A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
FR-193262 is a designed prostacyclin mimetic without PG skeleton which exhibits potent PGI2 agonistic activity with good selectivity for IP receptor and bioavailability. Synonyms: FR-193262; FR 193262; FR193262; sodium;2-[[(5R)-5-[(2R)-2-(4,5-diphenyl-1,3-oxazol-2-yl)pyrrolidin-1-yl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetate; FR-193262; 187992-22-9(FR-193262); 314289-63-9 (FR-193262 Free Base). Grades: >98%. CAS No. 187992-22-9. Molecular formula: C31H29N2NaO4. Mole weight: 516.56.
FR-193262 Free base
A bio-active organic chemical. Uses: A bio-active organic chemical. Synonyms: FR-193262; FR 193262; FR193262; 2-[[(5R)-5-[(2R)-2-(4,5-diphenyl-1,3-oxazol-2-yl)pyrrolidin-1-yl]-5,6,7,8-tetrahydronaphthalen-1-yl]oxy]acetic acid. Grades: ≥98%. CAS No. 314289-63-9. Molecular formula: C31H30N2O4. Mole weight: 494.59.
FR-193879
FR-193879, a cephem derivative, is an efficacious anti-Helicobacter pylori cephalosporin. Synonyms: (6R,7R)-3-[[4-(2-amino-2-oxoethyl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-7-[(2-phenylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; FR-193879; FR193879; FR 193879. Grades: >98%. CAS No. 194928-82-0. Molecular formula: C20H18N4O5S3. Mole weight: 490.58.
FR-194921 is a potent, selective and orally active antagonist for central adenosine A1 receptors that displays high affinity and selectivity for the adenosine A1 receptor (Ki= 2.9 nM) and did not show species differences in binding affinity. Synonyms: 2-(1-methylpiperidin-4-yl)-6-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)pyridazin-3-one; FR-194921; FR 194921; FR194921; 2-(1-methyl-4-piperidinyl)-6-(2-phenylpyrazolo(1,5-a)pyridin-3-yl)-3(2H)-pyridazinone. Grades: >98%. CAS No. 202646-80-8. Molecular formula: C23H23N5O. Mole weight: 385.46.
FR-198248
FR-198248, a new type of hydroxyl benzaldehyde compound, was isolated from the cultured broth of a fungal strain identified as Aspergillus terreus from morphological characteristics. FR-198248 exhibited anti-influenza virus activity in Madin-Darby canine kidney (MDCK) cells in vitro. Synonyms: fr198248; 1,3-Dihydro-4-methyl-1,5,6,7-isobenzofurantetraol. Grades: >98%. CAS No. 197316-54-4. Molecular formula: C9H10O5. Mole weight: 198.17.
FR-202306
FR-202306 is a synthetic peptide deformylase (PDF) inhibitor. Uses: Peptide deformylase (pdf) inhibitor. Synonyms: FR-202306; FR 202306; FR202306. 3-methoxy-7-methyl-1,3-dihydro-2-benzofuran-4,5,6-triol. Grades: ≥98%. CAS No. 342785-41-5. Molecular formula: C10H12O5. Mole weight: 212.20.
FR-217840
FR-217840 is a matrix metalloproteinase inhibitor. It can suppress joint destruction. FR217840 may have potential as a novel anti-rheumatic drug. Uses: Anti-rheumatic agent. Synonyms: FR-217840; FR217840; FR 217840. (2S)-1-((5-(4-fluorophenyl)-2-thienyl)sulfonyl)-N-hydroxy-4-(methylsulfonyl)-2-Piperazinecarboxamide. Grades: 98%. CAS No. 848444-16-6. Molecular formula: C16H18FN3O6S3. Mole weight: 463.52.
FR-218944
FR-218944 is a vasopressin antagonist compound. Synonyms: methanesulfonic acid;2-methoxy-N-(2-methyl-1H-benzimidazol-4-yl)-4-(2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)benzamide; FR-218944; FR 218944; FR218944. Grades: >98%. CAS No. 233264-02-3. Molecular formula: C28H30N4O6S. Mole weight: 550.63.
