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| Product | Description | |
|---|---|---|
| Fortimicin A | Produced by the strain of Micromonospora olivoasterospora, it has broad antibacterial spectrum and strong antibacterial activity, and is also effective to aminoglycoside antibiotic resistant bacteria producing 3'-phosphotransferase, 2''-nucleoside transferase, 6' and 2'-acetyltransferase. Alternative Names: Astromicin; Astromicina; Astromicine; Astromicinum; Antibiotic KW-1070; 4-Amino-1-((aminoacetyl)methylamino)-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-6-O-methyl-L-chiro-inositol. Grades: 95%. CAS No. 55779-06-1. Molecular formula: C17H35N5O6. Mole weight: 405.49. |  |
| Fortimicin B | Produced by the strain of Micromonospora olivoasterospora, it has a weak antibacterial activity. Alternative Names: Astromicin B; 4-Amino-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-beta-L-lyxo-heptopyranosyl)-6-O-methyl-1-(methylamino)-L-chiro-inositol. CAS No. 54783-95-8. Molecular formula: C15H32N4O5. Mole weight: 348.44. | |
| Fortunellin | Fortunellin is a potential anti-inflammation agent in inflammatory diseases, it targets miR-374a, which is a negative regulator of phosphatase and tensin homolog (PTEN). Fortunellin protects against high fructose-induced diabetic heart injury in mice by suppressing inflammation and oxidative stress via AMPK/Nrf-2 pathway regulation. Alternative Names: 7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one; Acacetin 7-O-neohesperidoside. CAS No. 20633-93-6. Molecular formula: C28H32O14. Mole weight: 592.55. | |
| Fosamprenavir | Fosamprenavir is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir (HY-17430). Fosamprenavir is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir can be used for the study of human immunodeficiency virus (HIV-1) infection[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Amprenavir phosphate; GW 433908. CAS No. 226700-79-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-78726. |  |
| Fosamprenavir calcium salt | Fosamprenavir calcium salt. Group: Biochemicals. Alternative Names: GW-433908G; Lexiva; Telzir. Grades: Highly Purified. CAS No. 226700-81-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C25H34CaN3O9PS. US Biological Life Sciences. |  Worldwide |
| Fosamprenavir Calcium Salt | Fosamprenavir Calcium Salt (GW433908G) is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir (HY-17430). Fosamprenavir Calcium Salt is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir Calcium Salt can be used for the study of human immunodeficiency virus (HIV-1) infection[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GW433908G. CAS No. 226700-81-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17431. | |
| Fosamprenavir Calcium Salt (GW-433908G, Lexiva, Telzir) | HIV protease inhibitor; water soluble prodrug of amprenavir. Group: Biochemicals. Alternative Names: GW-433908G; Lexiva; Telzir. Grades: Highly Purified. CAS No. 226700-81-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Fosamprenavir-d4 Calcium Salt (GW-433908G-d4, Lexiva-d4, Telzir-d4) | HIV protease inhibitor; water soluble prodrug of amprenavir. Group: Biochemicals. Alternative Names: GW-433908G-d4; Lexiva-d4; Telzir-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Fosaprepitant | Fosaprepitant. Uses: For analytical and research use. Alternative Names: (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid. CAS No. 172673-20-0. Molecular formula: C23H22F7N4O6P. Mole weight: 614.41. Catalog: APB172673200. |  |
| Fosaprepitant Benzyl Ester | Fosaprepitant Benzyl Ester. CAS No. 889852-02-2. | |
| Fosaprepitant-[d4] Dimeglumine | Fosaprepitant-[d4] Dimeglumine is a labelled form of Fosaprepitant Dimeglumine, which has been found to be a selective neurokinin-1 (NK-1) receptor antagonist. Alternative Names: [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl-d4)-4-morpholinyl]methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate 1-Deoxy-1-(methylamino)-D-glucitol; Fosaprepitant D4 Dimeglumine; MK-0517-d4; L785298-d4. Molecular formula: C37H52D4F7N6O16P. Mole weight: 1008.86. | |
