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A mixture of semi-synthetic Avermectins; containing 90% or more of component B1a and 10% or less of component B1b. Antiparasitic. Group: Biochemicals. Alternative Names: (4''R)-4''-(Acetylamino)-4''-deoxyavermectin B1; Eprinex; MK 397. Grades: Highly Purified. CAS No. 123997-26-2. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Eprinomectin B1a
It is a semi-synthetic 4''-epimethylamino analogue of avermectin B1b prepared by oxidation of the 4''-hydroxy moiety and reductive amination. Members of the Avermectin/Milbemycin class exert their insecticidal/anthelmintic effects by binding to glutamate-gated chloride channels expressed on nematode neurones and pharyngeal muscle cells. Synonyms: (4''R)-4''-(Acetylamino)-5-O-demethyl-4''-deoxyavermectin A1a; Avermectin A1a, 4'-(acetylamino)-5-O-demethyl-4'-deoxy-, (4'R)-; Eprinomectin component B1a. Grade: >99% by HPLC. CAS No. 133305-88-1. Molecular formula: C50H75NO14. Mole weight: 914.13.
Eprinomectin B1b
It is a semi-synthetic analogue of avermectin B1b prepared by oxidation of the 4''-hydroxy moiety and reductive amination followed by acetylation. It is the minor component (<10%) of the commercial product for endo- and exo-parasite control, eprinomectin. It is a potent insecticide and acaricide. Synonyms: (4''R)-4''-(Acetylamino)-5-O-demethyl-25-de(1-methylpropyl)-4''-deoxy-25-(1-methylethyl)avermectin A1a; Eprinomectin component B1b. Grade:>99% by HPLC. CAS No. 133305-89-2. Molecular formula: C49H73NO14. Mole weight: 900.10.
Eprinomectin-[d3]
One of the isotope labelled form of Eprinomectin, which could be used as an antiparasitic agent. Synonyms: (4''R)-4''-(Acetylamino)-5-O-demethyl-4''-deoxyavermectin A1a-d3 compound with (4''R)-4''-(Acetylamino)-5-O-demethyl-25-de(1-methylpropyl)-4''-deoxy-25-(1-methylethyl)avermectin A1a-d3. Molecular formula: C50D3H72NO14.C49D3H70NO14. Mole weight: 917.17 (B1a); 903.14 (B1b).
Epristeride
Epristeride is a medication primarily used to treat benign prostatic hyperplasia (BPH), which is an enlarged prostate gland. Epristeride is a 5-alpha-reductase inhibitor. It works by inhibiting the enzyme 5-alpha-reductase, which converts testosterone to dihydrotestosterone (DHT). DHT is a potent androgen that contributes to prostate growth. By reducing DHT levels, epristeride helps decrease the size of the prostate and alleviate symptoms of BPH. Epristeride is used to manage symptoms of BPH, such as difficulty in urination, increased urinary frequency, and urinary retention. Synonyms: ONO-9302; 17β-(tert-Butylaminocarbonyl)androsta-3,5-diene-3-carboxylic acid; Androsta-3,5-diene-3-carboxylic acid, 17-(((1,1-dimethylethyl)amino)carbonyl)-, (17β)-; SKF105657. Grade: 95%. CAS No. 119169-78-7. Molecular formula: C25H37NO3. Mole weight: 399.57.
Epristeride
Epristeride (ONO-9302) is a selective, specific and orally active uncompetitive inhibitor of human steroid 5 alpha-reductase isoform 2. Epristeride has inhibitory effects for SR isoenzymes types 2 with Ki value of 0.7-2 nM. Epristeride can be used for the research of prostatic hyperplasia and acne[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ONO-9302; SKF105657. CAS No. 119169-78-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-107385.
Eprobemide
Eprobemide is a reversible monoamine oxidase A (MAO-A) inhibitor and can be used as an antidepressant. Synonyms: LIS 630. Grade: 98%. CAS No. 87940-60-1. Molecular formula: C14H19ClN2O2. Mole weight: 282.769.
