A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
GLP-1 is a potent insulin secretagogue that has multiple synergetic effects on the glucose-dependent insulin secretion pathways of the beta-cell. Alternative Names: GLP-1 trifluoroacetate salt; Glucagon-like peptide 1 trifluoroacetate salt; H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2.TFA.
GLP-2 (1-33) (human)
GLP-2 (human) is an endogenous peptide that acts as an intestinal epithelium-specific growth factor. It stimulates cell proliferation and inhibits apoptosis, and also modulates intestinal glucose transport, food intake, and gastric acid secretion. Alternative Names: Glucagon-like peptide 2 (human); GLP-2 (human); GLP 2 (human). Grades: >98%. CAS No. 223460-79-5. Molecular formula: C165H254N44O55S. Mole weight: 3766.1.
GLP-2(1-33)(human)
GLP-2(1-33) (human) is an enteroendocrine hormone which can bind to the GLP-2 receptor and stimulate the growth of intestinal epithelium. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GLP-2 (human); Glucagon-like peptide 2 (human). CAS No. 223460-79-5. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P1024.
GLP-2 (1-34) (human)
GLP-2 (1-34) (human) is a human-derived mimic of glucagon-like peptide 2 employed in studying gastrointestinal disorders such as short bowel syndrome (SBS). Alternative Names: Preproglucagon (146-179) (human); H-His-Ala-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-Arg-OH; L-histidyl-L-alanyl-L-alpha-aspartyl-glycyl-L-seryl-L-phenylalanyl-L-seryl-L-alpha-aspartyl-L-alpha-glutamyl-L-methionyl-L-asparagyl-L-threonyl-L-isoleucyl-L-leucyl-L-alpha-aspartyl-L-asparagyl-L-leucyl-L-alanyl-L-alanyl-L-arginyl-L-alpha-aspartyl-L-phenylalanyl-L-isoleucyl-L-asparagyl-L-tryptophyl-L-leucyl-L-isoleucyl-L-glutaminyl-L-threonyl-L-lysyl-L-isoleucyl-L-threonyl-L-alpha-aspartyl-L-arginine. Grades: 95%. CAS No. 99120-49-7. Molecular formula: C171H266N48O56S1. Mole weight: 3922.29.
GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC50=5.8 nM)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 275801-62-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P2625.
GLP-26
GLP-26 is a HBV capsid assembly modulators (CAM), inhibits HBV DNA replication in Hep AD38 system (IC50=3 nM), and reduces cccDNA by >90% at 1 μM.GLP-26 disrupts the encapsidation of pre-genomic RNA, causes nucleocapsid disassembly and reduces cccDNA pools[1]. GLP-26 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2133017-36-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124614.
GLP-2 (rat)
GLP-2 (rat) is an endogenous peptide that acts as an intestinal epithelium-specific growth factor. It stimulates cell proliferation and inhibits apoptosis, and also modulates intestinal glucose transport, food intake, and gastric acid secretion. Alternative Names: Preproglucagon (146-178) (rat); H-His-Ala-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Thr-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-OH; Glucagon-like Peptide 2 (rat); L-histidyl-L-alanyl-L-alpha-aspartyl-glycyl-L-seryl-L-phenylalanyl-L-seryl-L-alpha-aspartyl-L-alpha-glutamyl-L-methionyl-L-asparagyl-L-threonyl-L-isoleucyl-L-leucyl-L-alpha-aspartyl-L-asparagyl-L-leucyl-L-alanyl-L-threonyl-L-arginyl-L-alpha-aspartyl-L-phenylalanyl-L-isoleucyl-L-asparagyl-L-tryptophyl-L-leucyl-L-isoleucyl-L-glutaminyl-L-threonyl-L-lysyl-L-isoleucyl-L-threonyl-L-aspartic acid. Grades: ≥95%. CAS No. 195262-56-7. Molecular formula: C166H256N44O56S. Mole weight: 3796.17.
Glp-Asn-Pro-AMC
Glp-Asn-Pro-AMC is an inhibitor of thyrotropin-releasing hormone degrading enzyme (TRH-DE) with a Ki value of 0.97 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 291752-43-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P10485.
