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A 1, 2, 4-triazole derived compound that acts as a potent ghrelin receptor (GHS-R1a) antagonist (IC50 = 32nM in a binding assay, dissociation constant Kb = 19nM). Shown to reduce hexarelin-induced food intake [hexarelin (80ug/kg, cumulative food intake (g of food/100g of body weight) at 6h by acute administration (sc) of JMV 2959 (160ug/kg)] in rats without affecting the basal food intake. Also suppresses ghrelin and fasting-induced food intake at the level of the central nervous system. Reported to suppress genes up-regulated by ghrelin. Does not affect intracellular Ca2+ mobilization. Group: Biochemicals. Alternative Names: (R)-N-(2-(1H-indol-3-yl)-1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)ethyl)-2-aminoacetamide Hydrochloride, GHSR1a Antagonist, GH Secretagogue Receptor Antagonist, JMV2959, Growth Hormone Secretagogue Receptor Antagonist. Grades: Highly Purified. CAS No. 925238-89-7. Pack Sizes: 10mg. Molecular Formula: C??H??N?O, Molecular Weight: 254.29. US Biological Life Sciences.
Worldwide
Ghrelin receptor full agonist-2
Ghrelin receptor full agonist-2 is a highly potent Ghrelin receptor full agonist. Synonyms: 5-(2-chlorophenyl)-N-((3R,4S)-1-(phenylsulfonyl)-4-(((S)-piperidin-3-yl)carbamoyl)pyrrolidin-3-yl)isoxazole-3-carboxamide. CAS No. 2602452-73-1. Molecular formula: C26H28ClN5O5S. Mole weight: 558.05.
GHRP-6
Growth hormone-releasing peptides (GHRPs) are synthetic, non-natural peptides endowed with potent stimulatory effects on somatotrope secretion in animals and humans. Growth hormone releasing peptide-6 can promote the secretion of growth hormone, regulate food intake, increase weight, and promote animal growth. Synonyms: Hexapeptide-2; GH-Releasing peptide; His(1)-lys(6)-ghrp; His-(D-Trp)-Ala-Trp-(D-Phe)-Lys-NH2. CAS No. 87616-84-0. Molecular formula: C46H56N12O6. Mole weight: 872.98.
GI 181771
GI-181771X is a novel effect of oral CCK-1 agonist on fasting and postprandial gastric functions in healthy volunteers. Uses: A novel effect of oral cck-1 agonist. Synonyms: GI-181771X; GI181771X; GI 181771X; GSKI 181771X; GSKI-181771X; GSKI181771X; (S)-3-(3-(1-(2-(isopropyl(phenyl)amino)-2-oxoethyl)-2,4-dioxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)ureido)benzoic acid. Grade: ≥96%. CAS No. 305366-98-7. Molecular formula: C34H31N5O6. Mole weight: 605.22.
GI254023X
GI254023X is a potent MMP9 and ADAM10 inhibitor with IC50s of 2.5 and 5.3 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GI4023; SRI028594. CAS No. 260264-93-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19956.
GI 254023X
GI 254023X is a selective ADAM10 metalloprotease inhibitor with over 100-fold higher potency at ADAM10 than ADAM17. GI 254023X inhibits the proliferation of H929 cells, and calcium ionophore-induced betacellulin shedding in IMPE cells. It prevents E-cadherin cleavage in A549 cells, and suppresses ADAM10 mediated neuronal outgrowth of dorsal root ganglion neurons in vitro. Synonyms: GI254023X; GI 254023X; GI-254023X; GI4023; GI-4023; GI 4023. (2R)-N-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl]propyl]-2-[(1S)-1-(N-hydroxyformamido)ethyl]-5-phenylpentanamide. Grade: ≥98% by HPLC. CAS No. 260264-93-5. Molecular formula: C21H33N3O4. Mole weight: 391.5.
