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| Product | Description | |
|---|---|---|
| Globotriaosylceramid?e Sphingosine-d2,13C tert-Butyldimethylsilyl | Globotriaosylceramid?e Sphingosine-d2,13C tert-Butyldimethylsilyl is a labeled Fabry disease biomarker. Synonyms: (2S,?3R,?4E)?-2-Amino-3-((tert-butyldimethylsilyl)oxy)-4-octadecenyl-d2,13C O-α-D-Galactopyranosyl-(1→4)?-O-β-D-galactopyranosyl-(1→4)?-β-D-glucopyranoside; lyso-Gb3-d2,13C tert-Butyldimethylsilyl; (2R,3R,4S,5R,6R)-2-(((2R,3R,4R,5R,6S)-6-(((2R,3S,4R,5R,6R)-6-(((2S,3R,E)-2-Amino-3-((tert-butyldimethylsilyl)oxy)octadec-4-en-1-yl-d2, 13C)oxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. Molecular formula: C41[13C]H79D2NO17Si. Mole weight: 903.18. |  |
| Globotriaosylsphingosine | Globotriaosylsphingosine, or Gb3, is a crucial biomarker used in the biomedical industry to diagnose and monitor the progression of Fabry disease. This rare genetic disorder results from the deficiency of a specific enzyme, leading to the abnormal accumulation of Gb3 within various organs. Precise and sensitive detection of Gb3 helps physicians determine the severity of Fabry disease and devise personalized treatment plans accordingly. Synonyms: a-D-Gal-(1→4)-b-D-Gal-(1→4)-b-D-Glc-1→O-sphingosine; Lysoglobotriaosylceramide; Ceramide trihexoside; lysoGb3; (2S,3R,4E)-2-Amino-3-hydroxy-4-octadecen-1-yl O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside; β-D-Glucopyranoside, (2S,3R,4E)-2-amino-3-hydroxy-4-octadecenyl O-α-D-galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-; Globotriaosylceramide sphingosine; lyso-Gb3. Grade: >99%. CAS No. 126550-86-5. Molecular formula: C36H67NO17. Mole weight: 785.91. | |
| Globotriaosylsphingosine | Globotriaosylsphingosine (Lyso-Gb3) inhibits the growth of fibroblasts, as well as their differentiation into myofibroblasts, and collagen expression. Globotriaosylsphingosine can be used for Fabry disease research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Lyso-Gb3; Lyso-GL3. CAS No. 126550-86-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-N12408. |  |
| Globotriose | Globotriose is a carbohydrate product used in biomedicine to study the role of glycolipids in various diseases and drug development. It is commonly utilized as a mimic to study the biological interactions with globotriaosylceramide (Gb3), which is involved in the progression of certain infections, such as E. coli and Shiga toxin-producing bacteria. Globotriose provides valuable insights into the development of therapeutics targeting Gb3-mediated diseases. Synonyms: 4-O-(4-O-α-D-Galactopyranosyl-β-D-galactopyranosyl)-D-glucose; Gal-a-1,4-Gal-b-1,4-Glc; pk-Antigen; Globotriaose; O-α-D-Galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-D-glucose; alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-D-Glc; alpha-D-Galp-(1->4)-beta-D-Galp-(1->4)-D-Glcp. Grade: ≥95%. CAS No. 66580-68-5. Molecular formula: C18H32O16. Mole weight: 504.44. | |
| Globotriose 2-(2-carboxyethylthio)ethane | Globotriose 2-(2-carboxyethylthio)ethane is an extensively employed compound, serving as a cornerstone for research purposes in various ailments including hemolytic uremic syndrome and Escherichia coli-induced bacterial infections. Synonyms: 2-(2-Carboxyethylthio)-ethyl 4-O-[4-O(a-D-galactopyranosyl)-b-D-galactopyranosyl]-b-D-glucopyranoside. Molecular formula: C23H40O18S. Mole weight: 636.62. | |
| Globotriose-APE-HSA | Globotriose-APE-HSA. | |
| Globotriose-GEL | Globotriose-GEL. | |
| Globotriose-HSA | Globotriose-HSA. | |