FR-221647
FR-221647 is a non-nucleoside adenosine deaminase inhibitor. Synonyms: 1-(1-hydroxy-4-phenylbutan-2-yl)imidazole-4-carboxamide; FR-221647; FR 221647; FR221647. Grades: >98%. CAS No. 256461-28-6. Molecular formula: C14H17N3O2. Mole weight: 259.3.
FR225659
FR225659 is originally isolated from Helicomyces sp. No. 19353. It can suppress the gluconeogenesis induced by Glucagon in Primary hepatocytes of rats. Molecular formula: C36H42ClN7O8. Mole weight: 736.21.
FR-229934
FR-229934 is a Type 5 cyclic nucleotide phosphodiesterase inhibitor. In Feb 2008, preclinical for Erectile dysfunction in Japan was discontinued. Uses: Erectile dysfunction. Synonyms: FR-229934; FR229934; FR 229934. 1-((3,4-dichlorophenyl)methyl)-2-methyl-N-(pentylsulfonyl)-1H-Benzimidazole-6-carboxamide. Grades: 98%. CAS No. 799841-02-4. Molecular formula: C21H23Cl2N3O3S. Mole weight: 468.40.
FR-234938
FR-234938, with anti-inflammatory property, is a non-nucleoside recombinant human adenosine deaminase enzyme inhibitor. Synonyms: 1-[(3R,4S)-4-hydroxy-1-naphthalen-1-ylpentan-3-yl]imidazole-4-carboxamide; FR-234938; FR 234938; FR234938. Grades: >98%. CAS No. 256461-79-7. Molecular formula: C19H21N3O2. Mole weight: 323.39.
FR-235222
FR-235222 is an immunosuppressive substance that inhibits mammalian histone deacetylase (HDAC). It is produced by the strain of Acremonium sp. No. 27082. Synonyms: FR 235222; FR235222. Molecular formula: C30H44N4O6. Mole weight: 556.69.
FR236913
FR236913 is a compoundused in studying chronic lymphocytic leukemia (CLL) and other hematologic malignancies. This targeted therapy inhibits Bruton's tyrosine kinase (BTK) is a key enzyme in the B-cell receptor signaling pathway. By disrupting abnormal B-cell signaling, FR236913 helps control the progression of CLL. Synonyms: 1-[(2R)-4-{6-[(Benzylcarbamoyl)amino]-1H-indol-1-yl}-1-hydroxybutan-2-yl]-1H-imidazole-4-carboxamide. Molecular formula: C24H26N6O3. Mole weight: 446.5.
FR 236924
FR 236924. Group: Biochemicals. Grades: Purified. CAS No. 28399-31-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
FR 236924
FR 236924 is a selective PKCε activator with > 7-fold selectivity over other PKC isozymes. FR 236924 promotes glutamate release via presynaptic α7 nicotinic receptors on glutamatergic terminals in vitro and enhances cognition in vivo. It has the potential for the treatment of Alzheimer disease. Synonyms: FR 236924; FR236924; FR-236924; Dcp-LA; 2-[ (2-Pentylcyclopropyl) methyl]cyclopropaneoctanoic acid. Grades: ≥99% by HPLC. CAS No. 28399-31-7. Molecular formula: C20H36O2. Mole weight: 308.5.
FR252384 is novel potent antagonists of human neuropeptide Y-Y5 receptor (IC50= 2.3 nM). Synonyms: FR252384; FR 252384; FR-252384; 9-methyl-2-pyridin-3-yl-3,4,5,6-tetrahydrobenzo[2,3]cyclohepta[2,4-b]imidazole; Benzo[3,4]cyclohept[1,2-d]imidazole, 1,4,5,6-tetrahydro-9-methyl-2-(3-pyridinyl)-. CAS No. 447405-11-0. Molecular formula: C18H17N3. Mole weight: 275.35.
FR 252921
FR 252921 is produced by the strain of Pseudomonas fluorenscens No. 408813. It shows immunosuppressive effect in mice in vivo and in vitro, and has synergistic effect with FK-506. Molecular formula: C29H44N2O5. Mole weight: 500.67.