| Fosaprepitant dimeglumine | Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, a water-soluble, N-phosphorylated prodrug of aprepitant with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant, this agent selectively binds to human substance P/neurokinin 1 (NK1) receptors in the central nervous system (CNS), inhibiting receptor binding of endogenous substance P and preventing substance P-induced emesis. Category: Active pharmaceutical ingredients. CAS No. 265121-04-8. Product ID: API265121048. Molecular formula: C37H56F7N6O16P. Mole weight: 1004.83. |  |
| Fosaprepitant dimeglumine | Fosaprepitant dimeglumine (MK-0517) is a proagent of Aprepitant (HY-10052). Fosaprepitant dimeglumine is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-0517; L785298. CAS No. 265121-04-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14407A. | |
| Fosaprepitant dimeglumine | Fosaprepitant is a selective NK-1 receptor antahonist. It is a water-soluble phosphoryl prodrug for Aprepitant. Alternative Names: MK-0517; MK 0517; MK0517. Grades: >98%. CAS No. 265121-04-8. Molecular formula: C23H22F7N4O6P.2C7H17NO5. Mole weight: 1004.83. | |
| Fosaprepitant Dimeglumine | Fosaprepitant is a selective neurokinin-1 (NK-1) receptor antahonist. Fosaprepitant is an antiemetic drug, a Aprepitant prodrug. Group: Biochemicals. Alternative Names: [3-[[ (2R, 3S) -2-[ (1R) -1-[3, 5-bis (trifluoromethyl) phenyl]ethoxy]-3- (4-fluorophenyl) -4-morpholinyl]methyl]-2, 5-dihydro-5-oxo-1H-1, 2, 4-triazol-1-yl]phosphonate 1-Deoxy-1-(methylamino)-D-glucitol; MK 0517. Grades: Highly Purified. CAS No. 265121-04-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Fosaprepitant Dimeglumine Impurity 1 | Fosaprepitant Dimeglumine Impurity 1. Uses: For analytical and research use. Molecular formula: C37H57F6N6O16P. Mole weight: 986.85. Catalog: APB08085. | |
| Fosaprepitant Ester Impurity 11 | Fosaprepitant Ester Impurity 11. Uses: For analytical and research use. Alternative Names: dimethyl (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate. Molecular formula: C25H26F7N4O6P. Mole weight: 642.46. Catalog: APB05964. | |
| Fosaprepitant Impurity 1 | A metabolite of Aprepitant. Alternative Names: [2R-[2α(S*),3α]]-5-[[2-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl]-1,2-dihydro-3H-1,2,4-Triazol-3-one. Grades: > 95%. CAS No. 170902-81-5. Molecular formula: C23H21F7N4O3. Mole weight: 534.44. | |
| Fosaprepitant Impurity 10 | Fosaprepitant Impurity 10. Uses: For analytical and research use. CAS No. 502537-15-7. Molecular formula: C21H19F6NO3. Mole weight: 447.38. Catalog: APB502537157. | |
| Fosaprepitant Impurity 11 | Fosaprepitant Impurity 11. Uses: For analytical and research use. CAS No. 1651828-04-4. Molecular formula: C27H24F7NO3. Mole weight: 543.48. Catalog: APB1651828044. | |
| Fosaprepitant Impurity 12 | Fosaprepitant Impurity 12. Uses: For analytical and research use. Molecular formula: C27H22F7NO2. Mole weight: 525.47. Catalog: APB08089. | |
| Fosaprepitant Impurity 13 | Fosaprepitant Impurity 13. Uses: For analytical and research use. Molecular formula: C27H22F7NO2. Mole weight: 525.47. Catalog: APB08090. | |
| Fosaprepitant Impurity 13 | Fosaprepitant Impurity 13. Uses: For analytical and research use. Alternative Names: (S)-4-benzyl-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)morpholin-3-one. CAS No. 327623-34-7. Molecular formula: C21H19F6NO3. Mole weight: 447.37. Catalog: APB327623347. | |
| Fosaprepitant Impurity 14 | Fosaprepitant Impurity 14. Uses: For analytical and research use. Molecular formula: C27H22F7NO2. Mole weight: 525.47. Catalog: APB08091. | |