GLPG0187
GLPG0187 is a broad spectrum integrin receptor antagonist with antitumor activity; inhibits αvβ1-integrin with an IC50 of 1.3 nM[1]. GLPG0187 inhibits migrasome biogenesis without cytotoxicity[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1320346-97-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100506.
GLPG-0187
GLPG-0187 is a small molecule integrin receptor antagonist (IRA) with nanomolar affinity for the RGD-integrin receptors αvβ1, αvβ3, αvβ5, αvβ6 and α5β1 (IC50s = 1.2-3.7 nM). Integrin receptors are expressed on the surface of tumor vessel endothelial cells and some types of cancer cells, and play a crucial role in endothelial cell adhesion and migration. This compound shows an inhibitory activity of angiogenesis, bone-resorption and tumor, which is hopefully used as an anticancer drug. Uses: An integrin receptor antagonist (ira) can be used as an anticancer drug. Alternative Names: GLPG0187; GLPG 0187; GLPG-0187; UNII-43A5P87Z4T; 43A5P87Z4T; SCHEMBL2372722; CHEMBL3319236; (2S)-3-[[2,5-dimethyl-6-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)piperidin-1-yl]pyrimidin-4-yl]amino]-2-[(4-methoxyphenyl)sulfonylamino]propanoic acid. Grades: ≥98 %. CAS No. 1320346-97-1. Molecular formula: C29H37N7O5S. Mole weight: 595.719.
GLPG0259
GLPG0259 is a ATP-competitive inhibitor of MAPK-activated protein kinase 5 (MK5) with oral activity. GLPG0259 reduces inflammation and bone destruction in a mouse model of collagen-induced arthritis. GLPG0259 also inhibited the metastasis of prostate cancer (PCa) cells[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 959754-85-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-136990.
GLPG0492
GLPG0492 is an orally active, non-steroidal selective androgen receptor modulator. GLPG0492 exerts functional transactivation by binding to the ligand-binding domain of the receptor, exhibiting preferential partial agonist activity in muscle and bone tissues with low activity in reproductive tissues. GLPG0492 effectively counteracts muscle atrophy-related pathways, significantly enhances muscle strength, maintains motor ability, reduces fibrosis and improves electrophysiological parameters. GLPG0492 prevents immobilization-induced muscle atrophy and regulates muscle mass homeostasis, serving as a valuable tool compound for studies on Duchenne muscular dystrophy, muscle loss and various types of disuse musculoskeletal atrophy[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1215085-92-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18102.
GLPG0634 analog
GLPG0634 analog (Compoun 176) is a broad spectrum JAK inhibitor with IC50 values of <100 nM against JAK1, JAK2 and JAK3[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1206101-20-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-13961.
GLPG0974
GLPG0974 is a free fatty acid receptor-2 (FFA2/GPR43) antagonist with an IC50 of 9 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1391076-61-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12940.
GLPG1205
GLPG1205 is potent, selective and orally active GPR84 (a G-protein-coupled receptor) antagonist with a favorable PK/PD profile. GLPG1205 has anti-inflammatory activity and is used for the treatment of pulmonary fibrosis[1][2]. GLPG1205 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 1445847-37-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135303.
GLPG-1690
GLPG-1690, an imidazopyridine derivative, has been found to be a selective autotaxin inhibitor that could probably be effective as an anti-inflammatory agent and is under Phase II trial against Idiopathic pulmonary fibrosis (IPF). Alternative Names: Ziritaxestat; GLPG 1690; GLPG1690; 2-((2-ethyl-6-(4-(2-(3-hydroxyazetidin-1-yl)-2-oxoethyl)piperazin-1-yl)-8-methylimidazo[1,2-a]pyridin-3-yl)(methyl)amino)-4-(4-fluorophenyl)thiazole-5-carbonitrile. Grades: >98%. CAS No. 1628260-79-6. Molecular formula: C30H33FN8O2S. Mole weight: 588.71.