Eprociclovir
Eprociclovir, an acyclovir analogue, has been found to have antiviral activity especially against herpes virus. Synonyms: A-5021; A5021; A 5021; AV-10; AV10; AV 10; Eprociclovir. UNII-227AL47VGS; AV-10; AC1LAAHS; 227AL47VGS; CHEMBL285442; SCHEMBL4550680; 2-amino-9-[[(1S,2R)-1,2-bis(hydroxymethyl)cyclopropyl]methyl]-3H-purin-6-one. Grade: 98%. CAS No. 145512-85-2. Molecular formula: C11H15N5O3. Mole weight: 265.27.
Eprodisate disodium
Eprodisate disodium is a sulfonated inhibitor of fibrillogenesis which coul be used in the treatment of amyloid A (AA) amyloidosis. Uses: Used in the treatment of amyloid a (aa) amyloidosis. Synonyms: disodium; propane-1,3-disulfonate. Grade: > 98 %. CAS No. 36589-58-9. Molecular formula: C3H6Na2O6S2. Mole weight: 248.19.
Eprosartan
Eprosartan is an angiotensin II receptor blocker (ARB) used primarily for the treatment of hypertension (high blood pressure). Eprosartan blocks the action of angiotensin II, a hormone that causes blood vessels to constrict, thereby increasing blood pressure. By blocking angiotensin II receptors, eprosartan allows blood vessels to relax and widen, which helps lower blood pressure. Eprosartan is indicated for the treatment of hypertension to lower blood pressure and reduces the risk of cardiovascular events such as heart attack and stroke. Uses: Prototype of the imidazoleacrylic acid angiotensin ii receptor antagonists. antihypertensive. Synonyms: 2-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (αE)-; (αE)-α-[[2-Butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-2-thiophenepropanoic acid; 2-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (E)-; (E)-2-Butyl-1-(p-carboxybenzyl)-α-2-thenylimidazole-5-acrylic acid; Navixen; SKB 108566; SKF 108566; Teveten. Grade: 98%. CAS No. 133040-01-4. Molecular formula: C23H24N2O4S. Mole weight: 424.51.
Eprosartan
Eprosartan. Group: Biochemicals. Alternative Names: (E) -3-[2-Butyl-1-[ (4-carboxyphenyl) methyl]imidazol-5-yl]-2- (2-thienylmethyl) -2-propenoic acid; SKF-108566. Grades: Highly Purified. CAS No. 133040-01-4. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C23H24N2O4S. US Biological Life Sciences.
Worldwide
Eprosartan acyl glucuronide
A derivative of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Synonyms: (E)-3-[2-Butyl-1-[(4-carboxyphenyl)methyl]imidazol-5-yl]-2-(2-thienylmethyl)-2-propenoic Acid β-D-Glucuronide. Grade: > 95%. Molecular formula: C29H32N2O10S. Mole weight: 600.65.
Eprosartan-d3
Labeled Eprosartan, a prototype of the imidazoleacrylic acid angiotensin II receptor antagonists. Eprosartan is an antihypertensive. Group: Biochemicals. Alternative Names: (αE)-α-[[2-(Butyl-d3)-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-2-thiophenepropanoic Acid; (E)-2-(Butyl-d3)-1-(p-carboxybenzyl)-α-2-thenylimidazole-5-acrylic Acid; Navixen-d3; SKB 108566-d3; SKF 108566-d3; Teveten-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Eprosartan-[d3]
Eprosartan-[d3] is the labelled analogue of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Synonyms: Eprosartan D3; (αE)-α-[[2-(Butyl-d3)-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-2-thiophenepropanoic Acid; (E)-2-(Butyl-d3)-1-(p-carboxybenzyl)-α-2-thenylimidazole-5-acrylic Acid. Grade: 95% by HPLC; 95% atom D. CAS No. 1185243-70-2. Molecular formula: C23H21D3N2O4S. Mole weight: 427.53.
Eprosartan ethyl methyl diester
Eprosartan ethyl methyl diester. Group: Biochemicals. Alternative Names: (a-E) -a-[[2-Butyl-1-[[4- (methoxycarbonyl) phenyl]methyl]-1H-imidazol-5-yl]methylene]-2-thiophenepropanoic acid ethyl ester; Methyl 4-((5-((E)-2-(ethoxycarbonyl)-3-(thien-2-yl)prop-1-enyl)-2-butyl-1H-imidazol-1-yl)methyl)benzoate. Grades: Highly Purified. CAS No. 133486-13-2. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C26H30N2O4S. US Biological Life Sciences.
