A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
L-Cystine bis(tert-butyl ester) dihydrochloride ≥95% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Worldwide
L-Cystine BP/EP/FCC/USP
L-Cystine BP/EP/FCC/USP. CAS No. 56-89-3. Molecular formula: C6H12N2O4S2.
L-Cystine-d4
L-Cystine-d4 is the deuterium labeled L-Cystine. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes. Uses: Scientific research. Category: Signaling pathways. CAS No. 1192736-38-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N0394S1.
L-(-)-Cystine dihydrochloride
L-(-)-Cystine dihydrochloride. Alternative Names: (H-Cys-OH)2·2HCl. CAS No. 30925-07-6. Purity: >98.0%. Product ID: FFC-AR-30925076. Molecular formula: C6H13ClN2O4S2. Mole weight: 276.75. IUPAC Name: (2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]disulfanyl]propanoic acid;dihydrochloride. Alfa Chemistry - ISO 9001:32057 Certified.
L-Cystine dihydrochloride
L-Cystine dihydrochloride. CAS No. 30925-07-6. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
L-Cystine dihydrochloride
L-Cystine is a non-essential amino acid for human development. L-Cystine is formed by the dimerization of two cysteines through the sulfur. Synonyms: L-Cystine, hydrochloride (1:2); Cystine, dihydrochloride, L-; Cystine dihydrochloride; (2R,2'R)-3,3'-disulfanediylbis(2-aminopropanoic acid) dihydrochloride. Grade: ≥95%. CAS No. 30925-07-6. Molecular formula: C6H12N2O4S2.2HCl. Mole weight: 313.22.
L-Cystine dihydrochloride
L-Cystine dihydrochloride is the dihydrochloride salt form of L-Cystine (HY-N0394). L-Cystine dihydrochloride elevates Nrf2 protein expression and activates Nrf2 transcription factor. L-cystine dihydrochloride reduces ROS generation and protects against oxidant- or Doxorubicin (HY-15142A)-induced apoptosis. L-Cystine dihydrochloride combined with L-theanine (HY-15121) enhances the production of antigen-specific IgG by increasing glutathione (GSH) levels and T helper 2 (Th2) mediated responses in mice. L-Cystine dihydrochloride is promising for research of cystinuria and kidney stones[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 30925-07-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-W009203.
L-Cystine dihydrochloride
L-Cystine dihydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 13059-63-7. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. Molecular Formula: C6H14Cl2N2O4S2. US Biological Life Sciences.
Worldwide
L-Cystine dihydrochloride
100g Pack Size. Group: Biochemicals. Formula: C6H12N2O4S2 · 2HCl. CAS No. 30925-07-6. Prepack ID 22601431-100g. Molecular Weight 313.22. See USA prepack pricing.
L-Cystine Dihydrochloride (non-animal)
Non-animal sourced L-cystine is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. Group: Biochemicals. Alternative Names: (H-Cys-OH)2.2HCl. Grades: Cell Culture Grade. CAS No. 30925-07-6. Pack Sizes: 25g, 100g, 500g, 1Kg. Molecular Formula: C6H12N2O4S2 2HCl, Molecular Weight: 313.22. US Biological Life Sciences.
Worldwide
L-Cystine dihydrochloride, non-animal 99+%
L-Cystine dihydrochloride, non-animal 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25g, 100g, 250g, 1Kg. US Biological Life Sciences.
