A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Glafenine is a non-steroidal analgesic agent, shows significant antiinflammatory activity. Uses: Wdely used for the treatment of pains of various origins. Synonyms: 2,3-dihydroxypropyl 2-[(7-chloroquinolin-4-yl)amino]benzoate; 1-Glyceryl N-(7-chloro-4-quinolyl)anthranilate. Grades: ≥98%. CAS No. 3820-67-5. Molecular formula: C19H17ClN2O4. Mole weight: 372.80.
Glafenine hydrochloride
Glafenine hydrochloride, an anthranilic acid derivative, is a non-narcotic analgesic and non-steroidal anti-inflammatory drug. It is an ABCG2 inhibitor (IC50 = 3.2 μM). Synonyms: 2,3-dihydroxypropyl 2-[(7-chloroquinolin-4-yl)amino]benzoate;hydrochloride; Glafenine (hydrochloride). CAS No. 65513-72-6. Molecular formula: C19H18Cl2N2O4. Mole weight: 409.26.
Glafenine hydrochloride
Glafenine hydrochloride is a non-narcotic analgesic and non-steroidal anti-inflammatory drug. It is an ABCG2 inhibitor with an IC 50 of 3.2 μM. Glafenine can also antagonize the misfolding of SLC4A11 protein [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Glafenin hydrochloride. CAS No. 65513-72-6. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-B1153A.
Glasdegib
Glasdegib (PF-04449913) is a potent and orally bioavailable smoothened inhibitor. Glasdegib (PF-04449913) binds to human SMO (amino acids 181-787) with an IC 50 of 4 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PF-04449913. CAS No. 1095173-27-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16391.
Glasdegib
Glasdegib is an orally bioavailable small-molecule inhibitor of the Hedgehog (Hh) signaling pathway that binds to Smoothened (Smo) and inhibits signal transduction. It has been shown to attenuate leukemia stem cell self-renewal and cell cycle progression in primary acute myeloid leukemia cells and in an in vivo Drosophila model. Synonyms: PF-04449913; PF 04449913; 1-[(2R,4R)-2-(1H-benzimidazol-2-yl)-1-methylpiperidin-4-yl]-3-(4-cyanophenyl)urea. Grades: >98%. CAS No. 1095173-27-5. Molecular formula: C21H22N6O. Mole weight: 374.44.
Glatiramer acetate is an immunomodulator drug currently used to treat multiple sclerosis. It is a random polymer of four amino acids found in myelin basic protein, namely L-glutamic acid, L-lysine, L-alanine, and L-tyrosine. Synonyms: Copaxone; Copolymer 1; Copolymer-1. CAS No. 147245-92-9. Molecular formula: C25H45N5O13. Mole weight: 623.657.
Glatiramer acetate
Glatiramer acetate, a synthetic analogue of myelin basic protein and an immunomodulating agent, inhibits Experimental autoimmune encephalomyelitis (EAE), and can be used for the research of multiple sclerosis. Glatiramer acetate exhibits strong and promiscuous binding to MHC molecules and consequent competition with various myelin antigens for their presentation to T cells. A further aspect of its action is potent induction of specific suppressor cells of the T helper 2 (Th2) type that migrate to the brain and lead to in situ bystander suppression [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 147245-92-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109520.
Glatiramer Acetate
Glatiramer Acetate. Uses: For analytical and research use. Group: Building blocks. Alternative Names: L-Lysine, polymer with L-alanine, L-glutamic acid and L-tyrosine, acetate (salt) (9CI), TV 5010, Copaxone, Cop 1, Glatiramer acetate, Cop 1 (polyamide), Probioglat, L-Tyrosine, polymer with L-alanine, L-glutamic acid and L-lysine, acetate (salt) (9CI), L-Alanine, polymer with L-glutamic acid, L-lysine and L-tyrosine, acetate (salt) (9CI), Copolymer 1, Escadra, Hangzhou, Protiramer, L-Glutamic acid peptide with L-alanine, L-lysine and L-tyrosine, acetate (salt), Natco,L-Glutamic acid, polymer with L-alanine, L-lysine and L-tyrosine, acetate (salt), Polimunol. CAS No. 147245-92-9. Molecular Formula: ( (C9H11NO3)mon (C3H7NO2)mon (C6H14N2O2)mon (C5H9NO4)mon)ran. C2H4O2. Mole Weight: 623.65. Catalog: APS147245929. Format: Neat.