An impurity of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Synonyms: (E)-methyl 4-((2-butyl-5-(3-ethoxy-3-oxo-2-(thiophen-2-ylmethyl)prop-1-en-1-yl)-1H-imidazol-1-yl)methyl)benzoate. Grade: > 95%. Molecular formula: C26H30N2O4S. Mole weight: 466.60.
Eprosartan Impurity 2
An impurity of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Synonyms: 2-((2-butyl-1-(4-carboxybenzyl)-1H-imidazol-5-yl)methylene)malonic acid. Grade: > 95%. Molecular formula: C19H20N2O6. Mole weight: 372.38.
Eprosartan Impurity 3
An impurity of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Synonyms: (E)-4-((2-butyl-5-(2-carboxyvinyl)-1H-imidazol-1-yl)methyl)benzoic acid. Grade: > 95%. Molecular formula: C18H20N2O4. CH4O3S. Mole weight: 328.37 96.11.
Eprosartan Impurity 4
An impurity of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Synonyms: 4-((2-butyl-5-formyl-1H-imidazol-1-yl)methyl)benzoic acid. Grade: > 95%. CAS No. 152146-59-3. Molecular formula: C16H18N2O3. Mole weight: 286.33.
Eprosartan Impurity 5
An impurity of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Synonyms: (E)-4-((2-butyl-5-(3-carboxy-1,4-di(thiophen-2-yl)but-2-en-2-yl)-1H-imidazol-1-yl)methyl)benzoic acid. Grade: > 95%. Molecular formula: C28H28N2O4S2. Mole weight: 520.69.
Eprosartan mesylate
Eprosartan mesylate (SKF-108566J) is a selective, competitive, nonpeptid and orally active angiotensin II receptor antagonist, used as an antihypertensive. Eprosartan mesylate binds angiotensin II receptor with IC50s of 9.2 nM and 3.9 nM in rat and human adrenal cortical membranes, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SKF-108566J. CAS No. 144143-96-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15834A.
Eprosartan mesylate
Eprosartan mesylate. Group: Biochemicals. Grades: Purified. CAS No. 144143-96-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Eprosartan mesylate
Eprosartan mesylate. CAS No: 144143-96-4
Sarchem Laboratories New Jersey NJ
Eprosartan Mesylate
Eprosartan is a nonpeptide angiotensin II receptor antagonist, [3H]-eprosartan binds to the AT1 receptor with KD of 0.83 nM in rat vascular smooth muscle cells. Synonyms: 2-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (αE)-, methanesulfonate (1:1); 2-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (E)-, monomethanesulfonate; 2-Thiophenepropanoic acid, α-[[2-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-, (αE)-, monomethanesulfonate; Eprosartan methanesulfonate; SKF 108566J; SKF-108566J; SKF108566J. Grade: >98%. CAS No. 144143-96-4. Molecular formula: C23H24N2O4S.CH4O3S. Mole weight: 520.62.
Eprosartan RC A ( (E)-3-(2-Butyl-1H-imidazol-5-yl)-2-(thiophen-2-ylmethyl)acrylic acid(Debenzyl Eprosartan) )
Eprosartan RC A ( (E)-3-(2-Butyl-1H-imidazol-5-yl)-2-(thiophen-2-ylmethyl)acrylic acid(Debenzyl Eprosartan) )
Sarchem Laboratories New Jersey NJ
Eprosartan RC B (3-(Thiophen-2-yl)propanoic acid (Thiophenpropionic acid)
Eprosartan RC B (3-(Thiophen-2-yl)propanoic acid (Thiophenpropionic acid)
Sarchem Laboratories New Jersey NJ
Eprosartan RC C (2-[(Thiophene-2-yl)methyl] malonic acid (Bromomethylbenzoic acid))
Eprosartan RC C (2-[(Thiophene-2-yl)methyl] malonic acid (Bromomethylbenzoic acid))
Sarchem Laboratories New Jersey NJ
Eprosartan RC D (4-Bromomethylbenzoic acid (Bromomethylbenzoic acid))
Eprosartan RC D (4-Bromomethylbenzoic acid (Bromomethylbenzoic acid)). CAS No: 6232-88-8
Sarchem Laboratories New Jersey NJ
Eprosartan RC F ((Z) -4-({2-Butyl-5-[2-carboxy-3-(thiophen-2-yl) prop-1-enyl]-1H-imidazol-1-yl}methyl)benzoic acid(Z-Eprosartan))
Eprosartan RC F ((Z) -4-({2-Butyl-5-[2-carboxy-3-(thiophen-2-yl) prop-1-enyl]-1H-imidazol-1-yl}methyl)benzoic acid(Z-Eprosartan))
Sarchem Laboratories New Jersey NJ
Eprosartan related compound A
An impurity of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Synonyms: N-Descarboxyphenyl eprospartan; ((E)-3-(2-Butyl-1H-imidazol-5-yl)-2-(thiophen-2-ylmethyl)Acrylic Acid. Grade: > 95%. CAS No. 1169702-90-2. Molecular formula: C15H18N2O2S. Mole weight: 290.39.