FR-252922
FR-252922 is produced by the strain of Pseudomonas fluorenscens No. 408813. It shows immunosuppressive effect in mice in vivo and in vitro, and has synergistic effect with FK-506. Molecular formula: C31H48N2O5. Mole weight: 528.72.
FR-29038
It is originally isolated from Nocardia uniformis subsp. tsuyamanensis. FR-29038 has anti-Bacillus, Escherichia, Klebsiella, Pseudomonas, Salmonella, Shigella and other family bacteria activities. Synonyms: Antibiotic FR 29038; BRN 3578863; O-{4-[1-Amino-2-({1-[carboxy(4-hydroxyphenyl)methyl]-2-oxoazetidin-3-yl}imino)-2-hydroxyethyl]phenyl}homoserine. CAS No. 59511-12-5. Molecular formula: C23H26N4O8. Mole weight: 486.47.
FR295389 free base
FR295389 free base is a new cephalosporin. It shows effective in vitro antibacterial activity against metallo-beta-lactamase (MBL)-producers. Uses: Fr295389 free base has effective antibacterial activity. Synonyms: FR-295389 free base; FR 295389 free base; FR295389 free base; (6R,7R)-3-[[7-[3-aminopropyl(carbamimidoyl)amino]-2,3-dihydroimidazo[1,2-b]pyrazol-5-yl]methyl]-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Grades: >98 %. CAS No. 1019207-71-6. Molecular formula: C25H33N13O7S2. Mole weight: 691.74.
FR295389 sulfuric acid
FR295389 sulfuric acid is the sulfate form of FR295389, which is a new cephalosporin. It has effective in vitro antibacterial activity against metallo-beta-lactamase (MBL)-producers. Uses: Fr295389 sulfuric acid has effective antibacterial activity. Synonyms: FR-295389 sulfuric acid; FR 295389 sulfuric acid; FR295389 sulfuric acid; (6R,7R)-3-[[7-[3-aminopropyl(carbamimidoyl)amino]-2,3-dihydroimidazo[1,2-b]pyrazol-5-yl]methyl]-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sulfuric acid. Grades: >98 %. CAS No. 1019207-72-7. Molecular formula: C25H35N13O11S3. Mole weight: 789.81.
FR 32863
FR 32863 is produced by the strain of Streptomyces lavendulae 8006. FR 32863 has anti-gram-positive and anti-gram-negative activities. Synonyms: Antibiotic FR 32863; Antibiotic FR 900136; BRN 2092108; FR-32863; (E)-(3-(Formylhydroxyamino)-1-propenyl)phosphonic acid. CAS No. 66508-88-1. Molecular formula: C4H8NO5P. Mole weight: 181.08.
FR-33289
FR-33289 is produced by the strain of Streptomyces rubellomurinus subsp. indigoferus 24. FR-33289 has anti-gram-positive and anti-gram-negative activities. Synonyms: Antibiotic FR 33289; (R)-(3-(Acetylhydroxyamino)-2-hydroxypropyl)phosphonic acid. CAS No. 73240-15-0. Molecular formula: C5H12NO6P. Mole weight: 213.13.
FR-62765
FR-62765, a derivative of WF-3681, is a novel aldose reductase inhibitor. It might be a useful drug for diabetic neuropathy. Uses: Fr-62765 might be a useful drug for diabetic neuropathy. Synonyms: FR 62765; FR-62765; FR62765. 2-Furanpropanoic acid, 2,5-dihydro-4-methoxy-5-oxo-3-phenyl-, ethyl ester;FR62765;2,5-Dihydro-4-methoxy-5-oxo-3-phenylfuran-2-propanoic acid ethyl ester;Ethyl 2,5-dihydro-4-methoxy-5-oxo-3-phenyl-2-furanpropanoate;Ethyl 3-(4-methoxy-5-oxo-3-phenyl-2H-furan-2-yl)propanoate. Grades: >98 %. CAS No. 105346-34-7. Molecular formula: C16H18O5. Mole weight: 290.31.