Glatiramer Acetate
Glatiramer acetate is a random basic synthetic copolymer of L-alanine, L-lysine, l-glutamic acid and L-tyrosine in a molar ratio of 6:1.9:4.7:1. Glatiramer acetate is an immunomodulator used in treatment of multiple sclerosis. A representative lot had an average molecular weight of 4600 amu. Group: Biochemicals. Alternative Names: L-Alanine polymer with L-Glutamic Acid L-Lysine L-Tyrosine Acetate ; L-Tyrosine polymer with L-Alanine L-Glutamic Acid L-Lysine Acetate; 511: PN: WO2010103292 PAGE: 64 claimed sequence; Cop 1; Copaxone; Copolymer 1; L-Glutamic Acid peptide with L-Alanine L-Lysine L-Tyrosine Acetate Salt; Protiramer; TV 5010. Grades: Highly Purified. CAS No. 147245-92-9. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C?H??NO?; C? H??N?O?; C?H?NO?; C?H?NO?. US Biological Life Sciences.
Glaucine (O,O-Dimethylisoboldine) is an alkaloid isolated from Glaucium flavum with antitussive, bronchodilation and anti-inflammatory properties. Glaucine is a selective and orally active phosphodiesterase 4 (PDE4) inhibitor with Kis of 3.4 μM in human bronchus and polymorphonuclear leukocytes. Glaucine is also a non-selective α-adrenoceptor antagonist, a Ca2+ entry blocker, and a weak dopamine D1 and D2 receptor antagonist. Glaucine has antioxidative and antiviral activities. Group: Inhibitors. Alternative Names: 1,2,9,10-Tetramethoxy-6a-alpha-aporphine. CAS No. 475-81-0. Molecular formula: C21H25NO4. Mole weight: 355.4. Purity: 95%+. Catalog: ACM475810.
Glaucine
Glaucine (O,O-Dimethylisoboldine) is an alkaloid extracted from Glaucium flavum that possesses various activities, including cough relief, bronchodilation, anti-inflammatory effects, analgesia, antipyretic properties, and anticancer effects. Glaucine acts as a selective and orally active inhibitor of phosphodiesterase 4 ( PDE4 ), with a K i of 3.4 μM in human bronchial tissues and polymorphonuclear leukocytes. Glaucine induces relaxation of human isolated bronchi by antagonizing calcium channels. Additionally, Glaucine inhibits the activation of NF-κB , leading to a reduction in the expression of the MMP-9 gene, thereby suppressing the migration and invasion of breast cancer cells. Therefore, Glaucine holds potential for research in asthma and breast cancer [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Natural products. Alternative Names: O,O-Dimethylisoboldine; S-(+)-Glaucine; NSC 34396. CAS No. 475-81-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N3945.
Glaucocalyxin A
Glaucocalyxin A, an ent-kauranoid diterpene from Rabdosia japonica var., induces apoptosis in osteosarcoma by inhibiting nuclear translocation of Five-zinc finger Glis 1 (GLI1) via regulating PI3K/Akt signaling pathway. Glaucocalyxin A has antitumor effect [1]. Uses: Scientific research. Group: Natural products. CAS No. 79498-31-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-N2112.
Glaucocalyxin A
Glaucocalyxin A. Group: Biochemicals. Alternative Names: Leukamenin F; Wangzaozin B. Grades: Plant Grade. CAS No. 79498-31-0. Pack Sizes: 10mg. Molecular Formula: C20H28O4, Molecular Weight: 332.434. US Biological Life Sciences.