Eprosartan Related Compound A
Eprosartan Related Compound A. Uses: For analytical and research use. CAS No. 1169702-90-2 (free base). Mole weight: 326.84. Catalog: ALP1169702902.
Eprosartan Related Compound B
Eprosartan Related Compound B. Uses: For analytical and research use. CAS No. 5928-51-8. Mole weight: 156.20. Catalog: AP5928518.
Eprosartan related compound C
An impurity of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Synonyms: (2-Thenyl)malonic acid, 2-(2-Thienylmethyl)propanedioic acid, 2-(Thiophen-2-ylmethyl)malonic acid. Grade: > 95%. CAS No. 4475-24-5. Molecular formula: C8H8O4S. Mole weight: 200.21.
Eprosartan Related Compound C
Eprosartan Related Compound C. Uses: For analytical and research use. CAS No. 4475-24-5. Mole weight: 200.21. Catalog: AP4475245.
Eprosartan Related Compound D
Eprosartan Related Compound D. Uses: For analytical and research use. CAS No. 6232-88-8. Mole weight: 215.04. Catalog: AP6232888.
Eprosartan Related Compound E
Eprosartan Related Compound E. Uses: For analytical and research use. CAS No. 3006-96-0. Mole weight: 152.15. Catalog: AP3006960.
Eprosartan related compound F
An impurity of Eprosartan. Eprosartan is an angiotensin II receptor antagonist used for the treatment of high blood pressure. Synonyms: (Z)-Eprosartan; (αZ)-α-[[2-Butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-2-thiophenepropanoic Acid. Grade: > 95%. CAS No. 148674-39-9. Molecular formula: C23H24N2O4S. Mole weight: 424.52.
Eprotirome
Eprotirome is a synthetic thyroid hormone mimetic as a thyroid hormone receptor beta agonists, lowers total and low-density lipoprotein cholesterol up to 40% without affecting high-density lipoprotein cholesterol levels and without deleterious side effects to the cardiovascular system. Uses: Thyroid hormone receptor beta agonists. Synonyms: KB-2115; KB 2115; KB2115; Eprotirome.3-[[3,5-dibromo-4-[4-hydroxy-3-(1-methylethyl)phenoxy]phenyl]amino-3-oxo-propanoic acid. Grade: ≥98%. CAS No. 355129-15-6. Molecular formula: C18H17Br2NO5. Mole weight: 487.14.
epsilon-caprolactone
epsilon-caprolactone. CAS No. 502-44-3. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
epsilon-Cyclodextrin is a modified cyclodextrin widely used in the biomedical industry. It facilitates the delivery of drugs by forming inclusion complexes, enhancing their solubility and stability. With its unique structure, epsilon-Cyclodextrin is applied in the research of various diseases, including cancer, diabetes and Alzheimer's. Synonyms: Cyclomaltodecaose; CD10. CAS No. 156510-98-4. Molecular formula: C60H100O50. Mole weight: 1621.41.
Epsilon-V1-2 (ε-V1-2), a PKCε-derived peptide, is a selective PKCε inhibitor. Epsilon-V1-2 inhibits the translocationof PKCε, but not α-, β-, and δPKC[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ε-V1-2; EAVSLKPT. CAS No. 182683-50-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P0154.
Epsom Salt
Epsom Salt (Magnesium Sulfate, Heptahydrate). Products can be packaged according to specific requirements and as per international standards for export shipments. Categories: magnesium sulfate heptahydrate; 10034-99-8; epsom salt.
