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| Product | Description | |
|---|---|---|
| Fostamatinib disodium hexahydrate | Fostamatinib disodium hexahydrate. Group: Biochemicals. Alternative Names: 6-[[5-Fluoro-2-[ (3, 4, 5-trimethoxyphenyl) amino]-4-pyrimidinyl]amino]-2, 2-dimethyl-4-[ (phosphonooxy) methyl]-2H-pyrido[3, 2-b]-1, 4-oxazin-3 (4H) -one sodium salt hydrate. Grades: Highly Purified. CAS No. 914295-16-2. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C23H36FN6Na2O15P. US Biological Life Sciences. |  Worldwide |
| Fostamatinib disodium hexahydrate | Fostamatinib (R788) disodium hexahydrate is the oral proagent of the active compound R406[1]. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM[2]. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM)[3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: R788 disodium hexahydrate. CAS No. 914295-16-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13038B. |  |
| Fostemsavir | Fostemsavir (BMS-663068) is the phosphonooxymethyl prodrug of BMS-626529. Fostemsavir (BMS-663068) is a novel attachment inhibitor that targets HIV-1 gp120 and prevents its binding to CD4+ T cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-663068. CAS No. 864953-29-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15440A. | |
| Fosthiazate | Fosthiazate is a broad-spectrum nematicide against various plant parasitic nematodes, including Meloidogyne spp., Globodera spp., and Pratylenchus spp., through inhibiting the synthesis of acetylcholinesterase[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 98886-44-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W020785. | |
| Fostriecin | The most fully characterised member of a family of phosphate esters of a triene antibiotic; a topoisomerase II inhibitor; selective inhibition of protein phosphatase PP2A. Alternative Names: (1E,7E,9E,11E)-3,6,13-trihydroxy-3-methyl-1-(6-oxo-3,6-dihydro-2H-pyran-2-yl)trideca-1,7,9,11-tetraen-4-yl dihydrogen phosphate; 2H-Pyran-2-one, 5,6-dihydro-6-[3,6,13-trihydroxy-3-methyl- 4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-, monosodiumsalt. Grades: >95% by HPLC. CAS No. 87810-56-8. Molecular formula: C19H27O9P. Mole weight: 430.39. |  |
| Fostriecin sodium salt | Fostriecin sodium salt is a protein phosphatase types 2A (PP2A) and 4 (PP4) inhibitor (IC50 = 1.5 nM and 3 nM, respectively). It also has an inhibitory effect on topoisomerase II (IC50 = 40 μM) and protein phosphatase type 1 (PP1) (IC50 = 131 μM). Fostriecin is found in Streptomyces pulveraceous. Uses: Enzyme inhibitors. Alternative Names: Fostriecin Sodium; Antibiotic CI 920 sodium salt; (6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-(phosphonooxy)-1,7,9,11-tridecatetraenyl]-2H-pyran-2-one sodium salt. Grades: ≥98% by HPLC. CAS No. 87860-39-7. Molecular formula: C19H26O9PNa. Mole weight: 452.37. | |
| Fotagliptin impurity 1 | Fotagliptin impurity 1. Uses: For analytical and research use. Alternative Names: (R)-2-((3-(3-aminopiperidin-1-yl)-6-(hydroxymethyl)-5-oxo-1,2,4-triazin-4(5H)-yl)methyl)-4-fluorobenzonitrile. Molecular formula: C17H19FN6O2. Mole weight: 358.37. Catalog: APB06057. |  |
| Fotemustine | Fotemustine is a chloroethylating nitrosourea with antineoplastic activity. Fotemustine alkylates guanine by forming chloroethyl adducts at the 6 position of guanine, resulting in N1-guanine and N3-cytosine cross linkages, inhibition of DNA synthesis, cell cycle arrest, and finally apoptosis. This agent is lipophilic and crosses the blood-brain barrier. Check for active clinical trials or closed clinical trials using this agent. Alternative Names: Muphoran, S 10036. Grades: >98%. CAS No. 92118-27-9. Molecular formula: C9H19ClN3O5P. Mole weight: 315.691. | |
| Foti 10:1 | Foti 10:1. |  CA, FL & NJ |
| Fo-Ti Extract (Ratio) | Fo-Ti Extract (Ratio). Group: Others. Purity: 4:1~20:1. Fo-Ti Extract (Ratio). Cat No: EXTW-034. |  |