Worldwide
L-Cystine dimethyl ester dihydrochloride
L-Cystine dimethyl ester dihydrochloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 32854-09-4. Pack Sizes: 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
L-Cystine dimethyl ester dihydrochloride
L-Cystine dimethyl ester dihydrochloride serves as an efficacious antioxidant, exhibiting commendable immunomodulatory, metabolic and cytoprotective potential. Its application is extended towards abating oxidative stress, addressing cardiovascular complications, and counteracting hepatic insult instigated by noxious agents. In essence, this compound offers a multifaceted therapeutic approach to sustain homeostatic balance in cellular milieu. Synonyms: Dimethyl L-cystinate dihydrochloride; (2R,2'R)-Dimethyl 3,3'-disulfanediylbis(2-aminopropanoate) dihydrochloride; Dimethyl 3,3'-disulfanediyl(2R,2'R)-bis(2-aminopropanoate) dihydrochloride; NSC 161614; L-cysteine methyl ester (1->1')-disulfide compound with L-cysteine methyl ester hydrochloride. Grade: >95%. CAS No. 32854-09-4. Molecular formula: C8H18Cl2N2O4S2. Mole weight: 341.28.
L-Cystine-dimethyl Ester Dihydrochloride
L-Cystine-dimethyl Ester Dihydrochloride. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
L-Cystine Disodium Anhydrous (H-L-Cys-OH*NH2)
L-Cystine Disodium Anhydrous (H-L-Cys-OH*NH2). Group: Biochemicals. Alternative Names: H-L-Cys-OH*NH2; 2-amino-3-[ (2-amino-2-carboxylatoethyl) disulfanyl]propanoate Disodium. Grades: Cell Culture Grade. CAS No. 647404-23-0. Pack Sizes: 100g, 250g, 500g. Molecular Formula: C6H10N2O4S2Na2, Molecular Weight: 284.3. US Biological Life Sciences.
L-Cystine Disodium Salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 64704-23-0. Pack Sizes: 500mg, 1g. Molecular Formula: C6H10N2Na2O4S2, Molecular Weight: 284.26. US Biological Life Sciences.
Worldwide
L-Cystine Disodium Salt Monohydrate
L-Cystine Disodium Salt Monohydrate. Synonyms: 7308AH. CAS No. 199329-53-8. Molecular formula: C6H10N2O4S2·2Na·H2O. Mole weight: 302.28.
L-Cystine disodium salt synthetically derived
100g Pack Size. Group: Amino Acids. Formula: C6H10N2Na2O4S2. CAS No. 64704-23-0. Prepack ID 52105905-100g. Molecular Weight 284.26. See USA prepack pricing.
L-Cytidine
L-Cytidine. Group: Biochemicals. Alternative Names: 1- (b-L-ribofuranosyl) cytosine. Grades: Highly Purified. CAS No. 26524-60-7. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C9H13N3O5. US Biological Life Sciences.
Worldwide
LCZ696 (valsartan + sacubitril) impurity 1
LCZ696 (valsartan + sacubitril) impurity 1. Uses: For analytical and research use. Alternative Names: Calcium 4-(((2R,4S)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate. Molecular formula: 2(C24H28NO5)·Ca. Mole weight: 861.04. Catalog: APB01854.
LCZ696 (valsartan + sacubitril) impurity 19
LCZ696 (valsartan + sacubitril) impurity 19. Uses: For analytical and research use. Alternative Names: (2S,4R)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid. CAS No. 1012341-54-6. Molecular formula: C23H29NO4. Mole weight: 383.48. Catalog: APB1012341546.
LCZ696 (valsartan + sacubitril) impurity 2
LCZ696 (valsartan + sacubitril) impurity 2. Uses: For analytical and research use. Alternative Names: Calcium 4-(((2S,4S)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate. Molecular formula: 2(C24H28NO5)·Ca. Mole weight: 861.04. Catalog: APB01853.
LCZ696 (valsartan + sacubitril) impurity 20
LCZ696 (valsartan + sacubitril) impurity 20. Uses: For analytical and research use. Alternative Names: (2R,4R)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid. CAS No. 1012341-56-8. Molecular formula: C23H29NO4. Mole weight: 383.48. Catalog: APB1012341568.
LCZ696 (valsartan + sacubitril) impurity 21
LCZ696 (valsartan + sacubitril) impurity 21. Uses: For analytical and research use. Alternative Names: (2S,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid. CAS No. 1012341-52-4. Molecular formula: C23H29NO4. Mole weight: 383.48. Catalog: APB1012341524.