FR-64822
FR-64822 is a novel non-opioid antinociceptive compound. It has antinociceptive activities in a variety of assays in mice and rats. It also has a strong antinociceptive activity in the acetic acid writhing test. Uses: Fr-64822 has antinociceptive activities. Synonyms: FR 64822; FR64822; FR-64822. N-(4-Pyridylcarbamoyl)amino 1,2,3,6-tetrahydropyridine;1-(3,6-dihydro-2H-pyridin-1-yl)-3-pyridin-4-ylurea;FR64822. Grades: >98 %. CAS No. 102671-35-2. Molecular formula: C11H14N4O. Mole weight: 218.26.
FR 65814
FR 65814 is originally isolated from Penicillum jensenii F-2883. It has a strong immunosuppressive effect, and the IC50 of inhibiting mixed lymphocyte reaction (MLR) in mice is 34 nmol/L. Synonyms: 4-(2-Methyl-3-(3-methyl-2-butenyl)oxiranyl)-1-oxaspiro(2.5)octane-5,6-diol. CAS No. 103470-60-6. Molecular formula: C15H24O4. Mole weight: 268.35.
FR 66979
FR 66979 is produced by the strain of Streptomyces sandaensis No. 6897. It has inhibitory activity against tumor cells, including leukemia P388 cells and melanoma B16 cells. Synonyms: [7,9-Dihydroxy-5-(hydroxymethyl)-1,1a,2,8,9,9a-hexahydro-3,9-epoxyazireno[2,3-c][1]benzazocin-8-yl]methyl hydrogen carbonimidate. Grades: 97%. CAS No. 102409-60-9. Molecular formula: C14H17N3O6. Mole weight: 323.30.
FR 75513
FR 75513 is a 1,1'-biphenyl-2,6-dicarboxylic acid diester compound with inhibitory activity on guinea-pig detrusor muscle contraction at electrical field stimulation in vitro. IC 50 value is 3.3 x 10(-6) g/ml. Synonyms: FR 75513; FR75513; FR-75513. 3-O-methyl 1-O-propan-2-yl 4-hydroxy-6-methyl-2-(2-nitrophenyl)benzene-1,3-dicarboxylate. Grades: 98%. CAS No. 127975-78-4. Molecular formula: C19H19NO7. Mole weight: 373.36.
FR 76830
This molecular is developed as a novel bradycardiac agent through organic synthesis. Uses: Bradycardiac agent. Synonyms: FR 76830; FR-76830; FR76830. 2-methyl-N-(4-morpholinylethyl)-4-(3-nitrophenyl)-6-phenyl- 3-Pyridinecarboxamide. Grades: 98%. CAS No. 113243-75-7. Molecular formula: C25H26N4O4. Mole weight: 446.5.
FR-78844
FR-78844 is used as a bone resorption antagonist. Uses: Fr-78844 is used as a bone resorption antagonist. Synonyms: FR 78844; FR78844; FR-78844; Disodium phenylthiocarbamoyl methyl enediphosphonate; (2- (Phenylamino) -2-thioxoethylidene) bisphosphonic acid disodium salt;Disodium [2-anilino-1-[hydroxy(oxido)phosphoryl]-2-sulfanylideneethyl]-hydroxyphosphinate; FR78844; Phosphonic acid, (2-(phenylamino)-2-thioxoethylidene)bis-, disodium salt. Grades: >98%. CAS No. 112856-39-0. Molecular formula: C8H9NNa2O6P2S. Mole weight: 355.15.
FR-900098
FR-900098 is produced by the strain of Streptomyces rubellomurinus subsp. indigoferus 24. FR-900098 has anti-gram-positive and anti-gram-negative activities. Synonyms: Antibiotic FR-900098; FR 900098; BRN 2096083; 3-(N-acetyl-N-hydroxy)aminopropylphosphonic acid. Grades: >98%. CAS No. 66508-32-5. Molecular formula: C5H12NO5P. Mole weight: 197.13.