GI254023X (GI4023)
GI254023X (GI 4023, SRI028594) is a selective inhibitor of ADAM10 with 100-fold selectivity for ADAM10 over ADAM17. The IC50 values for recombinant ADAM10 amd ADAM17 are 5.3 nM and 541 nM, respectively.GI254023X can inhibit MMP9. Group: Inhibitors. Alternative Names: GI 4023, SRI028594. CAS No. 260264-93-5. Pack Sizes: 2mg. Product ID: S8660. Formula: C21H33N3O4. Smiles: CC(C(CCCC1=CC=CC=C1)C(=O)NC(C(=O)NC)C(C)(C)C)N(C=O)O. Storage Conditions: 3 years -20°C powder.
United States; Europe
GI 530159
GI 530159 is a TREK1 and TREK2 channel activator exhibiting selectivity for TREK1/2 over TRAAK, TASK3 and a range of other potassium channels. Synonyms: 4,4'-[[2,2,2-Trifluoro-1-(trifluoromethyl)ethylidene]bis(4,1-phenyleneoxy)]bis[benzenamine]; 4,4'-(Hexafluoroisopropylidene)bis(p-phenyleneoxy)dianiline. Grade: ≥ 99 % by HPLC. CAS No. 69563-88-8. Molecular formula: C27H20F6N2O2. Mole weight: 518.45.
Giant Knotweed Extract (Standard)
Giant Knotweed Rhizome is the dry rhizome and root of Polygonum cuspidatum Sieb. et Zucc. Harvest at spring and autumn every year, and remove the fibrous root, make it clean, and then cut it into short pieces or junks, open-air drying. Applications: Studies suggest that resveratrol has anti-atherosclerotic activity and that it might have some immune-stimulating and anti-cancer effects. human studies are few in number and inconclusive due to short duration and poor design. Group: Others. CAS No. 501-36-0. Purity: 50.0%, 98.0% Resveratrol HPLC. Mole weight: 228.24. Giant Knotweed Extract (Standard); 501-36-0; C14H12O3. Cat No: EXTW-011.
Gibberellenic Acid
Gibberellenic Acid is a derivative of Gibberellic Acid. It is used for plant-growth stimulation. Synonyms: (1α,2β,10β)-2,7-Dihydroxy-1-methyl-8-methylene-gibba-3,4a-diene-1,10-dicarboxylic Acid; 2β,7-Dihydroxy-1-methyl-8-methylene-gibba-3,4a-diene-1α,10β-dicarboxylic Acid. Grade: > 95%. CAS No. 546-09-8. Molecular formula: C19H22O6. Mole weight: 346.38.
Gibberellic acid
Gibberellic acid is a hormone found in plants and fungi. It is a simple gibberellin, a pentacyclic diterpene acid promoting growth and elongation of cells. Uses: Plant growth regulators. Synonyms: Gibberellin A3; Gibberellic acid GA3; Gibreskol; Berelex; Brellin; Cekugib; Pro-Gibb; (1alpha,2beta,4aalpha,4bbeta,10beta)-2,4a,7-Trihydroxy-1-methyl-8-methylenegibb-3-ene-1,10-dicarboxylic acid 1,4a-lactone. Grade: 90%. CAS No. 77-06-5. Molecular formula: C19H22O6. Mole weight: 346.38.
Gibberellic acid
Gibberellic acid (GA3) is a natural plant growth regulator with oral bioactivity. Gibberellic acid governs multiple plant developmental events, including seed germination, cell elongation, floral organ formation, and rice spikelet fertility. Gibberellic acid optimizes root morphology and secondary metabolite production in Echinacea purpurea hairy roots, and serves as a bioactive seed priming agent to improve chilling stress tolerance in chickpea. Gibberellic acid mediates modulation of enzyme activity and secondary metabolism in plants and exerts tissue-specific regulatory effects on antioxidant systems and lipid peroxidation in rats. Gibberellic acid can be used in studies of plant growth, metabolism, and abiotic stress responses[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gibberellin A3. CAS No. 77-06-5. Pack Sizes: 10 mM * 1 mL in DMSO; 500 mg; 1 g; 5 g. Product ID: HY-N1964.