| Globotriose-HSA (3 atom spacer) | Globotriose-HSA (3 atom spacer) is a potential therapeutic agent used in the treatment of shiga toxin-producing E. coli infections. It comprises a synthetic molecule made of three sugar molecules connected to human serum albumin with a three-atom spacer. The compound can bind to the shiga toxin produced by E. coli, preventing it from attaching to cell receptors and causing damage to vital organs. Synonyms: Globotriose-HSA conjugate, 3 Atom spacer; Gal(a1-4)Gal(b1-4)Glc-HSA (3 atom spacer); alpha-D-Gal-(1->4)-beta-D-Gal-(1->4)-D-Glc-HSA (3 atom spacer); O-α-D-Galactopyranosyl-(1→4)-O-β-D-galactopyranosyl-(1→4)-D-glucose-HSA (3 atom spacer). | |
| Globotriose-sp-biotin | Globotriose-sp-biotin is a crucial component utilized for studying and detecting diseases caused by certain strains of Escherichia coli bacteria. As a specific ligand, it enhances the identification and quantification of bacterial binding to cell surfaces, aiding in the research of infections caused by these pathogens. Synonyms: Gala1-4Galb1-4Glcb-OCH2CH2NH-biotin. | |
| Globularin | Globularin is a natural iridoid isolated from the herb of Globularia alypum. Synonyms: [(1aS)-1a,1bα,2,5aα,6,6aβ-Hexahydro-6α-hydroxy-1aβ-[[[(E)-1-oxo-3-phenyl-2-propenyl]oxy]methyl]oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]β-D-glucopyranoside. Grade: >95%. CAS No. 1399-49-1. Molecular formula: C24H28O11. Mole weight: 492.47. | |
| Globulins Cohn fraction II, III from goat | Globulins Cohn fraction II, III from goat. Uses: For analytical and research use. CAS No. 68476-36-8. EC Number: 270-678-2. Catalog: AP68476368-B. |  |
| Globulins Cohn fraction II, III human | Globulins Cohn fraction II, III human. Uses: For analytical and research use. CAS No. 68476-36-8. EC Number: 270-678-2. Catalog: AP68476368-C. | |
| Globulins Cohn fraction IV-4 human | Globulins Cohn fraction IV-4 human. Uses: For analytical and research use. CAS No. 68476-36-8. EC Number: 270-678-2. Catalog: AP68476368-D. | |
| Globulol | Globulol is a terpenoid metabolite and Antimicrobial agent. Globulol can be isolated from Alpinia oxyphylla Miq. Globulol binds to PAK4, reduces the expression level of PAK4 in cancer cells, decreases the phosphorylation of AKT, and downregulates the expressions of STAT3, phosphorylated STAT3, and PD-L1. Globulol promotes the secretion of CCL4 by cancer cells. Globulol reduces the viability and proliferation ability of cancer cells, induces G0/G1 cell cycle arrest and Apoptosis in cancer cells, and inhibits cancer cell migration and the integrity of 3D tumor spheres. Globulol enhances the relevant effects of anti-PD-1 agents in the cancer cell microenvironment. Globulol exhibits anticancer activity against liver cancer. Globulol inhibits the mycelial growth of phytopathogenic fungi and the growth of phytopathogenic bacteria. Globulol can be used in studies related to hepatocellular carcinoma[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 489-41-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N8389. | |
| Glofitamab | Glofitamab (RO7082859) is a T-cell-engaging bispecific antibody possessing a novel 2:1 structure with bivalency for CD20 on B cells and monovalency for CD3 on T cells. Glofitamab leads to T-cell activation, proliferation, and tumor cell killing upon binding to CD20 on malignant cells. Glofitamab induces durable complete remissions in relapsed or refractory B-Cell non-Hodgkin lymphoma (B-NHL)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RO7082859; RG-6026. CAS No. 2229047-91-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99024. | |
| Glofitamab | Glofitamab is a T-cell-engaging bispecific antibody possessing a novel 2:1 structure with bivalency for CD20 on B cells and monovalency for CD3 on T cells. Glofitamab is used as an effective therapy for relapsed or refractory diffuse large B-cell lymphoma. Synonyms: RO7082859; RG6026. CAS No. 2229047-91-8. | |