Fr 900098 monosodium salt
Fr 900098 monosodium salt. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3-[ethanoyl(Hydroxy)amino]propylphosphonic Acid; {3-[acetyl(benzyloxy)amino]propyl}phosphonic acid; {3-[acetyl(hydroxy)amino]propyl}phosphonic acid; Phosphonic acid,(3-(acetylhydroxyamino)propyl); 3-(N-Acetyl-N-hydroxyamino)-propyl-phosphonsaeure; [3-(N-a. Product Category: Heterocyclic Organic Compound. CAS No. 66508-32-5. Molecular formula: C5H12NO5P. Mole weight: 197.126241 [g/mol]. Purity: 0.96. IUPACName: 3-[acetyl(hydroxy)amino]propylphosphonic acid. Canonical SMILES: CC(=O)N(CCCP(=O)(O)O)O. Density: 1.492g/cm³. Product ID: ACM66508325. Alfa Chemistry ISO 9001:2015 Certified. Categories: 73226-73-0.
The antibiotics Fosmidomycin and FR900098 are members of a unique class of phosphonic acid natural products that inhibit the nonmevalonate pathway for isoprenoid biosynthesis. Both are potent antibacterial and antimalarial compounds. Group: Biochemicals. Alternative Names: P-[3- (Acetylhydroxyamino) propyl]phosphonic Acid Sodium Salt. Grades: Highly Purified. CAS No. 73226-73-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
FR900098 sodium salt
FR900098 is a derivative of fosmidomycin that displays antimalarial activity. FR900098 is an inhibitor of DOXP reductoisomerase, a key enzyme in the non-mevalonate pathway of isoprenoid biosynthesis. Synonyms: (3-(Acetylhydroxyamino)propyl)-phosphonic acid, monosodium salt; BRN 2096083; P-[3-(Acetylhydroxyamino)propyl]-phosphonic acid, monosodium salt. Grades: ≥95%. CAS No. 73226-73-0. Molecular formula: C5H11NO5P·Na. Mole weight: 219.1.
FR 900109
It is produced by the strain of Streptomyces prunicolor. FR 900109 has anti-gram-positive bacteria activity. Synonyms: Antibiotic FR900109; FR900109. CAS No. 83512-61-2. Molecular formula: C27H32O9. Mole weight: 500.54.
FR 900130
FR 900130, isolated from Streptomyces catenulae, is an antibiotic easily to decompose. It has anti-gram-positive and anti-gram-negative activities, and has a synergistic effect with D-cycloserine. Synonyms: L-2-amino-3-butynoic acid; Antibiotic FR 900130; (S)-2-Amino-3-butynoic acid. Grades: >95%. CAS No. 73537-09-4. Molecular formula: C4H5NO2. Mole weight: 99.09.
FR 900137
FR 900137 is produced by the strain of Streptomyces unzenensis 2050. It has a broad spectrum of antibacterial activity and has a strong effect on Pseudomonas aeruginosa ?. Synonyms: Antibiotic FR 900137; L-Leucine, 2-(hydroxymethoxyphosphinyl)-2-methylhydrazide; 2-Amino-N-[hydroxy(methoxy)phosphoryl]-N,4-dimethylpentanehydrazonic acid. CAS No. 73706-58-8. Molecular formula: C8H20N3O4P. Mole weight: 253.24.
FR-900148
It is originally isolated from Streptomyces xanthocidicus 301. FR-900148 can inhibit gram-positive and gram-negative bacteria, but has no effect on pseudomonas aeruginosa. CAS No. 73706-57-7. Molecular formula: C10H15ClN2O5. Mole weight: 278.69.
FR900359
FR900359 is a depsipeptide selective inhibitor of G?q/11/14 in mammalia, can inhibits ERK pathway. FR900359 suppresses the proliferation of melanoma cells and decreases of blood pressure. FR900359 also protected against airway hyperreactivity in murine models of allergen sensitization in Ovalbumins(HY-W250978)-induced sensitization model of asthma. FR900359 can be used for cancer and cardiovascular disease research[1][2][3][4]. Uses: Scientific research. Group: Natural products. CAS No. 107530-18-7. Pack Sizes: 250 ?g ; 500 ?g. Product ID: HY-117037.