Gibberellic acid
25g Pack Size. Group: Analytical Reagents, Biochemicals, Diagnostic Raw Materials. Formula: C19H22O6. CAS No. 77-06-5. Prepack ID 84003407-25g. Molecular Weight 346.37. See USA prepack pricing.
Gibberellic Acid
Gibberellic acid promotes internode elongation & breaks certain dormancies in seeds. Alternative Names: Ryzupstrong. CAS No. 77-06-5. Purity: 95%. Product ID: ACM77065-3. Molecular formula: C19H22O6. Mole weight: 346.38. IUPAC Name: (1R,2R,5S,8S,9S,10R,11S,12S)-5,12-Dihydroxy-11-methyl-6-methylidene-16-oxo-15-oxapentacyclo[9.3.2.15,8.01,10.02,8]heptadec-13-ene-9-carboxylic acid. Canonical SMILES: CC12C(C=CC3(C1C(C45C3CCC(C4)(C(=C)C5)O)C(=O)O)OC2=O)O. Alfa Chemistry - ISO 9001:32057 Certified.
Gibberellic Acid
Gibberellic Acid. Market: Agriculture. PK Chem Industries: We supply chemicals related to Cosmetic, Personal Care, Food, Pharmaceutical, Feed, Agriculture and Mining Industries.
Gibberellic Acid
Gibberellic Acid is a a pentacyclic diterpene acid. Gibberellic Acid is a hormone that is found in plants which promotes the growth and elongation of cells. Gibberellic acid acts as a plant growth regulator on account of its physiological and morphological effects in extremely low concentrations. Generally Gibberellic acid affects only the plant parts above the soil surface. Group: Biochemicals. Alternative Names: (1α,2 β,4aα,4b β,10 β)-2,4a,7-Trihydroxy-1-methyl-8-methylenegibb-3-ene-1,10-dicarboxylic Acid 1,4a-Lactone, ; Gibberellin A3; (+)-Gibberellic Acid; (+)-Gibberellin A3; Activol; Arbostim; Berelex; GA; GA3; GibGro; Gibberellic Acid GA3; Gibberellin GA3; Gibrescol; Gibreskol; Grocel GA3; Maxon; NSC 14190; NSC 19450; Pro-Gibb; Pro-Gibb Plus; Ralex; Release LC; RyzUp; TU 64-3-103-75. Grades: Highly Purified. CAS No. 77-06-5. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. US Biological Life Sciences.
Worldwide
Gibberellic Acid 3-Isolactone
Gibberellic Acid 3-Isolactone is a structural analog of Gibberellic Acid. It shows plant growth-promoting activity. Synonyms: (4bβ)-1-Methyl-2β,3α,7-trihydroxy-8-methylenegibba-4-ene-1α,10β-dicarboxylic acid 1,3-lactone; 2β,3α,7-Trihydroxy-1-methyl-8-methylenegibb-4-ene-1α,10β-dicarboxylic acid 1,3-lactone; Isogibberellic acid; Isogibberellin A3; (1α,2β,3α,4bβ,10β)-2,3,7-Trihydroxy-. Grade: > 95%. CAS No. 19123-67-2. Molecular formula: C19H22O6. Mole weight: 346.38.
Gibberellic Acid Acetate is an intermediate in the synthesis of Gibberellin A7 which is a plant hormone that was isolated from culture filtrates of the fungus Gibberella fujikuroi. Gibberellin A7 was shown to promote the growth and elongation of cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 7648-2-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C21H24O7. US Biological Life Sciences.
Worldwide
Gibberellic Acid Acetoxymethyl Ester
Gibberellic Acid Acetoxymethyl Ester is an analog of Gibberellic acid. Gibberellic acid acts as a plant growth regulator on account of its physiological and morphological effects in extremely low concentrations. Generally Gibberellic acid affects only the plant parts above the soil surface. Gibberellic acid is a hormone. Group: Biochemicals. Alternative Names: (1α,2 β,4aα,4b β,10 β)-2,4a,7-Trihydroxy-1-methyl-8-methylenegibb-3-ene-1,10-dicarboxylic Acid 1,4a-Lactone Acetoxymethyl Ester; GA3-AM. Grades: Highly Purified. CAS No. 1373154-68-7. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
Gibberellic acid methyl ester
Gibberellic acid methyl ester. Group: Biochemicals. Grades: Highly Purified. CAS No. 510-50-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C20H24O6. US Biological Life Sciences.