| Fo-ti (polygonum multiflorum) oil | Fo-ti (polygonum multiflorum) oil. Product ID: CI-EO-0096. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Fo-Ti Root Powder (Polygonum Multiflorum) | Fo-Ti Root Powder (Polygonum Multiflorum). | CA, FL & NJ |
| Foundry Fluxes | Foundry Fluxes (blended, fused and granular). We offer a variety of products for diverse applications and maintain an extensive inventory at our warehouses to provide prompt shipment and on-time delivery to our customers. |  Worldwide |
| FOUNDRY RESIN | FOUNDRY RESIN. |  |
| Fourth International Standard for Streptomycin | Fourth International Standard for Streptomycin. Uses: For analytical and research use. Alternative Names: D-Streptamine. CAS No. 57-92-1. Molecular formula: C21H39N7O12. Mole weight: 581.57. IUPAC Name: 1-[(1R,2R,3S,4R,5R,6S)-3-carbamimidamido-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine. Catalog: APB57921. | |
| Fowlicidin-2 | Fowlicidin-2, which is composed of 31 amino acids, is widely expressed in the majority of tissues in chickens and has an important role in innate immunity. | |
| Fowlicidin 3 | Fowlicidin-3 is an alpha-helical cationic host defense peptide with potent antibacterial and lipopolysaccharide-neutralizing activities. It is highly potent against a broad range of Gram-negative and Gram-positive bacteria in vitro, including antibiotic-resistant strains, with minimum inhibitory concentrations in the range 1-2 microM. | |
| Fox04 | FOXO4 is a peptide antagonist intended to reverse ageing effects in animal subjects through selective induction of apoptosis of senescent cells. Grades: 95.2%. Molecular formula: C228H388N86O64. Mole weight: 5358.05. | |
| FOXM1-IN-1 | FOXM1-IN-1 is a potent FOXM1 inhibitor with an IC50 value of 2.65 μM. FOXM1-IN-1 shows antiproliferative activity. FOXM1-IN-1 decreases the the expression of FOXM1, PLK1, CDC25B protein[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2864407-22-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151986. | |
| FoxO1 Antibody [J3J15] | FKHR/FOXO1,FoxO1,FOXO1A. Group: Antibodies. Alternative Names: FKHR/FOXO1,FoxO1,FOXO1A. Pack Sizes: 20ul. Product ID: F0141. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| FOXO1-IN-3 | FOXO1-IN-3 is a highly-selective and orally active FOXO1 inhibitor. FOXO1-IN-3 reduces hepatic glucose production in mice. FOXO1-IN-3 improves insulin sensitivity and glucose control in db/db mice without causing weight gain[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2451093-95-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153617. | |
| FOXO4-DRI | FOXO4-DRI is a peptide acting as a specific FOXO4 blocker. It has been demonstrated to alleviate age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice.FOXO4-DRI is a peptide acting as a specific FOXO4 blocker. It has been demonstrated to alleviate age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice. FOXO4-DRI is a standard FOXO4 protein that is synthesized to prevent normal FOXO4 from binding to p53, thereby eliminating senescent cells and improving organ function and the ''biological age'' of young tissues. FOXO4-DRI affects a variety of cellular processes, including insulin signaling, cell cycle regulation, and oxidative stress signaling pathways, it is a cell-penetrative peptide, meaning it can enter cells from the inside and perform its role, and it has been shown in animal studies to selectively induce apoptosis in senescence cells, potentially reversing some of the effects of aging. Alternative Names: FOXO 4-DRI; Anti-aging peptide FOXO4-DRI; H-D-Leu-D-Thr-D-Leu-D-Arg-D-Lys-D-Glu-D-Pro-D-Ala-D-Ser-D-Glu-D-Ile-D-Ala-D-Gln-D-Ser-D-Ile-D-Leu-D-Glu-D-Ala-D-Tyr-D-Ser-D-Gln-D-Asn-D-Gly-D-Trp-D-Ala-D-Asn-D-Arg-D-Arg-D-Ser-D-Gly-D-Gly-D-Lys-D-Arg-D-Pro-D-Pro-D-Pro-D-Arg-D-Arg-D-Arg-D-Gln-D-Arg-D-Arg-D-Lys-D-Lys-D-Arg-D-Gly-OH; Forkhead box O transcription factor 4-D-Retro-Inverso; Proxofim; D-Retro Inv. Grades: 95%. CAS No. 2460055-10-9. Mol | |
| FOXO4-DRI | FOXO4-DRI is a cell-permeable peptide antagonist that blocks the interaction of FOXO4 and p53. FOXO4-DRI is a senolytic peptide that induces apoptosis of senescent cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2460055-10-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4157. | |