GLPG1837
GLPG1837 is a potent and reversible CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABBV-974. CAS No. 1654725-02-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111099.
GLPG2938
GLPG2938 is a potent and selective S1P2 antagonist. GLPG2938 can be used for the research of idiopathic pulmonary fibrosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2130996-00-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139310.
GLPG3312
GLPG3312 (Compound 28) is an orally active SIK inhibitor with IC50 values of 2.0 nM, 0.7 nM and 0.6 nM for SIK1, SIK2 and SIK3, respectively. GLPG3312 exhibits anti-inflammatory and immunomodulatory activity in vitro on human primary myeloid cells and in vivo in mouse models. GLPG3312 has good oral bioavailability and can be used for research on inflammatory and immune diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2340388-72-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157442.
GLPG3970
GLPG3970 (compound 88) is a first-in-class SIK2/SIK3 inhibitor. GLPG3970 can be used for the research of inflammation and autoimmune disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2403733-82-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-150203.
GLPG4970
GLPG4970 is a potent, selective and orally active salt-inducible kinase 2/3 (SIK2/SIK3) dual inhibitor with IC50 values of 0.3 nM and 0.7 nM. GLPG4970 has weak inhibition of hERG channel with an IC50 of 29 μM. GLPG4970 can decrease TNFα release and increase IL-10 release GLPG4970 can be used for the researches of inflammation and immunology, such as colitis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3114869-49-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-175479.
GLS1 Inhibitor-1
GLS1 Inhibitor-1 (Compound 27) is an orally active inhibitor for glutaminase 1 (GLS1) with an IC50 of 0.021 μM. GLS1 Inhibitor-1 inhibits the proliferation of PC-3 with an IC50 of 0.3 nM. GLS1 Inhibitor-1 exhibits antitumor efficacy against NCI-H1703 with GI50 of 0.011 μM. GLS1 Inhibitor-1 exhibits moderate pharmacokinetic characteristics[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1832646-52-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-136704.
Glu13, Exendin-4
Glu13, Exendin-4 is an impurity and degradation product of exenatide. Alternative Names: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Glu-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2. Molecular formula: C184H281N49O61S. Mole weight: 4187.81.
Glu-AMS TEA is a competitive inhibitor of Escherichia coli glutamyl-tRNA synthetase (GluRS), with the Ki of 2.8 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1810728-44-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-159628A.
Glu-Asp-OH
Glu-Asp-OH is a dipeptide used as a diagnostic indicator of the disease. Alternative Names: L-α-Glutamyl-L-aspartic acid; Vesilute; (S)-2-((S)-2-Amino-4-carboxybutanamido)succinic acid. Grades: ≥ 98% (TLC). CAS No. 3918-84-1. Molecular formula: C9H14N2O7. Mole weight: 262.22.
Glubionate Calcium
Glubionate Calcium is a mineral supplement. It can be used to prevent or treat low blood calcium levels. Alternative Names: Calcium glubionate; Neocalglucon; Calcium, (4-O-β-D-galactopyranosyl-D-gluconato)(D-gluconato)-, monohydrate; D-Gluconic acid, 4-O-β-D-galactopyranosyl-, calcium complex; D-Gluconic acid, calcium complex; Calcium glucono-galacto-gluconate; Calcium gluconolactobionate; Gluconogalactogluconic acid, calcium salt; Hi-Glucon; Neo-Calglucon. CAS No. 12569-38-9. Molecular formula: C18H32CaO19.H2O. Mole weight: 610.53.
Glucagon (1-29), bovine, human
Glucagon (1-29), bovine, human, porcine is a peptide hormone, produced by pancreatic α-cells. Glucagon stimulates gluconeogenesis[1]. Glucagon (1-29), bovine, human, porcine activates HNF4α and increases HNF4α phosphorylation[2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glucagon. CAS No. 16941-32-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0082.
Glucagon (1-29), bovine, human hydrochloride
Glucagon (1-29), bovine, human, porcine hydrochloride is a peptide hormone, produced by pancreatic α-cells. Glucagon hydrochloride stimulates gluconeogenesis[1]. Glucagon (1-29), bovine, human, porcine hydrochloride activates HNF4α and increases HNF4α phosphorylation[2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glucagon hydrochloride. CAS No. 28270-04-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0082A.