Also acts on a number of other gibberellins. Group: Enzymes. Synonyms: gibberellin 2β-hydroxylase. Enzyme Commission Number: EC 1.14.11.13. CAS No. 85713-20-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0629; gibberellin 2β-dioxygenase; EC 1.14.11.13; 85713-20-8; gibberellin 2β-hydroxylase. Cat No: EXWM-0629.
gibberellin 3β-dioxygenase
Requires Fe2+ and ascorbate. Group: Enzymes. Synonyms: gibberellin 3β-hydroxylase; (gibberrellin-20),2-oxoglutarate: oxygen oxidoreductase (3β-hydroxylating). Enzyme Commission Number: EC 1.14.11.15. CAS No. 120860-89-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0631; gibberellin 3β-dioxygenase; EC 1.14.11.15; 120860-89-1; gibberellin 3β-hydroxylase; (gibberrellin-20),2-oxoglutarate: oxygen oxidoreductase (3β-hydroxylating). Cat No: EXWM-0631.
gibberellin-44 dioxygenase
Requires Fe2+. Group: Enzymes. Synonyms: oxygenase, gibberellin A44 oxidase; (gibberellin-44), 2-oxoglutarate:oxygen oxidoreductase. Enzyme Commission Number: EC 1.14.11.12. CAS No. 112198-85-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0628; gibberellin-44 dioxygenase; EC 1.14.11.12; 112198-85-3; oxygenase, gibberellin A44 oxidase; (gibberellin-44), 2-oxoglutarate:oxygen oxidoreductase. Cat No: EXWM-0628.
Gibberellin A1 is a derivative of Gibberellic Acid. Synonyms: 2β,4aα,7-Trihydroxy-1β-methyl-8-methylenegibbane-1α,10β-dicarboxylic acid 1,4a-lactone; 2β,4a,7-Trihydroxy-1-methyl-8-methylene-4aα,4bβ-gibbane-1α,10β-dicarboxylic Acid 1,4a-Lactone; 4a,1-(Epoxymethano)-7,9a-methanobenz[a]azulenegibbane-1,10-dicarboxylic Ac. Grade: > 95%. CAS No. 545-97-1. Molecular formula: C19H24O6. Mole weight: 348.40.
Gibberellin A1
Gibberellin A1 is a kind of plant hormones. Gibberellin A1 is a growth-promoting acids isolated from immature seed of Phaseolus multiflorus[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 545-97-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N7443.
Gibberellin A4 is a derivative of Gibberellic Acid. It is a plant growth hormone that regulates growth and differentiation of plant cells for elongation, germination and enzyme induction. Synonyms: 4a,1-(Epoxymethano)-7,9a-methanobenz[a]azulene, gibbane-1,10-dicarboxylic Acid Deriv.; GA4; 2β,4a-Dihydroxy-1-methyl-8-methylene-4aα,4bβ-gibbane-1α,10β-dicarboxylic Acid; (1α,2β,4aα,4bβ,10β)-2,4a-Dihydroxy-1-methyl-8-methylene-gibbane-1,10-dicarboxylic Acid. Grade: > 95%. CAS No. 468-44-0. Molecular formula: C19H24O5. Mole weight: 332.40.
gibberellin A4 carboxyl methyltransferase
The enzyme also methylates gibberellins A34 (80%), A9 (60%), and A3 (45%) with significant activity. Group: Enzymes. Synonyms: GAMT2; gibberellin A4 O-methyltransferase. Enzyme Commission Number: EC 2.1.1.276. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1882; gibberellin A4 carboxyl methyltransferase; EC 2.1.1.276; GAMT2; gibberellin A4 O-methyltransferase. Cat No: EXWM-1882.