LCZ696 (valsartan + sacubitril) impurity 29
LCZ696 (valsartan + sacubitril) impurity 29. Uses: For analytical and research use. Alternative Names: (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate. CAS No. 1426129-50-1. Molecular formula: C20H25NO3. Mole weight: 327.42. Catalog: APB1426129501.
LCZ696 (valsartan + sacubitril) impurity 3
LCZ696 (valsartan + sacubitril) impurity 3. Uses: For analytical and research use. Alternative Names: Calcium 4-(((2R,4R)-1-([1,1'-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate. Molecular formula: 2(C24H28NO5)·Ca. Mole weight: 861.04. Catalog: APB01852.
LD4172
LD4172 is a selective RIPK1 PROTAC degrader with a Ki of 4.8 nM. LD4172 induces RIPK1 protein degradation via ternary complex formation with RIPK1 and VHL E3 ligase, driving ubiquitination and proteasomal breakdown. LD4172 abrogates TNF-induced classical NF-κB signaling in TRAF2-deficient cells, impairing IκBα phosphorylation and degradation, and reducing IL-8 production. LD4172 induces apoptosis and immunogenic cell death in tumor cells, enhances tumor-infiltrating lymphocyte responses, and sensitizes tumors to anti-PD1 therapy. LD4172 acts as a chemical probe for investigating RIPK1 scaffolding functions. LD4172 can be used for the research of melanoma, colon cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2782022-40-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-153598.
L-DABA
L-DABA, (L-2,4-Diaminobutyric acid) is a noncompetitive GABA transaminase inhibitor (IC50 > 500 μM) with antitumor activity in vivo and in vitro. Synonyms: (2S)-2,4-diaminobutanoic acid; 2,4-diaminobutyric acid; 2,4-diaminobutyric acid dihydrochloride, (+-)-isomer; 2,4-diaminobutyric acid dihydrochloride, (S)-isomer; 2,4-diaminobutyric acid monohydrochloride, (+-)-isomer; 2,4-diaminobutyric acid monohydrochloride, (S)-isomer; 2,4-diaminobutyric acid, (+)-isomer; 2,4-diaminobutyric acid, (+-)-isomer; 2,4-diaminobutyric acid, (R)-isomer; 2,4-diaminobutyric acid, (S)-isomer; L-2,4-diaminobutyric acid. CAS No. 1758-80-1. Molecular formula: C4H10N2O2. Mole weight: 118.13.
LDC000067 is a highly specific CDK9 inhibitor with an IC50 value of 44±10 nM in vitro. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LDC067. CAS No. 1073485-20-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15878.
LDC1267
LDC1267 is a highly selective TAM (Tyro3, Axl and Mer) kinase inhibitor with IC50s of <5 nM/8 nM/29 nM for Tyro3,Axl and Mer respectively[1].5>. Uses: Scientific research. Category: Signaling pathways. CAS No. 1361030-48-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12494.
LDC3140
LDC3140 is a selective CDK7 inhibitor (IC50<5 nM). By inhibiting the activity of CDK7, LDC3140 affects the regulation of the cell cycle, leading to cell cycle arrest and thus inhibiting the proliferation of tumor cells. LDC3140 can be used in the research of cancer treatment[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1453833-30-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18969.
LDC4297
LDC4297 is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. LDC4297 inhibits human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. LDC4297 shows broad antiviral activities to Herpesviridae, Adenoviridae, Poxviridae, Retroviridae and Orthomyxoviridae with EC50 value of 0.02-1.21 μM. LDC4297 can be used for the research of infection[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1453834-21-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12653.