| Glomecidin | It is produced by the strain of Streptomyces lavendulae H698 SY2. It has antibacterial activity on several plant pathogenic fungi, including Glomerella cingulata, Colletotrichum gloeosporioides and C. lagenarium with MIC (μg/mL) of 0.78, 0.78 and 1.56, respectively. It has no effect on other fungi, yeast and bacteria. Molecular formula: C27H37N7O7. Mole weight: 571.62. | |
| Glomellic acid | Glomellic acid. Synonyms: Benzoic acid, 2-hydroxy-4-[[2-hydroxy-4-methoxy-6-(2-oxopentyl)benzoyl]oxy]-6-(2-oxopentyl)-; Glomellsaeure. CAS No. 52589-14-7. Molecular formula: C25H28O9. Mole weight: 472.48. | |
| Glomelliferonic acid | Glomelliferonic acid is a depside from the Lichen Neofuscelia subincerta. Synonyms: ACMC-20miur; 11H-Dibenzo[b,e][1,4]dioxepin-7-carboxylic acid, 8-hydroxy-3-methoxy-11-oxo-1-(2-oxopentyl)-6-pentyl-; 8-Hydroxy-3-methoxy-11-oxo-1-(2-oxopentyl)-6-pentyl-11H-dibenzo[b,e][1,4]dioxepine-7-carboxylic acid. CAS No. 113706-23-3. Molecular formula: C25H28O8. Mole weight: 456.48. | |
| Glomeratose A | Botanical Source: Group: Biochemicals. Grades: Plant Grade. CAS No. 202471-84-9. Pack Sizes: 10mg, 20mg. US Biological Life Sciences. |  Worldwide |
| Glomerular Microvascular Endothelial Cells, Human (Frozen) | Passage 2 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: 1ml. US Biological Life Sciences. | Worldwide |
| Glomerular Microvascular Endothelial Cells, Human (T-25 flask) | Passage 2 cells are shipped in proliferating culture with a confluence of >90%. ENDO-Growth medium containing 5% serum and growth supplement is recommended for culture. Cells have an average population doubling level of >16 when cultured. Group: Biologicals. Grades: Cell Culture Grade. Pack Sizes: T-25 flask. US Biological Life Sciences. | Worldwide |
| Glomosporin | It is produced by the strain of Glomospora sp. BAUA 2825. It is a cyclic ester peptide antifungal antibiotic, and it has moderate anti-aspergillus flavus (including aspergillus Niger and Aspergillus Niger), yeast activity (MIC is 16 μg/mL). Synonyms: [(3R,18R)-9,12-bis(2-amino-2-oxoethyl)-3-[(1R)-1-hydroxyethyl]-6,21-bis(hydroxymethyl)-25-(2-hydroxytetradecan-2-yl)-18-methyl-2,5,8,11,14,17,20,23-octaoxo-1-oxa-4,7,10,13,16,19,22-heptaazacyclopentacosan-15-yl]acetic acid. CAS No. 288631-37-8. Molecular formula: C42H71N9O17. Mole weight: 974.06. | |
| GloPIPs Biotin-PI(3,4,5)P3 | GloPIPs Biotin-PI(3,4,5)P3 is labelled at the sn-1 position with BODIPY®-FL (505/513), BODIPY®-TMR (544/574), or biotin. The sn-1 linkage in these labelled PIPs has been changed to a more stable amide from an ester. Phosphatidylinositol 3,4,5-trisphosphate, formed from PI(4,5)P2 through phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. Grade: >95%. Molecular formula: C31H51N4Na7O23P4S. Mole weight: 1164.64. | |
| GloPIPs Biotin-PI(3,4)P2 | GloPIPs Biotin-PI(3,4)P2 is labelled at the sn-1 position with BODIPY®-FL (505/513), BODIPY®-TMR (544/574), or biotin. The sn-1 linkage in these labelled PIPs has been changed to a more stable amide from an ester. PI(3,4)P2 is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP, TPTE, etc.). PI(3,4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions. Grade: >95%. Molecular formula: C31H52N4Na5O20P3S. Mole weight: 1040.69. | |