Gibberellin A4-[d2]
Gibberellin A4-[d2] is an isotopic analog of Gibberellin A4, a plant growth hormone that regulates growth and differentiation of plant cells for elongation, germination and enzyme induction. Synonyms: 4a,1-(Epoxymethano)-7,9a-methanobenz[a]azulene, gibbane-1,10-dicarboxylic Acid Deriv.-d2; GA4-d2; 2β,4a-Dihydroxy-1-methyl-8-methylene-4aα,4bβ-gibbane-1α,10β-dicarboxylic Acid-d2; (1α,2β,4aα,4bβ,10β)-2,4a-Dihydroxy-1-methyl-8-methylene-gibbane-1,10-dicarboxylic Acid 1,4a-Lactone-d2. Grade: > 95%. CAS No. 84693-21-0. Molecular formula: C19H22O5D2. Mole weight: 334.41.
Gibberellin A5
Gibberellin A5. Group: Biochemicals. Alternative Names: 4a,7-Dihydroxy-1-methyl-8-methylene-4aα,4b β-Gibb-2-ene-1α,10 β-dicarboxylic Acid 1,4a-Lactone; GA5; GA5 (Gibberellin). Grades: Highly Purified. CAS No. 561-56-8. Pack Sizes: 25mg. Molecular Formula: C19H22O5, Molecular Weight: 330.37. US Biological Life Sciences.
Worldwide
Gibberellin A5
Gibberellin A5 is a plant hormone which promotes floral development but have little effect on stem elongation. Synonyms: C11871; (1R,2R,5S,8S,9S,10R,11R)-5-Hydroxy-11-Methyl-6-Methylidene-16-Oxo-15-Oxapentacyclo[9.3.2.1(5,8).0(1,10).0(2,8)]Heptadec-12-Ene-9-Carboxylic Acid; 4a,7-Dihydroxy-1-methyl-8-methylene-4aα,4bβ-Gibb-2-ene-1α,10β-dicarboxylic Acid 1,4a-Lactone; GA5. Grade: > 95%. CAS No. 561-56-8. Molecular formula: C19H22O5. Mole weight: 330.38.
Gibberellin A8. Group: Biochemicals. Alternative Names: 2 β,3 β,4a,7-Tetrahydroxy-1-methyl-8-methylene-4aα,4b β-gibbane-1α,10 β-dicarboxylic Acid 1,4a-Lactone; Dodecahydro-2,3,4a,7-tetrahydroxy-1-methyl-8-methylene-7H-7,9a-methanobenz[a]azulene-1,10-dicarboxylic Acid 1,4a-Lactone; GA8. Grades: Highly Purified. CAS No. 7044-72-6. Pack Sizes: 10mg. Molecular Formula: C19H24O7, Molecular Weight: 364.39. US Biological Life Sciences.
Worldwide
Gibberellin A9
Gibberellin A9, an influential phytohormone, serves as a ubiquitous, biologically active plant growth regulator prevalently deployed within the agricultural sectors. Synonyms: (1R,4aR,4bR,7R,9aR,10S,10aR)-1-methyl-8-methylene-13-oxododecahydro-4a,1-(epoxymethano)-7,9a-methanobenzo[a]azulene-10-carboxylic acid. Grade: 95%. CAS No. 427-77-0. Molecular formula: C19H24O4. Mole weight: 316.4.
Gibberellin A95
Gibberellin A95. Group: Biochemicals. Alternative Names: 4a,1-(Epoxymethano)-7,9a-methanobenz[a]azulene, gibb-3-ene-1,10-dicarboxylic Acid Deriv.; GA95; Gibberellin GA95; NSC 224287. Grades: Highly Purified. CAS No. 78259-50-4. Pack Sizes: 50mg. Molecular Formula: C19H22O5, Molecular Weight: 330.37. US Biological Life Sciences.