| Fosaprepitant Impurity 15 | Fosaprepitant Impurity 15. Uses: For analytical and research use. Alternative Names: (2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-((5-oxo-1-phosphono-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)morpholine 4-oxide. Molecular formula: C23H22F7N4O7P. Mole weight: 630.41. Catalog: APB05959. | |
| Fosaprepitant Impurity 15 | Fosaprepitant Impurity 15. Uses: For analytical and research use. CAS No. 502537-39-5. Molecular formula: C20H20F7NO3. Mole weight: 455.37. Catalog: APB502537395. | |
| Fosaprepitant Impurity 16 | Fosaprepitant Impurity 16. Uses: For analytical and research use. CAS No. 2410426-96-7. Molecular formula: C14H13F6NO3. Mole weight: 357.25. Catalog: APB2410426967. | |
| Fosaprepitant Impurity 16 | Fosaprepitant Impurity 16. Uses: For analytical and research use. Alternative Names: 3-(hydroxymethyl)-1H-1,2,4-triazol-5(4H)-one. CAS No. 24021-90-7. Molecular formula: C3H5N3O2. Mole weight: 115.09. Catalog: APB24021907. | |
| Fosaprepitant Impurity 17 | Fosaprepitant Impurity 17. Uses: For analytical and research use. Alternative Names: 3-(methoxymethyl)-1H-1,2,4-triazol-5(4H)-one. Molecular formula: C4H7N3O2. Mole weight: 129.12. Catalog: APB05957. | |
| Fosaprepitant Impurity 17 | Fosaprepitant Impurity 17. Uses: For analytical and research use. CAS No. 172678-47-6. Molecular formula: C20H18F7NO2. Mole weight: 437.36. Catalog: APB172678476. | |
| Fosaprepitant Impurity 18 | Fosaprepitant Impurity 18. Uses: For analytical and research use. Alternative Names: benzyl dihydrogen phosphate. CAS No. 1623-07-0. Molecular formula: C7H9O4P. Mole weight: 188.12. Catalog: APB1623070. | |
| Fosaprepitant Impurity 18 | Fosaprepitant Impurity 18. Uses: For analytical and research use. Molecular formula: C20H18F7NO2. Mole weight: 437.36. Catalog: APB08092. | |
| Fosaprepitant Impurity 19 | Fosaprepitant Impurity 19. Uses: For analytical and research use. Alternative Names: (2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholine hydrochloride. Molecular formula: C20H20ClF6NO2. Mole weight: 455.82. Catalog: APB05958. | |
| Fosaprepitant Impurity 2 | Fosaprepitant Impurity 2. Uses: For analytical and research use. Alternative Names: ent-Fosaprepitant Dimeglumine; (3-(((2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl) ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid, meglumine (1:2). Molecular formula: C23H22F7N4O6P·2C7H17NO5. Mole weight: 1004.83. Catalog: APB05971. | |
| Fosaprepitant Impurity 20 | Fosaprepitant Impurity 20. Uses: For analytical and research use. Alternative Names: benzyl hydrogen (4-benzyl-3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate. Molecular formula: C37H34F7N4O6P. Mole weight: 794.65. Catalog: APB05956. | |
| Fosaprepitant Impurity 20 | Fosaprepitant Impurity 20. Uses: For analytical and research use. CAS No. 1707-92-2. Molecular formula: C21H21O4P. Mole weight: 368.37. Catalog: APB1707922. | |
| Fosaprepitant Impurity 21 | Fosaprepitant Impurity 21. Uses: For analytical and research use. Alternative Names: (4-benzyl-3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid. Molecular formula: C30H28F7N4O6P. Mole weight: 704.53. Catalog: APB05955. | |
| Fosaprepitant Impurity 22 | Fosaprepitant Impurity 22. Uses: For analytical and research use. Alternative Names: dibenzyl (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate. Molecular formula: C37H34F7N4O6P. Mole weight: 794.65. Catalog: APB05954. | |
| Fosaprepitant Impurity 23 | Fosaprepitant Impurity 23. Uses: For analytical and research use. Molecular formula: C23H23F7N4O9P2. Mole weight: 694.39. Catalog: APB08093. | |
| Fosaprepitant Impurity 24 | Fosaprepitant Impurity 24. Uses: For analytical and research use. CAS No. 172673-19-7. Molecular formula: C23H22F7N4O6P. Mole weight: 614.41. Catalog: APB172673197. | |
| Fosaprepitant Impurity 25 | Fosaprepitant Impurity 25. Uses: For analytical and research use. CAS No. 380499-07-0. Molecular formula: C20H16F7NO2. Mole weight: 435.34. Catalog: APB380499070. | |