| GloPIPs Biotin-PI(3,5)P2 | GloPIPs Biotin-PI(3,5)P2 is labelled at the sn-1 position with BODIPY®-FL (505/513), BODIPY®-TMR (544/574), or biotin. The sn-1 linkage in these labelled PIPs has been changed to a more stable amide from an ester. PI(3,5)P2 is in very low abundance and is required for retrograde membrane trafficking from lysosomal and late endosomal compartments to the Golgi and is involved in autophagy. PI(3,5)P2 levels are controlled by the 5-kinase PIKfyve and the 5-phosphatase Fig4/Sac3 and disregulation is linked to several human neuropathies (eg Chacot-Marie-Tooth disease). Grade: >95%. Molecular formula: C31H52N4Na5O20P3S. Mole weight: 1040.69. | |
| GloPIPs Biotin-PI(3)P | GloPIPs Biotin-PI(3)P is labelled at the sn-1 position with BODIPY®-FL (505/513), BODIPY®-TMR (544/574), or biotin. The sn-1 linkage in these labelled PIPs has been changed to a more stable amide from an ester. PI(3)P is enriched in early endosomes having roles in endosome fusion and receptor sorting and internalization in multivesicular bodies. PI(3)P has also been found at the plasma membrane and is involved in the translocation of the glucose transport protein GLUT4. Grade: >95%. Molecular formula: C31H53N4Na3O17P2S. Mole weight: 916.75. | |
| GloPIPs Biotin-PI(4,5)P2 | GloPIPs Biotin-PI(4,5)P2 is labelled at the sn-1 position with BODIPY®-FL (505/513), BODIPY®-TMR (544/574), or biotin. The sn-1 linkage in these labelled PIPs has been changed to a more stable amide from an ester. PI(4,5)P2 has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PI(3,4,5)P3. Molecular formula: C35H53BF2N4O19P3. Mole weight: 975.55. | |
| GloPIPs Biotin-PI(4)P | PI(4)P is the biosynthetic precursor to PI(4,5)P2 and has an important role in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex. Molecular formula: C31H53N4Na3O17P2S. Mole weight: 916.75. | |
| GloPIPs Biotin-PI(5)P | PI(5)P is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4,5)P2 by Type II PIP kinases. Molecular formula: C31H53N4Na3O17P2S. Mole weight: 916.75. | |
| GlowDot | GlowDot. |  |
| GLP-1 | Glucagon-like peptide-1 (GLP-1) is a potent insulin secretagogue that has multiple synergetic effects on the glucose-dependent insulin secretion pathways of the beta-cell. Synonyms: Glucagon-like peptide 1. CAS No. 89750-14-1. Molecular formula: C149H226N40O45. Mole weight: 3297.7. | |
| GLP-1 (1-36) amide (human, bovine, guinea pig, mouse, rat) | GLP-1 (1-36) amide is a promising peptide hormone unlocking avenues for type 2 diabetes mellitus research. Its extraordinary resemblance to the native GLP-1 facilitates heightened glucose-dependent insulin secretion. Synonyms: Preproglucagon (92-127) amide (human, bovine, guinea pig, mouse, rat); Glucagon-like peptide 1 (1-36) amide (human, bovine, guinea pig, mouse, rat); H-His-Asp-Glu-Phe-Glu-Arg-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2; L-histidyl-L-alpha-aspartyl-L-alpha-glutamyl-L-phenylalanyl-L-alpha-glutamyl-L-arginyl-L-histidyl-L-alanyl-L-alpha-glutamyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamyl-glycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysyl-glycyl-L-argininamide. Grade: ≥95%. CAS No. 99658-04-5. Molecular formula: C184H273N51O57. Mole weight: 4111.44. | |
| GLP-1 (1-36) amide (human, rat) | GLP-1 (1-36) amide (human, rat) (Glucagon-like Peptide 1 (1-36) amide (human, rat)) is a molecular variant of glucagon-like peptide 1 (GLP-1)-(7-36) amide. GLP-1 (1-36) amide (human, rat) can stimulate [14C]aminopyrine accumulation on enzymatically dispersed enriched rat parietal cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glucagon-like Peptide 1 (1-36) amide (human, rat). CAS No. 99658-04-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P5815. | |
| GLP-1 (25-37), human | GLP-1 is a potent insulin secretagogue that has multiple synergetic effects on the glucose-dependent insulin secretion pathways of the beta-cell. Synonyms: Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly. Molecular formula: C70H111N19O16. Mole weight: 1474.84. | |