Worldwide
Glaucocalyxin A Liposome
Glaucocalyxin A is a diterpenoid component that has strong antitumor activity against different leukemia cell lines. This product is a pre-formulated liposome with glaucocalyxin A. It is only for research purposes. Group: Drug-loaded liposome. Categories: Glaucocalyxin A (GLA).
Glaucocalyxin B
Glaucocalyxin B is a diterpenoid isolated from Rabdosia japonica with anti-inflammatory effects. Synonyms: HY-N2113. Grades: 98%. CAS No. 80508-81-2. Molecular formula: C22H30O5. Mole weight: 374.47.
The enzyme is involved in the biosynthesis of the exopolysaccharide xanthan. Group: Enzymes. Synonyms: GumI. Enzyme Commission Number: EC 2.4.1.251. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2481; GlcA-β-(1?2)-D-Man-α-(1?3)-D-Glc-β-(1?4)-D-Glc-α-1-diphospho-ditrans,octacis-undecaprenol 4-β-mannosyltransferase; EC 2.4.1.251; GumI. Cat No: EXWM-2481.
GlcNAc-1-phosphate uridyltransferase from Campylobacter jejuni, Recombinant
N-Acetylglucosamine-1-phosphate uridyltransferase (GlmU), a bifunctional enzyme exclusive to prokaryotes, belongs to the family of sugar nucleotidyltransferases (SNTs). The enzyme binds GlcNAc-1-P and UTP, and catalyzes a uridyltransfer reaction to synthesize UDP-GlcNAc, an important precursor for cell-wall biosynthesis. Group: Enzymes. Synonyms: N-Acetylglucosamine-1-phosphate uridyltransferase; GlmU; EC 2.3.1.157. Enzyme Commission Number: EC 2.3.1.157. Purity: min 95% by SDS-PAGE. GlcNAc1-phosphate uridyltransferase. Source: E. coli. Species: Campylobacter jejuni. N-Acetylglucosamine-1-phosphate uridyltransferase; GlmU; EC 2.3.1.157; GlcNAc1-P Uridyltransferase. Cat No: NATE-1492.
GlcNAc1-phosphate uridyltransferase from E. coli K-12, Recombinant
N-Acetylglucosamine-1-phosphate uridyltransferase (GlmU), a bifunctional enzyme exclusive to prokaryotes, belongs to the family of sugar nucleotidyltransferases (SNTs). The enzyme binds GlcNAc-1-P and UTP, and catalyzes a uridyltransfer reaction to synthesize UDP-GlcNAc, an important precursor for cell-wall biosynthesis. Group: Enzymes. Synonyms: N-Acetylglucosamine-1-phosphate uridyltransferase; GlmU; EC 2.3.1.157. Enzyme Commission Number: EC 2.3.1.157. Purity: min 95% by SDS-PAGE. GlcNAc1-phosphate uridyltransferase. Mole weight: 25 kDa. Source: E. coli. Species: E. coli K-12. N-Acetylglucosamine-1-phosphate uridyltransferase; GlmU; EC 2.3.1.157; GlcNAc1-P Uridyltransferase. Cat No: NATE-1482.
GlcNAc-1-phosphate uridyltransferase from Human, Recombinant
N-Acetylglucosamine-1-phosphate uridyltransferase (GlmU), a bifunctional enzyme exclusive to prokaryotes, belongs to the family of sugar nucleotidyltransferases (SNTs). The enzyme binds GlcNAc-1-P and UTP, and catalyzes a uridyltransfer reaction to synthesize UDP-GlcNAc, an important precursor for cell-wall biosynthesis. Group: Enzymes. Synonyms: N-Acetylglucosamine-1-phosphate uridyltransferase; GlmU; EC 2.3.1.157. Enzyme Commission Number: EC 2.3.1.157. CAS No. 9023-06-7;9031-91-8. Purity: min 95% by SDS-PAGE. GlcNAc1-phosphate uridyltransferase. Source: E. coli. Species: Human. N-Acetylglucosamine-1-phosphate uridyltransferase; GlmU; EC 2.3.1.157; GlcNAc1-P Uridyltransferase. Cat No: NATE-1500.