Glucagon (19-29) (human, rat, porcine)
Glucagon is an endogenous short peptide. Alternative Names: Miniglucagon (human, rat, porcine). Grades: >95%. CAS No. 64790-15-4. Molecular formula: C61H89N15O18S. Mole weight: 1352.5.
Glucagon (22-29)
Glucagon (22-29) is partial agonist of Glucagon (19-29). Glucagon specifically inhibits the Ca2+ pump in liver plasma membranes independently of adenylate cyclase activation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 32204-93-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3617.
Glucagon arbitrary peak I
Glucagon arbitrary peak I is a derivative of Glucagon, a peptide hormone produced by alpha cells of the pancreas that regulates the blood glucose levels in human body.
Glucagon arbitrary peak II
Glucagon arbitrary peak II is a derivative of Glucagon, a peptide hormone produced by alpha cells of the pancreas that regulates the blood glucose levels in human body.
Glucagon arbitrary peak III
Glucagon arbitrary peak III is a derivative of Glucagon, a peptide hormone produced by alpha cells of the pancreas that regulates the blood glucose levels in human body.
Glucagon arbitrary peak IV
Glucagon arbitrary peak IV is a derivative of Glucagon, a peptide hormone produced by alpha cells of the pancreas that regulates the blood glucose levels in human body. Alternative Names: H-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Glu-Trp-Leu-Met-Asn-Thr-OH; (2S,5S,8S,11S,14S,17S,20S,23S,26S)-14-((1H-indol-3-yl)methyl)-5-(2-amino-2-oxoethyl)-26-((6S,9S,12S,15S)-1-amino-6-((S)-2-amino-3-hydroxypropanamido)-15-(3-amino-3-oxopropyl)-9-(3-guanidinopropyl)-1-imino-12-methyl-7,10,13-trioxo-2,8,11,14-tetraazahexadecanamido)-23-benzyl-17-(2-carboxyethyl)-2-((R)-1-hydroxyethyl)-11-isobutyl-20-isopropyl-8-(2-(methylthio)ethyl)-4,7,10,13,16,19,22,25-octaoxo-3,6,9,12,15,18,21,24-octaazaoctacosane-1,28-dioic acid. Molecular formula: C76H117N23O23S. Mole weight: 1752.95.
Glucagon arbitrary Peak IX
Glucagon arbitrary Peak IX is a derivative of Glucagon, a peptide hormone produced by alpha cells of the pancreas that regulates the blood glucose levels in human body. Alternative Names: H-His-Ser-Glu-Gly-Thr-Phe-Thr-Ser-Asp-OH. Molecular formula: C40H57N11O18. Mole weight: 979.94.
Glucagon arbitrary peak V
Glucagon arbitrary peak V is a derivative of Glucagon, a peptide hormone produced by alpha cells of the pancreas that regulates the blood glucose levels in human body. Alternative Names: H-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH. Molecular formula: C113H169N31O33S. Mole weight: 2521.80.
Glucagon arbitrary peak VI
Glucagon arbitrary peak VI is a derivative of Glucagon, a peptide hormone produced by alpha cells of the pancreas that regulates the blood glucose levels in human body.
Glucagon arbitrary peak VII
Glucagon arbitrary peak VII is a derivative of Glucagon, a peptide hormone produced by alpha cells of the pancreas that regulates the blood glucose levels in human body. Alternative Names: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Glu-Trp-Leu-Met-Asn-Thr-OH. Molecular formula: C153H224N42O50S. Mole weight: 3483.73.
Glucagon arbitrary peak VIII
Glucagon arbitrary peak VIII is a derivative of Glucagon, a peptide hormone produced by alpha cells of the pancreas that regulates the blood glucose levels in human body. Alternative Names: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-OH; (S)-2-((2S,5S,8S,11S,17S,20S,23S)-23-amino-17-(3-amino-3-oxopropyl)-8-benzyl-5,11-bis((R)-1-hydroxyethyl)-2,20-bis(hydroxymethyl)-24-(1H-imidazol-5-yl)-4,7,10,13,16,19,22-heptaoxo-3,6,9,12,15,18,21-heptaazatetracosanamido)succinic acid. Molecular formula: C40H58N12O17. Mole weight: 978.96.