FR 900403
FR 900403 is a nucleoside antibiotic originally isolated from Kernia sp. F-19849. It had anti-Candida activity, and the MIC against Candida albicans FP663 was 0.4 μg/mL. Synonyms: FR900403; beta-D-Ribofuranuronic acid, 3-((2-amino-3-methyl-1-oxopentyl)amino)-1-(6-amino-9H-purin-9-yl)-1,3-dideoxy-. CAS No. 131206-83-2. Molecular formula: C16H23N7O5. Mole weight: 393.40.
FR 900482
FR 900482 is produced by the strain of Streptomyces sandaensis No. 6897. It is highly sensitive to Bacillus stearothermophilus var. calidolactis C 953 and has anti-P388, B16, EL4, FM3A, L1210, BHK-21 and other cell activities. Synonyms: Antibiotic FR 900482; BRN 4886722; (5-Formyl-7,9-dihydroxy-1,1a,2,8,9,9a-hexahydro-3,9-epoxyazireno[2,3-c][1]benzazocin-8-yl)methyl hydrogen carbonimidate. CAS No. 102363-08-6. Molecular formula: C14H15N3O6. Mole weight: 321.28.
FR-900490
FR-900490 is a new type of immunoactive substance isolated from Disocia sp. F-11809. It is effective in reversing the damage to bone marrow caused by mitomycin C. Uses: Fr-900490 is effective in reversing the damage to bone marrow caused by mitomycin c. Synonyms: FR 900490; FR900490; BMY 28700; BMY28700; BMY-28700; (2S,3R)-2-[(L-Asparaginyl)amino]-3-[[(S)-1-carboxy-2-(1H-imidazol-4-yl)ethyl]amino]butanoic acid. Grades: >98%. CAS No. 105424-59-7. Molecular formula: C14H22N6O6. Mole weight: 370.36.
FR 900523
FR 900523, isolated from Streptomyces, suppresses immune response in vitro with IC50 of 1.6 nM for mouse mixed lymphocyte. CAS No. 104987-09-9. Molecular formula: C42H67NO12. Mole weight: 777.98.
FR 900525
FR 900525 is a metabolite produced by the strain of Streptomyces tsukubaensis No. 9993. It has antifungal activity. Synonyms: BRN 4225908; FR-900525. CAS No. 104987-10-2. Molecular formula: C43H67NO12. Mole weight: 789.99.
FR 901235
This active molecular is an immunoactive substance produced by Paecilomyces carneus F-4882, an imperfect fungus. FR-901235 can lead the mitogen-induced lymphocyte proliferation to go back to a normal level after being suppressed by addition of immunosuppressive factor. Synonyms: FR-901235; (-)-2,4,9-Trihydroxy-6-methoxy-7-methyl-2-(2-oxopropyl)-1H-phenalene-1,3(2H)-dione. Grades: 95%. CAS No. 124190-19-8. Molecular formula: C18H16O7. Mole weight: 344.31.
FR 901379
FR 901379 is an impurity of Micafungin, a lipopeptide compound that acts as an antifungal agent with activity against Aspergillus and Candida species. FR901379 is an echinocandin-like antifungal lipopeptide with inhibitory activity against C. albicans, C. krusei, C. tropicalis, C. utilis, A. fumigatus, and A. niger fungi (IC50s = <0.003-1.9 μg/ml). FR 901379 has a protective effect against C. albicans infection in mice (ED50 = 1.1 mg/kg). It also reduces the number of lung cysts and trophozoites in a mouse model of Plasmodium carinii infection. Synonyms: 1-[(4R,5R)-4,5-Dihydroxy-N2-(1-oxohexadecyl)-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; (2α,3β,4β)-(4R,5R)-4,5-Dihydroxy-N2-(1-oxohexadecyl)-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonyl-3-hydroxy-L-glutaminyl-3-hydroxy-4-methyl-L-Proline Cyclic (6?1)-Peptide; 1H-Dipyrrolo[2, 1-c:2', 1'-l][1, 4, 7, 10, 13, 16]hexaazacycloheneicosine Cyclic Peptide Deriv. Grades: ≥90%. CAS No. 144371-88-0. Molecular formula: C51H82N8O21S. Mole weight: 1175.30.