Worldwide
Gibberellin A95
Gibberellin A95 is a derivative of Gibberelic Acid. It is a stereoisomer of Gibberelin A5. Synonyms: 4a,1-(Epoxymethano)-7,9a-methanobenz[a]azulene, gibb-3-ene-1,10-dicarboxylic Acid Deriv.; GA95; NSC 224287. Grade: > 95%. CAS No. 78259-50-4. Molecular formula: C19H22O5. Mole weight: 330.38.
gibberellin A9 O-methyltransferase
The enzyme also methylates gibberellins A20 (95%), A3 (80%), A4 (69%) and A34 (46%) with significant activity. Group: Enzymes. Synonyms: GAMT1. Enzyme Commission Number: EC 2.1.1.275. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1881; gibberellin A9 O-methyltransferase; EC 2.1.1.275; GAMT1. Cat No: EXWM-1881.
gibberellin β-D-glucosyltransferase
Acts on the plant hormone gibberellin GA3 and related compounds. Group: Enzymes. Synonyms: uridine diphosphoglucose-gibberellate 7-glucosyltransferase; uridine diphosphoglucose-gibberellate 3-O-glucosyltransferase. Enzyme Commission Number: EC 2.4.1.176. CAS No. 99775-14-1,94489-97-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2401; gibberellin β-D-glucosyltransferase; EC 2.4.1.176; 99775-14-1,94489-97-1; uridine diphosphoglucose-gibberellate 7-glucosyltransferase; uridine diphosphoglucose-gibberellate 3-O-glucosyltransferase. Cat No: EXWM-2401.
Gibberellin impurity 3
Gibberellin impurity 3. Uses: For analytical and research use. CAS No. 13744-18-8. Molecular formula: C20H26O4. Mole weight: 330.42. Catalog: APB13744188.
Gibberellins A4/A7
Gibberellins A4/A7 induces stimulation of tracheid production in the terminal shoot of intact plants is mediated through an increase in the IAA level in the cambial region[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GA4+7. CAS No. 8030-53-3. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg. Product ID: HY-139351.
Gibbestatin B
It is produced by the strain of Streptomyces sp. C39. Gibbestatin B inhibits the expression of α-amylase induced by gibberellin in De-embryoned rice and barley (IC50 is 25-50 ppm, IC100 is 100-200 ppm), and has no anti-bacterial, anti-yeast and anti-fungal effects at 100 ppm (MIC, agar dilution method using bouillon agar for bacteria and Sabouraud agar for yeast and fungi). Synonyms: Antibiotic 2-11-B. CAS No. 89687-34-3. Molecular formula: C22H26O6. Mole weight: 386.44.
Gibbestatin C
It is produced by the strain of Streptomyces sp. C39. It is a bioactive substance. Gibberellin C of 200 ppm has no inhibitory effect on α-amylase. It also has no anti-bacterial, anti-yeast and anti-fungal effects at 100 ppm (MIC, agar dilution method using bouillon agar for bacteria and Sabouraud agar for yeast and fungi). Synonyms: 2-Hydroxypenyl Gibbestatin B. Molecular formula: C28H30O7. Mole weight: 478.53.
GIBH-130
GIBH-130 is an effective inhibitor of neuroinflammation. GIBH-130 significantly suppresses theIL-1βsecretion by activated microglia (IC50=3.4 nM). GIBH-13 constitutes a unique chemical probe for pathogenesis research and drug development of AD, and it also suggests microglia-based phenotypic screenings that target neuroinflammation as an effective and feasible strategy to identify novel anti-AD agents. Synonyms: (4-methyl-6-phenylpyridazin-3-yl)-(4-pyrimidin-2; -ylpiperazin-1-yl)methanone; (4-methyl-6-phenylpyridazin-3-yl)(4-(pyrimidin-2-yl)piperazin-1-yl)methanone; GIBH-130; GIBH130; GIBH 130. CAS No. 1252608-59-5. Molecular formula: C20H20N6O. Mole weight: 360.41.
Giemsa stain
Giemsa stain. Group: Biochemicals. Grades: Highly Purified. CAS No. 51811-82-6. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C14H14ClN3S. US Biological Life Sciences.
Worldwide
Giemsa Stain
Giemsa Stain. Uses: For analytical and research use. Alternative Names: Mixture of Azure II Eosinate & Methylene Blue. CAS No. 51811-82-6. Molecular formula: C14H14ClN3S. Mole weight: 291.80. Catalog: APB51811826.