| Foxy 5 | Foxy 5. Group: Biochemicals. Grades: Purified. CAS No. 881188-51-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Foxy-5 | Foxy-5, a WNT5A agonist, is a mimicking peptide of WNT5A which is a non-canonical member of the Wnt family. Foxy-5 triggers cytosolic free calcium signaling without affecting β-catenin activation and it impairs the migration and invasion of epithelial cancer cells. Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 881188-51-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1416. | |
| Foxy-5 | A Wnt5a peptide mimetic. It has been undergoing clinical trials for the treatment of prostate cancer, colorectal cancer, metastatic colon cancer, metastatic breast cancer, and metastatic prostate cancer. Alternative Names: Foxy 5; Foxy5; (2S)-2-[[(2S)-4-carboxy-2-[[(2R)-2-[[2-[[(2S)-3-carboxy-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]propanoyl]amino]acetyl]amino]-3-sulfanylpropanoyl]amino]butanoyl]amino]-4-methylpentanoic acid. Grades: >95%. CAS No. 881188-51-8. Molecular formula: C26H42N6O12S2. Mole weight: 694.8. | |
| FOY 251 | FOY 251 is a metabolite of camostat mesilate, and a proteinase inhibitor. Alternative Names: Foy 251;71079-09-9;4-(4-Guanidinobenzoyloxy)phenylacetic acid;FOY-251 mesylate;FOY251;4-GBCE (methanesulfonate);2-(4-((4-Guanidinobenzoyl)oxy)phenyl)acetic acid methanesulfonic acid salt;2-[4-[4-(diaminomethylideneamino)benzoyl]oxyphenyl]acetic acid;methanesulfonic acid;CHEMBL433135;FOY-251 mesylate?;4-[[4-[(AMINOIMINOMETHYL)AMINO]BENZOYL]OXY]-BENZENEACETIC ACID MONOMETHANESULFONATE;SCHEMBL1649708;SCHEMBL11417275;DTXSID20991365;EX-A5589;HY-19727A;MFCD09842546;s3511;AKOS030614588;CS-0016501;EN300-7455534;4-(4-Guanidinobenzoyloxy)-phenylacetic acid x Methanesulfonic acid;2-[4-(4-carbamimidamidobenzoyloxy)phenyl]acetic acid; methanesulfonic acid;[4-(4-CARBAMIMIDAMIDOBENZOYLOXY)PHENYL]ACETIC ACID; METHANESULFONIC ACID;{4-[(4-Carbamimidamidobenzoyl)oxy]phenyl}acetic acid--methanesulfonic acid (1/1);2-(4-((4-Guanidinobenzoyl)oxy)phenyl)acetic acid compound with methanesulfonic acid (1:1);2-(4-((4-guanidinobenzoyl)oxy)phenyl)acetic acid--methanesulfonic acid (1/1);Benzeneacetic acid, 4-((4-((aminoiminomethyl)amino)benzoyl)oxy)-, monomethanesulfonate. CAS No. 71079-09-9. Molecular formula: C9H10BrFN2O5. Mole weight: 325.09. | |
| FOY 251 | A metabolite of Camostat. It is a pollen protease inhibitor for prevention and control of allergy. Group: Biochemicals. Alternative Names: 4-[[4-[ (Aminoiminomethyl) amino]benzoyl]oxy]-benzeneacetic Acid Monomethanesulfonate. Grades: Highly Purified. CAS No. 71079-09-9. Pack Sizes: 1mg. Molecular Formula: C??H??N?O?S, Molecular Weight: 409.41. US Biological Life Sciences. | Worldwide |
| FOY 251 | FOY 251, an anti-proteolytic active metabolite Camostate (HY-13512), acts as a proteinase inhibitor[1][2]. FOY 251 inhibits SARS-CoV-2 infection in cells assay[1][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 71079-09-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19727A. | |
| FOY 251 Benzyl Ester Hydrochloride | Protected Camostat metabolite. Group: Biochemicals. Alternative Names: 4- [ [4- [ (Aminoiminomethyl) amino] benzoyl] oxy] benzeneacetic Acid Benzyl Ester Hydrochloride; 4- [ [4- [ (Aminoiminomethyl) amino] benzoyl] oxy] benzeneacetic Acid Phenylmethyl Ester Hydrochloride. Grades: Highly Purified. CAS No. 71079-12-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| FPA-124 | FPA-124, a cell-permeable copper complex, is a selective Akt inhibitor with an IC50 of 0.1 μM. FPA-124 interacts with both the pleckstrin homology (PH) and the kinase domains of Akt. FPA-124 induces apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 902779-59-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15369. | |