Glucagon arbitrary Peak X
Glucagon arbitrary Peak X is a derivative of Glucagon, a peptide hormone produced by alpha cells of the pancreas that regulates the blood glucose levels in human body. Alternative Names: H-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-OH. Molecular formula: C64H100N20O22. Mole weight: 1501.60.
Glucagon arbitrary Peak XI
Glucagon arbitrary Peak XI is a derivative of Glucagon, a peptide hormone produced by alpha cells of the pancreas that regulates the blood glucose levels in human body. Alternative Names: H-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Glu-Asp-OH. Molecular formula: C64H99N19O23. Mole weight: 1502.58.
Glucagon arbitrary Peak XII
Glucagon arbitrary Peak XII is a derivative of Glucagon, a peptide hormone produced by alpha cells of the pancreas that regulates the blood glucose levels in human body. Alternative Names: H-Tyr-Ser-Lys-Tyr-Leu-Asp-OH; L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-aspartic acid. Molecular formula: C37H53N7O12. Mole weight: 787.86.
Glucagon arbitrary Peak XIII
Glucagon arbitrary Peak XIII is a derivative of Glucagon, a peptide hormone produced by alpha cells of the pancreas that regulates the blood glucose levels in human body. Alternative Names: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-OH. Molecular formula: C104H156N32O38. Mole weight: 2462.54.
Glucagon arbitrary Peak XIV
Glucagon arbitrary Peak XIV is a derivative of Glucagon, a peptide hormone produced by alpha cells of the pancreas that regulates the blood glucose levels in human body. Alternative Names: H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-OH; L-histidyl-L-seryl-L-glutaminyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-aspartic acid. Molecular formula: C77H109N19O28. Mole weight: 1748.80.
Glucagon di-lactose adduct-2
Lactose is used as a stabilizer for freeze-dried formulations of glucagon and upon storage Glucagon will react with lactose via Maillard reaction and lead to formation of impurities. Molecular formula: C177H265N43O69S. Mole weight: 4131.40.
Glucagon hydrochloride
Glucagon is a peptide hormone produced from proglucagon in pancreatic α cells that has a role in the regulation of glucose metabolism. Category: Active pharmaceutical ingredients. CAS No. 19179-82-9. Product ID: API19179829. Molecular formula: C153H225N43O49S; XHCl. Mole weight: 3482.8.
Glucagon Hydrochloride
Glucagon Hydrochloride. CAS No. 16941-32-5. Purity: Min. 98.0%. Product ID: ALC-FP-16941325. Molecular formula: C153H225N43O49S. Mole weight: 3482.75. Alfa Chemistry - ISO 9001:32057 Certified.
Glucagon Lactose adduct-1
Lactose is used as a stabilizer for freeze-dried formulations of glucagon and upon storage Glucagon will react with lactose via Maillard reaction and lead to formation of impurities. Molecular formula: C165H245N43O59S. Mole weight: 3807.08.
Glucagon lactose adduct-3
Lactose is used as a stabilizer for freeze-dried formulations of glucagon and upon storage Glucagon will react with lactose via Maillard reaction and lead to formation of impurities. Molecular formula: C165H245N43O59S. Mole weight: 3807.08.
