.