| GLP-1(28-36)amide | GLP-1(28-36)amide, a C-terminal nonapeptide of GLP-1, is a major product derived from the cleavage of GLP-1 by the neutral endopeptidase (NEP). GLP-1(28-36)amide is an antioxidant and targets to mitochondrion, inhibits mitochondrial permeability transition (MPT). GLP-1(28-36)amide has anti-diabetic and cardioprotection effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1225021-13-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3101. | |
| GLP-1(28-36)amide acetate | GLP-1(28-36)amide acetate inhibits mitochondrial permeability transition with antioxidant, anti-diabetic and cardioprotection activities. Molecular formula: C56H89N15O11. Mole weight: 1148.40. | |
| GLP-1 (7-36) Acetate | GLP-1 (7-36) is an intestinal hormone that stimulates glucose-induced β cells to secrete insulin. Synonyms: Human GLP-1-(7-36)-amide Acetate. Grade: >98%. CAS No. 1119517-19-9. Molecular formula: C149H226N40O45.xC2H4O2. Mole weight: 3394.67. | |
| GLP-1(7-36) amide | GLP-1(7-36) amide is a glucose-dependent insulinotropic peptide displaying high affinity for GLP-1 receptors expressed in rat insulinoma-derived RINm5F cells (Kd = 204 pM). GLP-1 (7-36) amide exhibits antiapoptotic effects in hippocampal neurons and reduces food intake in fasted rats following central administration. Synonyms: GLP-1; GLP-1 (7-36) amide; Insulinotropin. Grade: 98%. CAS No. 107444-51-9. Molecular formula: C149H226N40O45. Mole weight: 3297.67. | |
| GLP-1(7-36), amide | GLP-1(7-36), amide is a physiological incretin hormone that stimulates insulin secretion. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glucagon-like peptide-1 (GLP-1)(7-36), amide; Human GLP-1 (7-36), amide. CAS No. 107444-51-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0054A. | |
| GLP-1(7-36), amide acetate | GLP-1(7-36), amide acetate is a major intestinal hormone that stimulates glucose-induced insulin secretion from β cells. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Glucagon-like peptide-1 (GLP-1)(7-36), amide acetate; Human GLP-1 (7-36), amide acetate. CAS No. 1119517-19-9. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0054. | |
| GLP-1 (7-36), amide, biotin labeled | Glucagon-Like Peptide 1 (GLP-1) (7-36)-Lys (Biotin), amide, human is an C-terminal-labelled biotinylated GLP-1 (7-36) amide. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GLP-1 (7-36)-Lys(biotin)-amide. CAS No. 1802086-70-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P2535. | |
| GLP-1 (7-36) amide (chicken, common turkey) | GLP-1 (7-36) amide (chicken, common turkey). Synonyms: Preproglucagon (118-147) amide (chicken, common turkey); H-His-Ala-Glu-Gly-Thr-Tyr-Thr-Ser-Asp-Ile-Thr-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Asn-Gly-Arg-NH2; L-histidyl-L-alanyl-L-alpha-glutamyl-glycyl-L-threonyl-L-tyrosyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-isoleucyl-L-threonyl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamyl-glycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-asparagyl-glycyl-L-argininamide; Glucagon-Like Peptide 1 (7-36) amide (chicken, common turkey). Grade: ≥95% by HPLC. CAS No. 1802078-26-7. Molecular formula: C149H224N40O47. Mole weight: 3327.66. | |
| GLP-1 (7-36) amide trifluoroacetate salt | GLP-1 (7-36) amide is an important peptide hormone that displays a strong insulinotropic effect. It binds the GLP-1 receptor (pIC50 = 8.5) in the pancreas and shows various antidiabetic effects. Synonyms: Glucagon-like Peptide 1 (7-36) amide. Mole weight: 3297.6. | |