Glucagon-like peptide 1 (1-37), human
Glucagon-like peptide 1 (1-37) is a pancreatic hormone synthesized by post-translational processing of proglucagon. It decreases plasma glucose level in high-fat-fed mice when administered at 25 nmol/kg. Glucagon-like peptide 1 (1-37) exhibits no effect on food intake in rats and does not enhance pancreatic insulin secretion. However it induces insulin expression in intestinal epithelial cells, which can restore glucose homeostasis when implanted into diabetic mice. Alternative Names: HuGLP-1; GLP-1 (1-37) (human, bovine, guinea pig, mouse, rat); Preproglucagon (92-128) (human, bovine, guinea pig, mouse, rat); H-His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH; L-histidyl-L-alpha-aspartyl-L-alpha-glutamyl-L-phenylalanyl-L-alpha-glutamyl-L-arginyl-L-histidyl-L-alanyl-L-alpha-glutamyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamyl-glycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysyl-glycyl-L-arginyl-glycine. Grades: ≥95%. CAS No. 87805-34-3. Molecular formula: C186H275N51O59. Mole weight: 4169.48.
Glucagon-like peptide 1 (1-37), human
Glucagon-like peptide 1 (1-37), human is a highly potent agonist of the GLP-1 receptor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GLP-1 (1-37) human. CAS No. 87805-34-3. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P1145.
Glucagon-Like Peptide 1 Receptor Agonist
A nonpeptidic quinoxaline compound that acts as a GLP-1R agonist and an allosteric modulator of GLP-1 binding. Shown to induce GLP-1R-mediated cAMP production in BHK plasma membrane preparations (EC50=101nM) and potentiate glucose-dependent insulin release in pancreatic islets derived from wild-type, but not GLP-1R -/-, mice. Unlike GLP-1, its biological activity is not inhibited by orthosteric antagonists such as Exendin. Group: Biochemicals. Alternative Names: 6,7-dichloro-N-(1,1-dimethylethyl)-3-(methylsulfonyl)-, 6,7-dichloro-2-methylsulfonyl-3-N-tert-butylaminoquinoxaline (DMB); Compound 2; GLP-1R Agonist. Grades: Highly Purified. CAS No. 281209-71-0. Pack Sizes: 5mg. Molecular Formula: C??H??Cl?N?O?S, Molecular Weight: 348.3. US Biological Life Sciences.
Worldwide
Glucagon-Like Peptide 1 Receptor Agonist - CAS 281209-71-0
Glucagon-Like Peptide 1 Receptor Agonist - CAS 281209-71-0. Uses: For analytical and research use. CAS No. 281209-71-0. Mole weight: 348.25. Catalog: AP281209710.
Glucagon-Like Peptide 1 Receptor Agonist II (4- (3- (benzyloxy) phenyl) -2- (ethylsulfinyl) -6- (trifluoromethyl) pyrimidine, Glucagon-Like Peptide 1 Receptor Agonist II, Compound B)
A pyrimidine small molecule that acts as a GLP-1 allosteric agonist that induces cAMP signaling in HEK293 cells expressing the GLP-1 receptor with EC50 = 0.66uM and 99% efficacy (similar data with rat GLP-1 receptor), does not compete with radiolabelled GLP-1 in receptor binding assays, and is not active in cells expressing the GLP-2, GIP, PTH, or glucagon receptors. In rodent islets, insulin secretion increases in a dose-dependent and glucose-dependent manner, either alone or in an additive fashion when combined with the endogenous GLP-1 peptide. In vivo, this molecule exhibits insulinotropic effects when dosed at 10mg/kg in SD rats undergoing an IVGTT and a hyperglycemic clamp. It is also shown to increase insulin secretion in perifusion assays involving normal and diabetic human islets ex vivo, at concentrations between 1 and 10uM. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Glucagon-Like Peptide (GLP) II, human
Glucagon-Like Peptide (GLP) II, human, a 33-amino acid Peptide derived from proglucagon C-terminal, is mainly produced by intestinal L cells. GLP II stimulates intestinal mucosal growth and reduces intestinal epithelial cell apoptosis. Alternative Names: Glucagon-like peptide 2; H-His-Ala-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Asp-OH; L-histidyl-L-alanyl-L-alpha-aspartyl-glycyl-L-seryl-L-phenylalanyl-L-seryl-L-alpha-aspartyl-L-alpha-glutamyl-L-methionyl-L-asparagyl-L-threonyl-L-isoleucyl-L-leucyl-L-alpha-aspartyl-L-asparagyl-L-leucyl-L-alanyl-L-alanyl-L-arginyl-L-alpha-aspartyl-L-phenylalanyl-L-isoleucyl-L-asparagyl-L-tryptophyl-L-leucyl-L-isoleucyl-L-glutaminyl-L-threonyl-L-lysyl-L-isoleucyl-L-threonyl-L-aspartic acid; [Ala19]Glucagon-Like Peptide II, rat; GLP-2 (1-33) (human); Glucagon-Like Peptide-2 (1-33). Grades: 95%. CAS No. 89750-15-2. Molecular formula: C165H254N44O55S. Mole weight: 3766.11.