It is originally isolated from Flexibacter sp. No. 758. FR-901451 had inhibitory activity against HLE with ID50 of 2.3 X 10-7 mol/L. And it also has inhibitory effects on PPE, chymosin and proteinase. Molecular formula: C61H81N13O18. Mole weight: 1284.37.
FR901459
FR901459, a product of the fungus Stachybotrys chartarum No. 19392, is a derivative of cyclosporin A (CsA) and a powerful immunosuppressant that binds cyclophilin. Its immunosuppressive effect was lower than that of cyclostatin A. CAS No. 155144-72-2. Molecular formula: C62H111N11O13. Mole weight: 1218.61.
FR-901463
FR-901463 is a potent cell cycle inhibitor isolated from Pseudomonas sp. No.2663. It exhibits potent antitumor activities against tumor cell lines via binding to the spliceosome and modulating pre-mRNA splicing. Synonyms: FR 901463; FR901463; WB 2663A. CAS No. 146478-74-2. Molecular formula: C27H42ClNO8. Mole weight: 544.1.
FR901464
FR901464 is a potent spliceosome inhibitor with prominent anti-tumor and anti-cancer effects[1]. Uses: Scientific research. Group: Natural products. CAS No. 146478-72-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16212.
FR 901464
FR901464 is a potent spliceosome inhibitor and a potential agent for colorectal cancer in combination therapy. Uses: Designed for use in research and industrial production. Additional or Alternative Names: FR 901464; FR-901464; FR901464; WB 2663B. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 146478-72-0. Molecular formula: C27H41NO8. Mole weight: 507.62. Purity: >98%. IUPACName: (2S,E)-5-(((2R,5S,6S)-6-((2E,4E)-5-((4R,5R,7S)-4,7-dihydroxy-7-methyl-1,6-dioxaspiro[2.5]octan-5-yl)-3-methylpenta-2,4-dien-1-yl)-2,5-dimethyltetrahydro-2H-pyran-3-yl)amino)-5-oxopent-3-en-2-yl acetate. Canonical SMILES: C[C@H]1CC([C@H](O[C@H]1C/C=C(\C)/C=C/[C@@H]2[C@H](C3(C[C@@](O2)(C)O)CO3)O)C)NC(=O)/C=C/[C@H](C)OC(=O)C. Product ID: ACM146478720. Alfa Chemistry ISO 9001:2015 Certified.
FR-901465
FR-901465 is a potent cell cycle inhibitor isolated from Pseudomonas sp. No.2663. It exhibits potent antitumor activities against tumor cell lines via binding to the spliceosome and modulating pre-mRNA splicing. Synonyms: FR 901465; FR901465; WB 2663C. CAS No. 146478-73-1. Molecular formula: C27H41NO9. Mole weight: 523.6.
FR901469
FR901469 is an antifungal antibiotic produced by fungal sp. No. 11243. It inhibits the activity of 1, 3-β-glucan synthase, and has strong anti-Candida albicans and Aspergillus fumigatus activity in vitro and in vivo. Synonyms: FR-901469; Lipopeptidolactone FR901469. Molecular formula: C71H116N14O23. Mole weight: 1533.76.
FR901483
FR901483 is originally isolated from Cladotryum sp. No. 11231. It has a strong immunosuppressive effect. Molecular formula: C20H31N2O6P. Mole weight: 426.44.
FR901512
FR901512, a new specific inhibitor of HMG-CoA reductase, is isolated from the culture of an agonomycetous fungus No. 14919. FR901512 inhibits cholesterol synthesis from [14C] acetate in Hep G2 cells. Synonyms: 6-Heptenoic acid, 7-[(6R,8S)-8-(acetyloxy)-5,6,7,8-tetrahydro-2,6-dimethyl-1-naphthalenyl]-3,5-dihydroxy-, (3R,5S,6E)-; (3R,5S,E)-7-((6R,8S)-8-acetoxy-2,6-dimethyl-5,6,7,8-tetrahydronaphthalen-1-yl)-3,5-dihydroxyhept-6-enoic acid. CAS No. 151606-25-6. Molecular formula: C21H28O6. Mole weight: 376.44.