| FP-biotin | FP-biotin. Group: Biochemicals. Alternative Names: [10- [ [5- [ [5- [ (3aS, 4S, 6aR) -Hexahydro-2-oxo-1H-thieno [3, 4-d] imidazol-4-yl] -1-oxopentyl] amino] pentyl] amino] -10-oxodecyl] phosphonofluoridic acid ethyl ester; 10-Fluoroethoxyphosphinyl -N-biotinamidopentyl decanamide. Grades: Highly Purified. CAS No. 259270-28-5. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C27H50FN4O5PS. US Biological Life Sciences. | Worldwide |
| FP-Biotin | FP-biotin is a potent organophosphorus toxicant, well-suited for searching for new biomarkers of organophosphorus toxicants exposure. FP-Biotin quantifies FAAH, ABHD6, and MAG-lipase activity. FP-biotin is used for studies with plasma because biotinylated peptides are readily purified by binding to immobilized avidin beads[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 259270-28-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-136924. | |
| FP-Biotin. | FP-Biotin. Group: Biochemicals. Alternative Names: [10- [ [5- [ [5- [ (3aS, 4S, 6aR) -Hexahydro-2-oxo-1H-thieno [3, 4-d] imidazol-4-yl] -1-oxopentyl] amino] pentyl] amino] -10-oxodecyl] phosphonofluoridic Acid Ethyl Ester; 10-Fluoroethoxyphosphinyl -N-biotinamidopentyl decanamide. Grades: Highly Purified. CAS No. 259270-28-5. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| FPFS-1169 HCl | FPFS-1169 HCl. CAS No. 265130-22-1. | |
| FPFT-2216 | FPFT-2216, a molecular glue compound, degrades phosphodiesterase 6D (PDE6D), zinc finger transcription factors Ikaros (IKZF1), Aiolos (IKZF3), and casein kinase 1α (CK1α). FPFT-2216 can be used for the research of cancer and inflammatory disease[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2367619-87-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145319. | |
| Fpg Protein from Escherichia coli | Fpg Protein from Escherichia coli. Uses: For analytical and research use. CAS No. 78783-53-6. Catalog: AP78783536. | |
| Fpg Protein from Escherichia coli, Recombinant | Fpg protein, a key enzyme in the DNA base excision repair pathway (BER), catalyses the excision of a broad spectrum of modified purines such as formamidopyrimidine (Fapy) and 8-oxoguanine (8-oxo-G). Fpg possess both DNA glycosylase activity that removes the mutated base and AP-lyase activity that releases ribose, leaving both 5'-and 3'-phosphorylated ends in the DNA. Several analytical methods based on Fpg protein activity in vitro were developed for detection and quantitation of oxidative damage to DNA mainly for FapyA, FapyG and 8-oxo-G. The fpg gene was cloned by Boiteux, et al. Fpg protein possess a zinc finger motif at its C-terminus (one zinc atom per molecule). Protein. Mole weight: mol wt 30.2 kDa (269 amino acids, predicted from the nucleotide sequence). Activity: >20 ,000 units/mg protein. Storage: -20°C. Form: buffered aqueous glycerol solution; Solution in 50% glycerol containing 50 mM potassium HEPES, pH 7.5, 1 mM DTT, 1 mM EDTA, and 200 mM NaCl. Source: E. coli. Species: Escherichia coli. Fapy-DNA glycosylase; deoxyribonucleate glycosidase; 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase; 2,6-diamino-4-hydroxy-5 (N-methyl)formamidopyrimidine-DNA glycosylase; formamidopyrimidine-DNA glycosylase; DNA-formamidopyrimidine glycosidase; Fpg protein; DNA-formamidopyrimidine glycosylase; EC 3.2.2.23; 78783-53-6. | |
| FPH1 | FPH1(BRD-6125) increases the number and activity of primary human hepatocytes in vitro and promotes the differentiation of iPS cells towards a hepatic lineage[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BRD6125. CAS No. 708219-39-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-100590. | |
| FPL 55712 | FPL 55712. Group: Biochemicals. Grades: Purified. CAS No. 40785-97-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| FPL64176 | FPL64176, a nondihydropyridine compound, is a potent agonist of L-type Ca2+ channels with an EC50 value of 16 nM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 120934-96-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103307. | |