| Fosaprepitant Impurity 26 | Fosaprepitant Impurity 26. Uses: For analytical and research use. Molecular formula: C10H8F6O. Mole weight: 258.16. Catalog: APB08086. | |
| Fosaprepitant Impurity 27 | Fosaprepitant Impurity 27. Uses: For analytical and research use. Molecular formula: C10H8F6O. Mole weight: 258.16. Catalog: APB08088. | |
| Fosaprepitant Impurity 28 | Fosaprepitant Impurity 28. Uses: For analytical and research use. Molecular formula: C10H8F6O. Mole weight: 258.16. Catalog: APB08094. | |
| Fosaprepitant Impurity 29 | Fosaprepitant Impurity 29. Uses: For analytical and research use. Molecular formula: C10H8F6O. Mole weight: 258.16. Catalog: APB08087. | |
| Fosaprepitant Impurity 3 | Fosaprepitant Impurity 3. Uses: For analytical and research use. Alternative Names: (1'R,2R,3R)-Fosaprepitant Dimeglumine; (3-(((2R,3R)-2-((R)-1-(3,5-bis(trifluoromethyl) phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid, meglumine (1:2). Molecular formula: C23H22F7N4O6P·2C7H17NO5. Mole weight: 1004.83. Catalog: APB05970. | |
| Fosaprepitant Impurity 3 | Fosaprepitant Impurity 3. Uses: For analytical and research use. CAS No. 265121-01-5. Molecular formula: C37H34F7N4O6P. Mole weight: 794.66. Catalog: APB265121015. | |
| Fosaprepitant Impurity 30 | Fosaprepitant Impurity 30. Uses: For analytical and research use. Molecular formula: C10H8F6O. Mole weight: 258.16. Catalog: APB08097. | |
| Fosaprepitant Impurity 31 | Fosaprepitant Impurity 31. Uses: For analytical and research use. Molecular formula: C20H18F7NO2. Mole weight: 437.36. Catalog: APB08095. | |
| Fosaprepitant Impurity 32 | Fosaprepitant Impurity 32. Uses: For analytical and research use. Molecular formula: C20H18F7NO2. Mole weight: 437.36. Catalog: APB08096. | |
| Fosaprepitant Impurity 33 | Fosaprepitant Impurity 33. Uses: For analytical and research use. Molecular formula: C20H18F7NO2. Mole weight: 437.36. Catalog: APB08100. | |
| Fosaprepitant Impurity 34 | Fosaprepitant Impurity 34. Uses: For analytical and research use. Molecular formula: C20H18F7NO2. Mole weight: 437.36. Catalog: APB08099. | |
| Fosaprepitant Impurity 35 | Fosaprepitant Impurity 35. Uses: For analytical and research use. Molecular formula: C20H18F7NO2. Mole weight: 437.36. Catalog: APB08098. | |
| Fosaprepitant Impurity 4 | Fosaprepitant Impurity 4. Uses: For analytical and research use. Alternative Names: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate. Molecular formula: C30H39F7N5O11P. Mole weight: 809.62. Catalog: APB05968. | |
| Fosaprepitant Impurity 4 | Fosaprepitant Impurity 4. Uses: For analytical and research use. CAS No. 889852-02-2. Molecular formula: C30H28F7N4O6P. Mole weight: 704.54. Catalog: APB889852022. | |
| Fosaprepitant Impurity 5 | Fosaprepitant Impurity 5. Uses: For analytical and research use. CAS No. 502537-07-7. Molecular formula: C13H12F3NO4. Mole weight: 303.24. Catalog: APB502537077. | |
| Fosaprepitant Impurity 5 | Fosaprepitant Impurity 5. Uses: For analytical and research use. Alternative Names: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate. Molecular formula: C30H39F7N5O11P. Mole weight: 809.62. Catalog: APB05969. | |
| Fosaprepitant Impurity 6 | Fosaprepitant Impurity 6. Uses: For analytical and research use. CAS No. 378223-36-0. Molecular formula: C11H13NO3. Mole weight: 207.23. Catalog: APB378223360. | |
| Fosaprepitant Impurity 6 | Fosaprepitant Impurity 6. Uses: For analytical and research use. Alternative Names: (1'R,2S,3R)-Fosaprepitant Dimeglumine; (3-(((2S,3R)-2-((R)-1-(3,5-bis(trifluoromethyl) phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid, meglumine (1:2). Molecular formula: C23H22F7N4O6P·2C7H17NO5. Mole weight: 1004.83. Catalog: APB05966. | |
| Fosaprepitant Impurity 7 | Fosaprepitant Impurity 7. Uses: For analytical and research use. Alternative Names: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2R,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate. Molecular formula: C30H39F7N5O11P. Mole weight: 809.62. Catalog: APB05967. | |