GlcNPhth[346Ac]b(1-3)Gal[246Bn]-b-MP is an innovative compound, finding its applications in studying aberrant cellular proliferation. By selectively antagonizing intricate molecular cascades implicated in the advancement of neoplastic conditions, it emerges as a potent inhibitory compound. Synonyms: 4-Methoxyphenyl 3-O-(3,4,6-Tri-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-2,4,6-tri-O-benzyl-b-D-galactopyranoside. Molecular formula: C54H55NO16. Mole weight: 974.01.
glecaprevir
Glecaprevir is a suppressive agent of hepatitis C virus (HCV). Glecaprevir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 4.09 μM. Uses: The treatment of hepatitis c virus (hcv) infection. Synonyms: ABT 493; (3aR, 7S, 10S, 12R, 21E, 24aR) -7-tert-butyl-N-[ (1R, 2R) -2- (difluoromethyl) -1-{[ (1-methylcyclopropyl) sulfonyl]carbamoyl}cyclopropyl]-20, 20-difluoro-5, 8-dioxo-2, 3, 3a, 5, 6, 7, 8, 11, 12, 20, 23, 24a-dodecahydro-1H, 10H-9, 12-methanocyclopenta[18, 19][1, 10, 17, 3, 6]trioxadiazacyclononadecino[11, 12-b]quinoxaline-10-carboxamide. Grades: 98%. CAS No. 1365970-03-1. Molecular formula: C38H46F4N6O9S. Mole weight: 838.87.
Glecaprevir
Glecaprevir is a novel HCV NS3/4A protease inhibitor, with IC 50 values ranging from 3.5 to 11.3 nM. Glecaprevir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 4.09 μM [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-493. CAS No. 1365970-03-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17634.
Glecirasib
Glecirasib (Compound 1-2; JAB-21822) is an orally active and potent inhibitor of KRAS G12C. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. Glecirasib has the potential for the research of KRAS G12C-mediated cancer [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JAB-21822; KRAS G12C inhibitor 36. CAS No. 2657613-87-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-143589.
Glembatumumab
Glembatumumab is a fully human IgG2 monoclonal antibody directed against the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma. Glembatumumab can be coupled to the microtubule inhibitor monomethyl auristatin E to form glembatumumab vedotin. Glembatumumab vedotin is an antibody-agent coupling ( ADC ) with antitumor activity [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 1020264-78-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99205.
Glembatumumab
Glembatumumab is a human IgG2 monoclonal antibody directed against the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma. Glembatumumab can be linked to monomethyl auristatin E (MMAE) to form Glembatumumab vedotin, an ADC for cancer therapy. Synonyms: Anti-GPNMB. CAS No. 1020264-78-1.
Glembatumumab vedotin
Glembatumumab vedotin (CDX-011) is an ADC ( antibody-drug conjugates (ADCs) ) comprising a fully human IgG2 monoclonal antibody (CR011) directed against glycoprotein NMB (GPNMB) and conjugated to the potent tubulinbinding cytotoxic agent MMAE via a protease-sensitive vc linker. Glembatumumab vedotin has potent anticancer effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CDX-011; CR011-vcMMAE. CAS No. 1182215-65-1. Pack Sizes: 1 mg; 5 mg. Product ID: HY-141604.
Glepaglutide
Glepaglutide, a long-acting GLP-2 analogue, is a potent GLP-2R agonist. Glepaglutide reduces faecal output and increases intestinal absorption. Glepaglutide alleviates small intestinal inflammation. Glepaglutide can be used in the research of inflammatory bowel disease (IBD) and Crohn's disease. Synonyms: ZP1848. CAS No. 914009-86-2. Molecular formula: C197H325N53O55. Mole weight: 4316.08.