| GLP-1 (7-36)-Lys(6-FAM) amide (human, bovine, guinea pig, mouse, rat) | GLP-1 (7-36)-Lys(6-FAM) amide (human, bovine, guinea pig, mouse, rat). Synonyms: Preproglucagon (98-127)-Lys(6-FAM)amide (human, bovine, guinea pig, mouse, rat); H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Lys(fluorescein-6-carbonyl)-NH2; Proglucagon (78-107)-Lys(6-FAM)amide (human, bovine, guinea pig, mouse, rat); Glucagon-Like Peptide 1 (7-36)-Lys(6-FAM)amide (human, bovine, guinea pig, mouse, rat). Grade: ≥95%. CAS No. 1802089-53-7. Molecular formula: C176H248N42O52. Mole weight: 3784.16. | |
| GLP-1 (7-36)-Lys(biotinyl) amide (human, bovine, guinea pig, mouse, rat) | GLP-1 (7-36)-Lys(biotinyl) amide (human, bovine, guinea pig, mouse, rat). Synonyms: Preproglucagon (98-127)-Lys(biotinyl) amide (human, bovine, guinea pig, mouse, rat); H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Lys(biotinyl)-NH2; Proglucagon (78-107)-Lys(biotinyl)amide (human, bovine, guinea pig, mouse, rat); Glucagon-Like Peptide 1 (7-36)-Lys(biotinyl)amide (human, bovine, guinea pig, mouse, rat). Grade: ≥95%. CAS No. 1802086-70-9. Molecular formula: C165H252N44O48S. Mole weight: 3652.15. | |
| GLP-1(7-37) | GLP-1(7-37) is an intestinal insulinotropic hormone that augments glucose induced insulin secretion. Uses: Scientific research. Category: Signaling pathways. CAS No. 106612-94-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P0055. | |
| GLP-1(7-37) | GLP-1 (7-37) is an insulinotropic peptide generated from the precursor peptide GLP-1 (1-37). It is a potent stimulator of insulin secretion at concentrations as low as 5 X 10(-11) M and has no effect on insulin secretion even at concentrations as high as 5 X 10(-7) M. It participates in the physiological regulation of insulin secretion. Uses: Glp-1 (7-37) acetate participates in the physiological regulation of insulin secretion. Synonyms: Proglucagon (78-108) (human, bovine, guinea pig, mouse, rat); Insulinotropin (human, bovine, guinea pig, mouse, rat); Glucagon-Like Peptide 1 (7-37) (human, bovine, guinea pig, mouse, rat); Preproglucagon (98-128) (human, bovine, guinea pig, mouse, rat); GLP-1 (7-37) human; Glucagon-like Peptide-1 (7-37); H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH; L-histidyl-L-alanyl-L-alpha-glutamyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-seryl-L-seryl-L-tyrosyl-L-leucyl-L-alpha-glutamyl-glycyl-L-glutaminyl-L-alanyl-L-alanyl-L-lysyl-L-alpha-glutamyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-tryptophyl-L-leucyl-L-valyl-L-lysyl-glycyl-L-arginyl-glycine. Grade: 98%. CAS No. 106612-94-6. Molecular formula: C151H228N40O47. Mole weight: 3355.67. | |
| GLP-1(7-37) acetate | GLP-1(7-37) acetate is an intestinal insulinotropic hormone that augments glucose induced insulin secretion[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1450806-98-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0055A. | |
| GLP-1 (9-36) amide | GLP-1 (9-36) amide is an N-terminal truncated metabolite of glucagon-like peptide GLP-1-(7-36) formed by dipeptidyl peptidase-IV cleavage. GLP-1 (9-36) amide functions as a human GLP-1 receptor antagonist. Synonyms: Glucagon-like peptide-1 (9-36) amide; Glucagon-like peptide-1 (9 36) amide. CAS No. 161748-29-4. Molecular formula: C140H214N36O43. Mole weight: 3089.44. | |
| GLP-1(9-36)amide | GLP-1(9-36)amide is a major metabolite of glucagon-like peptide-1-(7-36) amide formed by the enzyme dipeptidyl peptidase-4 (DPP-4). GLP-1(9-36)amide acts as an antagonist to the human pancreatic GLP-1 receptor[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 161748-29-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1141. | |