Eptapirone, a triazine derivative, has been found to be a 5-HT1A receptor agonist and was once studied as an antidepressant agent. pKi: 8.33. Synonyms: F11440; F-11440; F 11440; Eptapirone; L0068; L-0068; L 0068; Eptapirone; Eptapirone [INN]; F 11440; 4-methyl-2-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-1,2,4-triazine-3,5-dione. Grade: 98%. CAS No. 179756-85-5. Molecular formula: C16H23N7O2.C4H4O4. Mole weight: 461.47.
Eptaplatin
A coordination compound for treatment of cervix cancer. Group: Biochemicals. Alternative Names: (SP-4-2)-[(4R, 5R)-2-(1-Methylethyl-1, 3-dioxolane4, 5-dimethanamine-kN4, kN5][propanedioato(2-)-kO1, kO3]platinum; Heptaplatin; cis-[ (4R, 5R)-4, 5-bis (aminomethyl)-2-isopropyl-1, 3-dioxolane] (malonate)platinum (II); SKI 2053R. Grades: Highly Purified. CAS No. 146665-77-2. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
EPTC-[d14]
EPTC-[d14] is the labelled analogue of EPTC, which is a pesticide. Synonyms: EPTC-d14 (di-n-propyl-d14); S-Ethyl-N,N-dipropylthiocarbamate-d14; S-Ethyl dipropylthiocarbamate-d14; EPTAM-d14; Torbin-d14; Eptam 6E-d14; Alirox-d14; Niptan-d14; Witox-d14. Grade: 99% atom D. CAS No. 1219794-88-3. Molecular formula: C9H5D14NOS. Mole weight: 203.40.
Eptifibatide
An arginin-glycin-aspartat-mimetic, reversibly binds to platelets to reduce the risk of cardiac ischemic events. Uses: Platelet aggregation inhibitors. Synonyms: L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1→6)-disulfide; Eftifibatide; Integrelin; Integrilin; Intrifiban; Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2(Mpr&Cys bridge); Deamino-cysteinyl-L-homoarginyl-glycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide (1->7)-disulfide; deamino-Cys-hArg-Gly-Asp-Trp-Pro-Cys-NH2 (Disulfide bridge: Cys1-Cys7). Grade: 98%. CAS No. 188627-80-7. Molecular formula: C35H49N11O9S2. Mole weight: 831.97.
Eptifibatide
Eptifibatide. Group: Biochemicals. Grades: Purified. CAS No. 188627-80-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Eptifibatide
Eptifibatide is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 188627-80-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0686.
Eptifibatide acetate, an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class, is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl residue. It reversibly binds to platelets to reduce the risk of cardiac ischemic events. Synonyms: L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1→6)-disulfide, acetate (1:x); deamino-Cys(1)-hArg-Gly-Asp-Trp-Pro-Cys(1)-NH2.xCH3CO2H; Deamino-cysteinyl-L-homoarginyl-glycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide (1->7)-disulfide acetate salt; Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2 (Mpr&Cys bridge) acetate. Grade: ≥95%. CAS No. 881997-86-0. Molecular formula: C35H49N11O9S2.xC2H4O2. Mole weight: 831.97 (free base).
Eptifibatide acetate
Eptifibatide acetate is a cyclic heptapeptide, acts as a competitive antagonist for the activated platelet glycoprotein IIb/IIIa receptor, with anti-platelet activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 881997-86-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B0686B.
Eptifibatide Dimer (Antiparallel)
An impurity of Eptifibatide. Eptifibatide is a glycoprotein IIb/IIIa inhibitor used primarily to prevent blood clots in patients with acute coronary syndromes (ACS) and during percutaneous coronary interventions (PCI). Synonyms: Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2(Mpr&Cys,Cys&Mpr bridge); Mpr-Har-GDWPC-NH2(Mpr&Cys,Cys&Mpr bridge); Eptifibatide (Dimer, unparallel); deamino-Cys-hArg-Gly-Asp-Trp-Pro-Cys-NH2.deamino-Cys-hArg-Gly-Asp-Trp-Pro-Cys-NH2 (Disulfide bridge: Cys1-Cys7', Cys7-Cys1'); L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, bimol. cyclic (1→6'),(6→1')-bis(disulfide); Eptifibatide Dimer; N6-Amidino-N2-(3-mercaptopropionyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic(1-6'),(6-1')-bis(disulfide); Eptifibatide Impurity 3. Grade: ≥95%. CAS No. 1505450-99-6. Molecular formula: C70H98N22O18S4. Mole weight: 1663.93.