Glesatinib
Glasatinib (MGCD265) is a dual MET/SMO inhibitor. Glesatinib is a small molecule, multi-target tyrosine kinase inhibitor with potential anti-tumor activity, which can antagonize P-glycoprotein (P-gp)-mediated multidrug resistance (MDR) in non-small cell lung cancer (NSCLC). Synonyms: MGCD-265; MGCD 265; MGCD265. Grades: ≥98% by HPLC. CAS No. 936694-12-1. Molecular formula: C31H27F2N5O3S2. Mole weight: 619.7.
Glesatinib hydrochloride
Glesatinib hydrochloride (MGCD265 hydrochloride) is an orally active, potent MET/SMO dual inhibitor. Glesatinib hydrochloride, a tyrosine kinase inhibitor, antagonizes P-glycoprotein (P-gp) mediated multidrug resistance (MDR) in non-small cell lung cancer (NSCLC) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MGCD265 hydrochloride. CAS No. 1123838-51-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19642A.
Glesatinib hydrochloride
The hydrochloride salt form of Glesatinib, an inhibitor of tyrosine kinase, could be effectively targeting tumors that are driving to grow through MET and AXL receptor. It seems to be more common in non-small cell lung cancer and it is still under Phase I. Uses: The hydrochloride salt form of glesatinib could be effectively targeting tumors that are driving to grow through met and axl receptor. Synonyms: MGCD265 hydrochloride; MGCD-265 hydrochloride; MGCD 265 hydrochloride. Grades: 98%. CAS No. 1123838-51-6. Molecular formula: C31H27ClF2N5O3S2X. Mole weight: 655.16.
Gliadin p31-43
Gliadin p31-43 is an undigested gliadin peptide. Gliadin p31-43 induces an innate immune response in the intestine and interferes with endocytic trafficking. Gliadin p31-43 can be used for celiac disease research [1] [2]. Uses: Scientific research. Group: Peptides. CAS No. 176326-01-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P3151.
Gliadins
Gliadins (Tyrosyl prolyl glutaminyl prolyl glutamine) comprise a family of glutamine- and proline-rich monomeric proteins that plays an role in autoimmune disease, such as celiac disease [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Tyrosyl prolyl glutaminyl prolyl glutamine. CAS No. 9007-90-3. Pack Sizes: 100 mg. Product ID: HY-W355779.
Gliadorphin-7
Gliadorphin-7, an opioid peptide, is formed during the digestion of the gliadin component of the gluten protein. Elevated concentration of gliadorphin-7 due to inadequate proteolysis has been linked to autism, schizophrenia, and celiac disease. Synonyms: α/β-Gliadin (43-49); H-Tyr-Pro-Gln-Pro-Gln-Pro-Phe-OH; L-tyrosyl-L-prolyl-L-glutaminyl-L-prolyl-L-glutaminyl-L-prolyl-L-phenylalanine; alpha-gliadin (43-49); GD-7; Prolamin (43-49); Gluteomorphin; Gliadorphin. Grades: ≥95%. CAS No. 107936-65-2. Molecular formula: C43H57N9O11. Mole weight: 875.98.
Gliamilide
Gliamilide is a high-potency Sulfonated urea hypoglycemic agent. Uses: Gliamilide is used as a hypoglycemic agent. Synonyms: CP-27,634; CP 27,634; CP27,634; endo-1- ( (4- (2- (2-Methoxynicotinamido) ethyl) piperidino) sulfonyl) -3- (5-norbornen-2-ylmethyl) urea. Grades: 98%. CAS No. 51876-98-3. Molecular formula: C23H33N5O5S. Mole weight: 491.61.
Glibenclamide
Glibenclamide (Glyburide) is an orally active ATP-sensitive K + channel ( K ATP ) inhibitor and can be used for the research of diabetes and obesity [1]. Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of K ATP and inhibits the cystic fibrosis transmembrane conductance regulator protein ( CFTR ) [3]. Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability [4]. Glibenclamide can induce autophagy [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Glyburide. CAS No. 10238-21-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-15206.
Glibenclamide
Glibenclamide. Group: Biochemicals. Grades: Purified. CAS No. 10238-21-8. Pack Sizes: 100mg. US Biological Life Sciences.