Giemsa Stain
25g Pack Size. Group: Stains & Indicators. Formula: C14H14ClN3S. CAS No. 51811-82-6. Prepack ID 48872073-25g. Molecular Weight 291.8. See USA prepack pricing.
Giffonin R
Giffonin R is a natural compound isolated from the herbs of Corylus avellana. Grade: 97.5%. CAS No. 1966183-72-1. Molecular formula: C19H16O3. Mole weight: 292.334.
Gigantol
Gigantol is an orally active bibenzyl compound. Gigantol targets MYC to promote its ubiquitin-proteasomal degradation and inhibit the growth of lung cancer cells. Gigantol exerts anti-lung cancer activity by inducing ferroptosis (Ferroptosis) via the SLC7A11-GPX4 axis. Gigantol restores the sensitivity of mcr-harboring multidrug-resistant bacteria to colistin. Gigantol ameliorates carbon tetrachloride-induced liver injury by inhibiting the activation of the JNK/cPLA2/12-LOX inflammatory pathway. Gigantol promotes cholesterol metabolism and progesterone biosynthesis in Leydig cells. Gigantol can be used in studies related to diseases such as lung cancer, multidrug-resistant Gram-negative bacterial infections, and acute liver injury[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 83088-28-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N10549.
Gilmelisib
Gilmelisib is a PI3K inhibitor and antineoplastic. Synonyms: PI3K-IN-20. CAS No. 1845777-61-8. Molecular formula: C24H23ClFN5O5S. Mole weight: 547.99.
Gilsonite 12002-43-6
Gilsonite - Surface Coatings. SUPPLIERS TO BUSINESS CUSTOMERS ONLY.
North America & APAC
Gilteritinib
Gilteritinib, also known as (ASP2215, is a potent FLT3/AXL inhibitor, which showed potent antileukemic activity against AML with either or both FLT3-ITD and FLT3-D835 mutations. In invitro, among the 78 tyrosine kinases tested, ASP2215 inhibited FLT3, LTK, ALK, and AXL kinases by over 50% at 1 nM with an IC50 value of 0.29 nM for FLT3, approximately 800-fold more potent than for c-KIT, the inhibition of which is linked to a potential risk of myelosuppression. ASP2215 inhibited the growth of MV4-11 cells, which harbor FLT3-ITD, with an IC50 value of 0.92 nM, accompanied with inhibition of pFLT3, pAKT, pSTAT5, pERK, and pS6. ASP2215 decreased tumor burden in bone marrow and prolonged the survival of mice intravenously transplanted with MV4-11 cells. ASP2215 may have potential use in treating AML. Synonyms: ASP2215; ASP-2215; ASP 2215; Xospata; Gilteritinibum; 6-Ethyl-3-((3-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)-amino)-5-((tetrahydro-2H-pyran-4-yl)amino)pyrazine-2-carboxamide; 6-Ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-2-pyrazinecarboxamide. Grade: ≥95%. CAS No. 1254053-43-4. Molecular formula: C29H44N8O3. Mole weight: 552.71.
Gilteritinib
Gilteritinib (ASP2215) is a potent and ATP-competitive FLT3/AXL inhibitor with IC50s of 0.29 nM/0.73 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASP2215. CAS No. 1254053-43-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-12432.
Gilteritinib-d8
Gilteritinib-d8 is deuterium labeled Gilteritinib. Gilteritinib (ASP2215) is a potent and ATP-competitive FLT3/AXL inhibitor with IC50s of 0.29 nM/0.73 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASP2215-d8. CAS No. 2377109-74-3. Pack Sizes: 1 mg. Product ID: HY-12432S1.