Eptifibatide Dimer (parallel)
An impurity of Eptifibatide. Eptifibatide is a glycoprotein IIb/IIIa inhibitor used primarily to prevent blood clots in patients with acute coronary syndromes (ACS) and during percutaneous coronary interventions (PCI). Synonyms: Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2(Mpr&Mpr,Cys&Cys bridge); Mpr-Har-GDWPC-NH2(Mpr&Mpr,Cys&Cys bridge); Eptifibatide Dimer(parallel); deamino-Cys-hArg-Gly-Asp-Trp-Pro-Cys-NH2.deamino-Cys-hArg-Gly-Asp-Trp-Pro-Cys-NH2 (Disulfide bridge: Cys1-Cys1', Cys7-Cys7'); L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, bimol. cyclic (1→1'),(6→6')-bis(disulfide); Eptifibatide Dimer; N6-Amidino-N2-(3-mercaptopropionyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-Lprolyl-L-cysteinamide, cyclic(1-1'),(6-6')-bis(disulfide). Grade: ≥95%. CAS No. 1505451-00-2. Molecular formula: C70H98N22O18S4. Mole weight: 1663.93.
Eptifibatide Impurity 1
Eptifibatide Impurity 1 is an impurity of Eptifibatide, which is an antiplatelet drug of glycoprotein IIb/IIIa inhibitor. Molecular formula: C35H48N10O10S2. Mole weight: 832.95.
Eptifibatide Impurity 2
Eptifibatide Impurity 2 is an impurity of Eptifibatide, which is an antiplatelet drug of glycoprotein IIb/IIIa inhibitor. Molecular formula: C35H51N11O10S2. Mole weight: 849.98.
Eptifibatide Impurity 3
Eptifibatide Impurity 3 is an impurity of Eptifibatide, which is an antiplatelet drug of glycoprotein IIb/IIIa inhibitor. Molecular formula: C70H98N22O18S4. Mole weight: 1663.93.
Eptifibatide monoacetate
Eptifibatide monoacetate, an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class, is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl residue. It reversibly binds to platelets to reduce the risk of cardiac ischemic events. Synonyms: L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1→6)-disulfide, acetate (1:1); deamino-Cys(1)-hArg-Gly-Asp-Trp-Pro-Cys(1)-NH2.CH3CO2H; Deamino-cysteinyl-L-homoarginyl-glycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide (1->7)-disulfide acetic acid; Eptifibatide acetate; Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2 (Mpr&Cys bridge) acetate. Grade: ≥95%. CAS No. 1248559-53-6. Molecular formula: C35H49N11O9S2.C2H4O2. Mole weight: 892.02.
Eptifibatide Trisulfide
An impurity of Eptifibatide. Eptifibatide is a glycoprotein IIb/IIIa inhibitor used primarily to prevent blood clots in patients with acute coronary syndromes (ACS) and during percutaneous coronary interventions (PCI). Synonyms: Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2(Mpr&Cys Trisulfidebridge); Mpr-Har-GDWPC-NH2(Mpr&Cys Trisulfidebridge); deamino-Cys-hArg-Gly-Asp-Trp-Pro-Cys-NH2 (Trisulfide bridge: Cys1-Cys7); Deamino-cysteinyl-L-homoarginyl-glycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide (1->7)-trisulfide; Trisulphide Eptifibatide. Grade: ≥95%. Molecular formula: C35H49N11O9S3. Mole weight: 864.03.
Eptinezumab
Eptinezumab is a humanized monoclonal antibody targeting calcitonin gene-related peptide (CGRP). Eptinezumab has been used for the preventive treatment of migraine in adults. Synonyms: Vyepti. CAS No. 1644539-04-7.
Eptinezumab
Eptinezumab (ALD-403) is a human monoclonal antibody targeting the α and β subtypes of human calcitonin gene-related peptide (CGRP). Eptinezumab binds to the CGRP ligand and blocks its binding to endogenous CGRP receptors, thereby inhibiting receptor activation. Eptinezumab can be used in research related to migraine[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALD-403. CAS No. 1644539-04-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99017.