| Fosaprepitant Impurity 7 | Fosaprepitant Impurity 7. Uses: For analytical and research use. CAS No. 13657-16-4. Molecular formula: C10H13NO. Mole weight: 163.22. Catalog: APB13657164. | |
| Fosaprepitant Impurity 8 | Fosaprepitant Impurity 8. Uses: For analytical and research use. Alternative Names: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (3-(((2S,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate. Molecular formula: C30H39F7N5O11P. Mole weight: 809.62. Catalog: APB05965. | |
| Fosaprepitant Impurity 8 | Fosaprepitant Impurity 8. Uses: For analytical and research use. CAS No. 30071-93-3. Molecular formula: C10H6F6O. Mole weight: 256.15. Catalog: APB30071933. | |
| Fosaprepitant Impurity B | Fosaprepitant Impurity B. Uses: For analytical and research use. Alternative Names: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol hemi((3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-phenylmorpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate). Molecular formula: C23H23F6N4O6P·C14H34N2O10. Mole weight: 986.85. Catalog: APB05960. | |
| Fosaprepitant Impurity CYG | Fosaprepitant Impurity CYG. Uses: For analytical and research use. Alternative Names: dibenzyl (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)phosphonate. Molecular formula: C37H34F7N4O6P. Mole weight: 794.65. Catalog: APB05953. | |
| Fosaprepitant Impurity DBJ | Fosaprepitant Impurity DBJ. Uses: For analytical and research use. Alternative Names: benzyl hydrogen (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate. Molecular formula: C30H28F7N4O6P. Mole weight: 704.53. Catalog: APB05961. | |
| Fosaprepitant Impurity ELS | Fosaprepitant Impurity ELS. Uses: For analytical and research use. Alternative Names: (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-1H-1,2,4-triazole-1,4(5H)-diyl)diphosphonic acid. Molecular formula: C23H23F7N4O9P2. Mole weight: 694.39. Catalog: APB05962. | |
| Fosaprepitant Impurity NLS | Fosaprepitant Impurity NLS. Uses: For analytical and research use. Alternative Names: (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-1H-1,2,4-triazol-4(5H)-yl)phosphonic acid. Molecular formula: C23H22F7N4O6P. Mole weight: 614.41. Catalog: APB05963. | |
| Fosbretabulin disodium | Fosbretabulin disodium is the disodium salt of a water-soluble phosphate derivative of a natural stilbenoid phenol derived from the African bush willow (Combretum caffrum) with potential vascular disrupting and antineoplastic activities. Upon administration, the prodrug fosbretabulin is dephosphorylated to its active metabolite, the microtubule-depolymerizing agent combretastatin A4, which binds to tubulin dimers and prevents microtubule polymerization, resulting in mitotic arrest and apoptosis in endothelial cells. In addition, this agent disrupts the engagement of the endothelial cell-specific junctional molecule vascular endothelial-cadherin (VE-cadherin) and so the activity of the VE-cadherin/β-catenin/Akt signaling pathway, which may result in the inhibition of endothelial cell migration and capillary tube formation. As a result of fosbretabulin's dual mechanism of action, the tumor vasculature collapses, resulting in reduced tumor blood flow and ischemic necrosis of tumor tissue. Alternative Names: Combretastatin A-4 phosphate disodium, CA4P; CA4DP; Combretastatin A-4 phosphate. CAS No. 168555-66-6. Molecular formula: C18H19Na2O8P. Mole weight: 440.295. | |
| Fosbretabulin disodium | Fosbretabulin disodium (CA 4DP) is a tubulin destabilizing agent. Fosbretabulin disodium is the Combretastatin A4 proagent that selectively targets endothelial cells, induces regression of nascent tumour neovessels, reduces tumour blood flow and causes central tumour necrosis[1][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CA 4DP; CA 4P; Combretastatin A4 disodium phosphate. CAS No. 168555-66-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17449. | |
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