| FPL 64176 | FPL 64176. Group: Biochemicals. Grades: Purified. CAS No. 120934-96-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FPR1 antagonist 1 | FPR1 antagonist 1 (compound 24a) is a formyl peptide receptor 1 (FPR1) antagonist with an IC50 of 25 nM. FPR1 antagonist 1 inhibits cell growth through a combined effect on cell proliferation and apoptosis and reduces cell migration, while inducing an increase in angiogenesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3053980-28-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156293. | |
| FPR1 antagonist 3 | FPR1 antagonist 3 (compound 10) is a potent and selective FPR1 antagonist. FPR1 antagonist 3 inhibits superoxide anion generation and elastase release with IC50s of 0.33 and 0.84 μM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3058943-53-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-176403. | |
| FPR2 agonist 3 | FPR2 agonist 3 (compound CMC23) can limit the lactate dehydrogenase release in LPS (HY-D1056) -stimulated cultures and decrease the levels of pro-inflammatory IL-1β and IL-6. FPR2 agonist 3 decrease the level of phosphor-STAT3 via the STAT3/SOCS3 signaling pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2829263-19-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155335. | |
| FPR A14 | FPR A14. Group: Biochemicals. Grades: Purified. CAS No. 329691-12-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FPR Agonist 43 | FPR Agonist 43 (compound 43) is a dual formyl peptide receptor 1 (FPR1) and formyl peptide receptor 2 (FPR2)/ALX agonist[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 903895-98-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19574. | |
| FPS-ZM1 | FPS-ZM1 is a high-affinity and BBB-permeable RAGE inhibitor with a Ki of 25 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 945714-67-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-19370. | |
| FPS-ZM1 | FPS-ZM1 is a high-affinity RAGE-specific blocker that inhibits amyloid-β binding to the V domain of RAGE with Ki of 25 ± 5 nM in RAGE-transfected CHO cells. It binds exclusively to RAGE and inhibits β-secretase activity and Aβ production. It also suppresses microglia activation and the neuroinflammatory response in brain. It penetrates the blood-brain barrier and binds to RAGE, thus reducing the protein levels of various cytokines. It inhibits RAGE-mediated influx of circulating Aβ40 and Aβ42 into the brain. It is not toxic to mice and can easily cross the blood-brain barrier in vivo. It might be a novel therapeutic agent to treat AD patients. Uses: Fps-zm1 might be a novel therapeutic agent to treat ad patients. Alternative Names: FPS-ZM1; FPS ZM1; FPSZM1; FPS-ZM 1; FPS ZM-1; FPSZM 1; N-benzyl-4-chloro-N-cyclohexylbenzaMide;4-Chloro-N-cyclohexyl-N-(phenylmethyl)benzamide. Grades: >98 %. CAS No. 945714-67-0. Molecular formula: C20H22ClNO. Mole weight: 327.85. | |
| FP-TZTP | FP-TZTP. Group: Biochemicals. Alternative Names: 3-[4-[(3-Fluoropropyl)thio]-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridine. Grades: Highly Purified. CAS No. 424829-90-3. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C11H16FN3S2. US Biological Life Sciences. | Worldwide |
| FR054 | FR054 is an inhibitor of the HBP enzyme PGM3, with a remarkable anti-breast cancer effect[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 35954-65-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-124909A. | |
| Fr 122047 hydrochloride | Fr 122047 hydrochloride. CAS No. 130717-51-0. Purity: >98 %. Product ID: ACM130717510. Molecular formula: C23H25N3O3S.HCl. Mole weight: 459.99. Alfa Chemistry - ISO 9001:32057 Certified. | |
| FR 122047 hydrochloride | FR 122047 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 130717-51-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FR 139317 | FR 139317. Group: Biochemicals. Grades: Purified. CAS No. 142375-60-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FR 171113 | FR 171113. Group: Biochemicals. Grades: Purified. CAS No. 173904-50-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FR 179642 | FR 179642 is an impurity of Micafungin, which is an antifungal agent. Alternative Names: FR-179642; FR179642; Pneumocandin M1; 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]-4-[(S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]pneumocandin A0; CMICA; FR 133303. Grades: ≥95%. CAS No. 168110-44-9. Molecular formula: C35H52N8O20S. Mole weight: 936.89. | |