Epyrifenacil
Epyrifenacil is a protoporphyrinogen oxidase (PPO) inhibiting herbicide, potently targeting the PPO2 isoform from weeds such as Amaranthus palmeri with an IC50 of 0.637 nM. Epyrifenacil also inhibits liver mitochondrial PPO across species, with IC50 values of 2.2 nM (mouse), 2.6 nM (rat), 12.1 nM (rabbit), 7.6 nM (dog), and 10.2 nM (human). Epyrifenacil induces liver tumor development in mice. Epyrifenacil can be used for weed control, and also used as a tool compound in toxicological research to study the mechanism of PPO inhibition, chemical-induced hepatotoxicity, and the mode of action of non-genotoxic carcinogens in rodents[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 353292-31-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-139838.
EPZ004777
EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM in a cell-free assay and demonstrates >1,200-fold selectivity for DOT1L over all other tested PMTs. EPZ004777 induces apoptosis. Group: Inhibitors. CAS No. 1338466-77-5. Pack Sizes: 5mg. Product ID: S7353. Formula: C28H41N7O4. Smiles: CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)CC2C(C(C(O2)N3C=CC4=C(N=CN=C43)N)O)O. Storage Conditions: 2 years -80 in solvent.
United States; Europe
EPZ004777
EPZ004777 is an effective and selective DOT1L inhibitor, with IC50 being 0.4 nM. EPZ004777 reduces the levels of H3K79me2 and H3K79me1, significantly down-regulating the expression of HOXA9 and MEIS1. EPZ004777 selectively inhibits the proliferation of MLL rearrangement cells and promotes the differentiation and subsequent apoptosis (apoptosis) of leukemia cells. EPZ004777 can be used for the study of leukemia[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1338466-77-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-15227.
EPZ004777
EPZ004777 is a potent, selective inhibitor of DOT1L. Treatment of mixed lineage leukemia (MLL) cells with EPZ004777 selectively inhibits H3K79 methylation and blocks expression of leukemogenic genes. Exposure of leukemic cells to EPZ004777 results in selective killing of those cells bearing the MLL gene translocation, with little effect on non-MLL-translocated cells. Finally, in vivo administration of EPZ004777 leads to extension of survival in a mouse MLL xenograft model. These results provide compelling support for DOT1L inhibition as a basis for targeted therapeutics against MLL. Uses: Reprogramming. Synonyms: EPZ004777; EPZ 004777; EPZ-004777. Grade: 0.98. CAS No. 1338466-77-5. Molecular formula: C28H41N7O4. Mole weight: 539.681.
EPZ004777 hydrochloride
EPZ004777 selectively inhibits cellular H3K79 methylation and inhibits expression of key MLL fusion target genes. Following DOT1L inhibition, EPZ004777 selectively inhibits proliferation of MLL-Rearranged cell lines and MLL-AF9-transformed murine hematopoietic cells. In addition, EPZ004777 also induces differentiation and apoptosis in MLL-rearranged cells. EPZ004777 selectively inhibits proliferation of MLL-AF10 and CALM-AF10-transformed murine bone marrow cells. DOT1L inhibition by EPZ004777 results in significantly decreased proliferation, decreased expression of MLL-AF6 target genes, and cell cycle arrest of MLL-AF6-transformed cells. Synonyms: EPZ 004777 hydrochloride; EPZ-004777 hydrochloride; EPZ004777 hydrochloride. Grade: >98%. CAS No. 1380316-03-9. Molecular formula: C28H42ClN7O4. Mole weight: 576.13.
EPZ004777 hydrochloride
EPZ004777 hydrochloride is an effective and selective DOT1L inhibitor, with IC50 being 0.4 nM. EPZ004777 hydrochloride reduces the levels of H3K79me2 and H3K79me1, significantly down-regulating the expression of HOXA9 and MEIS1. EPZ004777 hydrochloride selectively inhibits the proliferation of MLL rearrangement cells and promotes the differentiation and subsequent apoptosis (apoptosis) of leukemia cells. EPZ004777 hydrochloride can be used for the study of leukemia[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1380316-03-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15227A.