Glucagon (swine)
Glucagon, a peptide compound, is effective in increasing the glucose concentration in bloodstream and could be released by pancreatic α cells. Alternative Names: Glucagonum; Glucagone; HG-Factor; His-ser-glu(nh2)-gly-thr-phe-thr-ser-asp-tyr-ser-lys-tyr-leu-asp-ser-arg-arg-ala-glu(NH2)-asp-phe-val-glu(NH2)-trp-leu-met-asp(NH2)-thr; Glucagon-like-immunoreactivity; Glucaton. Grades: 98%. CAS No. 16941-32-5. Molecular formula: C153H225N43O49S. Mole weight: 3482.75.
Glucamine
Glucamine. Alternative Names: (2R,3R,4R,5S)-6-Aminohexane-1,2,3,4,5-pentaol. CAS No. 488-43-7. Purity: 0.98. Product ID: CI-FC-0064. Molecular formula: C6H15NO5. Mole weight: 181.19 g/mol. IUPAC Name: (2R,3R,4R,5S)-6-aminohexane-1,2,3,4,5-pentol. Alfa Chemistry - ISO 9001:32057 Certified.
glucan 1,3-α-glucosidase
Does not act on nigeran. Group: Enzymes. Synonyms: exo-1,3-α-glucanase; glucosidase II; 1,3-α-D-glucan 3-glucohydrolase. Enzyme Commission Number: EC 3.2.1.84. CAS No. 9073-99-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3948; glucan 1,3-α-glucosidase; EC 3.2.1.84; 9073-99-8; exo-1,3-α-glucanase; glucosidase II; 1,3-α-D-glucan 3-glucohydrolase. Cat No: EXWM-3948.
glucan 1,3-α-glucosidase
Does not act on nigeran.
glucan 1,3-β-glucosidase
Acts on oligosaccharides, but very slowly on laminaribiose. Group: Enzymes. Synonyms: exo-1,3-β-glucosidase; β-1,3-glucan exo-hydrolase; exo (1?3)-glucanohydrolase; 1,3-β-glucan glucohydrolase. Enzyme Commission Number: EC 3.2.1.58. CAS No. 9073-49-8. exo-1,3-β-D-Glucanase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3921; glucan 1,3-β-glucosidase; EC 3.2.1.58; 9073-49-8; exo-1,3-β-glucosidase; β-1,3-glucan exo-hydrolase; exo (1?3)-glucanohydrolase; 1,3-β-glucan glucohydrolase. Cat No: EXWM-3921.
glucan 1,3-β-glucosidase
Acts on oligosaccharides, but very slowly on laminaribiose.
glucan 1,4-α-glucosidase
Most forms of the enzyme can rapidly hydrolyse 1,6-α-D-glucosidic bonds when the next bond in the sequence is 1,4, and some preparations of this enzyme hydrolyse 1,6- and 1,3-α-D-glucosidic bonds in other polysaccharides. This entry covers all such enzymes acting on polysaccharides more rapidly than on oligosaccharides. EC 3.2.1.20 α-glucosidase, from mammalian intestine, can catalyse similar reactions.