| GLP-1 antagonist | A glucagon-like peptide-1 (GLP-1) receptor antagonist. Synonyms: GLP-1 antagonist; GLP 1 antagonist; N-[[4,5-dimethyl-1-[(2-methylphenyl)methyl]imidazol-2-yl]methyl]-2,4-dimethoxy-N-(3-methylbutyl)benzamide. Grade: 99%. CAS No. 475466-57-0. Molecular formula: C28H37N3O3. Mole weight: 463.61. | |
| GLP-1, IGF-1 (1-3) | GLP-1, IGF-1 (1-3) is a fragment of amino acids of Glucagon-like peptide-1. Grade: 98%. Molecular formula: C12H19N3O6. Mole weight: 301.3. | |
| GLP-1 moiety from Dulaglutide | GLP-1 moiety from Dulaglutide is a 31-amino acid fragment of Dulaglutide. GLP-1 moiety from Dulaglutide is a glucagon-like peptide 1 receptor (GLP-1) agonist. Dulaglitude can be used in researches of diabetes and myocardial injury[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: [Gly8,36,Glu22]-GLP-1 (7-37). CAS No. 1197810-60-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P1348. | |
| GLP-1 moiety from Dulaglutide | GLP-1 moiety from Dulaglutide is a fragment of Dulaglutide containing 31 amino acids, and Dulaglutide is a glucagonlike peptide 1 receptor (GLP-1) agonist. Synonyms: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Glu-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Gly-Gly. Grade: ≥98%. Molecular formula: C149H221N37O49. Mole weight: 3314.62. | |
| GLP-1R agonist 10 | GLP-1R agonist 10 (Compound 109a) is a GLP-1 agonist with an EC50 of 0.051 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2762515-25-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-147623. | |
| GLP-1R agonist 2 | GLP-1R agonist 2 (compound 2) is an effective GLP-1R agonist that exerts its activating effect by forming hydrogen bonds with the Tyr42, Cys71, and Ser84 residues of GLP-1R. GLP-1R agonist 2 has the potential for research in metabolic diseases such as type 2 diabetes and obesity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 281209-71-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121835. | |
| GLP-1R agonist DMB | GLP-1R agonist DMB is a glucagon-like peptide-1 (GLP-1) receptor agonist used potentially for the treatment of type 2 diabetes. Uses: Potential treatment of type 2 diabetes. Synonyms: N-(tert-Butyl)-6,7-dichloro-3-(methylsulfonyl)quinoxalin-2-amine. Grade: 99%. CAS No. 281209-71-0. Molecular formula: C13H15Cl2N3O2S. Mole weight: 348.25. | |
| GLP-1R Antagonist 1 | GLP-1R Antagonist 1 (compound 5d) is an orally active, CNS penetrant and non-competitive antagonist of glucagon-like peptide 1 receptor (GLP-1R), with an IC50 of 650 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 488097-06-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101116. | |
| GLP-1 receptor agonist 10 | GLP-1 receptor agonist 10 (compound 42) is an agonist of GLP Receptor. GLP-1 receptor agonist 10 inhibits food intake and reduces glucose excursion in mice. GLP-1 receptor agonist 10 can be used in the study of type 2 diabetes (T2DM) and obesity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3015555-46-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153798. | |
| GLP-1 receptor agonist 11 | GLP-1 receptor agonist 11 (compound 3) is an agonist of GLP Receptor. GLP-1 receptor agonist 11 can be used in the study of diseases such as diabetes and non-alc. fatty liver disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2784590-83-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153815. | |
| GLP-1 receptor agonist 2 | GLP-1 receptor agonist 2 is a glucagon-like peptide-1 receptor (GLP-1R) agonist[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2230197-64-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-112679. | |