Cell-permeable. An anti-diabetic agent. ATP-sensitive potassium channel (KATP) blocker. Inhibits KATP currents in the pancreatic beta cells causing an increase in intracellular Ca2+ and insulin secretion. Group: Biochemicals. Grades: Highly Purified. CAS No. 10238-21-8. Pack Sizes: 500mg, 1g. US Biological Life Sciences.
Worldwide
Glibenclamide EP Impurity B
Glibenclamide EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Glyburide USP Related Compound B; methyl (4- (2- (5-chloro-2-methoxybenzamido) ethyl) phenyl) sulfonylcarbamate. CAS No. 21165-77-5. Molecular Formula: C18H19ClN2O6S. Mole Weight: 426.87. Catalog: APB21165775.
Glibenclamide impurity 1
Glibenclamide impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2191-62-0. Molecular Formula: C17H25N3O4S. Mole Weight: 367.46. Catalog: APB2191620.
Glibenclamide impurity 10
Glibenclamide impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 151890-69-6. Molecular Formula: C19H21ClN2O6S. Mole Weight: 440.9. Catalog: APB151890696.
Glibenclamide impurity 6
Glibenclamide impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 33924-49-1. Molecular Formula: C16H16ClNO2. Mole Weight: 289.76. Catalog: APB33924491.
Glibenclamide impurity 9 (5-Chloro-2-methoxybenzoic acid). Uses: For analytical and research use. Group: Impurity standards. CAS No. 3438-16-2. Molecular Formula: C8H7ClO3. Mole Weight: 186.59. Catalog: APB3438162.
Glibenclamide Impurity B
Glibenclamide Impurity B is an impurity in the synthesis of Gyburide. Synonyms: Methyl {{4-{2- [ (5-chloro-2-methoxybenzoyl) amino] ethyl}phenyl}sulfonyl}carbamate; N-[[4-[2-[ (5-Chloro-2-methoxybenzoyl) amino]ethyl]phenyl]sulfonyl]carbamic Acid Methyl Ester; [[4-[2-[ (5-Chloro-2-methoxybenzoyl) amino]ethyl]phenyl]sulfonyl]carbamic Acid Methyl. Grades: > 95%. CAS No. 21165-77-5. Molecular formula: C18H19ClN2O6S. Mole weight: 426.88.
Glibenclamide potassium salt
Glibenclamide potassium salt is a salt form of Glibenclamide, a KATP channel blocker used for the treatment of type 2 diabetes. Glibenclamide binds to and inhibits the sulfonylurea receptor 1 (SUR1), the regulatory subunit of the ATP-sensitive potassium channels (KATP) in pancreatic β cells. Uses: Antidiabetic. Synonyms: Glibenclamide potassium salt; Glyburide potassium salt; 23047-14-5; dipotassium; 5-chloro-N-[2-[4-[ (N-cyclohexyl-C-oxidocarbonimidoyl) sulfamoyl]phenyl]ethyl]-2-methoxybenzenecarboximidate; E99010; 5-chloro-N- (4- (N- (cyclohexylcarbamoyl) sulfamoyl) phenethyl) -2-methoxybenzamide potassium. Grades: 99%. CAS No. 23047-14-5. Molecular formula: C23H26ClK2N3O5S. Mole weight: 570.18.
Glibornuride
Glibornuride is a blocker of ATP-sensitive K + channels ( K ATP channel ) with a pK i of 5.75 [1]. Antidiabetic agent [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 26944-48-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17451.
Glibornuride is an anti-diabetic drug from the group of sulfonylureas. It has been shown to antagonize the relaxant response to the K+ channel opener cromakalim and produce airway smooth muscle relaxation. It is associated with lactic acidosis and hypoglycemia in patients with type 2 diabetes melitus. Uses: Anti-diabetic drug. Synonyms: 1-[(1S,2S,3R,4R)-3-hydroxy-4,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl]-3-(4-methylphenyl)sulfonylurea. Grades: > 98%. CAS No. 26944-48-9. Molecular formula: C18H26N2O4S. Mole weight: 366.476.