LDC4297 hydrochloride
LDC4297 hydrochloride is a selective inhibitor of CDK7 with an IC50 value of 0.13 nM. LDC4297 hydrochloride inhibits human cytomegalovirus (HCMV) replication with an EC50 value of 24.5 nM. LDC4297 hydrochloride shows broad antiviral activities to Herpesviridae, Adenoviridae, Poxviridae, Retroviridae and Orthomyxoviridae with EC50 values of 0.02-1.21 μM. LDC4297 hydrochloride can be used for the research of infection[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2319747-14-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12653A.
LDC7559
LDC7559 is a gasdermin D (GSDMD) inhibitor via blocking neutrophil extracellular trap (NET) in the late stages [1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2407782-01-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111674.
L-Dehydro ascorbic acid
L-Dehydro ascorbic acid. Group: Biochemicals. Alternative Names: Dehydro-L-ascorbic acid; L-threo-2,3-hexodiulosonic acid gamma-lactone; Oxidized ascorbic acid. Grades: Highly Purified. CAS No. 490-83-5. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C6H6O6. US Biological Life Sciences.
Worldwide
L-Dehydro Ascorbic Acid-[13C6]
L-Dehydro Ascorbic Acid-[13C6] is the labelled analogue of L-Dehydro Ascorbic Acid, which is the reversibly oxidized form of ascorbic acid. Synonyms: L-Dehydro Ascorbic Acid-13C6; Dehydro-L-ascorbic Acid-13C6; L-threo-2,3-Hexodiulosonic Acid-13C6 γ-Lactone; Oxidized Ascorbic Acid-13C6; Oxidized Vitamin C-13C6. CAS No. 1217529-45-7. Molecular formula: [13C]6H6O6. Mole weight: 180.06.
L-demethylnoviosyl transferase
The enzyme is involved in the biosynthesis of the aminocoumarin antibiotic, novobiocin. Group: Enzymes. Synonyms: novM (gene name); dTDP-β-L-noviose:novobiocic acid 7-O-noviosyltransferase; L-noviosyl transferase. Enzyme Commission Number: EC 2.4.1.302. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2537; L-demethylnoviosyl transferase; EC 2.4.1.302; novM (gene name); dTDP-β-L-noviose:novobiocic acid 7-O-noviosyltransferase; L-noviosyl transferase. Cat No: EXWM-2537.
L-Dierucoyl Lecithin
L-Dierucoyl Lecithin is a phospholipid that is used in the formation of netural lipid bilayer membranes for the purposes of research and experimentation in the fields of biology and biochemistry. L-Dierucoyl Lecithin is a derivative of Lecithin, a phospholipid that is an important component of naturally occurring, biological membranes. Group: Biochemicals. Grades: Highly Purified. CAS No. 51779-95-4. Pack Sizes: 250mg, 2.5g. Molecular Formula: C52H100NO8P, Molecular Weight: 898.33. US Biological Life Sciences.
Worldwide
L-Dierucoyl Lecithin-D9
L-Dierucoyl Lecithin-D9 is a labelled analogue of L-Dierucoyl Lecithin (D441945). L-Dierucoyl Lecithin is a phospholipid that is used in the formation of netural lipid bilayer membranes for the purposes of research and experimentation in the fields of biology and biochemistry. L-Dierucoyl Lecithin is a derivative of Lecithin, a phospholipid that is an important component of naturally occurring, biological membranes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C26H39D9NO8P, Molecular Weight: 542.69. US Biological Life Sciences.
Worldwide
L-Dihydroorotic acid
L-Dihydroorotic acid is an important intermediate in the metabolism of orotic acid and a substrate of dihydroorotate dehydrogenase (DHODH). L-Dihydroorotic acid can reversibly hydrolyze to yield the acyclic L-ureidosuccinic acid by dihydrowhey enzyme[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5988-19-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-W015495.