| GLP-1 receptor agonist 2 | GLP-1 receptor agonist 2 is an agonist of glucagon-like peptide-1 receptor (GLP-1R). Synonyms: 1H-Benzimidazole-6-carboxylic acid, 2-[[(2S)-4-[6-[(4-chloro-2-fluorophenyl)methoxy]-2-pyridinyl]-2-methyl-1-piperazinyl]methyl]-1-[(2S)-2-oxetanylmethyl]-; 2-{[(2S)-4-{6-[(4-Chloro-2-fluorobenzyl)oxy]-2-pyridinyl}-2-methyl-1-piperazinyl]methyl}-1-[(2S)-2-oxetanylmethyl]-1H-benzimidazole-6-carboxylic acid. Grade: ≥95%. CAS No. 2230197-64-3. Molecular formula: C30H31ClFN5O4. Mole weight: 580.05. | |
| GLP-1 receptor agonist 3 | GLP-1 receptor agonist 3 is a GLP-1 receptor agonist with EC50s of 1.1 and 13 nM in Clone H6 and Clone C6 cell lines assay, respectively. (Extracted from patent WO2018109607A1, Example 4A-1). Synonyms: 1H-Benzimidazole-6-carboxylic acid, 2-[[4-[6-[(4-cyano-2-fluorophenyl)methoxy]-2-pyridinyl]-1-piperidinyl]methyl]-1-[(2R)-2-oxetanylmethyl]-; 2-[(4-{6-[(4-Cyano-2-fluorobenzyl)oxy]-2-pyridinyl}-1-piperidinyl)methyl]-1-[(2R)-2-oxetanylmethyl]-1H-benzimidazole-6-carboxylic acid. Grade: ≥95%. CAS No. 2230200-09-4. Molecular formula: C31H30FN5O4. Mole weight: 555.60. | |
| GLP-1 receptor agonist 4 | GLP-1 receptor agonist 4, a glucagon-like peptide-1 receptor (GLP-1R) agonist with an EC50 of 64.5 nM, can be used in the study of diabetes treatment. (Extracted from patent WO2009111700A2, compound 87). Synonyms: (S)-3-(4'-Cyano-[1,1'-biphenyl]-4-yl)-2-((3R,8S)-3-(4-((3,4-dichlorobenzyl)oxy)phenyl)-1-methyl-2-oxo-7-((S)-1-phenylpropyl)-2,3,6,7,8,9-hexahydro-1H-[1,4]oxazino[3,2-g]isoquinoline-8-carboxamido)propanoic acid; (2S)-3-(4'-Cyano-4-biphenylyl)-2-[({(3R,8S)-3-{4-[(3,4-dichlorobenzyl)oxy]phenyl}-1-methyl-2-oxo-7-[(1S)-1-phenylpropyl]-2,3,6,7,8,9-hexahydro-1H-[1,4]oxazino[3,2-g]isoquinolin-8-yl}carbonyl)amino]propanoic acid. Grade: ≥95%. CAS No. 1187061-62-6. Molecular formula: C51H44Cl2N4O6. Mole weight: 879.82. | |
| GLP-1 receptor agonist 7 | GLP-1 receptor agonist 7 is a potent glucagon-like peptide-1 (GLP-1) agonist with potential to study GLP-1-related diseases, disorders and conditions, including diabetes mellitus. (Extracted from patent WO2021219019A1, compound 130b). Synonyms: 2-((4-((S)-3-(4-chloro-2-fluorophenyl)-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperidin-1-yl)methyl)-3-(((S)-oxetan-2-yl)methyl)-3H-imidazo[4,5-b]pyridine-5-carboxylic acid. CAS No. 2736447-04-2. Molecular formula: C31H30ClFN4O5. Mole weight: 593.05. | |
| GLP-1 receptor agonist 7 | GLP-1 receptor agonist 7 (Compound 130b) is a potent agonist of glucagon-like peptide-1 (GLP-1). GLP-1 receptor agonist 7 generates cAMP under the mediation of GLP-1R with an EC50 of ≤ 0.2 nM. GLP-1 receptor agonist 7 can be used to study diseases related to the GLP-1 receptor (particularly type 2 diabetes)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2736447-04-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-145412. | |
| GLP-1 receptor agonist 8 | GLP-1 receptor agonist 8, a potent GLP-1 receptor agonist, has potential in the study of diabetes, obesity and non-alcoholic fatty liver disease (NAFLD). (Extracted from patent WO2019239319A1, compound 17). Synonyms: ammonium (R)-2-((4-(2-(4-chloro-2-fluorophenyl)-2-methylbenzo[d][1,3]dioxol-4-yl)piperidin-1-yl)methyl)-1-((1-ethyl-1H-imidazol-5-yl)methyl)-1H-benzo[d]imidazole-6-carboxylate. CAS No. 2401892-86-0. Molecular formula: C34H36ClFN6O4. Mole weight: 647.14. | |
| GLP-1 receptor agonist 9 | GLP-1 receptor agonist 9 is an agonist of GLP-1 receptor. (Extracted from WO2020234726 A1, example 7). Synonyms: 1H-Benzimidazole-6-carboxylic acid, 2-[[4-[(2S)-2-(4-chloro-2-fluorophenyl)-2-methyl-1,3-benzodioxol-4-yl]-1-piperidinyl]methyl]-1-[(2S)-2-oxetanylmethyl]-. Grade: ≥95%. CAS No. 2401892-71-3. Molecular formula: C32H31ClFN3O5. Mole weight: 592.06. | |
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