glucan 1,4-α-glucosidase
Most forms of the enzyme can rapidly hydrolyse 1,6-α-D-glucosidic bonds when the next bond in the sequence is 1,4, and some preparations of this enzyme hydrolyse 1,6- and 1,3-α-D-glucosidic bonds in other polysaccharides. This entry covers all such enzymes acting on polysaccharides more rapidly than on oligosaccharides. EC 3.2.1.20 α-glucosidase, from mammalian intestine, can catalyse similar reactions. Group: Enzymes. Synonyms: glucoamylase; amyloglucosidase; γ-amylase; lysosomal α-glucosidase; acid maltase; exo-1,4-α-glucosidase; glucose amylase; γ-1,4-glucan glucohydrolase; acid maltase; 1,4-α-D-glucan glucohydrolase. Enzyme Commission Number: EC 3.2.1.3. CAS No. 9032-08-0. Glucoamylase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3893; glucan 1,4-α-glucosidase; EC 3.2.1.3; 9032-08-0; glucoamylase; amyloglucosidase; γ-amylase; lysosomal α-glucosidase; acid maltase; exo-1,4-α-glucosidase; glucose amylase; γ-1,4-glucan glucohydrolase; acid maltase; 1,4-α-D-glucan glucohydrolase. Cat No: EXWM-3893.
glucan 1,4-α-maltohexaosidase
cf. EC 3.2.1.3 glucan 1,4-α-glucosidase, which removes successive glucose residues; EC 3.2.1.2 β-amylase, which removes successive maltose residues; EC 3.2.1.116 glucan 1,4-α-maltotriohydrolase, which removes successive maltotriose units and EC 3.2.1.60 glucan 1,4-α-maltotetraohydrolase, which removes successive maltotetraose residues. The products have the α-configuration. Group: Enzymes. Synonyms: exo-maltohexaohydrolase; 1,4-α-D-glucan maltohexaohydrolase. Enzyme Commission Number: EC 3.2.1.98. CAS No. 72561-12-7. Glucan 1,4-α-maltohexaosidase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3961; glucan 1,4-α-maltohexaosidase; EC 3.2.1.98; 72561-12-7; exo-maltohexaohydrolase; 1,4-α-D-glucan maltohexaohydrolase. Cat No: EXWM-3961.
glucan 1,4-α-maltohexaosidase
cf. EC 3.2.1.3 glucan 1,4-α-glucosidase, which removes successive glucose residues; EC 3.2.1.2 β-amylase, which removes successive maltose residues; EC 3.2.1.116 glucan 1,4-α-maltotriohydrolase, which removes successive maltotriose units and EC 3.2.1.60 glucan 1,4-α-maltotetraohydrolase, which removes successive maltotetraose residues. The products have the α-configuration.
Glucan 1,4-α-maltohexaosidase 13A from Bacillus halodurans, Recombinant
Glucan 1,4-alpha-maltohexaosidase (EC 3.2.1.98, exo-maltohexaohydrolase, 1,4-alpha-D-glucan maltohexaohydrolase) is an enzyme with systematic name 4-alpha-D-glucan maltohexaohydrolase. This enzyme catalyses the following chemical reaction: Hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltohexaose residues from the non-reducing chain ends. The products have the alpha-configuration. Group: Enzymes. Synonyms: Glucan 1,4-alpha-maltohexaosidase; EC 3.2.1.98; exo-maltohexaohydrolase; 1,4-alpha-D-glucan maltohexaohydrolase; 4-α-D-glucan maltohexaohydrolase4-α-D-glucan maltohexaohydrolase. Enzyme Commission Number: EC 3.2.1.98. CAS No. 72561-12-7. Purity: >90% by SDS-PAGE. Glucan 1,4-α-maltohexaosidase. Mole weight: 64.9 kDa. Storage: This enzyme is shipped at room temperature but should be stored at -20 °C. Form: 35 mM NaHepes buffer, pH 7.5, 750 mM NaCl, 200 mM imidazol, 3.5 mM CaCl2, 0.02% sodium azide and 25% (v/v) glycerol. Source: E. coli. Species: Bacillus halodurans. Glucan 1,4-alpha-maltohexaosidase; EC 3.2.1.98; exo-maltohexaohydrolase; 1,4-alpha-D-glucan maltohexaohydrolase; 4-α-D-glucan maltohexaohydrolase4-α-D-glucan maltohexaohydrolase. Cat No: NATE-1296.