L-Dihydroorotic acid (Standard)
L-Dihydroorotic acid (Standard) is an analytical reference standard for L-Dihydroorotic acid. This product is used for research and analytical applications. L-Dihydroorotic acid is an important intermediate in the metabolism of orotic acid and a substrate of dihydroorotate dehydrogenase (DHODH). L-Dihydroorotic acid can reversibly hydrolyze to yield the acyclic L-ureidosuccinic acid by dihydrowhey enzyme[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5988-19-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W015495R.
L-Dithiothreitol
L-Dithiothreitol. Group: Biochemicals. Grades: Reagent Grade. CAS No. 16096-97-2. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
L-(-)-Dithiothreitol
L-(-)-Dithiothreitol. Group: Biochemicals. Alternative Names: (-)-Cleland's Reagent; L-DTT. Grades: Highly Purified. CAS No. 16096-97-2. Pack Sizes: 1g, 2g, 5g. Molecular Formula: C4H10O2S2. US Biological Life Sciences.
LDN193189 (DM-3189) is a potent selective BMP type I receptor (BMP I) inhibitor. LDN193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DM-3189. CAS No. 1062368-24-4. Pack Sizes: 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12071.
LDN-193189
LDN-193189 (DM3189) is a selective BMP signaling inhibitor, inhibits the ALK1, ALK2, ALK3 and ALK6 with IC50s of 0.8 nM, 0.8 nM, 5.3 nM and 16.7 nM in the kinase assay, respectively. LDN-193189 inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50s of 5 nM and 30 nM in C2C12 cells, respectively, exhibits 200-fold selectivity for BMP versus TGF-β. For cell testing, the water-soluble S7507 LDN-193189 2HCl is recommended.This product has poor solubility, animal experiments are available, cell experiments please choose carefully! Group: Inhibitors. Alternative Names: DM3189. CAS No. 1062368-24-4. Pack Sizes: 2mg. Product ID: S2618. Formula: C25H22N6. Smiles: C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC6=CC=CC=C56)N=C3. Storage Conditions: 2 years -80 in solvent.
United States; Europe
LDN193189 dihydrochloride
LDN193189 (DM-3189) dihydrochloride is a potent selective BMP type I receptor (BMP I) inhibitor. LDN193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DM-3189 dihydrochloride. CAS No. 1435934-00-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12071B.
LDN-193189 Dihydrochloride
LDN-193189 (DM3189) 2HCl is a selective BMP signaling inhibitor, inhibits the ALK1, ALK2, ALK3 and ALK6 with IC50s of 0.8 nM, 0.8 nM, 5.3 nM and 16.7 nM in the kinase assay, respectively. LDN-193189 inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50s of 5 nM and 30 nM in C2C12 cells, respectively, exhibits 200-fold selectivity for BMP versus TGF-β. Group: Inhibitors. Alternative Names: DM-3189 2HCl. CAS No. 1435934-00-1. Pack Sizes: 5mg. Product ID: S7507. Formula: C25H24Cl2N6. Smiles: C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC6=CC=CC=C56)N=C3.Cl.Cl. Storage Conditions: 2 years -80 in solvent.
United States; Europe
LDN193189 (GMP)
LDN193189 GMP is LDN193189 (HY-12071) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. LDN193189 (DM-3189) is a potent selective BMP type I receptor (BMP I) inhibitor. LDN193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DM-3189 (GMP). CAS No. 1062368-24-4. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-12071G.
LDN193189 hydrochloride
LDN193189 (DM-3189) hydrochloride is a potent selective BMP type I receptor (BMP I) inhibitor. LDN193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DM-3189 hydrochloride. CAS No. 1062368-62-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12071C.
LDN193189 Tetrahydrochloride
LDN193189 (DM-3189) Tetrahydrochloride is a potent selective BMP type I receptor (BMP I) inhibitor. LDN193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DM-3189 Tetrahydrochloride. CAS No. 2310134-98-4. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-12071A.