Gilteritinib hemifumarate
Gilteritinib hemifumarate is a medication used to treat acute myeloid leukemia (AML), particularly in patients with specific genetic mutations in the FLT3 gene (FMS-like tyrosine kinase 3). Gilteritinib is a tyrosine kinase inhibitor that specifically targets and inhibits the FLT3 receptor, which is often mutated and overactive in certain types of AML. By inhibiting FLT3, gilteritinib helps to reduce the proliferation of leukemia cells. Synonyms: Gilteritinib fumarate; ASP-2215 hemifumarate; 2-Pyrazinecarboxamide, 6-ethyl-3-((3-methoxy-4-(4-(4-methyl-1-piperazinyl)-1-piperidinyl)phenyl)amino)-5-((tetrahydro-2H-pyran-4-yl)amino)-, (2E)-2-butenedioate (2:1); 6-Ethyl-3-((3-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)-5-((tetrahydro-2H-pyran-4-yl)amino)pyrazine-2-carboxamide hemifumarate. Grade: ≥95%. CAS No. 1254053-84-3. Molecular formula: C29H44N8O3.1/2C4H4O4. Mole weight: 1221.52.
Gilteritinib hemifumarate
Gilteritinib (ASP2215) hemifumarate is a potent and ATP-competitive FLT3/AXL inhibitor with IC50 of 0.29 nM/0.73 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASP2215 hemifumarate. CAS No. 1254053-84-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12432A.
Gilteritinib (Standard)
Gilteritinib (Standard) is the analytical standard of Gilteritinib. This product is intended for research and analytical applications. Gilteritinib (ASP2215) is a potent and ATP-competitive FLT3/AXL inhibitor with IC50s of 0.29 nM/0.73 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASP2215 (Standard). CAS No. 1254053-43-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12432R.
Gilvetmab
Gilvetmab is a potent caninized anti-PD-1 monoclonal antibody. Gilvetmab blocks the interaction between PD-1 and its ligand PD-L1/L2. Gilvetmab can be used in malignant melanoma and mast cell tumor research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1808081-43-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99641.
Gilvocarcin E
It is produced by the strain of Streptomyces gilvotanareus, Str. anandii. It has anti-gram-positive bacterial activity and can inhibit sarcoma 180 and P388 leukemia cells. Synonyms: 8-Ethyl-4-(6-deoxy-α-L-galactofuranosyl)-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one; Anandimycin C; Toromycin C; dihydrotoromycin; 4-Fucofuranosyl-1-hydroxy-10,12-dimethoxy-8-ethyl-6H-benzo(d)naphtho(1,2b)pyran-6-one; 1,4-Anhydro-6-deoxy-1-(8-ethyl-1-hydroxy-10,12-dimethoxy-6-oxo-6H-benzo[d]naphtho[1,2-b]pyran-4-yl)hexitol. CAS No. 80937-34-4. Molecular formula: C27H28O9. Mole weight: 496.50.
Gilvocarcin M
It is produced by the strain of Streptomyces gilvotanareus, Str. anandii. It has anti-gram-positive bacterial activity and can inhibit sarcoma 180 and P388 leukemia cells. Synonyms: 6H-Benzo(d)naphtho(1,2-b)pyran-6-one, 4-(6-deoxy-alpha-galactofuranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl-; 4-(6-Deoxy-α-L-galactofuranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl-6H-benzo[d]naphtho[1,2-b]pyran-6-one; Anandimycin B; ToroMycin B; Antibiotic 1072A. Grade: >95% by HPLC. CAS No. 77879-89-1. Molecular formula: C26H26O9. Mole weight: 482.48.
Gilvocarcin V
Antibiotic. Antitumor compound. Weakly active against Gram-positive bacteria and fungi. Mediates a unique cross-linking reaction between DNA and histone H3 by light. Single strand scission and covalent binding to DNA after photoactivation. Source:Streptomyces sp. Gö 3592. Group: Biochemicals. Alternative Names: 4-(6-Deoxy-α-D-galactofuranosyl)-8-ethenyl-1-hydroxy-10,12-dimethoxy-6H-benzo[d]naphtho[1,2-b]pyran-6-one; Antibiotic 1072B; NSC 338943; NSC 348115. Grades: Highly Purified. CAS No. 77879-90-4. Pack Sizes: 100ug, 250ug, 1mg. Molecular Formula: C??H??O?. US Biological Life Sciences.