| FR-179642 | FR-179642. Group: Biochemicals. Grades: Highly Purified. CAS No. 168110-44-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C35H52N8O20S. US Biological Life Sciences. | Worldwide |
| FR 180204 | FR 180204 is an ATP-competitive and selective ERK inhibitor. FR 180204 inhibits ERK1 and ERK2 with IC50s of 0.51 μM (Ki=0.31 μM) and 0.33 μM (Ki=0.14 μM), respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 865362-74-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12275. | |
| FR 180204 | FR 180204. Group: Biochemicals. Grades: Purified. CAS No. 865362-74-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| FR-182877 | FR-182877 is produced by the strain of Streptomyces sp. No. 9885. It has a strong effect on rat ascites and solid tumors in vivo, and has no antibacterial activity. Molecular formula: C24H32O5. Mole weight: 400.51. | |
| FR-191512 | It is a polyphenolic compound with anti-influenza A virus effect. Alternative Names: FR191512. Molecular formula: C38H38O16. Mole weight: 750.70. | |
| FR194738 | FR194738 is a squalene epoxidase inhibitor. FR194738 inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 204067-52-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100303A. | |
| FR194921 | FR194921 is a potent, selective and orally active and cross the blood-brain barrier Adenosine A1 antagonist with Ki value of 6.6, 5400 nM for A1, A2A, respectively. FR194921 shows cognitive-enhancing and anxiolytic activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 202646-80-8. Pack Sizes: 5 mg. Product ID: HY-116800. | |
| FR198248 | FR-198248, a new type of hydroxyl benzaldehyde compound, was isolated from the cultured broth of a fungal strain identified as Aspergillus terreus from morphological characteristics. FR-198248 exhibited anti-influenza virus activity in Madin-Darby canine kidney (MDCK) cells in vitro. Alternative Names: FR-198248;1,5,6,7-Isobenzofurantetrol, 1,3-dihydro-4-methyl-;197316-54-4;1-O-Demethyl-FR-202306;6ZL0C9ER7N;2,3,4-trihydroxy-6-(hydroxymethyl)-5-methylbenzaldehyde;364342-83-6;UNII-6ZL0C9ER7N;SCHEMBL1527081;Q27265782. Grades: >98%. CAS No. 197316-54-4. Molecular formula: C9H10O5. Mole weight: 198.17. | |
| FR225659 | FR225659 is originally isolated from Helicomyces sp. No. 19353. It can suppress the gluconeogenesis induced by Glucagon in Primary hepatocytes of rats. Molecular formula: C36H42ClN7O8. Mole weight: 736.21. | |
| FR-235222 | FR-235222 is an immunosuppressive substance that inhibits mammalian histone deacetylase (HDAC). It is produced by the strain of Acremonium sp. No. 27082. Alternative Names: FR 235222; FR235222. Molecular formula: C30H44N4O6. Mole weight: 556.69. | |
| FR 236924 | FR 236924. Group: Biochemicals. Grades: Purified. CAS No. 28399-31-7. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| FR-245 | FR-245. CAS No. 25713-60-4. Molecular formula: C21H6Br9N3O3. Mole weight: 1067.4g/mol. IUPAC Name: 2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine. SMILES: C1=C(C=C(C(=C1Br)OC2=NC(=NC(=N2)OC3=C(C=C(C=C3Br)Br)Br)OC4=C(C=C(C=C4Br)Br)Br)Br)Br. InChI: InChI=1S/C21H6Br9N3O3/c22-7-1-10(25)16(11(26)2-7)34-19-31-20(35-17-12(27)3-8(23)4-13(17)28)33-21(32-19)36-18-14(29)5-9(24)6-15(18)30/h1-6H. | |
| FR 252921 | FR 252921 is produced by the strain of Pseudomonas fluorenscens No. 408813. It shows immunosuppressive effect in mice in vivo and in vitro, and has synergistic effect with FK-506. Molecular formula: C29H44N2O5. Mole weight: 500.67. | |
| FR-252922 | FR-252922 is produced by the strain of Pseudomonas fluorenscens No. 408813. It shows immunosuppressive effect in mice in vivo and in vitro, and has synergistic effect with FK-506. Molecular formula: C31H48N2O5. Mole weight: 528.72. | |
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