FR 901537
FR-901537, a naphthothiazin compound, has been found to be an aromatase inhibitor that could be used as a cytostatic antibiotic and was once studied in breast cancer. Synonyms: FR-901537; FR901537; (R)-N-(3-((2-((2,3-Dihydro-6-hydroxy-2-oxo-1H-naphtho(2,1-b)(1,4)thiazin-5-yl)thio)ethyl)amino)-3-oxopropyl)-2,4-dihydroxy-3,3-dimethylbutanamide. Grades: 98%. CAS No. 161162-21-6. Molecular formula: C23H29N3O6S2. Mole weight: 507.62.
FR-A 19
FR-A 19 is a Histamine H2 receptor agonist with potent anti-allergic properties. It can inhibit IgE-mediated human basophil histamine release in a nanomolar range. Uses: Anti-allergic agent. Synonyms: FR-A 19; FR-A-19; FRA19; N,N-bis(3-(4-fluorophenyl)propyl)-N'-(3-(1H-imidazol-4-yl)propyl)-Guanidine trihydrochloride. Grades: 98%. CAS No. 141099-46-9. Molecular formula: C25H34Cl3F2N5. Mole weight: 548.93.
Fractalkine, Chemokine Domain from mouse
>97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder. Group: Fluorescence/luminescence spectroscopy.
Fractalkine, Chemokine Domain human
?97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder. Group: Fluorescence/luminescence spectroscopy.
Fractalkine, Extracellular Domain human
?97% (SDS-PAGE), recombinant, expressed in NSO cells, suitable for cell culture, lyophilized powder. Group: Fluorescence/luminescence spectroscopy.
Fractionated Coconut Oil MCT
Fractionated Coconut Oil is a medium chain triglyceride of superior quality, evidenced by its bland taste, low odor & color. It is insoluble in water but soluble in IPA, Mineral & Vegetable Oils. You will see it in products like CBD, used as a dilute oil. Uses: Flavors, Fragrances, Dispersant. Alternative Names: Caprylic/Capric Triglyceride, MCT. Grades: Food. CAS No. 65381-09-01,73398-61-5. Pack Sizes: 5 Gal Pail, 55 Gal Drums.
USA
Fragilomycin A
Fragilomycin A is produced by the strain of Streptosporangium fragilis SK & F-BC2496. It has anti-gram-negative bacteria and anaerobic bacteria activity. Molecular formula: C54H82N2O26. Mole weight: 1175.22.
fragilysin
Thought to be a cause of diarrhoea in animals and humans. Hydrolyses extracellular matrix proteins, and disrupts tight junctions of intestinal epithelial cells. Also degrades intracellular, cytoskeletal proteins actin, myosin and others. In peptidase family M10 (interstitial collagenase family). Group: Enzymes. Synonyms: Bacteroides fragilis (entero)toxin. Enzyme Commission Number: EC 3.4.24.74. CAS No. 188596-63-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4358; fragilysin; EC 3.4.24.74; 188596-63-6; Bacteroides fragilis (entero)toxin. Cat No: EXWM-4358.
Fragment (27-32)-Calcitonin
Fragment (27-32)-Calcitonin is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: Thr-Gly-Ser-Gly-Thr-Pro-OH; L-Threonylglycyl-L-serylglycyl-L-threonyl-L-proline; L-Proline, L-threonylglycyl-L-serylglycyl-L-threonyl-; H-TGSGTP-OH. Grades: ≥95%. CAS No. 922492-91-9. Molecular formula: C20H34N6O10. Mole weight: 518.52.
Fragment (28-32)-Calcitonin
Fragment (28-32)-Calcitonin is an impurity of Calcitonin salmon, which is a calcium regulating hormone used to be an effective alternative for the treatment of postmenopausal osteoporosis. Synonyms: H-Gly-Ser-Gly-Thr-Pro-OH; glycyl-L-serylglycyl-L-threonyl-L-proline; H-GSGTP-OH. Molecular formula: C16H27N5O8. Mole weight: 417.42.