LDN 209929 dihydrochloride
LDN 209929 dihydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
LDN-209929 dihydrochloride
LDN-209929 dihydrochloride is a potent and selective haspin kinase inhibitor (IC50=55 nM) with180-fold selectivity verses DYRK2 (IC50=9.9 μM). LDN-209929 is a optimized analogue of LDN-192960 (HY-13455)[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1784281-97-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110320.
A pyrazolo[1,5-a]pyridine derivative that acts as an potent and reversible EphB3 receptor tyrosine kinase inhibitor with an IC50 of 79nM with good mouse liver microsomal stability and aqueous solubility. Shown to suppress EphB3-induced autophosphorylation of EphB3 receptor at 10uM in cells. When profiled against a panel of 288 kinases at 5uM, found to also inhibit most of the Eph (Erythropoietin-producing hepatocellular carcinoma) receptor kinases including EphA1, EphA2, EphA3, EphA4, EphA5, EphA8, EphB1, EphB2, EphB3, EphB4 and other tyrosine kinases, but not EphA6 and EphA7, and is non-inhibitory towards non-RTK kinases screened except for p38α, p38b, and Qik. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C??H??ClN?O?, Molecular Weight: 444.9. US Biological Life Sciences.
Worldwide
LDN 212320
LDN 212320. Group: Biochemicals. Grades: Purified. CAS No. 894002-50-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
LDN-212320
LDN-212320 (LDN-0212320) is a glutamate transporter (GLT-1)/excitatory amino acid transporter 2 (EAAT2) activator (at translational level). LDN-212320 (LDN-0212320) prevents nociceptive pain by upregulating astroglial GLT-1 expression in the hippocampus and ACC[1]
LDN-212854
LDN-212854 is a bone morphogenetic protein (BMP) inhibitor that potently inhibits ALK2 (IC50: 1.3 nM). LDN-212854 also inhibits ALK1 (IC50: 2.40 nM). LDN-212854 can be used in the research of fibrodysplasia ossificans progressive and cancers, such as hepatocellular carcinoma (HCC)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1432597-26-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-15897.
LDN-214117
LDN-214117 is an orally active ALK2 inhibitor with well-tolerated and good brain penetration. LDN-214117 has a high selectivity and low cytotoxicity for ALK2 with an IC50 value of 24 nM. LDN-214117 also is a specific bone morphogenetic proteins (BMPs) signaling inhibitor and has relatively selective inhibition for BMP6 with an IC50 value of 100 nM. LDN-214117 can be used for the research of fibrodysplasia ossificans progressiva (FOP), diffuse intrinsic pontine glioma (DIPG) [1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1627503-67-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16712.
LDN 27219
LDN 27219. Group: Biochemicals. Grades: Purified. CAS No. 312946-37-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
LDN-27219
LDN-27219 is a reversible, slow-binding inhibitor of TGase. LDN-27219 inhibits human TGase with an IC50 value of 0.6 μM. LDN-27219 effectively decreases blood pressure and induces vasodilation, it can be used for the research of cardiovascular disease[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 312946-37-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16693.
LDN 57444
LDN 57444. Group: Biochemicals. Alternative Names: 5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-2,3-dione 3-(O-Acetyloxime). Grades: Highly Purified. CAS No. 668467-91-2. Pack Sizes: 10mg. Molecular Formula: C17H11Cl3N2O3, Molecular Weight: 397.64. US Biological Life Sciences.
Worldwide
LDN-57444
LDN-57444 is a reversible, competitive and site-directed inhibitor of ubiquitin C-terminal hydrolase L1 (UCH-L1), with an IC50 of 0.88 μM and a Ki of 0.40 μM; LDN-57444 also suppresses UCH-L3 activity, with an IC50 of 25 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 668467-91-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18637.
L-DOPA
L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease[1][2][3]. Uses: Scientific research. Category: Induced disease models products. Alternative Names: Levodopa; 3,4-Dihydroxyphenylalanine. CAS No. 59-92-7. Pack Sizes: 200 mg; 1 g. Product ID: HY-N0304.